Localized retroperitoneal fibromatosis causing intestinal obstruction in a cynomolgus monkey (Macaca fascicularis). NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

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Localized retroperitoneal fibromatosis causing intestinal obstruction in a cynomolgus monkey (Macaca fascicularis).

Vet Pathol. 1995 Nov;32(6):713-6. Unique Identifier : AIDSLINE MED/96162837
Fikes JD; O'Sullivan MG; Department of Comparative Medicine, Bowman Gray School of; Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1040,; USA.

Abstract: Gross examination of a 24-month-old, male cynomolgus monkey (Macaca fascicularis) revealed obstruction of the ileum by a mass that entrapped and compressed the ileocecal junction. The mass was well circumscribed, firm, and white on cut surface. Histologically, the mass consisted of spindle-shaped cells arranged in interweaving bundles or as narrow cords and individual cells widely separated by dense collagen. A diagnosis of localized retroperitoneal fibromatosis was made based on the characteristic gross and microscopic findings and isolation of type D simian retrovirus, serotype-2, from spleen and mesenteric lymph node. Monkeys with localized retroperitoneal fibromatosis generally exhibit signs only of a palpable mass at the ileocecal junction and/or nonspecific diarrhea. This case represents an unusual presentation of localized retroperitoneal fibromatosis in which the lesion produced intestinal obstruction and death.
Keywords: Animal Case Report Collagen/ANALYSIS Fatal Outcome Ileal Diseases/ETIOLOGY/PATHOLOGY/VETERINARY Ileocecal Valve/*PATHOLOGY Ileum/CHEMISTRY/PATHOLOGY Intestinal Obstruction/ETIOLOGY/PATHOLOGY/*VETERINARY Lymph Nodes/PATHOLOGY/VIROLOGY *Macaca fascicularis Male Monkey Diseases/*ETIOLOGY/PATHOLOGY Retroperitoneal Fibrosis/COMPLICATIONS/PATHOLOGY/*VETERINARY Retroviruses Type D, Simian/ISOLATION & PURIF Spleen/PATHOLOGY/VIROLOGY Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE

KWDanimalcasereportcollagen/analysisfataloutcomeilealdiseases/etiology/pathology/veterinaryileocecalvalve/KWDpathologyileum/chemistry/pathologyintestinalobstruction/etiology/pathology/KWDveterinarylymphnodes/pathology/virologyKWDmacacafascicularismalemonkeydiseases/KWDetiology/pathologyretroperitonealfibrosis/complications/pathology/KWDveterinaryretrovirusestyped,simian/isolation&purifspleen/pathology/virologysupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
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