Changing clinical manifestation of pediatric African Burkitt's lymphoma? (Meeting abstract). NLM AIDSLINE Important note: Information in this article was accurate in 1995. The state of the art may have changed since the publication date.

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Changing clinical manifestation of pediatric African Burkitt's lymphoma? (Meeting abstract).

Proc Annu Meet Am Assoc Cancer Res; 36:A1375 1995. Unique Identifier : AIDSLINE ICDB/95609152
Bamgbola FO; Yakubu AM; Ogala WN; Ifere OA; Bangbola NR; A.B.U. Teaching Hospital, Zaria, Nigeria

Abstract: In a recent retrospective study within a period of 18 months, we saw relatively more cases of atypical clinical manifestations (ACM) of African Burkitt's lymphoma (ABL) than were seen in 14 years of medical practice in our unit or ever reported from Nigeria. Out of 15 patients with Burkitt's lymphoma (BL), 9 (60%) had moderate to severe hepatosplenomegaly (HS), 4 (26%) had subcutaneous tissues (ST) involvement and 2 (15%) had primary bone marrow changes. These sites are mostly spared in ABL. In previous reports HS was (6.7 - 9%), ST (2.8%), PL (0.75-1.5%) and DB (1.5 - 2.4%). All patients with ACM of ABL were males with age range 5 - 8 years. HIV status assessed in only one patient was negative. However, there is increasing HIV seropositivity in our community. A more detailed evaluation of subsequent cases may explain this new trend. This may include expensive and laborious procedures, including HLA study, facility for which is not available in our Unit.
Keywords: Bone Marrow/PATHOLOGY Burkitt's Lymphoma/*DIAGNOSIS/PATHOLOGY Child Child, Preschool Diagnosis, Differential Female Human HIV Seropositivity/DIAGNOSIS/PATHOLOGY Male Nigeria ABSTRACTKWDbonemarrow/pathologyburkitt'slymphoma/KWDdiagnosis/pathologychildchild,preschooldiagnosis,differentialfemalehumanhivseropositivity/diagnosis/pathologymalenigeriaabstract
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