[Detection of HIV virus antibodies in saliva] NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

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[Detection of HIV virus antibodies in saliva]

Epidemiol Mikrobiol Imunol. 1995 Sep;44(3):127-9. Unique Identifier : AIDSLINE MED/96084472
Bruckova M; Stankova M; Centrum AIDS, Infekcni klinika 1. lekarske fakulty; Univerzity Karlovy, Fakultni nemocnice na Bulovce, Praha.

Abstract: The authors evaluate the use of saliva as alternative biological material for detection of HIV antibodies. If collected properly and when using the appropriate ELISA methods, HIV antibodies can be assessed in saliva with considerable sensitivity and specificity. Testing in saliva eliminates many disadvantages found when assessing HIV antibodies in serum. It does not require trained staff for blood sampling, collection and processing of saliva reduces the risk of professional infection to a minimum and can be carried out also under field conditions. A great advantage is the easy and unpretentious transport of collected samples to the laboratory, even long distance transport at extreme temperatures (transport medium in the testing kit Omni-SAL ensures great stability of the sample as well as proper collection of the sample). Alternative testing in saliva is useful in particular for epidemiological surveillance and for screening of HIV antibodies in population groups with a high risk of infections such as drug users and commercial works where it is often very difficult to obtain blood samples for examination.
Keywords: English Abstract Enzyme-Linked Immunosorbent Assay Human HIV Antibodies/*ANALYSIS Saliva/*VIROLOGY Sensitivity and Specificity JOURNAL ARTICLEKWDenglishabstractenzyme-linkedimmunosorbentassayhumanhivantibodies/KWDanalysissaliva/KWDvirologysensitivityandspecificityjournalarticle
960330
M9630743

Copyright © 1996 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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