Enteric viruses associated with HIV infection in Tanzanian children with chronic diarrhea. NLM AIDSLINE Important note: Information in this article was accurate in 1995. The state of the art may have changed since the publication date.

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Enteric viruses associated with HIV infection in Tanzanian children with chronic diarrhea.

Pediatr AIDS HIV Infect. 1994 Oct;5(5):296-9. Unique Identifier : AIDSLINE AIDS/95330393
Cegielski JP; Msengi AE; Miller SE; Department of Medicine, Duke University Medical Center, Durham,; North Carolina, USA.

Abstract: OBJECTIVE. To determine whether specific viruses are associated with HIV infection in Tanzanian children with chronic diarrhea. DESIGN. Cross-sectional survey. SETTING. Major national teaching hospital in Dar es Salaam, Tanzania. PATIENTS. Consecutively admitted, human immunodeficiency virus (HIV)-infected and HIV-uninfected children with chronic diarrhea, and controls without diarrhea, aged 15 months to 5 years. MAIN OUTCOME MEASURE. Enteric viruses identified by electron microscopy (EM) of fecal specimens. RESULTS. Small round structured viruses (SRSV) were more frequent in HIV-infected than HIV-uninfected children with chronic diarrhea (4 of 21 vs 1 of 32, prevalence ratio = 6.09, 90% confidence limits 1.03, 36.14). Rotavirus and coronavirus-like particles (CVLP) were not associated with HIV infection. CONCLUSION. SRSV may be associated with HIV infection in Tanzanian children with chronic diarrhea. Larger, confirmatory studies are needed.
Keywords: AIDS-Related Opportunistic Infections/COMPLICATIONS/*VIROLOGY Chronic Disease Coronavirus/ISOLATION & PURIF Cross-Sectional Studies Diarrhea/*COMPLICATIONS/VIROLOGY Feces/MICROBIOLOGY Gastroenteritis/COMPLICATIONS/VIROLOGY Human Norwalk Virus/ISOLATION & PURIF Rotavirus/ISOLATION & PURIF Support, Non-U.S. Gov't Tanzania Virus Diseases/*COMPLICATIONS JOURNAL ARTICLEKWDaids-relatedopportunisticinfections/complications/KWDvirologychronicdiseasecoronavirus/isolation&purifcross-sectionalstudiesdiarrhea/KWDcomplications/virologyfeces/microbiologygastroenteritis/complications/virologyhumannorwalkvirus/isolation&purifrotavirus/isolation&purifsupport,non-uKWDsKWDgov'ttanzaniavirusdiseases/KWDcomplicationsjournalarticle
951030
M95A0917

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