1996

Infectious diseases update. [videorecording]: Chicago, Ill. : Teach'em, [1995] 3 videocassettes : sd., col. ; 1/2 in (Science & city lights) Unique Identifier : AIDSLINE AV/9517186; Silverman S
D.A.I.R. update.: San Francisco, Calif. : The Foundation, v Unique Identifier : AIDSLINE CAT/9440713
[AIDS, hepatitt-B, veiledende forholdsregler for hindring av smitteoverforing av HIV og HBV i tannhelsetjenesten.]: [Oslo] : Helsedirektoratet, 1986 40 p. : ill (AIDS-skriv ; nr. 19) Unique Identifier : AIDSLINE CAT/9507340
[AIDS, samling av rundskriv om AIDS og HTLV-iii/LAV.]: [Oslo] : Helsedirektoratet, 1986 36 p (AIDS-skriv ; nr. 17) Unique Identifier : AIDSLINE CAT/9507338
[AIDS, forebygging og kontroll av HIV-infeksjoner : forslag til intensivert malrettet smitteoppsporing og konkrete tiltak og virkemidler rettet mot smittemottakere og smittekilder.]: [Oslo] : Helsedirektoratet, 1987 15 p (AIDS-skriv ; nr. 21) Unique Identifier : AIDSLINE CAT/9507328
[AIDS, retningslinjer for voksenpsykiatrien.]: [Oslo] : Helsedirektoratet, 1988 16 p (AIDS-skriv ; nr. 31) Unique Identifier : AIDSLINE CAT/9507342
[AIDS, helsedirektorens tiltaksplan mot HIV/AIDS-epidemien 1990-1995.]: [Oslo] : Helsedirektoratet, 1990 54 p (AIDS-skriv ; nr. 41) Unique Identifier : AIDSLINE CAT/9507341
[AIDS, retningslinjer for smitteoppsporing ved HIV-infeksjon.]: [Oslo] : Helsedirektoratet, 1990 15 p (AIDS-skriv ; nr. 42) Unique Identifier : AIDSLINE CAT/9507329
[Raingan Kansammana ruang Mattrakan thang kotmai kieokap Kanpongkan lae Khuapkhum Rok 'Et : 28 Mesayon Pho. So. 2532 na hongprachum Saranithet, hoprachum Chulalongkonmahawitthayalai.]: Kanpongkan lae Khuapkhum Rok Et [Bangkok] : Munnithi Chulaphon, [1990] 121 p. : ill Unique Identifier : AIDSLINE CAT/9403289
Women and HIV infection.: Washington, DC : American Public Health Association, c1991 15 p. : ill (APHA/SIA report ; 8) Unique Identifier : AIDSLINE CAT/9404445; Newman RG
Integrated AIDS care : social work and health care : 27th-30th October 1992.: Harare : Compilation & binding, Chashki Enterprises, [1992?] 68 p. : ill (National seminar series) Unique Identifier : AIDSLINE CAT/9512174
[Ai tzu ping : AIDS : huo te hsing mien i ch'ueh hsien tsung ho cheng.] Ti 1 pan.: Ch'ang-ch'un shih : Ch'ang-ch'un ch'u pan she, 1992 2, 2, 11, 277 p. : ill Unique Identifier : AIDSLINE CAT/9514228; Chang S
HIV/AIDS surveillance report. Vol. 5, no. 1-: HIV/AIDS Atlanta, Ga. : U.S. Dept. of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Center for Infectious Diseases, Division of HIV/AIDS ; Rockville, MD : CDC National AIDS Clearinghouse [distributor], 1993- v. : ill Unique Identifier : AIDSLINE CAT/9517597
Oregon HIV/AIDS annual report. 1993-: Portland, OR : Oregon Dept. of Human Resources, Health Division, Center for Disease Prevention & Epidemiology, HIV Program, [1993]- v. : ill Unique Identifier : AIDSLINE CAT/9500561
[Le:SIDA : guide du praticien : diagnostic, prise en charge, traitement.]: Geneve : Editions Medecine & hygiene, c1993 v, 147 p. : ill Unique Identifier : AIDSLINE CAT/9423913; Hirschel B
[SIDA : a sexualidade desprevenida dos portugueses.]: Lisboa ; Nova Iorque : McGraw-Hill, 1993 107 p. : ill Unique Identifier : AIDSLINE CAT/9514847; Lucas JS
AIDS & TB weekly abstracts from conference proceedings.: Atlanta, GA : Henderson Publishers, v Unique Identifier : AIDSLINE CAT/9434926
[Az:AIDS-gondolkodas : egy betegseg tarsadalomrajza.]: [Budapest] : T-Twins Kiado, c1994 172 p (A Szocialpolitikai ertesito konyvtara) Unique Identifier : AIDSLINE CAT/9515090; Lederer P
[Perspectives therapeutiques de l'infection par le HIV au stade precoce.]: Paris : Arnette, 1994 viii, 118 p. : ill Unique Identifier : AIDSLINE CAT/9514120
Putting women in the picture : a final report on the rural women and HIV/AIDS/STD project.: Ballarat : Ballarat and District AIDS Working Party, 1994 94 p. : ill Unique Identifier : AIDSLINE CAT/9516396; Hogan E
Southern Africa TB/HIV Co-infection Conference : regional collaboration in T.B. control : Gaborone Sun, 7-11 November 1994, Gaborone, Botswana.: [Gaborone] : Republic of Botswana, [1994?] 5, 17 p Unique Identifier : AIDSLINE CAT/9515233
[Le:SIDA, combien de divisions? : dossier/enquete.]: Paris : Editions Dagorno, c1994 435 p (Collection Combien de divisions?) Unique Identifier : AIDSLINE CAT/9423805
Controlling AIDS through health promotion.: Washington, D.C. (1255 23rd St., N.W. Washington 20037) : Academy for Educational Development, [1995?] iii, 102 p. : ill Unique Identifier : AIDSLINE CAT/9515224; Smith WA; Helquist M; MacDonald GB; Harding NM
Mycobacterium avium--complete infection : progress in research and treatment.: New York : M. Dekker, c1996 [i.e. 1995] xvii, 316 p. : ill (Lung biology in health and disease ; 87) Unique Identifier : AIDSLINE CAT/9516649; Korvick JA; Benson CA
Pocket reference to hospital-acquired infections.: London ; Science Press, c1995 68 p. : ill Unique Identifier : AIDSLINE CAT/9515968; Ayliffe GA; Babb JR
Manual of HIV/AIDS therapy. 2nd ed.: Fountain Valley, Calif. : Current Clinical Strategies, c1995 111 p Unique Identifier : AIDSLINE CAT/9514854; Peiperl L
Sexually transmitted diseases in Sub-Saharan Africa and associated interactions with HIV.: Washington, D.C. : International Programs Center, Population Division, U.S. Bureau of the Census, [1995] viii, 73 p. : ill., maps (IPC staff paper ; no. 75) Unique Identifier : AIDSLINE CAT/9514549; Stanecki K; Heaton L; Way PO
Skin manifestation of AIDS. 2nd ed.: St.Louis : Mosby ; London : M. Dunitz, c1995 xi, 252 p. : ill Unique Identifier : AIDSLINE CAT/9517537; Penneys NS
AIDS update, 1994-1995 : an annual overview of acquired immune deficiency syndrome.: Englewood Cliffs, N.J. : Prentice Hall, c1995 xliii, 381 p. : ill Unique Identifier : AIDSLINE CAT/9510149; Stine GJ
Program and abstracts of the HIV Infection in Women Conference : setting a new agenda : February 22-24, 1995, Sheraton Washington Hotel, Washington, D.C.: Richmond, VA : Philadelphia Sciences Group, c1995 1 v. (various pagings) Unique Identifier : AIDSLINE CAT/9514779
The:gravest show on earth : America in the age of AIDS.: Boston : Houghton Mifflin, 1995 ix, 399 p Unique Identifier : AIDSLINE CAT/9516783; Burkett E
[Enfants nes de mere seropositive au VIH : aspects psychosociaux et dynamiques familiales.]: Paris : Editions INSERM, c1995 xviii, 157 p. : ill (Questions en sante publique) Unique Identifier : AIDSLINE CAT/9512829; Dumaret AC
Tuberculosis: preventing occupational transmission to health care workers.: AAOHN J. 1995 Sep;43(9):475-81. Unique Identifier : AIDSLINE MED/96024895; Doyle AJ; 1. The anticipated reduction in the incidence of tuberculosis (TB) failed to consider four major factors: the advent of human immunodeficiency virus (HIV); the development of multi-drug resistant TB; the decline in public health services and limited access to health care for those in congregative facilities; and the i
Magnetic resonance spectroscopy in childhood AIDS encephalopathy.: Pediatr Neurol. 1995 May;12(4):277-82. Unique Identifier : AIDSLINE MED/96044396; Pavlakis SG; Lu D; Frank Y; Bakshi S; Pahwa S; Barnett TA; Porricolo ME; Gould RJ; Nozyce ML; Hyman RA; Department of Radiology, North Shore University Hospital,; Manhasset, New York, USA.; Twenty-five children with acquired immunodeficiency syndrome (AIDS) underwent cranial magnetic resonance imaging and proton magnetic resonance spectroscopy. Patients were divided into 2 groups based on clinical parameters: encephalopathy and nonencephalopathy. N-acetyl aspartate/creatine ratios were compared between t
Global aspects of HIV pandemic.: Adv Dent Res. 1995 Jul;9(2):146. Unique Identifier : AIDSLINE MED/96036272; Pindborg JJ; WHO Collaborating Centre for Oral Manifestations of the Human; Immunodeficiency Virus, Dental Department, University Hospital,; Denmark.; Twice a year, the World Health Organization publishes reports on AIDS from member countries. At the most recent publication, 190 countries reported that they had no AIDS cases. The other countries reported 611,589 AIDS cases. The introduction will give a brief account of the HIV epidem
Periodontal problems related to HIV-1 infection.: Adv Dent Res. 1995 Jul;9(2):147-51. Unique Identifier : AIDSLINE MED/96036273; Barr CE; Department of Dental Medicine, Beth Israel Medical Center, New; York 10003, USA.; The prevalence of periodontal diseases in HIV-infected infected persons is unresolved. While numerous reports have been published, the data are conflicting in part due to different populations studied, lack of consensus criteria for disease, study location, and biased samples. This presentation will be a collation of
HIV/AIDS--voluntary testing for pregnant women [news]: Hawaii Nurse. 1995 Mar;2(3):9. Unique Identifier : AIDSLINE MED/96002080
Th1 and Th2 subsets: paradigms lost?: Immunol Today. 1995 Aug;16(8):374-9. Unique Identifier : AIDSLINE MED/96002281; Kelso A; Transplantation Biology Unit, Queensland Institute of Medical; Research, Brisbane, Australia.; The T helper 1 (Th1)/Th2 model has provided a valuable framework to investigate and explain many immune reactions and now pervades current thinking on the regulatory role of T cells. However, individual T cells and clones display remarkable diversity in their cytokine profiles, collectively forming a continuous spectr
The role of IL-12 in the induction of organ-specific autoimmune diseases.: Immunol Today. 1995 Aug;16(8):383-6. Unique Identifier : AIDSLINE MED/96002283; Trembleau S; Germann T; Gately MK; Adorini L; Roche Milano Ricerche, Italy.; The concept that T cells are subdivided into T helper 1 (Th1) and Th2 subsets was recently extended to suggest that Th1 cells contribute to the pathogenesis of several organ-specific autoimmune diseases, whereas Th2 cells inhibit disease development. Here, Sylvie Trembleau and colleagues examine the role of interleuki
Unraveling the neuroimmune mechanisms for the HIV-1-associated cognitive/motor complex.: Immunol Today. 1995 Sep;16(9):441-8. Unique Identifier : AIDSLINE MED/96058254; Nottet HS; Gendelman HE; Dept of Pathology and Microbiology, University of Nebraska; Medical Center, Omaha 68198-5215, USA.; Infection of the brain with human immunodeficiency virus 1 (HIV-1) often leads to the devastating loss of mental faculties. Surprisingly, HIV-1 elicits such brain dysfunction without significantly infecting neurons, astrocytes and oligodendroglia. The target for HIV-1 in the brain is the macrophage, which usually func
Characterization of latent transforming growth factor-beta from human seminal plasma.: Am J Reprod Immunol. 1995 Apr;33(4):282-91. Unique Identifier : AIDSLINE MED/96037778; Nocera M; Chu TM; Department of Diagnostic Immunology Research and Biochemistry,; Roswell Park Cancer Institute, New York State Department of; Health, Buffalo 14263, USA.; PROBLEM: Human seminal plasma is known to exhibit immunosuppressive activity. Transforming growth factor beta (TGF-beta) has been identified as an immunosuppressive factor in human seminal plasma. Biologically active TGF-beta represents a family of 25-kDa homodimeric proteins linked with disulfide bonds. TGF-beta asso
Progression of HIV infection is associated with HLA-DQ antigens in Caucasians and African Americans.: Pathobiology. 1995;63(1):22-41. Unique Identifier : AIDSLINE MED/96055646; Brackin MN; Lewis RE; Brackin BT; Achord A; Henderson H; Crawford M; Cruse JM; Department of Pathology, University of Mississippi Medical; Center, Jackson 39216, USA.; In our previous work with human leukocyte antigen (HLA) association in human immunodeficiency virus (HIV) infection, African Americans (Afr Ams) and Caucasians (Caucs) exhibited HLA markers that were associated with protection or disease. The present study was designed to establish if HLAs were associated with the sev
In vitro proteolysis of the red cell membrane in patients with HIV infection.: Pathobiology. 1995;63(1):42-7. Unique Identifier : AIDSLINE MED/96055647; De Angelis V; Biasinutto C; Pradella P; Steffan A; Spina M; Errante D; De Matteis MC; Vettore L; Servizio Immunotrasfusionale e Analisi Cliniche, IRCCS Centro di; Riferimento Oncologico, Aviano, Italia.; It has been suggested that acquired abnormalities of the red cell membrane due to various injuries [azidothymidine ( AZT ) therapy, immunoglobulin coating of red cells, differentiation abnormalities of erythroid precursors] contribute to the onset of an
[HIV infection and its effects on tuberculosis endemic in Chile]: Bol Oficina Sanit Panam. 1995 Aug;119(2):166-78. Unique Identifier : AIDSLINE MED/96018622; Yanez A; Bachelet M; Valenzuela MT; Valenzuela P; Henriquez A; Child R; Organizacion Panamericana de la Salud, Las Condes, Santiago,; Chile.
Cholangitis: pathogenesis, diagnosis, and treatment.: Curr Clin Top Infect Dis. 1995;15:153-78. Unique Identifier : AIDSLINE MED/96022917; Hanau LH; Steigbigel NH; Albert Einstein College of Medicine, Bronx, New York, USA.
An approach to acute fever and rash (AFR) in the adult.: Curr Clin Top Infect Dis. 1995;15:19-75. Unique Identifier : AIDSLINE MED/96022912; Levin S; Goodman LJ; Department of Internal Medicine, Rush Medical College, Chicago,; Illinois, USA.
Outpatient management of HIV infection in the adult: an update.: Curr Clin Top Infect Dis. 1995;15:301-43. Unique Identifier : AIDSLINE MED/96022923; Boswell SL; Harvard Medical School, Boston, Massachusetts, USA.
Positive selection of T cells.: Curr Opin Immunol. 1995 Apr;7(2):188-95. Unique Identifier : AIDSLINE MED/96053437; Fowlkes BJ; Schweighoffer E; Laboratory of Cellular and Molecular Immunology, National; Institute of Allergy and Infectious Diseases, Bethesda, USA.; In the past year, significant technical developments have provided the opportunity to investigate the more mechanistic features of positive selection. Major progress has been made in determining the structure and function of the early pre-T cell receptor, in defining cell types that mediate positive selection, and in
T helper cell differentiation in immune response.: Curr Opin Immunol. 1995 Jun;7(3):360-6. Unique Identifier : AIDSLINE MED/96057965; Reiner SL; Seder RA; Gwenn Knapp Center for Lupus and Immunology Research, Department; of Medicine, University of Chicago, IL 60637-5420, USA.; Significant progress has been made in understanding the maturation of antigen-specific CD4+ T helper cell responses. Recent progress centers on the network of cytokines, accessory molecules, and cell types that shapes the differentiation of distinct T helper cell subsets. Use of transgenic and knockout mice and well c
Activation-induced death of mature T cells in the regulation of immune responses.: Curr Opin Immunol. 1995 Jun;7(3):382-8. Unique Identifier : AIDSLINE MED/96057968; Russell JH; Department of Molecular Biology and Pharmacology, Washington; University School of Medicine, St Louis, MO 63110, USA.; Deletion of self-reactive clones of immature thymocytes by activation-induced death (AID) is thought to be the primary mechanism for the establishment of self-tolerance in the T-cell compartment. Recent evidence suggests that a genetically distinct but analogous process of AID in mature T cells is important in regulat
Regulation of lymphocyte functions by nitric oxide.: Curr Opin Immunol. 1995 Jun;7(3):396-9. Unique Identifier : AIDSLINE MED/96057970; Liew FY; Department of Immunology, University of Glasgow, UK.; Current interest in nitric oxide is derived from its numerous biological roles. Immunologically, apart from the well known role of nitric oxide in anti-microbial and autoimmune diseases, nitric oxide is now emerging as a potential powerful mediator of T-cell responses. Evidence now shows that nitric oxide can both enh
Preventive therapy for tuberculosis in HIV infection: the promise and the reality [editorial]: AIDS. 1995 Jul;9(7):665-73. Unique Identifier : AIDSLINE MED/96035227; O'Brien RJ; Perriens JH
Distinct HIV-1 long terminal repeat quasispecies present in nervous tissues compared to that in lung, blood and lymphoid tissues of an AIDS patient.: AIDS. 1995 Jul;9(7):675-83. Unique Identifier : AIDSLINE MED/96035228; Ait-Khaled M; McLaughlin JE; Johnson MA; Emery VC; Department of Virology, Royal Free Hospital, London, UK.; OBJECTIVE: To investigate the phylogenetic relationship of HIV-1 proviral long terminal repeat (LTR) variants present in postmortem samples of lymph node, spleen, lung, dorsal root ganglion and spinal cord as well as in the peripheral blood of an HIV-1-infected patient dying with AIDS. DESIGN AND METHODS: Postmortem t
A genetic analysis of HIV-1 from Punjab, India reveals the presence of multiple variants.: AIDS. 1995 Jul;9(7):685-90. Unique Identifier : AIDSLINE MED/96035229; Jameel S; Zafrullah M; Ahmad M; Kapoor GS; Sehgal S; International Center for Genetic Engineering and Biotechnology,; Aruna Asaf Ali Marg, New Delhi, India.; OBJECTIVE: To determine the extent of HIV-1 genetic variation in Indian patients. DESIGN: To avoid any bias in selecting viral variants, HIV-1 DNA was amplified directly from the peripheral blood mononuclear cells of patients and sequenced. Genetic similarity between Indian sequences and other geographic isolates was
In vitro production of type 1 and type 2 cytokines by peripheral blood mononuclear cells from high-risk HIV-negative intravenous drug users.: AIDS. 1995 Jul;9(7):691-4. Unique Identifier : AIDSLINE MED/96035230; Barcellini W; Rizzardi GP; Velati C; Borghi MO; Fain C; Lazzarin A; Meroni PL; Institute of Internal Medicine, Infectious Diseases and; Immunopathology, University of Milan, Italy.; OBJECTIVE: To study type 1 and type 2 cytokine patterns in HIV-negative high-risk intravenous drug users (IVDU). DESIGN: We investigated interleukin (IL)-2, interferon (IFN)-gamma, IL-4, IL-6 and IL-10 production by phytohaemagglutinin (PHA)-stimulated and unstimulated peripheral blood mononuclear cell (PBMC) cultures
Virus-specific antibody production and polyclonal B-cell activation in the intestinal mucosa of HIV-infected individuals.: AIDS. 1995 Jul;9(7):695-700. Unique Identifier : AIDSLINE MED/96035231; Eriksson K; Kilander A; Hagberg L; Norkrans G; Holmgren J; Czerkinsky C; Department of Medical Microbiology and Immunology, University of; Goteborg, Sweden.; OBJECTIVE: To examine possible changes in mucosal B-cell activation status. DESIGN: To examine the frequency and isotype distribution of total and HIV-specific antibody-secreting cells (ASC) in the intestinal mucosa of HIV-infected individuals. METHODS: Mucosal lymphocytes were obtained by enzymatic treatment of duode
Lymphoid tissues targeting of liposome-encapsulated 2',3'-dideoxyinosine.: AIDS. 1995 Jul;9(7):701-7. Unique Identifier : AIDSLINE MED/96035232; Harvie P; Desormeaux A; Gagne N; Tremblay M; Poulin L; Beauchamp D; Bergeron MG; Centre de Recherche en Infectiologie, Centre Hospitalier de; l'Universite Laval, Ste-Foy, Quebec, Canada.; OBJECTIVE: To improve the pharmacokinetics and lymphoid tissues targeting of 2 ,3 -dideoxyinosine (ddI) by encapsulation in liposomes. METHODS: The pharmacokinetics and tissue distribution of free and liposome-encapsulated ddI were determined in C57BL/6 mice following intravenous and subcutaneous administration of a s
Recurrent transient neurological deficits in advanced HIV infection.: AIDS. 1995 Jul;9(7):709-12. Unique Identifier : AIDSLINE MED/96035233; Baily GG; Mandal BK; Department of Infectious Diseases and Tropical Medicine, North; Manchester General Hospital, UK.; OBJECTIVES: To report the occurrence of a syndrome of recurrent neurological deficits in advanced HIV disease and to discuss its management and prognosis. DESIGN: Retrospective case study. SETTING: A regional treatment centre for HIV-infected individuals in northwest England. MAIN OUTCOME MEASURES: Transient neurologi
Relation between stage of disease and neurobehavioral measures in children with symptomatic HIV disease.: AIDS. 1995 Jul;9(7):713-20. Unique Identifier : AIDSLINE MED/96035234; Brouwers P; Tudor-Williams G; DeCarli C; Moss HA; Wolters PL; Civitello LA; Pizzo PA; Pediatric Branch, National Cancer Institute, NIH Clinical Center,; Bethesda, MD 20892-1928, USA.; OBJECTIVE: To study the relationships between stage of HIV disease, reflected by CD4+ lymphocyte percentages and p24 antigen levels, and HIV-associated central nervous system (CNS) abnormalities, measured by computed tomography (CT) brain-scan ratings and neurobehavioral tests. DESIGN: Consecutive case series. SETTING
Maternal HIV infection and infant mortality in Malawi: evidence for increased mortality due to placental malaria infection.: AIDS. 1995 Jul;9(7):721-6. Unique Identifier : AIDSLINE MED/96035235; Bloland PB; Wirima JJ; Steketee RW; Chilima B; Hightower A; Breman JG; Division of Parasitic Diseases, National Center for Infectious; Diseases, Centers for Disease Control and Prevention, Atlanta, GA; 30341-3724, USA.; OBJECTIVES: To examine the relationship between maternal HIV infection, placental malaria infection, and infant mortality as a first step in investigating the possibility of increased vertical transmission of HIV due to placental malaria infection. DESIGN: Retrospective analysis of data from a cohort study of mothers
The predictive value of changes in serologic and cell markers of HIV activity for subsequent clinical outcome in patients with asymptomatic HIV disease treated with zidovudine.: AIDS. 1995 Jul;9(7):727-34. Unique Identifier : AIDSLINE MED/96035236; Jacobson MA; De Gruttola V; Reddy M; Arduino JM; Strickland S; Reichman RC; Bartlett JA; Phair JP; Hirsch MS; Collier AC; et al; Department of Medicine, University of California, San Francisco; General Hospital 94110, USA.; OBJECTIVE: To determine if serologic marker responses to zidovudine treatment during the first year of antiretroviral therapy could predict subsequent HIV disease progression independently of absolute CD4 lymphocyte responses. METHODS: We conducted a case-control study in patients with asymptomatic HIV disease, who we
Sexual behaviour and HIV epidemiology: comparative analysis in France and Britain. The ACSF Group.: AIDS. 1995 Jul;9(7):735-43. Unique Identifier : AIDSLINE MED/96035237; Bajos N; Wadsworth J; Ducot B; Johnson AM; Le Pont F; Wellings K; Spira A; Field J; INSERM U292, Bicetre Hospital, Le Kremlin Bicetre, France.; OBJECTIVE: France and Britain have similar size populations, yet the incidence of AIDS is threefold higher in France. The objective of this study was to compare data from two surveys recently performed in the two countries, in order to determine whether differences in sexual and dr
The social dynamics of HIV transmission as reflected through discordant couples in rural Uganda.: AIDS. 1995 Jul;9(7):745-50. Unique Identifier : AIDSLINE MED/96035238; Serwadda D; Gray RH; Wawer MJ; Stallings RY; Sewankambo NK; Konde-Lule JK; Lainjo B; Kelly R; Institute of Public Health, Makerere University, Kampala, Uganda.; OBJECTIVE: To describe the role of men and women as sources of HIV transmission and to estimate HIV incidence among discordant couples resident in diverse rural communities in Uganda . SETTING: Rakai, a rural district in Uganda, East Africa. METHODS: A population-based cohort study,
AIDS knowledge, risk behaviors, and factors related to condom use among male commercial sex workers and male tourist clients in Bali, Indonesia.: AIDS. 1995 Jul;9(7):751-9. Unique Identifier : AIDSLINE MED/96035239; Ford K; Wirawan DN; Fajans P; Thorpe L; School of Public Health, University of Michigan, Ann Arbor; 48109-2029, USA.; OBJECTIVES: To describe the AIDS/sexually transmitted diseases (STD) knowledge and risk behaviors, and to determine factors related to condom use among male commercial sex workers (CSW) and male tourist clients in Bali, Indonesia . DESIGN: Individual survey interviews were conduc
The HIV/AIDS epidemic in Jamaica.: AIDS. 1995 Jul;9(7):761-8. Unique Identifier : AIDSLINE MED/96035240; Figueroa JP; Brathwaite A; Ward E; DuCasse M; Tscharf I; Nembhard O; Williams E; Ministry of Health, Epidemiology Unit, Kingston, Jamaica.; OBJECTIVE: To describe the HIV/AIDS epidemic in Jamaica . METHODS: Data from the national surveillance system for HIV infection and AIDS based in the Epidemiology Unit, Ministry of Health, were reviewed. These include case reports; HIV screening of blood donors, migrant farmworkers
Predictors of repeat HIV testing among gay and bisexual men.: AIDS. 1995 Jul;9(7):769-75. Unique Identifier : AIDSLINE MED/96035241; Phillips KA; Paul J; Kegeles S; Stall R; Hoff C; Coates TJ; Center for AIDS Prevention Studies, University of California at; San Francisco 94105, USA.; OBJECTIVE: To examine the prevalence and predictors of repeat HIV testing. DESIGN, SETTING AND PARTICIPANTS: Cross-sectional data from two random household-based and bar-based samples of gay/bisexual men in two medium-size cities (Tucson, Arizona and Portland, Oregon) with substantial numbers of AIDS cases, in 1992 (n
The usage and costs of health services for HIV infection in Australia.: AIDS. 1995 Jul;9(7):777-85. Unique Identifier : AIDSLINE MED/96035242; Hurley SF; Kaldor JM; Carlin JB; Gardiner S; Evans DB; Chondros P; Hoy J; Spelman D; Spicer WJ; Wraight H; et al; Department of Public Health and Community Medicine, University of; Melbourne, Victoria, Australia.; OBJECTIVE: To describe patterns of health-service usage and the resulting costs in 1992-1993 for Australian men. DESIGN: A prospective survey, stratified by phase of illness. SETTING: Hospital and community-based care. PATIENTS: A total of 128 homosexual men: 20 in phase 1 (CD4+ count > or = 500 x 10(6)/l), 31 in phas
Hospital costs of treating haemophilic patients infected with HIV.: AIDS. 1995 Jul;9(7):787-93. Unique Identifier : AIDSLINE MED/96035243; Kennelly JM; Tolley KH; Ghani AC; Sabin CA; Maynard AK; Lee CA; Haemophilia Centre, Royal Free Hospital, London, UK.; OBJECTIVE: To calculate the costs of treating HIV-infected haemophilic patients. DESIGN: Two-year retrospective study of hospital-based resource use and costs, from April 1991 to March 1993. SETTING: Haemophilia Centre and Haemostasis Unit, Royal Free Hospital and School of Medicine, London, UK. PATIENTS: Sixty patien
HIV risk behavior among Peace Corps Volunteers.: AIDS. 1995 Jul;9(7):795-9. Unique Identifier : AIDSLINE MED/96035244; Moore J; Beeker C; Harrison JS; Eng TR; Doll LS; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, Georgia 30333, USA.; OBJECTIVE: To describe HIV risk behaviors among Peace Corps Volunteers (PCV) and to examine correlates of sexual risk behaviors. METHOD: Cross-sectional data were collected from 1242 randomly selected PCV serving in 28 countries in 1991. PCV reported the frequency of specific risk behaviors in self-administered questi
Anonymous HIV surveillance with risk factor elicitation at Scotland's largest prison, Barlinnie.: AIDS. 1995 Jul;9(7):801-8. Unique Identifier : AIDSLINE MED/96035245; Bird AG; Gore SM; Cameron S; Ross AJ; Goldberg DJ; Immunology Department, Churchill Hospital, Headington, Oxford,; UK.; OBJECTIVE: To determine prevalence of HIV infection and risk behaviours among male inmates of Her Majesty s Prison (HMP) Barlinnie, Glasgow, Scotland on 8-9 September 1994. DESIGN: Cross-sectional study: voluntary, anonymous HIV surveillance (using saliva samples) of all inmates and linked self-completion risk-factor
Fluconazole-resistant oral candidosis in HIV-infected patients [letter; comment]: AIDS. 1995 Jul;9(7):809-10. Unique Identifier : AIDSLINE MED/96035246; Diz Dios P; Ocampo Hermida A; Miralles Alvarez C; Iglesias Martin I; Otero Varela I
Sorivudine (BV-ara-U) for the treatment of complicated refractory varicella zoster virus infection in HIV-infected patients [letter]: AIDS. 1995 Jul;9(7):810-2. Unique Identifier : AIDSLINE MED/96035247; Burdge DR; Voigt R; Lindley JI; Gage L; Sacks SL
Failure of atovaquone in the treatment of cerebral toxoplasmosis [letter]: AIDS. 1995 Jul;9(7):812-3. Unique Identifier : AIDSLINE MED/96035248; Durand JM; Cretel E; Bagneres D; Guillemot E; Kaplanski G; Soubeyrand J
Angiolymphoid hyperplasia with eosinophils in HIV infection [letter]: AIDS. 1995 Jul;9(7):813-4. Unique Identifier : AIDSLINE MED/96035249; D'Offizi G; Ferrara R; Donati P; Bellomo P; Paganelli R
Fatal Castleman's disease and pulmonary Kaposi's sarcoma in an HIV-seropositive woman [letter]: AIDS. 1995 Jul;9(7):814-6. Unique Identifier : AIDSLINE MED/96035250; Wynia MK; Shapiro B; Kuvin JT; Skolnik PR
Feto-maternal transfer of zidovudine: study on the perfused human placental cotyledon system [letter]: AIDS. 1995 Jul;9(7):816-7. Unique Identifier : AIDSLINE MED/96035251; Giroux M; Berrebi A; Grandjean H; Dumas JC
Recurrent pseudotumor cerebri in an HIV-positive patient [letter]: AIDS. 1995 Jul;9(7):817-9. Unique Identifier : AIDSLINE MED/96035252; Javeed N; Shaikh J; Jayaram S
Progressive multifocal leucoencephalopathy in AIDS: treatment with cytosine arabinoside [letter]: AIDS. 1995 Jul;9(7):819-20. Unique Identifier : AIDSLINE MED/96035253; Guarino M; D'Alessandro R; Rinaldi R; Stracciari A; Pazzaglia P; Costigliola P; Marinacci G; Chiodo F; Di Giandomenico G; Cancellieri C; et al
HIV-1 viraemia and splenectomy [letter]: AIDS. 1995 Jul;9(7):821-2. Unique Identifier : AIDSLINE MED/96035254; Lafeuillade A; Poggi C; Tamalet C; Pellegrino P; Profizi N; Quilichini R; Sayada C
Biological phenotype of HIV-1 and transmission [letter]: AIDS. 1995 Jul;9(7):822-3. Unique Identifier : AIDSLINE MED/96035255; Albert J; Fiore J; Fenyo EM; Pedersen C; Lundgren JD; Gerstoft J; Nielsen C
Savings associated with immediate confirmation of initial high quantitative enzyme immunoassays for HIV [letter]: AIDS. 1995 Jul;9(7):823-4. Unique Identifier : AIDSLINE MED/96035256; Mayo DR; Vance DW; Markowski MA; Kinney A
Progress in anti-HIV structure-based drug design.: Trends Biotechnol. 1995 Oct;13(10):430-8. Unique Identifier : AIDSLINE MED/96030281; Gait MJ; Karn J; MRC Laboratory of Molecular Biology, Cambridge, UK.; The course of drug development for the treatment of HIV-1 infection and AIDS is being revolutionized by high-resolution structures of essential viral proteins. We survey the impact on drug design of the recently elucidated structural knowledge of two essential enzymes, reverse transcriptase and protease, and three new
Recent developments in retro peptides and proteins--an ongoing topochemical exploration.: Trends Biotechnol. 1995 Oct;13(10):438-45. Unique Identifier : AIDSLINE MED/96030282; Chorev M; Goodman M; Department of Pharmaceutical Chemistry, Faculty of Medicine,; Hebrew University, Jerusalem, Israel.; Main-chain peptidomimetics based on peptide-bond reversal and inversion of chirality represent important structural alterations for peptides and proteins, and are highly significant for biotechnology; these modifications have been widely applied: the D-HIV-protease dimer cleaves only all-D substrate; an all-D-hexapept
Some new aspects of molecular mechanisms of cyclosporin A effect on immune response.: APMIS. 1995 Jun;103(6):401-15. Unique Identifier : AIDSLINE MED/96028031; Zav'yalov VP; Denesyuk AI; Lundell J; Korpela T; Institute of Immunology, Lyubuchany, Moscow Region, Russia.; A few protein targets were found to display a specific high-affinity interaction with the immunosuppressant cyclosporin A (CsA): cytosolic cyclophilins (CyP)A, B, C, D, E containing from 122 to 174 amino acid residues in a polypeptide chain, and secreted forms of CyP; CyP-40, 40-kDa CsA-binding polypeptide complexed w
Listeria monocytogenes: a live vector able to deliver heterologous protein within the cytosol and to drive a CD8 dependent T cell response.: Biologicals. 1995 Jun;23(2):135-43. Unique Identifier : AIDSLINE MED/96012508; Goossens PL; Montixi C; Saron MF; Rodriguez M; Zavala F; Milon G; Unite d'Immunophysiologie cellulaire, Institut Pasteur, Paris,; France.; After an introduction on the entry and lifestyle of Listeria monocytogenes within mammalian eucaryotic cells, this chapter gives a brief overview of murine experimental listeriosis. Among the main characteristics of this murine model of infectious/pathogenic processes initiated by a facultative intracellular bacteria,
Sustained-release intravitreal ganciclovir pellets in the treatment of cytomegalovirus retinitis in the acquired immunodeficiency syndrome [letter]: Aust N Z J Ophthalmol. 1995 May;23(2):157-8. Unique Identifier : AIDSLINE MED/96055823; Luckie A; Ai E
Early cytokine production in pulmonary Cryptococcus neoformans infections distinguishes susceptible and resistant mice.: Am J Respir Cell Mol Biol. 1995 Oct;13(4):487-95. Unique Identifier : AIDSLINE MED/96025070; Hoag KA; Street NE; Huffnagle GB; Lipscomb MF; Department of Microbiology, University of Texas Southwestern; Medical Center, Dallas 75235-8576, USA.; A murine pulmonary infection model utilizing intratracheal inoculation of Cryptococcus neoformans was used to analyze cytokines produced in response to opportunistic pathogens acquired via the respiratory tract. The specific question asked was whether early cytokine secretion in lung-associated lymph nodes (LALN) woul
Susceptibility of human monocytes to HIV type 1 infection in vitro is not dependent on their level of CD4 expression.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):769-76. Unique Identifier : AIDSLINE MED/96053838; Sonza S; Maerz A; Uren S; Violo A; Hunter S; Boyle W; Crowe S; AIDS Pathogenesis Research Unit, Macfarlane Burnet Centre for; Medical Research, Fairfield, Victoria, Australia.; Monocytes from HIV-seronegative persons were analyzed for CD4 expression and susceptibility to infection with HIV-1 on the day of isolation and following 1, 2, and 7 days in culture. Although surface CD4 was readily detected on freshly isolated monocytes, these cells were relatively resistant to infection. After 1 to
Contribution of hypervariable domains to the conformation of a broadly neutralizing glycoprotein 120 epitope.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):777-81. Unique Identifier : AIDSLINE MED/96053839; Lee CN; Robinson J; Mazzara G; Cheng YL; Essex M; Lee TH; Department of Cancer Biology, Harvard School of Public Health,; Boston, Massachusetts 02115, USA.; Three of the five hypervariable domains (V1-V3) of human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp120 have previously been shown to be dispensable for antigenic epitopes recognized by broadly neutralizing monoclonal antibodies. In this study, the influence of the V4 and V5 domains on an epitope re
Preparation and characterization of human HIV type 1 neutralizing reference sera.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):783-7. Unique Identifier : AIDSLINE MED/96053840; Vujcic LK; Quinnan GV Jr; Center for Biologics Evaluation and Research, Food and Drug; Administration, Rockville, Maryland 20852-1448, USA.; Reference neutralizing antibody (NA) reagents are needed for laboratories to be able to compare results of neutralization assays that will be used to monitor HIV-1 vaccine recipients. In an effort to establish such reference reagents two asymptomatic, seropositive patients were identified with medium to high amounts o
Frequency of provirus-bearing CD4+ cells in HIV type 1 infection correlates with extent of in vitro apoptosis of CD8+ but not of CD4+ cells.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):789-94. Unique Identifier : AIDSLINE MED/96053841; Carbonari M; Cibati M; Pesce AM; Sbarigia D; Grossi P; D'Offizi G; Luzi G; Fiorilli M; Department of Clinical Medicine, University of Rome La Sapienza,; Italy.; Lymphocytes from HIV-1-infected subjects undergo massive apoptosis when cultured in vitro, and this phenomenon might reflect pathogenetic mechanisms leading to immune dysfunction in vivo. However, (1) lymphocyte death is not restricted to CD4+ cells but seems to involve predominantly CD8+ cells, and (2) the same pheno
Localization of human immunodeficiency virus Rev in transfected and virus-infected cells.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):795-804. Unique Identifier : AIDSLINE MED/96053842; Luznik L; Martone ME; Kraus G; Zhang Y; Xu Y; Ellisman MH; Wong-Staal F; Department of Medicine, UCSD School of Medicine, La Jolla,; California 92093-0665, USA.; The rev gene product of human immunodeficiency virus (HIV) is obligatory for viral replication. Rev interacts specifically with a structured RNA sequence within the viral genome termed the REV response element (RRE). Although the importance of Rev for the expression of viral proteins is well documented, its functional
Decreased thymidine kinase levels in peripheral blood cells from HIV-seropositive individuals: implications for zidovudine metabolism.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):805-11. Unique Identifier : AIDSLINE MED/96053843; Jacobsson B; Britton S; He Q; Karlsson A; Eriksson S; Department of Infectious Diseases, Huddinge Hospital, Sweden.; Azidothymidine (zidovudine, AZT ) used for treatment of HIV infection blocks the viral reverse transcriptase after phosphorylation by cellular enzymes. The first step in this reaction is the formation of AZT monophosphate, primarily catalyzed by host c
Identification of human T cell lymphotropic virus type IIa infection in the Kayapo, an indigenous population of Brazil.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):813-21. Unique Identifier : AIDSLINE GENBANK/U19109; Ishak R; Harrington WJ Jr; Azevedo VN; Eiraku N; Ishak MO; Guerreiro JF; Santos SB; Kubo T; Monken C; Alexander S; et al; Federal University of Para, Belem, Brazil.; Human T cell lymphotropic virus type II (HTLV-II) infection is endemic in a number of indigenous populations in North, Central, and South America. In the present study we have employed serological and molecular methods to identify HTLV-II infection in Indian communities in the Amazon region of
Frequent detection of antibodies against HTLV antigens in patients with AIDS-related non-Hodgkin lymphoma.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):823-7. Unique Identifier : AIDSLINE MED/96053845; Zehender G; Meroni L; Piconi S; De Maddalena C; Parravicini C; Clerici M; Ridolfo AL; Moroni M; Galli M; Clinica delle Malattie Infettive, University of Milan, Italy.; We studied the prevalence of anti-HTLV-I/II antibodies in 22 patients with AIDS-related non-Hodgkin lymphoma (NHL), 453 HIV-1-infected patients without lymphoma (194 of whom were diagnosed as having AIDS), and 6 HIV-1-positive and 75 HIV-1-negative patients with Hodgkin lymphoma. The frequency of serological reactivit
Human foamy virus DNA forms and expression in persistently infected Dami megakaryocytic cells.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):829-36. Unique Identifier : AIDSLINE MED/96053846; Wybier-Franqui J; Tobaly-Tapiero J; Coronel A; Giron ML; Chopin-Robert C; Peries J; Emanoil-Ravier R; UPR A0043, CNRS Retrovirus et Retrotransposons des Vertebres,; Hopital Saint-Louis, Paris, France.; We have characterized human foamy virus (HFV) proviral DNA and determined HFV expression in a persistent infection model, the Dami megakaryocytic cell line. Molecular studies were performed on parental persistently infected cells (Dami-P), as well as on derived clones (Dami-Cl). We report that in these nonlytic and no
Evaluation of murine leukemia virus infection as a model for thrombocytopenia of HIV/AIDS: mechanism of thrombocytopenia and modulation of thrombocytopenia by thrombopoietin.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):837-42. Unique Identifier : AIDSLINE MED/96053847; Sullivan PS; McDonald TP; Department of Animal Science, College of Veterinary Medicine,; University of Tennessee, Knoxville 37901, USA.; Infection of mice with the murine leukemia virus (LP-BM5) was evaluated as a model for the thrombocytopenia of HIV/AIDS. Percent 35S incorporation into platelets, platelet size, platelet count, platelet-associated immunoglobulins (PAIgG), and megakaryocyte size and number were evaluated over a period of 3-9 weeks post
Passive immunization of rhesus macaques against SIV infection and disease.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):843-54. Unique Identifier : AIDSLINE MED/96053848; Gardner M; Rosenthal A; Jennings M; Yee J; Antipa L; Robinson E Jr; Department of Pathology, School of Medicine, University of; California at Davis 95616, USA.; To evaluate the role of humoral immunity against simian immunodeficiency virus (SIV), we tested whether passive immunization with plasma from SIVmac251 vaccine-protected or healthy infected animals would protect rhesus monkeys against intravenous infection with ten 50% animal infectious doses of the cell-free homologo
Genetic construction and in vitro characterization of SIVsmmPBj14-1.9 noninfectious particles.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):855-61. Unique Identifier : AIDSLINE MED/96053849; Deschamps M; Lambrecht B; Horth M; Kummert S; Gelderblom HR; Bruck C; Burny A; Laboratory of Biological Chemistry, Free University of Brussels,; Belgium.
Antisense phosphorothioate oligodeoxynucleotides alter HIV type 1 replication in cultured human macrophages and peripheral blood mononuclear cells.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):863-7. Unique Identifier : AIDSLINE MED/96053850; Weichold FF; Lisziewicz J; Zeman RA; Nerurkar LS; Agrawal S; Reitz MS Jr; Gallo RC; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892, USA.; The use of antisense oligodeoxynucleotides as antiviral drugs to combat HIV-1 infection may offer an alternative to traditional pharmacological therapies. We compared the effects of two 28-mer antisense phosphorothioate oligodeoxynucleotides [PS-oligo(dN)] with non-sequence-specific controls on HIV-1 replication in lo
Human endogenous retrovirus K does not encode mouse mammary tumor virus-related antigens in human breast carcinomas.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):869-72. Unique Identifier : AIDSLINE MED/96053851; Vogetseder W; Denner J; Boller K; Kurth R; Dierich MP; Institut fur Hygiene, Leopold Franzens Universitat, Innsbruck,; Austria.
Nucleotide sequence of the HIV-2 EHO genome, a divergent HIV-2 isolate.: AIDS Res Hum Retroviruses. 1995 Jul;11(7):873-4. Unique Identifier : AIDSLINE MED/96053852; Galabru J; Rey-Cuille MA; Hovanessian AG; Unite de Virologie et Immunologie Cellulaire, Institut Pasteur,; UA CNRS 1157, Paris, France.
Use of recombinant interferon-alpha in human immunodeficiency virus (HIV)-infected individuals.: Biotherapy. 1994;8(1):23-31. Unique Identifier : AIDSLINE MED/96053657; Rivero J; Limonta M; Aguilera A; Fraga M; Lopez Saura P; Santiago de las Vegas Sanatorium, Havana, Cuba.; RATIONALE AND OBJECTIVE: Interferon alpha (IFN-alpha) has anti-retroviral activity and is a possible HIV infection-limiting factor. The aim of this work is to prevent or delay disease progression in asymptomatic Human Immunodeficiency Virus (HIV) carriers. DESIGN AND INTERVENTIONS: Recombinant IFN alpha-2b (3 x 10(6)
Viral arthritis including HIV.: Curr Opin Rheumatol. 1995 Jul;7(4):337-42. Unique Identifier : AIDSLINE MED/96018403; Naides SJ; University of Iowa College of Medicine, Iowa City, USA.; Viruses are attractive candidates for infectious etiologic agents or cofactors in the development of rheumatic diseases. The epidemic of HIV infection and the recognition of emerging viruses continues to fuel interest in the possible role of viruses in the pathogenesis of diseases without defined etiologies. During 19
[Surgery and blood transfusion]: G Chir. 1995 Mar;16(3):132-6. Unique Identifier : AIDSLINE MED/96005308; Catania G; Petralia G; Catalano F; Marzullo E; Dipartimento di Chirurgia, Universita degli Studi di Catania.; Advances in surgery and the extension of the surgical indications have amplified the problems due to hemorrhage, main side effect, and its treatment, which in the past consisted primarily in whole blood transfusion. Such practice, however, involves the surgeon in a series of problems due to shortage of blood donors, r
Reducing the risk of eye contamination.: Nurs Stand. 1995 Sep 13-19;9(51):27-9. Unique Identifier : AIDSLINE MED/96011206; Berry K; The recent case of an Italian nurse waiting for compensation after contracting HIV from a splash to her eye (1) has highlighted the serious risk of contracting infection through the eye conjunctiva. In this article, the author suggests nurses need to take more notice of recommendations and guidelines that they should
A new group (type 3) of Mycobacterium celatum isolated from AIDS patients in the London area.: Int J Syst Bacteriol. 1995 Oct;45(4):861-2. Unique Identifier : AIDSLINE GENBANK/Z46664; Bull TJ; Shanson DC; Archard LC; Yates MD; Hamid ME; Minnikin DE; Medical Microbiology Department, Charing Cross Hospital, London,; England.; We describe a new group (type 3) of the recently proposed species Mycobacterium celatum isolated from eight patients with AIDS in London, England. Sequences of genes coding for 16S rRNA (EMBL accession no. Z46664) showed a divergence of 17 bases from M. celatum type 2 reference isolates and a divergence of 7 bases fro
Resurgence of tuberculosis in children.: Pediatr Pulmonol Suppl. 1995;11:16-7. Unique Identifier : AIDSLINE MED/96037849; Starke JR; Department of Clinical Pediatrics, Baylor College of Medicine,; Texas Children's Hospital, Houston 77030, USA.
Older and newer challenges of tuberculosis in children.: Pediatr Pulmonol Suppl. 1995;11:28-9. Unique Identifier : AIDSLINE MED/96037855; Nahmias AJ; de Sousa A; Freiji R; Lee FK; Division of Pediatric Infectious Diseases, Epidemiology and; Immunology, Emory University, Atlanta, Georgia 30303, USA.; Tuberculosis (TB) in children represents one of the best examples of what we have termed an adultosis--a disease inflicted by adults on children and not by children on adults--and which can be acquired by direct contact or by the indirect result of various types of abuses, such as social ones. The same socioeconomic a
Nontuberculous pulmonary infections in pediatric AIDS.: Pediatr Pulmonol Suppl. 1995;11:3-4. Unique Identifier : AIDSLINE MED/96037843; Bye MR; Department of Pediatrics, Columbia University College of; Physicians and Surgeons, New York, New York 10467, USA.
Clinical and radiological approach of pulmonary diseases in HIV infection in children.: Pediatr Pulmonol Suppl. 1995;11:5-6. Unique Identifier : AIDSLINE MED/96037844; Dollfus C; Geoffray A; Unite d'Hemato-oncologie Pediatrique, Hopital Trousseau,; Paris, France.
Mycobacterium avium intracellulare infection in children with AIDS.: Pediatr Pulmonol Suppl. 1995;11:7-9. Unique Identifier : AIDSLINE MED/96037845; Gershon AA; Department of Pediatrics, Columbia University College of; Physicians & Surgeons, New York, New York 10032, USA.
Classic (non-AIDS-related) Kaposi's sarcoma in a Japanese patient, successfully treated with alpha-2b-interferon [letter]: Br J Dermatol. 1995 Aug;133(2):332-4. Unique Identifier : AIDSLINE MED/96007686; Shimizu S; Tanaka M; Niizeki H; Miyakawa S; Ishiko A; Shimizu H
Co-activation of naive CD4+ T cells and bone marrow-derived mast cells results in the development of Th2 cells.: Int Immunol. 1995 Apr;7(4):525-32. Unique Identifier : AIDSLINE MED/96031348; Huels C; Germann T; Goedert S; Hoehn P; Koelsch S; Hultner L; Palm N; Rude E; Schmitt E; Institut fur Immunologie, University of Mainz, Germany.; Activation of naive dense CD4+ T cells by plate-bound anti-CD3 antibodies favors the development of Th1 cells which, upon re-stimulation, produce significant amounts of IFN-gamma but no IL-4. However, co-activation of such naive T cells in the presence of IgE [anti-dinitrophenyl (DNP)]-loaded bone marrow-derived mast
The protein tyrosine kinase p56lck regulates TCR expression and T cell selection.: Int Immunol. 1995 Apr;7(4):617-24. Unique Identifier : AIDSLINE MED/96031359; Ericsson PO; Teh HS; Department of Microbiology and Immunology, University of British; Columbia, Vancouver, Canada.; The role of the protein tyrosine kinase (PTK), p56lck, in T cell development was evaluated by mating TCR transgenic mice with transgenic mice that expressed lckF505, a constitutively activated form of p56lck which is under the control of the lck proximal promoter element. The TCR transgenic mice expressed either a rec
A CD4+ T cell line-secreted factor, growth promoting for normal and leukemic B cells, identified as thioredoxin.: Int Immunol. 1995 Apr;7(4):625-33. Unique Identifier : AIDSLINE MED/96031360; Rosen A; Lundman P; Carlsson M; Bhavani K; Srinivasa BR; Kjellstrom G; Nilsson K; Holmgren A; Department of Cell Biology, Faculty of Health Sciences,; University of Linkoping, Sweden.; In this study, a B cell growth stimulatory factor, constitutively secreted by a human CD4+ T cell hybridoma clone, MP6, has been purified and characterized. Serum-free 24 h culture media from MP6 cells were collected, concentrated by ultrafiltration and separated by gel chromatography. Fractions were analyzed for stim
Mechanisms of immune tolerance induction through the thymic expression of a peripheral tissue-specific protein.: Int Immunol. 1995 May;7(5):715-25. Unique Identifier : AIDSLINE MED/96053535; Antonia SJ; Geiger T; Miller J; Flavell RA; Department of Immunobiology, Yale University School of Medicine,; New Haven, CT 06510, USA.; A major process through which the immune system becomes tolerant to self proteins involves the deletion of self reactive cells in the thymus. However, T cells reactive to peripheral tissue-specific proteins can escape this deletion and become tolerized in the periphery by a variety of mechanisms. We report here, contr
Sequence heterogeneity of murine acquired immunodeficiency syndrome virus: the role of endogenous virus.: Int Immunol. 1995 May;7(5):861-8. Unique Identifier : AIDSLINE MED/96053548; Gayama S; Vaupel BA; Kanagawa O; Department of Pathology and Medicine, Washington University; School of Medicine, St Louis, MO 63110, USA.; A defective murine leukemia virus is the causative agent of murine acquired immunodeficiency syndrome (MAIDS). We have cloned cDNAs from both virus infected and non-infected cells using the PCR methods with primers corresponding to the franking sequence of the unique p12 gag gene. Sequence analysis of these cDNA clone
Stability of Th1 and Th2 populations.: Int Immunol. 1995 May;7(5):869-75. Unique Identifier : AIDSLINE MED/96053549; Perez VL; Lederer JA; Lichtman AH; Abbas AK; Department of Pathology, Brigham & Women's Hospital, Boston, MA; 02115, USA.; Using an in vitro model for the development of IFN-gamma-producing (Th1) and IL-4-producing (Th2) cells from CD4+ T lymphocytes expressing a transgenic TCR, we show that IL-12 and IL-4 are the most potent stimuli for the differentiation of naive T cells to effector populations. When combinations of cytokines are prese
Mouth operated mucus extractors: safe to use? [letter; comment]: Br J Obstet Gynaecol. 1995 Oct;102(10):845. Unique Identifier : AIDSLINE MED/96046426; Verkuyl DA
Osmotic stress sensitizes sterol-free phospholipid bilayers to the action of Amphotericin B.: Biochim Biophys Acta. 1995 Sep 13;1238(2):156-62. Unique Identifier : AIDSLINE MED/96038199; Wolf BD; Hartsel SC; Department of Chemistry, University of Wisconsin-Eau Claire; 54702-4004, USA.; We have tested the ability of Amphotericin B to form ion channels/defects in osmotically stressed large unilamellar vesicles (LUV) using pyranine fluorescence detected ion/H+ exchange. We found that sterol-free LUV exhibit greatly increased sensitivity to AmB channel formation in the soluble oligomer state (> 0.5 micr
[Comparative imaging of HIV associated diseases of the hepatobiliary system in computerized tomography and cholangiography]: Aktuelle Radiol. 1995 Jul;5(4):216-21. Unique Identifier : AIDSLINE MED/96024247; Knollmann FD; Adler A; Maurer J; Grunewald T; Hintze RE; Schedel H; Veltzke W; Strahlenklinik und Poliklinik, Freie Universitat Berlin,; Klinikum Rudolf Virchow.; With the incidence of AIDS being on the rise, diagnostic work-up of hepatobiliary disease in these patients is of increasing interest. 57 x-ray cholangiograms and computed tomographic studies of 13 AIDS-patients with clinical signs of cholangitis were reviewed. Nine patients had abnormal cholangiographic findings. Com
[Radioisomorphisms of sclerosing cholangitis]: Aktuelle Radiol. 1995 Jul;5(4):227-31. Unique Identifier : AIDSLINE MED/96024249; Knollmann FD; Maurer J; Adler A; Hintze RE; Grunewald T; Veltzke W; Lohmann R; Schedel H; Felix R; Strahlenklinik und Poliklinik, Freie Universitat Berlin Klinikum; Rudolf Virchow.; For differentiation of Primary Sclerosing Cholangitis (PSC) from AIDS-associated cholangitis (AAC), 95 CT or Cholangiography studies of 37 patients were reviewed and signs of biliary disease analysed. Only two each of PSC and AIDS-subjects were free from biliary lesions compatible with some kind of sclerosing cholangi
The third wave: HIV infection among heterosexuals in the United States and Europe [editorial]: Int J STD AIDS. 1995 Jul-Aug;6(4):227-32. Unique Identifier : AIDSLINE MED/96056089; Haverkos HW; Quinn TC
Surveillance of antibiotic resistance in Neisseria gonorrhoeae and implications for the therapy of gonorrhoea [editorial]: Int J STD AIDS. 1995 Jul-Aug;6(4):233-6. Unique Identifier : AIDSLINE MED/96056090; Tapsall JW
Management of protozoan infections in AIDS. The Jefferiss Wing Therapeutics and Protocols Group.: Int J STD AIDS. 1995 Jul-Aug;6(4):237-40. Unique Identifier : AIDSLINE MED/96056091; Tomlinson DR; Fisher M; Coker RJ; Department of Genitourinary Medicine, St. Mary's Hospital,; Paddington, London, UK.
Are you sure it's syphilis? A review of false positive serology.: Int J STD AIDS. 1995 Jul-Aug;6(4):241-8. Unique Identifier : AIDSLINE MED/96056092; Nandwani R; Evans DT; Department of GU/HIV Medicine, King's Healthcare, London, UK.; This article on false positive serological reactions for syphilis reviews the rapid developments which have taken place in the serodiagnosis of syphilis in recent years since the advent of the AIDS epidemic. An overview of non-specific and specific treponemal serological tests in relation to acute and chronic biologic
'Grey case'.: Int J STD AIDS. 1995 Jul-Aug;6(4):249-50. Unique Identifier : AIDSLINE MED/96056093; Sherrard J; Department of Genitourinary Medicine, Radcliffe Infirmary,; Oxford, UK.
Testing for HIV antibody: a comparison of two services offered in a genitourinary medicine clinic.: Int J STD AIDS. 1995 Jul-Aug;6(4):251-6. Unique Identifier : AIDSLINE MED/96056094; Rowen D; Carne CA; Sonnex C; Jones M; Maloney ME; Lefort W; Wreghitt TG; Department of Genito-Urinary Medicine, Royal South Hants; Hospital, Southampton, UK.; Rates of screening for sexually transmissible infections in patients using different services provided by a genitourinary medicine clinic for testing for HIV antibodies are presented. Those patients whose primary reason for attending the clinic was HIV antibody testing and used the same day result (SDR) service were s
Self-treatment of female external genital warts with 0.5% podophyllotoxin cream (Condyline) vs weekly applications of 20% podophyllin solution.: Int J STD AIDS. 1995 Jul-Aug;6(4):257-61. Unique Identifier : AIDSLINE MED/96056095; Hellberg D; Svarrer T; Nilsson S; Valentin J; Department of Obstetrics and Gynecology, Falun Hospital, Sweden.; Sixty women with genital warts were randomly allocated to treatment with either weekly application of 20% podophyllin solution or self-treatment with 0.5% podophyllotoxin cream twice daily for three days in weekly intervals. After a maximum of 4 treatment cycles a final assessment was carried out after 3 months. Prima
Cervical cytological screening in HIV-infected women in Dublin--a six-year review.: Int J STD AIDS. 1995 Jul-Aug;6(4):262-6. Unique Identifier : AIDSLINE MED/96056096; Murphy M; Pomeroy L; Tynan M; Murphy JF; Mulcahy FM; Department of Genitourinary Medicine, St James's Hospital,; Dublin, Ireland.; A retrospective study of the results of cervical cytological screening of HIV-infected women attending an inner city ambulatory HIV clinic over a 6-year period between 1987 and 1992 was carried out. During this time a total of 165 HIV-infected women attended for management of their HIV disease. The results of cervical
The activity of candidate virucidal agents, low pH and genital secretions against HIV-1 in vitro.: Int J STD AIDS. 1995 Jul-Aug;6(4):267-72. Unique Identifier : AIDSLINE MED/96056097; O'Connor TJ; Kinchington D; Kangro HO; Jeffries DJ; Department of Virology, Medical College, St Bartholomew's; Hospital, London, UK.; The effect of low pH, normally present in the female genital tract, on HIV viability was examined. HIV is more acid stable than previously reported with no substantial reduction in infectivity occurring until pH levels are reduced below 4.5. The virucidal activity of 3 topical spermicides and chlorhexidine was assesse
Sexually transmitted diseases and human immunodeficiency virus infection among women with genital infections in Burkina Faso.: Int J STD AIDS. 1995 Jul-Aug;6(4):273-7. Unique Identifier : AIDSLINE MED/96056098; Meda N; Ledru S; Fofana M; Lankoande S; Soula G; Bazie AJ; Chiron JP; Department of Obstetrics and Gynaecology, Centre Hospitalier; National Souro SANOU, Bobo-Dioulasso, Burkina Faso.; This study reports the prevalence of sexually transmitted diseases (STDs) among gynaecological outpatients presenting at the Bobo-Dioulasso Hospital ( Burkina Faso ) with genital infections and examines the factors associated with HIV infection in this population. Of 245 eligible no
Clinical features and serum beta 2-microglobulin levels in HIV-1 positive and negative Tanzanian patients with tuberculosis.: Int J STD AIDS. 1995 Jul-Aug;6(4):278-83. Unique Identifier : AIDSLINE MED/96056099; Kennedy N; Whitelaw FM; Gutmann J; Berger L; Uiso L; Ngowi FI; Gillespie SH; University Division of Communicable Diseases, Royal Free Hospital; School of Medicine, London, UK.; Serum beta 2-microglobulin (beta 2M) rises in the later stages of HIV disease and has therefore been used to monitor progression to AIDS. However, little work has been done on patients co-infected with HIV and tuberculosis. We studied clinical features and serum beta 2-M in 35 Tanzanian patients treated for pulmonary
HIV seroprevalence in healthy blood donors in northeastern Zaire.: Int J STD AIDS. 1995 Jul-Aug;6(4):284-6. Unique Identifier : AIDSLINE MED/96056100; Fischer PR; Toko RM; Department of Pediatrics, University of Utah, Salt Lake City; 84132, USA.; Despite high seroprevalence rates in some parts of Africa, there is notable variation in prevalence between population subgroups. To document changes and trends in HIV seroprevalence in northeastern Zaire , 1989 to 1992 blood donor data were reviewed. Overall, 2453 donors were test
Salmonella typhimurium empyema in an AIDS patient.: Int J STD AIDS. 1995 Jul-Aug;6(4):287-8. Unique Identifier : AIDSLINE MED/96056101; Colebunders R; Verstraeten T; Van den Abbeele K; Stappaert I; Van Meerbeeck J; Institute of Tropical Medicine, Antwerpen, Belgium.
Kaposi's sarcoma in the kidney.: Int J STD AIDS. 1995 Jul-Aug;6(4):289-90. Unique Identifier : AIDSLINE MED/96056102; Pollok RC; Francis N; Cliff S; Nelson N; Gazzard B; Department of HIV/GUM, St Stephen's Clinic, Chelsea & Westminster; Hospital, London, UK.
Routine screening for Chlamydia trachomatis urethral infections in men [letter; comment]: Int J STD AIDS. 1995 Jul-Aug;6(4):297; discussion 298. Unique Identifier : AIDSLINE MED/96056103; Taylor-Robinson D
Chlamydial urethritis in heterosexual men attending a genitourinary medicine clinic: prevalence, symptoms, condom usage and partner change [letter; comment]: Int J STD AIDS. 1995 Jul-Aug;6(4):298; discussion 299. Unique Identifier : AIDSLINE MED/96056104; Wardropper AG; Watson PG; Sankar KN
Antenatal attenders and HIV testing [letter; comment]: Int J STD AIDS. 1995 Jul-Aug;6(4):299; discussion 300. Unique Identifier : AIDSLINE MED/96056105; Kell P; Desmond N
Dose-response and trend analysis in epidemiology: alternatives to categorical analysis [see comments]: Epidemiology. 1995 Jul;6(4):356-65. Unique Identifier : AIDSLINE MED/96039979; Greenland S; Department of Epidemiology, UCLA School of Public Health; 90095-1772, USA.; Standard categorical analysis is based on an unrealistic model for dose-response and trends and does not make efficient use of within-category information. This paper describes two classes of simple alternatives that can be implemented with any regression software: fractional polynomial regression and spline regressio
Is the human immunodeficiency virus-related Kaposi's sarcoma epidemic coming to an end? Insights from the Tricontinental Seroconverter Study.: Epidemiology. 1995 Jul;6(4):382-6. Unique Identifier : AIDSLINE MED/96039983; Veugelers PJ; Strathdee SA; Moss AR; Page KA; Tindall B; Schechter MT; Coutinho RA; van Griensven GJ; Municpal Health Service, Department of Public Health, Amsterdam,; The Netherlands.; A decline in the proportion of Kaposi s sarcoma among AIDS cases since the 1980s has been attributed to changes in sexual behavior among homosexual men and a decreasing exposure to a hypothesized Kaposi s sarcoma cofactor. Recent studies have shown that the incidence rate of Kaposi s sarcoma has remained relatively st
Quantification of feline immunodeficiency virus (FIV) proviral DNA in peripheral blood mononuclear cells of cats infected with Japanese strains of FIV.: J Vet Med Sci. 1995 Jun;57(3):487-92. Unique Identifier : AIDSLINE MED/96031673; Inoshima Y; Tomonaga K; Ikeda Y; Miyazawa T; Mikami T; Department of Veterinary Microbiology, Faculty of Agriculture,; University of Tokyo, Japan.; The polymerase chain reaction (PCR) method was applied for measurement of the proviral DNA copy number of feline immunodeficiency virus (FIV) in peripheral blood mononuclear cells (PBMC) of cats experimentally and naturally infected with FIV. In experimentally infected cats except one cat infected with the Petaluma st
Injection drug use and human immunodeficiency virus infection.: Clin Infect Dis. 1995 Jun;20(6):1467-79. Unique Identifier : AIDSLINE MED/96034936; Alcabes P; Friedland G; Yale University AIDS Program, New Haven, Connecticut 06510, USA.; In this paper we discuss the epidemiology and natural history of human immunodeficiency virus (HIV) infection in users of injection drugs. Use of injection drugs plays a central role in the HIV infection/AIDS epidemic in the United States , Europe, and many parts of the developing world
Human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis in Sao Paulo, Brazil.: Clin Infect Dis. 1995 Jun;20(6):1540-2. Unique Identifier : AIDSLINE MED/96034948; Domingues RB; Muniz MR; Pinho JR; Bassit L; Jorge ML; Alquezar AS; Marchiori PE; Chamone DF; Scaff M; Department of Neurology, University of Sao Paulo School of; Medicine, Brazil.; We conducted a prospective clinical and epidemiologic evaluation of 45 cases of human T lymphotropic virus type I (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Sao Paulo, Brazil . All enrolled patients had progressive chronic myelopathy and high titers of
Clarithromycin-induced mania in two patients with AIDS.: Clin Infect Dis. 1995 Jun;20(6):1563-4. Unique Identifier : AIDSLINE MED/96034955; Nightingale SD; Koster FT; Mertz GJ; Loss SD; University of Texas Southwestern Medical Center at Dallas, USA.; Acute psychosis was observed in two patients with AIDS who were treated with clarithromycin for disseminated Mycobacterium avium complex infection. The psychosis resolved when treatment with clarithromycin was discontinued and recurred when it was resumed. An adverse response to clarithromycin therapy is a rare but cu
Mycobacterium genavense infection in a patient with AIDS who was successfully treated with clarithromycin [letter]: Clin Infect Dis. 1995 Jun;20(6):1565-6. Unique Identifier : AIDSLINE MED/96034957; Matsiota-Bernard P; Thierry D; De Truchis P; Saillour M; Paraire F; Guesdon JL; Nauciel C
Pentamidine concentrations in a mother with AIDS and in her neonate [letter]: Clin Infect Dis. 1995 Jun;20(6):1569-70. Unique Identifier : AIDSLINE MED/96034960; Schwebke K; Fletcher CV; Acosta EP; Henry K
Myasthenia gravis and systemic lupus erythematosus in association with human immunodeficiency virus infection [letter]: Clin Infect Dis. 1995 Jun;20(6):1577-8. Unique Identifier : AIDSLINE MED/96034967; Maradona JA; Carton JA; Asensi V
Appendicitis due to Mycobacterium avium complex in an adolescent infected with the human immunodeficiency virus [letter]: Clin Infect Dis. 1995 Jun;20(6):1579-80. Unique Identifier : AIDSLINE MED/96034969; Livingston RA; Siberry GK; Paidas CN; Eiden JJ
Incidence and clinical relevance of anaerobic bacterial infections in patients with AIDS at an infectious diseases institute.: Clin Infect Dis. 1995 Jun;20 Suppl 2:S212-3. Unique Identifier : AIDSLINE MED/96023533; Coronado O; Mastroianni A; Manfredi R; Nanetti A; Chiodo F; Istituto Malattie Infettive, Policlinico Sant'Orsola, Universita; di Bologna, Italy.
[Alpha tumor necrosis factor in central nervous system disease associated with HIV infection]: An Med Interna. 1995 Jun;12(6):263-6. Unique Identifier : AIDSLINE MED/96005176; Calvo Manuel E; Arranz Garcia F; Sanchez-Portocarrero J; Roca Arbones V; Puente M; Elias Arcalis A; Perez-Cecilia E; Nieto Sanchez A; Espinos Perez D; Servicio de Medicina Interna I, Hospital Universitario San; Carlos, Facultad de Medicina, Universidad Complutense, Madrid.; The aim of the present study is to evaluate the relationship between the alpha tumor necrosis factor (TNF-alpha), interleukin 1 beta (IL-1 beta) and the neurological disease associated to the HIV-1 infection and different neurological manifestations (15 infections of the CNS and 11 AIDS-
[HTLV-I AND HTLV-II in Spain]: An Med Interna. 1995 Jun;12(6):299-306. Unique Identifier : AIDSLINE MED/96005186; Up to October 1994, twenty-four HTLV-I and 113 HTLV-II infected persons have been identified in Spain . A third of HTLV-I carriers were immigrants coming from endemic regions. In contrast, most HTLV-II-infected persons were Spanish native drug users. Four cases of HTLV-I-associated m
[Opinion of asymptomatic HIV-positive patients about their primary care physicians]: Aten Primaria. 1995 Sep 15;16(4):215-9. Unique Identifier : AIDSLINE MED/96016789; Belda Ibanez J; Gil Guillen V; Fernandez Garcia E; Trullen Gas P; Martinez Quintero R; Prado Saez A; Orozco Beltran D; Centro de Informacion y Prevencion del SIDA, Alicante.; OBJECTIVE. To find the opinion of asymptomatic HIV+patients about their Primary Care doctors. DESIGN. A descriptive, crossover study with an 11-item questionnaire, filled in by the patient him/herself anonymously and analysing: communication of being seropositive, frequency of attendance, confidence in the doctor and
[Therapeutic relations between health professionals and patients. Experience of a work group]: Aten Primaria. 1995 Sep 15;16(4):221-8. Unique Identifier : AIDSLINE MED/96016790; Ramirez Hidalgo A; Mausbach H; de Miguel Blanco C; Ros Rahola R; Centre d'Orientacio i Planificacio Familiar la Sagrera,; Barcelona.
Use of historical marker data for assessing treatment effects in phase I/II trials when subject selection is determined by baseline marker level.: Biometrics. 1995 Sep;51(3):1053-63. Unique Identifier : AIDSLINE MED/96054346; Lin HM; Hughes MD; Department of Biostatistics, Harvard School of Public Health,; Boston, Massachusetts 02115, USA.; Although the primary focus of Phase I clinical trials is to assess clinical pharmacology and possible toxicities, any information on the potential effect of treatment would be useful in helping to determine priorities between treatments for further study. We consider the scenario where data are routinely collected on
Empirical estimation of a distribution function with truncated and doubly interval-censored data and its application to AIDS studies.: Biometrics. 1995 Sep;51(3):1096-104. Unique Identifier : AIDSLINE MED/96054349; Sun J; Department of Statistics and Actuarial Science, University of; Waterloo, Ontario Canada.; In this paper we discuss the non-parametric estimation of a distribution function based on incomplete data for which the measurement origin of a survival time or the date of enrollment in a study is known only to belong to an interval. Also the survival time of interest itself is observed from a truncated distribution
Hazard function estimation using B-splines.: Biometrics. 1995 Sep;51(3):874-87. Unique Identifier : AIDSLINE MED/96054334; Rosenberg PS; National Cancer Institute, Epidemiologic Methods Section,; Rockville, Maryland 20852, USA.; A flexible parametric procedure is given to model the hazard function as a linear combination of cubic B-splines and to obtain maximum likelihood estimates from censored survival data. The approach yields smooth estimates of the hazard and survivorship functions that are intermediate in structure between strongly para
Specific disulfide formation in the oxidation of HIV-1 zinc finger protein nucleocapsid p7.: Chem Res Toxicol. 1995 Jun;8(4):586-90. Unique Identifier : AIDSLINE MED/96015469; Yu X; Hathout Y; Fenselau C; Sowder RC 2nd; Henderson LE; Rice WG; Mendeleyev J; Kun E; Department of Chemistry and Biochemistry, University of Maryland; Baltimore County 21228-5398, USA.; In vitro oxidation of the HIV-1 nucleocapsid protein p7 by the C-nitroso compound 3-nitrosobenzamide (NOBA) has been investigated. When reconstituted p7 was incubated with NOBA, three disulfide bonds were formed per molecule of p7, Cys 15-Cys 18, Cys 28-Cys 36, and Cys 39-Cys 49. These were identified using the proteo
Absorption of new HIV-1 protease inhibitor, KNI-272, after intraduodenal and intragastric administrations to rats: effect of solvent.: Biopharm Drug Dispos. 1995 May;16(4):269-77. Unique Identifier : AIDSLINE MED/96031392; Sugahara M; Kiriyama A; Hamada Y; Kiso Y; Takada K; Department of Pharmaceutics and Pharmacokinetics, Kyoto; Pharmaceutical University, Japan.; KNI-272 is a tripeptide drug that has a strong pharmacological potential for treating human immunodeficiency virus type 1 (HIV-1). We have already reported the pharmacokinetic characteristics of KNI-272 after intravenous and intraduodenal (ID) administrations to rats. In this study, KNI-272 was administered to rats as
Cell death in health and disease: the biology and regulation of apoptosis.: Semin Cancer Biol. 1995 Feb;6(1):3-16. Unique Identifier : AIDSLINE MED/96037771; Bellamy CO; Malcomson RD; Harrison DJ; Wyllie AH; Department of Pathology, University Medical School, Edinburgh,; UK.; Apoptosis is a morphologically stereotyped form of cell death, prevalent in multicellular organisms, by which single cells are deleted from the midst of living tissues. Recognition of the cellular corpses and their removal by phagocytosis occurs without disturbance to tissue architecture or function and without initia
Mycobacteria in HIV-infected patients in Buenos Aires.: Tuber Lung Dis. 1995 Jun;76(3):185-9. Unique Identifier : AIDSLINE MED/96014883; Di Lonardo M; Isola NC; Ambroggi M; Rybko A; Poggi S; Dr A. Cetrangolo Bacteriology Laboratory, F. J. Muniz Hospital,; Buenos Aires, Argentina.; SETTING: F. J. Muniz Hospital and Department of Phthisiopneumonology, in Buenos Aires. OBJECTIVE: To analyze bacteriological findings concerning tuberculosis and other mycobacteriosis, in association with HIV infection and AIDS. DESIGN: From June 1985 to December 1991, 2521 samples from 1259 HIV-seropositive and AIDS
The increase in tuberculosis notifications in England and Wales since 1987.: Tuber Lung Dis. 1995 Jun;76(3):196-200. Unique Identifier : AIDSLINE MED/96014885; Doherty MJ; Spence DP; Davies PD; Aintree Chest Centre, Fazakerley Hospital, Liverpool, UK.; SETTING: A retrospective study of tuberculosis notifications in England and Wales published by the Office of Population Censuses and Surveys. OBJECTIVE: To analyse the rise in tuberculosis notifications in England and Wales by different sub groups over the time period 1982-91. DESIGN: The average annual percentage cha
A pilot study of antituberculosis combinations comparing rifabutin with rifampicin in the treatment of HIV-1 associated tuberculosis. A single-blind randomized evaluation in Ugandan patients with HIV-1 infection and pulmonary tuberculosis.: Tuber Lung Dis. 1995 Jun;76(3):210-8. Unique Identifier : AIDSLINE MED/96014888; Schwander S; Rusch-Gerdes S; Mateega A; Lutalo T; Tugume S; Kityo C; Rubaramira R; Mugyenyi P; Okwera A; Mugerwa R; et al; Clinical Department Bernhard Nocht Institute for Tropical; Medicine, Hamburg, Germany.; SETTING: This pilot study was conducted at the Joint Clinical Research Centre (JCRC) in Kampala, Uganda , where tuberculosis (TB) is an epidemic health problem aggravated by the HIV-1 pandemic. OBJECTIVE: To evaluate the feasibility of a larger phase III trial utilizing rifabutin as
Preliminary evaluation of a Mycobacterium tuberculosis lipooligosaccharide (LOS) antigen in the serological diagnosis of tuberculosis in HIV seropositive and seronegative patients.: Tuber Lung Dis. 1995 Jun;76(3):234-9. Unique Identifier : AIDSLINE MED/96014892; Daleine G; Lagrange PH; Service de Microbiologie, Hopital Saint-Louis, Paris, France.; OBJECTIVE: To assess the value of detection of specific IgG or IgM antibodies against three polar glycolipids of Mycobacterium tuberculosis in HIV seropositive and seronegative patients with documented active tuberculosis. DESIGN: Using an ELISA test, concentrations of IgM and IgG antibodies against phenolic glycolipi
A national computer-based surveillance system for tuberculosis notification in Singapore.: Tuber Lung Dis. 1995 Jun;76(3):264-70. Unique Identifier : AIDSLINE MED/96014897; Snodgrass I; Chew SK; Communicable Disease Centre, Ministry of Health, Singapore.; SETTING: The notification rate of tuberculosis (TB) among residents in Singapore has been declining at a mean rate of 5.6% per annum, from 307 cases per 100,000 population in 1960 to 54 cases per 100,000 population in 1992. A National TB Notification Registry was set up in 1958
Autopsy findings of Addison's disease caused by systemic cytomegalovirus infection in a patient with acquired immunodeficiency syndrome.: Intern Med. 1995 Jun;34(6):533-6. Unique Identifier : AIDSLINE MED/96012382; Takasawa A; Morimoto I; Wake A; Haratake J; Fujii K; Okada Y; Oda S; Hashimoto H; Eto S; First Department of Internal Medicine, University of Occupational; and Environmental Health, Fukuoka.; We previously reported a case of Addison s disease associated with acquired immunodeficiency syndrome (AIDS) (Endocr J, 41:13, 1994). A 46-year-old man with hemophilia B and AIDS was diagnosed as Addison s disease. The positive cytomegalovirus (
Targeting HIV with liposome-encapsulated antivirals [editorial]: Int J Med Microbiol Virol Parasitol Infect Dis. 1995 Apr;282(3):225-31. Unique Identifier : AIDSLINE MED/96002166; Desormeaux A; Bergeron MG
[The clinical and immunological correlations between the p24 antigenemia levels and those of anti-p24 antibodies in HIV-seropositive children]: Bacteriol Virusol Parazitol Epidemiol. 1995 Apr-Jun;40(2):141-4. Unique Identifier : AIDSLINE MED/96029120; Apetrei C; Buzdugan I; Mitroi I; Duca M; Laboratorul de Virologie, U.M.F. Iasi.; The influence of HIV I p24 antigen immune complexing with anti-p24 antibodies of the assessment of their respective levels in HIV-positive sera was studied. ELISA tests were used for evaluating anti-p24 and p24 antigenemia, with or without acid dissociation. We have observed that: 1. p24 antigenemia usually coexisted
[The resistance to antibiotics and chemotherapeutic agents of Shigella strains isolated from HIV-seropositive children]: Bacteriol Virusol Parazitol Epidemiol. 1995 Apr-Jun;40(2):145-8. Unique Identifier : AIDSLINE MED/96029121; Sfartz S; Dragomir C; Negut E; Zugun F; Macovei O; Jica S; Clinica de Puericultura, U.M.F. Iasi.
[Purulent meningitis with nonserotypable Haemophilus influenzae in infants and adults]: Bacteriol Virusol Parazitol Epidemiol. 1995 Apr-Jun;40(2):149-51. Unique Identifier : AIDSLINE MED/96029122; Mihancea N; Dorobat O; Homos M; Rasnoveanu D; Strutu I; Strutu H; Burlacu M; Institutul Cantacuzino, Bucuresti.
[Glycoprotein D (5-23) specific Th2-T-cell line induces HSV-1 keratitis]: Ophthalmologe. 1995 Aug;92(4):484-91. Unique Identifier : AIDSLINE MED/96056406; Heiligenhaus A; Jayaraman S; Soukiasian S; Dorf M; Foster CS; Hilles Immunology Laboratory, Massachusetts Eye and Ear; Infirmary, Harvard Medical School, Boston, USA.; BALB/c inbred Igh-1-disparate mice exhibit different susceptibility to the development of HSV-1 stromal keratitis (HSK), which may be due to the differential immune regulation. CD4+ T lymphocytes may be critical for the disease induction. A T-cell line (CD4+, T-cell receptor V beta 8+, interleukin-4+) specific for the
[Effect of Astragalus membranaceus on T-lymphocyte subsets in patients with viral myocarditis]: Chung Kuo Chung Hsi I Chieh Ho Tsa Chih. 1995 Jun;15(6):328-30. Unique Identifier : AIDSLINE MED/96022960; Huang ZQ; Qin NP; Ye W; Zhejiang provincial TCM Hospital, Hangzhou.; The efficacy of Astragalus membranaceus (AM) oral liquor combined with routine therapy and routine therapy alone on T-lymphocyte subsets of peripheral blood in viral myocarditis patients have been studied. The results showed that the T-lymphocyte subsets profile and OKT4/OKT8 ratio of peripheral blood were significant
Interleukin-12.: Int Arch Allergy Immunol. 1995 Oct;108(2):103-12. Unique Identifier : AIDSLINE MED/96021091; Germann T; Rude E; Institute for Immunology, Mainz, Germany.; Interleukin (IL)-12 was originally identified as a factor produced by human Epstein-Barr virus-transformed B cell lines. It was detected by one group as cytotoxic lymphocyte maturation factor, a cytokine that synergized with IL-2 in the induction of lymphokine-activate
Analysis of bronchoalveolar lavage cells in chronic eosinophilic pneumonia before and during corticosteroid therapy.: Int Arch Allergy Immunol. 1995;108 Suppl 1:2-5. Unique Identifier : AIDSLINE MED/96011675; Takahashi H; Arakawa Y; Oki K; Sugita H; Sakamoto S; Kawabata Y; Fukujuji Hospital, Japan Anti-TB Association, Tokyo.; Bronchoalveolar lavage was performed in patients with chronic eosinophilic pneumonia of unknown origin diagnosed histopathologically, and the alveolar fluid cells were investigated before and during corticosteroid therapy. The counts of eosinophils in bronchoalveolar lavage fluid decreased markedly during steroid ther
HIV virus does cause AIDS, research shows [news]: BMJ. 1995 Sep 9;311(7006):645. Unique Identifier : AIDSLINE MED/96035790; Kingman S
South Africa steps up fight against HIV and AIDS [news]: BMJ. 1995 Sep 9;311(7006):645. Unique Identifier : AIDSLINE MED/96035789; Sidley P
Late diagnosis of HIV infection in children is common and devastating [letter; comment]: BMJ. 1995 Sep 16;311(7007):747. Unique Identifier : AIDSLINE MED/96009940; Barrett G; Victor CR
Pelvocalyceal thickening in HIV-associated nephropathy.: Abdom Imaging. 1995 Jul-Aug;20(4):371-5. Unique Identifier : AIDSLINE MED/96045046; Wachsberg RH; Obolevich AT; Lasker N; Department of Radiology, University Hospital, Newark, NJ 07103,; USA.; BACKGROUND: Previously reported causes of renal pelvocalyceal thickening (PCT) include infection, acute tubular necrosis and obstruction. This study was performed to evaluate the significance of PCT noted sonographically in patients with hyperechoic native kidneys. METHODS: We evaluated sonograms of 178 consecutive pa
Self-reports of HIV risk behavior by injecting drug users: are they reliable?: Addiction. 1995 Aug;90(8):1097-104. Unique Identifier : AIDSLINE MED/96024235; Goldstein MF; Friedman SR; Neaigus A; Jose B; Ildefonso G; Curtis R; National Development and Research Institutes, Inc., New York, New; York 10013, USA.; While most studies of AIDS risk behavior rely on self-reports, few studies have assessed the reliability of these reports. The present study examines self-reports of drug-related and sexual risk behavior among pairs of injecting drug users (IDUs) recruited from the streets in New York City. Since both members of the p
Prospective effects of perceived risk of developing HIV/AIDS on risk behaviors among injection drug users in Puerto Rico.: Addiction. 1995 Aug;90(8):1105-11. Unique Identifier : AIDSLINE MED/96024236; Robles RR; Cancel LI; Colon HM; Matos TD; Freeman DH; Sahai H; Research Institute, Mental Health and Anti Addiction Services; Administration, San Juan, Puerto Rico.; The relationship between perceived risk of developing AIDS and subsequent behavioral risk status is estimated for 1740 Puerto Rican injection drug users (IDUs). Prospective behavioral effects were examined comparing data collected at two intervals approximately 6 months apart. We estimated the association between perc
Alterations in cell-cell communication in human papillomavirus type 16 (HPV16) transformed rat myoblasts.: Cell Mol Biol (Noisy-le-grand). 1995 Jun;41(4):481-98. Unique Identifier : AIDSLINE MED/96057185; Ennaji MM; Schwartz JL; Mealing G; Belbaraka L; Parker C; Parentaux M; Jouishomme H; Arella M; Whitfield JF; Phipps J; National Research Council of Canada, Steacie Institute for; Molecular Sciences, Ottawa, Ontario.; A reduction of gap-junctional intercellular communication (GJIC) often accompanies neoplastic transformation. The present work demonstrates that transformation by the oncogenic human DNA virus, human papilloma virus 16(HPV16), also reduces GJIC between L6 rat myoblasts. HPVs are associated with anogenital cancers, the
HTLV-I positive progressive spastic paraparesis (TSP) associated with a lymphoid disorder in three Chilean patients.: Leuk Lymphoma. 1995 May;17(5-6):459-64. Unique Identifier : AIDSLINE MED/96037825; Cartier L; Castillo JL; Cabrera ME; Araya F; Matutes E; Ford AM; Greaves MF; Department of Neurology, Faculty of Medicine, University of; Chile, Santiago.; We describe the clinical and laboratory features in three Caucasian Chilean patients with tropical spastic paraparesis (TSP) associated with/or preceded by a lymphoproliferative disorder involving cutaneous lesions and localised lymphadenopathy. The neurological symptoms and signs were characteristic of TSP and CSF ex
Detection of infectious disease agents in tissue by immunocytochemistry.: Braz J Med Biol Res. 1994 Dec;27(12):2803-20. Unique Identifier : AIDSLINE MED/96032055; Bacchi CE; Gown AM; Bacchi MM; Departamento de Patologia, Faculdade de Medicina, Universidade; Estadual Paulista, Botucatu, SP, Brasil.; 1. Immunocytochemical procedures have played an increasingly larger role in the identification of infectious disease agents in tissue sections owing to the increased availability and specificity of antibody reagents, the great sensitivity of the methods, and the relative facility with which the studies are performed.
Novel assay system favorable for the study of cell-to-cell transmission of HIV-1 and its application to the evaluation of anti-HIV drugs.: Biol Pharm Bull. 1995 Jun;18(6):920-2. Unique Identifier : AIDSLINE MED/96044634; Inouye Y; Kanamori T; Fujimoto Y; Sugiyama M; Yoshida T; Institute of Pharmaceutical Sciences, Hiroshima University School; of Medicine, Japan.; The cell-to-cell transmission of human immunodeficiency virus type 1 (HIV-1) was studied using MOLT-4 cells chronically infected with a variant strain of HIV-1SF-2 (MOLT-4/HIV-1SF-2H) and CD4+ human lymphoid MT-4 cells. MOLT-4/HIV-1SF-2H cells produced less than 1 TCID50 infectious particles per day as determined by t
Evaluating the quality of life associated with rifabutin prophylaxis for Mycobacterium avium complex in persons with AIDS: combining Q-TWiST and multiattribute utility techniques.: Qual Life Res. 1995 Aug;4(4):309-18. Unique Identifier : AIDSLINE MED/96045252; Revicki DA; Simpson KN; Wu AW; LaVallee RL; Medical Technology Assessment and Policy Research Program,; Battelle Centers for Public Health Research and Evaluation,; Arlington, VA 22201, USA.; Our objective was to evaluate the effect of rifabutin prophylaxis in patients with AIDS and CD4 counts of less than 200 per cubic millimetre using a combination of Q-TWiST (quality-adjusted time without symptoms and toxicity) and multiattribute health utility assessment. The design consisted of a secondary analysis of
Microglia: intrinsic immuneffector cell of the brain.: Brain Res Brain Res Rev. 1995 Mar;20(3):269-87. Unique Identifier : AIDSLINE MED/96031752; Gehrmann J; Matsumoto Y; Kreutzberg GW; Department of Pathology, University Hospital, Zurich,; Switzerland.; Microglia form a regularly spaced network of resident glial cells throughout the central nervous system (CNS). They are morphologically, immunophenotypically and functionally related to cells of the monocyte/macrophage lineage. In the ultimate vicinity of the blood-brain barrier two specialized subsets of macrophages/
Outbreak of hospital acquired multidrug resistant tuberculosis.: Commun Dis Rep CDR Wkly. 1995 Aug 25;5(34):161. Unique Identifier : AIDSLINE MED/96040915
Kaposi's sarcoma with elephantiasis associated with AIDS.: J Wound Ostomy Continence Nurs. 1995 Sep;22(5):223-6. Unique Identifier : AIDSLINE MED/96011099; Harbit M; Srinivas PB; Nurses in many parts of the United States have limited experience in caring for patients with Kaposi s sarcoma. The severity of the disease can range from a few lesions to extensive cases with fungating, encrusted wounds. This case study describes the wound management of a 43-year-old
How have Zambian businesses reacted to the HIV epidemic?: Occup Environ Med. 1995 Sep;52(9):565-9. Unique Identifier : AIDSLINE MED/96030731; Baggaley R; Godfrey-Faussett P; Msiska R; Chilangwa D; Chitu E; Porter J; Kelly M; Kara Counselling and Training Trust, Lusaka, Zambia.; OBJECTIVES--To evaluate the impact of HIV on businesses in Zambia and to assess attitudes towards HIV and HIV education in the workplace. METHODS--The personnel managers of 33 companies with a total workforce of 10,204 in Lusaka and in towns in the Copperbelt were visited by two me
Survival trends in adolescents with human immunodeficiency virus infection.: Arch Pediatr Adolesc Med. 1995 Oct;149(10):1093-6. Unique Identifier : AIDSLINE MED/96003536; Remafedi G; Lauer T; Department of Pediatrics, University of Minnesota Hospital and; Clinics, Minneapolis, USA.; OBJECTIVE: To examine trends in survival and death in nonhemophiliac adolescents with human immunodeficiency virus (HIV) infection. DESIGN: Case series. SUBJECTS: All 117 HIV-seropositive adolescents (age range, 13 to 21 years) without hemophilia whose cases were reported through December 1992. SETTING: A state with m
[Early hematological consequences in infants born to HIV seropositive mothers treated with zidovudine during pregnancy (letter)]: Arch Pediatr. 1995 Aug;2(8):800-1. Unique Identifier : AIDSLINE MED/96014131; Tricoire J; Claeyssens S; Berrebi A; Izopet J; Rolland M
Simple, rapid and sensitive high-performance liquid chromatographic determination of delavirdine and its N-desisopropyl metabolite in human plasma.: J Chromatogr B Biomed Appl. 1995 Jun 9;668(1):99-106. Unique Identifier : AIDSLINE MED/96035206; Staton BA; Johnson MG; Friis JM; Adams WJ; Biofluids Analytical Laboratory, Upjohn Co., Kalamazoo, MI 49001,; USA.; A method for the determination of a bisheteroarylpiperazine, non-nucleoside HIV-1 reverse transcriptase inhibitor, delavirdine , and its N-desisopropyl metabolite in human plasma, is described. Samples were deproteinized by addition of two parts of a s
Candida dubliniensis sp. nov.: phenotypic and molecular characterization of a novel species associated with oral candidosis in HIV-infected individuals.: Microbiology. 1995 Jul;141 ( Pt 7):1507-21. Unique Identifier : AIDSLINE GENBANK/Z48346; Sullivan DJ; Westerneng TJ; Haynes KA; Bennett DE; Coleman DC; University of Dublin, School of Dental Science, Department of; Oral Medicine and Pathology, Trinity College, Republic of; Ireland.; Atypical oral Candida isolates were recovered from 60 HIV-infected and three HIV-negative individuals. These organisms were germ-tube-positive and produced abundant chlamydospores which were frequently arranged in triplets or in contiguous pairs. They belonged to C. albicans serotype A and had atypical carbohydrate as
[AIDS and nursing: attitudes towards personality traits in the context of hospital care]: Rev Lat Am Enfermagem. 1994 Jan;2(1):41-56. Unique Identifier : AIDSLINE MED/96024515; Figueiredo MA; de Morais KC; The objective of the present study was to determine possible relations between attitudes towards some aspects of facing AIDS and personality traits in nursing personnel for later elaboration of a program of guidance and follow-up of professionals who treat the disease. On the basis of the attitude scales constructed b
Emerging pathogens [editorial]: Curr Opin Neurol. 1995 Jun;8(3):161-3. Unique Identifier : AIDSLINE MED/96023830; Gonzalez-Scarano F
Neurologic complications of Bartonella henselae infection.: Curr Opin Neurol. 1995 Jun;8(3):164-9. Unique Identifier : AIDSLINE MED/96023831; Marra CM; Department of Medicine, University of Washington School of; Medicine, Seattle, USA.; Bartonella henselae can cause cat scratch disease and bacillary angiomatosis , a multisystem disorder seen primarily in patients with the acquired immunodeficiency syndrome. Both of these diseases are associated with neurologic complications, particularly encephalopathy. B. he
Neurologic opportunistic infections.: Curr Opin Neurol. 1995 Jun;8(3):175-8. Unique Identifier : AIDSLINE MED/96023833; Clifford DB; Department of Neurology, Washington University School of; Medicine, St Louis, Missouri, USA.; Three common opportunistic infections in patients with the human immunodeficiency virus are being more accurately diagnosed and effectively treated as a result of recent advances. Toxoplasmosis may be prevented in some cases, and can be recognized and treated noninvasively in most cases. Cryptococcal therapy has been
Human T lymphotropic virus, type-I myelopathy: an immunopathologically mediated chronic progressive disease of the central nervous system.: Curr Opin Neurol. 1995 Jun;8(3):179-83. Unique Identifier : AIDSLINE MED/96023834; Jacobson S; Viral Immunology Section, National Institute of Neurological; Disorders and Stroke, National Institutes of Health, Bethesda,; Maryland, USA.; The human T lymphotropic virus, type-I is associated with a slowly progressive neurologic disorder termed human T lymphotropic virus, type-I associated myelopathy/tropical spastic paraparesis. Considerable information on the pathology, epidemiology, virology, and immunology is known about this disorder and will serve
Progressive multifocal leukoencephalopathy: clinical and laboratory observations on a viral induced demyelinating disease in the immunodeficient patient.: Curr Opin Neurol. 1995 Jun;8(3):184-90. Unique Identifier : AIDSLINE MED/96023835; Major EO; Ault GS; Laboratory of Molecular Medicine and Neuroscience, National; Institute of Neurological Disorders and Stroke, Bethesda,; Maryland, USA.; Progressive multifocal leukoencephalopathy is a viral-induced demyelinating disease of the central nervous system usually occurring in the immunocompromised individual. The incidence of progressive multifocal leukoencephalopathy has risen sharply over the past decade because of widespread human immunodeficiency virus
Selective causes of fever in adult human immunodeficiency virus-infected patients relative to CD4+ cell counts.: Arch Fam Med. 1995 Oct;4(10):879-84. Unique Identifier : AIDSLINE MED/96011557; Czachor JS; Gleckman RA; Division of Infectious Diseases, Wright State University School; of Medicine, Miami Valley Hospital, Dayton, Ohio, USA.; Fever is a common finding in the patient who is infected with the human immunodeficiency virus. As immunocompetence wanes, febrile episodes become more common, although the virus itself is seldom the cause of the fever. A thorough evaluation, based on the history and physical findings and directed by the level of immu
IgE antibodies against snake venoms.: J Investig Allergol Clin Immunol. 1995 Jan-Feb;5(1):31-4. Unique Identifier : AIDSLINE MED/96053417; Alonso A; Scavini LM; Marino GA; Rodriguez SM; Department of Allergy and Immunology, Clinical Hospital, Buenos; Aires, Argentina.; A similar event was detected in the clinical records of a small group of atopic patients living in the northern provinces of Argentina , i.e., they were bitten by a snake of the Bothrops species (or yarara) during their rural activities (woodcutters, cattle-drivers and farmers).
Laboratory empiricism, clinical design, and social value. The rough road toward vaccine development.: Pharm Biotechnol. 1995;6:135-9. Unique Identifier : AIDSLINE MED/96057684; Francis DP; Genentech, Inc., South San Francisco, California 94080, USA.
MF59. Design and evaluation of a safe and potent adjuvant for human vaccines.: Pharm Biotechnol. 1995;6:277-96. Unique Identifier : AIDSLINE MED/96057688; Ott G; Barchfeld GL; Chernoff D; Radhakrishnan R; van Hoogevest P; Van Nest G; Chiron Corporation, Emeryville, California 94608, USA.; MF59 is a safe, practical, and potent adjuvant for use with human vaccines. The formulation is easily manufactured, may be sterilized by filtration, and is both compatible and efficacious with all antigens tested to date. MF59 has been shown to be a potent stimulator of cellular and humoral responses to subunit antige
Nanoparticles as adjuvants for vaccines.: Pharm Biotechnol. 1995;6:463-72. Unique Identifier : AIDSLINE MED/96057697; Kreuter J; Institute for Pharmaceutical Technology, Johann Wolfgang Goethe; University, Frankfurt am Main, Germany.; PMMA nanoparticle adjuvants can be manufactured in a physicochemically reproducible manner. Their particle size can be controlled within narrow limits. Immunogens may be either incorporated or adsorbed to these nanoparticles. PMMA nanoparticles induced significantly higher and more prolonged antibody responses against
Design of experimental synthetic peptide immunogens for prevention of HIV-1 and HTLV-I retroviral infections.: Pharm Biotechnol. 1995;6:821-45. Unique Identifier : AIDSLINE MED/96057715; Hart MK; Palker TJ; Haynes BF; Division of Virology, U.S. Army Medical Research Institute for; Infectious Diseases, Fort Detrick, Frederick, Maryland 21702,; USA.
Clinical considerations in vaccine trials with special reference to candidate HIV vaccines.: Pharm Biotechnol. 1995;6:97-134. Unique Identifier : AIDSLINE MED/96057683; Fast PE; Sawyer LA; Wescott SL; Vaccine and Prevention Research Program, National Institute of; Allergy and Infectious Diseases, National Institutes of Health,; Bethesda, Maryland 20892, USA.
Monocyte responsiveness and a T-cell subtype predict the effects induced by cotton dust exposure.: Am J Respir Crit Care Med. 1995 Oct;152(4 Pt 1):1215-20. Unique Identifier : AIDSLINE MED/96023195; Beijer L; Jacobs RR; Boehlecke B; Andersson B; Rylander R; Department of Environmental Medicine, Goteborg University,; Sweden.; The aim of the study was to evaluate whether peripheral cellular parameters could predict susceptibility to decreased lung function and associated symptoms, in response to a single exposure to cotton dust. Previously nonexposed subjects (n = 42) inhaled an aerosol of cotton dust in a model cardroom during a period of
Community-acquired pneumonia: impact of immune status.: Am J Respir Crit Care Med. 1995 Oct;152(4 Pt 1):1309-15. Unique Identifier : AIDSLINE MED/96023209; Mundy LM; Auwaerter PG; Oldach D; Warner ML; Burton A; Vance E; Gaydos CA; Joseph JM; Gopalan R; Moore RD; et al; Department of Medicine, Johns Hopkins Medical Institutions,; Baltimore, Maryland, USA.; This cross-sectional and prospective one year study evaluated adults admitted to an inner city hospital with community-acquired pneumonia. The study used extensive diagnostic methods to evaluate the etiologies of community-acquired pneumonia in hospitalized patients with differing immunologic status. Of 385 study pati
Pneumocystis carinii pneumonia: a major complication of immunosuppressive therapy in patients with Wegener's granulomatosis [letter; comment]: Am J Respir Crit Care Med. 1995 Oct;152(4 Pt 1):1424. Unique Identifier : AIDSLINE MED/96023225; Vincent F; Bensoussan TA
Immunity and immunopathology to respiratory syncytial virus. The mouse model.: Am J Respir Crit Care Med. 1995 Oct;152(4 Pt 2):S59-62. Unique Identifier : AIDSLINE MED/96023237; Openshaw PJ; St. Mary's Hospital Medical School, Imperial College of Science,; Technology and Medicine, London, United Kingdom.; Infection with respiratory syncytial virus (RSV) is a major unsolved challenge for vaccine development. RSV is worldwide in distribution and infects almost all children during the first 2 yr of life. The mouse model of RSV lung disease has been very successful in reproducing many aspects of the human disease. In parti
Psychological interventions in infection with the human immunodeficiency virus.: Br J Psychiatry. 1995 Jul;167(1):104-11. Unique Identifier : AIDSLINE MED/96055765; Catalan J; Academic Department of Psychiatry, Charing Cross and Westminster; Medical School, London.; BACKGROUND. Infection with the human immunodeficiency virus (HIV) is associated with substantial psychiatric morbidity. This paper summarises the main forms of psychological intervention currently used, and reviews research evidence for their efficacy. METHOD. Publications on the mental health aspects of HIV infection
Longitudinal immunological follow-up of HIV infected haemophiliacs in Hungary.: Acta Microbiol Immunol Hung. 1995;42(2):189-98. Unique Identifier : AIDSLINE MED/96044930; Ujhelyi E; Krall G; Zimonyl I; Banhegyi D; Hollan SR; Horvath A; Fuchs D; Wachter H; Berkessy E; Fust G; National Institute of Haematology, Blood Transfusion and; Immunology, Budapest, Hungary.; Twenty-five haemophiliacs who had been infected with HIV in 1982 or 1983 were followed up from 1986 to 1993. The absolute number of the CD4+ and CD8+ cells, neopterin levels and more recently the percentage of activated, DR+ T lymphocytes were determined twice a year. In most patients a permanent decline in the CD4+ c
Bovine collagen hemostatic agent used in removal of a basal cell carcinoma of the nose with a good cosmetic result [letter]: Dermatol Surg. 1995 Oct;21(10):907-9. Unique Identifier : AIDSLINE MED/96001387; Smith KJ; Skelton HG; Turiansky G; Wagner KF
Surgical pathology of human immunodeficiency virus infection: lessons from Africa [letter; comment]: Br J Surg. 1995 Sep;82(9):1278. Unique Identifier : AIDSLINE MED/96030442; Verkuyl DA
Higher olfactory threshold and decreased odor identification ability in HIV-infected persons.: Chem Senses. 1995 Jun;20(3):325-8. Unique Identifier : AIDSLINE MED/96035088; Lehrner JP; Kryspin-Exner I; Vetter N; Department of Psychology, University of Vienna, Austria.
HIV-1 virology. Simply Marvelous nuclear transport.: Curr Biol. 1995 Jun 1;5(6):570-3. Unique Identifier : AIDSLINE MED/96028283; Goldfarb DS; Department of Biology, University of Rochester, New York; 14627-0211, USA.; HIV-1 MA protein is a viral membrane protein, but it is also involved in nuclear import of the preinitiation complex; the latter requires transfer of some MA molecules to the maturing core particle during virus assembly.
Increase in percentage of CD45RO+/CD8+ cells is associated with previous severe primary HIV infection.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):107-14. Unique Identifier : AIDSLINE MED/96007271; Bruunsgaard H; Pedersen C; Scheibel E; Pedersen BK; Department of Infectious Diseases, Rigshospitalet, Copenhagen,; Denmark.; The purpose of the study was to examine how memory (CD45RO) and naive (CD45RA) phenotypes of CD4+ and CD8+ T-cell subpopulations changed with respect to progression and duration of human immunodeficiency virus (HIV) infection. Forty-three HIV-seropositive (HIV+) subjects with known time for seroconversion were include
Positive correlation between the natural killer and gp 120/41-specific antibody-dependent cellular cytotoxic effector functions in HIV-infected individuals.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):115-9. Unique Identifier : AIDSLINE MED/96007272; Ahmad A; Menezes J; Laboratory of Immunovirology, University of Montreal, Quebec,; Canada.; Using our recently developed target system model of env gene-transfected cells for gp120/41-specific antibody-dependent cellular cytotoxicity (ADCC) assays, we evaluated the ADCC effector function of the peripheral blood mononuclear cells (PBMC) in 39 human immunodeficiency virus type 1 (HIV-1)-infected individuals. T
Effect of a retroviral immunodeficiency syndrome on resistance to MCMV: a role for natural killer cells.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):120-8. Unique Identifier : AIDSLINE MED/96007273; Peacock CD; Price P; Department of Microbiology, University of Western Australia,; Nedlands.; Mice exhibiting T cell immunodeficiency and lymphadenopathy induced by LP-BM5 MuLV (MAIDS) were assessed for their ability to control murine cytomegalovirus (MCMV) infection. Elevated replication of MCMV was observed in spleens 4-6 days after MCMV infection. Production of interfero
Effects of viral virulence on intrauterine growth in SIV-infected fetal rhesus macaques (Macaca mulatta).: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):129-38. Unique Identifier : AIDSLINE MED/96007274; Tarantal AF; Marthas ML; Gargosky SE; Otysula M; McChesney MB; Miller CJ; Hendrickx AG; California Regional Primate Research Center, University of; California, Davis 95616-8542, USA.; Studies with a simian immunodeficiency virus (SIV)-infected fetal monkey model were conducted with a focus on fetal growth and viral pathogenesis. Twenty-six fetuses were inoculated in utero via ultrasound guidance with an uncloned pathogenic strain of SIV or vehicle during the second or third trimesters [gestational
Assessment of antiretroviral therapy by plasma viral load testing: standard and ICD HIV-1 p24 antigen and viral RNA (QC-PCR) assays compared.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):139-49. Unique Identifier : AIDSLINE MED/96007275; Kappes JC; Saag MS; Shaw GM; Hahn BH; Chopra P; Chen S; Emini EA; McFarland R; Yang LC; Piatak M Jr; et al; Department of Medicine, University of Alabama at Birmingham, USA.; To assess the utility of quantitative competitive-polymerase chain reaction (QC-PCR) measurements of plasma human immunodeficiency virus type 1 (HIV-1) RNA and other viral load markers for assessment of antiretroviral therapy, we used archived cryopreserved specimens from a randomized controlled clinical trial of 135
Safety, pharmacokinetics, and antiviral response of CD4-immunoglobulin G by intravenous bolus in AIDS and AIDS-related complex.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):150-6. Unique Identifier : AIDSLINE MED/96007276; Collier AC; Coombs RW; Katzenstein D; Holodniy M; Gibson J; Mordenti J; Izu AE; Duliege AM; Ammann AJ; Merigan T; et al; Department of Medicine, University of Washington, Seattle, USA.; To assess the safety, pharmacokinetics, and antiviral effects of intravenous recombinant CD4 immunoglobulin G (CD4-IgG), a 12-week Phase One study with an optional maintenance phase was performed. Twenty-two subjects with advanced human immunodeficiency virus (HIV) infection were enrolled; 15 subjects completed the in
Efficacy, safety, and tolerance of low-dose, long-term interferon-alpha 2b and zidovudine in early-stage AIDS-associated Kaposi's sarcoma.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):157-62. Unique Identifier : AIDSLINE MED/96007277; Mauss S; Jablonowski H; Department of Medicine, Heinrich-Heine-University, Duesseldorf,; Germany.; Seventeen male homosexual outpatients with limited but progressive AIDS-associated Kaposi s sarcoma (KS) of skin, lymph nodes, oral cavity, and gastrointestinum were consecutively enrolled in an open, nonrandomized, prospective study. Patients received low-dose IFN-alpha 2b (3 MIU t.i.w.) in combination with 250 mg ZD
Substitution of didanosine sachets by chewable tablets: a pharmacokinetic study in patients with AIDS.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):163-8. Unique Identifier : AIDSLINE MED/96007278; Burger D; Meenhorst P; Mulder J; Henrichs J; Frissen J; Kroon F; ten Napel C; Koks K; Bult A; Beijnen J; Department of Pharmacy, Slotervaart Hospital, Amsterdam, The; Netherlands.; We have conducted a pharmacokinetic study of didanosine (ddI), formulated in sachets and in tablets, in patients with acquired immune deficiency syndrome (AIDS). Fifteen subjects received 250 or 167 mg of ddI twice daily as the sachet formulation and used this for at least 1 month. Subsequently, the patients were conv
Risk factors for dideoxynucleoside-induced toxic neuropathy in patients with the human immunodeficiency virus infection.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):169-74. Unique Identifier : AIDSLINE MED/96007279; Fichtenbaum CJ; Clifford DB; Powderly WG; AIDS Clinical Trials Unit, Washington University School of; Medicine, St. Louis, Missouri 63108, USA.; Dideoxynucleosides induce a dose-related toxic neuropathy; however, there is a paucity of information on whether other risk factors influence the development of neuropathy. We reviewed the records of 103 patients at an AIDS Clinical Trials Unit who were taking didanosine and/or zalcitabine to determine the risk factor
HIV incidence among New Haven needle exchange participants: updated estimates from syringe tracking and testing data.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):175-6. Unique Identifier : AIDSLINE MED/96007280; Kaplan EH; Heimer R; Yale School of Management, Yale University, New Haven,; Connecticut, USA.; This article provides updated estimates of the rate of new HIV infections among participants in New Haven s legal needle exchange program from syringe tracking and testing data. We previously reported that based on data collected from November 1990 through May 1992, the maximum likelihood incidence rate was zero with
Human immunodeficiency virus type-1 seroconversion trends among young adults serving in the United States Army, 1985-1993. United States Military Medical Consortium for Applied Retroviral Research.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):177-85. Unique Identifier : AIDSLINE MED/96007281; Renzullo PO; McNeil JG; Wann ZF; Burke DS; Brundage JF; Division of Preventive Medicine, Walter Reed Army Institute of; Research, Washington, DC, USA.; The direct measurement of the incidence of new infections with the human immunodeficiency virus type 1 (HIV-1) can be made among soldiers because of the routine and periodic nature of HIV-1 testing in the United States Army. Between November 1985 and October 1993, 978 HIV-1 seroconvers
Diagnostic utility of immune-complex-dissociated p24 antigen detection in perinatally acquired HIV-1 infection in Rwanda.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):186-91. Unique Identifier : AIDSLINE MED/96007282; Bulterys M; Farzadegan H; Chao A; Dushimimana A; Voltz A; Nawrocki P; Kurawige JB; Saah AJ; Department of Epidemiology, School of Hygiene and Public Health,; Johns Hopkins University, Baltimore, Maryland, USA.; We evaluated the diagnostic utility and prognostic value of immune-complex-dissociated (ICD) HIV-1 p24 antigen detection in a prospective cohort study of perinatally acquired HIV-1 infection in Butare, Rwanda . HIV-1 p24 antigen was measured after acid dissociation in plasma samples
Relation between human T-lymphotropic virus type I and neurologic diseases in Panama: 1985-1990.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):192-7. Unique Identifier : AIDSLINE MED/96007283; Gracia F; Castillo LC; Larreategui M; Roberts B; Cedeno V; Heneine W; Blattner W; Kaplan JE; Levine PH; Laboratorio Conmemorativo Gorgas, Panama City, Panama.; Human T-cell lymphotropic virus type I (HTLV-I) is endemic in the Caribbean basin and in Japan . HTLV-II, a closely related virus, is endemic in several groups of native Americans, including Panamanian Guaymi. In Panama, a nationwide HTLV-I/II seroprevalence of 1-2% has been reported
Quantification of HTLV-II proviral copies by competitive polymerase chain reaction in peripheral blood mononuclear cells of Italian injecting drug users, central Africans, and Amerindians.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):198-204. Unique Identifier : AIDSLINE MED/96007284; Cimarelli A; Duclos CA; Gessain A; Cattaneo E; Casoli C; Biglione M; Mauclere P; Bertazzoni U; Istituto di Genetica Biochimica ed Evoluzionistica del CNR,; Pavia, Italy.; To better correlate the burden of human T cell leukemia virus type I (HTLV-I) and type II (HTLV-II) infection with diagnostic and prognostic markers, we developed a new competitive polymerase chain reaction (PCR) assay for the quantitative determination of proviral copy numbers in infected cells. A competitive plasmid
HTLV-II detection in an Amerindian family in Colombian southern Andean region [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):205-6. Unique Identifier : AIDSLINE MED/96007285; Blank A; Yamaguchi K; Blank M; Lourido MA; Takatsuki K
Interest in HIV vaccines among Italian injection drug users. The Network Interregionale SERT [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):206-7. Unique Identifier : AIDSLINE MED/96007286; Serpelloni G; Vlahov D; Mazzi M; Rezza G
Simulation of the San Francisco HIV epidemic: AZT a possible epidemiological modulator [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):207-8. Unique Identifier : AIDSLINE MED/96007287; Lee L; Saltzberg AM; MacRae D Jr
7th International Conference on Human Retrovirology HTLV and Related Viruses. Paris, France, October 17-21, 1995. Abstracts.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):209-93. Unique Identifier : AIDSLINE MED/96007288
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