Intrathoracic lymphoproliferative disorders in the immunocompromised patient: CT findings. NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Intrathoracic lymphoproliferative disorders in the immunocompromised patient: CT findings.

Radiology. 1995 Oct;197(1):53-8. Unique Identifier : AIDSLINE MED/96023123
Carignan S; Staples CA; Muller NL; Department of Radiology, University of British Columbia,; Vancouver, Canada.

Abstract: PURPOSE: To assess the computed tomographic (CT) findings of intrathoracic lymphoproliferative disorders in the immunocompromised patient. MATERIALS AND METHODS: The authors retrospectively reviewed CT scans of the chest in 18 consecutive patients with pathologically proved intrathoracic lymphoproliferative disorders. Twelve patients had the acquired immunodeficiency syndrome (AIDS), and six were receiving immunosuppressive therapy. Final diagnosis included AIDS-related diffuse lymphoid hyperplasia (n = 1), lymphocytic interstitial pneumonia (LIP) (n = 3), posttransplantation lymphoproliferative disorders (PTLDs) (n = 4), and lymphoma (n = 10). RESULTS: Diffuse areas of ground-glass attenuation were found in the patient with lymphoid hyperplasia and the three patients with LIP. The four patients with PTLDs had multiple, well-circumscribed pulmonary nodules, and nodules in three of the four patients had a halo of ground-glass attenuation. Nine of the 10 patients with lymphoma had well-circumscribed nodules or nodules with consolidation. Mediastinal lymph node enlargement was present in two patients with PTLDs and three patients with lymphoma. CONCLUSION: The intrathoracic CT findings of lymphoproliferative disorders appear to be similar in immunocompromised patients with and without AIDS and are usually extranodal.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/RADIOGRAPHY Adult Aged Female Human *Immunocompromised Host Immunosuppressive Agents/ADVERSE EFFECTS Liver Transplantation Lung Diseases, Interstitial/COMPLICATIONS/RADIOGRAPHY Lymphoma, AIDS-Related/RADIOGRAPHY Lymphoproliferative Disorders/COMPLICATIONS/*RADIOGRAPHY Male Middle Age Postoperative Complications Tomography, X-Ray Computed JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complications/radiographyadultagedfemalehumanKWDimmunocompromisedhostimmunosuppressiveagents/adverseeffectslivertransplantationlungdiseases,interstitial/complications/radiographylymphoma,aids-related/radiographylymphoproliferativedisorders/complications/KWDradiographymalemiddleagepostoperativecomplicationstomography,x-raycomputedjournalarticle
960130
M9610187

Copyright © 1996 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1996. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1996. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .