Virucidal effects of the steam distillate from Houttuynia cordata and its components on HSV-1, influenza virus, and HIV. NLM AIDSLINE Important note: Information in this article was accurate in 1995. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Virucidal effects of the steam distillate from Houttuynia cordata and its components on HSV-1, influenza virus, and HIV.

Planta Med. 1995 Jun;61(3):237-41. Unique Identifier : AIDSLINE MED/95343014
Hayashi K; Kamiya M; Hayashi T; Department of Virology, Toyama Medical and Pharmaceutical; University, Japan.

Abstract: The steam distillate prepared from fresh plants of Houttuynia cordata Thunb. (Saururaceae) was found to have direct inhibitory activity against herpes simplex virus type 1 (HSV-1), influenza virus, and human immunodeficiency virus type 1 (HIV-1) without showing cytotoxicity, but not against poliovirus and coxsackie-virus. The loss of viral infectivity was related to the duration of drug treatment. Three major components of the distillate, methyl n-nonyl ketone, lauryl aldehyde, and capryl aldehyde, also inactivated HSV-1, influenza virus, and HIV-1. These in vitro findings demonstrate that the essential oils provide virucidal activity against enveloped viruses by interfering with the function of virus envelope.
Keywords: Animal Antiviral Agents/ISOLATION & PURIF/*PHARMACOLOGY Cell Line Cell Survival/DRUG EFFECTS Dogs Hela Cells Herpesvirus 1, Human/*DRUG EFFECTS/PHYSIOLOGY Human HIV-1/*DRUG EFFECTS/PHYSIOLOGY Japan Kidney Medicine, Oriental Traditional Orthomyxovirus Type A, Human/*DRUG EFFECTS/PHYSIOLOGY Plant Extracts/*PHARMACOLOGY *Plants, Medicinal Virus Replication/DRUG EFFECTS JOURNAL ARTICLEKWDanimalantiviralagents/isolation&purif/KWDpharmacologycelllinecellsurvival/drugeffectsdogshelacellsherpesvirus1,human/KWDdrugeffects/physiologyhumanhiv-1/KWDdrugeffects/physiologyjapankidneymedicine,orientaltraditionalorthomyxovirustypea,human/KWDdrugeffects/physiologyplantextracts/KWDpharmacologyKWDplants,medicinalvirusreplication/drugeffectsjournalarticle
951030
M95A0170

Copyright © 1995 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1995. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1995. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .