AIDS Alert. 1995 Apr;10(4):52-4. Unique Identifier : AIDSLINE AIDS/95700225
Abstract:
As many as 12 percent of HIV-infected homosexual men in the United States could remain AIDS-free for 20 years after seroconversion, and the median length of survival for children with AIDS may now be as high as eight years, according to several new studies presented at a national conference. At the Second National Conference on Human Retroviruses and Related Infections in Washington, D.C., researchers estimated that the percentage of long-term survivors in the United States is about 5-10 percent. Director of the National Institute of Allergy and Infectious Diseases, Anthony Fauci, MD, reported that immune system cells, also called CD8 cells, may be more efficient than antiretroviral therapy in repressing HIV infection, as reported in the January 26, 1995 issue of the New England Journal of Medicine. Interleukin-2, a natural protein that induces CD8 cells to suppress the virus, is showing promising preliminary results. Another study, published in the December 1994 issue of AIDS Research and Human Retroviruses, suggests that a women infected with the virus thirteen years ago through a blood transfusion but who has little trace of the virus in her blood, is able to suppress all HIV viruses that infected her and only defective, slow-growing viruses have remained within her white cells. Another study suggests that ongoing high-risk behavior might be associated with rapid progression and that people might be superinfected with more pathogenic virus.
Keywords: Acquired Immunodeficiency Syndrome/IMMUNOLOGY/*MORTALITY Child Disease Progression Female Homosexuality, Male Human HIV/ISOLATION & PURIF HIV Infections/BLOOD/TRANSMISSION HIV Seropositivity/IMMUNOLOGY/*MORTALITY Male Survival Analysis Survivors/STATISTICS & NUMER DATA Time Factors NEWSLETTER ARTICLE 951030
M95A0959
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