Plasmacytoid CD8 lymphoma: morphologic and immunologic characterization. NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Plasmacytoid CD8 lymphoma: morphologic and immunologic characterization.

Acta Haematol. 1995;94(4):204-9. Unique Identifier : AIDSLINE MED/96190623
Amiot L; Tas P; Caulet-Maugendre S; Goasguen J; Le Prise PY; Fauchet R; Drenou B; Laboratoire d'Hematologie-Immunologie, CHRU, Rennes, France.

Abstract: This study describes a 79 year-old female suffering from fever and lymphadenopathy. A lymph node biopsy showed diffuse infiltration of medium-sized cells with plasmacytoid features. The immunologic phenotype determined by cytometric analysis and immunochemistry showed suppressor T antigen (CD2, CD3, CD7, CD8) expression. Absence of CD5 expression characterized this abnormal T cell proliferation. Gamma T cell receptor rearrangement without immunoglobulin heavy-chain gene rearrangement confirmed the T lineage of these plasmacytoid cells and their clonality. Immunological studies are necessary for identification of this T lymphoma with B microscopic findings.
Keywords: Aged Base Sequence Case Report *CD8-Positive T-Lymphocytes DNA, Neoplasm/CHEMISTRY Female Flow Cytometry Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor Human Immunophenotyping Lymph Nodes/PATHOLOGY Lymphoma, T-Cell/GENETICS/*IMMUNOLOGY/*PATHOLOGY Molecular Sequence Data Polymerase Chain Reaction JOURNAL ARTICLEKWDagedbasesequencecasereportKWDcd8-positivet-lymphocytesdna,neoplasm/chemistryfemaleflowcytometrygenerearrangement,gamma-chaint-cellantigenreceptorhumanimmunophenotypinglymphnodes/pathologylymphoma,t-cell/genetics/KWDimmunology/KWDpathologymolecularsequencedatapolymerasechainreactionjournalarticle
960830
M9681127

Copyright © 1996 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1996. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1996. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .