Measles immunity in HIV-infected children. NLM AIDSLINE Important note: Information in this article was accurate in 1995. The state of the art may have changed since the publication date.

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Measles immunity in HIV-infected children.

Pediatr AIDS HIV Infect. 1994 Oct;5(5):300-4. Unique Identifier : AIDSLINE AIDS/95330394
Walter EB; Katz SL; Bellini WJ; Department of Pediatrics, Duke University Medical Center, Durham,; North Carolina, USA.


Abstract: In a retrospective study, sera from 84 children of human immunodeficiency virus (HIV)-seropositive mothers (35 HIV-infected and 49 uninfected children) with a known date of receipt of measles, mumps, and rubella vaccine were tested for antibody to measles vaccine by an indirect enzyme immunoassay (EIA) method and/or microneutralization (NEUT). At the time of last measurement, 21/35 (60.0%) HIV-infected children remained seropositive by either EIA or NEUT. Forty seven of forty-nine (95.9%) uninfected children had evidence of measles antibody. Six HIV-infected children had a documented loss of antibody over time. The majority of HIV-infected children had antibody to measles vaccine virus, which in some cases decreased over time.
Keywords: Antibodies, Viral/*ANALYSIS Human HIV Infections/*IMMUNOLOGY Immunization Immunoenzyme Techniques Infant Measles Vaccine/*IMMUNOLOGY Measles Virus/IMMUNOLOGY Mumps Vaccine/IMMUNOLOGY Neutralization Tests Retrospective Studies Rubella Vaccine/IMMUNOLOGY Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. Vaccines, Combined/IMMUNOLOGY JOURNAL ARTICLEKWDantibodies,viral/KWDanalysishumanhivinfections/KWDimmunologyimmunizationimmunoenzymetechniquesinfantmeaslesvaccine/KWDimmunologymeaslesvirus/immunologymumpsvaccine/immunologyneutralizationtestsretrospectivestudiesrubellavaccine/immunologysupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDvaccines,combined/immunologyjournalarticle
951030
M95A0916

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