Aspergillus sinusitis in patients with AIDS: report of three cases and review. NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

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Aspergillus sinusitis in patients with AIDS: report of three cases and review.

Clin Infect Dis. 1995 Sep;21(3):529-35. Unique Identifier : AIDSLINE MED/96077368
Teh W; Matti BS; Marisiddaiah H; Minamoto GY; Division of Allergy, Clinical Immunology, and Infectious; Diseases, St. Luke's/Roosevelt Hospital Center, New York, New; York 10025, USA.

Abstract: Invasive aspergillosis is an uncommon but increasingly reported complication of AIDS. Sinusitis, usually bacterial in etiology, is frequently seen among human immunodeficiency virus (HIV)-infected patients. We discuss the cases of three patients with AIDS and invasive aspergillus sinusitis seen at our institutions and those of 15 patients who are described in the literature. Seven of the 18 had brain involvement, 3 had orbital involvement, and 7 had mastoid or other bony disease. Three had evidence of concomitant invasive pulmonary aspergillosis. Of 15 patients with evaluable histories, 11 had recognized risks for invasive aspergillosis; 6 had previous sinusitis, otitis, or polyposis; and 11 had prior conditions indicative of advanced HIV-related disease. Despite aggressive surgical intervention and systemic antifungal therapy, nearly all patients died as a result of aspergillosis.
Keywords: Adolescence Adult Antifungal Agents/THERAPEUTIC USE Aspergillosis/*COMPLICATIONS/DRUG THERAPY/SURGERY AIDS-Related Opportunistic Infections/*COMPLICATIONS/DRUG THERAPY/ SURGERY Case Report Combined Modality Therapy Female Human Lung Diseases, Fungal/COMPLICATIONS Male Middle Age Prognosis Sinusitis/*COMPLICATIONS/DRUG THERAPY/SURGERY JOURNAL ARTICLE REVIEW REVIEW OF REPORTED CASESKWDadolescenceadultantifungalagents/therapeuticuseaspergillosis/KWDcomplications/drugtherapy/surgeryaids-relatedopportunisticinfections/KWDcomplications/drugtherapy/surgerycasereportcombinedmodalitytherapyfemalehumanlungdiseases,fungal/complicationsmalemiddleageprognosissinusitis/KWDcomplications/drugtherapy/surgeryjournalarticlereviewreviewofreportedcases
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M9640837

Copyright © 1996 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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