Clinical presentation of minimally invasive and in situ squamous cell carcinoma of the anus in homosexual men. NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

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Clinical presentation of minimally invasive and in situ squamous cell carcinoma of the anus in homosexual men.

Clin Infect Dis. 1995 Sep;21(3):603-7. Unique Identifier : AIDSLINE MED/96077381
Forti RL; Medwell SJ; Aboulafia DM; Surawicz CM; Spach DH; Department of Medicine, University of Washington Medical Center,; Seattle, USA.

Abstract: From January 1988 to December 1993, we identified six men with minimally invasive (stage I) squamous cell carcinoma of the anus and 10 men with anal carcinoma in situ (CIS). Of the six patients with invasive carcinoma, four were infected with human immunodeficiency virus (HIV), including one with AIDS. Of the 10 patients with CIS, eight were infected with HIV, including four with AIDS. Anal pain and bleeding were the most common symptoms of minimally invasive anal cancer and anal CIS. Anal irritation, burning, or pruritus occurred more frequently in patients with CIS, whereas anal ulcers, masses, or abscesses were more frequent in patients with minimally invasive cancer. Several patients with CIS had a discrete area of leukoplakia in the anal canal or a pigmented plaque of the anus and anal canal. These lesions were not observed in patients with minimally invasive anal cancer. The symptoms and signs of early-stage anal cancer in men at risk for developing HIV infection or men infected with HIV often resemble those of other common anorectal diseases in homosexual men. Anal cancer in HIV-infected men is not limited to those individuals with AIDS.
Keywords: Adult Anus Neoplasms/COMPLICATIONS/DIAGNOSIS/*ETIOLOGY Carcinoma in Situ/COMPLICATIONS/DIAGNOSIS/*ETIOLOGY Carcinoma, Squamous Cell/COMPLICATIONS/DIAGNOSIS/*ETIOLOGY Homosexuality, Male Human HIV Infections/COMPLICATIONS Male Risk Factors Support, U.S. Gov't, P.H.S. JOURNAL ARTICLEKWDadultanusneoplasms/complications/diagnosis/KWDetiologycarcinomainsitu/complications/diagnosis/KWDetiologycarcinoma,squamouscell/complications/diagnosis/KWDetiologyhomosexuality,malehumanhivinfections/complicationsmaleriskfactorssupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
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Copyright © 1996 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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