Mycobacterial infection in Mexican AIDS patients. NLM AIDSLINE Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.

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Mycobacterial infection in Mexican AIDS patients.

J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jan 1;11(1):53-8. Unique Identifier : AIDSLINE MED/96130047
Molina-Gamboa JD; Ponce-de-Leon S; Sifuentes-Osornio J; Bobadilla del Valle M; Ruiz-Palacios GM; Department of Infectious Diseases, National Institute of; Nutrition, Mexico City, Mexico.

Abstract: To describe the characteristics of mycobacterial infection in Mexico, we reviewed records from patients who were seen at the AIDS Clinic of the National Institute of Nutrition in Mexico City from 1983 to 1992. Of 460 AIDS patients, 118 (25.6%) were found to have mycobacterial infections by positive Ziehl-Neelsen stain, culture, or both. Cultures were completed for 66 of the 118 stain-positive specimens. Mycobacterium tuberculosis was the most common species found (n = 13), followed by M. avium complex (n = 12); 21 infections were identified a nonspecific mycobacteria other than tuberculosis (MOTT) and 20 infections were from species other than tuberculosis. Susceptibility testing was performed in only two tuberculosis cases, with one strain showing multidrug resistance. We conclude that mycobacterial infection is common among our AIDS population, and MOTT may be at least as common as M. tuberculosis. Previous reports of the rarity of MOTT could be related to the lack of adequate diagnostic methods in developing countries.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adolescence Adult Aged Antitubercular Agents/THERAPEUTIC USE AIDS-Related Opportunistic Infections/DRUG THERAPY/*EPIDEMIOLOGY/ ETIOLOGY Drug Therapy, Combination Female Human Male Mexico/EPIDEMIOLOGY Microbial Sensitivity Tests Middle Age Mycobacterium avium Complex/ISOLATION & PURIF Mycobacterium avium-intracellulare Infection/DRUG THERAPY/ EPIDEMIOLOGY/ETIOLOGY Mycobacterium tuberculosis/ISOLATION & PURIF Mycobacterium Infections/DRUG THERAPY/*EPIDEMIOLOGY/ETIOLOGY Survival Rate Tuberculosis/DRUG THERAPY/EPIDEMIOLOGY/ETIOLOGY JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadolescenceadultagedantitubercularagents/therapeuticuseaids-relatedopportunisticinfections/drugtherapy/
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Copyright © 1996 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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