A community trial of the impact of improved sexually transmitted disease treatment on the HIV epidemic in rural Tanzania: 1. Design.

Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

A community trial of the impact of improved sexually transmitted disease treatment on the HIV epidemic in rural Tanzania: 1. Design.

AIDS. 1995 Aug;9(8):919-26. Unique Identifier : AIDSLINE MED/96014967
Hayes R; Mosha F; Nicoll A; Grosskurth H; Newell J; Todd J; Killewo J; Rugemalila J; Mabey D; London School of Hygiene and Tropical Medicine, UK.

Abstract: OBJECTIVE: To describe the rationale and design of a randomized trial of the impact of improved services for the treatment of sexually transmitted diseases (STD) on the incidence of HIV infection in Mwanza Region, Tanzania. METHODS: The likely impact of improved STD treatment services on HIV incidence, and the need for empirical information on the effectiveness of this intervention strategy, are discussed. The rationale and design of such an intervention programme in Mwanza Region, and of a community-randomized trial to measure the impact of the programme on HIV and other STD, are presented. Problems in the design and interpretation of the trial are reviewed. RESULTS: Results of the baseline survey of the cohort of over 12,000 adults in 12 communities are presented in a companion paper. CONCLUSION: There is an urgent need for effective preventive measures against the HIV epidemic in sub-Saharan Africa and other developing regions. Improved STD treatment has been promoted as a potentially effective strategy, but there is little empirical information on its impact. The trial in Mwanza Region is the first randomized study of this intervention and should provide valuable data for health policy makers.

Keywords: Adult Algorithms Community Health Services Female Human HIV Infections/*EPIDEMIOLOGY/*PREVENTION & CONTROL Male Outcome Assessment (Health Care) Prospective Studies Randomized Controlled Trials/METHODS Rural Population Sexually Transmitted Diseases/*THERAPY Support, Non-U.S. Gov't Tanzania/EPIDEMIOLOGY CLINICAL TRIAL JOURNAL ARTICLE RANDOMIZED CONTROLLED TRIAL
960228
M9621062

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