1995

[Sindrom na pridobita imunna nedostatuchnost (SPIN) / vremenni metodichni ukazaniia.]: Tolbukhin Khigienno-epidemiologichna inspektsiia gr. Tolbukhin 1987 27 p Unique Identifier : AIDSLINE CAT/9401690
[AIDS : insidia biologica e disagio psicosociale.]: Torino : UTET libreria, c1990 viii, 308 p. : ill Unique Identifier : AIDSLINE CAT/9402478; Cazzullo CL
[AIDS--organizzazione, prevenzione, assistenza e ricerca nel Piano sanitario bolognese.]: [Bologna] : Comune di Bologna : Calderini, c1990 xxv, 173 p. : ill Unique Identifier : AIDSLINE CAT/9402622
Current issues in the management of patients with HIV infection.: London : Mediscript, c1991 iv, 126 p. : ill (Therapeutic strategies in oncology ; 5) Unique Identifier : AIDSLINE CAT/9514125; Krown SE
Meeting AIDS with compassion : AIDS care and prevention in Agomanya, Ghana. 1st ed.: London : ActionAid, c1991 (1994 printing) 31 p. : ill (Strategies for hope ; no. 4) Unique Identifier : AIDSLINE CAT/9514284; Hampton J
[Eizu kenkyu no saisentan.]: Tokyo : Yodosha, 1993 166 p. : ill (Rinshoi no tame no jikken igaku shirizu ; 12) Unique Identifier : AIDSLINE CAT/9417604; Hattori T
Partners against AIDS : lessons learned : AIDSCOM.: Washington, DC : Academy for Educational Development, [1993] xvii, 128 p Unique Identifier : AIDSLINE CAT/9434140
A:world against AIDS : communication for behavior change.: Washington, DC : Academy for Educational Development, [1993] x, 285 p. : ill Unique Identifier : AIDSLINE CAT/9434141; Smith WA
Inspection of local authority services for people affected by HIV/AIDS : overview.: Nottingham : Social Services Inspectorate, Central Inspection Group, Dept. of Health, 1994 86 p Unique Identifier : AIDSLINE CAT/9514150
[AIDS e sindromi correlate : VII convegno nazionale : Bari, 12-14 novembre 1993.]: Bologna : Monduzzi editore, c1994 734 p. : ill Unique Identifier : AIDSLINE CAT/9508235; Pastore G
[Eine:Bedarfsanalyse zur Kommunikation zwischen Arzt und HIV-Patient in Deutschland.]: Koln : Gabriele Klein Verlag, 1994 158 p. : ill Unique Identifier : AIDSLINE CAT/9505251; Seidel K
[Catalogo de organizacoes nao-governamentais : with partial English version.]: (Brazil) [Brazil] : A Programa, c1994 130 p Unique Identifier : AIDSLINE CAT/9507505
The:AIDS leader : an international digest of organizational responses to AIDS & HIV. Vol. 1, no. 1 (Jan. 1995)-: Bradford, UK : Modus Operandi Partnership, c1995- v Unique Identifier : AIDSLINE CAT/9508157
[Le:traumatisme de la mort annoncee : psychosomatique et sida.]: Paris : Dunod, c1995 viii, 196 p (Psychismes) Unique Identifier : AIDSLINE CAT/9508273; Thome-Renault A
Adult T cell leukemia and related diseases.: New York : Springer-Verlag ; Austin : R.G. Landes, c1995 139 p. : ill (Medical intelligence unit) Unique Identifier : AIDSLINE CAT/9510718; Uchiyama T; Yodoi J
Aids and the public debate : historical and contemporary perspectives.: Amsterdam ; Washington, DC : IOS Press ; Tokyo : Ohmsha, 1995 vii, 216 p. : ill Unique Identifier : AIDSLINE CAT/9512776; Hannaway C; Harden VA; Parascandola J
Culture and sexual risk : anthropological perspectives on AIDS.: Amsterdam : Gordon and Breach Publishers, c1995 xxvii, 355 p Unique Identifier : AIDSLINE CAT/9514415; Brummelhuis Ht; Herdt GH
HIV testing and screening : entering the second decade : a forum for journalists.: [Menlo Park, CA? : Henry J. Kaiser Family Foundation? 1995?] 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9514873
Epidermoid anal cancer in HIV-infected patients (Meeting abstract).: Br J Cancer; 70(Suppl 22):17 1994. Unique Identifier : AIDSLINE ICDB/95611642; Bottomley D; Gershuny A; Govindaraju S; Phillips RH; Department of Radiotherapy, Charing Cross Hospital, London W6, UK; Anal cancer is un uncommon malignancy but it appears to occur at an increased frequency in homosexual men who partake in receptive anal intercourse. The human immunodeficiency virus (HIV) has not been shown to be an independent risk factor in anal carcinoma since in population cohorts of intravenous drug abusers and h
The prospects for immunotherapy of virus associated cancers (Meeting abstract).: Br J Cancer; 69(Suppl 21):4 1994. Unique Identifier : AIDSLINE ICDB/95611940; Melief CJ; Dept. of Immunohematology and Blood Bank, Univ. Hosp. Leiden,; P.O. Box 9600, 2300 RC Leiden, The Netherlands; Immunotherapy of tumors by adoptive transfer of cytotoxic T cells (CTL) is now feasible in experimental murine systems. These CTL recognize peptide sequences of defined length presented in the groove of MHC class I molecules. Effective eradication of large tumor masses requires co-administration of
Retroviral vector-mediated gene transfer into peripheral blood lymphocytes: a target cell type for gene therapy of congenital and acquired disorders (Meeting abstract).: Gene Ther; 1(Suppl 2):S2 1994. Unique Identifier : AIDSLINE ICDB/95612713; Bordignon C; Ist. Scientifico H.S. Raffaele, Milan, Italy; Peripheral blood lymphocytes (PBLs) are key target cells for gene therapy of a number of inherited and acquired blood disorders We have systematically analyzed the crucial variables involved in high efficiency gene transfer with specific attention to in vitro and in vivo functional properties associated with cell mani
The non-gamma(c)R T-cell growth factors--cytokine gene for cancer and transplantation (Meeting abstract).: Gene Ther; 1(Suppl 2):S4 1994. Unique Identifier : AIDSLINE ICDB/95612716; Lotze MT; Tahara H; Storkus WJ; Zitvogel L; Suzuki T; Berman R; Robbins PB; Pittsburgh Cancer Inst., Pittsburgh, PA 15261; The development of effective gene therapies using cytokines requires an understanding of the differential effects of individual cytokines as paracrine agents during the course of an immune response. We have created retroviral vectors based on the modified Maloney retroviral vector, MFG expressing a single, double (DFG
Hepatitis B and C viruses, human T-cell lymphotrophic virus (HTLV I, II), and leukemias. A case control study (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 36:A1666 1995. Unique Identifier : AIDSLINE ICDB/95609441; Gentile G; Mele A; Monarca B; Vitale A; Pulsoni A; Visani G; Castelli G; Rapicetta M; Verani P; Martino P; et al; Istituto Superiore di Sanita, Rome, Italy; We investigated the relationships between acute myeloid leukemia, acute lymphocytic leukemia, chronic myeloid leukemia and refractory anemia with excess of blasts and antibodies to human T lymphotropic (HTLV) virus type I and II and hepatitis B and C viruses in a multicenter case control study on risk factors for acut
Distribution of HLA in a population of Black patients with HTLV-I associated adult T-cell leukemia/lymphoma (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 36:A1667 1995. Unique Identifier : AIDSLINE ICDB/95609442; White JD; Manns A; Johnson JA; Waldmann TA; NCI, Bethesda, MD 20892; Human leukocyte antigens (HLA) play an important role in regulating the immune response to infectious agents and determinants of malignant transformation. We compared the HLA frequency of 25 Black patients with adult T-cell leukemia/lymphoma (ATL) referred for therapy, to a racially similar, healthy control (CO) popul
Effect of HTLV-I infection on incidence of non-Hodgkin's lymphoma in Jamaica and Trinidad (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 36:A1668 1995. Unique Identifier : AIDSLINE ICDB/95609443; Cleghorn F; Manns A; Falk R; Hartge P; Jaffe E; Hanchard B; Bartholomew C; Blattner W; DCE/NCI/NIH, Bethesda, MD; Incidence rates for non-Hodgkin s lymphoma (NHL) were calculated using all incident cases diagnosed in Jamaica during 1984-1987, and all incident cases of African descent in
Polyanionic chemical barriers to HIV-1 binding in CD4 expressing cells (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 36:A1790 1995. Unique Identifier : AIDSLINE ICDB/95609565; Zalkow LH; Burgess EM; Ruell JA; Gruszecka-Kowalik E; Lu H; School of Chemistry and Biochemistry, Georgia Institute of; Technology, Atlanta, GA 30332; Using sulfonated azo-dyes as lead compounds, over 125 compounds have been synthesized and screened for their in vitro anti-HIV activity. A QSAR was developed based on electron density distributions and EC50 values. Azo linkages and sulfonic acid residues have been replaced, systematically, by amide linkages and carbox
WSU-Br1: A novel human breast xenograft model (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 36:A1851 1995. Unique Identifier : AIDSLINE ICDB/95609626; LoRusso PM; Polin L; Visscher D; Jones J; Jones LA; Demchik L; Kushner J; Corbett TH; Wayne State Univ., Detroit, MI 48201; Despite treatment advances in medical oncology, metastatic breast cancer remains a serious, incurable disease taking the lives of more than 44,000 American women/year. Both new treatment modalities and new tools of drug discovery must be developed. In September, 1992, an HIV-, chemotherapy naive, 45 y/o female underwe
Evidence of a clonal T-cell immune response in patients with breast cancer (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 14:A108 1995. Unique Identifier : AIDSLINE ICDB/95613263; Ito K; Chang MY; Vinciguerra V; Silver J; Fetten JV; Don Monti Division of Medical Oncology, North Shore Univ. Hosp.,; Manhasset, NY 11030; Evidence is accumulating that an immune response directed against tumor cells develops in patients with breast cancer. The degree to which this participates in the control of disease is unknown, but several intriguing findings are known: (1) Two unique antigens are present on breast cancer cells which are absent in th
Primary follicular lymphoma of the meninges: a case report (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 14:A308 1995. Unique Identifier : AIDSLINE ICDB/95613462; Subramanian S; Bahceci E; Kanji A; Mercy Hosp. and Medical Center, Chicago, IL 60616; The incidence of primary lymphomas of brain is increasing. The incidence of primary meningeal lymphoma is approx 1% of these. Review of literature indicates no report of follicular primary meningeal lymphomas. We report a follicular large cell lymphoma of the meninges presenting as a mass in a nonimmunocompromised you
Reed-Sternberg (RS) cells are natural hybridomas? (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 14:A328 1995. Unique Identifier : AIDSLINE ICDB/95613482; Sinkovics J; Cancer Inst., St. Joseph's Hosp., Tampa, FL 33607; Over 20 yr ago our team working at MD Anderson Hospital encountered 2 viral agents in Hodgkin s disease (HD): (1) an as yet unidentified retrovirus functioning as envelope donor to a defective mouse leukemia virus; and (2) a herpes virus that later turned out to be EBV. Patients with HD had antibodies to both of these
Increasing incidence of primary central nervous system lymphoma (PCNSL) in the elderly: Florida Cancer Data Systems (FCDS) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 14:A421 1995. Unique Identifier : AIDSLINE ICDB/95613574; Phuphanich S; Werner M; Lyman G; Neuro-Oncology Program and Medical Oncology Services, H. Lee; Moffitt Cancer Center and Research Institute, Tampa, FL; PCNSL is a rare neoplasm but one that is being seen with increasing frequency even in immunocompetent patients and also in patients with Acquired Immune Deficiency Syndrome (AIDS). We analyzed 6357 cases of primary malignant brain tumors reported to the FCDS from 1981-1989. Incidence rates per 100,000 population were
Treatment of HIV related non-Hodgkin's lymphoma (NHL) with chemotherapy (CT) and granulocyte-colony stimulating factor (G-CSF): reduction of toxicity and of days of hospitalization with concomitant overall reduction of the cost (Meeting abstract).: Sixth International Symposium, Supportive Care in Cancer, March 2-5, 1994, New Orleans, LA. Multinational Association of Supportive Care in Cancer, Brussels, Belgium, AO-5, 1994.. Unique Identifier : AIDSLINE ICDB/95611920; Tirelli U; Vaccher E; Spina M; Errante D; Tavio M; Polizzi P; Bernardi D; Talamini R; Carbone A; Div. of Medical Oncology and AIDS, C.R.O., Italy; The aim of this study is to compare the toxicity and the cost of CT with G-CSF vs CT without G-CSF. We have analyzed 37 consecutive patients (pts) treated with intensive CT regimens, 19 pts from July 1989 to June 1991 without G-CSF and 18 pts from July 1991 to September 1992 with G-CSF, 5 ug/kg/day sc starting 24 hr a
Treatment options and care of HIV-infected pregnant women.: Pediatr AIDS HIV Infect. 1994 Dec;5(6):333-43. Unique Identifier : AIDSLINE AIDS/95368369; Stratton P; Contraceptive Development Branch, National Institutes of Child; Health and Human Development, Bethesda, Maryland, USA.
Reduced immunoglobulin kappa/lambda light chain ratio in perinatally HIV-1-infected children.: Pediatr AIDS HIV Infect. 1994 Dec;5(6):344-9. Unique Identifier : AIDSLINE AIDS/95368370; Saitta M; Gaido F; Palomba E; Cirina P; Giaccone A; Ciuti E; Tovo P; Laboratory of Clinical Chemistry and Microbiology, Regina; Margherita Children's Hospital, Turin, Italy.; In 27 perinatally human immunodeficiency virus type 1 (HIV-1)-infected children, we measured, by immunonephelometry, the kappa/lambda light chain ratio (KLR) of serum immunoglobulins. The latter is a recently available laboratory index reflecting the balance between the synthesis of K isotypes and L isotypes. KLR was
Lack of association between anti-V3 loop antibodies and perinatal transmission of HIV-1 in Kampala, Uganda.: Pediatr AIDS HIV Infect. 1994 Dec;5(6):350-6. Unique Identifier : AIDSLINE AIDS/95368371; Epstein H; Guay L; Hom D; Mmiro F; Ndugwa C; Marum L; Olness K; Piwowar E; Kataaha P; Baenziger J; et al; Department of Biochemistry, Makerere University, Kampala, Uganda.; This study evaluated the association between reactivity of maternal antibody to human immunodeficiency virus type 1 (HIV-1) V3 loop peptides and perinatal transmission in Uganda . Plasma from 40 HIV-1-infected mothers (20 transmitting and 20 nontransmitting mothers) and 31 uninfecte
Oral zinc supplementation in the treatment of HIV-infected children.: Pediatr AIDS HIV Infect. 1994 Dec;5(6):357-60. Unique Identifier : AIDSLINE AIDS/95368372; Reich EN; Church JA; Division of Allery-Clinical Immunology, Childrens Hospital, Los; Angeles, California, USA.; Primary zinc (Zn) deficiency has been reported to cause immune dysfunction; secondary Zn deficiency has been noted in HIV-infected adults; and in vitro studies have suggested that Zn may have antiviral activity. Zn supplementation was studied in HIV-infected children to evaluate selected clinical and laboratory respon
Kliks, S.C. et al., Features of HIV-1 that could influence maternal-child transmission. JAMA 1994; 272:467-74.: Pediatr AIDS HIV Infect. 1994 Dec;5(6):361-2. Unique Identifier : AIDSLINE AIDS/95368373; MacDonald MG; Department of Neonatology, Children's National Medical Center,; Washington, D.C., USA.
Schur, C.L., et al., Health insurance coverage of persons with HIV-related illness: data from the ACSUS Screener. AIDS Cost and Services Utilization Survey (ACSUS) Report No. 2. AHCPR Pub. No. 94-0009 Rockville, MD: Agency for Health Care Policy and Research, 1994.: Pediatr AIDS HIV Infect. 1994 Dec;5(6):362-6. Unique Identifier : AIDSLINE AIDS/95368374; Schur CL; Berk ML
Xth International Conference on AIDS and Vth STD World Congress. Yokohama, Japan, August 1994. Selected abstracts, part 1.: Pediatr AIDS HIV Infect. 1994 Dec;5(6):367-86. Unique Identifier : AIDSLINE AIDS/95368375
HIV/AIDS and spirituality: selected bibliography.: Pediatr AIDS HIV Infect. 1994 Dec;5(6):400. Unique Identifier : AIDSLINE AIDS/95368376
New medicines in development for AIDS: 1994 survey from the Pharmaceutical Research and Manufacturers of America.: Pediatr AIDS HIV Infect. 1995 Apr;6(2):101-10. Unique Identifier : AIDSLINE AIDS/95368377
Review: pain associated with HIV infection.: Pediatr AIDS HIV Infect. 1995 Apr;6(2):63-74. Unique Identifier : AIDSLINE AIDS/95368378; Hirschfeld S; Morris BK; Pediatric Branch, National Cancer Institute, Bethesda, MD, USA.
Coinfection with herpesviruses in young children of HIV-infected women.: Pediatr AIDS HIV Infect. 1995 Apr;6(2):75-82. Unique Identifier : AIDSLINE AIDS/95368379; Sever JL; Rakusan TA; Ellaurie M; Frenkel N; Wyatt LS; Campos JM; O'Donnell RM; Price MV; Children's National Medical Center, George Washington University; Medical Center, Washington, D.C., USA.; Coinfection with herpesviruses in young children born to human immunodeficiency virus (HIV)-infected women was studied with blood samples from children who were 9-12 months and 15-24 months of age. Three groups of children were included: (I) HIV-uninfected, asymptomatic (HIV-); (II) polymerase chain reaction (PCR) and
Effect of zidovudine on human fetal lung development.: Pediatr AIDS HIV Infect. 1995 Apr;6(2):83-90. Unique Identifier : AIDSLINE AIDS/95368380; DiMaio MF; Ting A; Hsu MT; Gil J; Kattan M; Jack and Lucy Clark Department of Pediatrics, Mount Sinai School; of Medicine, New York, New York, USA.; Zidovudine ( AZT ) is currently used to treat human immunodeficiency virus (HIV)-positive women during pregnancy to prevent the prenatal transmission of HIV type 1 (HIV-1). However, AZT not only inhibits HIV replication but also affects the DNA polymera
Factors contributing to delayed diagnosis of HIV-infected women and their children in south Texas.: Pediatr AIDS HIV Infect. 1995 Apr;6(2):91-6. Unique Identifier : AIDSLINE AIDS/95368381; Doran TI; University of Texas Health Science Center at San Antonio,; Department of Pediatrics, USA.; Preliminary results from a previous study at a family human immunodeficiency virus (HIV) clinic in South Texas indicated that HIV-positive (HIV+) children from small communities were usually infected and often symptomatic at the time of referral. The current study evaluated rates of vertical transmission and factors t
HIV-1 recombinant gp160 vaccine given in accelerated dose schedules. Clin Exp Immun 1994;98:178-84.: Pediatr AIDS HIV Infect. 1995 Apr;6(2):97-8. Unique Identifier : AIDSLINE AIDS/95368382; DePalma L; George Washington University Medical Center, Washington, D.C.,; USA.
Prospective comparison of mother-to-child transmission of HIV-1 and HIV-2 in Abidjan, Ivory Coast.: Pediatr AIDS HIV Infect. 1995 Apr;6(2):99-100. Unique Identifier : AIDSLINE AIDS/95368383; MacDonald MG; Department of Neonatology, Children's National Medical Center,; Washington, D.C.
Diagnosis and detection of drug-resistant strains of M. tuberculosis. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Clin Care. 1995 Apr;7(4):27-9, 36. Unique Identifier : AIDSLINE AIDS/95700180; Ferraro MJ; Klietmann, W; Lee JT; Massachusetts General Hospital, Clinical Laboratories, Boston,; MA.; Factors contributing to the recent upswing in tuberculosis (TB) cases in the United States include the shifting of management of TB cases from specialized hospital units to lesser-equipped outpatient settings; reduced medical school teaching of TB-related issues; large-scale immigratio
Second National Conference on Human Retroviruses. Good news, bad news, and no news. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Clin Care. 1995 Apr;7(4):30, 33. Unique Identifier : AIDSLINE AIDS/95700181; Del Rio, C; Consejo Nacional de Prevencion y Control del SIDA, Mexico City,; Mexico.; The second annual National Conference on Human Retroviruses and Related Infections was held in Washington, D.C., January 29-February 2, 1995. Lectures addressed such topics as viral dynamics, United States AIDS epidemiology, immunopathogenesis, antiretroviral therapy, and HIV vaccines.
T-cell counts and what they mean. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Clin Care. 1995 Apr;7(4):31-2. Unique Identifier : AIDSLINE AIDS/95700182; Langlois W; Sax P; Harvard Community Services Center, Cleveland, OH.; The blood contains red, oxygen-carrying cells and white, immune-system cells. The T-cell count measures white blood cells, and is determined by multiplying together the following three numbers: 1) the total number of white blood cells; 2) the percentage of white blood cells that are lymphocytes; and 3) the percentage
AIDS task force grapples with faster access to protease drugs. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: J Int Assoc Physicians AIDS Care. 1995 Mar;1(2):6-11. Unique Identifier : AIDSLINE AIDS/95700332; Mascolini M; Three key questions were addressed at the February 23-24 meeting of the National Task Force on AIDS Drugs Development: 1) what can be done to accelerate approval of the protease inhibitors , 2) can enough drug be obtained from the manufacturing process to permit expa
Protease developers skirmish over possible pitfalls. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: J Int Assoc Physicians AIDS Care. 1995 Mar;1(2):13-6. Unique Identifier : AIDSLINE AIDS/95700333; Mascolini M; Protease inhibitors were the dominating topic at the Second National Conference on Human Retroviruses and Related Infections, held January 29 through February 2, 1995. Currently, seventeen protease inhibitors are in development, most falling into three categories: C
Clinical progress and transmission perils stressed at second human retroviruses conference. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: J Int Assoc Physicians AIDS Care. 1995 Mar;1(2):19-29. Unique Identifier : AIDSLINE AIDS/95700334; Mascolini M; The Second Human Retroviruses Conference covered many topics, including statistics on the viruses prevalence in American society and some survey results on sexual behavior. Conference meetings were dominated by discussions on protease inhibitors and current clinica
Loss of naive T cells may play major role in weakened immune response. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: J Int Assoc Physicians AIDS Care. 1995 Mar;1(2):32. Unique Identifier : AIDSLINE AIDS/95700335; Prescott LM; New evidence suggests that HIV weakens the patient s immune system not by devastating the body s CD4+ cells, but by destroying naive T cells. In people with AIDS, naive T cell and (adult) memory cell ratio become skewed, with about eighty percent of the T cells being memory T cells. Naive T cell loss reduces the patie
Mozambican healers join government in fight against AIDS. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: J Int Assoc Physicians AIDS Care. 1995 Mar;1(2):32. Unique Identifier : AIDSLINE AIDS/95700336; Fleming J; Mozambique is using, in conjunction with standard medical care, traditional healers (curandeiros) for people infected with HIV. Such healers provide advice on everything from watching diets to abstaining from sex. This approach is being used because of the scarcity of physician
Africa must revoultionize healthcare, say experts. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: J Int Assoc Physicians AIDS Care. 1995 Mar;1(2):34. Unique Identifier : AIDSLINE AIDS/95700337; Borst B; The World Health Organization (WHO) and the World Bank have published a study that suggests low-income African countries can overhaul their health systems and offer health services for as little as thirteen dollars per person per year. The average per capita African expenditure is now
Merck protease inhibitor MK-639 -- trial cities announced. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Apr 7;(no 220):1-2. Unique Identifier : AIDSLINE AIDS/95700338; Merck will conduct two large trials to test MK-639, a protease inhibitor. One trial is for people who have never taken AZT or other antiretrovirals, and the other is for those who have used AZT. These trials will be conducted in numerous cities across
ICC trials -- enrollment problems. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Apr 7;(no 220):2-3. Unique Identifier : AIDSLINE AIDS/95700339; Some controversy has arisen over enrollment procedures for the Inter-Company Collaboration for AIDS Drug Development (ICC) trials. Potential participants must submit blood work that has been done within the preceding thirty days that shows probable eligibility (CD4 counts between 200 and 500 with no
3TC: expanded access will be limited. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Apr 7;(no 220):3. Unique Identifier : AIDSLINE AIDS/95700340; Glaxo, arguing limited drug supplies, has decided to limit enrollment in its 3TC program from 800 to 350 new patients per week in North America. Qualifying candidates will be placed on a waiting list on a first come, first serve, basis. It is believed
National AIDS Treatment Information Project. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Apr 7;(no 220):3. Unique Identifier : AIDSLINE AIDS/95700341; The National AIDS Treatment Information Project is producing a series of AIDS treatment fact sheets for patients and counselors. Several dozen sheets, due out in June, 1995, are being produced in five topic areas: Overview of HIV Disease, Clinical Manifestations, Opportunistic Diseases, Therapeutics, and Special Topic
Topotecan now available for HIV, PML research. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Apr 7;(no 220):4. Unique Identifier : AIDSLINE AIDS/95700342; Topotecan has shown a strong anti-HIV effect, however, SmithKline Beecham is not interested in developing it for AIDS because of its toxicity. Research is now being conducted to learn whether the toxicity and anti-HIV effect can be separated. Prospective researchers must file pre-clinical or clinical plans for SmithKl
FDA reform in Congress: AIDS community absent. Food and Drug Administration. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Apr 7;(no 220):4-5. Unique Identifier : AIDSLINE AIDS/95700343; James JS; The Food and Drug Administration ( FDA ) reform movement is quickly moving through the Republican congressional agenda with little AIDS community participation. Some expected proposals are 1) accelerated approval by the FDA, 2) FDA notification with no approval being required before Pha
3TC and protease inhibitors: citizen's petition asks faster approval. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Apr 7;(no 220):5. Unique Identifier : AIDSLINE AIDS/95700344; Log Cabin Republicans, a gay and lesbian Republican organization, has formally petitioned the Food and Drug Administration ( FDA ) to speed approval of three drugs: 3TC , saquinavir, and MK-639. The petition also explore
Proposal: monitoring program for early rapid testing of new AIDS treatments. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Apr 7;(no 220):5-8. Unique Identifier : AIDSLINE AIDS/95700345; James JS; John S. James proposes a program for the careful and consistent monitoring of experimental AIDS treatments already in use by patients and physicians. The proposal s goal is to greatly reduce the time and cost of accessing the first widely credible information about the effects of new treatments, combinations, and trea
Protease inhibitors and beyond: interview with David Feigal, M.D. [interview by John S James] Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Mar 24;(no 219):1-6. Unique Identifier : AIDSLINE AIDS/95700356; Feigal D; Dr. David Feigal, M.D., Director of the Division of Antiviral Drug Products of the U.S. Food and Drug Administration ( FDA ), agrees that protease inhibitors are the most promising single approach to HIV treatment today. There are, ho
Protease inhibitors: Merck plans larger trials, expanded access. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Mar 24;(no 219):6. Unique Identifier : AIDSLINE AIDS/95700357; James JS; Merck and Co. has announced that its comparative trial and open-label protocol for persons with HIV infection that have a CD4 count under 50--expected to start in mid 1995--could be expanded from 150 to over 1400 volunteers by the end of 1995. In addition, Merck is planning several large Phase III studies in other gro
Protease inhibitor consensus statement. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Mar 24;(no 219):7. Unique Identifier : AIDSLINE AIDS/95700358; The Protease Consensus Coalition has developed the Consensus Statement on the Accelerated Approval of Protease Inhibitors. The statement has been signed by 61 organizations, as well as over 100 individuals. According to the statement, access to protease inhibitor drugs now in development represents the best hope for d
ICC Trials -- first study enrolling. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Mar 24;(no 219):8. Unique Identifier : AIDSLINE AIDS/95700359; James JS; The Inter-Company Collaboration for AIDS Drug Development (ICC) is now enrolling for its first series of clinical trials for HIV infection for patients with CD4 (T-helper) counts between 200 and 500, who have not previously taken AZT . Each 48-week tri
Yakugai AIDS and the Yokohama Xth international AIDS conference. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):1, 22. Unique Identifier : AIDSLINE AIDS/95700360; Haas GJ; The Tenth International AIDS Conference focused on groups who often receive less attention: Asians, women, and persons with hemophilia. The conference revealed that there is a worldwide leveling of the male/female ratio of HIV infections, showing that transmission is now predominantly heterosexual and through IV drug
Defendants challenge class action certification. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):1, 33-36. Unique Identifier : AIDSLINE AIDS/95700361; Dubin CS; Wadleigh J; The National Hemophilia Foundation (NHF) and the manufacturers of Anti-Hemophilia Factor Concentrates (AHF) are being sued in a class action case for ignoring and downplaying risks of HIV infection from AHF in order to enhance their financial gain. The defendants in the case, however, have challenged the class action
Dallas, police surveillance and the NHF. National Hemophilia Foundation. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):3, 31-2. Unique Identifier : AIDSLINE AIDS/95700362; Dubin CS; In 1995, the National Hemophilia Foundation (NHF) held its annual meeting in Dallas amid ongoing controversies over AIDS and viral contamination of the U.S. blood supply. Principal topics were the class action lawsuit, delivering justice to those infected with HIV, and the legislative campaign for government compensat
National Academy of Sciences convenes public hearing on HIV and the blood supply. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):4. Unique Identifier : AIDSLINE AIDS/95700363; Dubin CS; On September 12th, the Institute of Medicine (IOM) convened a public meeting on HIV contamination of the nation s blood supply during the 1980s. A special IOM panel was created to prepare a report on how thousands of persons with hemophilia were infected with HIV through tainted blood products. Testimony was heard fro
Reiki as an alternative healing method. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):9. Unique Identifier : AIDSLINE AIDS/95700364; Kovalik D; Reiki is an Asian theory that assumes humans are energy, and that by manipulating this energy with the hands, healing can occur. The healing art of Reiki is presently practiced by 200,000 practitioners throughout the world. It is believed that this gentle form of healing, while not capable of harming anyone, can resul
The ABCs of viral hepatitis. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):10-2. Unique Identifier : AIDSLINE AIDS/95700365; Haas GJ; A short introduction to each of the known hepatitis viruses is provided, along with brief information about the transmission, associated disease progression, and treatment of each virus. All of the different hepatitis viruses in existence have the common factor of infecting the liver cells. These viruses can infect ot
Acyclovir improves survival time. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):14. Unique Identifier : AIDSLINE AIDS/95700367; Some clinical studies are indicating that acyclovir , combined with AZT , improves survival time for HIV-infected people, although exactly how acyclovir prolongs survival is not known. One study reveals a 26 perce
Protease inhibitor update. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):15. Unique Identifier : AIDSLINE AIDS/95700368; Colvin R; Haas G; New clinical trial developments surrounding anti-HIV compounds, known as protease inhibitors , are discussed for the following drugs: Merck (MK-639), Searle (SC512151), Abbott (ABT-538), Hoffman LaRoche (Saquinavir),
AZT + 3TC: early results promising. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):16. Unique Identifier : AIDSLINE AIDS/95700369; Colvin R; Haas G; The results of recent trials testing the combination of AZT and 3TC were reported at the AIDS Conferences in Glasgow, Scotland in November, and Washington, DC in February. Two sets of
Pediatrics clinical trial drops AZT-alone arm. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):17. Unique Identifier : AIDSLINE AIDS/95700370; Haas GJ; A clinical trial (ACTG 152), involving 839 symptomatic children, aged 3 months to 18 years, was modified to discontinue the AZT monotherapy arm after a review board found that children on the AZT-only arm had significantly worse symptom-free survival
FDA evaluates accelerated approval process. Food and Drug Administration. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):18. Unique Identifier : AIDSLINE AIDS/95700371; The antivirals d4T and ddC have been given accelerated approval status, providing more treatment options for persons who cannot tolerate or have developed resistance to
New drug to treat wasting syndrome. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):19. Unique Identifier : AIDSLINE AIDS/95700372; The Food and Drug Administration ( FDA ) has approved Serostim, a human growth hormone, for use in AIDS clinical trials involving AIDS patients with uncontrolled and unintended weight loss. Previous studies have shown weight gains with the use of Serostim. The drug tends to increase lea
Pregnant women and clinical trials. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):20. Unique Identifier : AIDSLINE AIDS/95700373; Kuhn D; The Food and Drug Administration s ( FDA ) 1994 policy reversal of allowing pregnant women in NIH-sponsored protocols was the main topic at its FDA-Regulated Products and Pregnant Women conference. More clinical information is needed to determine the effects of trial drugs on HIV-infect
Nevirapine triple combo results released. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):21. Unique Identifier : AIDSLINE AIDS/95700374; Preliminary results of ACTG 241 have been released. This study compared the triple therapy of nevirapine plus ddI and AZT against the double combination of ddI and AZT. Preliminary re
Oral ganciclovir approved for CMV. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):21. Unique Identifier : AIDSLINE AIDS/95700375; The Food and Drug Administration ( FDA ) approved the oral form of ganciclovir for maintenance treatment of cytomegalovirus ( CMV ) retinitis, and it is believed oral ganciclovir will be approved
Creutzfeld-Jacob disease and blood product recalls. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1994 Apr;(no 10):23. Unique Identifier : AIDSLINE AIDS/95700376; Colvin R; Dubin C; Haas G; The American Red Cross has recalled 164 lots of antihemophilic factor (AHF) and albumin, due to the potential contamination of this product with the causative agent of Creutzfeld-Jakob disease (CJD). While CJD has not been shown to be passed through blood or plasma products, it can be transmitted by human tissues and
An open letter to the hemophilia community from the Community Advocacy Working Group. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):24-6. Unique Identifier : AIDSLINE AIDS/95700377; Dubin C; Hamilton J; Kuhn D; Niederman R; Ray C; Ray L; Valdez D; Wadleigh J; The Community Advocacy Working Group (CAWG) writes an open letter to the hemophiliac community, outlining the legislative efforts on behalf of the community since 1988, the current legislative campaign of the National Hemophilia Foundation (NHF), and the creation of CAWG. CAWG was created to resolve differences betwee
The good, the bad and the ugly, part II. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):27. Unique Identifier : AIDSLINE AIDS/95700378; Dubin CS; The author provides a second installment to a previous column in which he wrote about the settlement proposal offered by Baxter and Armour and how it demonstrated industry s lack of respect for the hemophilia/HIV community. The author now argues that the courts have shown a less than exemplary track record in helping
MANN: empowered and oppressed? Men's Advocacy Network of the National Hemophilia Foundation. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):28-9. Unique Identifier : AIDSLINE AIDS/95700379; Kuhn D; The author describes the purpose and the development of MANN (Men s Advocacy Network of the NHF), a complementary response for men to the women s advocacy group WONN (Women s Outreach Network of NHF), and discusses its potency as an advocacy group. MANN s initial platform demanded changes in the NHF that required more
Una conferencia de amnesia. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):30. Unique Identifier : AIDSLINE AIDS/95700380; Haas GJ; The World Federation of Hemophilia held its 21st international meeting in Mexico City in April 1995. The crisis in current hemophilia care in developing countries is described as pathetic. One study reveals that countries not importing blood products or concentrates from the U.S. had little or no HIV transmission to p
Hypericin: an answer for safer blood? Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):36. Unique Identifier : AIDSLINE AIDS/95700381; Kuhn D; Hypericin has potent activity against HIV and other viruses, is compatible with anticoagulants used to store blood, and does not affect blood chemistry when stored for 21 days. It is now being investigated as a possible treatment for persons already infected with HIV, and it has shown that it can reduce the amount of
Legislative update. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):36. Unique Identifier : AIDSLINE AIDS/95700382; The Ricky Ray Hemophilia Relief Act of 1995 has been introduced in the House of Representatives. The legislation, drafted by three Committee of Ten Thousand (COTT) members, acknowledges the Federal government s shared responsibility for the hemophilia holocaust. If passed, each individual with a bleeding disorder infe
National conference examines HIV/AIDS in women. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: GMHC Treat Issues. 1995 Mar;9(3):1-3. Unique Identifier : AIDSLINE AIDS/95700383; Hoyt MJ; The Second Conference on HIV Infection in Women, held in Washington, D.C. on February 22 to 24, offered data addressing the manifestation of HIV infection and AIDS progression in women, including wasting syndrome, vertical transmission, pregnancy and CD4 count, genital tract infections, cervical disease, and HPV (Huma
Washington watch: the sharp right turn. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: GMHC Treat Issues. 1995 Mar;9(3):6. Unique Identifier : AIDSLINE AIDS/95700411; Hodel D; Since the Republicans have taken over Congress, there is considerable apprehension on the part of AIDS activists that important funding will dwindle in many areas. Thus far the new majority is attempting to reduce AIDS prevention funding by $23 million, and funding for the AIDS housing programs were totally eliminated
Neuro-cognitive disorders on the rise. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: GMHC Treat Issues. 1995 Mar;9(3):7-8. Unique Identifier : AIDSLINE AIDS/95700412; Link D; It has been determined that five AIDS-related brain and nervous system diseases (toxoplasmosis, cryptococcal meningitis, progressive multifocal leukoencephalopathy, central nervous system lymphoma, and sensory neuropathies) are becoming growing problems for people with AIDS. These diseases, while being the initial AID
Neurologic conditions are difficult to treat. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: GMHC Treat Issues. 1995 Mar;9(3):8-11. Unique Identifier : AIDSLINE AIDS/95700413; van Baelen G; The Multicenter AIDS Cohort Study concluded that HIV-related sensory neuropathy and four opportunistic central nervous system diseases showed a significant upward trend in incidence between 1985 and 1992. Early, aggressive treatment is often necessary for neurological conditions, since mortality and irreversible damag
Resistance: how HIV evolves to survive. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Common Factor. 1995 Apr;(no 10):13-4. Unique Identifier : AIDSLINE AIDS/95700366; Colvin R; Drug resistance, the biggest problem facing medicine today, has caused recent views of anti-HIV therapies to be pessimistic. Resistance arises in HIV due to an evolutionary process involving mutations, which are passed on to viral offspring. Continuous use of antiviral agents, such as
Second National Retrovirus conference: a further report. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: GMHC Treat Issues. 1994 Mar;9(3):4-5, 7. Unique Identifier : AIDSLINE AIDS/95700410; Torres G; It was reported at the 1995 Second National Retrovirus Conference that AIDS has now surpassed unintentional injury as the leading cause of death for male Americans between the ages of 25 to 44, and for women, AIDS is fourth behind unintentional injury. A study of multidrug resistant tuberculosis that showed improved s
Life-style, health, and politically correct science [editorial]: Mod Pathol. 1992 Nov;5(6):593-4. Unique Identifier : AIDSLINE MED/95357340; Wagner BM
The use of combined in situ hybridization and immunocytochemistry to identify HIV-infected cells in brain tissue.: Mod Pathol. 1992 Nov;5(6):649-54. Unique Identifier : AIDSLINE MED/95357354; Shapshak P; Yoshioka M; Sun NC; Schiller PC; Department of Psychiatry, University of Miami, School of; Medicine, Florida, USA.; It is frequently important to identify the types of cells that are infected with human immunodeficiency virus type-1 (HIV-1) in sections of formalin-fixed paraffin-embedded (FFPE) brain tissue. Currently, both immunocytochemical and in situ hybridization methods are used for this purpose. Combined in situ hybridizatio
Medication use in HIV+ mothers who breastfeed.: J Hum Lact. 1995 Jun;11(2):133-5. Unique Identifier : AIDSLINE MED/95344528; Christman A
Mothers' attitudes towards donated breastmilk in Jos, Nigeria.: J Hum Lact. 1995 Jun;11(2):93-6. Unique Identifier : AIDSLINE MED/95344535; Ighogboja IS; Olarewaju RS; Odumodu CU; Okuonghae HO; In many developing countries, the use of pooled human milk is not widely accepted. Six hundred eighty breastfeeding mothers were interviewed to ascertain their acceptance of donated breastmilk. Their attitudes toward stored breastmilk, human milk banking, and breastfeeding in the event of human immunodeficiency virus
J. P. Lecocq Conference on gene therapy. 5-7 July 1994 Ecole Superieure de Biotechnologie de Strasbourg, Pole API, Parc d'Innovation, Illkirch, Nr Strasbourg, France.: Biologicals. 1995 Mar;23(1):39-46. Unique Identifier : AIDSLINE MED/95344679; Meager A; Division of Immunobiology, National Institute for Biological; Standards and Control, Potters Bar, Herts, U.K.
In vitro inactivation of human immunodeficiency virus by ascorbic acid.: Biologicals. 1995 Mar;23(1):75-81. Unique Identifier : AIDSLINE MED/95344686; Rawal BD; Bartolini F; Vyas GN; Department of Laboratory Medicine, University of California, San; Francisco 94143-0134, USA.; In vitro inactivation of cell-free human immunodeficiency virus (CFHIV) was investigated by mixing replication-competent virions with aliquots of a culture medium (RPMI) containing increasing amounts (62.5-500 micrograms/ml) of ascorbic acid (AA) at pH7. Similarly, mixtures of CFHIV and 500 micrograms/ml AA in whole b
Health care workers at risk. An interview with Patricia Wetzel, MD [interview]: Asepsis. 1995 1ST-2ND QUART;17(1):10-3. Unique Identifier : AIDSLINE MED/95344689; Wetzel P
PCR-ligation-PCR mutagenesis: a protocol for creating gene fusions and mutations.: Biotechniques. 1995 May;18(5):746-50. Unique Identifier : AIDSLINE MED/95344713; Ali SA; Steinkasserer A; SANDOZ Research Institute Vienna, Austria.
Infections and immunological hazards of allogeneic bone transplantation.: Arch Orthop Trauma Surg. 1995;114(3):159-66. Unique Identifier : AIDSLINE MED/95344898; Hofmann GO; Kirschner MH; Wangemann T; Falk C; Mempel W; Hammer C; Chirurgische Klinik und Poliklinik,; Ludwig-Maximilians-Universitat, Klinikum Grosshadern, Munchen,; Germany.; Allogeneic transplantation of human cancellous and cortical bone is a controversially discussed concept in trauma and orthopaedic surgery. Biological and immunological arguments support transplantation of autologous material whenever this is technically possible. On the other hand, synthetic alloplastic materials for
Differences in perception of risk for HIV infection with steady and non-steady partners among homosexual men.: AIDS Educ Prev. 1995 Apr;7(2):103-15. Unique Identifier : AIDSLINE MED/95344902; Bosga MB; de Wit JB; de Vroome EM; Houweling H; Schop W; Sandfort TG; Department of Social and Organizational Psychology, Utrecht; University, The Netherlands.; In this study it was assessed whether homosexual men who practiced unprotected anogenital intercourse with steady and non-steady partners subjectively perceived their behaviors to be risky. Data were collected from 165 homosexual participants in an ongoing cohort study who reported unprotected anal sex. A variety of p
Self-disclosure of HIV-1 antibody test results: the San Francisco General Hospital Cohort.: AIDS Educ Prev. 1995 Apr;7(2):116-23. Unique Identifier : AIDSLINE MED/95344903; Stempel RR; Moulton JM; Moss AR; Department of Public Health, Florida International University,; North Miami 33181, USA.; We followed 93 subjects from the San Francisco General Hospital Cohort for one year after notifying them of their HIV-1 antibody test results in order to examine self-disclosure, reactions, and concerns regarding disclosure. By one year post-notification, 92% of gay friends, 82% of primary sexual partners, 56% of new
AIDS education intervention utilizing a person with AIDS: examination and clarification.: AIDS Educ Prev. 1995 Apr;7(2):124-33. Unique Identifier : AIDSLINE MED/95344904; Dennehy EB; Edwards CA; Keller RL; Department of Psychology, University of North Carolina at; Wilmington 28403, USA.; The utility of a person with AIDS (PWA) in conveying AIDS information to college students is assessed. Mode of transmission of HIV is proposed to serve as a moderating variable in students receptivity to the AIDS information and perception of the source of AIDS information. Two-hundred-sixty undergraduate students re
Development and evaluation of an HIV-risk reduction program for female college students.: AIDS Educ Prev. 1995 Apr;7(2):145-59. Unique Identifier : AIDSLINE MED/95344906; Sikkema KJ; Winett RA; Lombard DN; Center for AIDS Intervention Research (CAIR), Medical College of; Wisconsin, Milwaukee, USA.; College students are engaging in high rates of behavior related to risk of infection from Human Immunodeficiency Virus (HIV) and other sexually transmitted diseases (STDs). A cognitive-behavioral skills training program for heterosexual college females focused on sexual assertiveness skills and the reduction of risk-r
Development of a culturally, theoretically and developmentally based survey instrument for assessing risk behaviors among African-American early adolescents living in urban low-income neighborhoods.: AIDS Educ Prev. 1995 Apr;7(2):160-77. Unique Identifier : AIDSLINE MED/95344907; Stanton B; Black M; Feigelman S; Ricardo I; Galbraith J; Li X; Kaljee L; Keane V; Nesbitt R; Department of Pediatrics, University of Maryland, Baltimore; 21201, USA.; The creation of developmentally and culturally appropriate data-gathering instruments is necessary as health researchers and interventionists expand their investigations to community-based minority adolescent populations. The creation of such instruments is a complex process, requiring the integration of multiple data
Use of ethnography in the evaluation and targeting of HIV/AIDS education among Latino farm workers.: AIDS Educ Prev. 1995 Apr;7(2):178-91. Unique Identifier : AIDSLINE MED/95344908; Bletzer KV; Comprehensive Drug Research Center, University of Miami School of; Medicine, FL 33136, USA.; Ethnography can be utilized to assess the impact of HIV/AIDS education simultaneous with the implementation of program activities. An ethnographic analysis based on field methods adapted in a Michigan program that targets migrant farmworkers highlights responses to showings of a bilingual AIDS education video; the thi
Barrier contraception: issues and trends (continuing education credit).: Nurs Stand. 1995 Jun 14-20;9(38 Suppl Nu):3-8; quiz 10-2. Unique Identifier : AIDSLINE MED/95344947; Wootton G
Studies on the intermolecular forces involved in the antibody-antigen interactions, using V3 synthetic peptides and sera from HIV1 seropositive patients.: Rev Roum Virol. 1994 Jul-Dec;45(3-4):143-57. Unique Identifier : AIDSLINE MED/95345002; Magureanu CG; Diaconu C; Alexandrescu R; Tirdei G; Cernescu C; Stefan S. Nicolau Institute of Virology, Bucharest, Romania.; The nature of physical forces responsible for the antibody-antigen (Ab-Ag) reaction was analyzed in an original system, represented by synthetic peptides derived from the V3 consensus sequences of some HIV1 subtypes gp 120 and HIV1 positive human serum. For locating antigenic determines, flexibility, hydrophilicity an
Syncytium forming capacity of HIV 1 strains in inhibited by pretreatment of CD4 expressing cells with 3'-azido-3'-deoxythymidine but not by alpha interferon.: Rev Roum Virol. 1994 Jul-Dec;45(3-4):171-83. Unique Identifier : AIDSLINE MED/95345004; Ruta SM; Cernescu C; Stefan S. Nicolau Institute of Virology, Bucharest, Romania.; 3 azido-3 deoxythymidine ( AZT ) inhibits the ability of uninfected CD4 expressing cells to participate in syncytium formation, when cocultured with cells chronically infected with human immunodeficiency virus type 1 (HIV 1). The inhibition of giant cel
CD 26--to be or not to be a cofactor for CD 4 receptor of human immunodeficiency viruses.: Rev Roum Virol. 1994 Jul-Dec;45(3-4):203-9. Unique Identifier : AIDSLINE MED/95345007; Popescu A; Cernescu C; Stefan S. Nicolau Institute of Virology, Bucharest, Romania.; Earlier work has shown that HIV binding to CD 4 is necessary, but apparently not sufficient, for viral entry into cells. Several molecules have been proposed as potential candidates for coreceptors in HIV infection. Remarkable attention and criticism was raised by the report of Hovanessian group from Pasteur Institute
Epidemic HIV-related Kaposi's sarcoma: a retrospective analysis and validation of TIS staging. GICAT. Gruppo Italiano Collaborativo AIDS e Tumori.: Ann Oncol. 1995 Apr;6(4):383-7. Unique Identifier : AIDSLINE MED/95345020; Tambussi G; Repetto L; Torri V; Saracco A; Moresco L; Antinori A; Zerboni R; Lazzarin A; Department of Infectious Diseases, Mario Negri Institute, Milan,; Italy.; BACKGROUND: We wished to assess the clinical value in terms of treatment choice and establishment of the prognosis of the ACTG classification modified (TNM-TIS) according to the recent guidelines of CDC for the classification of the HIV infection in patients with HIV-related epidemic Kaposi s sarcoma (EKS). PATIENTS:
AIDS' Impact conference.: AIDS Care. 1995;7(2):S3-4. Unique Identifier : AIDSLINE MED/95345139; Hedge B; Catalan J; Sherr L; St. Bartholomew's Hospital, London, UK.
HIV counselling and testing: research and policy issues.: AIDS Care. 1995;7(2):115-24. Unique Identifier : AIDSLINE MED/95345140; Phillips KA; Coates TJ; Department of General Internal Medicine, University of; California, San Francisco 94105, USA.; The research and policy issues pertaining to HIV counselling and testing (C&T) have evolved since 1985, when a test to detect HIV antibodies first became available. In this paper we examine current and future research and policy issues relevant to C&T. We divide our discussion into three general areas which pro
Testing patients for HIV before surgery: the views of doctors performing surgery.: AIDS Care. 1995;7(2):125-8. Unique Identifier : AIDSLINE MED/95345141; Chapman K; Meadows J; Catalan J; Gazzard B; Department of Psychological Medicine, Charing Cross and; Westminster Medical School, London, UK.; The aim of this study was to investigate the attitudes of doctors performing surgery to the HIV antibody testing of surgical patients. Fifty of eighty (62.5%) doctors performing surgery who are working in two London teaching hospitals returned completed anonymous postal questionnaires. Sixty-six per cent of the sample
Antenatal testing for HIV antibody: problems of documentation and record.: AIDS Care. 1995;7(2):129-33. Unique Identifier : AIDSLINE MED/95345142; Dalzell F; Farkas AG; Hawken J; Hudson CN; Department of Obstetrics and Gynaecology, St Bartholomew's; Hospital (Homerton), London, UK.; The objective of this study was to audit an ante-natal HIV screening programme by observing the congruence of documentation of consent between case notes and request forms; correlation of testing with prior agreement to be tested; and recording documentation that the test had been offered but declined in women who wer
Is HIV testing in antenatal clinics worthwhile? Can we afford it?: AIDS Care. 1995;7(2):135-42; discussion 143-5. Unique Identifier : AIDSLINE MED/95345143; Chrystie IL; Zander L; Tilzey A; Wolfe CD; Kenney A; Banatvala JE; Department of Virology, United Medical School of Guy's and St; Thomas's, London, UK.; Since 0.2-0.4% of pregnant women attending antenatal clinics (ANC) at St Thomas s Hospital are HIV positive, and as the Department of Health (DH) have recommended that universal voluntary HIV testing be made available to women attending ANC in areas of known or suspected higher prevalence of HIV infection, we examined
'Going public' and 'watching sick people'--the clinic setting as a factor in the experiences of gay men participating in AIDS clinical trials.: AIDS Care. 1995;7(2):147-58. Unique Identifier : AIDSLINE MED/95345144; Ryan L; Department of Sociology, University of Kent, Canterbury, UK.; This paper reports findings from a study which was concerned to investigate the experiences of gay men living with HIV disease on anti-HIV clinical drug trials in Australia . Participation observation of a Phase 1 clinical trial and in-depth interviews with both trial participant
Concern, perceived risk and attitudes towards HIV/AIDS in Scottish prisons.: AIDS Care. 1995;7(2):159-70. Unique Identifier : AIDSLINE MED/95345145; McKee KJ; Markova I; Power KG; Department of Psychology, University of Stirling, UK.; Four hundred and eighty male prisoners and 500 male staff from 7 Scottish prisons took part in a study assessing perception of risk and attitudes towards HIV/AIDS. Prison staff were found to perceive prison as a higher-risk environment for HIV/AIDS than outside prison, whereas prisoners perceived the opposite. Prisone
Preference for sex on amphetamine: a marker for HIV risk behaviour among male intravenous amphetamine users in Stockholm.: AIDS Care. 1995;7(2):171-88. Unique Identifier : AIDSLINE MED/95345146; Kall K; Nilsonne A; Department of Psychiatry, Karolinska Institute, St Gorans; Hospital, Stockholm, Sweden.; Two hundred injecting drug users at the Remand Prison in Stockholm participated in an interview study of sexual behaviour in parallel to an ongoing HIV epidemiological study. Fifty-four subjects were women and 146 were men. Amphetamine was the main drug used by 115 and heroin by 85. Twenty-six were HIV seropositive. S
Carers' burden and adjustment to HIV.: AIDS Care. 1995;7(2):189-203. Unique Identifier : AIDSLINE MED/95345147; Pakenham KI; Dadds MR; Terry DJ; University of Queensland, Australia.; Empirical evidence from well designed studies into the effects on carers of caring for a person with HIV is lacking. This study investigated the correlates of carers burden and adjustment to their caring for a person with HIV. Thirty-four carers and their HIV-infected patients were interviewed and completed self-admi
Beliefs about condoms in 12/13 and 16/17 year olds.: AIDS Care. 1995;7(2):205-10. Unique Identifier : AIDSLINE MED/95345148; Ogden J; Harden A; Department of General Practice, UMDS, London, UK.; The present study examined the beliefs and attitudes which surround condoms and their use. Qualitative data in the form of short essays were collected from 12/13 (n = 148) and 16/17 (n = 63) year olds. The results suggest that condoms are conceptualized in terms of a complex set of factual and evaluative factors such
A measure of knowledge and confidence in relation to HIV and AIDS: reliability and validity.: AIDS Care. 1995;7(2):211-28. Unique Identifier : AIDSLINE MED/95345149; Ferguson E; Cox T; Irving K; Leiter M; Farnsworth B; Department of Psychology, University of Nottingham, UK.; Knowledge of HIV and AIDS is widely seen as an important determinant of anxiety about such infection in health care workers. However, existing measures of this knowledge suffer from a number of methodological problems and few demonstrate adequate reliability and validity. This paper documents the development of a new
Acceptance of zidovudine (AZT) in early HIV disease: the role of health beliefs.: AIDS Care. 1995;7(2):229-5. Unique Identifier : AIDSLINE MED/95345150; Catt S; Stygall J; Catalan J; Academic Department of Psychiatry, Charing Cross & Westminster; Medical School, London, UK.; The object of this paper is to explore the health beliefs associated with taking AZT in asymptomatic HIV seropositive individuals. Twenty-eight asymptomatic gay men receiving out-patient care completed self-report questionnaires. Information was gathe
HIV agencies: can they evaluate their own services?: AIDS Care. 1995;7(2):237-42. Unique Identifier : AIDSLINE MED/95345151; Williamson L; McPhail K; Lewis R; Centre for HIV/AIDS and Drug Studies, City Hospital, Edinburgh,; Scotland.; This paper describes the development and implementation of self-evaluation methods and guidelines in non-statutory HIV agencies that have been funded by Lothian Health. Two researchers developed this work under the aegis of the Lothian Health Centre for HIV/AIDS and Drug Studies (CHADS). It was implemented in eight ag
World Health Organization global AIDS statistics.: AIDS Care. 1995;7(2):244-8. Unique Identifier : AIDSLINE MED/95345152
An analysis of the process of human immunodeficiency virus sexual risk behavior change.: Epidemiology. 1995 May;6(3):238-42. Unique Identifier : AIDSLINE MED/95345207; Blower SM; van Griensven GJ; Kaplan EH; Department of Epidemiology and Biostatistics, University of; California San Francisco, San Francisco General Hospital; 94143-1347, USA.; Few studies have tried to identify the process of risk behavior change. In this paper, we present a method for the analysis of the process of risk behavior change; the methodology involves using time series data to form transition probability matrices. We apply the method to human immunodeficiency virus (HIV) sexual r
HIV winners and losers.: Epidemiology. 1995 May;6(3):329-31. Unique Identifier : AIDSLINE MED/95345224; Frerichs RR; Department of Epidemiology, UCLA School of Public Health; 90095-1772, USA.
Antiretroviral therapy: reference guide to major clinical trials in patients infected with human immunodeficiency virus.: Clin Infect Dis. 1995 May;20(5):1145-51. Unique Identifier : AIDSLINE MED/95345277; Spooner KM; Lane HC; Masur H; Critical Care Medicine Department, Clinical Center, National; Institutes of Health, Bethesda, Maryland 20892, USA.
Pulmonary disease due to infection by Mycobacterium avium complex in patients with AIDS.: Clin Infect Dis. 1995 May;20(5):1186-94. Unique Identifier : AIDSLINE MED/95345285; Kalayjian RC; Toossi Z; Tomashefski JF Jr; Carey JT; Ross JA; Tomford JW; Blinkhorn RJ Jr; Department of Medicine, Case Western Reserve University School of; Medicine, MetroHealth Medical Center, Cleveland, Ohio 44109-1998,; USA.; We reviewed the clinical, radiographic, and histologic features of nine patients with AIDS and pulmonary disease due to Mycobacterium avium complex (MAC). Pulmonary MAC disease was defined by (1) the isolation of MAC from two or more lower respiratory tract specimens or from a single lung biopsy sample, (2) an infiltr
Disseminated acanthamoeba infection in patients with AIDS: case reports and review.: Clin Infect Dis. 1995 May;20(5):1207-16. Unique Identifier : AIDSLINE MED/95345288; Sison JP; Kemper CA; Loveless M; McShane D; Visvesvara GS; Deresinski SC; Department of Medicine, Stanford University School of Medicine,; California, USA.; Acanthamoeba infection has been described as an opportunistic infection in persons with AIDS. We report two cases of patients with AIDS and acanthamoeba infection and review the manifestations of this protozoan infection in patients infected with human immunodeficiency virus. The diagnosis of this infection requires a
Observations on the pathological spectrum and clinical course of microsporidiosis in men infected with the human immunodeficiency virus: follow-up study.: Clin Infect Dis. 1995 May;20(5):1229-35. Unique Identifier : AIDSLINE MED/95345290; Rabeneck L; Genta RM; Gyorkey F; Clarridge JE; Gyorkey P; Foote LW; V. A. Medical Center (111D), Houston, Texas 77030, USA.; The purposes of this research were to determine whether microsporidian infection is accompanied by structural alterations of the duodenal mucosa and to characterize the clinical and morphological evolution of intestinal microsporidiosis . In a previous systematic electr
An epidemiologic analysis of Mycobacterium avium complex disease in homosexual men infected with human immunodeficiency virus type 1.: Clin Infect Dis. 1995 May;20(5):1250-8. Unique Identifier : AIDSLINE MED/95345293; Hoover DR; Graham NM; Bacellar H; Murphy R; Visscher B; Anderson R; McArthur J; Johns Hopkins School of Hygiene and Public Health, Department of; Epidemiology, Baltimore, Maryland 21205, USA.; Cofactors associated with the Mycobacterium avium complex (MAC) disease and its prognosis in incident cases of AIDS in homosexuals were studied. We compared 51 men in whom MAC disease developed as the initial AIDS-defining illness (termed AIDS illness hereafter); 157 men who had MAC disease subsequent to another AIDS
Persistent coccidioidal seropositivity without clinical evidence of active coccidioidomycosis in patients infected with human immunodeficiency virus.: Clin Infect Dis. 1995 May;20(5):1281-5. Unique Identifier : AIDSLINE MED/95345298; Arguinchona HL; Ampel NM; Dols CL; Galgiani JN; Mohler MJ; Fish DG; Medical Service, Veterans Affairs Medical Center, Tucson, Arizona; 85723, USA.; We retrospectively identified 13 patients infected with human immunodeficiency virus (HIV) who had persistently positive coccidioidal serological tests without evidence of active coccidioidomycosis--to our knowledge, a heretofore undescribed phenomenon. The median duration of follow-up was 19 months. Five patients dev
The natural history of progressive multifocal leukoencephalopathy in patients with AIDS. Canadian PML Study Group.: Clin Infect Dis. 1995 May;20(5):1305-10. Unique Identifier : AIDSLINE MED/95345302; Fong IW; Toma E; St. Michael's Hospital, University of Toronto, Ontario, Canada.; Progressive multifocal leukoencephalopathy (PML) is usually a fatal neurological disease. The natural history of PML in patients with human immunodeficiency virus infection was analyzed. The correlations between CD4+ lymphocyte count, previous diagnosis of AIDS, treatment with cytarabine, and survival time are reporte
Effects of zidovudine use during pregnancy on resistance and vertical transmission of human immunodeficiency virus type 1.: Clin Infect Dis. 1995 May;20(5):1321-6. Unique Identifier : AIDSLINE MED/95345305; Frenkel LM; Wagner LE 2nd; Demeter LM; Dewhurst S; Coombs RW; Murante BL; Reichman RC; Department of Pediatrics, University of Rochester, New York, USA.; The resistance of human immunodeficiency virus type 1 (HIV-1) to zidovudine and the vertical transmission of the virus were assessed among all 62 HIV-1-infected pregnant women identified prior to delivery at one institution. HIV-1 was transmitted to infants from 11 (26%) of 42 women who did not receive oral zidovudine
Brain stem encephalitis due to varicella-zoster virus in a patient with AIDS.: Clin Infect Dis. 1995 May;20(5):1378-80. Unique Identifier : AIDSLINE MED/95345313; Moulignier A; Pialoux G; Dega H; Dupont B; Huerre M; Baudrimont M; Service de Neurologie, Hopital Tenon, Paris, France.; We describe a patient infected with human immunodeficiency virus (HIV) who had localized brain stem encephalitis due to varicella-zoster virus (VZV) and no cutaneous eruption. Diagnosis of the infection was based on the presence of Cowdry type A intranuclear inclusions in neurons, astrocytes, and oligodendrocytes posi
Cryptococcal empyema: case report and review.: Clin Infect Dis. 1995 May;20(5):1396-8. Unique Identifier : AIDSLINE MED/95345319; Mulanovich VE; Dismukes WE; Markowitz N; Division of Infectious Diseases, University of Alabama at; Birmingham, USA.; A 28-year-old male infected with the human immunodeficiency virus (HIV) developed a pleural empyema caused by Cryptococcus neoformans. He responded well to chest-tube drainage and antifungal therapy; he received fluconazole as maintenance therapy for 1 year and has not relapsed. We reviewed the English-language litera
Mycobacterium xenopi infection masquerading as pulmonary tuberculosis in two patients infected with the human immunodeficiency virus.: Clin Infect Dis. 1995 May;20(5):1399-401. Unique Identifier : AIDSLINE MED/95345320; Jacoby HM; Jiva TM; Kaminski DA; Weymouth LA; Portmore AC; Division of Infectious Diseases, University of Rochester Medical; Center, New York, USA.; Mycobacterium xenopi infections have rarely been reported among patients infected with the human immunodeficiency virus (HIV). We recently treated two HIV-infected men, neither of whom had a history of pulmonary disease or AIDS-defining conditions, and who had M. xenopi lung infections. Both patients presented with ni
Primary Mycobacterium avium complex septic arthritis in a patient with AIDS [letter]: Clin Infect Dis. 1995 May;20(5):1432-4. Unique Identifier : AIDSLINE MED/95345330; Disla E; Reddy A; Cuppari G; Mullen M
Trimethoprim-sulfamethoxazole-induced renal tubular acidosis in a patient with AIDS [letter]: Clin Infect Dis. 1995 May;20(5):1435-7. Unique Identifier : AIDSLINE MED/95345332; Domingo P; Ferrer S; Cruz J; Morla R; Ris J
[The demand for emergency medical care by the prison population]: An Med Interna. 1995 Apr;12(4):175-81. Unique Identifier : AIDSLINE MED/95345353; Miret C; Miro O; Pedrol E; Gomez-Angelats E; Casademont J; Camp J; Milla J; Urbano-Marquez A; Servicio de Medicina Interna General, Hospital Clinic i; Provincial, Barcelona.; BACKGROUND: Urgent medical claim from recluse population shows some special traits due to firstly, the reclusion situation itself and the high prevalence of certain diseases in this population, as the infections ones, such as HIV infection, hepatitis B and tuberculosis. Moreover, emergency rooms constitute for this pa
[Syphilitic general paralysis in a young patient (letter)]: An Med Interna. 1995 Apr;12(4):204. Unique Identifier : AIDSLINE MED/95345364; Zapater Hernandez P; Alba Martin D; Archilla Esteban J; Molina Gomez F
Recovery of human immunodeficiency virus from peritoneal dialysis effluent.: J Am Soc Nephrol. 1995 May;5(11):1926-9. Unique Identifier : AIDSLINE MED/95345382; Scheel PJ Jr; Farzadegan H; Ford D; Malan M; Watson A; Department of Medicine, The Johns Hopkins Medical Institutions,; Baltimore, MD, USA.; Increasing numbers of HIV-infected patients who have ESRD are being treated with continuous ambulatory peritoneal dialysis (CAPD). To investigate the potential infectious nature of peritoneal dialysate (PD), the peritoneal dialysis effluent was studied in 14 patients on CAPD who were known to be HIV antibody positive.
Human immunodeficiency virus-type 1 replication can be increased in peripheral blood of seropositive patients after influenza vaccination.: Blood. 1995 Aug 1;86(3):1082-9. Unique Identifier : AIDSLINE MED/95345458; O'Brien WA; Grovit-Ferbas K; Namazi A; Ovcak-Derzic S; Wang HJ; Park J; Yeramian C; Mao SH; Zack JA; Veterans Affairs Medical Center, Department of Medicine, West Los; Angeles, CA, USA.; Despite considerable evidence that cell activation enhances human immunodeficiency virus-type 1 (HIV-1) replication in vitro, there is very little data on the role of immune activation on in vivo HIV-1 replication. In this study, we examined the effect of influenza vaccination on HIV-1 replication in the peripheral bl
Molecular analysis of clonality in Castleman's disease.: Blood. 1995 Aug 1;86(3):1131-8. Unique Identifier : AIDSLINE MED/95345464; Soulier J; Grollet L; Oksenhendler E; Miclea JM; Cacoub P; Baruchel A; Brice P; Clauvel JP; d'Agay MF; Raphael M; et al; Laboratoire d'Hematologie Moleculaire, Hopital de Jour; Hematologie-Oncologie, Paris, France.; Castleman s disease (CD) is a rare atypical lymphoproliferative disorder that is morphologically and clinically heterogenous and is associated with a risk of developing malignant lymphoma. We report the clonality status of CD tissues in 34 patients, including 14 patients infected by the human immunodeficiency virus (H
Proteinaceous (angiocentric sclerosing) lymphadenopathy: a polyclonal systemic, nonamyloid deposition disorder.: Blood. 1995 Aug 1;86(3):1159-62. Unique Identifier : AIDSLINE MED/95345467; Michaeli J; Niesvizky R; Siegel D; Ladanyi M; Lieberman PH; Filippa DA; Division of Hematologic Oncology, Memorial Sloan-Kettering Cancer; Center, New York, NY 10021, USA.; Proteinaceous lymphadenopathy with hypergammaglobulinemia (PLWH) is an exceedingly rare disease of unknown etiology. Described primarily as a pathologic entity, relatively little is known about its clinical manifestations or its response to therapy. The disease is often referred to and treated as an unusual form of pl
Synergistic effect of cortisol and HIV-1 envelope peptide on the NK activities of normal lymphocytes.: Brain Behav Immun. 1995 Mar;9(1):20-30. Unique Identifier : AIDSLINE MED/95345520; Nair MP; Schwartz SA; State University of New York at Buffalo, USA.; In order to examine the potential role of stress hormones and circulating HIV-1-derived products in the progression of HIV infections, we developed an in vitro model system that investigates the effects of cortisol and HIV soluble gene products on the natural killer cell activity of normal lymphocytes. The system empl
[Epidemiology of HIV in Germany]: Gesundheitswesen. 1995 May;57(5):291-8. Unique Identifier : AIDSLINE MED/95345607; Wittkowski KM; Institut fur Medizinische Biometrie der; Eberhard-Karls-Universitat Tubingen.; In many developing countries, HIV is predominantly distributed among heterosexuals. This has given rise to the concern that similar patterns are to be expected in Europe. The current publication discusses different methods for estimation of the number of people infected. The figures published for the first time 1988-1
Strain-dependent migration of CD4 and CD8 lymphocyte subsets to lymph nodes in NOD (nonobese diabetic) and control mice.: Dev Immunol. 1994;3(4):273-82. Unique Identifier : AIDSLINE MED/95345683; Faveeuw C; Gagnerault MC; Lepault F; CNRS URA 1461, Hopital Necker, Paris, France.; Subpopulations of lymphoid cells were compared with respect to their ability to migrate into peripheral lymphoid organs of nonobese diabetic (NOD) mice and various strains of control mice. In short-term, in vivo homing studies, no major differences in the pattern of homing of B and T cells were observed among all mous
Quantitative analysis of the efficiency of clonal deletion in the thymus.: Dev Immunol. 1994;4(1):43-53. Unique Identifier : AIDSLINE MED/95345689; Spain LM; Berg LJ; Department of Cellular and Developmental Biology, Harvard; University, Cambridge, Massachusetts 02138, USA.; One of the major mechanisms for establishing self-tolerance is the clonal deletion of self-reactive T cells during their development in the thymus. Using a TCR transgenic mouse model, we have established a quantitative ex vivo assay for examining the sensitivity and specificity of negative selection. Thymic organ cult
Encephalitozoon cuniculi isolated from the urine of an AIDS patient, which differs from canine and murine isolates.: J Eukaryot Microbiol. 1995 Jul-Aug;42(4):367-72. Unique Identifier : AIDSLINE MED/95345842; Hollister WS; Canning EU; Colbourn NI; Aarons EJ; Department of Biology, Imperial College of Science, Technology &; Medicine, London, United Kingdom.; A species of Encephalitozoon has been isolated from the urine of a patient with the acquired immunodeficiency syndrome and maintained in vitro in Madin Darby Canine Kidney cells. When examined by random amplified polymorphic DNA polymerase chain reaction the new isolate was found to differ from E. hellem and to have a
Perinatal transmission of HIV.: Midwifery Today Childbirth Educ. 1994 Winter;(32):43. Unique Identifier : AIDSLINE MED/95345891; Edmunds J
HIV-1 coat protein gp120-induced increases in levels of intrasynaptosomal calcium.: Brain Res. 1995 Apr 24;678(1-2):200-6. Unique Identifier : AIDSLINE MED/95346297; Nath A; Padua RA; Geiger JD; Department of Medical Microbiology, University of Manitoba; Faculty of Medicine, Winnipeg, Canada.; The effects of human immunodeficiency virus type-1 (HIV-1) coat protein gp120 on levels of intrasynaptosomal calcium ([Ca2+]i) were determined in rat cortical synaptosomes. gp120 at concentrations of > or = 400 pM, significantly (P
Increased reliability of selective PCR by using additionally mutated primers and a commercial Taq DNA polymerase enhancer.: Mol Biotechnol. 1995 Apr;3(2):166-9. Unique Identifier : AIDSLINE MED/95346400; De Milito A; Catucci M; Iannelli F; Romano L; Zazzi M; Valensin PE; Dipartimento di Biologia Molecolare, Universita di Siena, Italy.; A reliable selective PCR procedure that combines the use of additionally mutated primers with the specificity-enhancing properties of a commercial preparation (Perfect Match, Stratagene) is described. The human immunodeficiency virus type 1 pol gene point mutations known to confer in vitro resistance to azidothymidine
Accurate determination of DNA in agarose gels using the novel algorithm GelScann(1.0).: Comput Appl Biosci. 1995 Apr;11(2):187-94. Unique Identifier : AIDSLINE MED/95346415; Metzker ML; Allain KM; Gibbs RA; Department of Molecular and Human Genetics, Baylor College of; Medicine, Houston, TX 77030, USA.; GelScann(1.0) is a user-friendly program that accurately quantitates DNA from CCD imaged agarose gels. The algorithm automatically locates lanes, locates bands within a given lane, and quantitates the intensity of each band. GelScann (1.0) uses a statistical method to discriminate DNA from local background fluorescenc
Oral histoplasmosis in HIV-infected patients. A report of two cases.: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Jun;79(6):710-4. Unique Identifier : AIDSLINE MED/95346458; Chinn H; Chernoff DN; Migliorati CA; Silverman S Jr; Green TL; Division of Oral Medicine, UCSF, USA.; Histoplasmosis is a fungal infection caused by the organism Histoplasma capsulatum. Disseminated disease usually occurs in immunosuppressed patients or in patients with chronic illnesses. Although relatively uncommon, histoplasmosis has been reported in patients with AIDS, and oral lesions have been noted on multiple
Epidermal Langerhans' cells and their function in the skin immune system.: Ann Allergy Asthma Immunol. 1995 Jul;75(1):5-10; quiz 10-2. Unique Identifier : AIDSLINE MED/95346491; Hogan AD; Burks AW; Department of Pediatrics, Arkansas Children's Hospital,; University of Arkansas for Medical Science, Little Rock, USA.; OBJECTIVE: This article reviews the role of the epidermal Langerhans cell in contact dermatitis and atopic dermatitis. Included in this review are sections on the historical, morphologic, immunohistochemical, and electron microscopic aspects of the Langerhans cell. Differences between freshly isolated and cultured L
Specific immunity to Listeria monocytogenes in the absence of IFN gamma.: Immunity. 1995 Jul;3(1):109-17. Unique Identifier : AIDSLINE MED/95346501; Harty JT; Bevan MJ; Department of Microbiology, University of Iowa, Iowa City 52242,; USA.; Cytokine and cytokine receptor gene knockout mice provide powerful experimental systems to characterize the functions of these molecules in resistance to infectious disease. Such mice may also provide unique models of immune deficiency to learn whether manipulation of the immune response can overcome the specific dysf
HIV Tat represses transcription through Sp1-like elements in the basal promoter.: Immunity. 1995 Jul;3(1):127-38. Unique Identifier : AIDSLINE MED/95346503; Howcroft TK; Palmer LA; Brown J; Rellahan B; Kashanchi F; Brady JN; Singer DS; Experimental Immunology Branch, National Cancer Institute,; National Institutes of Health, Bethesda, MD 20892, USA.; MHC class I genes are potently repressed by HIV Tat, which transactivates the HIV LTR. Tat represses class I transcription by binding to complexes associated with a novel promoter element, consisting of Sp1-like DNA binding sites. Transcription by other Sp1-dependent promoters, such as MDR1 and the minimal SV40 promot
Strong agonist ligands for the T cell receptor do not mediate positive selection of functional CD8+ T cells.: Immunity. 1995 Jul;3(1):79-86. Unique Identifier : AIDSLINE MED/95346512; Hogquist KA; Jameson SC; Bevan MJ; Howard Hughes Medical Institute, Department of Immunology,; University of Washington, Seattle 98195, USA.; Positive selection of functional CD8+ T cells expressing an MHC class I-restricted T cell receptor can be induced in fetal thymus organ culture by class I-binding peptides related to the antigenic peptide ligand. Peptides that act as antagonist or weak agonist/antagonist ligands for mature T cells work efficiently in
Good communication--moving towards a changing childbirth objective.: Midwives. 1994 Nov;107(1282):414-5. Unique Identifier : AIDSLINE MED/95346556; MacKeith N
A public health approach to emergency medicine: preparing for the twenty-first century [see comments]: Acad Emerg Med. 1994 May-Jun;1(3):277-86. Unique Identifier : AIDSLINE MED/95346659; Bernstein E; Goldfrank LR; Kellerman AL; Hargarten SW; Jui J; Fish SS; Herbert BH; Flores C; Caravati ME; Krishel S; et al; Department of Emergency Medicine, University Medical Center,; Boston City Hospital, Boston, USA.; This paper focuses on the implications of an inadequate public health/preventive health care system for emergency medicine (EM), the role that EM providers can play in remedying critical health problems, and the benefits gained from a public health approach to EM. A broad definition of public health is adopted, sugges
Antisense approaches to cancer gene therapy.: Cancer Gene Ther. 1995 Mar;2(1):47-59. Unique Identifier : AIDSLINE MED/95346705; Mercola D; Cohen JS; San Diego Regional Cancer Center, CA 92121, USA.; Recent advances in the use of oligodeoxynucleotide and plasmid-derived RNA as antisense agents of special relevance to cancer gene therapy are summarized with emphasis on agents and systems which have lead to clinical trials and/or regression of established tumors in animal model systems. Transformed cell lines bearin
[Endoscopic gastrointestinal findings in patients with human immunodeficiency virus infection]: Gastroenterol Hepatol. 1995 Feb;18(2):57-60. Unique Identifier : AIDSLINE MED/95346727; Nieto I; Llach J; Bordas JM; Mondelo F; Elizalde I; Bataller R; Teres J; Servicios de Gastroenterologia, Hospital Clinic i Provincial,; Barcelona.; From January 1992 to August 1993, 150 endoscopies (114 fiber gastroscopies, 29 fiber colonoscopies and 7 CPRE) were carried out in a total of 142 anti HIV positive patients. The most frequent clinical manifestations leading to the exploration were dysphagia, epigastric pain, diarrhea and upper or lower gastrointestina
[Concepts of AIDS in relation to health and illness in homosexual men living in Quebec with AIDS]: Can J Nurs Res. 1995 Spring;27(1):57-75. Unique Identifier : AIDSLINE MED/95346830; Bellavance M; Perreault M; Herzlich s (1969) theoretical framework was used to explore Acquired Immune Deficiency Syndrome (AIDS) from the point of view of affected individuals. Content analysis was performed on transcripts of interviews with eight French Canadian gay men living with AIDS. Results indicate that health and illness are socially c
Tuberculosis in the AIDS era.: Clin Microbiol Rev. 1995 Apr;8(2):180-99. Unique Identifier : AIDSLINE MED/95346868; Sepkowitz KA; Raffalli J; Riley L; Kiehn TE; Armstrong D; Infectious Disease Service, Memorial Sloan-Kettering Cancer; Center, New York, NY 10021, USA.; A resurgence of tuberculosis has occurred in recent years in the United States and abroad. Deteriorating public health services, increasing numbers of immigrants from countries of endemicity, and coinfection with the human immunodeficiency virus (HIV) have contributed to the rise in th
Virus receptors: implications for pathogenesis and the design of antiviral agents.: Clin Microbiol Rev. 1995 Apr;8(2):293-315. Unique Identifier : AIDSLINE MED/95346873; Norkin LC; Department of Microbiology, University of Massachusetts, Amherst; 01003, USA.; A virus initiates infection by attaching to its specific receptor on the surface of a susceptible host cell. This prepares the way for the virus to enter the cell. Consequently, the expression of the receptor on specific cells and tissues of the host is a major determinant of the route of entry of the virus into the h
Cytokine regulation of HIV-1 LTR transactivation in human hepatocellular carcinoma cell lines.: Cancer Lett. 1995 Jul 20;94(1):41-8. Unique Identifier : AIDSLINE MED/95346915; Hsu ML; Chen SW; Lin KH; Liao SK; Chang KS; Graduate Institute of Clinical Medicine, Chang Gung Medical; College, Taoyuan-Hsien, Taiwan, Republic of China.; Human hepatocellular carcinoma (HCC) cell lines, HEP-G2, J5, and SK-HEP-1, which differ in their differentiation status, were compared for their trans-activating activities after treatment with cytokines or 12-O-tetradecanoylphorbol-13-acetate (TPA). These cells were transfected with a long terminal repeat (LTR) which
Inhibition of gene expression with ribozymes.: Cell Mol Neurobiol. 1994 Oct;14(5):523-38. Unique Identifier : AIDSLINE MED/95346988; Marschall P; Thomson JB; Eckstein F; Max-Planck-Institut fur Experimentelle Medizin, Gottingen,; Germany.; 1. Ribozymes can be designed to cleave in trans, i.e. several substrate molecules can be turned over by one molecule of the catalytic RNA. Only small molecular weight ribozymes, or small ribozymes, are discussed in this review with particular emphasis on the hammerhead ribozyme as this has been most widely used for th
Decreased cervicovaginal production of both IgA1 and IgA2 subclasses in women with AIDS.: Clin Exp Immunol. 1995 Jul;101(1):100-6. Unique Identifier : AIDSLINE MED/95347060; Belec L; Meillet D; Gaillard O; Prazuck T; Michel E; Ngondi Ekome J; Pillot J; Unite d'Immunologie Microbienne, Institut Pasteur, Paris,; France.; Paired sera and cervicovaginal secretions from 35 HIV-1-infected women representing different CDC stages of HIV infection were evaluated for total IgA, IgA1 and IgA2, for IgA, IgA1 and IgA2 to gp160, and for albumin. Age-matched healthy women (n = 45) served as controls. The secretion rates of total IgA, IgA1 and IgA2
Identification of HIV protein-derived cytotoxic T lymphocyte (CTL) epitopes for their possible use as synthetic vaccine.: Clin Exp Immunol. 1995 Jul;101(1):107-13. Unique Identifier : AIDSLINE MED/95347061; Brander C; Pichler WJ; Corradin G; Institute of Immunology and Allergology, Inselspital, Bern,; Switzerland.; CTL are by far the most important defence mechanisms against viral infections, and many attempts have been undertaken to induce protective CTL in vivo. In order to identify CTL epitopes for their possible use as peptide-vaccine candidates, HIV proteins were screened for peptide sequences which (i) fulfil the binding m
Defects in antigen-driven lymphocyte responses in common variable immunodeficiency (CVID) are due to a reduction in the number of antigen-specific CD4+ T cells.: Clin Exp Immunol. 1995 Jul;101(1):82-8. Unique Identifier : AIDSLINE MED/95347087; Funauchi M; Farrant J; Moreno C; Webster AD; Department of Clinical Immunology, Royal Free Hospital School of; Medicine, London, UK.; T cells from patients with CVID have defects that may relate to the failure in vivo of B cell production of antibodies. Antigen-driven responses of T cells from CVID patients and normal subjects have been assessed by measuring DNA synthesis in vitro. Low density cells enriched for antigen-presenting dendritic cells we
Tetanus toxoid-specific T cell responses in severe combined immunodeficiency (SCID) mice reconstituted with human peripheral blood lymphocytes.: Clin Exp Immunol. 1995 Jul;101(1):94-9. Unique Identifier : AIDSLINE MED/95347089; Somasundaram R; Jacob L; Herlyn D; Wistar Institute, Philadelphia, PA 19104, USA.; SCID mice reconstituted with human peripheral blood lymphocytes (PBL) have repeatedly been shown to produce antigen-specific B cell responses. We have derived tetanus toxoid (TT)-specific human T cell lines from cells of the peritoneal cavity, spleen and lymph nodes of SCID mice reconstituted with human PBL and booste
Fine-needle aspiration diagnosis of extrapulmonary Pneumocystis carinii lymphadenitis in a human immunodeficiency virus positive patient.: Diagn Cytopathol. 1995 May;12(3):251-3. Unique Identifier : AIDSLINE MED/95347220; Ellison E; Yuen SY; Lawson L; Chan NH; Department of Pathology and Medicine, St. Paul's Hospital,; University of British Columbia, Vancouver, Canada.; Extrapulmonary Pneumocystitis carinii is an uncommon and probably underdiagnosed complication of pulmonary P. carinii infections. We report the cytologic diagnosis of a case of P. carinii lymphadenitis which presented, without concurrent or historical pneumonitis, in a human immunodeficiency virus (HIV) positive patie
Induction of the increased Fyn kinase activity in anergic T helper type 1 clones requires calcium and protein synthesis and is sensitive to cyclosporin A.: Eur J Immunol. 1995 Jul;25(7):1836-42. Unique Identifier : AIDSLINE MED/95347378; Gajewski TF; Fields P; Fitch FW; Department of Pathology, Ben May Institute, University of; Chicago, IL 60637, USA.; Several alterations in T cell receptor-associated signal transduction have been observed following induction of anergy of T helper type 1 (Th1) clones, including a modified intracellular free calcium ([Ca2+]i) response and increased kinase activity associated with the protein tyrosine kinase p59fyn. In the current stu
Peripheral deletion of autoreactive CD8+ T cells in transgenic mice expressing H-2Kb in the liver.: Eur J Immunol. 1995 Jul;25(7):1932-42. Unique Identifier : AIDSLINE MED/95347392; Bertolino P; Heath WR; Hardy CL; Morahan G; Miller JF; Walter and Eliza Hall Institute of Medical Research, P.O. Royal; Melbourne Hospital, Victoria, Australia.; The response of T cells specific for liver antigens was examined in transgenic mice expressing the allogeneic major histocompatibility complex class I molecule H-2Kb (Kb) under the control of the sheep metallothionein promoter (Met-Kb mice). To follow the fate of Kb-specific T cells, and to prevent any aberrant thymic
Are CD8 T cells involved in control of African trypanosomiasis in a natural host environment?: Eur J Immunol. 1995 Jul;25(7):1965-71. Unique Identifier : AIDSLINE MED/95347396; Sileghem M; Naessens J; Trypanosomiasis Programme, International Livestock Research; Institute, Nairobi, Kenya.; Murine models have suggested that CD8 T cells might play a major parasite-promoting role in African trypanosomiasis. To assess the role of these cells in a natural host environment, we have depleted CD8 cells from Boran cattle in vivo and subsequently infected these animals with Trypanosoma congolense by tsetse fly ch
Self-reactive anti-class II T helper type 2 cell lines derived from gold salt-injected rats trigger B cell polycolonal activation and transfer autoimmunity in CD8-depleted normal syngeneic recipients.: Eur J Immunol. 1995 Jul;25(7):1972-9. Unique Identifier : AIDSLINE MED/95347397; Saoudi A; Castedo M; Nochy D; Mandet C; Pasquier R; Druet P; Pelletier L; INSERM U 28, Hopital Broussais, Paris, France.; Brown Norway (BN) rats given gold salts develop an autoimmune syndrome with an immune complex-type glomerulonephritis in the context of a polyclonal B cell activation that was suspected to be due to the emergence of anti-self major histocompatibility complex (MHC) class II T cells.
Differential contribution of the FcR gamma chain to the surface expression of the T cell receptor among T cells localized in epithelia: analysis of FcR gamma-deficient mice.: Eur J Immunol. 1995 Jul;25(7):2107-10. Unique Identifier : AIDSLINE MED/95347417; Park SY; Arase H; Wakizaka K; Hirayama N; Masaki S; Sato S; Ravetch JV; Saito T; Division of Molecular Genetics, Chiba University School of; Medicine, Japan.; The function of the Fc receptors gamma chain (FcR gamma) for the expression of the T cell receptor (TCR) complex and for T cell development, especially for T cells localized in epithelia, was investigated by analyzing FcR gamma-deficient mice. In wild-type mice, CD8 alpha alpha + beta -TCR alpha beta + T cells of inte
Interaction of avian sarcoma/leukemia viruses with heterologous hosts: inference for host-range and some pathogenic properties of human immunodeficiency viruses.: Folia Biol (Praha). 1995;41(1):1-14. Unique Identifier : AIDSLINE MED/95347505; Popovic M; Grofova M; Microbiology and Tumorbiology Center, Karolinska Institutet,; Stockholm, Sweden.; Although there are substantial differences between retroviruses originating from avian and primate species, a comparison of these two different biological systems reveals that interaction of these retroviruses with heterologous hosts involves similar biological principles. Retroviral isolates with high replicative cap
Intrathymic transplantation of islet antigen affects CD8+ diabetogenic T-cells resulting in tolerance to autoimmune IDDM.: Diabetes. 1995 Aug;44(8):871-7. Unique Identifier : AIDSLINE MED/95347531; Baumann EE; Buckingham F; Herold KC; Department of Pediatrics, University of Chicago, Illinois 60637,; USA.; The acquisition of T-cell tolerance in the thymus is limited to those antigens expressed in the thymus at the time of T-cell development. Normally, islet antigens that are involved in insulin-dependent diabetes mellitus (IDDM) are not present in the thymus, but we have previously shown that transplantation of islets e
Exercise and immunity [letter; comment]: Image J Nurs Sch. 1995 Summer;27(2):90. Unique Identifier : AIDSLINE MED/95347737; Groer M
The outer surface lipoprotein A of Borrelia burgdorferi provides direct and indirect augmenting/co-stimulatory signals for the activation of CD4+ and CD8+ T cells [corrected and republished in Immunol Lett 1995 Jun;46(3):137-42]: Immunol Lett. 1995 Feb;45(1-2):137-42. Unique Identifier : AIDSLINE MED/95347755; Simon MM; Nerz G; Kramer MD; Hurtenbach U; Schaible UE; Wallich R; Max-Planck-Institut fur Immunbiologie, Freiburg, Germany.; Naive CD4+ and CD8+ T cells require two distinct signals to proliferate and to express effector functions [1]. One is provided by the antigen receptor on the T cell (TCR) after its encounter with antigenic peptides associated with class I or II major histocompatibility complex (MHC) molecules on antigen-presenting cel
Outcome of infection with different strains of Trypanosoma cruzi in mice lacking CD4 and/or CD8.: Immunol Lett. 1995 Feb;45(1-2):53-60. Unique Identifier : AIDSLINE MED/95347764; Rottenberg ME; Riarte A; Sporrong L; Altcheh J; Petray P; Ruiz AM; Wigzell H; Orn A; Immunology Laboratory, Karolinska Institute, Stockholm, Sweden.; Mice lacking CD4 and/or CD8 gene expression, generated by embryonic stem-cell technology, were used to study the role of CD4+ and CD8+ cells in the resistance to the acute infection with virulent (Tulahuen and RA) or mild (CA-I) strains of Trypanosoma cruzi. The presence of both CD4+ and CD8+ cells contributed to the
Shigella infection induces cellular activation of T and B cells and distinct species-related changes in peripheral blood lymphocyte subsets during the course of the disease.: Infect Immun. 1995 Aug;63(8):2941-9. Unique Identifier : AIDSLINE MED/95347806; Islam D; Bardhan PK; Lindberg AA; Christensson B; Division of Clinical Bacteriology, Karolinska Institute, Huddinge; University Hospital, Sweden.; Immunophenotypic changes in peripheral blood lymphocytes (T, B, and NK cells) in patients during shigellosis was characterized by using triple-color flow cytometry. Eleven Shigella dysenteriae 1-infected adult patients (SDIP), 11 Shigella flexneri-infected adult patients (SFIP), 15 age- and sex-matched healthy control
Expansion of gamma delta+ T cells in BALB/c mice infected with Leishmania major is dependent upon Th2-type CD4+ T cells.: Infect Immun. 1995 Aug;63(8):3000-4. Unique Identifier : AIDSLINE MED/95347814; Rosat JP; Conceicao-Silva F; Waanders GA; Beermann F; Wilson A; Owen MJ; Hayday AC; Huang S; Aguet M; MacDonald HR; et al; World Health Organization Immunology Research and Training; Center, University of Lausanne, Epalinges, Switzerland.; T cells belong to either the alpha beta+ or gamma delta+ lineage as defined by their antigen receptor. Although both T-cell subsets have been shown to be involved in the immune response to the parasite Leishmania major, very little is known about possible interactions between these two populations. In this study, usin
Analysis of human monoclonal antibodies elicited by vaccination with a Cryptococcus neoformans glucuronoxylomannan capsular polysaccharide vaccine.: Infect Immun. 1995 Aug;63(8):3005-14. Unique Identifier : AIDSLINE GENBANK/U27190; Pirofski L; Lui R; DeShaw M; Kressel AB; Zhong Z; Department of Microbiology, Albert Einstein College of Medicine,; Bronx, New York 10461, USA.; The Cryptococcus neoformans capsular polysaccharide glucuronoxylomannan (GXM) has been conjugated to tetanus toxoid (GXM-TT) as an investigational vaccine. GXM-TT elicits antibodies that are protective in C. neoformans-infected mice. In an effort to characterize the fine specificity and molecular structure of human GX
Cytokine modulation alters pulmonary clearance of Rhodococcus equi and development of granulomatous pneumonia.: Infect Immun. 1995 Aug;63(8):3037-41. Unique Identifier : AIDSLINE MED/95347819; Kanaly ST; Hines SA; Palmer GH; Department of Veterinary Microbiology and Pathology, Washington; State University, Pullman 99164-7040, USA.; Rhodococcus equi, a facultative intracellular bacterium, causes chronic, often fatal granulomatous pneumonia in young horses and in humans with AIDS. The inability of host alveolar macrophages to kill intracellular R. equi results in the development of granulomas and progressive loss of pulmonary parenchyma. Clearance
Purification and characterization of a Shiga toxin A subunit-CD4 fusion protein cytotoxic to human immunodeficiency virus-infected cells.: Infect Immun. 1995 Aug;63(8):3073-8. Unique Identifier : AIDSLINE MED/95347825; al-Jaufy AY; King SR; Jackson MP; Department of Immunology and Microbiology, Wayne State University; School of Medicine, Detroit, Michigan 48201, USA.; In a previous paper, we reported that a chimeric toxin composed of the enzymatic domain of the Shiga toxin A polypeptide (StxA1) genetically fused to the human CD4 (hCD4) molecule selectively kills cells infected with human immunodeficiency virus type 1 (HIV-1). Although other hCD4-containing chimeras cytotoxic to HIV
T-cell cytokine responses in human infection with Mycobacterium tuberculosis.: Infect Immun. 1995 Aug;63(8):3231-4. Unique Identifier : AIDSLINE MED/95347850; Zhang M; Lin Y; Iyer DV; Gong J; Abrams JS; Barnes PF; Department of Medicine, University of Southern California School; of Medicine, Los Angeles 90033, USA.; Compared with healthy tuberculin reactors, Mycobacterium tuberculosis-stimulated peripheral blood mononuclear cells from tuberculosis patients had diminished production and mRNA expression of the Th1 cytokines gamma interferon and interleukin 2 ( IL-2 ), with no change i
Risks associated with long-term homelessness among women: battery, rape, and HIV infection.: Int J Health Serv. 1995;25(2):351-69. Unique Identifier : AIDSLINE MED/95347920; Fisher B; Hovell M; Hofstetter CR; Hough R; Center for Behavioral Epidemiology, La Mesa, CA 91941, USA.; The purposes of this study were to determine the prevalence of battery, rape, and HIV risk practices in a sample of long-term homeless women and to explore correlates of HIV risk practices. Fifty-three women who had been homeless for at least three months in the last year were interviewed at day and night shelters. Th
Modulation of immune function and cytokine production by various levels of vitamin E supplementation during murine AIDS.: Immunopharmacology. 1995 Apr;29(3):225-33. Unique Identifier : AIDSLINE MED/95347954; Wang Y; Huang DS; Wood S; Watson RR; Department of Family and Community Medicine, University of; Arizona, Tucson 85724, USA.; Female C57BL/6 mice were infected with LP-BM5 retrovirus, causing murine AIDS which is functionally similar to human AIDS. Dietary supplementation, with a 15-, 150- and 450-fold increase of vitamin E in a liquid diet, significantly restored levels of interleukin-2 (IL) and interferon-gamma produced by splenocytes, whi
Person and environment in HIV risk behavior change between adolescence and young adulthood.: Health Educ Q. 1995 May;22(2):211-26. Unique Identifier : AIDSLINE MED/95347992; Stiffman AR; Dore P; Cunningham RM; Earls F; George Warren Brown School of Social Work, Washington University,; St. Louis, MO 63130, USA.; This article explores how personal and environmental variables influence change in human immunodeficiency virus (HIV)-related risk behaviors between adolescence and young adulthood. Repeated interviews with 602 youths from 10 cities across the United States provide the data. These inte
Diffusion of AIDS curricula among Dutch secondary school teachers.: Health Educ Q. 1995 May;22(2):227-43. Unique Identifier : AIDSLINE MED/95347993; Paulussen T; Kok G; Schaalma H; Parcel GS; Dutch Center for Health Promotion and Health Education, Utrecht,; The Netherlands.; This study reports data from a sample of 698 Dutch secondary school teachers intending to provide classroom AIDS education. The study addresses determinants of awareness knowledge about and adoption of four nationally disseminated AIDS curricula. The results indicated that knowledge acquisition was largely dependent o
Calcium depletion from the endoplasmic reticulum activates the double-stranded RNA-dependent protein kinase (PKR) to inhibit protein synthesis.: J Biol Chem. 1995 Jul 14;270(28):16619-24. Unique Identifier : AIDSLINE MED/95348080; Srivastava SP; Davies MV; Kaufman RJ; Department of Biological Chemistry, University of Michigan; Medical Center, Ann Arbor 48105, USA.; Calcium depletion from the endoplasmic reticulum inhibits protein synthesis and correlates with increased phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (eIF-2 alpha) by a mechanism that does not require ongoing protein synthesis. To elucidate whether protein synthesis inhibition requires eIF-2
Preservation of surface-dependent properties of viral antigens following immobilization on particulate ceramic delivery vehicles.: J Biomed Mater Res. 1995 May;29(5):561-73. Unique Identifier : AIDSLINE MED/95348157; Kossovsky N; Gelman A; Sponsler E; Rajguru S; Torres M; Mena E; Ly K; Festekjian A; Department of Pathology, University of California, Los Angeles; School of Medicine 90024-1732, USA.; B-cell stimulation for the purpose of evoking an effective neutralizing humoral immune response is a surface phenomenon that is exquisitely specific to antigen conformation. Consequently, successful delivery of antigen, such as would be desired in a vaccine, entails preservation of an antigen s apparent native surface
Invasive Trichophyton rubrum infection in the immunocompromised host: report of three cases.: J Am Acad Dermatol. 1995 Aug;33(2 Pt 1):315-8. Unique Identifier : AIDSLINE MED/95348308; Grossman ME; Pappert AS; Garzon MC; Silvers DN; Department of Dermatology, Columbia-Presbyterian Medical Center,; New York, NY 10032, USA.
Differential diagnosis of CNS lesions in AIDS patients by FDG-PET.: J Comput Assist Tomogr. 1995 Jul-Aug;19(4):532-6. Unique Identifier : AIDSLINE MED/95348320; Villringer K; Jager H; Dichgans M; Ziegler S; Poppinger J; Herz M; Kruschke C; Minoshima S; Pfister HW; Schwaiger M; Department of Nuclear Medicine, Curatorium for Immunodeficiency,; Munich, Germany.; OBJECTIVE: The aim of this study was to evaluate the potential of FDG-PET in the differential diagnosis of CNS lesions in patients with AIDS, particularly to differentiate between toxoplasmosis and lymphoma. MATERIALS AND METHODS: We examined 11 AIDS patients, 6 with toxoplasmosis, 1 with a tuberculoma, and 4 with a p
Selective early increases of bronchoalveolar CD8+ lymphocytes in a LEW rat model of hypersensitivity pneumonitis.: J Allergy Clin Immunol. 1995 Jul;96(1):113-21. Unique Identifier : AIDSLINE MED/95348396; Richerson HB; Coon JD; Lubaroff D; Department of Internal Medicine, University of Iowa Hospitals,; Iowa City 52242-1081, USA.; BACKGROUND: The pathogenesis of hypersensitivity pneumonitis (HP) involves cell-mediated hypersensitivity; various bronchoalveolar T-cell subsets with uncertain roles in disease have been reported and implicated in the pathogenesis. OBJECTIVES: Previous studies at 72 hours after initial antigen challenges showed propo
Virus burden in long-term survivors of human immunodeficiency virus (HIV) infection is a determinant of anti-HIV CD8+ lymphocyte activity.: J Infect Dis. 1995 Aug;172(2):329-39. Unique Identifier : AIDSLINE MED/95348528; Ferbas J; Kaplan AH; Hausner MA; Hultin LE; Matud JL; Liu Z; Panicali DL; Nerng-Ho H; Detels R; Giorgi JV; Department of Medicine, School of Medicine, University of; California at Los Angeles, USA.; Persons infected with human immunodeficiency virus (HIV) for > 8 years were studied to delineate virologic and immunologic attributes of long-term survival. Whereas those with 300-700 CD4+ cells/microL often had circulating cytotoxic T lymphocytes (CTL) against HIV antigens, those with > 1000 CD4+ cells/microL did not
Antibody class and subclass responses to pneumococcal polysaccharides following immunization of human immunodeficiency virus-infected patients.: J Infect Dis. 1995 Aug;172(2):340-5. Unique Identifier : AIDSLINE MED/95348529; Carson PJ; Schut RL; Simpson ML; O'Brien J; Janoff EN; Department of Medicine, VA Medical Center, University of; Minnesota School of Medicine, Minneapolis, USA.; Antibodies of the IgM class and IgG2 and IgA2 subclasses are prominent in responses to pneumococcal polysaccharides (PPS) but may be decreased in human immunodeficiency virus (HIV)-infected patients, among whom invasive pneumococcal disease is common. After immunization of HIV-infected and -seronegative subjects with
Lack of association between acyclovir use and survival in patients with advanced human immunodeficiency virus disease treated with zidovudine. Zidovudine Epidemiology Study Group [see comments]: J Infect Dis. 1995 Aug;172(2):346-52. Unique Identifier : AIDSLINE MED/95348530; Gallant JE; Moore RD; Keruly J; Richman DD; Chaisson RE; Department of Medicine, Johns Hopkins University School of; Medicine, Baltimore, Maryland 21287-6220, USA.; To evaluate the association between acyclovir use and survival in patients with advanced human immunodeficiency virus infection, observational data from 1044 persons with AIDS or AIDS-related complex (ARC) and
Efficacy of antenatal zidovudine in reducing perinatal transmission of human immunodeficiency virus type 1. The New York City Perinatal HIV Transmission Collaborative Study Group.: J Infect Dis. 1995 Aug;172(2):353-8. Unique Identifier : AIDSLINE MED/95348531; Matheson PB; Abrams EJ; Thomas PA; Hernan MA; Thea DM; Lambert G; Krasinski K; Bamji M; Rogers MF; Heagarty M; Medical and Health Research Association of New York City, Inc.,; New York, USA.; New York City women (321) enrolled during 1986-1993 in an observational cohort study were analyzed retrospectively to determine the effectiveness of antenatal zidovudine in reducing perinatal transmission of human immunodeficiency virus type 1 (HIV-1) in women with various CD4+ lymphocyte counts ( 499
Correlation of clinical progression in human immunodeficiency virus-infected children with in vitro zidovudine resistance measured by a direct quantitative peripheral blood lymphocyte assay.: J Infect Dis. 1995 Aug;172(2):359-64. Unique Identifier : AIDSLINE MED/95348532; Nielsen K; Wei LS; Sim MS; Deveikis A; Keller M; Stiehm ER; Frenkel LM; Bryson YJ; Department of Pediatrics, UCLA Medical Center 90024-1752, USA.; A rapid method for determination of zidovudine resistance was developed and results were correlated with clinical outcome in human immunodeficiency virus (HIV)-infected children. The zidovudine susceptibilities of HIV-1 isolates from 34 children were determined through a direct quantitative peripheral blood lymphocyte
Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro.: J Infect Dis. 1995 Aug;172(2):380-8. Unique Identifier : AIDSLINE MED/95348535; Harmsen MC; Swart PJ; de Bethune MP; Pauwels R; De Clercq E; The TH; Meijer DK; Department of Immunology, University of Groningen, Netherlands.; Native and chemically derivatized proteins purified from serum and milk were assayed in vitro to assess their inhibiting capacity on the cytopathic effect of human immunodeficiency virus (HIV)-1 and human cytomegalovirus (HCMV) on MT4 cells and fibroblasts, respectively. Only nativ
Level of cytomegalovirus (CMV) DNA in cerebrospinal fluid of subjects with AIDS and CMV infection of the central nervous system.: J Infect Dis. 1995 Aug;172(2):527-31. Unique Identifier : AIDSLINE MED/95348554; Arribas JR; Clifford DB; Fichtenbaum CJ; Commins DL; Powderly WG; Storch GA; Edward Mallinckrodt Department of Pediatrics, Washington; University School of Medicine, St. Louis, Missouri, USA.; The objective of this study was to correlate cytomegalovirus ( CMV ) DNA levels in the cerebrospinal fluid (CSF) of subjects with AIDS with clinical and pathologic findings attributable to CMV infection of the central nervous s
Squamous epithelial proliferative lesions associated with rhesus Epstein-Barr virus in simian immunodeficiency virus-infected rhesus monkeys.: J Infect Dis. 1995 Aug;172(2):535-9. Unique Identifier : AIDSLINE MED/95348556; Baskin GB; Roberts ED; Kuebler D; Martin LN; Blauw B; Heeney J; Zurcher C; Department of Pathology, Tulane Regional Primate Research Center,; Tulane University, Covington, Louisiana 70433, USA.; Proliferative lesions were found on the squamous epithelium of the tongue, esophagus, or penis or haired skin of the lip, hand, or thorax of 8 simian immunodeficiency virus-infected rhesus monkeys that died of simian AIDS. The lesions were focal and consisted of hyperkeratosis, parakeratosis, and acanthosis in the ski
Inhibition of the offspring anti-recombinant gp120 antibody response to a human immunodeficiency virus vaccine by maternal immunization in a murine model.: J Infect Dis. 1995 Aug;172(2):539-42. Unique Identifier : AIDSLINE MED/95348557; Jelonek MT; Maskrey JL; Steimer KS; Potts BJ; Higgins KW; Keller MA; Department of Pediatrics, University of California, School of; Medicine, Harbor-UCLA Medical Center, Torrance 90509-2910, USA.; A murine model was developed for assessing the effects of passively transferred polyclonal maternal anti-gp120 antibodies on the subsequent immunization of the offspring with recombinant gp120SF2 in complete Freund s adjuvant (rgp120SF2-CFA). Adult female BALB/c mice were immunized with rgp120SF2-CFA 6 weeks before ma
Testing for antibody to human immunodeficiency virus type 1 in a population in which mycobacterial diseases are endemic.: J Infect Dis. 1995 Aug;172(2):543-6. Unique Identifier : AIDSLINE MED/95348558; Sterne JA; Turner AC; Fine PE; Parry JV; Lucas SB; Ponnighaus JM; Mkandwire PK; Nyasulu S; Warndorff DK; Communicable Disease Epidemiology Unit, London School of Hygiene; and Tropical Medicine, United Kingdom.; During a large epidemiologic study in the Karonga District of northern Malawi , serum samples from 139 patients with incident leprosy, 124 with newly diagnosed leprosy, 277 patients with incident tuberculosis, and 2296 controls were tested for antibodies to human immunodeficiency vi
Antiretroviral therapy suppresses the constitutive production of interleukin-1 associated with human immunodeficiency virus infection.: J Infect Dis. 1995 Aug;172(2):547-50. Unique Identifier : AIDSLINE MED/95348559; Sadeghi HM; Weiss L; Kazatchkine MD; Haeffner-Cavaillon N; Department of Immunology, INSERM U430, Hopital Broussais, Paris,; France.; Interleukin (IL)-1 is constitutively produced by monocytes of human immunodeficiency virus (HIV)-seropositive persons. The changes in the production of IL-1 by monocytes of 24 HIV-infected patients were investigated during the course of 8 months of antiretroviral therapy. At month 8, the amounts of biologically active
Equal IgG antibody response to pneumococcal vaccination in all stages of human immunodeficiency virus disease.: J Infect Dis. 1995 Aug;172(2):551-3. Unique Identifier : AIDSLINE MED/95348560; Vandenbruaene M; Colebunders R; Mascart-Lemone F; Haerden Y; Van Hove D; Peeters M; Goeman J; Van Royen P; Avonts D; Institute of Tropical Medicine, Antwerp, Belgium.; To evaluate the immunogenicity and safety of a 23-valent pneumococcal vaccine in human immunodeficiency virus (HIV)-seropositive patients, 80 men and 18 women received 1 dose of the vaccine (Pneumo 23; Pasteur Merieux MSD, Brussels). The total IgG antibody response against all 23 Streptococcus pneumoniae capsular anti
Mapping of linear epitopes of the regulatory proteins of human T cell lymphotropic virus (HTLV) type II: identification of an HTLV-IIb-restricted epitope.: J Infect Dis. 1995 Aug;172(2):554-7. Unique Identifier : AIDSLINE MED/95348561; Pardi D; Coligan JE; Lal RB; Retrovirus Diseases Branch, Centers for Disease Control and; Prevention, Atlanta, Georgia 30333, USA.; Epitope mapping analyses using synthetic peptides representing the RexII and TaxII proteins identified predominant seroreactivity to the carboxyl terminus of the HTLV-IIG12 TaxII protein (G12Tax 22-G12Tax24, amino acids [aa] 312-356). Moderate reactivity to only 1 RexII peptide (G12Rex9, aa 121-140) was found, while a
Impact of Streptococcus pneumoniae bacteremia and human immunodeficiency virus type 1 on oral mucosal immunity.: J Infect Dis. 1995 Aug;172(2):566-70. Unique Identifier : AIDSLINE MED/95348564; Opstad NL; Daley CL; Thurn JR; Rubins JB; Merrifield C; Hopewell PC; Janoff EN; Department of Medicine, VA Medical Center, University of; Minnesota School of Medicine, Minneapolis, MN 55417, USA.; To determine whether defects in mucosal immunity were associated with invasive disease caused by a mucosal pathogen, Streptococcus pneumoniae, levels of salivary immunoglobulins and nonspecific immune factors were compared in subjects with human immunodeficiency virus type 1 (HIV-1) infection and in HIV-1-seronegative
Efficacy and safety of desensitization to trimethoprim-sulfamethoxazole in human immunodeficiency virus-infected patients [letter]: J Infect Dis. 1995 Aug;172(2):611. Unique Identifier : AIDSLINE MED/95348580; Piketty C; Gilquin J; Kazatchkine MD
Clinical features and diagnosis of relapses in leprosy.: Indian J Lepr. 1995 Jan-Mar;67(1):45-59. Unique Identifier : AIDSLINE MED/95348589; Ramu G; 1. The definition of relapse as occurrence of new signs and symptoms of the disease during the period of surveillance or thereafter in a patient who successfully completes an adequate course of multidrug therapy accommodates the current policy of releasing patients even when there are clinical and bacteriological sign
HIV-1 infection in Juba, southern Sudan.: J Med Virol. 1995 May;46(1):18-20. Unique Identifier : AIDSLINE MED/95348663; McCarthy MC; Khalid IO; El Tigani A; U.S. Naval Medical Research Unit No. 3, Cairo, Egypt.; Thirty years of civil war in the Sudan have resulted in the isolation of the southern provinces which border Central and East Africa. Consequently, little is known about the epidemiology of HIV-1 infection in this region. To estimate the prevalence of HIV-1 infection in southern Sud
Immunogenicity and safety of an inactivated hepatitis A vaccine in anti-HIV positive and negative homosexual men.: J Med Virol. 1995 May;46(1):40-2. Unique Identifier : AIDSLINE MED/95348667; Hess G; Clemens R; Bienzle U; Schonfeld C; Schunck B; Bock HL; I. Medical Department, Klinikum der Johannes; Gutenberg-Universitat, Mainz, Germany.; The immunogenicity, reactogenicity, and safety of an inactivated hepatitis A vaccine were assessed in anti-HIV positive homosexual men. Fourteen anti-HIV positive (group 1) and 20 anti-HIV negative (group 2) men received vaccine (containing 720 ELISA units of hepatitis A antigen per dose) intramuscularly at 0, 1, and
Measurement by the polymerase chain reaction of the Epstein-Barr virus load in infectious mononucleosis and AIDS-related non-Hodgkin's lymphomas.: J Med Virol. 1995 May;46(1):66-74. Unique Identifier : AIDSLINE MED/95348673; Laroche C; Drouet EB; Brousset P; Pain C; Boibieux A; Biron F; Icart J; Denoyel GA; Niveleau A; Unite d'infectiologie, Institut Pasteur de Lyon, France.; A polymerase chain reaction (PCR) assay for the detection of Epstein-Barr virus (EBV) sequences in various clinical samples, especially peripheral blood leukocytes (PBL) and serum, was carried out and the results obtained were compared with specific EBV serology. One hundred seventy patients were enrolled in the study
A novel phorbol ester from Excoecaria agallocha.: J Nat Prod. 1995 May;58(5):769-72. Unique Identifier : AIDSLINE MED/95348715; Erickson KL; Beutler JA; Cardellina JH 2nd; McMahon JB; Newman DJ; Boyd MR; Laboratory of Drug Discovery Research and Development, National; Cancer Institute, NCI-FCRDC, Maryland 21702-1201, USA.; The novel phorbol ester 12-deoxyphorbol 13-(3E,5E-decadienoate) {1} was isolated as the anti-HIV principle of Excoecaria agallocha leaves and stems collected in northwest Australia . The structure was determined by spectral means. Compound 1 was also a potent displacer of [3H]-ph
Protective immunity to Porphyromonas gingivalis infection in a murine model.: J Periodontol. 1995 May;66(5):351-62. Unique Identifier : AIDSLINE MED/95348944; Bird PS; Gemmell E; Polak B; Paton RG; Sosroseno W; Seymour GJ; Department of Dentistry, University of Queensland, Australia.; The mouse abscess model has been used extensively to demonstrate protection after challenge with periodontopathic organisms. In the present study, an outer membrane (OM) preparation of P. gingivalis ATCC 33277 was used to immunize BALB/c mice prior to challenge with live P. gingivalis organisms. This OM preparation, p
Studies on the phenotypic and functional characterization of peripheral blood lymphocytes from patients with early-onset periodontitis.: J Periodontol. 1995 May;66(5):391-6. Unique Identifier : AIDSLINE MED/95348949; Takahashi K; Nagai A; Satoh N; Kurihara H; Murayama Y; Department of Periodontology and Endodontology, Okayama; University Dental School, Japan.; Juvenile and rapidly progressive periodontitis are grouped under the heading of patients with early-onset periodontitis (EOP). Many studies have investigated host risk factors in the etiology of EOP patients but these remain inconclusive. This study was undertaken to assess the possibility that an abnormality in the s
The winner's group: a self-help group for homeless chemically dependent persons.: J Psychosoc Nurs Ment Health Serv. 1995 Apr;33(4):14-9. Unique Identifier : AIDSLINE MED/95348988; Bennett JB; Scholler-Jaquish A; New Outlook, Glass Substance Abuse Program, Baltimore, MD, USA.; The homeless chemically addicted person presents many unique problems that cannot be addressed in standard treatment programs. Homeless clients are difficult to track and are not consistent in follow-up care. The health and mental health conditions found in this population are straining the resources of drug treatment
Complete 1H nuclear magnetic resonance assignments and structural characterization of a fusion protein of the alpha-amylase inhibitor tendamistat with the activation domain of the human immunodeficiency virus type 1 Tat protein.: J Mol Biol. 1995 Jul 28;250(5):672-88. Unique Identifier : AIDSLINE MED/95349076; Freund J; Vertesy L; Koller KP; Wolber V; Heintz D; Kalbitzer HR; Max-Planck-Institute for Medical Research, Department of; Biophysics, Heidelberg, Germany.; Complete sequence-specific assignments of the 1H-NMR spectrum of a fusion protein of the alpha-amylase inhibitor tendamistat from Streptomyces tendae and the activation domain of Tat from human immunodeficiency virus type 1 (HIV-1) was obtained by homonuclear two-dimensional NMR methods. The protein behaves as expecte
Problem-solving types among high-risk IDUs. Potential treatment implications.: J Subst Abuse Treat. 1995 Mar-Apr;12(2):103-9. Unique Identifier : AIDSLINE MED/95349079; Platt JJ; Husband SD; Steer RA; Iguchi MY; Department of Psychiatry, Medical College of Pennsylvania and; Hahnemann University, Philadelphia 19102, USA.; This research investigated whether high-risk injection drug users (IDUs) manifest distinct types, or profiles, of interpersonal cognitive problem-solving (ICPS) abilities. Four measures of ICPS, the Means-Ends Problem-Solving procedure (MEPS), Optional Thinking Test (OTT), Awareness of Consequences Test (ACT), and Cau
The alcoholics in treatment HIV risk (ATRISK) study: gender, ethnic and geographic group comparisons.: J Stud Alcohol. 1995 May;56(3):300-8. Unique Identifier : AIDSLINE MED/95349164; Scheidt DM; Windle M; Research Institute on Addictions, Buffalo, New York 14203, USA.; OBJECTIVE: This study attempted to identify alcoholic inpatients as a population at elevated risk for HIV infection in comparison with other groups. Modes of risk across gender, ethnic and geographic subgroups were explored in order to guide targeted preventive efforts in the future. METHOD: Structured interviews were
[Morbidity and mortality associated with chronic viral hepatopathy in patients infected with the human immunodeficiency virus]: Med Clin (Barc). 1995 May 6;104(17):641-4. Unique Identifier : AIDSLINE MED/95349185; Soriano V; Garcia-Samaniego J; Bravo R; Valencia E; Laguna F; de Pouplana M; Iniguez A; Munoz F; Gonzalez-Lahoz J; Servicio de Enfermedades Infecciosas, Instituto de Salud Carlos; III, Madrid.; BACKGROUND: Hepatitis B, C and D virus infection is frequent in HIV-infected individuals, particularly in drug addicts. However, chronic liver disease of viral etiology has been little studied in AIDS. METHODS: The impact of infection by hepatotropic viruses on hospital morbidity/mortality was analyzed in a group of H
[Intraoral Kaposi's sarcoma. Its epidemiology and the etiology controversies (editorial)]: Med Clin (Barc). 1995 May 6;104(17):656-7. Unique Identifier : AIDSLINE MED/95349189; Mayorga Jimenez F; Rollon Mayordomo A
[Pneumonia and bone marrow infection with Rhodococcus equi in an AIDS patient (letter; comment)]: Med Clin (Barc). 1995 May 6;104(17):678. Unique Identifier : AIDSLINE MED/95349197; Delgado Cirerol V; Rodriguez Zapata M; Espinosa Jimeno A; Sanchez Martinez L
[Guillain-Barre syndrome with anti-HIV seroconversion (letter)]: Med Clin (Barc). 1995 Jun 24;105(4):156. Unique Identifier : AIDSLINE MED/95349207; Serena J; Cortes E; de Otero J; Ribera E
[Idiopathic lactic acidosis in a patient with AIDS (letter)]: Med Clin (Barc). 1995 Jun 24;105(4):157. Unique Identifier : AIDSLINE MED/95349208; Boronat Cortes M; Estirado E; Melero M; Lopez de Letona J
[Rare forms of HIV-1 transmission (letter)]: Med Clin (Barc). 1995 Jun 24;105(4):157. Unique Identifier : AIDSLINE MED/95349209; Valles J; Gutierrez A; Gomez B
HIV test results, partner notification, and personal conduct [see comments]: Lancet. 1995 Aug 5;346(8971):326-7. Unique Identifier : AIDSLINE MED/95349225; Watters JK; Institute for Health Policy Studies, University of California,; San Francisco, USA.
Guidelines for management of HIV infection with computer-based patient's record.: Lancet. 1995 Aug 5;346(8971):341-6. Unique Identifier : AIDSLINE MED/95349230; Safran C; Rind DM; Davis RB; Ives D; Sands DZ; Currier J; Slack WV; Makadon HJ; Cotton DJ; Department of Medicine, Beth Israel Hospital, Boston, MA, USA.; Computers are steadily being incorporated in clinical practice. We conducted a nonrandomised, controlled, prospective trial of electronic messages designed to enhance adherence to clinical practice guidelines. We studied 126 physicians and nurse practitioners who used electronic medical records when caring for 349 pat
No cheers for baboon to AIDS patient xenotransplant [news] [published erratum appears in Lancet 1995 Sep 2;346(8975):650] [see comments]: Lancet. 1995 Aug 5;346(8971):369-70. Unique Identifier : AIDSLINE MED/95349237; Thompson C
Hitch in implementing Russia's HIV-prevention law [news]: Lancet. 1995 Aug 12;346(8972):432. Unique Identifier : AIDSLINE MED/95349283; Rich V
Transmission of HIV in dialysis centres [letter; comment]: Lancet. 1995 Aug 12;346(8972):451. Unique Identifier : AIDSLINE MED/95349313; Shaldon S
Diagnosis of HIV-1 group O infection by polymerase chain reaction [letter]: Lancet. 1995 Aug 12;346(8972):451-2. Unique Identifier : AIDSLINE MED/95349314; Janssens W; Fransen K; Loussert-Ajaka I; Heyndrickx L; Ivens T; Eberle J; Nkengasong J
Seizure associated with zidovudine [letter]: Lancet. 1995 Aug 12;346(8972):452. Unique Identifier : AIDSLINE MED/95349315; D'Silva M; Leibowitz D; Flaherty JP
Vesnarinone inhibits nucleoside and nucleobase transport.: Life Sci. 1995;57(6):PL75-81. Unique Identifier : AIDSLINE MED/95349329; Kumakura T; Takase K; Terada N; Gelfand EW; Department of Pediatrics, National Jewish Center for Immunology; and Respiratory Medicine, Denver, CO 80206, USA.; Vesnarinone is a novel synthetic oral inotropic agent that has been successfully used for treatment of patients with congestive heart failure. In addition to its cardiotonic activity, the drug has been proposed to have mild cytostatic and anti-HIV-1 effects. We have observed that vesnarinone profoundly inhibits radiol
Correlates of hepatitis C virus infections among injection drug users.: Medicine (Baltimore). 1995 Jul;74(4):212-20. Unique Identifier : AIDSLINE MED/95349385; Thomas DL; Vlahov D; Solomon L; Cohn S; Taylor E; Garfein R; Nelson KE; Division of Infectious Diseases, Johns Hopkins School of; Medicine, Baltimore, MD, USA.; Injection drug users are at high risk for hepatitis C virus (HCV) infection. In Baltimore, Maryland, the prevalence of anti-HCV is greater among injection drug users who are black, human immunodeficiency virus (HIV) infected, have injected longer, have injected more frequently, and have injected cocaine than among oth
Medical students in a time of HIV: education and the duty to treat.: Med Educ. 1995 Mar;29(2):128-32. Unique Identifier : AIDSLINE MED/95349430; Post SG; Botkin JR; Headrick LA; Center for Biomedical Ethics, School of Medicine, Case Western; Reserve University, Cleveland, Ohio 44106, USA.; This article concerns medical education about the ethics of professional duties and treatment of HIV-infected patients. The issue at hand is not whether medical students have a duty to treat HIV-infected patients, since it is a matter of consensus that they do. Medical schools have reasserted that risks are inherent i
Easing the growing pains [editorial]: Minn Med. 1995 Jun;78(6):5. Unique Identifier : AIDSLINE MED/95349492; Meyer CR
The doctor is in when it comes to adolescents.: Minn Med. 1995 Jun;78(6):6-7, 46-7. Unique Identifier : AIDSLINE MED/95349493; Feldman MK
Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death.: Mol Cell Biol. 1995 Aug;15(8):4064-75. Unique Identifier : AIDSLINE MED/95349572; Henderson JE; Amizuka N; Warshawsky H; Biasotto D; Lanske BM; Goltzman D; Karaplis AC; Division of Endocrinology, Sir Mortimer B. Davis-Jewish General; Hospital, Montreal, Quebec, Canada.; Parathyroid hormone-related peptide (PTHrP) is a mediator of cellular growth and differentiation as well as a cause of malignancy-induced hypercalcemia. Most of the actions of PTHrP have been attributed to its interaction with a specific cell surface receptor that binds the N-terminal domain of the protein. Here we pr
A nuclear factor (NF2d9) that binds to the male-specific P450 (Cyp 2d-9) gene in mouse liver.: Mol Cell Biol. 1995 Aug;15(8):4158-66. Unique Identifier : AIDSLINE GENBANK/U20122; Sueyoshi T; Kobayashi R; Nishio K; Aida K; Moore R; Wada T; Handa H; Negishi M; Pharmacogenetics Section, National Institute of Environmental; Health Sciences, Research Triangle Park, North Carolina 27709,; USA.; Expression of the Cyp 2d-9 (steroid 16 alpha-hydroxylase) gene in mouse liver is male specific in such Mus musculus domesticus strains as FVB/N, whereas the corresponding P450 genes in the wild mouse species Mus spretus are not sex specific in their expression. These parental differences in the gene expressions were i
Identification of positive and negative splicing regulatory elements within the terminal tat-rev exon of human immunodeficiency virus type 1.: Mol Cell Biol. 1995 Aug;15(8):4597-605. Unique Identifier : AIDSLINE MED/95349627; Staffa A; Cochrane A; Department of Microbiology and Immunology, McGill University,; Montreal, Quebec, Canada.; The requirement of human immunodeficiency virus type 1 to generate numerous proteins from a single primary transcript is met largely by the use of suboptimal splicing to generate over 30 mRNAs. To ensure that appropriate quantities of each protein are produced, there must be a signal(s) that controls the efficiency wi
Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: evidence for inhibition mediated by cellular factors [published erratum appears in Mol Cell Biol 1995 Nov;15(11):6480]: Mol Cell Biol. 1995 Aug;15(8):4606-15. Unique Identifier : AIDSLINE MED/95349628; Amendt BA; Si ZH; Stoltzfus CM; Department of Microbiology, University of Iowa, Iowa City 52242,; USA.; Human immunodeficiency virus type 1 (HIV-1) pre-mRNA splicing is regulated in order to maintain pools of unspliced and partially spliced viral RNAs as well as the appropriate levels of multiply spliced mRNAs during virus infection. We have previously described an element in tat exon 2 that negatively regulates splicin
Treatment of tuberculosis in HIV-infected patients in Zaire [letter; comment]: N Engl J Med. 1995 Aug 24;333(8):519; discussion 520. Unique Identifier : AIDSLINE MED/95349665; Pulido F; Pena JM; Rubio R
Treatment of tuberculosis in HIV-infected patients in Zaire [letter; comment]: N Engl J Med. 1995 Aug 24;333(8):519-20. Unique Identifier : AIDSLINE MED/95349666; Elliott AM; Halwiindi B; Mwinga AG
Clinical problem-solving: we blew it [letter; comment]: N Engl J Med. 1995 Aug 24;333(8):520-1. Unique Identifier : AIDSLINE MED/95349668; Gifford BD; Garrett A; Hofmann L
Nitric oxide and AIDS dementia [letter; comment]: N Engl J Med. 1995 Aug 24;333(8):521-2. Unique Identifier : AIDSLINE MED/95349670; Fuchs D; Baier-Bitterlich G; Wachter H
[Yeast infections in patients with immunologic disorders]: Ned Tijdschr Geneeskd. 1995 Jul 15;139(28):1430-6. Unique Identifier : AIDSLINE MED/95349711; van 't Wout JW; Kullberg BJ; Meis JF; Reiss P; Academisch Ziekenhuis Leiden, afd. Infectieziekten.
[Generalized histoplasmosis due to endogenous reactivation of a latent infection in an HIV-seronegative man]: Ned Tijdschr Geneeskd. 1995 Jul 15;139(28):1454-6. Unique Identifier : AIDSLINE MED/95349714; Koot RA; van Uum SH; Naber AH; Meis JF; Afd. Pathologie, Academisch Ziekenhuis, Nijmegen.; A 63-year-old, Dutch, HIV-seronegative man presented with anal pain and itch of 6 months duration, a perianal ulcer and a solitary colon ulcer. Crohn s disease was suspected; the patient was treated with corticosteroids, but later died. Autopsy revealed disseminated histoplasmosis, a fungal disease rare in the
Periodontal lesions absent in HIV-positive children [news]: N Y State Dent J. 1995 Jun-Jul;61(6):56. Unique Identifier : AIDSLINE MED/95349895
Differences in sensitivity to induction of apoptosis among rat fibroblast cells transformed by HTLV-I tax gene or cellular nuclear oncogenes.: Oncogene. 1995 Jul 6;11(1):15-20. Unique Identifier : AIDSLINE MED/95349926; Fujita M; Shiku H; Department of Oncology, Nagasaki University School of Medicine,; Japan.; The tax gene of human T lymphotropic virus type I has been implicated in the genesis of adult T cell leukemia (ATL). It has been reported that expression of tax induces neoplastic transformation in the rat fibroblast cell line Rat-1, and that co-expression with the ras gene can transform rat embryo fibroblasts. Possib
Identification of the Tax interaction region of serum response factor that mediates the aberrant induction of immediate early genes through CArG boxes by HTLV-I Tax.: Oncogene. 1995 Jul 6;11(1):7-14. Unique Identifier : AIDSLINE MED/95349938; Fujii M; Chuhjo T; Minamino T; Masaaki N; Miyamoto K; Seiki M; Department of Molecular Virology and Oncology, Kanazawa; University, Ishikawa, Japan.; Tax of human T-cell leukemia virus type I (HTLV-I) activates transcription at a CArG box of various immediate early genes such as the proto-oncogene c-fos. To do this, Tax does not directly bind to the CArG box, but instead binds to the CArG binding factor SRF. In this study, we investigated the domain of SRF required
A pilot study on the efficacy of epiroprim against developmental stages of Toxoplasma gondii and Pneumocystis carinii in animal models.: Parasitol Res. 1995;81(4):296-301. Unique Identifier : AIDSLINE MED/95350110; Mehlhorn H; Dankert W; Hartman PG; Then RL; Department of Parasitology, Ruhr University, Bochum, Germany.; The new bacteriocidal drug epiroprim (Ro-11-8958) was tested (alone or in combination with dapsone) on its efficacy against Toxoplasma gondii and Pneumocystis carinii in their hosts: laboratory mice and/or nude mice/rats, and was compared to the curative effects of the recent drugs of choice. The experiments clearly p
Stringent chemical and thermal regulation of recombinant gene expression by vaccinia virus vectors in mammalian cells.: Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6773-7. Unique Identifier : AIDSLINE MED/95350151; Ward GA; Stover CK; Moss B; Fuerst TR; MedImmune, Inc., Gaithersburg, MD 20878, USA.; We developed a stringently regulated expression system for mammalian cells that uses (i) the RNA polymerase, phi 10 promoter, and T phi transcriptional terminator of bacteriophage T7; (ii) the lac repressor, lac operator, rho-independent transcriptional terminators and the gpt gene of Escherichia coli; (iii) the RNA t
Interleukin 12 suppresses autoantibody production by reversing helper T-cell phenotype in hepatitis B e antigen transgenic mice.: Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6847-51. Unique Identifier : AIDSLINE MED/95350166; Milich DR; Wolf SF; Hughes JL; Jones JE; Department of Molecular Biology, Scripps Research Institute, La; Jolla, CA 92037, USA.; Helper T (Th) cells are classified as Th1 or Th2 cells by virtue of cytokine secretion and function as mediators of cellular or humoral immunity, respectively. Cytokines also regulate the differentiation of Th cells. For example, interleukin (IL)-12 promotes Th1 and suppresses Th2 cell development, suggesting that IL-
Inactivation of simian immunodeficiency virus by hydrostatic pressure.: Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6935-7. Unique Identifier : AIDSLINE MED/95350185; Jurkiewicz E; Villas-Boas M; Silva JL; Weber G; Hunsmann G; Clegg RM; Abteilung Virologie und Immunologie, Deutsches Primatenzentrum; GmbH, Gottigen, Germany.; The inactivation of the simian immunodeficiency viruses SIVmac251 and SIVagm by pressures of 150 and 250 MPa was determined. The extent of inactivation depended on the time that the virus was subjected to compression as well as the level of the pressure and at 150 Mpa reached 5 log10 dilution units after approximately
Psychosocial group intervention and the rate of decline of immunological parameters in asymptomatic HIV-infected homosexual men.: Psychother Psychosom. 1995;63(3-4):185-92. Unique Identifier : AIDSLINE MED/95350312; Mulder CL; Antoni MH; Emmelkamp PM; Veugelers PJ; Sandfort TG; van de Vijver FA; de Vries MJ; Helen Dowling Institute for Biopsychosocial Medicine, Rotterdam,; The Netherlands.; The aim of the study was to determine changes in the rate of decline of immunological parameters after psychosocial group intervention. Subjects were 26 asymptomatic HIV-infected homosexual men who participated in a cognitive-behavioral group therapy (CBT; n = 14), or an experiential group therapy program (ET; n = 12)
[Perceived emotional support of HIV-positive men in relation to the stage of the disease]: Psychother Psychosom Med Psychol. 1995 Jun;45(6):208-14. Unique Identifier : AIDSLINE MED/95350319; Woller W; Arendt G; Kruse J; Bostrom J; Klinisches Institut, Heinrich-Heine-Universitat, Dusseldorf.; Perceived emotional support is considered important in buffering the adverse effects of life-threatening conditions, e.g. AIDS. The aim of the present study was to investigate (1) which aspects of perceived emotional support are associated with depression, anxiety and suicidality in patients with HIV-infection, and (2
Personality, appraisal, and adaptational outcomes in HIV seropositive men and women.: Res Nurs Health. 1995 Aug;18(4):303-12. Unique Identifier : AIDSLINE MED/95350372; Anderson SE; University of Maryland, School of Nursing, Baltimore, MD; 21201-1545, USA.; A cross-sectional exploratory design was used to assess the relationships of personality, socioeconomic status, and appraisal with functional and emotional outcomes in 77 men and 50 women with HIV infection. Multiple regression analysis showed that, among men, socioeconomic status moderated the negative relationship b
Gender and knowledge about HIV, risky sexual behavior, and safer sex practices.: Res Nurs Health. 1995 Aug;18(4):313-24. Unique Identifier : AIDSLINE MED/95350373; Jadack RA; Hyde JS; Keller ML; Center for Nursing Research, Johns Hopkins University, School of; Nursing, Baltimore, MD 21205, USA.; The purpose of this study was to examine gender differences in knowledge about HIV, the reported incidence of risky sexual behavior, and comfort with safer sexual practices among young adults. The conceptual framework was social role theory, which argues for the influence of gender roles on beliefs and social behavior
Mental and physical health consequences of alcohol use in women.: Recent Dev Alcohol. 1995;12:181-97. Unique Identifier : AIDSLINE MED/95350388; Hill SY; Department of Psychiatry, University of Pittsburgh School of; Medicine, Pennsylvania 15213, USA.; Chronic consumption of alcohol in levels typically consumed by alcoholic women clearly produces adverse health consequences, including a shorter life expectancy. The health consequences of alcohol use appear to depend on the characteristics of the person consuming the alcohol (genetic vulnerability to particular disea
Early pars plana vitrectomy without buckling procedure in cytomegalovirus retinitis-induced retinal detachment.: Retina. 1995;15(2):111-6. Unique Identifier : AIDSLINE MED/95350452; Nasemann JE; Mutsch A; Wiltfang R; Klauss V; University Eye Hospital Munich, Germany.; BACKGROUND: Retinal detachments induced by cytomegalovirus ( CMV ) retinitis can often be treated successfully with a buckling procedure combined with vitrectomy and silicone oil instillation, but this technique yields varying
Stereotactic brain biopsies in AIDS patients: superior diagnostic yield with side-cutting needle than with cup forceps.: Stereotact Funct Neurosurg. 1994;63(1-4):150-3. Unique Identifier : AIDSLINE MED/95350482; Hirschfeld A; Pellegrin K; Rawanduzy A; Department of Neurosurgery, St. Vincent's Hospital, New York,; N.Y., USA.; Controversy still exists over the indicators for, and usefulness of, performing brain biopsies in AIDS patients with focal cerebral lesions. One of the sources of doubt is the relatively poor diagnostic yield in biopsying lesions in AIDS patients compared with patients who do not have AIDS. In our institution, we perf
More HIV patients may benefit from zalcitabine now [news]: RN. 1995 Jan;58(1):66. Unique Identifier : AIDSLINE MED/95350562
AIDS battle update: zidovudine okayed for pregnant women [news]: RN. 1995 Jan;58(1):67. Unique Identifier : AIDSLINE MED/95350563
Bringing AZT to poor countries [news] [see comments]: Science. 1995 Aug 4;269(5224):624-6. Unique Identifier : AIDSLINE MED/95350647; Cohen J
AIDS from vaccine? [news]: Science. 1995 Aug 4;269(5224):639. Unique Identifier : AIDSLINE MED/95350652
Behavioral risk of human immunodeficiency virus/acquired immunodeficiency syndrome in the university student community.: Sex Transm Dis. 1995 Mar-Apr;22(2):104-9. Unique Identifier : AIDSLINE MED/95350698; Latman NS; Latman AI; School of Allied Health, Texas Tech University Health Sciences; Center, Amarillo 79106, USA.; BACKGROUND AND OBJECTIVES: Theoretically, university students could be at especially high risk in a human immunodeficiency virus-type epidemic. Peak incidence of human immunodeficiency virus infection occurs in this age group. GOALS OF THIS STUDY: The purpose of this study was to examine and characterize the behavior,
The effectiveness of video-based interventions in promoting condom acquisition among STD clinic patients.: Sex Transm Dis. 1995 Mar-Apr;22(2):97-103. Unique Identifier : AIDSLINE MED/95350706; O'Donnell L; San Doval A; Duran R; O'Donnell CR; Education Development Center, Inc., Newton, MA 02160, USA.; GOAL OF THIS STUDY: This study examined the effectiveness of video-based patient education interventions on promoting condom use among men and women seeking services at a large public STD clinic in New York City. METHODS: Culturally sensitive video-based interventions designed to promote safer sex behaviors were evalu
Recurrent Staphylococcus aureus renal abscess in a child positive for the human immunodeficiency virus.: Urology. 1995 Aug;46(2):246-8. Unique Identifier : AIDSLINE MED/95350909; Brandeis JM; Baskin LS; Kogan BA; Wara D; Dorenbaum A; Department of Urology, University of California School of; Medicine, San Francisco 94143-0738, USA.; A 10-year-old girl with the human immunodeficiency virus was found to have a Staphylococcus aureus renal abscess with perinephric extension. The abscess was drained first percutaneously and then surgically, and the patient received a 6-week course of intravenous antibiotics. Three months later, the abscess recurred, n
Mixed-type auto-immune haemolytic anaemia in a patient with HIV infection.: Vox Sang. 1995;68(3):191-4. Unique Identifier : AIDSLINE MED/95350993; De Angelis V; Biasinutto C; Pradella P; Errante D; Servizio Immunotrasfusionale e Analisi Cliniche, IRCCS Centro di; Riferimento Oncologico, Aviano, Italia.; A young HIV-infected patient presented with a severe auto-immune haemolytic anaemia with both warm and cold auto-antibodies, an infrequent category of anti-erythrocyte auto-immunity. Serological findings were compatible with the presence of a low-titre, high-thermal-amplitude anti-I cold-reacting antibody and a pan-re
Heterologous HIV-2 challenge of rhesus monkeys immunized with recombinant vaccinia viruses and purified recombinant HIV-2 proteins.: Vaccine. 1995 Feb;13(2):202-8. Unique Identifier : AIDSLINE MED/95351032; Vogt G; le Grand R; Vaslin B; Boussin F; Auboyer MH; Riviere Y; Putkonen P; Sonigo P; Kieny MP; Girard M; et al; Laboratoire de Neuropathologie experimentale et Neurovirologie,; CRSSA, DSV, DPTE, CEA, Fontenay Aux Roses, France.; In an attempt to analyse the role of anti-envelope immunity in the protection of rhesus monkeys against an HIV-2 intravenous challenge, rhesus macaques were immunized twice with recombinant HIV-2 ROD vaccinia viruses (10(8) p.f.u. each) at days 0 and 30, followed by booster injections of purified HIV-2 proteins at mon
HIV-1 recombinant gp160 vaccine induced antibodies in serum and saliva. The NIAID AIDS Vaccine Clinical Trials Network.: Vaccine. 1995 Feb;13(2):209-14. Unique Identifier : AIDSLINE MED/95351033; Gorse GJ; Rogers JH; Perry JE; Newman FK; Frey SE; Patel GB; Belshe RB; Division of Infectious Diseases, Saint Louis University Health; Sciences Center, MO 63110-0250, USA.; As part of a phase I safety and immunogenicity trial of a vaccinia-expressed HIV-1 recombinant gp160 (rgp160) candidate vaccine, we measured serum and saliva antibody responses in low risk, uninfected volunteers. Six healthy adult volunteers received 50 micrograms doses of rgp160 vaccine adjuvanted in alum and deoxych
[Cytomegalovirus-induced colitis in HIV infection. Considerations on its diagnosis, treatment and complications]: Acta Med Port. 1995 Apr;8(4):247-51. Unique Identifier : AIDSLINE MED/95351140; Sousa AE; Lucas M; Palhano MJ; de Deus J; Damiao J; Victorino RM; Servico de Medicina 2, Patologia Cirurgica e Anatomia; Patologica, Hospital Universitario de Santa Maria, Lisboa.; The diagnosis of cytomegalovirus intestinal disease in patients with HIV (human immunodeficiency virus) infection frequently raises diagnostic problems in view of the absence of definite pathological, serological or virological markers of active
[Neurosyphilis and AIDS]: Acta Med Port. 1995 May;8(5):313-7. Unique Identifier : AIDSLINE MED/95351150; Quaresma MJ; Valadas E; Ferreira JJ; Servico de Doencas Infecciosas, Hospital de Santa Maria,; Lisboa.; Syphilis in HIV-infected patients reveals some particular aspects which are clinically relevant and disturbing: it is more frequent and develops more quickly to late stages, namely neurosyphilis; this progression may happen even if classic therapy in the early stages has been undertaken; the diagnosis of neurosyphilis
Talking with juvenile offenders about gay males and lesbians: implications for combating homophobia.: Adolescence. 1995 Spring;30(117):19-42. Unique Identifier : AIDSLINE MED/95351175; Van de Ven P; National Centre for HIV Social Research, School of Behavioural; Sciences, Macquarie University, NSW, Australia.; Violence against gay males and lesbians, much of it perpetrated by young people, has emerged as a significant social problem. Thirty-one juvenile offenders were asked a series of structured questions in order to elucidate the functions their attitudes toward homosexuals serve. In addition, responses were examined for
Eosinophils in lymph nodes of cows infected by bovine leukaemia virus.: Acta Vet Hung. 1995;43(1):145-51. Unique Identifier : AIDSLINE MED/95351205; Levkut M; Levkutova M; Konrad V; Polacek M; Department of Pathological Anatomy, University of Veterinary; Medicine, Kosice, Slovakia.; Prescapular lymph nodes from 109 animals positive to bovine leukaemia virus (BLV) were evaluated in this study. Lymph nodes of 81 animals (74.3%) showed an increased number of eosinophils (Eo) in a variety of pathological reactions. Eo counts in T-zonal hyperplasia (47 cases, 43.1%) and mixed hyperplasia (13 cases, 11
AIDS knowledge, attitude and behaviour patterns among university students in Ibadan, Nigeria.: Afr J Med Med Sci. 1994 Jun;23(2):119-25. Unique Identifier : AIDSLINE MED/95351219; Oladepo O; Brieger WR; Department of Preventive and Social Medicine, College of; Medicine, University of Ibadan, Nigeria.; This study investigated the knowledge, attitudes and personal behaviours of University students on AIDS. Two hundred and fifty students from the University of Ibadan randomly selected from eight faculties were surveyed. Results indicated that 58.7% of the subjects knew that AIDS is caused by a virus but 72.6% thought
Update on AIDS in men who have sex with men [news]: Am Fam Physician. 1995 Aug;52(2):667. Unique Identifier : AIDSLINE MED/95351256
A community-wide outbreak of hepatitis A: risk factors for infection among homosexual and bisexual men.: Am J Med. 1995 Aug;99(2):132-6. Unique Identifier : AIDSLINE MED/95351342; Henning KJ; Bell E; Braun J; Barker ND; Epidemiology Program Office, US Centers for Disease Control and; Prevention, Atlanta, Georgia, USA.; PURPOSE: To assess risk factors for hepatitis A infection among homosexual and bisexual men during a community-wide outbreak of hepatitis A in New York City. PATIENTS AND METHODS: Twenty-five homosexual and bisexual men, 20 to 49 years of age with hepatitis A identified from health department surveillance data (cases)
Axis II diagnoses among volunteers for HIV testing and counseling.: Am J Psychiatry. 1995 Aug;152(8):1222-4. Unique Identifier : AIDSLINE MED/95351406; Jacobsberg L; Frances A; Perry S; Cornell University Medical College, New York, NY 10021, USA.; OBJECTIVE: The authors goal was to investigate the rate of personality disorders (axis II diagnoses in DSM-III-R) among adults at risk for AIDS. METHOD: The Personality Disorder Examination was administered to 260 volunteers for HIV testing and counseling. RESULTS: Thirty-seven percent of the subjects who subsequentl
Vitamin A supplementation and morbidity in children born to HIV-infected women [editorial; comment]: Am J Public Health. 1995 Aug;85(8 Pt 1):1049-51. Unique Identifier : AIDSLINE MED/95351426; Martorell R; Ramakrishnan U
The evolving epidemiology of syphilis [editorial; comment]: Am J Public Health. 1995 Aug;85(8 Pt 1):1053-4. Unique Identifier : AIDSLINE MED/95351428; Kilmarx PH; St. Louis ME
The effects of vitamin A supplementation on the morbidity of children born to HIV-infected women [see comments]: Am J Public Health. 1995 Aug;85(8 Pt 1):1076-81. Unique Identifier : AIDSLINE MED/95351433; Coutsoudis A; Bobat RA; Coovadia HM; Kuhn L; Tsai WY; Stein ZA; Department of Paediatrics and Child Health, University of Natal,; Durban, South Africa.; OBJECTIVE. The effects of vitamin A supplementation on morbidity of children born to human immunodeficiency virus (HIV)-infected women were evaluated in a population where vitamin A deficiency is not endemic. METHODS. A randomized, placebo-controlled trial of vitamin A supplementation was carried out in 118 offspring
The classification of AIDS cases: concordance between two AIDS surveillance systems in Italy.: Am J Public Health. 1995 Aug;85(8 Pt 1):1112-4. Unique Identifier : AIDSLINE MED/95351440; Serraino D; Franceschi S; Dal Maso L; Lepri AC; Tirelli U; Rezza G; Epidemiology Unit, Aviano Cancer Centre, Italy.; This study assessed the concordance between the transmission classification of 725 acquired immunodeficiency syndrome (AIDS) cases by the Italian AIDS Registry (the national surveillance system) and the classification of the same cases by the Italian Cooperative Group on AIDS-Related Tumors. A high degree of concordan
Activity of pentostam (sodium stibogluconate) against cutaneous leishmaniasis in mice treated with neutralizing anti-interferon-gamma antibody.: Am J Trop Med Hyg. 1995 Jul;53(1):55-60. Unique Identifier : AIDSLINE MED/95351471; Nabors GS; Farrell JP; Department of Pathobiology, School of Veterinary Medicine,; University of Pennsylvania, Philadelphia, USA.; Studies with Leishmania donovani in the mouse have demonstrated that an intact T cell compartment is required for effective anti-leishmanial therapy using pentavalent antimony compounds such as Pentostam (sodium stibogluconate), suggesting that the in vivo efficacy of drug treatment is at least partially immune-based.
Primary pulmonary hypertension in association with human T-cell lymphotropic virus type I in a hemophiliac [letter]: Ann Intern Med. 1995 Sep 1;123(5):394. Unique Identifier : AIDSLINE MED/95351585; Suzuki T
AIDS Clinical Trials Group study numbers [letter; comment]: Ann Intern Med. 1995 Sep 1;123(5):395. Unique Identifier : AIDSLINE MED/95351587; von Reyn CF
Vaccine strategies: targeting helper T cell responses.: Ann N Y Acad Sci. 1995 May 31;754:126-37. Unique Identifier : AIDSLINE MED/95351594; Golding B; Scott DE; Laboratory of Plasma Derivatives, United States Food and Drug; Administration, Bethesda, Maryland 20892, USA.; Vaccine strategies need to take into account the balance of T helper subsets they induce. TH1 cells, which secrete IFN gamma and IL-2 , are associated with CMI, rather than humoral responses, and afford protection against intracellular infections including parasites. In
Liposomal vaccines: clinical status and immunological presentation for humoral and cellular immunity.: Ann N Y Acad Sci. 1995 May 31;754:143-52. Unique Identifier : AIDSLINE MED/95351596; Alving CR; Department of Membrane Biochemistry, Walter Reed Army Institute; of Research, Washington, DC 20307-5100, USA.; Liposomes have been proposed as vehicles for vaccines against parasitic and viral illnesses. Experimental vaccines against malaria, HIV, hepatitis A, and influenza virus have been shown to be safe and highly immunogenic in several human trials. Analysis of the intracellular trafficking patterns of liposomal antigen re
Immunologic adjuvants for modern vaccine formulations.: Ann N Y Acad Sci. 1995 May 31;754:153-60. Unique Identifier : AIDSLINE MED/95351597; Vogel FR; National Institute of Allergy and Infectious Diseases, Division; of AIDS, Bethesda, Maryland 20892, USA.; Optimization of the immunogenicity of many new-generation vaccine formulations, including combination vaccines, will require the use of immunologic adjuvants other than the aluminum compounds in today s licensed vaccines. The selection of adjuvants for use in vaccine formulation may be as critical as the choice of the
Designing peptide vaccines to broaden recognition and enhance potency.: Ann N Y Acad Sci. 1995 May 31;754:161-8. Unique Identifier : AIDSLINE MED/95351598; Berzofsky JA; Molecular Immunogenetics and Vaccine Research Section, National; Cancer Institute, National Institutes of Health, Bethesda,; Maryland 20892, USA.
Yeast retrotransposon particles as antigen delivery systems.: Ann N Y Acad Sci. 1995 May 31;754:202-13. Unique Identifier : AIDSLINE MED/95351602; Kingsman AJ; Burns NR; Layton GT; Adams SE; British Bio-technology Ltd., Oxford, United Kingdom.; The development of technologies to produce recombinant proteins for use in the pharmaceutical industry has made substantial advances, in particular in the area of generating antigens containing multiple copies of important immunological regions. One such antigen-carrier system is based on the ability of a protein enco
Potential alterations in immunogenicity by combining or simultaneously administering vaccine components.: Ann N Y Acad Sci. 1995 May 31;754:35-47. Unique Identifier : AIDSLINE MED/95351620; Insel RA; Department of Pediatrics, University of Rochester Medical Center,; New York 14642, USA.
Determinant flanking regions and the design of appropriate vaccines.: Ann N Y Acad Sci. 1995 May 31;754:48-56. Unique Identifier : AIDSLINE MED/95351629; Soares L; Deng H; Grewal IS; Kumar V; Miller A; Moudgil KD; Palmer M; Sercarz EE; Department of Microbiology and Molecular Genetics, University of; California, Los Angeles 90024-1489, USA.
Effect of fluconazole on pharmacokinetics of 2',3'-dideoxyinosine in persons seropositive for human immunodeficiency virus.: Antimicrob Agents Chemother. 1995 May;39(5):1050-3. Unique Identifier : AIDSLINE MED/95351740; Bruzzese VL; Gillum JG; Israel DS; Johnson GL; Kaplowitz LG; Polk RE; School of Medicine, Virginia Commonwealth University/Medical; College of Virginia, Richmond, VA 23298-0533, USA.; Fluconazole inhibits cytochrome P-450-mediated enzymatic metabolism of several drugs. Since hepatic metabolism is partially responsible for 2 ,3 -dideoxyinosine (didanosine or ddI) elimination, fluconazole therapy may lead to increased ddI concentrations in serum and subsequent concentration-dependent adverse effects.
Pharmacokinetics of dapsone in human immunodeficiency virus-infected children.: Antimicrob Agents Chemother. 1995 May;39(5):1101-6. Unique Identifier : AIDSLINE MED/95351750; Gatti G; Loy A; Casazza R; Miletich F; Cruciani M; Bassetti D; First Department of Infectious Diseases, School of Medicine,; University of Genoa, Italy.; Dapsone, administered at various doses and schedules, has been proven to be a safe and effective alternative to trimethoprim-sulfamethoxazole for prevention of Pneumocystis carinii pneumonia (PCP) in adults with human immunodeficiency virus (HIV) infection. Dapsone is also recommended by the Centers for Disease Contro
Novel mutation in the UL97 gene of a clinical cytomegalovirus strain conferring resistance to ganciclovir.: Antimicrob Agents Chemother. 1995 May;39(5):1204-5. Unique Identifier : AIDSLINE MED/95351773; Hanson MN; Preheim LC; Chou S; Talarico CL; Biron KK; Erice A; Department of Laboratory Medicine, University of Minnesota; Medical School, Minneapolis 55455-0392, USA.; Characterization of a ganciclovir-resistant cytomegalovirus strain from a patient with AIDS showed a histidine-to-glutamine change at residue 520 of UL97 (Q520 mutation). In anabolism studies, Q520 was associated with impaired phosphorylation of ganciclovir. Transfer of Q520 to a r
Early detection of catabolic state via change in 13C/12C ratios of blood proteins.: Biochem Biophys Res Commun. 1995 Jul 26;212(3):719-26. Unique Identifier : AIDSLINE MED/95352089; Hatch KA; Sacksteder KA; Treichel IW; Cook ME; Porter WP; Department of Zoology, University of Wisconsin, Madison 53706,; USA.; We find that induction of catabolic state changes the ratios of carbon 13 to carbon 12 in blood proteins. Diet can be inferred in growing chicks by feather carbon isotope ratios. This suggests an approach for early detection of catabolic state induced in patients with HIV, cancers that induce catabolism, infection ons
Synthesis and evaluation of aminoadamantane derivatives for in vitro anti-HIV and antitumor activities.: Farmaco. 1995 May;50(5):321-6. Unique Identifier : AIDSLINE MED/95352151; da Settimo A; Marini AM; Primofiore G; Da Settimo F; Dipartimento di Scienze Farmaceutiche, Universita di Pisa.; The synthesis of a series of 2-aminobenzimidazole and indole amide derivatives containing the adamantyl moiety is described. The compounds, evaluated for in vitro anti-HIV and antitumor activities, were found to be moderately active or inactive, versus drug-treated controls, used for comparison purposes.
[Association of tuberculosis and HIV infection in Brazil]: Bol Oficina Sanit Panam. 1995 Jun;118(6):542-54. Unique Identifier : AIDSLINE MED/95352212; Kritski A; Dalcolmo M; del Bianco R; del Melo FF; Pinto WP; Schechther M; Castelo A; Universidade Federal de Rio de Janeiro, Servico de Pneumologia; do Hospital Universitario Clementino Fraga Filho, Brasil.
Simultaneous occurrence of viral-associated hemophagocytic syndrome and Langerhans cell histiocytosis: a case report.: Pediatr Hematol Oncol. 1995 Mar-Apr;12(2):135-41. Unique Identifier : AIDSLINE MED/95352376; Hesseling PB; Wessels G; Egeler RM; Rossouw DJ; Department of Pediatrics and Child Health, University of; Stellenbosch, Tygerberg, Republic of South Africa.; Langerhans cell histiocytosis (LCH) is a class I histiocytosis characterized by the presence of the pathologic Langerhans cell, an unique histiocyte. In contrast to LCH, class II histiocytosis is characterized by the proliferation of mononuclear phagocytes other than Langerhans cells and includes sinus histiocytosis w
Retinal detachment and herpesvirus retinitis in patients with AIDS.: Br J Ophthalmol. 1995 Jun;79(6):575-80. Unique Identifier : AIDSLINE MED/95352584; Dowler JG; Towler HM; Mitchell SM; Cooling RJ; Lightman SL; Moorfields Eye Hospital, London.; BACKGROUND--The prolongation of survival of patients with herpesvirus retinitis and AIDS has been associated with a rise in the incidence of retinal detachment. In such cases, however, retinal reattachment may be difficult to achieve, and postoperative visual acuity may be poor despite anatomically successful surgery.
Cryptococcus presenting as cloudy choroiditis in an AIDS patient [letter]: Br J Ophthalmol. 1995 Jun;79(6):618-9. Unique Identifier : AIDSLINE MED/95352594; Verma S; Graham EM
Kinetic characterization and cross-resistance patterns of HIV-1 protease mutants selected under drug pressure.: Biochemistry. 1995 Jul 25;34(29):9282-7. Unique Identifier : AIDSLINE MED/95352609; Gulnik SV; Suvorov LI; Liu B; Yu B; Anderson B; Mitsuya H; Erickson JW; SAIC-Frederick, National Cancer Institute-Frederick Cancer; Research and Development Center, Maryland 21702-1201, USA.; Eleven different recombinant, drug-resistant HIV-1 protease (HIV PR) mutants--R8Q, V32I, M46I, V82A, V82F, V82I, I84V, V32I/I84V, M46I/V82F, M46I/I84V, and V32I/K45I/F53L/A71V/I84V/L89M--were generated on the basis of results of in vitro selection experiments using the inhibitors A-77003, A-84538, and KNI-272. Kinetic
Inhibition of cyclin-dependent kinases by p21.: Mol Biol Cell. 1995 Apr;6(4):387-400. Unique Identifier : AIDSLINE MED/95352848; Harper JW; Elledge SJ; Keyomarsi K; Dynlacht B; Tsai LH; Zhang P; Dobrowolski S; Bai C; Connell-Crowley L; Swindell E; et al; Verna & Marrs McLean Department of Biochemistry, Baylor College; of Medicine, Houston, Texas 77030, USA.; p21Cip1 is a cyclin-dependent kinase (Cdk) inhibitor that is transcriptionally activated by p53 in response to DNA damage. We have explored the interaction of p21 with the currently known Cdks. p21 effectively inhibits Cdk2, Cdk3, Cdk4, and Cdk6 kinases (Ki 0.5-15 nM) but is much less effective toward Cdc2/cyclin B (K
Viral infections of the brain.: J Neuroimaging. 1995 Jul;5 Suppl 1:S40-4. Unique Identifier : AIDSLINE MED/95352903; Masdeu JC; Van Heertum RL; Abdel-Dayem H; Department of Neurology New York Medical College, St. Vincent's; Medical Center, NY 10011, USA.; Brain infections are generally well visualized by contrast-enhanced computed tomography or magnetic resonance imaging. However, these modalities are often unrevealing in the encephalopathy produced by the human immunodeficiency virus and in the early stages of herpes simplex encephalitis. Several studies have document
[Role of retroviruses in human cancerogenesis]: Bull Cancer (Paris). 1995;82 Suppl 2:85s-92s. Unique Identifier : AIDSLINE MED/95352937; Bazarbachi A; Canivet M; Peries J; Hopital de l'Hotel-Dieu, Paris, France.; Retroviruses are viral agents which are natural and experimental inductors of leukemias and solid tumors among numerous animal species. In man, they are implicated as ethiological agents of a specific type of leukemia, adult-T cell leukemia. Thus is for retrovirus HTLV-I. Another retrovirus, HIV, implicated in AIDS is
The skeleton in the hospital closet--20 years later: malnutrition in patients with GI disease, cancer and AIDS. Proceedings a conference. Los Angeles, California, October 1-2, 1994.: Nutrition. 1995 Mar-Apr;11(2 Suppl):192-254. Unique Identifier : AIDSLINE MED/95352974
Nutritional intervention in the course of HIV disease.: Nutrition. 1995 Mar-Apr;11(2 Suppl):250-4. Unique Identifier : AIDSLINE MED/95352989; Chlebowski RT; Beall G; Lillington L; Richards EW; Abbruzzese BC; McCamish MA; Cope FO; Harbor-UCLA Medical Center, Torrance 90509, USA.
Cerebral metabolic change in patients with AIDS: report of a six-month follow-up using positron-emission tomography.: J Neuropsychiatry Clin Neurosci. 1995 Spring;7(2):180-7. Unique Identifier : AIDSLINE MED/95353044; Hinkin CH; van Gorp WG; Mandelkern MA; Gee M; Satz P; Holston S; Marcotte TD; Evans G; Paz DH; Ropchan JR; et al; UCLA School of Medicine 90024-1759, USA.; The authors examined change in cerebral metabolic function over time by using PET in HIV-infected individuals diagnosed with AIDS. Ten subjects with AIDS received [18F]2-fluoro-2-deoxy-D-glucose PET scans and completed a comprehensive neuropsychological battery. The scan and test battery were repeated after 6 months.
[Morphological characteristics of the course of HIV infection in laboratory animals]: Vestn Ross Akad Med Nauk. 1995;(6):37-41. Unique Identifier : AIDSLINE MED/95353080; Rytik PG; Il'kevich IuG; Poleshchuk NN; Miuller V; Kucherov IA; Duboiskaia GP; Podol'skaia IA; Novikova IE; Kvacheva ZB; The integrative form of infection was obtained in cotton rats intraperitoneally or retrobulbarly infected with the highly-productive strain Zmb HIV-1. Clinically, it appeared as reduced animal weight gain and high mortality rates in the disease terminal stage. The proviral DNA was detected by the polymerase chain reac
Senator's bellicosity kindles bigotry [news]: BMJ. 1995 Jul 22;311(6999):216. Unique Identifier : AIDSLINE MED/95353117; Roberts J
Linking frontline work and state-of-the-art knowledge: a community exchange system.: J Case Manag. 1995 Summer;4(2):48-53. Unique Identifier : AIDSLINE MED/95353189; Indyk D; Belville R; When challenged by complex medical and social conditions, local providers must participate in information exchanges, resource sharing, continuing education, and service coordination. A community exchange system, flexible enough to share and adapt new knowledge, and able to provide continuing multidisciplinary training
Expression and purification of active form of HIV-1 protease from E.coli.: Biochem Mol Biol Int. 1995 Apr;35(4):899-912. Unique Identifier : AIDSLINE MED/95353236; Wan M; Loh BN; Department of Biochemistry, Faculty of Medicine, National; University of Singapore, Kent Ridge Crescent.; We have subcloned an N-terminal extended protease gene of human immunodeficiency virus (HIV) type 1 that is encoded in the protease domain of the pol open reading frame into expression vector pGEX-KG. A relatively high level of expression of recombinant HIV-1 protease (PR) was achieved with isopropyl beta-D-thiogalact
Folliculostatins, gonadotropins and a model for control of growth in the grey fleshfly, Neobellieria (sarcophaga) bullata.: Insect Biochem Mol Biol. 1995 Jun;25(6):661-7. Unique Identifier : AIDSLINE MED/95353294; De Loof A; Bylemans D; Schoofs L; Janssen I; Spittaels K; Vanden Broeck J; Huybrechts R; Borovsky D; Hua YJ; Koolman J; et al; Zoological Institute of the University, Leuven, Belgium.; The sequences of two folliculostatic peptides of the fleshfly Neobellieria bullata have been determined recently. The first peptide (Neb-TMOF: H-NPTNLH-OH), originates from a 75 kDa precursor protein found in vitellogenic oocytes. The hexapeptide directly inhibits the synthesis of trypsin-like enzymes in the gut, and
Moving from autonomy to responsibility in HIV-related healthcare.: Camb Q Healthc Ethics. 1995 Winter;4(1):64-70. Unique Identifier : AIDSLINE MED/95353493; Tuohey JF
[Systemic cryptococcosis and pneumocystosis in an HIV-positive patient]: Arch Bronconeumol. 1995 Jun-Jul;31(6):296-8. Unique Identifier : AIDSLINE MED/95353553; Colomina J; Buesa J; Folgado R; Servicio de Microbiologia, Hospital Clinico Universitario,; Facultad de Medicina, Universidad de Valencia.; Cryptococcosis is one of the most common opportunistic infections in AIDS patients. Neurological symptoms are the most frequent clinical presentation of this fungal infection, and pulmonary involvement is clinically much less evident. We report the case of a patient who was treated in the emergency room for acute resp
Recent insights into the biology of the human foamy virus.: Trends Microbiol. 1995 May;3(5):173-8. Unique Identifier : AIDSLINE MED/95353585; Saib A; Peries J; de The H; CNRS UPRA0043, Hopital Saint-Louis, Paris, France.; Human foamy virus (HFV) is a complex retrovirus with structural similarities to HIV and human T cell leukemia virus. There have been considerable advances in understanding the biology of HFV in cell cultures. However, viral behavior in vivo, and even viral detection, are still poorly understood. While HFV-transgenic m
HIV integration. Ini1 for integration?: Curr Biol. 1995 Apr 1;5(4):368-70. Unique Identifier : AIDSLINE MED/95353686; Miller MD; Bushman FD; Infectious Disease Laboratory, Salk Institute, La Jolla,; California 92037, USA.; The newly discovered Ini1 cellular protein binds HIV-1 integrase and is part of a protein complex thought to alter nucleosomal structure; such alterations may influence the selection of sites for HIV-1 DNA integration.
Infection of baboons with simian/human immunodeficiency viruses.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Aug 15;9(5):429-41. Unique Identifier : AIDSLINE MED/95353763; Allan JS; Ray P; Broussard S; Whitehead E; Hubbard G; Butler T; Brasky K; Luciw P; Cheng-Mayer C; Levy JA; et al; Department of Virology and Immunology, Southwest Foundation for; Biomedical Research, San Antonio, TX 78228, USA.; Baboons were evaluated for their utility to serve as a model for testing envelope-based vaccines against human immunodeficiency virus type 1 (HIV-1). The ability of HIV-1 strains IIIB, RF, and SF2 to infect baboons was compared with that of simian/human immunodeficiency virus (SHIV) recombinant viruses comprised of ei
IL-10 synergizes with multiple cytokines in enhancing HIV production in cells of monocytic lineage.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Aug 15;9(5):442-9. Unique Identifier : AIDSLINE MED/95353764; Weissman D; Poli G; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892, USA.; Several cytokines, whose expression is increased in human immunodeficiency virus (HIV)-infected individuals, can enhance virus replication in CD4+ T lymphocytes and mononuclear phagocytes (MP). We have previously reported that interleukin (IL)-10 inhibited HIV replication in acutely infected monocyte-derived macrophag
Apoptosis-related mortality in vitro of mononuclear cells from patients with HIV infection correlates with disease severity and progression.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Aug 15;9(5):450-8. Unique Identifier : AIDSLINE MED/95353765; Pandolfi F; Pierdominici M; Oliva A; D'Offizi G; Mezzaroma I; Mollicone B; Giovannetti A; Rainaldi L; Quinti I; Aiuti F; Department of Allergy and Clinical Immunology, La Sapienza; University of Rome, Italy.; Peripheral blood mononuclear cells (PBMC) from 103 HIV-infected patients were tested for their mortality rate (MR) when incubated in vitro for 3 days in a culture medium. MR was related to apoptosis as shown by DNA analysis and morphological evaluation of ethidium bromide-stained PBMC by flow cytometry. MR was signifi
Mechanism of HIV persistence: implications for vaccines and therapy.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Aug 15;9(5):459-83. Unique Identifier : AIDSLINE MED/95353766; Bremermann HJ; Department of Molecular and Cell Biology, University of; California, Berkeley, USA.; Periodic infusion of autologous HIV-antigen presenting cells (APCs), that stimulate the cytotoxic (CTL) response, while being incapable of producing virus, should lower viral burden and boost CD4+ count in HIV-seropositive individuals. Viral burden reasserts itself after antiviral therapy ceases or is interrupted for
Increased mRNA expression of IL-6, IL-10, TNF-alpha, and perforin in blood mononuclear cells in human HIV infection.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Aug 15;9(5):484-9. Unique Identifier : AIDSLINE MED/95353767; Navikas V; Link J; Persson C; Olsson T; Hojeberg B; Ljungdahl A; Link H; Wahren B; Department of Neurology, Huddinge Hospital, Karolinska Institute,; Stockholm, Sweden.; Evidence has been presented for the involvement of various cytokines, including interleukin (IL)-6, IL-10, and tumor necrosis factor (TNF)-alpha, in the pathogenesis of human immunodeficiency virus (HIV) infection. Since measured plasma levels may poorly reflect in vivo production of cytokines, we adopted in situ hybr
Serial HIV seroprevalence surveys: interpretation, design, and role in HIV/AIDS prediction.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Aug 15;9(5):490-9. Unique Identifier : AIDSLINE MED/95353768; Ades AE; Department of Epidemiology and Biostatistics, Institute of Child; Health, London, England.; To examine the potential role of seroprevalence surveys in HIV epidemic analysis and prediction, seroprevalence was modeled in terms of age- and time-specific incidence, while taking account of the differential inclusion of infected and uninfected individuals in serosurveys. Differential inclusion had two components,
Strategies for limiting the spread of HIV in developing countries: conclusions based on studies of the transmission dynamics of the virus.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Aug 15;9(5):500-13. Unique Identifier : AIDSLINE MED/95353769; Garnett GP; Anderson RM; Department of Zoology, Oxford University, United Kingdom.; Possible interventions to reduce the spread of human immunodeficiency virus (HIV) include actions that attempt to alter sexual behaviour, such as education aimed at reducing the rate at which individuals acquire new sexual partners, and methods that reduce the probability of transmission between partners, such as the
Trends in HIV seroprevalence among persons attending sexually transmitted disease clinics in the United States, 1988-1992.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Aug 15;9(5):514-22. Unique Identifier : AIDSLINE MED/95353770; Weinstock HS; Sidhu J; Gwinn M; Karon J; Petersen LR; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, Georgia 30333, USA.; Trends in seroprevalence of the human immunodeficiency virus (HIV) were examined among patients attending sentinel clinics for sexually transmitted diseases (STDs) throughout the United States . Cross-sectional, unlinked (blinded) surveys of HIV seroprevalence were conducted annually wi
Lack of specificity of HTLV antibody enzyme immunoassays [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Aug 15;9(5):523-4. Unique Identifier : AIDSLINE MED/95353771; Jang D; Mahony JB; Sellors JW; Galli R; Gregory B; Chernesky MA
Graves' disease in HTLV-I carriers.: J Mol Med. 1995 Feb;73(2):85-8. Unique Identifier : AIDSLINE MED/95353781; Kawai H; Yokoi K; Akaike M; Kunishige M; Abe M; Tanouchi Y; Mine H; Mimura Y; Saito S; First Department of Internal Medicine, School of Medicine,; University of Tokushima, Japan.; Three carriers of human T-lymphotropic virus type I (HTLV-I) with Graves disease are reported. All three cases were complicated with uveitis, and one also showed chronic arthropathy. Anti-HLTV-I antibody was found in the serum by the particle agglutination method and western blotting, and HTLV-I proviral DNA was dete
[Herpesvirus infection: from the primary oral lesion to recurrent herpes]: J Can Dent Assoc. 1995 Jul;61(7):623-4, 627-30. Unique Identifier : AIDSLINE MED/95354072; Lacroix I; Mascres C; Hopital Ste Justine.; This paper presents an overview of the clinical conditions associated with a herpetic lesion at the time of the primary infection, as a true primary infection or a first herpetic accident, or during recurrences. The virus responsible, its anatomy and its functioning are detailed. The etiology and transmission of herpe
HIV-1 associated dementia: clinical features and pathogenesis.: Can J Neurol Sci. 1995 May;22(2):92-100. Unique Identifier : AIDSLINE MED/95354103; Power C; Johnson RT; Department of Neurology, Johns Hopkins University, Baltimore,; USA.; HIV-1 infection is characterized by multiple neurological syndromes occurring at all stages of infection. HIV-1-associated dementia , however, is the most devastating CNS consequence of AIDS because of its poor prognosis and functional impairment. A clinical triad of progressive cog
The induction of cytotoxic T cells and tumor regression by soluble antigen formulation.: Cancer Res. 1995 Aug 15;55(16):3486-9. Unique Identifier : AIDSLINE MED/95354133; Hariharan K; Braslawsky G; Black A; Raychaudhuri S; Hanna N; IDEC Pharmaceuticals Corporation, San Diego, California 92121,; USA.; CTLs specific for tumor antigens play a major role in the immunity against cancer. We have shown that class I-restricted CTLs can be induced by injecting soluble antigens mixed in an antigen formulation (AF) that consists of squalane, Tween 80, and Pluronic L121 (S. Raychaudhuri et al., Proc. Natl. Acad. Sci. USA, 89:
Production of interleukin 8 in adult T-cell leukemia cells: possible transactivation of the interleukin 8 gene by human T-cell leukemia virus type I tax.: Cancer Res. 1995 Aug 15;55(16):3592-7. Unique Identifier : AIDSLINE MED/95354152; Mori N; Murakami S; Oda S; Prager D; Eto S; First Department of Internal Medicine, University of Occupational; and Environmental Health, School of Medicine, Kitakyushu, Japan.; Interleukin 8 (IL-8) mRNA was detected in peripheral leukemic cells obtained from adult T-cell leukemia patients, as well as in cultured human T-cell leukemia virus type I (HTLV-I)-infected T-cell lines (HUT-102, MT-1, SALT-3, and SKT-1B). With the use of ELISA, IL-8 protein was also detected in the culture medium of
Synthesis of (3'R)-3'-deoxy-3'-C-nitromethylthymidine.: Carbohydr Res. 1995 Apr 18;270(1):77-83. Unique Identifier : AIDSLINE MED/95354178; Takahashi Y; Honda Y; Tsuchiya T; Institute of Bioorganic Chemistry, Kawasaki, Japan.
A rat monoclonal anti-(human CD2) and L-leucine methyl ester impacts on human/SCID mouse graft and B lymphoproliferative syndrome.: Cancer Immunol Immunother. 1995 Jun;40(6):383-9. Unique Identifier : AIDSLINE MED/95354183; Bombil F; Kints JP; Havaux X; Scheiff JM; Bazin H; Latinne D; Experimental Immunology Unit, University of Louvain, Brussels,; Belgium.; The transfer of human peripheral blood mononuclear cells (hu-PBMC) from adult Epstein-Barr-virus(EBV)-seropositive donors in SCID (severe combined immunodeficiency) mice frequently leads to the development of a human B lymphoproliferative syndrome (hu-BLPS). Therefore, as 90% of adult potential donors are EBV-seroposi
Paediatric treatment costs and the HIV epidemic.: Cent Afr J Med. 1995 May;41(5):139-44. Unique Identifier : AIDSLINE MED/95354187; Nelson E; Weikert M; Phillips JA; Department of Paediatrics, Kamuzu Central Hospital, Lilongwe.; As the AIDS epidemic puts additional strains on the already overburdened health care systems in sub-Saharan Africa, it becomes more important to estimate the cost of the epidemic in terms of health personnel and drug treatments. A retrospective review of 250 randomly selected paediatric admissions to a referral hospit
The enigma of HIV infection.: Cell. 1995 Jul 28;82(2):175-6. Unique Identifier : AIDSLINE MED/95354197; Baltimore D; Whitehead Institute, Massachusetts Institute of Technology 02139,; USA.
Can the immune response control HIV infection?: Cell. 1995 Jul 28;82(2):177-82. Unique Identifier : AIDSLINE MED/95354198; Paul WE; Office of AIDS Research, National Institutes of Health, Bethesda,; Maryland 20892, USA.
Viral latency in HIV disease.: Cell. 1995 Jul 28;82(2):183-8. Unique Identifier : AIDSLINE MED/95354199; McCune JM; Gladstone Institute of Virology and Immunology, San Francisco; General Hospital, University of California 94141-9100, USA.
HIV accessory proteins: leading roles for the supporting cast.: Cell. 1995 Jul 28;82(2):189-92. Unique Identifier : AIDSLINE MED/95354200; Trono D; Infectious Disease Laboratory, Salk Institute for Biological; Studies, La Jolla, California 92037, USA.
Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration.: Cell. 1995 Jul 28;82(2):209-20. Unique Identifier : AIDSLINE MED/95354202; Rice P; Mizuuchi K; Laboratory of Molecular Biology, National Institute of Diabetes; and Digestive and Kidney Diseases, National Institutes of Health,; Bethesda, Maryland 20892-0540, USA.; The crystal structure of the core domain of bacteriophage Mu transposase, MuA, has been determined at 2.4 A resolution. The first of two subdomains contains the active site and, despite very limited sequence homology, exhibits a striking similarity to the core domain of HIV-1 integrase, which carries out a similar set
A protease assay using time-resolved lanthanide luminescence from an engineered calcium binding protein substrate.: Clin Biochem. 1995 Apr;28(2):131-5. Unique Identifier : AIDSLINE MED/95354270; Clark ID; MacManus JP; Szabo AG; Institute for Biological Sciences, National Research Council,; Ottawa, Ontario, Canada.; OBJECTIVES: The objective of this work was to demonstrate the utility of luminescence from lanthanides bound to a mutant of the Ca2+ binding protein, oncomodulin, to monitor protease activity. DESIGN AND METHODS: A mutant of oncomodulin with a cysteine residue at position 57 located in the CD binding loop was conjugat
Thallium and gallium scintigraphy in pulmonary Kaposi's sarcoma in an HIV-positive patient [letter; comment]: Clin Nucl Med. 1995 May;20(5):473. Unique Identifier : AIDSLINE MED/95354367; Abdel-Dayem H
Pharmacokinetics of an anti-human immunodeficiency virus antisense oligodeoxynucleotide phosphorothioate (GEM 91) in HIV-infected subjects.: Clin Pharmacol Ther. 1995 Jul;58(1):44-53. Unique Identifier : AIDSLINE MED/95354388; Zhang R; Yan J; Shahinian H; Amin G; Lu Z; Liu T; Saag MS; Jiang Z; Temsamani J; Martin RR; et al; Department of Pharmacology and Toxicology, University of Alabama; at Birmingham 35294-0019, USA.; Human pharmacokinetics of an antisense oligodeoxynucleotide phosphorothioate (GEM 91) developed as an anti-human immunodeficiency virus (HIV) agent was carried out in this study. 35S-Labeled GEM 91 was administered to six HIV-infected individuals by means of 2-hour intravenous infusions at a dose of 0.1 mg/kg. Plasma
Acetylcholinesterase inhibition by zifrosilone: pharmacokinetics and pharmacodynamics.: Clin Pharmacol Ther. 1995 Jul;58(1):54-61. Unique Identifier : AIDSLINE MED/95354389; Cutler NR; Seifert RD; Schleman MM; Sramek JJ; Szylleyko OJ; Howard DR; Barchowsky A; Wardle TS; Brass EP; California Clinical Trials, Beverly Hills 90211, USA.; OBJECTIVE: To determine the pharmacokinetics, pharmacodynamics and safety of the acetylcholinesterase inhibitor zifrosilone in healthy male volunteers. METHODS: Pharmacokinetics, pharmacodynamics, and tolerance of zifrosilone were studied in a double-blind, sequential, single-escalating-dose, randomized panel design.
Pneumonia with pleural effusion due to Legionella pneumophila serogroup Lansing 3.: Diagn Microbiol Infect Dis. 1995 Feb;21(2):101-3. Unique Identifier : AIDSLINE MED/95354395; Martin WT; Boyle CA; Bernard K; Williams KE; Conly JM; Division of Clinical Microbiology, Royal University Hospital,; Saskatoon, Saskatchewan, Canada.; We describe a case of pneumonia with pleural effusion due to Legionella pneumophila serogroup Lansing 3 in a human immunodeficiency virus-infected person. The 55-year-old man had been treated with immunosuppressive agents for hypersensitivity pneumonitis.
Acrosin inhibitor, 4'-acetamidophenyl 4-guanidinobenzoate, an experimental vaginal contraceptive with anti-HIV activity.: Contraception. 1995 May;51(5):319-22. Unique Identifier : AIDSLINE MED/95354415; Bourinbaiar AS; Lee-Huang S; Department of Biochemistry, New York University Medical Center,; NY 10016, USA.; Serine proteases are involved in a wide variety of seemingly unrelated physiological functions including capacitation of the spermatozoa and potentiation of human immunodeficiency virus (HIV) infection. The experimental vaginal contraceptives derived from 4-guanidinobenzoic acid act through inhibition of acrosin--a se
Suppression of hepatitis C virus (HCV) replication by hepatitis D virus (HDV) in HIV-infected hemophiliacs with chronic hepatitis B and C.: Dig Dis Sci. 1995 Jul;40(7):1583-8. Unique Identifier : AIDSLINE MED/95354499; Eyster ME; Sanders JC; Battegay M; Di Bisceglie AM; Department of Medicine, Pennsylvania State University School of; Medicine, Hershey, USA.; Most hemophiliacs who are coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) have high serum levels of HCV RNA. To study the impact of multiple hepatitis virus infections, we evaluated all eight chronic carriers of hepatitis B surface antigen (HBsAg) from a previously studied cohort of 99 h
Comparative metabolism of 3'-azido-3'-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans.: Drug Metab Dispos. 1995 Mar;23(3):308-13. Unique Identifier : AIDSLINE MED/95354505; Nicolas F; De Sousa G; Thomas P; Placidi M; Lorenzon G; Rahmani R; INSERM, Centre de Recherche Agronomique, Antibes, France.; 3 -Azido-3 -deoxythymidine ( AZT ), the main antiretroviral drug used against Human Immunodeficiency Virus, was approved by the Food and Drug Administration in 1987 with only little knowledge concerning its metabolism. The aim of our study was to evalua
[Is HIV transmissible through insect stings?]: Dtsch Med Wochenschr. 1995 Jul 28;120(30):1060. Unique Identifier : AIDSLINE MED/95354532; Weber B; Doerr HW; Institut fur Medizinische Virologie, Universitat,; Frankfurt/Main.
Idiopathic hypereosinophilic syndrome with a radiologic pattern of central pontine myelinolysis [letter]: Eur Neurol. 1995;35(3):174-5. Unique Identifier : AIDSLINE MED/95354719; Menage P; de Toffol B; Saudeau D; Watier H; Bardos P; Autret A
The post-transcriptional regulator Rex of the human T-cell leukemia virus type I is present as nucleolar speckles in infected cells.: Exp Cell Res. 1995 Jul;219(1):122-9. Unique Identifier : AIDSLINE MED/95354749; Nosaka T; Miyazaki Y; Takamatsu T; Sano K; Nakai M; Fujita S; Martin TE; Hatanaka M; Institute for Virus Research, Kyoto University, Japan.; The rex-encoded protein (Rex) of human T-cell leukemia virus type I (HTLV-I) is responsible for the cytoplasmic accumulation of incompletely spliced mRNAs that encode the virion structural proteins. Rex is known to be located predominantly in the cell nucleoli in transient transfections or in the isolated nuclei of HT
The cytotoxicity of human immunodeficiency virus type 1 Rev: implications for its interaction with the nucleolar protein B23.: Exp Cell Res. 1995 Jul;219(1):93-101. Unique Identifier : AIDSLINE MED/95354782; Miyazaki Y; Takamatsu T; Nosaka T; Fujita S; Martin TE; Hatanaka M; Institute for Virus Research, Kyoto University, Japan.; Human immunodeficiency virus type 1 (HIV-1) encodes several regulatory proteins, including two essential trans-activators for viral replication, Rev and Tat. Both Rev and Tat have a nucleolar targeting signal and are actually located predominantly in the nucleoli. Within the nucleoli, Rev is localized to the combined
Study of the role of vitamin B12 and folinic acid supplementation in preventing hematologic toxicity of zidovudine.: Eur J Haematol. 1995 Aug;55(2):97-102. Unique Identifier : AIDSLINE MED/95354826; Falguera M; Perez-Mur J; Puig T; Cao G; Service of Internal Medicine, Arnau de Vilanova Hospital, Lleida,; Spain.; A prospective, randomized study was conducted to evaluate the role of vitamin B12 and folinic acid supplementation in preventing zidovudine (ZDV)-induced bone marrow suppression. Seventy-five human immunodeficiency virus (HIV)-infected patients with CD4+ cell counts
Resistant P45051A1 activity in azole antifungal tolerant Cryptococcus neoformans from AIDS patients.: FEBS Lett. 1995 Jul 17;368(2):326-30. Unique Identifier : AIDSLINE MED/95354863; Lamb DC; Corran A; Baldwin BC; Kwon-Chung J; Kelly SL; Krebs Institute for Biomolecular Research, Department of; Molecular Biology and Biotechnology, Sheffield University, UK.; Azole antifungal compounds are important in the treatment of Cryptococcosis, a major cause of mortality in AIDS patients. The target of the azole drugs is P450 mediated sterol 14 alpha-demethylase. We have investigated the P450 system of Cryptococcus neoformans with respect to azole tolerance observed in clinical isol
Pancreatic disorders in pediatric acquired immune deficiency syndrome.: Hum Pathol. 1995 Jul;26(7):765-70. Unique Identifier : AIDSLINE MED/95355119; Kahn E; Anderson VM; Greco MA; Magid M; North Shore University Hospital-Cornell University Medical; College, Manhasset, NY 11030, USA.; Acute pancreatitis, reported in 17% of pediatric patients with acquired immune deficiency syndrome (AIDS), is said to have a poor prognosis. We describe the pancreatic changes observed at autopsy from 71 children with human immunodeficiency virus (HIV) infection and document their nature, extent, and clinical relevanc
Conformational changes induced in the endoplasmic reticulum luminal domain of calnexin by Mg-ATP and Ca2+.: J Biol Chem. 1995 Jul 28;270(30):18051-9. Unique Identifier : AIDSLINE GENBANK/X53616; Ou WJ; Bergeron JJ; Li Y; Kang CY; Thomas DY; Biotechnology Research Institute, National Research Council of; Canada, Montreal, Quebec.; The type I membrane protein calnexin functions as a molecular chaperone for secretory glycoproteins in the endoplasmic reticulum with ATP and Ca2+ as two of the cofactors involved in substrate binding. Protease protection experiments with intact canine rough microsomes showed that amino acid residues 1-462 of calnexin
False negative results in enzyme linked immunosorbent assays using synthetic HIV antigens.: J Clin Pathol. 1995 May;48(5):490-3. Unique Identifier : AIDSLINE MED/95355618; McAlpine L; Parry JV; Shanson D; Mortimer PP; Hepatitis and Retrovirus Laboratory, PHLS Virus Reference; Division, Central Public Health Laboratory, London.; The sensitivity of 12 commonly used anti-HIV-1/HIV-2 enzyme immunoassays was evaluated. The assays, each of which utilises at least one synthetic HIV antigen, were tested against a panel of 1092 specimens previously designated anti-HIV positive. In a total of 13 104 tests there were eight false negative results attrib
Assessing HIV-related attitudes and orientations of male and female general dentists.: J Am Dent Assoc. 1995 Jul;126(7):862-71. Unique Identifier : AIDSLINE MED/95355686; Kunzel C; Sadowsky D; Division of Community Health, Columbia University School of; Dental and Oral Surgery, New York 10032, USA.; This article examines differences between male and female general practitioners in private practice in New York City with regard to their attitudes and orientations toward treating HIV-infected patients. The survey asked about willingness to treat such patients and perceptions that might influence that willingness, pa
Prevalence of hepatitis B virus (HBV) infection in Singapore men with sexually transmitted diseases and HIV infection: role of sexual transmission in a city state with intermediate HBV endemicity.: J Epidemiol Community Health. 1995 Jun;49(3):309-13. Unique Identifier : AIDSLINE MED/95355801; Heng BH; Goh KT; Chan R; Chew SK; Doraisingham S; Quek GH; Quarantine and Epidemiology Department, Ministry of the; Environment, Singapore.; STUDY OBJECTIVES--To describe the prevalence of hepatitis B virus (HBV) infection in patients with sexually transmitted diseases (STD) and human immunodeficiency virus (HIV) infection, and to determine the role of sexual transmission of HBV infection in Singapore . DESIGN--A cros
Formation of simian immunodeficiency virus long terminal repeat circles in resting T cells requires both T cell receptor- and IL-2-dependent activation.: J Exp Med. 1995 Aug 1;182(2):617-21. Unique Identifier : AIDSLINE MED/95355864; Polacino PS; Liang HA; Clark EA; Washington Regional Primate Research Center, University of; Washington, Seattle 98195, USA.; Although immunodeficiency viruses can enter resting CD4+ T lymphocytes, activation of T cells is required for complete viral cDNA synthesis and transport of double-stranded viral DNA to the nucleus. Cross-linking T cell receptors (TCRs) on resting CD4+ T cells induces reverse transcription of full-length simian immuno
Cloning and characterization of a new isoform of the interleukin 1 receptor antagonist.: J Exp Med. 1995 Aug 1;182(2):623-8. Unique Identifier : AIDSLINE GENBANK/X84348; Muzio M; Polentarutti N; Sironi M; Poli G; De Gioia L; Introna M; Mantovani A; Colotta F; Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.; By reverse transcriptase polymerase chain reaction on messenger RNA from human polymorphonuclear cells, we have isolated a sequence identical to the cDNA coding for intracellular interleukin 1 receptor antagonist (icIL-1ra), but containing an additional in-frame 63-bp sequence located three codons downstream of the tr
AZT reduces HIV transmission from infected moms to their newborns [news]: J Okla State Med Assoc. 1995 Jun;88(6):270-1. Unique Identifier : AIDSLINE MED/95355960
T-helper-2 lymphocytes as a peripheral target of melatonin.: J Pineal Res. 1995 Mar;18(2):84-9. Unique Identifier : AIDSLINE MED/95356044; Maestroni GJ; Centre for Experimental Pathology, Istituto Cantonale di; Patologia, Locamo, Switzerland.; In the past several years we demonstrated that the pineal neurohormone melatonin has immunoenhancing properties and can counteract the immunodepression that may follow acute stress, drug treatment, and viral diseases or aging. Several laboratories have subsequently confirmed and extended our findings. It soon appeared
Cameo of caring: George.: J Christ Nurs. 1995 SUM;12(3):9. Unique Identifier : AIDSLINE MED/95356073; Grem CA
Tuberculosis and AIDS.: J Med Microbiol. 1995 Aug;43(2):85-91. Unique Identifier : AIDSLINE MED/95356214; Drobniewski FA; Pozniak AL; Uttley AH; Regional Tuberculosis Centre, Dulwich Public Health Laboratory,; King's College School of Medicine and Dentistry, London.; Since the mid-1980s, the rate of decline in reported cases of tuberculosis (TB) has reached a plateau or reversed because of a combination of poverty and increased homelessness, immigration and displacement, poorly managed and supplied TB control programmes and, particularly in the developing world, the emergence of h
Effect of human T-lymphotropic virus type I infection on non-Hodgkin's lymphoma incidence [see comments]: J Natl Cancer Inst. 1995 Jul 5;87(13):1009-14. Unique Identifier : AIDSLINE MED/95356226; Cleghorn FR; Manns A; Falk R; Hartge P; Hanchard B; Jack N; Williams E; Jaffe E; White F; Bartholomew C; et al; Division of Cancer Etiology, National Cancer Institute, National; Institutes of Health, Bethesda, MD, USA.; BACKGROUND: We previously reported from a case-control analysis that T-cell non-Hodgkin s lymphoma (NHL) was strongly associated with human T-lymphotropic virus type I (HTLV-I) infection in Jamaica and
Viral-associated neoplasms in humans: additional clues [editorial; comment]: J Natl Cancer Inst. 1995 Jul 5;87(13):947-9. Unique Identifier : AIDSLINE MED/95356234; Levine AM
Isolation and characterization of an immortal neoplastic cell line (KS Y-1) from AIDS-associated Kaposi's sarcoma [see comments]: J Natl Cancer Inst. 1995 Jul 5;87(13):974-81. Unique Identifier : AIDSLINE MED/95356240; Lunardi-Iskandar Y; Gill P; Lam VH; Zeman RA; Michaels F; Mann DL; Reitz MS Jr; Kaplan M; Berneman ZN; Carter D; et al; BACKGROUND: Acquired immunodeficiency syndrome (AIDS) is associated with the occurrence of tumors such as Kaposi s sarcoma (KS) and B-cell lymphoma. However, no evidence exists yet that human immunodeficiency virus type 1, the causative agent of AIDS, is directly responsible for cell transformation. It is also not cle
Cancer drug may join the AIDS arsenal [news]: JAMA. 1995 Aug 16;274(7):523. Unique Identifier : AIDSLINE MED/95356328; Voelker R
Natural history of HIV-1 cell-free viremia [see comments]: JAMA. 1995 Aug 16;274(7):554-8. Unique Identifier : AIDSLINE MED/95356346; Henrard DR; Phillips JF; Muenz LR; Blattner WA; Wiesner D; Eyster ME; Goedert JJ; Department of Medical Research, Abbott Laboratories, North; Chicago, Ill., USA.; OBJECTIVE--To characterize the natural history of viremia with human immunodeficiency virus type 1 (HIV-1) and its association with disease progression from infection to acquired immunodeficiency syndrome (AIDS). DESIGN--Prospective cohort study. Annual specimens were tested for quantitative virion-associated HIV-1 RN
[The successful attempt to overcome anxiety and insecurity towards AIDS patients. How I turned into a reliable companion]: Krankenpfl Soins Infirm. 1995 Jul;88(7):6-13. Unique Identifier : AIDSLINE MED/95356472; Holzer M
Serologic and molecular evidence for a possible pathogenetic role of viral infection in CD3-negative natural killer-type lymphoproliferative disease of granular lymphocytes.: Leukemia. 1995 Jul;9(7):1207-11. Unique Identifier : AIDSLINE MED/95356572; Zambello R; Loughran TP Jr; Trentin L; Pontisso P; Battistella L; Raimondi R; Facco M; Sancetta R; Agostini C; Pizzolo G; et al; Department of Clinical Medicine, Padua University School of; Medicine, Italy.; We studied a series of 18 patients with CD3- lymphoproliferative disease of granular lymphocytes (LDGL) for evidence of chronic viral infection, including Epstein-Barr (EBV), hepatitis B (HBV), hepatitis C (HCV), human T lymphotropic virus (HTLV), and human immunodeficiency virus (HIV). Although all patients tested ha
Skin cancers associated with acquired immunodeficiency syndrome.: Mayo Clin Proc. 1995 Aug;70(8):766-72. Unique Identifier : AIDSLINE MED/95356596; Wang CY; Brodland DG; Su WP; Department of Dermatology, Mayo Clinic Rochester, Minnesota; 55905, USA.; OBJECTIVE: To describe the types of skin cancer associated with the acquired immunodeficiency syndrome (AIDS). DESIGN: A literature review of AIDS-related mucocutaneous neoplasms, including basal cell carcinoma, squamous cell carcinoma, bowenoid papulosis and Bowen s disease, squamous cell carcinoma, cloacogenic carci
[A descriptive clinical study of a type of arthritis in beekeepers of the Badajoz area of La Siberia Extremena]: Med Clin (Barc). 1995 Jul 1;105(5):164-7. Unique Identifier : AIDSLINE MED/95356608; Pena J; Salazar JM; Ortega R; Alvarez JL; Campillo JE; Torres MD; Departamento de Fisiologia, Facultad de Medicina, Hospital; Infanta Cristina, Universidad de Extremadura, Badajoz.; BACKGROUND: The appearance of episodes of arthritis has been detected in beekeepers in the Siberia Extremadura ( Spain ) related to working with the hives. This present work describes the clinical features of such arthritic syndrome. METHODS: Sixty cases were selected at random from a
[HIV without AIDS but no AIDS without HIV (editorial)]: Med Clin (Barc). 1995 Jul 1;105(5):172-3. Unique Identifier : AIDSLINE MED/95356610; Soriano V; Gonzalez-Lahoz J
Preventing AIDS: have we lost our way?: Lancet. 1995 Jul 29;346(8970):262-3. Unique Identifier : AIDSLINE MED/95356623; Lifson AR; Division of Epidemiology, School of Public Health, University of; Minnesota, Minneapolis, USA.
Practising obstetrics and gynaecology in areas with a high prevalence of HIV infection [see comments]: Lancet. 1995 Jul 29;346(8970):293-6. Unique Identifier : AIDSLINE MED/95356634; Verkuyl DA; What is it like to practise obstetrics and gynaecology in a country with a high prevalence of HIV infection? My experience relates especially to Zimbabwe , but the same factors apply equally well to Zambia , Zai
Evidence for HIV-1 group O infection in Nigeria [letter; comment]: Lancet. 1995 Jul 29;346(8970):308. Unique Identifier : AIDSLINE MED/95356643; Kabeya CM; Esu-Williams E; Eni E; Peeters M; Saman E; Delaporte E
Surveillance of heterosexually acquired HIV infection and AIDS [letter] [see comments]: Lancet. 1995 Jul 29;346(8970):308-9. Unique Identifier : AIDSLINE MED/95356644; Morlat P; Helmer C; Chene G; Bernard N; Monlun E; Beylot J; Dabis F
Chemosensory function and diet in HIV-infected patients.: Laryngoscope. 1995 Aug;105(8 Pt 1):862-6. Unique Identifier : AIDSLINE MED/95356686; Mattes RD; Wysocki CJ; Graziani A; MacGregor RR; Monell Chemical Senses Center, Philadelphia, PA 19104-3308, USA.; Alterations of chemosensory function have been noted in human immunodeficiency virus (HIV)-infected patients, but their frequency, severity, and relationship to diet have not been adequately assessed. Odor and taste identification tests and a taste-intensity scaling task were administered to 25 men who were HIV-infect
2',3'-Dideoxycytidine induced drug resistance in human cells.: Life Sci. 1995;57(9):881-7. Unique Identifier : AIDSLINE MED/95356702; Magnani M; Gazzanelli G; Brandi G; Casabianca A; Fraternale A; Chiarantini L; Rossi L; Istituto di Chimica Biologica G. Fornaini, Universita degli; Studi, Urbino, Italy.; 2 ,3 -Dideoxycytidine ( ddC ) is a nucleoside analogue that inhibits HIV-1 replication in vitro and is currently used in AIDS therapy. This compound exerts a delayed cytotoxicity due to inhibition of mitochondrial DNA (mDNA) synthesis. We have found tha
Update: HIV-2 infection among blood and plasma donors--United States, June 1992-June 1995.: MMWR Morb Mortal Wkly Rep. 1995 Aug 18;44(32):603-6. Unique Identifier : AIDSLINE MED/95356726; Human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) both cause acquired immunodeficiency syndrome (AIDS). Following the licensure of combination HIV-1/HIV-2 screening enzyme immunoassays (EIA), the Food and Drug Administration ( FDA ) recommended that beginning in June 1992 a
Detection of HTLV-I provirus by in situ polymerase chain reaction in mononuclear inflammatory cells in skeletal muscle of viral carriers with polymyositis.: Muscle Nerve. 1995 Aug;18(8):854-8. Unique Identifier : AIDSLINE MED/95356758; Higuchi I; Hashimoto K; Kashio N; Izumo S; Inose M; Izumi K; Ohkubo R; Nakagawa M; Arimura K; Osame M; Third Department of Internal Medicine, Kagoshima University,; Japan.; We tested for HTLV-I proviral DNA in skeletal muscle from patients with polymyositis infected with HTLV-I using the in situ polymerase chain reaction. We found the HTLV-I provirus in some of the CD4-positive cells in HTLV-I-positive polymyositis cases but not in HTLV-I-negative polymyositis ones. We could not detect H
Transient myasthenia gravis during HIV infection.: Muscle Nerve. 1995 Aug;18(8):914-6. Unique Identifier : AIDSLINE MED/95356768; Authier FJ; De Grissac N; Degos JD; Gherardi RK; Service de Neurologie, Hopital Henri Mondor, Creteil, France.
HTLV-1 associated pandysautonomia with adrenal dysfunction [letter]: Muscle Nerve. 1995 Aug;18(8):928-9. Unique Identifier : AIDSLINE MED/95356776; Ando Y; Ando E; Vchino M; Ando M
[HIV-associated mycoses]: Mycoses. 1995;38 Suppl 1:40-4. Unique Identifier : AIDSLINE MED/95356782; Listemann H; Meigel W; Abteilung Dermatologie, Allgemeines Krankenhaus St. Georg,; Hamburg, BR Deutschland.; Candidosis, cryptococcosis, and histoplasmosis often occur as HIV-associated mycoses. However, aspergillosis can be observed quite recently. The morphology of the pathogen of HIV-associated mycoses in vivo and in vitro is demonstrated and discussed.
HIV scandal hits Bombay blood centre [news]: Nature. 1995 Jul 27;376(6538):285. Unique Identifier : AIDSLINE MED/95356802; Jayaraman KS
Essential role for ZAP-70 in both positive and negative selection of thymocytes.: Nature. 1995 Aug 3;376(6539):435-8. Unique Identifier : AIDSLINE MED/95356836; Negishi I; Motoyama N; Nakayama K; Nakayama K; Senju S; Hatakeyama S; Zhang Q; Chan AC; Loh DY; Howard Hughes Medical Institute, Department of Medicine,; Washington University School of Medicine, St Louis, Missouri; 63110, USA.; During thymic development, T cells that can recognize foreign antigen in association with self major histocompatibility complex (MHC) are selected for survival (positive selection) and autoreactive T cells are eliminated (negative selection). Both of these selective events are mediated by interaction between the T-cel
Acquiring HIV on the job.: Nursing. 1995 Jul;25(7):30. Unique Identifier : AIDSLINE MED/95356972
A phase I/II evaluation of stavudine (d4T) in children with human immunodeficiency virus infection.: Pediatrics. 1995 Aug;96(2 Pt 1):247-52. Unique Identifier : AIDSLINE MED/95357106; Kline MW; Dunkle LM; Church JA; Goldsmith JC; Harris AT; Federici ME; Schultze ME; Woods L; Loewen DF; Kaul S; et al; Department of Pediatrics, Baylor College of Medicine, Houston, TX; 77030, USA.; OBJECTIVES. To determine the pharmacokinetic properties, tolerance, safety, and preliminary activity of stavudine in human immunodeficiency virus (HIV)-infected children. DESIGN. Phase I/II, open and dose-ranging (0.125 to 4 mg/kg/day in two divided doses). PATIENTS. Thirty-seven HIV-infected children (median age, 5.5
HIV/age of first sexual encounter [letter; comment]: Pediatrics. 1995 Aug;96(2 Pt 1):377. Unique Identifier : AIDSLINE MED/95357137; Adams J; Friedman LS; Mason V; Rice L
Starring role [news]: Nurs Times. 1995 Jun 21-7;91(25):18. Unique Identifier : AIDSLINE MED/95357184; Trevelyan J
HIV transmission in sexual networks: an empirical analysis.: Proc R Soc Lond B Biol Sci. 1995 Jun 22;260(1359):237-44. Unique Identifier : AIDSLINE MED/95357362; Service Sk; Blower SM; Department of Psychiatry, University of California San Francisco; 94143, USA.; Risk behaviour and egocentric sexual network data collected from a large random sample of young gay men in San Francisco were analysed to assess the importance of sexual mixing (i.e. sexual networks) in the acquisition of HIV. These data were collected in 1993, during wave one of a longitudinal cohort study of HIV tra
The population dynamics of vertically and horizontally transmitted parasites.: Proc R Soc Lond B Biol Sci. 1995 Jun 22;260(1359):321-7. Unique Identifier : AIDSLINE MED/95357368; Lipsitch M; Nowak MA; Ebert D; May RM; Department ofZoology, University of Oxford, U.K.; We analyse a model of the transmission dynamics of a parasite transmitted both vertically and horizontally. The basic reproductive ratio (R0) of the parasite is shown to be a sum of horizontal and vertical components. We derive expressions for the equilibrium prevalence of infection for a mixture of horizontal and ver
An overview of the effectiveness and efficiency of HIV prevention programs.: Public Health Rep. 1995 Mar-Apr;110(2):134-46. Unique Identifier : AIDSLINE MED/95357460; Holtgrave DR; Qualls NL; Curran JW; Valdiserri RO; Guinan ME; Parra WC; Office of the Associate Director for HIV/AIDS, Centers for; Disease Control and Prevention (CDC), Atlanta, GA, USA.; Because of the enormity of the HIV-AIDS epidemic and the urgency for preventing transmission, HIV prevention programs are a high priority for careful and timely evaluations. Information on program effectiveness and efficiency is needed for decision-making about future HIV prevention priorities. General characteristics
What incentives are effective rewards for 'hidden populations' interviewed as a part of research projects? [letter; comment]: Public Health Rep. 1995 Mar-Apr;110(2):178. Unique Identifier : AIDSLINE MED/95357466; Cottler LB; Compton WM; Keating S
$15 million study launched to improve HIV-AIDs care [news]: Public Health Rep. 1995 Mar-Apr;110(2):226. Unique Identifier : AIDSLINE MED/95357474; Morse SA
NHSC issues notebooks on community primary care [news]: Public Health Rep. 1995 Mar-Apr;110(2):227-8. Unique Identifier : AIDSLINE MED/95357475
Systemic and secretory humoral immunity in the normal human vaginal tract.: Scand J Immunol. 1995 Aug;42(2):269-74. Unique Identifier : AIDSLINE MED/95357644; Hocini H; Barra A; Belec L; Iscaki S; Preud'homme JL; Pillot J; Bouvet JP; Department of Microbial Immunology, Institut Pasteur, Paris,; France.; The molecular status of Abs in the vaginal fluid is reconsidered as a basis for immunization strategies for women vaccination against HIV. Analysis of separated immunoglobulins (Igs) shows a large proportion of uncleaved IgG, whereas the low amount of IgA includes SIgA, monomers and fragments. SIgM is at a very low l
Thrombotic thrombocytopenic purpura and HIV infection [letter; comment]: South Med J. 1995 Aug;88(8):892. Unique Identifier : AIDSLINE MED/95357712; Anand A; Anand A
Will human immunodeficiency virus p24 antigen screening increase the safety of the blood supply and, if so, at what cost? [editorial]: Transfusion. 1995 Jul;35(7):536-9. Unique Identifier : AIDSLINE MED/95357872; Busch MP; Alter HJ
How much would the safety of blood transfusion be improved by including p24 antigen in the battery of tests? [published erratum appears in Transfusion 1996 Feb;36(2):191]: Transfusion. 1995 Jul;35(7):542-7. Unique Identifier : AIDSLINE MED/95357874; Le Pont F; Costagliola D; Rouzioux C; Valleron AJ; Biomathematiques, Biostatistique, Bioinformatique et; Epidemiologie INSERM Unite, Faculte de Medicine; Saint-Antoine, Paris, France.; BACKGROUND: Because p24 antigen may be detectable during seroconversion, before antibodies, some of the infected blood undetected by antibody screening could be identified through antigen screening. STUDY DESIGN AND METHODS: The potential benefit of antigen screening was evaluated in a simulation model incorporating p
The Canadian Hemophilia Registry as the basis for a national system for monitoring the use of factor concentrates [see comments]: Transfusion. 1995 Jul;35(7):548-51. Unique Identifier : AIDSLINE MED/95357875; Walker I; Pai M; Akabutu J; Ritchie B; Growe G; Poon MC; Card R; Ali K; Israels S; Teitel J; et al; Association of Hemophilia Clinic Directors of Canada, Toronto,; Ontario.; BACKGROUND: Canada s publicly funded blood system has recently introduced high-purity concentrates as the standard treatment for individuals with hemophilia. The added cost and the need to document patient outcomes have prompted the consideration of a national blood product monitoring system. STUDY DESIGN AND METHODS:
Contribution of polymerase chain reaction and radioimmunoprecipitation assay in the confirmation of human T-lymphotropic virus infection in French blood donors. Retrovirus Study Group of the French Society of Blood Transfusion.: Transfusion. 1995 Jul;35(7):596-600. Unique Identifier : AIDSLINE MED/95357884; Defer C; Coste J; Descamps F; Voisin S; Lemaire JM; Maniez M; Courouce AM; Centre Regionaux de Transfusion Sanguine, Lille, France.; BACKGROUND: To verify the criteria for human T-lymphotropic virus (HTLV) seropositivity in Western blot (WB) proposed by the Retrovirus Study Group of the French Society of Blood Transfusion, 186 blood donations that were repeatedly reactive in HTLV enzyme-linked immunosorbent assay, selected according to their WB pat
Transfusion practices in human immunodeficiency virus-infected patients.: Transfusion. 1995 Jul;35(7):612-6. Unique Identifier : AIDSLINE MED/95357887; Popovsky MA; Benson K; Glassman AB; Hume H; Oberman HA; Pisciotto PT; Anderson KC; American Red Cross Blood Services, New England Region, Dedham,; Massachusetts, USA.; BACKGROUND: The reported immunomodulatory effects of transfusion raise concern about the potential for virus activation and tumor growth in human immunodeficiency virus (HIV)-infected patients. In the absence of standards of transfusion practice for such patients, a survey of transfusion policies among institutions sp
Patterns of care for and outcomes of Pneumocystis carinii pneumonia among persons with transfusion-acquired AIDS.: Transfusion. 1995 Aug;35(8):674-8. Unique Identifier : AIDSLINE MED/95357899; Bennett CL; Horner RD; Aboulafia D; Weinstein RA; Division of Health Services Research, Lakeside Veterans; Administration Hospital, USA.; BACKGROUND: The most common human immunodeficiency virus (HIV)-related cause of death in persons with transfusion-acquired (TA) AIDS has been Pneumocystis carinii pneumonia (PCP). While better treatment for PCP accounts for improved survival among HIV-infected homosexual or bisexual men, the extent to which others hav
Protection of macaques against simian immunodeficiency virus infection with inactivated vaccines: comparison of adjuvants, doses and challenge viruses. The European Concerted Action on 'Macaque Models for AIDS Research'.: Vaccine. 1995 Feb;13(3):295-300. Unique Identifier : AIDSLINE MED/95358023; Nine European laboratories contributed a total of 98 macaques towards a collaborative trial to study the ability of formaldehyde-inactivated or subunit SIV vaccines to protect immunized animals against live virus challenges. Four adjuvants, three dose levels and two immunization schedules were compared. Fifty-two of 6
Neutralizing antibodies against highly cytopathic Zairian human immunodeficiency type-1 virus (HIV-1) NDK are present in sera outside Africa.: Vaccine. 1995 Feb;13(3):321-5. Unique Identifier : AIDSLINE MED/95358028; Machado AA; Bakpabua M; Salaun D; de Mareuil J; Krchnak V; MacGregor RR; Chermann JC; Hirsch I; INSERM U322, Unite de Recherches sur les Retrovirus et; Maladies, Associees, Marseille, France.; The prototype virus HIV-1 LAV and highly cytopathic Zairian virus HIV-1 NDK belong to the genetic subtypes B and D and represent low and highly cytopathic phenotypes, respectively. Their neutralization pattern and serotype were studied with respect to differences in their genotypes and phenotypes. Sera from HIV-1-infe
HIV-1 group O infection in Belgium.: Acta Clin Belg. 1995;50(3):171-3. Unique Identifier : AIDSLINE MED/95358040; Peeters M; Lobe V; Nkengasong J; Willems B; Delforge ML; Van Renterghem L; Revets H; Sprecher S; van der Groen G; Institute of Tropical Medicine, Department of Microbiology,; Antwerp, Belgium.
Pleural effusions in human immunodeficiency virus-infected patients. Correlation with concomitant pulmonary diseases.: Acta Cytol. 1995 Jul-Aug;39(4):698-700. Unique Identifier : AIDSLINE MED/95358054; Armbruster C; Schalleschak J; Vetter N; Pokieser L; IInd Medical Department, Pulmologisches Zentrum Vienna, Austria.; The objective of our study was to evaluate the prevalence of pleural effusions in patients with the acquired immunodeficiency syndrome, to correlate these effusions with any concomitant pulmonary diseases and to evaluate the role of cytologic examination in the diagnosis of the effusions. Twenty-eight of 389 (7.2%) hu
Penicillium marneffei infection in patients infected with the human immunodeficiency virus. A report of two cases.: Acta Cytol. 1995 Jul-Aug;39(4):798-802. Unique Identifier : AIDSLINE MED/95358073; Remadi S; Lotfi C; Finci V; Ismail A; Rogiano D; Vassilakos P; Seemayer TA; Institut de pathologie clinique, Hopital Cantonal, Universitaire; de Geneve, Switzerland.; We present the cytologic and histologic features of two cases of Penicillium marneffei (PM) infection occurring in human immunodeficiency virus-positive patients following a journey to endemic areas. PM closely resembles Histoplasma capsulatum, in both its morphology and tissue reactions. Distinctive histologic featur
Cryptococcal lymphadenitis: fine needle aspiration in acquired immunodeficiency syndrome [letter]: Acta Cytol. 1995 Jul-Aug;39(4):840-1. Unique Identifier : AIDSLINE MED/95358085; Trivino A; de los Heros C; Claros I; Onrubia JA; Zapatero AH
AIDS and tuberculosis/leprosy in Nigeria: the urbanisation factor.: Acta Leprol. 1995;9(3):149-51. Unique Identifier : AIDSLINE MED/95358101; Awofeso N; Kaduna State Tuberculosis and Leprosy Control Services, Zaria,; Nigeria.; A study was conducted between February and June 1994 on the influence of urbanisation on the seroprevalence of human immunodeficiency virus (HIV) amongst tuberculosis (TB) and leprosy patients in the 4 Primary Health Care Zones in Nigeria . Results indicate that 71.4% of all smear
Prognostic factors for all-cause mortality among hemophiliacs infected with human immunodeficiency virus.: Am J Epidemiol. 1995 Aug 1;142(3):304-13. Unique Identifier : AIDSLINE MED/95358149; Diamondsstone LS; Blakley SA; Rice JC; Clark RA; Goedert JJ; Viral Epidemiology Branch, National Cancer Institute, Rockville,; MD 20852, USA.; To identify the prognostic significance of hemophilia- and virus-related factors, the authors undertook a survival analysis among 644 human immunodeficiency virus (HIV)-infected subjects enrolled in the Multicenter Hemophilia Cohort Study between 1985 and 1993. Acquired immunodeficiency syndrome (AIDS) was the leading
Temporal trends in human immunodeficiency virus seroprevalence and sexual behavior at the San Francisco municipal sexually transmitted disease clinic, 1989-1992.: Am J Epidemiol. 1995 Aug 1;142(3):314-22. Unique Identifier : AIDSLINE MED/95358150; Schwarcz SK; Kellogg TA; Kohn RP; Katz MH; Lemp GF; Bolan GA; AIDS Office, San Francisco Department of Public Health, CA 94102,; USA.; The authors analyzed temporal trends in human immunodeficiency virus (HIV) infection among men and women who visited the San Francisco municipal sexually transmitted disease clinic between 1989 and 1992, using blinded HIV seroprevalence data. Temporal changes in sexual behavior were evaluated by abstracting self-repor
The Multicenter AIDS Cohort Study: retention after 9 1/2 years.: Am J Epidemiol. 1995 Aug 1;142(3):323-30. Unique Identifier : AIDSLINE MED/95358151; Dudley J; Jin S; Hoover D; Metz S; Thackeray R; Chmiel J; Department of Epidemiology, School of Public Health, University; of California, Los Angeles 90024, USA.; In a longitudinal, multicenter study of 4,954 men at risk for human immunodeficiency virus infection and acquired immunodeficiency syndrome, data from the first 9.5 years of follow-up (April 1984 through September 1993) were used to determine differences between those who remained in the study and those who dropped ou
Seroepidemiology of hepatitis B virus in a population of injecting drug users. Association with drug injection patterns.: Am J Epidemiol. 1995 Aug 1;142(3):331-41. Unique Identifier : AIDSLINE MED/95358152; Levine OS; Vlahov D; Koehler J; Cohn S; Spronk AM; Nelson KE; Department of Epidemiology, School of Hygiene and Public Health,; The Johns Hopkins University, Baltimore, MD 21205, USA.; To investigate the epidemiology of hepatitis B virus (HBV) infection among injecting drug users, the authors assessed the prevalence of HBV seromarkers among 2,558 injecting drug users recruited through street outreach in Baltimore, Maryland, in 1988-1989. Eighty percent of the drug users had at least one HBV seromark
Case report: vitamin D-mediated hypercalcemia in fungal infections.: Am J Med Sci. 1995 Aug;310(2):71-6. Unique Identifier : AIDSLINE MED/95358162; Spindel SJ; Hamill RJ; Georghiou PR; Lacke CE; Green LK; Mallette LE; Section of Infectious Disease, Veterans Affairs Medical Center,; Houston, TX 77030, USA.; Hypercalcemia has been well described in a variety of neoplastic and granulomatous diseases. One mechanism for this hypercalcemia is via the excess production of 1,25-dihydroxyvitamin D from extra-renal sources. The authors describe an AIDS patient infected with Cryptococcus neoformans who had suggestive evidence of v
Crossing the black ocean. For many AIDS patients, the journey toward death is too long.: Am J Nurs. 1995 Aug;95(8):72. Unique Identifier : AIDSLINE MED/95358179; Schmidt J; AIDS Services, Visiting Nurse Service of New York, New York City,; USA.
Missing babies [letter]: Anesthesiology. 1995 Aug;83(2):436. Unique Identifier : AIDSLINE MED/95358515; Schiff-Keren B
[Chronic herpes resistant to acyclovir in a patient with AIDS]: Ann Dermatol Venereol. 1994;121(11):810-3. Unique Identifier : AIDSLINE MED/95358532; About I; Capdeville J; Bernard P; Massip P; Service Medecine Interne, Hopital de Foix.; INTRODUCTION. The prevalence of mucocutaneous herpetic infection is especially high in patients with the acquired immunodeficiency syndrome (AIDS). In these patients, 8 p. 100 of the chronic or recurrent herpetic lesions are due to a mutant strain. CASE REPORT. A case of very large (900 cm2) genital chronic herpetic i
[Necrotizing vasculitis induced by cytomegalovirus in a woman with acquired immunodeficiency syndrome]: Ann Dermatol Venereol. 1994;121(11):820-2. Unique Identifier : AIDSLINE MED/95358535; Ghigliotti G; Canessa A; Pastorino A; Mazzarello G; De Marchi R; Gambini C; Division de Dermatologie de l'Hopital San Martino, Genes.; INTRODUCTION: Skin lesions induced by cytomegalovirus are rare and usually non-characteristic. CASE REPORT: A 32-year-old women with AIDS developed about twenty unpainful ulceronecrotic lesions on the extension aspect of the members and the trunk. Histology examination and in situ
[Photosensitivity, photocarcinogenesis and phototherapy in acquired immunodeficiency syndrome]: Ann Dermatol Venereol. 1994;121(11):844-9. Unique Identifier : AIDSLINE MED/95358540; Thomas P; Ehrsam E; Clinique dermatologique B, Hopital C.-Huriez, Lille.
Bacillary angiomatosis presenting as a malleolar ulcer [letter]: Arch Dermatol. 1995 Aug;131(8):963-4. Unique Identifier : AIDSLINE MED/95358621; Carrascosa JM; Ribera M; Bielsa I; Raventos A; Vaquero M; Ferrandiz C
Enhancement by hydroxyurea of the anti-human immunodeficiency virus type 1 potency of 2'-beta-fluoro-2',3'-dideoxyadenosine in peripheral blood mononuclear cells.: Biochem Pharmacol. 1995 Jul 17;50(2):274-6. Unique Identifier : AIDSLINE MED/95358722; Gao WY; Mitsuya H; Driscoll JS; Johns DG; Experimental Retrovirology Section, NCI, National Institutes of; Health, Bethesda, MD 20982, USA.; Ribonucleotide reductase inhibitors such as hydroxyurea (HU) and related compounds, at low, non-toxic doses, enhance the anti-human immunodeficiency virus type 1 (HIV-1) potency of both purine and pyrimidine 2 ,3 -dideoxynucleosides (ddNs) in human lymphocytes and macrophages. The most marked enhancement of inhibition
Characteristics of persons with late AIDS diagnosis in the United States.: Am J Prev Med. 1995 Mar-Apr;11(2):114-9. Unique Identifier : AIDSLINE MED/95358888; Hu DJ; Byers R Jr; Fleming PL; Ward JW; Division of HIV/AIDS, National Center for Infectious Diseases,; Centers for Disease Control and Prevention, Atlanta, GA 30333,; USA.; To describe characteristics of persons with late (at or after death) acquired immunodeficiency syndrome (AIDS) diagnosis, we analyzed national surveillance data among all persons with AIDS diagnosed through December 1991 under the pre-1993 AIDS case definition and with a known date of death. Late diagnosis was present
Sequence similarities between latent membrane protein LMP-1 of Epstein-Barr virus, integral membrane protein p12I of human T cell leukemia/lymphotropic virus type 1, E5 transformation protein of bovine papillomavirus, and the transmembrane proteins of slowly transforming retroviruses [letter]: AIDS Res Hum Retroviruses. 1995 Apr;11(4):431-2. Unique Identifier : AIDSLINE SWISSPROT; Garry RF
Phagocytosis of individual CD4+ T cells by HIV-induced T cell syncytia.: AIDS Res Hum Retroviruses. 1995 Apr;11(4):433-42. Unique Identifier : AIDSLINE MED/95358903; Murphy S; Sylwester A; Kennedy RC; Soll DR; Department of Biological Sciences, University of Iowa, Iowa City; 52242, USA.; Transmission electron microscopic analysis of HIV-induced syncytia of the CD4+ SupT1 cell line has revealed profiles of whole T cells in the syncytium cytoplasm. Serial sections demonstrate that these T cells are completely enveloped by a second membrane in the syncytium cytoplasm and represent phagosomes. Pycnosis of
HIV type 1 Tat protein induces apoptosis and death in Jurkat cells.: AIDS Res Hum Retroviruses. 1995 Apr;11(4):443-50. Unique Identifier : AIDSLINE MED/95358904; Purvis SF; Jacobberger JW; Sramkoski RM; Patki AH; Lederman MM; Department of Environmental Health Sciences, Case Western Reserve; University School of Medicine, Cleveland, Ohio 44106, USA.; Jurkat cells stably expressing high levels of the HIV-1 Tat protein were generated after transfection with an Epstein-Barr virus-based episomal replicon and selection in hygromycin B. The Jurkat Tat transfectants exhibited a longer doubling time when compared to Jurkat cells or Jurkat cells transfected with the contro
Cystamine inhibits HIV type 1 replication in cells of monocyte/macrophage and T cell lineages.: AIDS Res Hum Retroviruses. 1995 Apr;11(4):451-9. Unique Identifier : AIDSLINE MED/95358905; Ho WZ; Zhu XH; Song L; Lee HR; Cutilli JR; Douglas SD; Division of Allergy, Immunology and Infectious Diseases,; Children's Hospital of Philadelphia, University of Pennsylvania; Medical School 19104, USA.; The effects of cysteamine (2-aminoethanethiol, MEA) and its disulfide, cystamine, on the human immunodeficiency virus (HIV-1) expression in chronically infected promonocytic cells (U1), T cell line (ACH-2), and peripheral blood monocyte-derived macrophages (MDM) were investigated. U1 and ACH-2 cells constitutively exp
Distinct changes in HIV type 1 RNA versus p24 antigen levels in serum during short-term zidovudine therapy in asymptomatic individuals with and without progression to AIDS.: AIDS Res Hum Retroviruses. 1995 Apr;11(4):473-9. Unique Identifier : AIDSLINE MED/95358907; Jurriaans S; Weverling GJ; Goudsmit J; Boogaard J; Brok M; Van Strijp D; Lange J; Koot M; Van Gemen B; Human Retrovirus Laboratory, Academic Medical Center, University; of Amsterdam, The Netherlands.; Serum HIV-1 RNA and p24 antigen levels were examined in 28 seropositive asymptomatic individuals participating in a trial on the efficacy of zidovudine. Sixteen individuals remained asymptomatic until 4 years after the onset of the trial, whereas 12 individuals were diagnosed with an AIDS-defining event. The serum HIV
Anti-HIV type 1 cytotoxic T lymphocyte effector activity and disease progression in the first 8 years of HIV type 1 infection of homosexual men.: AIDS Res Hum Retroviruses. 1995 Apr;11(4):481-9. Unique Identifier : AIDSLINE MED/95358908; Rinaldo CR Jr; Beltz LA; Huang XL; Gupta P; Fan Z; Torpey DJ 3rd; Department of Pathology, University of Pittsburgh School of; Medicine, Pennsylvania 15261, USA.; Cytotoxic T lymphocytes (CTL) may play an important role in host defense against HIV-1 infection. In this study, we examined the responses of circulating effector CTL (CTLe) specific for Gag, Pol, Env, and Tat in 57 HIV-1-infected men, 49 of whom were asymptomatic and had documented time since seroconversion of
Neutralizing monoclonal antibody against a external envelope glycoprotein (gp110) of SIVmac251.: AIDS Res Hum Retroviruses. 1995 Apr;11(4):501-8. Unique Identifier : AIDSLINE MED/95358910; Matsumi S; Matsushita S; Yoshimura K; Javaherian K; Takatsuki K; Second Department of Internal Medicine, Kumamoto University; School of Medicine, Japan.; Three monoclonal antibodies (M318T, M56S and M815) against an external envelope glycoprotein (gp110) of simian immunodeficiency virus (SIV) mac251 were obtained by immunizing BALB/c mice with recombinant gp110 (rgp110). All three monoclonal antibodies reacted with the surface of cells infected with SIVmac251 but not w
Production of a human anti-CD4 monoclonal antibody with antiidiotype to anti-HIV type 1 glycoprotein 120.: AIDS Res Hum Retroviruses. 1995 Apr;11(4):509-15. Unique Identifier : AIDSLINE MED/95358911; Karpatkin S; Nardi MA; Liu LX; Kouri YH; Borkowsky W; Department of Medicine, New York University Medical Center, New; York 10016, USA.; Human anti-CD4 IgG antibodies from 3 HIV-1-infected patients were affinity purified and shown to inhibit HIV-1 binding and infection of HBP-T cells. Lymphocytes from patient A, whose anti-CD4 inhibited HIV-1 binding by 68% and infection by 72%, were cultured and transformed with EBV. A human monoclonal antiidiotype an
In vivo administration of CD4-specific monoclonal antibody: effect on provirus load in rhesus monkeys chronically infected with the simian immunodeficiency virus of macaques.: AIDS Res Hum Retroviruses. 1995 Apr;11(4):517-25. Unique Identifier : AIDSLINE MED/95358912; Reimann KA; Cate RL; Wu Y; Palmer L; Olson D; Waite BC; Letvin NL; Burkly LC; Harvard Medical School, Beth Israel Hospital, Boston,; Massachusetts 02215, USA.; Since monoclonal antibodies (MAb) specific for CD4 are potent inhibitors of HIV and SIV replication in vitro, we explored their potential usefulness in vivo as an AIDS therapy. The anti-CD4 MAb 5A8 binds to domain 2 of the CD4 molecule and inhibits virus replication and virus-induced cell fusion at a postvirus binding
An expanded search for human infection with simian type D retrovirus.: AIDS Res Hum Retroviruses. 1995 Apr;11(4):527-9. Unique Identifier : AIDSLINE MED/95358913; Lerche NW; Heneine W; Kaplan JE; Spira T; Yee JL; Khabbaz RF; Virology and Immunology Unit, California Regional Primate; Research Center, University of California, Davis 95616, USA.
Analysis of a feline immunodeficiency virus provirus reveals patterns of gene sequence conservation distinct from human immunodeficiency virus type 1.: AIDS Res Hum Retroviruses. 1995 Apr;11(4):531-3. Unique Identifier : AIDSLINE GENBANK/U11820; Sodora DL; Courcelle J; Brojatsch J; Berson A; Wang YC; Dow SW; Hoover EA; Mullins JI; Department of Microbiology and Immunology, Stanford University; School of Medicine, CA 94305, USA.
HIV awareness and needlestick injuries [letter; comment]: Br Dent J. 1995 Jul 22;179(2):48. Unique Identifier : AIDSLINE MED/95358918; Day RM
HIV awareness and needlestick injuries [letter; comment]: Br Dent J. 1995 Jul 22;179(2):48. Unique Identifier : AIDSLINE MED/95358919; Erridge PL
HIV rate up as young gay men ignore safe sex advice [news]: Nurs Stand. 1995 Jul 19-25;9(43):12. Unique Identifier : AIDSLINE MED/95359014
Characterization of dextromoramide (Palfium) abuse by hair analysis in a denied case.: Int J Legal Med. 1995;107(5):269-72. Unique Identifier : AIDSLINE MED/95359059; Kintz P; Cirimele V; Edel Y; Tracqui A; Mangin P; Institut de Medecine Legale, Strasbourg, France.; By providing information on exposure to drugs over time, hair analysis is useful in verifying the history of drug use. In a clinical case, where drug abuse was denied, it was possible to identify dextromoramide in the hair of the subject. After acid hydrolysis of the hair with 0.1 M HCl, in the presence of SKF 525A as
Reducing the risk of blood borne infection in surgical practice.: Br J Obstet Gynaecol. 1995 Jun;102(6):439-41. Unique Identifier : AIDSLINE MED/95359086; Stafford MK; Kitchen VS; Smith JR; Department of Genitourinary Medicine and Communicable Diseases,; St. Mary's Hospital Medical School, London.
Solution structure of the DNA binding domain of HIV-1 integrase.: Biochemistry. 1995 Aug 8;34(31):9826-33. Unique Identifier : AIDSLINE MED/95359147; Lodi PJ; Ernst JA; Kuszewski J; Hickman AB; Engelman A; Craigie R; Clore GM; Gronenborn AM; Laboratory of Chemical Physics, National Institute of Diabetes; and Digestive and Kidney Diseases, National Institutes of Health,; Bethesda, Maryland 20892-0520, USA.; The solution structure of the DNA binding domain of HIV-1 integrase (residues 220-270) has been determined by multidimensional NMR spectroscopy. The protein is a dimer in solution, and each subunit is composed of a five-stranded beta-barrel with a topology very similar to that of the SH3 domain. The dimer is formed by
Different affinity of the two forms of human cytosolic thymidine kinase towards pyrimidine analogs.: Biochim Biophys Acta. 1995 Jul 19;1250(2):158-62. Unique Identifier : AIDSLINE MED/95359189; Munch-Petersen B; Tyrsted G; Cloos L; Beck RA; Eger K; Department of Biology and Chemistry, Roskilde University,; Denmark.; Recent results showed that ATP enables a kinetically slow shift from a low affinity form to a high affinity form of human cytosolic thymidine kinase (TK1), as reflected by the respective apparent Km values for thymidine of 15 microM and 0.7 microM. The shift is dependent on the concentration of enzyme protein, and cal
Tuberculosis surveillance in a therapeutic community.: J Addict Dis. 1995;14(1):55-65. Unique Identifier : AIDSLINE MED/95359220; Foley ME; Ehr AP; Raza B; Devlin CJ; Department of Community Medicine, Mount Sinai School of Medicine,; New York, NY 10029, USA.; Tuberculosis, a chronic communicable bacterial infection of epidemic proportions in the United States , is more common among debilitated and immunocompromised persons, for example, alcoholics, drug abusers, and HIV/AIDS patients, than among the general population. Daytop Village Inc., a
AIDS' impact. 2nd International Conference on Biopsychological Aspects of HIV and AIDS. Brighton, UK, 7-10 July 1994. Proceedings.: AIDS Care. 1995;7 Suppl 1:S1-104. Unique Identifier : AIDSLINE MED/95359254
Why we need to rethink AIDS education for gay men.: AIDS Care. 1995;7 Suppl 1:S11-9. Unique Identifier : AIDSLINE MED/95359255; Gold R; School of Psychology, Deakin University, Victoria, Australia.; This paper examines critically the issue of prevention of HIV infection for gay men. Evidence for the persistence of unsafe sexual behaviour in gay men is provided, followed by discussion of obstacles to the development of effective interventions to initiate and maintain safer sex behaviour.
Reaching male clients of female prostitutes: the challenge for HIV prevention.: AIDS Care. 1995;7 Suppl 1:S21-32. Unique Identifier : AIDSLINE MED/95359256; Faugier J; Cranfield S; Community Nursing Professional Unit, University of Manchester,; Newton Health Health Centre, UK.; Male clients of prostitutes have proved to be a very difficult group to access for the purposes of HIV research and education. Prevention initiatives to date have placed less emphasis on HIV awareness with this potential target group and more on empowering prostitutes to control the sexual transaction with clients. Da
Gender differences in HIV-related psychological distress in heterosexual couples.: AIDS Care. 1995;7 Suppl 1:S33-8. Unique Identifier : AIDSLINE MED/95359257; Kennedy CA; Skurnick JH; Foley M; Louria DB; University of Medicine and Dentistry of New Jersey, New Jersey; Medical School-Department of Preventive Medicine, Newark 07103,; USA.; In order to determine the effect of family support on the psychological well-being of heterosexual couples with at least one HIV-seropositive, family support data were obtained from couples, who were separately interviewed. Two hundred heterosexuals were interviewed (97 males, 103 females). 182 were partners in HIV se
Differences in HIV testing, knowledge and attitudes in pregnant women who deliver and those who terminate: Prevagest 1992--France.: AIDS Care. 1995;7 Suppl 1:S39-46. Unique Identifier : AIDSLINE MED/95359258; Rey D; Moatti JP; Obadia Y; Rotily M; Dellamonica P; Gillet JY; Gastaut JA; South-Eastern French Centre for Disease Control, Marseille.; The object of this study supported by the French Agency for AIDs Research (ANRS) was to assess knowledge and attitudes of pregnant women towards HIV infection and testing, and to compare them according to the outcome of the pregnancy (elective abortion vs delivery). Between March 22 and April 26, 1992, all women endin
'Life' for a non-progressor.: AIDS Care. 1995;7 Suppl 1:S5-9. Unique Identifier : AIDSLINE MED/95359260; Grimshaw J; A non-progressor with HIV, diagnosed in 1984, comments from a personal perspective on how people with HIV are affected by social and professional attitudes. The failure of some professionals to develop an understanding of HIV beyond their own particular field of expertise contributes to the disempowerment experienced
Orphans of the HIV epidemic: unmet needs in six US cities.: AIDS Care. 1995;7 Suppl 1:S57-62. Unique Identifier : AIDSLINE MED/95359261; Levine C; Orphan Project, New York, NY 10013, USA.; In the United States , an estimated 72,000-125,000 children and adolescents will lose their mothers to AIDS by the year 2000. Six cities have been particularly hard hit: New York City, Newark, Miami, San Juan, Los Angeles, and Washington, DC. The most urgent unmet needs for children, th
Caring for people with AIDS in a Nigerian teaching hospital: staff attitudes and knowledge.: AIDS Care. 1995;7 Suppl 1:S63-72. Unique Identifier : AIDSLINE MED/95359262; Adelekan ML; Jolayemi SO; Ndom RJ; Adegboye J; Babatunde S; Tunde-Ayimode M; Yusuff O; Makanjuola AB; Department of Behavioural Sciences, University of Ilorin Teaching; Hospital, Ilorin-Kwara State, Nigeria.; Health workers (HWs) play a pivotal role in preventative programmes being implemented to combat the steady increase in the prevalence of HIV infection and AIDS in Nigeria . We report on a questionnaire survey conducted in October, 1993 among 111 doctors, 92 nurses and 53 non-health
Analysis of psychiatric consultations in patients with HIV infection and related syndromes.: AIDS Care. 1995;7 Suppl 1:S73-7. Unique Identifier : AIDSLINE MED/95359263; Grassi L; Pavanati M; Bedetti A; Bicocchi R; Servizio di Psichiatria di Consulenza e Collegamento, Universita; di Ferrara, Italy.; Patients referred to the consultation-liaison psychiatry department of the University of Ferrara over a 12 month period were studied. About 13% of referrals concerned HIV patients. Comparison of HIV infected with non-HIV infected referrals revealed differences in the reasons for psychiatric consultation and the diagno
Commitment, value conflicts and role strains among French GPs in care for HIV positive patients.: AIDS Care. 1995;7 Suppl 1:S79-84. Unique Identifier : AIDSLINE MED/95359264; Morin M; Obadia Y; Moatti JP; Souville M; Laboratory of Social-Psychology, University of Provence, Aix en; Provence, France.; A survey was carried out on a random sample of GPs in the city of Marseille. 18.5% had been involved during the past year in a regular follow-up of HIV patients. They were in charge with 79.8% of all ambulatory care of HIV+ patients. Those informally specialized professionals were connected to health networks (not o
Relationship between safe sex and acculturation into the gay subculture.: AIDS Care. 1995;7 Suppl 1:S85-8. Unique Identifier : AIDSLINE MED/95359265; Seibt AC; Ross MW; Freeman A; Krepcho M; Hedrich A; McAlister A; Fernandez-Esquer ME; Centre for Applied Health Sciences, University of Luneburg,; Germany.; There is some evidence, although conflicting, to suggest that socialization or acculturation into the gay community is associated with lower levels of unsafe sex. We attempted to determine the relationship between acculturation and sexual safety. We examined data from 282 men (from the Dallas AIDS Community Demonstrat
Risk behaviours of inmates in south-eastern France.: AIDS Care. 1995;7 Suppl 1:S89-93. Unique Identifier : AIDSLINE MED/95359266; Rotily M; Galinier-Pujol A; Vernay-Vaisse C; South-Eastern French Centre for Disease Control, Marseille.; This study was set up to compare risk behaviours between IDU and no-IDU inmates and among IDUs and to elicit the differences of preventive and risk behaviours according to sex. It was carried out in the Baumettes Prison, France , from November 16 to December 21, 1992; 295 male and 1
Health care personnel's critique on the Philippines' first movie on AIDS.: AIDS Care. 1995;7 Suppl 1:S95-8. Unique Identifier : AIDSLINE MED/95359267; Zaldivar SB; Research Institute for Tropical Medicine, Department of Health,; Philippines.; The Dolzura Cortez Story was the Philippines first movie on AIDS that provided a name and a face among the 50 recorded lives that were lost to AIDS in 1992. This movie was utilized as a focus of discussion by some health care personnel to express their thoughts, opinions and recommendations regarding the use of cin
An assessment of self-esteem in HIV-positive patients.: AIDS Care. 1995;7 Suppl 1:S99-104. Unique Identifier : AIDSLINE MED/95359268; Visintini R; Bagnato M; Campanini E; Fontana S; Fossati A; Novella L; Maffei C; Department of Neuropsychic Sciences, Scientific Institute San; Raffaele, Milan, Italy.; The objective of this research is to assess how self-esteem levels differ in HIV-infected subjects in three different risk behaviours: drug addicts, homosexuals, heterosexuals. The sample (n = 104) consisted of: drug addicts (n = 46); homosexual (n = 26); heterosexuals (n = 32). The Rosenberg Self-Esteem Scale (RSES)
Dual-specificity interaction of HIV-1 TAR RNA with Tat peptide-oligonucleotide conjugates.: Bioconjug Chem. 1995 May-Jun;6(3):292-5. Unique Identifier : AIDSLINE MED/95359277; Tung CH; Wang J; Leibowitz MJ; Stein S; Center for Advanced Biotechnology and Medicine, Piscataway, New; Jersey 08854, USA.; An oligonucleotide-peptide conjugate, having dual binding capability for a designated RNA, was designed. The peptide portion of the conjugate interacts with a folded domain in the RNA, whereas the oligonucleotide portion hybridizes with a nearby single-stranded region in the RNA. The dual specificity was proven in a m
[Hygienic aspects of emergency care: principles, requirements and reality]: Anasthesiol Intensivmed Notfallmed Schmerzther. 1995 Jun;30(4):212-9. Unique Identifier : AIDSLINE MED/95359339; Adams HA; Kuhnen E; Schickle-Reim G; Abteilung fur Anasthesie und Intensivmedizin, Marienkrankenhaus; Trier-Ehrang.; In preclinical emergency and rescue medicine, on-target and often improvised and smooth work is essential. Thus, some reductions of clinical standards must be accepted but cannot excuse fundamental mistakes. Hygienic protection of patients and medical staff are both equally important; however, preserving the vital fun
Peripheral T-cell lymphoma in lckpr-bcl-2 transgenic mice.: Blood. 1995 Aug 15;86(4):1255-60. Unique Identifier : AIDSLINE MED/95359417; Linette GP; Hess JL; Sentman CL; Korsmeyer SJ; Department of Medicine, Howard Hughes Medical Institute at; Washington University, St Louis, MO 63110, USA.; t(14;18) is the most common translocation in human lymphoid malignancy and results in bcl-2 overexpression. Bcl-2 blocks apoptosis and constitutes the initial member of a new category of oncogenes, ie, regulators of cell death. Bcl-2-Ig transgenic mice develop follicular hyperplasia and progress to malignant B-cell ly
Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease [see comments]: Blood. 1995 Aug 15;86(4):1276-80. Unique Identifier : AIDSLINE MED/95359420; Soulier J; Grollet L; Oksenhendler E; Cacoub P; Cazals-Hatem D; Babinet P; d'Agay MF; Clauvel JP; Raphael M; Degos L; et al; Laboratoire d'Hematologie Moleculaire, Hopital Saint-Louis,; Paris, France.; Multicentric Castleman s disease (MCD) is an atypical lymphoproliferative disorder defined using clinical and pathologic criteria. A characteristic of the MCD is a close association with Kaposi s sarcoma (KS), which occurs during the clinical course of most human immunodeficiency virus (HIV)-associated MCD cases and a
Inhibition of productive human immunodeficiency virus-1 infection by cobalamins.: Blood. 1995 Aug 15;86(4):1281-7. Unique Identifier : AIDSLINE MED/95359421; Weinberg JB; Sauls DL; Misukonis MA; Shugars DC; Department of Medicine, VA Medical Center, Durham, NC 27705, USA.; Various cobalamins act as important enzyme cofactors and modulate cellular function. We investigated cobalamins for their abilities to modify productive human immunodeficiency virus-1 (HIV-1) infection of hematopoietic cells in vitro. We show that hydroxocobalamin (OH-Cbl), methylcobalamin (Me-Cbl), and adenosylcobala
Interferon maintenance therapy for patients with chronic lymphocytic leukemia in remission after fludarabine therapy.: Blood. 1995 Aug 15;86(4):1298-300. Unique Identifier : AIDSLINE MED/95359424; O'Brien S; Kantarjian H; Beran M; Robertson LE; Koller C; Lerner S; Keating MJ; Department of Hematology, University of Texas M.D. Anderson; Cancer Center, Houston 77030, USA.; Many patients with chronic lymphocytic leukemia (CLL) achieve remission after treatment with fludarabine chemotherapy. Most of these patients, however, later experience relapse. In addition, immunologic deficits may persist even in patients in complete remission; lymphopenia, predominantly involving the CD4 population
Delineation of an immunodominant and human T-cell lymphotropic virus (HTLV)-specific epitope within the HTLV-I transmembrane glycoprotein.: Blood. 1995 Aug 15;86(4):1392-9. Unique Identifier : AIDSLINE MED/95359437; Hadlock KG; Goh CJ; Bradshaw PA; Perkins S; Lo J; Kaplan JE; Khabbaz R; Foung SK; Department of Molecular Virology, Genelabs Technologies, Inc.; Redwood City, CA 94063, USA.; Antibody reactivity to the transmembrane region of human T-cell lymphotropic virus type I (HTLV-I) envelope, gp21, is observed in virtually all individuals infected with HTLV-I or HTLV-II. Recombinant proteins encoding selected portions of gp21 are described and used to define two immunogenic regions. The first epitop
T-cell death by apoptosis in vertically human immunodeficiency virus-infected children coincides with expansion of CD8+/interleukin-2 receptor-/HLA-DR+ T cells: sign of a possible role for herpes viruses as cofactors?: Blood. 1995 Aug 15;86(4):1400-7. Unique Identifier : AIDSLINE MED/95359438; Lauener RP; Huttner S; Buisson M; Hossle JP; Albisetti M; Seigneurin JM; Seger RA; Nadal D; Division of Immunology/Hematology, University Children's; Hospital, Zurich, Switzerland.; One mechanism proposed to play a role in T-cell depletion in human immunodeficiency virus (HIV) infection is apoptosis (activation-induced cell death). We assessed whether apoptosis is related to activation of T cells in vivo and its possible triggers. DNA was extracted from peripheral blood mononuclear cells (PBMC) t
Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry.: Blood. 1995 Aug 15;86(4):1408-19. Unique Identifier : AIDSLINE MED/95359439; Picker LJ; Singh MK; Zdraveski Z; Treer JR; Waldrop SL; Bergstresser PR; Maino VC; Department of Pathology, University of Texas Southwestern Medical; Center, Dallas 75235-9072, USA.; The array of cytokines produced by T cells in effector sites is a primary means by which these cells mediate host defense. It is well recognized that cloned T cells are heterogeneous with regard to cytokine synthesis and, thus, in their ability to mediate specific immune responses, but the extent to which the patterns
Characterization of B-cell lines established from two X-linked severe combined immunodeficiency patients: interleukin-15 binds to the B cells but is not internalized efficiently.: Blood. 1995 Aug 15;86(4):1428-36. Unique Identifier : AIDSLINE MED/95359441; Kumaki S; Ochs HD; Timour M; Schooley K; Ahdieh M; Hill H; Sugamura K; Anderson D; Zhu Q; Cosman D; et al; Department of Molecular Biology, Immunex Research and Development; Corp., Seattle, WA 98101, USA.; X-linked severe combined immunodeficiency (XSCID) is characterized by absent or profoundly reduced numbers of T cells and normal numbers of B cells in the circulation. Affected patients have mutations of the interleukin-2 ( IL-2 ) receptor gamma chain gene. Using Epstein
Human immature thymocytes as target cells of the leukemogenic activity of human T-cell leukemia virus type I.: Blood. 1995 Aug 15;86(4):1444-52. Unique Identifier : AIDSLINE MED/95359443; Maguer-Satta V; Gazzolo L; Dodon MD; Centre National de la Recherche Scientifique/Universite Claude; Bernard, Lyon, France.; The risk of developing adult T-cell leukemia (ATL) associated with neonatal infection by human T-cell leukemia virus type I (HTLV-I) suggests that early events triggered by HTLV-I might be of crucial importance in initiating the multistep lymphoproliferative process leading several decades later to the development of
Cell-free transmission of Fv-4 resistance gene product controlling Friend leukemia virus-induced leukemogenesis: a unique mechanism for interference with viral infection.: Blood. 1995 Aug 15;86(4):1557-63. Unique Identifier : AIDSLINE MED/95359457; Kitagawa M; Aizawa S; Kamisaku H; Ikeda H; Hirokawa K; Sado T; Department of Pathology, Faculty of Medicine, Tokyo Medical and; Dental University, Japan.; Fv-4 is a mouse gene that dominantly confers resistance to infection by ecotropic murine leukemia virus (MuLV). We previously demonstrated that mixed radiation bone marrow chimeras containing Fv-4r-bearing BALB/c-Fv-4Wr (C4W) bone marrow and Fv-4r-bearing C3H/He (C3H) bone marrow grafted into C3H recipient mice (C4W+C
Some thoughts on AIDS and death.: J Clin Ethics. 1995 Spring;6(1):91-2. Unique Identifier : AIDSLINE MED/95359501; Novick A; Yale University, USA.
Legal trends in bioethics [news]: J Clin Ethics. 1995 Spring;6(1):93-6. Unique Identifier : AIDSLINE MED/95359502; Davis DS; Cleveland-Marshall College of Law, Cleveland State University,; Ohio, USA.
Hyperkalemia and high-dose trimethoprim/sulfamethoxazole.: Ann Pharmacother. 1995 Apr;29(4):427-9. Unique Identifier : AIDSLINE MED/95359518; Hsu I; Wordell CJ; Thomas Jefferson University Hospital, Philadelphia, PA 19103,; USA.; Evidence from the literature strongly supports that high doses of TMP, as used in the treatment of PCP in AIDS patients, have the propensity to cause hyperkalemia by inhibiting sodium channels in the distal nephron, thereby impairing potassium secretion. The mechanism of TMP-induced hyperkalemia is believed to be simi
Just a glove?: Br J Theatre Nurs. 1994 Aug;4(5):7, 9-10. Unique Identifier : AIDSLINE MED/95359610; Townsend M; Surgical gloves were introduced in the early years of this century, initially to protect nurses and surgeons hands from the strong antiseptic chemicals used during surgery. William Stewart Halstead is generally credited with introducing gloves to protect his scrub nurse (who later became his wife) from the carbolic
Human immunodeficiency virus infection in Taiwan, 1984 to 1994.: J Formos Med Assoc. 1994 Nov-Dec;93(11-12):901-5. Unique Identifier : AIDSLINE MED/95359737; Chen MY; Wang GR; Chuang CY; Shih YT; Department of Internal Medicine, National Taiwan University; Hospital, Taipei, R.O.C.; From 1984 to September 1994, a total of 9,099,734 serum samples from six population groups were tested for the antibody to human immunodeficiency virus type 1 (HIV). Mandatory testing was carried out for blood donors, military recruits, immigrants and prisoners; other population groups were tested anonymously with con
Risk factors for HIV infection in people attending clinics for sexually transmitted diseases in India.: BMJ. 1995 Jul 29;311(7000):283-6. Unique Identifier : AIDSLINE MED/95359776; Rodrigues JJ; Mehendale SM; Shepherd ME; Divekar AD; Gangakhedkar RR; Quinn TC; Paranjape RS; Risbud AR; Brookmeyer RS; Gadkari DA; et al; National AIDS Research Institute, Pune, India.; OBJECTIVE--To investigate the risk factors for HIV infection in patients attending clinics for sexually transmitted diseases in India . DESIGN--Descriptive study of HIV serology, risk behaviour, and findings on physical examination. SUBJECTS--2800 patients presenting to outpatient cl
Has nursing lost its way? Nursing: no regrets.: BMJ. 1995 Jul 29;311(7000):307-8. Unique Identifier : AIDSLINE MED/95359792; Lempp H; Merton, Sutton and Wandsworth Health Commission, London.
Unsuspected HIV infection in first year of life. Obstetric and perinatal staff should provide sound, unbiased information on HIV tests [letter; comment]: BMJ. 1995 Jul 29;311(7000):328. Unique Identifier : AIDSLINE MED/95359808; Nunns D
Quantitative and qualitative research in the addictions: an unhelpful divide [editorial]: Addiction. 1995 Jun;90(6):749-51; discussion 753-66. Unique Identifier : AIDSLINE MED/95359844; McKeganey N
HIV and prisons.: Natl Med J India. 1995 Jul-Aug;8(4):180-1. Unique Identifier : AIDSLINE MED/95359867; Kohli HS; Department of Public Health, University of Glasgow, Scotland.
HIV-control programme in Thailand.: Natl Med J India. 1995 Jul-Aug;8(4):181-2. Unique Identifier : AIDSLINE MED/95359868; Chowdhury S; Centre for Community Medicine, All India Institute of Medical; Sciences, New Delhi.
[Chronic sputum positive tuberculosis--an epidemiologic problem]: Pneumonol Alergol Pol. 1995;63(1-2):106-9. Unique Identifier : AIDSLINE MED/95359912; Michalowska-Mitczuk D; I Kliniki Gruzlicy i Chorob Pluc, Instytutu Gruzlicy i Chorob; Pluc w Warszawie.
[Drugs used in systemic fungal infections]: Pneumonol Alergol Pol. 1995;63(1-2):115-9. Unique Identifier : AIDSLINE MED/95359914; Wierzbicka M; I Kliniki Gruzlicy i Chorob Pluc, Instytutu Gruzlicy i Chorob; Pluc w Warszawie.
[The role of bronchoscopy and bronchoalveolar lavage in diagnosis of pulmonary tuberculosis in AIDS]: Pneumonol Alergol Pol. 1995;63(1-2):27-31. Unique Identifier : AIDSLINE MED/95359918; Zajaczkowska J; Zalewska-Schonthaler N; Mussabir M; Mydlowska A; Szymanska B; Augustynowicz-Kopec E; Malek L; Kliniki Nabytych Niedoborow Immunologicznych Instytutu, Chorob; Zakaznych i Pasozytniczych AM w Warszawie.; Bronchoscopy was carried out in 32 HIV seropositive patients, most with AIDS during the period between January 1992 and August 1993. In 14 patients tuberculosis was diagnosed, in 13 it was bacteriologically confirmed. The mean age of the examined patients was 35.5 years (range 22-49 years). In 50% of the BAL samples b
[How far should AIDS treatment go (editorial)]: Rev Assoc Med Bras. 1994 Oct-Dec;40(4):231-2. Unique Identifier : AIDSLINE MED/95360065; Amato Neto V; Pasternak J
Physicians' attitudes toward a pediatric notification program of transfusion-related human immunodeficiency virus risk.: Arch Pediatr Adolesc Med. 1995 Aug;149(8):928-30. Unique Identifier : AIDSLINE MED/95360160; McCrindle BW; Newman A; Murphy T; Corey M; Stevens M; Haslam RH; Freedom RM; King SM; Division of Cardiology, Hospital for Sick Children, University of; Toronto, Ontario, Canada.
Corticosteroid therapy for Pneumocystis carinii pneumonia in children with human immunodeficiency virus infection [letter; comment]: Arch Pediatr Adolesc Med. 1995 Aug;149(8):930-1. Unique Identifier : AIDSLINE MED/95360161; Meyers A
Redox regulation of programmed cell death in lymphocytes.: Free Radic Res. 1995 May;22(5):389-97. Unique Identifier : AIDSLINE MED/95360176; Buttke TM; Sandstrom PA; Department of Microbiology & Immunology, East Carolina University; School of Medicine, Greenville, North Carolina 27858-4354, USA.; A redox imbalance caused by an over-production of prooxidants or a decrease in antioxidants seems to play a role in the programmed cell death that occurs in various developmental programs. Such a physiological function for oxidative stress is particularly applicable to the immune system, wherein individual lymphocytes
Increase in activated CD8+ cells in bronchoalveolar lavage fluid in patients with diffuse panbronchiolitis.: Am J Respir Crit Care Med. 1995 Aug;152(2):613-8. Unique Identifier : AIDSLINE MED/95360334; Mukae H; Kadota J; Kohno S; Kusano S; Morikawa T; Matsukura S; Hara K; Third Department of Internal Medicine, Miyazaki Medical College,; Japan.; To study the role of T cells in diffuse panbronchiolitis (DPB), we investigated T-cell subsets in bronchoalveolar lavage fluid (BALF) or 33 patients with DPB, nine patients with bronchiectasis, and 20 healthy volunteers. BALF from DPB patients contained a higher percentage of neutrophils than that from patients with b
Pulmonary function tests in HIV-infected patients without AIDS. Pulmonary Complications of HIV Infection Study Group.: Am J Respir Crit Care Med. 1995 Aug;152(2):738-45. Unique Identifier : AIDSLINE MED/95360355; Rosen MJ; Lou Y; Kvale PA; Rao AV; Jordan MC; Miller A; Glassroth J; Reichman LB; Wallace JM; Hopewell PC; Department of Medicine, Beth Israel Medical Center, New York, New; York 10003, USA.; To determine the prevalence, incidence, and types of lung diseases that occur in association with HIV infection, 1,353 subjects, including HIV-seropositive homosexual men, injection drug users, female sexual partners of HIV-positive men, and HIV-seronegative control subjects from the first two transmission categories
Radiographic abnormalities in tuberculosis and risk of coexisting human immunodeficiency virus infection. Results from Dar-es-Salaam, Tanzania, and scoring system.: Am J Respir Crit Care Med. 1995 Aug;152(2):786-93. Unique Identifier : AIDSLINE MED/95360362; Mlika-Cabanne N; Brauner M; Mugusi F; Grenier P; Daley C; Mbaga I; Larouze B; Murray JF; Institut National de la Sante et de la Recherche Medicale; (INSERM), Unite 13, Hopital Claude Bernard, Paris, France.; First, we evaluated the age profile and chest radiographic abnormalities in 146 patients from Dar-es-Salaam, Tanzania , with new-onset intrathoracic tuberculosis (pulmonary, pleural, or hilar/mediastinal adenopathy), to identify features that were associated with human immunodefic
Radiographic abnormalities in tuberculosis and risk of coexisting human immunodeficiency virus infection. Methods and preliminary results from Bujumbura, Burundi.: Am J Respir Crit Care Med. 1995 Aug;152(2):794-9. Unique Identifier : AIDSLINE MED/95360363; Mlika-Cabanne N; Brauner M; Kamanfu G; Grenier P; Nikoyagize E; Aubry P; Larouze B; Murray JF; Institut National de la Sante et de la Recherche Medicale; (INSERM), Unite 13, Hopital Claude Bernard, Paris, France.; We evaluated the age profile and chest radiographic abnormalities in 158 patients from Bujumbura, Burundi , with new-onset intrathoracic tuberculosis (pulmonary, pleural, or hilar/mediastinal adenopathy), to identify features that were associated with and would allow prediction of
Fungal infection in HIV-infected persons. American Thoracic Society.: Am J Respir Crit Care Med. 1995 Aug;152(2):816-22. Unique Identifier : AIDSLINE MED/95360368
Salmonella pyomyositis in patients with the human immunodeficiency virus.: Br J Rheumatol. 1995 Jun;34(6):568-71. Unique Identifier : AIDSLINE MED/95360422; Medina F; Fuentes M; Jara LJ; Barile L; Miranda JM; Fraga A; Rheumatic Diseases Unit, Hospital de Especialidades, Centro; Medico La Raza, Instituto Mexicano del Seguro Social, Mexico; City.; Pyomyositis is a common disease in the tropics, mostly due to Staphylococcus aureus. We report two patients infected with the human immunodeficiency virus (HIV) who presented with fever and unilateral limb swelling and in whom pyomyositis was diagnosed in quadriceps and gluteus major, respectively. Salmonella enteriti
The Edinburgh City Hospital cohort: analysis of enrollment, progression and mortality by baseline covariates.: QJM. 1995 Jul;88(7):479-91. Unique Identifier : AIDSLINE MED/95360506; Brettle RP; McNeil AJ; Gore SM; Bird AG; Leen CS; Richardson A; Regional Infectious Disease Unit, City Hospital, Edinburgh.; We describe baseline characteristics, enrollment, progression and mortality of the Edinburgh City Hospital HIV cohort. There were 431 men and 191 (31%) women; 439 (71%) infected via injection drug use (IDU); 92 (15%) via homosexual intercourse; 84 (13%) via heterosexual intercourse and 7 from blood products. Median an
Intravenous immune globulin for prevention of bacterial infections in pediatric AIDS patients.: Am J Health Syst Pharm. 1995 Apr 15;52(8):803-11. Unique Identifier : AIDSLINE MED/95360759; Crow ME; Campbell University, Department of Pharmacy Practice, Buies; Creek, NC 27506, USA.; The immunologic and clinical abnormalities associated with pediatric human immunodeficiency virus (HIV) infection are reviewed, the rationale for using intravenous immune globulin (IVIG) to prevent serious bacterial infections is described, and clinical experience with IVIG for this indication is summarized. Immunolog
Recommendation of treatment that would allow parole.: Am J Health Syst Pharm. 1995 Apr 15;52(8):829; discussion 829-34. Unique Identifier : AIDSLINE MED/95360762; Hsu I; DuChane J; Veatch RM; Clinical Education Programs, Medical Education Systems, Inc.,; Philadelphia, PA 19103-7415, USA.
Evaluation of a rapid microfiltration test for detection of HIV-1 antibody in serum.: Chung Hua I Hsueh Tsa Chih (Taipei). 1995 Jun;55(6):427-31. Unique Identifier : AIDSLINE MED/95360827; Wang SY; Lin TL; Chen HY; Horng CB; National Institute of Preventive Medicine, Department of Health,; Executive Yuan, Taipei, Taiwan, R.O.C.; BACKGROUND. Since the number of asymptomatic Human Immunodeficiency Virus Type 1 (HIV-1) infections has increased rapidly recently, to detect HIV-1 antibody rapidly becomes very critical when a quick mass survey is required or especially badly injured persons need blood transfusions immediately. This study evaluated s
Benefit of open lung biopsy in patients with respiratory failure.: Can J Surg. 1995 Aug;38(4):316-21. Unique Identifier : AIDSLINE MED/95360845; Lachapelle KJ; Morin JE; Division of Cardiovascular and Thoracic Surgery, Royal Victoria; Hospital, McGill University, Montreal, Que.; OBJECTIVE: To determine the benefit of open lung biopsy (OLB) in patients with respiratory failure in whom medical therapy is unsuccessful. DESIGN: A retrospective case series. SETTING: A tertiary care centre. PATIENTS: Thirty-one patients (20 men, 11 women, mean age 55 years) without the human immunodeficiency virus
Identification of a signal for rapid export of proteins from the nucleus.: Cell. 1995 Aug 11;82(3):463-73. Unique Identifier : AIDSLINE MED/95360990; Wen W; Meinkoth JL; Tsien RY; Taylor SS; Department of Chemistry and Biochemistry, Howard Hughes Medical; Institute, University of California, San Diego, La Jolla; 92093-0654, USA.; Active nuclear import of protein is controlled by nuclear localization signals (NLSs), but nuclear export is not understood well. Nuclear trafficking of the catalytic (C) subunit of cAMP-dependent protein kinase (cAPK) is critical for regulation of gene expression. The heat-stable inhibitor (PKl) of cAPK contains a nu
Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins.: Cell. 1995 Aug 11;82(3):485-94. Unique Identifier : AIDSLINE GENBANK/L42025; Bogerd HP; Fridell RA; Madore S; Cullen BR; Howard Hughes Medical Institute, Duke University Medical Center,; Durham, North Carolina 27710, USA.; HIV-1 Rev is the prototype of a class of retroviral regulatory proteins that induce the sequence-specific nuclear export of target RNAs. This function requires the Rev activation domain, which is believed to bind an essential cellular cofactor. We report the identification of a novel human gene product that binds to n
Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast.: Cell. 1995 Aug 11;82(3):495-506. Unique Identifier : AIDSLINE GENBANK/U30614; Stutz F; Neville M; Rosbash M; Howard Hughes Medical Institute, Brandeis University, Waltham,; Massachusetts 02254, USA.; The HIV-1 Rev protein increases the cytoplasmic levels of unspliced and singly spliced target transcripts in metazoan systems. Based on experiments that indicate a similar function of Rev in the yeast S. cerevisiae, we have identified a yeast protein that interacts with the effector domain of Rev. The protein, Rip1p,
Induction of human T cells that coexpress CD4 and CD8 by an immunomodulatory protein produced by Actinobacillus actinomycetemcomitans.: Cell Immunol. 1995 Aug;164(1):36-46. Unique Identifier : AIDSLINE MED/95361008; Shenker BJ; Vitale L; King C; Department of Pathology, University of Pennsylvania School of; Dental Medicine, Philadelphia 19104-6002, USA.; Actinobacillus actinomycetemcomitans, a gram-negative, capnophilic bacterium, is associated with several human diseases and is the suspected etiologic agent in certain forms of periodontal disease. We have previously shown that this organism produces an immunosuppressive factor (ISF) which is capable of inhibiting bot
Knowledge, attitude and beliefs amongst inhabitants of high density informal settlements with regard to sexuality and AIDS in Alexandra township.: Curationis. 1995 Jun;18(2):41-4. Unique Identifier : AIDSLINE MED/95361036; Ratsaka M; Hirschowitz R; OBJECTIVE: The main purpose of this study was to gain information on the knowledge that people living in squatter conditions have about AIDS, their attitude towards this disease and their sexual practices. METHOD: The study had two parts, in-depth interviews and a survey. The in-depth interviews were held with 68 male
[Doctor-patient--patient -doctor relationship: an ethical perspective]: Curationis. 1995 Jun;18(2):45-8. Unique Identifier : AIDSLINE MED/95361037; Lategan LO; In this article the author analyses the doctor-patient and patient-doctor relationship seen from two ethical viewpoints, namely the question of what is the meaning of privacy in the relationship between the doctor and his patient and whether the truth should always be told. The author comes to the conclusion that priv
T-cells and T-cell clones in rheumatic fever valvulitis. Getting to the heart of the matter? [editorial]: Circulation. 1995 Aug 1;92(3):281-2. Unique Identifier : AIDSLINE MED/95361113; Zabriskie JB
Sensitivity of osteoinductive activity of demineralized and defatted rat femur to temperature and duration of heating.: Clin Orthop. 1995 Jul;(316):267-75. Unique Identifier : AIDSLINE MED/95361409; Ito T; Sakano S; Sato K; Sugiura H; Iwata H; Murata Y; Seo H; Department of Orthopaedic Surgery, School of Medicine, Nagoya,; Japan.; For autogenous and allogeneic bone grafts, heat treatment has been thought to kill malignant cells and viruses such as human immunodeficiency virus. It is unclear whether heat treatment could preserve bone-inductive activity. Cortical bones from 6-week-old rat femurs were heated in a water bath at a temperature of 50
Attitudes and knowledge of Indian dental professionals about HIV infection and AIDS.: Community Dent Oral Epidemiol. 1995 Jun;23(3):187-8. Unique Identifier : AIDSLINE MED/95361473; Nair RG; Samaranayake LP; Bhat M; Anil S; Oral Biology Unit, Faculty of Dentistry, University of Hong Kong.
Tissue transglutaminase: a candidate effector element of physiological cell death.: Curr Top Microbiol Immunol. 1995;200:163-75. Unique Identifier : AIDSLINE MED/95361535; Piacentini M; Department of Biology, University of Rome Tor Vergata, Italy.
Chronic activation of the immune system in HIV infection: contribution to T cell apoptosis and V beta selective T cell anergy.: Curr Top Microbiol Immunol. 1995;200:177-93. Unique Identifier : AIDSLINE MED/95361536; Gougeon ML; Departement SIDA et Retrovirus, Institut Pasteur, Paris,; France.
Programmed cell death and AIDS pathogenesis: significance and potential mechanisms.: Curr Top Microbiol Immunol. 1995;200:195-211. Unique Identifier : AIDSLINE MED/95361537; Ameisen JC; Estaquier J; Idziorek T; De Bels F; Unite INSERM U 415 Pathogenese du sida et des infections a; tropisme immunitaire et nerveux, Institut Pasteur, Lille, France.
Programmed death of T cells in HIV infection: result of immune activation?: Curr Top Microbiol Immunol. 1995;200:213-21. Unique Identifier : AIDSLINE MED/95361538; Meyaard L; Miedema F; Department of Clinical Viro-Immunology, University of Amsterdam,; The Netherlands.
Botryomycosis in the acquired immunodeficiency syndrome.: Cutis. 1995 Mar;55(3):149-52. Unique Identifier : AIDSLINE MED/95361548; Ahdoot D; Rickman LS; Haghighi P; Heard WU; Department of Medicine, University of California Medical Center,; San Diego 92103, USA.; Botryomycosis is a rare bacterial infection that may mimic fungal disease both clinically and histologically. Cutaneous botryomycosis is uncommon and usually appears as plaques with superficial pustules and crusts. On microscopic examination lesions are characterized by the presence of granules that resemble the sulfu
Lupus-like eruption and human immunodeficiency virus infection.: Cutis. 1995 Mar;55(3):153-4. Unique Identifier : AIDSLINE MED/95361549; Werninghaus K; Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756,; USA.; Aberrant production of antibodies has been reported in some patients infected with human immunodeficiency virus. However, manifestations of autoimmune disease are rare. A case of a human immunodeficiency virus seropositive patient with a high titer of antinuclear antibodies and clinical manifestations of psoriasiform
Disseminated granuloma annulare in acquired immunodeficiency syndrome: case report and review of the literature.: Cutis. 1995 Mar;55(3):158-60. Unique Identifier : AIDSLINE MED/95361550; Calista D; Landi G; Department of Dermatology, Ospedale M. Bufalini, Cesena, Italy.; The authors report the case of a 27-year-old woman who presented with disseminated granuloma annulare in association with acquired immunodeficiency syndrome. The lesions were asymptomatic, tiny, erythematous or flesh-colored umbilicated papules on the neck, trunk, and flexor surface of the arms and knees that regresse
Disseminated histoplasmosis in a patient with acquired immunodeficiency syndrome.: Cutis. 1995 Mar;55(3):161-4. Unique Identifier : AIDSLINE MED/95361551; Cirillo-Hyland VA; Gross P; Bryn Mawr Hospital, Pennsylvania, USA.; No matter how typical a cutaneous eruption may be in a patient with the acquired immunodeficiency syndrome, early histologic evaluation is necessary if a delay in diagnosis and treatment is to be avoided. We report the case of a 33-year-old man with acquired immunodeficiency syndrome who was clinically misdiagnosed as
Papular mucinosis associated with acquired immunodeficiency syndrome.: Cutis. 1995 Mar;55(3):174-6. Unique Identifier : AIDSLINE MED/95361553; Gildersleeve RF; Kirk JF; Cooper PH; Greer KE; Department of Dermatology, University of Virginia Health Sciences; Center, Charlottesville 22908, USA.; Papular mucinosis, also known as lichen myxedematosus, is a rare, idiopathic disorder in which focal deposits of mucin accumulate in the dermis. It has been previously reported in two patients with human immunodeficiency virus infection; we describe a third such case and note the presence of a granuloma adjacent to th
Does cytomegalovirus predict a poor prognosis in Pneumocystis carinii pneumonia treated with corticosteroids? A note for caution.: Chest. 1995 Aug;108(2):411-4. Unique Identifier : AIDSLINE MED/95361580; Jensen AM; Lundgren JD; Benfield T; Nielsen TL; Vestbo J; Department of Infectious Diseases, Hvidovre Hospital, University; of Copenhagen, Denmark.; OBJECTIVE: To examine the importance of cytomegalovirus ( CMV ) in bronchoalveolar lavage (BAL) fluid of patients with HIV-associated Pneumocystis carinii pneumonia (PCP) treated with adjunctive corticosteroids (CS). DESIGN: An
Serum lactate dehydrogenase (LDH) in Pneumocystis carinii pneumonia, tuberculosis, and bacterial pneumonia.: Chest. 1995 Aug;108(2):415-8. Unique Identifier : AIDSLINE MED/95361581; Quist J; Hill AR; SUNY Health Science Center, Brooklyn, USA.; An increase in serum lactate dehydrogenase (LDH) activity is commonly taken to support the presumptive diagnosis of Pneumocystis carinii pneumonia (PCP), although the LDH level may also be increased in other lung infections and in a variety of extrapulmonary disorders. To assess its diagnostic value in patients with f
Pulmonary complications associated with illicit drug use. An update.: Chest. 1995 Aug;108(2):460-3. Unique Identifier : AIDSLINE MED/95361588; O'Donnell AE; Selig J; Aravamuthan M; Richardson MS; Department of Medicine, District of Columbia General Hospital,; Washington, DC, USA.; STUDY OBJECTIVE: In earlier years, nonopportunistic infectious pulmonary complications of illicit drug use were most common. We designed this study to update the pulmonary complications associated with illicit drug use in the 1990s. DESIGN: Concurrent and retrospective chart review. SETTING: Inner-city municipal hospi
Kerley B lines in AIDS.: Chest. 1995 Aug;108(2):561-2. Unique Identifier : AIDSLINE MED/95361603; Johnson F 3rd; Metersky ML; Pulmonary Division, University of Connecticut Health Center,; Farmington, USA.
Autogenous vaccine: the best therapy for perianal condyloma acuminata?: Dis Colon Rectum. 1995 Aug;38(8):838-41. Unique Identifier : AIDSLINE MED/95361683; Wiltz OH; Torregrosa M; Wiltz O; Department of Colon and Rectal Surgery, Hospital San Jorge, San; Juan, Puerto Rico.; PURPOSE: Treatment of perianal condyloma acuminata is frustrating because most treatment options are fraught with high recurrence rates and patient discomfort. We propose that surgical excision followed by vaccination with an autogenous condyloma acuminata vaccine is the most effective therapy available in primary and
Ocular manifestations of systemic disease.: Emerg Med Clin North Am. 1995 Aug;13(3):607-30. Unique Identifier : AIDSLINE MED/95361793; Rothenhaus TC; Polis MA; Department of Emergency Medicine, George Washington; University/Georgetown University Affiliated Residency,; Washington, DC, USA.; Systemic diseases can present with ocular manifestations to the emergency physician. Although most ocular findings serve to alert the physician to a possible ocular complication, many are different enough to aid the physician in making an obscure diagnosis. Knowledge of the characteristic ophthalmologic manifestations
[Chronic diarrhea: difficulties in determining the etiology. Diagnosis from irritable bowel syndrome to AIDS]: Fortschr Med. 1995 Jun 10;113(16):45-6. Unique Identifier : AIDSLINE MED/95362115; Blaeser-Kiel G
Human herpesvirus type 6 and cytomegalovirus in AIDS-associated Kaposi's sarcoma: no evidence for an etiological association.: Hum Pathol. 1995 Aug;26(8):914-9. Unique Identifier : AIDSLINE MED/95362232; Kempf W; Adams V; Pfaltz M; Briner J; Schmid M; Moos R; Hassam S; Department of Pathology, University of Zurich, Switzerland.; Epidemiological studies indicate that acquired immune deficiency syndrome (AIDS)-associated Kaposi s sarcoma (KS) may be caused by an infectious, preferentially sexually transmitted agent. Herpesviruses infections are common sexually transmitted diseases in homosexual men, who are also the main risk group for developi
Sexually transmitted diseases including HIV infection in women with Bartholin's gland abscesses.: Genitourin Med. 1995 Jun;71(3):155-7. Unique Identifier : AIDSLINE MED/95362268; Hoosen AA; Nteta C; Moodley J; Sturm AW; Department of Obstetrics and Gynaecology, Faculty of Medicine,; University of Natal, Durban, South Africa.; OBJECTIVES--The aim of this study was to establish the prevalence of sexually transmitted infections including human immunodeficiency virus (HIV) infection in women with Bartholin s gland abscess. SETTING--Gynaecology Clinic of King Edward VIII Hospital, a large urban, referral hospital for the province of Kwa-Zulu Na
Disseminated cryptococcal infection despite treatment for cryptococcal meningitis [clinical conference]: Genitourin Med. 1995 Jun;71(3):187-92. Unique Identifier : AIDSLINE MED/95362275; Miller RF; Lucas SB; De Cock KM; Hay RJ; Department of Medicine, University College, London Medical; School, UK.
Asthma in an AIDS patient with Norwegian scabies induced by bathing [letter]: Genitourin Med. 1995 Jun;71(3):200. Unique Identifier : AIDSLINE MED/95362284; Corbett EL; Crossley I; De Cock KM
STD/HIV control in Malawi [letter; comment]: Genitourin Med. 1995 Jun;71(3):202. Unique Identifier : AIDSLINE MED/95362288; Taylor-Robinson D; Ballard RC; Thomas BJ; Renton A
In vitro infection of human epidermal Langerhans' cells with HIV-1.: Immunology. 1995 May;85(1):94-8. Unique Identifier : AIDSLINE MED/95362312; Ramazzotti E; Marconi A; Re MC; Girolomoni G; Cenacchi G; Vignoli M; Zambruno G; Furlini G; La Placa M; Giannetti A; Institute of Microbiology, University of Bologna, Italy.; Epidermal Langerhans cells (LC) from human immunodeficiency virus type-1 (HIV-1)-infected patients harbour HIV-1 proviral DNA and RNA. In the present study, we investigated whether LC from epidermis of normal, HIV-seronegative subjects could be infected in vitro with HIV-1. Epidermal cells (EC) spontaneously detached
Attitude of French general practitioners to the public health surveillance of communicable diseases.: Int J Epidemiol. 1995 Apr;24(2):435-40. Unique Identifier : AIDSLINE MED/95362400; Chauvin P; Valleron AJ; Unite de Recherches Biomathematiques et Biostatistiques de; l'INSERM (U263), Faculte Saint Antoine, Paris, France.; BACKGROUND. The attitude of general practitioners (GPs) to public health surveillance is not well documented, even though they furnish essential information, in particular for sentinel surveillance among the general population. METHODS. The attitude of 560 French GPs to the surveillance of 17 communicable diseases was
Estimation of the size of the HIV/AIDS epidemic due to blood transfusion in France.: Int J Epidemiol. 1995 Apr;24(2):441-5. Unique Identifier : AIDSLINE MED/95362401; Le Pont F; Costagliola D; Massari V; Valleron AJ; INSERM U263, Universite Pierre et Marie Curie, Faculte de; Medecine St Antoine, Paris, France.; BACKGROUND. This study presents estimates of the number of individuals contaminated by human immunodeficiency virus (HIV) via a blood transfusion received in France before the end of 1991 and those who have developed or will develop AIDS. METHODS. The computer simulation model take
Model-based estimates of the risk of human immunodeficiency virus and hepatitis B virus transmission through unsafe injections.: Int J Epidemiol. 1995 Apr;24(2):446-52. Unique Identifier : AIDSLINE MED/95362402; Aylward B; Kane M; McNair-Scott R; Hu DH; Global Programme for Vaccines and Immunization, World Health; Organization, Geneva, Switzerland.; BACKGROUND. Patient-to-patient transmission through contaminated medical equipment may be the principal route of nosocomial blood-borne infections globally. Quantifying cross infection risks could facilitate efforts to ensure safe injections in developing countries. METHOD. A mathematical model was developed to evalua
Analysis of care of HIV positive patients: hospital and general practice components.: Ir Med J. 1995 May-Jun;88(3):98-100. Unique Identifier : AIDSLINE MED/95362496; Bradley F; Bury G; O'Kelly F; Shannon W; Hickey A; Mulcahy F; HIV Primary Care Research Unit, Coombe Healthcare Centre, Dublin.; Fifty-seven HIV positive adults (mostly injecting drug users) attending two inner city Dublin general practices were followed for one year to identify the general practice and hospital components of their care. Many patients had advanced disease; during the year 10/57 (17.5%) died. The group made a median of seven vis
Nursing research in HIV/AIDS home care, Part 2: Results and implications.: Home Healthc Nurse. 1995 Jul-Aug;13(4):9-13. Unique Identifier : AIDSLINE MED/95362565; Ungvarski PJ; Hurley PM; This study categorized the problems of clients with human immunodeficiency syndrome/acquired immune deficiency syndrome (HIV/AIDS), identified on admission to home care, into nursing diagnoses. The study followed a descriptive retrospective record review of adult men and women (n = 244) admitted to a certified home he
An approach to antiretroviral treatment of HIV disease. Combined antiretroviral therapy: the emerging role.: Hosp Pract (Off Ed). 1995 Aug;30 Suppl 1:23-31. Unique Identifier : AIDSLINE MED/95362765; Deeks S; Volberding P; University of California, San Francisco, USA.; Early, aggressive antiretroviral therapy may soon be considered state of the art. A new generation of antiretroviral agents will soon be available, many of them well tolerated and effective, particularly when used in combination with zidovudine and other nucleoside analogues. Combined antiretroviral therapy represents
An approach to antiretroviral treatment of HIV disease. The situation: an overview.: Hosp Pract (Off Ed). 1995 Aug;30 Suppl 1:3-4. Unique Identifier : AIDSLINE MED/95362766; Saag MS; University of Alabama at Birmingham, USA.
An approach to antiretroviral treatment of HIV disease. Individualized therapy: the role of viral-burden measures.: Hosp Pract (Off Ed). 1995 Aug;30 Suppl 1:41-50. Unique Identifier : AIDSLINE MED/95362768; Thompson MA; AIDS Research Consortium of Atlanta, USA.; Surrogate markers such as the CD4 lymphocyte count and viral p24 antigen level have now been joined by assays of HIV nucleic acid in patients plasma as a measure of viral burden. The findings are already assisting in the development and clinical testing of antiretroviral agents. They also may facilitate therapeutic d
An approach to antiretroviral treatment of HIV disease. Nucleoside monotherapy.: Hosp Pract (Off Ed). 1995 Aug;30 Suppl 1:5-22. Unique Identifier : AIDSLINE MED/95362769; Gunnarsson G; Hammer SM; Department of Medicine, New England Deaconess Hospital, Harvard; Medical School, Boston, USA.; Despite hopes for attack of multiple viral targets, the licensed agents now in use are all of one type: the nucleoside analogue reverse transcriptase inhibitors, of which four, including zidovudine, are available, with a fifth likely to follow. Clinicians and patients are still struggling to learn how best to employ t
A macaque adherent cell line that expresses human CD4 is susceptible to SIV: utility for assessing neutralizing antibody.: J Virol Methods. 1995 May;53(1):139-48. Unique Identifier : AIDSLINE MED/95362784; Goldstein S; Hague B; Montefiori D; Hirsch VM; Immunodeficiency Viruses Section, LID, NIAID, NIH Twinbrook; Facility, Rockville, MD 20852, USA.; A macaque CD4 + adherent cell line was generated by stable expression of the human CD4 gene in a rhesus macaque mammary tumor cell line, CMMT. The resulting cell line CMMT/CD4 expressed surface CD4 and was sensitive to infection by a wide range of isolates of simian immunodeficiency virus (SIV) of different subgroups,
Assay of HIV-1 protease activity by use of crude preparations of enzyme and biotinylated substrate.: J Virol Methods. 1995 May;53(1):63-73. Unique Identifier : AIDSLINE MED/95362791; Yu SL; Wang N; Liou CY; Syu WJ; Graduate Institute of Microbiology and Immunology, National; Yang-Ming University, Taipei, Taiwan, ROC.; An enzyme immunoassay was developed for monitoring protease reactions of human immunodeficiency virus (HIV). The protease and its substrate, the gag precursor, were generated separately in Escherichia coli. The HIV-1 protease was generated with a glutathione-S-transferase expression system and the gag substrate, named
Identification of an idiotypic peptide recognized by autoantibodies in human immunodeficiency virus-1-infected individuals.: J Clin Invest. 1995 Aug;96(2):775-80. Unique Identifier : AIDSLINE MED/95362838; Wang QL; Wang HT; Blalock E; Muller S; Kohler H; Markey Cancer Center, University of Kentucky Medical Center,; Lexington 40536-0096, USA.; Antibodies against HIV-1 proteins in HIV-1-infected individuals share a cross-reactive idiotype defined by the monoclonal antiidiotypic antibody 1F7 (5). Using a computer algorithm based on the molecular recognition theory, regions of inverse hydropathy between the variable sequence of 1F7 and human monoclonal anti-HI
ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids.: J Clin Invest. 1995 Aug;96(2):867-76. Unique Identifier : AIDSLINE MED/95362849; Pinto LA; Sullivan J; Berzofsky JA; Clerici M; Kessler HA; Landay AL; Shearer GM; Experimental Immunology Branche, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892, USA.; Identification of the components of protective immunity are crucial for the development of effective prophylactic and therapeutic vaccine strategies. Analysis of HIV-specific responses in exposed but uninfected individuals might thus provide a unique resource to elucidate the components and correlates of protective im
Recognition of clonogenic leukemic cells, remission bone marrow and HLA-identical donor bone marrow by CD8+ or CD4+ minor histocompatibility antigen-specific cytotoxic T lymphocytes.: J Clin Invest. 1995 Aug;96(2):877-83. Unique Identifier : AIDSLINE MED/95362850; Faber LM; van der Hoeven J; Goulmy E; Hooftman-den Otter AL; van Luxemburg-Heijs SA; Willemze R; Falkenburg JH; Department of Hematology, University Medical Center, Leiden, The; Netherlands.; We investigated whether minor histocompatibility (mH) antigen-specific cytotoxic T lymphocytes (CTL) can discriminate between leukemic hematopoietic progenitor cells (leukemic-HPC) from AML or CML patients, the HPC from their remission bone marrow (remission-HPC), and normal HPC from their HLA-identical sibling bone m
Hearing impairment in older adults: new concepts.: J Am Geriatr Soc. 1995 Aug;43(8):928-35. Unique Identifier : AIDSLINE MED/95362983; Jerger J; Chmiel R; Wilson N; Luchi R; Department of Otorhinolaryngology and Communicative Sciences,; Baylor College of Medicine, Houston, Texas, USA.; OBJECTIVE: To review present information about the epidemiology, etiologies, pathogenesis, evaluation, and quality of life aspects of hearing loss and to present an approach to rehabilitation for hearing loss in older adults. DESIGN: A survey of recent findings on the problem of hearing loss in older adults, efficacy
Sociodemographic characteristics of HIV infection in northern India.: J Commun Dis. 1995 Mar;27(1):1-9. Unique Identifier : AIDSLINE MED/95363027; Giri TK; Wali JP; Meena HS; Pande I; Uppal S; Kailash S; Department of Medicine, All India Institute of Medical Sciences,; New Delhi.; 134 patients testing positive for HIV antibody during the period 1986-1993 were included in the present study. An in-depth analysis of the subjects revealed that the adult males seemed to have the highest propensity for HIV infection in this part of the country. Marital status had no bearing on incidence and route of
HIV infection among the high risk groups of Upper Assam.: J Commun Dis. 1995 Mar;27(1):15-8. Unique Identifier : AIDSLINE MED/95363029; Hazarika A; Chelleng PK; Satyanarayana K; Mahanta J; Regional Medical Research Centre, N.E. Region (ICMR), Dibrugarh.; Serum samples of 9350 individuals belonging to different high risk groups were tested for HIV Infection by ELISA and western blot technique. 9 samples were found to be positive. Two of them belonged to indigenous people of Assam and the infection was transfusion/transplant associated and acquired outside the state dur
Occupational risk of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus infections among funeral service practitioners in Maryland [see comments]: Infect Control Hosp Epidemiol. 1995 Apr;16(4):194-7. Unique Identifier : AIDSLINE MED/95363049; Gershon RR; Vlahov D; Farzadegan H; Alter MJ; Department of Environmental Health Science, Johns Hopkins; University School of Hygiene and Public Health, Baltimore; 21205-2179, USA.; OBJECTIVE: To estimate the risk of exposure and infection with bloodborne pathogens, a seroepidemiologic survey was conducted among funeral service practitioners (FSPs) in Maryland. METHOD: Of 262 members of the Maryland State Funeral Directors Association, 130 (49%) volunteered to participate in the study. In additio
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.: J Immunol. 1995 Aug 1;155(3):1151-64. Unique Identifier : AIDSLINE MED/95363080; Sakaguchi S; Sakaguchi N; Asano M; Itoh M; Toda M; Precursory Research for Embryonic Science and Technology; (PRESTO), Research and Development Corporation of Japan (JRDC),; Tsukuba Life Science Center.; Approximately 10% of peripheral CD4+ cells and less than 1% of CD8+ cells in normal unimmunized adult mice express the IL-2 receptor alpha-chain (CD25) molecules. When CD4+ cell suspensions prepared from BALB/c nu/+ mice lymph nodes and spleens were depleted of CD25+ c
Small amounts of exogenous IL-4 increase the severity of encephalitis induced in mice by the intranasal infection of herpes simplex virus type 1.: J Immunol. 1995 Aug 1;155(3):1326-33. Unique Identifier : AIDSLINE MED/95363097; Ikemoto K; Pollard RB; Fukumoto T; Morimatsu M; Suzuki F; Department of Neurology, Yamaguchi University School of Medicine,; Japan.; The effect of murine rIL-4 on the development of herpesvirus encephalitis (HSE) in mice infected intranasally with herpes simplex virus type 1 (HSV-1) was investigated. The mortality rates of mice infected with a 0.5 LD50 dose of HSV-1 were greatly increased after the administration of rIL-4 at doses ranging from 0.01
TGF-beta is important in determining the in vivo patterns of susceptibility or resistance in mice infected with Candida albicans.: J Immunol. 1995 Aug 1;155(3):1349-60. Unique Identifier : AIDSLINE MED/95363100; Spaccapelo R; Romani L; Tonnetti L; Cenci E; Mencacci A; Del Sero G; Tognellini R; Reed SG; Puccetti P; Bistoni F; Department of Experimental Medicine and Biochemical Sciences,; University of Perugia, Italy.; Resistance and susceptibility of mice to systemic infection with the fungus Candida albicans are associated with the preferential expansion of Th1 and Th2 cells, respectively. In this study, endogenous production of TGF-beta was found to be increased soon after infection of healer mice with a live vaccine strain of th
Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts.: J Immunol. 1995 Aug 1;155(3):1393-403. Unique Identifier : AIDSLINE MED/95363104; Zitvogel L; Tahara H; Robbins PD; Storkus WJ; Clarke MR; Nalesnik MA; Lotze MT; Department of Surgery, University of Pittsburgh Medical Center,; PA 15261, USA.; IL-12 is a heterodimeric cytokine produced by macrophages, mitogen stimulated- or EBV infected-B lymphocytes, keratinocytes, and probably dendritic cells, with important immunoregulatory functions in vitro and in vivo. It directly stimulates activated NK and T cells to produce high levels of IFN-gamma, enhances their
HIV infection suppresses type 1 lymphokine and IL-12 responses to Toxoplasma gondii but fails to inhibit the synthesis of other parasite-induced monokines.: J Immunol. 1995 Aug 1;155(3):1565-74. Unique Identifier : AIDSLINE MED/95363122; Gazzinelli RT; Bala S; Stevens R; Baseler M; Wahl L; Kovacs J; Sher A; Immunobiology Section, CCM/CC, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892, USA.; Individuals infected with Toxoplasma gondii normally develop resistance to the parasite, resulting in an asymptomatic chronic infection. In AIDS patients, this resistance is lost leading to reactivation of infection and development of encephalitis. To characterize the cytokine response of T. gondii-infected individual
Autoimmunity induction by human T cell leukemia virus type 1 in transgenic mice that develop chronic inflammatory arthropathy resembling rheumatoid arthritis in humans.: J Immunol. 1995 Aug 1;155(3):1588-98. Unique Identifier : AIDSLINE MED/95363124; Iwakura Y; Saijo S; Kioka Y; Nakayama-Yamada J; Itagaki K; Tosu M; Asano M; Kanai Y; Kakimoto K; Laboratory Animal Research Center, University of Tokyo, Japan.; We recently reported on an inflammatory arthropathy resembling rheumatoid arthritis that develops in high incidence among transgenic mice that carry the env-pX region of the human T cell leukemia virus type 1 genome. In an effort to elucidate the pathogenesis of this disease, we found that genes for inflammatory cytok
Lysosome-associated membrane protein-1-mediated targeting of the HIV-1 envelope protein to an endosomal/lysosomal compartment enhances its presentation to MHC class II-restricted T cells.: J Immunol. 1995 Aug 15;155(4):1818-28. Unique Identifier : AIDSLINE MED/95363149; Rowell JF; Ruff AL; Guarnieri FG; Staveley-O'Carroll K; Lin X; Tang J; August JT; Siliciano RF; Department of Medicine, Johns Hopkins University School of; Medicine, Baltimore, MD 21205, USA.; A subset of endogenously synthesized Ags can be processed for class II-restricted presentation, probably through multiple mechanisms. Processing of exogenous Ags for class II-restricted presentation appears to occur in unique endosomal processing compartments with lysosomal characteristics including the presence of th
Endogenously produced IL-12 is required for the induction of protective T cells during Mycobacterium avium infections in mice.: J Immunol. 1995 Aug 15;155(4):2013-9. Unique Identifier : AIDSLINE MED/95363168; Castro AG; Silva RA; Appelberg R; Center for Experimental Cytology, University of Porto, Portugal.; Immunity to Mycobacterium avium depends on the induction of protective CD4+ T cells. In mice, M. avium induces a Th1 response leading to protective immunity dependent on IFN-gamma and TNF. In this study, we analyzed whether endogenously produced IL-12 was involved in the generation of such protective T cells. We found
T cell receptor V beta complementarity-determining region 1 peptide administration moderates immune dysfunction and cytokine dysregulation induced by murine retrovirus infection.: J Immunol. 1995 Aug 15;155(4):2282-91. Unique Identifier : AIDSLINE MED/95363196; Watson RR; Wang JY; Dehghanpisheh K; Huang DS; Wood S; Ardestani SK; Liang B; Marchalonis JJ; Department of Family and Community Medicine, University of; Arizona College of Medicine, Tucson 85724, USA.; Murine AIDS, induced by LP-BM5 murine leukemia retrovirus infection, causes a progressive and profound immunodeficiency in female C57B1/6 mice. Previously, we reported that autoantibodies were elevated during the initiation phases of this murine retrovirus infection and bound peptide determinants corresponding to CDR1
Cerebral mass lesions due to cytomegalovirus in patients with AIDS: report of two cases.: J Infect. 1995 Mar;30(2):147-51. Unique Identifier : AIDSLINE MED/95363204; Dyer JR; French MA; Mallal SA; Department of Clinical Immunology, Royal Perth Hospital, Western; Australia.; Cytomegalovirus ( CMV ) is an increasingly important opportunistic pathogen in patients with HIV infection and advanced immune deficiency. Neurological complications due to CMV cause significant morbidity but may be treatable with specific anti-viral therapy: cere
Scedosporium prolificans, a multi-resistant fungus, from a U.K. AIDS patient.: J Infect. 1995 Mar;30(2):153-5. Unique Identifier : AIDSLINE MED/95363205; Hopwood V; Evans EG; Matthews J; Denning DW; Department of Microbiology, University of Leeds, U.K.; We report the first isolation of Scedosporium prolificans (inflatum) in the U.K. The patient, with advanced AIDS and neutropenia, had respiratory tract colonisation over many months without invasive disease despite neutropenia, while on itraconazole therapy. The organism was resistant in vitro to all licensed systemic
Kawasaki-like syndrome in an HIV positive adult.: J Infect. 1995 Mar;30(2):165-6. Unique Identifier : AIDSLINE MED/95363208; Yoganathan K; Goodman F; Pozniak A; Department of Genitourinary Medicine, Singleton Hospital, Sketty,; Swansea, U.K.
Epitope mapping of the V3 domain of feline immunodeficiency virus envelope glycoprotein by monoclonal antibodies.: J Gen Virol. 1995 Aug;76 ( Pt 8):1893-9. Unique Identifier : AIDSLINE MED/95363408; Lombardi S; Massi C; Tozzini F; Zaccaro L; Bazzichi A; Bandecchi P; La Rosa C; Bendinelli M; Garzelli C; Department of Biomedicine, University of Pisa, Italy.; A panel of six IgG monoclonal antibodies (MAbs) was produced by immunizing mice with a 22 amino acid synthetic peptide, designated V3.3, of the third variable region of feline immunodeficiency virus (FIV) envelope glycoprotein. This peptide is known to induce neutralizing antibodies in cats. In ELISA all MAbs reacted
Impact of natural sequence variation in the V2 region of the envelope protein of human immunodeficiency virus type 1 on syncytium induction: a mutational analysis.: J Gen Virol. 1995 Aug;76 ( Pt 8):1901-7. Unique Identifier : AIDSLINE MED/95363409; Andeweg AC; Boers PH; Osterhaus AD; Bosch ML; Laboratory of Immunobiology, National Institute of Public Health; and Environmental Protection, Bilthoven, The Netherlands.; Several studies have demonstrated a functional role for the V1-V2 region of the human immunodeficiency virus type 1 (HIV-1) envelope surface glycoprotein gp120 in the membrane fusion processes underlying viral entry and syncytium induction. In a study with chimeric primary envelope genes, we have previously demonstrat
Cytotoxic T cell response to Mengo virus in mice: effector cell phenotype and target proteins.: J Gen Virol. 1995 Aug;76 ( Pt 8):1999-2007. Unique Identifier : AIDSLINE MED/95363419; Escriou N; Leclerc C; Gerbard S; Giraud M; van der Werf S; Unite de Virologie Moleculaire, URA CNRS#1966, Institut; Pasteur, Paris, France.; The Mengo virus specific cytotoxic T lymphocyte (CTL) response was investigated after intraperitoneal infection of mice with the attenuated Mengo virus strain vMC24. A high level of CTL activity was detected in spleen cell cultures obtained from infected C3H/HeJ (H-2k) or C57BL/6 (H-2b) mice after a secondary in vitro
Persistent B19 parvovirus infections in haemophilic HIV-1 infected patients.: J Med Virol. 1995 Jun;46(2):103-8. Unique Identifier : AIDSLINE MED/95363434; Musiani M; Zerbini M; Gentilomi G; Rodorigo G; De Rosa V; Gibellini D; Venturoli S; Gallinella G; Institute of Microbiology, University of Bologna, Italy.; B19 infection can be acquired by transmission with blood factors in patients with congenital bleeding disorders, requiring clotting factor concentrates. In immunodeficient patients, the failure of immunity to clear B19 virus may produce persistent infections. The presence of B19 DNA in blood samples from seven haemoph
Peripheral lymphocytes of clinically non-progressor patients harbor inactive and uninducible HIV proviruses.: J Med Virol. 1995 Jun;46(2):116-21. Unique Identifier : AIDSLINE MED/95363436; Garbuglia AR; Salvi R; Di Caro A; Montella F; Di Sora F; Recchia O; Delfini C; Benedetto A; Center of Virology, S. Camillo Hospital, Rome, Italy.; The HIV viral burden and RNA expression in a selected group of infected, clinically non-progressor patients were investigated. Five fast-progressor patients and 10 AIDS cases were included as controls. The HIV viral load was investigated by semiquantitative polymerase chain reaction (PCR) in adherent macrophages and i
Hepatitis E virus infection in hemophiliacs.: J Med Virol. 1995 Jun;46(2):153-6. Unique Identifier : AIDSLINE MED/95363443; Barzilai A; Schulman S; Karetnyi YV; Favorov MO; Levin E; Mendelson E; Weiss P; Fields HA; Varon D; Martinowitz U; National Hemophilia Center, Chaim Sheba Medical Center, Tel; Hashomer, Israel.; Israel is endemic for hepatitis E virus (HEV), the causative agent of enteric non-A, non-B hepatitis. Transmission is via the feco-oral route but the possibility of transmission through blood transfusion has been raised. This question was addressed by examining sera from 188 hemoph
Phase I/II study of intermittent all-trans-retinoic acid, alone and in combination with interferon alfa-2a, in patients with epidemic Kaposi's sarcoma.: J Clin Oncol. 1995 Aug;13(8):1966-74. Unique Identifier : AIDSLINE MED/95363479; Bailey J; Pluda JM; Foli A; Saville MW; Bauza S; Adamson PC; Murphy RF; Cohen RB; Broder S; Yarchoan R; Medicine Branch, National Cancer Institute, National Institutes; of Health, Bethesda, MD 20892, USA.; PURPOSE: A phase I/II study of oral all-trans-retinoic acid (ATRA; tretinoin), administered every other week alone and then in combination with interferon (IFN) alfa-2a, was undertaken to evaluate the activity, toxicity, and pharmacokinetics of this regimen in patients with human immunodeficiency virus (HIV)-associate
Nursing ethics: understanding the moral life.: J N Y State Nurses Assoc. 1995 Mar;26(1):16-7. Unique Identifier : AIDSLINE MED/95363530; Scanlon C
Psychiatric nursing: trends for clinicians.: J N Y State Nurses Assoc. 1995 Mar;26(1):42-3. Unique Identifier : AIDSLINE MED/95363542; Sills GM
HIV/AIDS: lessons learned from an epidemic.: J N Y State Nurses Assoc. 1995 Mar;26(1):51-3. Unique Identifier : AIDSLINE MED/95363546; Ungvarski PJ
Effect of hepatitis C genotype on mother-to-infant transmission of virus.: J Pediatr. 1995 Aug;127(2):278-80. Unique Identifier : AIDSLINE MED/95363604; Zuccotti GV; Ribero ML; Giovannini M; Fasola M; Riva E; Portera G; Biasucci G; Decarlis S; Profeta ML; Tagger A; Pediatric Department, University of Milan, Italy.; We evaluated vertical transmission of hepatitis C virus (HCV) in 37 pregnant women, 20 of whom also had human immunodeficiency virus (HIV) antibody. The HCV subtypes 1a and 3a were prevalent among pregnant women with HIV infection. Infection with HCV was transmitted from 30.7% of the 13 mothers with HCV ribonucleic ac
Oropharyngeal candidiasis in immunocompromised children: a randomized, multicenter study of orally administered fluconazole suspension versus nystatin. The Multicenter Fluconazole Study Group.: J Pediatr. 1995 Aug;127(2):322-8. Unique Identifier : AIDSLINE MED/95363615; Flynn PM; Cunningham CK; Kerkering T; San Jorge AR; Peters VB; Pitel PA; Harris J; Gilbert G; Castagnaro L; Robinson P; Department of Infectious Diseases, St. Jude Children's Research; Hospital, Memphis, TN 38105-2794, USA.; OBJECTIVE: To compare the efficacy, safety, and tolerance of fluconazole suspension versus nystatin in the treatment of oropharyngeal thrush in immunocompromised children. DESIGN: Multicenter, randomized, observer-masked trial. SETTING: Thirty-two centers participated, includin
Cold urticaria, raised IgE and HIV infection.: J R Soc Med. 1995 May;88(5):294P-295P. Unique Identifier : AIDSLINE MED/95363788; Yu RC; Evans B; Cream JJ; Department of Dermatology, Charing Cross and Westminster Medical; School, London, UK.; We present a patient with cold urticaria as an unusual and late cutaneous manifestation of acquired immunodeficiency syndrome. The severe CD4 cell depletion and markedly elevated serum IgE levels in our patient provide some insights into certain aspects of immune regulatory mechanisms.
Synthesis and antiviral activity of 6-benzyl analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents.: J Med Chem. 1995 Jul 21;38(15):2860-5. Unique Identifier : AIDSLINE MED/95363806; Tanaka H; Takashima H; Ubasawa M; Sekiya K; Inouye N; Baba M; Shigeta S; Walker RT; De Clercq E; Miyasaka T; School of Pharmaceutical Science, Showa University, Tokyo, Japan.; Several 6-benzyl analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (1; HEPT) were synthesized and evaluated for their anti-HIV-1 activity. LDA (lithium diisopropylamide) lithiation of 5-ethyluracil derivatives 7 and 8 and subsequent reaction with an aryl aldehyde gave 6-(arylhydroxymethyl)-5-ethyluracil der
Synthetic chemical diversity: solid phase synthesis of libraries of C2 symmetric inhibitors of HIV protease containing diamino diol and diamino alcohol cores.: J Med Chem. 1995 Aug 4;38(16):2995-3002. Unique Identifier : AIDSLINE MED/95363822; Wang GT; Li S; Wideburg N; Krafft GA; Kempf DJ; Pharmaceutical Product Division, Abbott Laboratories, Abbott; Park, Illinois 60064, USA.; Solid phase synthesis of non-oligomeric organic compounds has been pursued for high-efficiency generation of large numbers of structurally diverse compounds for drug screening. Known as chemical diversity libraries or combinatorial libraries (when the synthesis is carried out in a combinatorial fashion), these compoun
Pattern of adult malignancies in Zambia (1980-1989) in light of the human immunodeficiency virus type 1 epidemic.: J Trop Med Hyg. 1995 Aug;98(4):281-4. Unique Identifier : AIDSLINE MED/95363890; Patil P; Elem B; Zumla A; Department of Pathology, University Teaching Hospital, Lusaka,; Zambia.; This study analysed histopathological and haematology records of 7836 neoplasms seen during the period 1980-1989 at the University Teaching Hospital, Lusaka, Zambia . The crude incidence rate of each malignancy per 100,000 adults per year was calculated and the patterns of malignanc
Intestinal parasites in HIV-seropositive Zambian children with diarrhoea.: J Trop Pediatr. 1995 Jun;41(3):149-52. Unique Identifier : AIDSLINE MED/95363896; Chintu C; Luo C; Baboo S; Khumalo-Ngwenya B; Mathewson J; DuPont HL; Zumla A; Department of Paediatrics & Child Health, University Teaching; Hospital, Lusaka, Zambia.; We undertook a study over a period of 9 months to define the frequency of parasitic infections in hospitalized children with diarrhoea between the ages of 15 months and 5 years. Every alternate day, mothers of all children admitted with diarrhoea between 09.00 hours and 12.00 hours to one of the wards of the Departmen
Gallbladder wall mass on sonography representing large-cell non-Hodgkin's lymphoma in an AIDS patient.: J Ultrasound Med. 1994 Jan;13(1):67-8. Unique Identifier : AIDSLINE MED/95363922; O'Boyle MK; Department of Radiology, Veterans Affairs Medical Center, San; Diego, California 92161, USA.
A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells.: J Virol. 1995 Sep;69(9):5217-27. Unique Identifier : AIDSLINE MED/95363926; LaBranche CC; Sauter MM; Haggarty BS; Vance PJ; Romano J; Hart TK; Bugelski PJ; Marsh M; Hoxie JA; Hematology-Oncology Division, Hospital of the University of; Pennsylvania, Philadelphia 19104, USA.; We have described a virus termed CP-MAC, derived from the BK28 molecular clone of simian immunodeficiency virus, that was remarkable for its ability to infect Sup-T1 cells with rapid kinetics, cell fusion, and CD4 down-modulation (C. C. LaBranche, M. M. Sauter, B. S. Haggarty, P. J. Vance, J. Romano, T. K. Hart, P. J.
In vitro selection and characterization of human immunodeficiency virus type 1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease.: J Virol. 1995 Sep;69(9):5228-35. Unique Identifier : AIDSLINE MED/95363927; Partaledis JA; Yamaguchi K; Tisdale M; Blair EE; Falcione C; Maschera B; Myers RE; Pazhanisamy S; Futer O; Cullinan AB; et al; Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts; 02139-4211, USA.; Human immunodeficiency virus type 1 (HIV-1) variants with reduced sensitivity to the hydroxyethylamino sulfonamide protease inhibitors VB-11,328 and VX-478 have been selected in vitro by two independent serial passage protocols with HIV-1 in CEM-SS and MT-4 cell lin
Tropism of varicella-zoster virus for human CD4+ and CD8+ T lymphocytes and epidermal cells in SCID-hu mice.: J Virol. 1995 Sep;69(9):5236-42. Unique Identifier : AIDSLINE MED/95363928; Moffat JF; Stein MD; Kaneshima H; Arvin AM; Department of Pediatrics, Stanford University Medical School,; California 94305, USA.; To investigate the cell tropism and pathogenicity of varicella-zoster virus (VZV) strains, we analyzed VZV replication by using SCID-hu mice that carry human fetal thymus/liver implants under the kidney capsule or as subcutaneous fetal skin implants. MRC-5 cells infected with wild-type VZV or the Oka strain, used in t
C/EBP proteins activate transcription from the human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes.: J Virol. 1995 Sep;69(9):5337-44. Unique Identifier : AIDSLINE MED/95363941; Henderson AJ; Zou X; Calame KL; Department of Microbiology, College of Physicians and Surgeons,; Columbia University, New York, New York 10032, USA.; Three binding sites for C/EBP proteins are found in the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) (V. M. Tesmer, A. Rajadhyaksha, J. Babin, and M. Bina, Proc. Natl. Acad. Sci. USA 90:7298-7302, 1993). We have determined the functional role of C/EBP proteins and C/EBP sites in regulating tr
Analysis of resistance to human immunodeficiency virus type 1 protease inhibitors by using matched bacterial expression and proviral infection vectors.: J Virol. 1995 Sep;69(9):5431-6. Unique Identifier : AIDSLINE MED/95363952; Maschera B; Furfine E; Blair ED; Gene Targets Group, Wellcome Research Laboratories, Beckenham,; United Kingdom.; There are already reports, from clinical trials with human immunodeficiency virus type 1 protease inhibitors , of the emergence of drug-resistant mutants which have one or more point mutations in their protease genes. To examine roles of individual and multiple amino
The caprine arthritis encephalitis virus tat gene is dispensable for efficient viral replication in vitro and in vivo.: J Virol. 1995 Sep;69(9):5445-54. Unique Identifier : AIDSLINE MED/95363954; Harmache A; Vitu C; Russo P; Bouyac M; Hieblot C; Peveri P; Vigne R; Suzan M; Institut National de la Sante et de la Recherche Medicale,; U372, Marseille, France.; Caprine arthritis encephalitis virus (CAEV) is a lentivirus closely related to visna virus and more distantly to other lentiviruses, such as human immunodeficiency virus. The genomes of visna virus and CAEV contain a tat gene encoding a protein able to weakly transactivate its own long terminal repeat, suggesting that
Positionally independent and exchangeable late budding functions of the Rous sarcoma virus and human immunodeficiency virus Gag proteins.: J Virol. 1995 Sep;69(9):5455-60. Unique Identifier : AIDSLINE MED/95363955; Parent LJ; Bennett RP; Craven RC; Nelle TD; Krishna NK; Bowzard JB; Wilson CB; Puffer BA; Montelaro RC; Wills JW; Department of Microbiology and Immunology, Pennsylvania State; University College of Medicine, Hershey 17033, USA.; The Gag proteins of Rous sarcoma virus and human immunodeficiency virus (HIV) each contain a function involved in a late step in budding, defects in which result in the accumulation of these molecules at the plasma membrane. In the Rous sarcoma virus Gag protein (Pr76gag), this assembly domain is associated with a PPP
Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promoters.: J Virol. 1995 Sep;69(9):5485-96. Unique Identifier : AIDSLINE MED/95363959; Horer M; Weger S; Butz K; Hoppe-Seyler F; Geisen C; Kleinschmidt JA; Deutsches Krebsforschungszentrum, Forschungsschwerpunkt; Angewandte Tumorvirologie, Heidelberg, Germany.; The four Rep proteins encoded by adeno-associated virus type 2 (AAV-2) inhibit transcription of their own promoters and of several heterologous promoters. To gain insight into the molecular mechanism of Rep-mediated transcription repression, we studied the effects of the four Rep proteins on the accumulation of mRNA t
Efficient expression of the human papillomavirus type 16 L1 protein in epithelial cells by using Rev and the Rev-responsive element of human immunodeficiency virus or the cis-acting transactivation element of simian retrovirus type 1.: J Virol. 1995 Sep;69(9):5607-20. Unique Identifier : AIDSLINE MED/95363974; Tan W; Felber BK; Zolotukhin AS; Pavlakis GN; Schwartz S; Microbiology and Tumorbiology Center, Karolinska Institute,; Stockholm, Sweden.; Production of the human papillomavirus (HPV) late gene products L1 and L2 is limited to terminally differentiated keratinocytes. Here, we demonstrate that mRNA encoding the HPV-16 L1 capsid protein contains cis-acting RNA elements that inhibit expression at the posttranscriptional level. While cytoplasmic L1 mRNA is d
Variability of human immunodeficiency virus type 1 group O strains isolated from Cameroonian patients living in France.: J Virol. 1995 Sep;69(9):5640-9. Unique Identifier : AIDSLINE GENBANK/U24712; Loussert-Ajaka I; Chaix ML; Korber B; Letourneur F; Gomas E; Allen E; Ly TD; Brun-Vezinet F; Simon F; Saragosti S; Laboratoire de Virologie, Hopital Bichat-Claude Bernard, Paris,; France.; Human immunodeficiency virus type 1 (HIV-1) nucleotide sequences encoding p24Gag and the Env C2V3 region were obtained from seven patients who were selected on the basis of having paradoxical seronegativity on a subset of HIV enzyme-linked immunosorbent assay detection kits and having atypical Western blot (immunoblot
Highly purified quiescent human peripheral blood CD4+ T cells are infectible by human immunodeficiency virus but do not release virus after activation.: J Virol. 1995 Sep;69(9):5659-65. Unique Identifier : AIDSLINE MED/95363979; Tang S; Patterson B; Levy JA; Department of Medicine, University of California School of; Medicine, San Francisco 94143, USA.; Previous studies have suggested that resting CD4+ lymphocytes can be infected by human immunodeficiency virus (HIV), but viral production is inhibited. If these cells are activated, progeny virions are released. The present data indicate that CD4+ lymphocytes in the G0/G1 stage of the cell cycle which have been highly
Mapping domains of retroviral integrase responsible for viral DNA specificity and target site selection by analysis of chimeras between human immunodeficiency virus type 1 and visna virus integrases.: J Virol. 1995 Sep;69(9):5687-96. Unique Identifier : AIDSLINE MED/95363982; Katzman M; Sudol M; Department of Medicine, Milton S. Hershey Medical Center,; Pennsylvania State University College of Medicine, Hershey 17033,; USA.; Human immunodeficiency virus type 1 (HIV-1) and visna virus integrases were purified from a bacterial expression system and assayed on oligonucleotide substrates derived from each terminus of human immunodeficiency virus type 1 and visna virus linear DNA. Three differences between the proteins were identified, includi
Nucleocapsid protein effects on the specificity of retrovirus RNA encapsidation.: J Virol. 1995 Sep;69(9):5716-22. Unique Identifier : AIDSLINE MED/95363985; Zhang Y; Barklis E; Vollum Institute for Advanced Biomedical Research, Oregon Health; Sciences University, Portland 97201-3098, USA.; We have analyzed the roles of Gag protein nucleocapsid (NC) domains in the packaging or encapsidation of retroviral RNAs into virus particles. We found that mutation of both zinc finger motifs of the human immunodeficiency virus (HIV) NC domain reduced but did not eliminate encapsidation of the HIV viral RNA. However,
A human recombinant Fab identifies a human immunodeficiency virus type 1-induced conformational change in cell surface-expressed CD4.: J Virol. 1995 Sep;69(9):5734-42. Unique Identifier : AIDSLINE MED/95363987; Bachelder RE; Bilancieri J; Lin W; Letvin NL; Harvard Medical School, Beth Israel Hospital, Boston,; Massachusetts 02215, USA.; To explore the role of the CD4 molecule in human immunodeficiency virus (HIV) infection following initial virus-CD4 binding, we have characterized CD4-specific antibodies raised by immunizing an HIV-1-infected human with human recombinant soluble CD4 (rsCD4). Fabs were selected from a human recombinant Fab library con
Persistence of attenuated rev genes in a human immunodeficiency virus type 1-infected asymptomatic individual.: J Virol. 1995 Sep;69(9):5743-53. Unique Identifier : AIDSLINE +; Iversen AK; Shpaer EG; Rodrigo AG; Hirsch MS; Walker BD; Sheppard HW; Merigan TC; Mullins JI; Department of Microbiology and Immunology, Stanford University; School of Medicine, California 94305-5402, USA.; With the goal of examining the functional diversity of human immunodeficiency virus type 1 (HIV-1) env genes within the peripheral blood mononuclear cells of an asymptomatic individual, we substituted four complete env genes into the replication-competent NL4-3 provirus. Despite encoding full-length open reading frame
Nucleotide sequence variation of the envelope protein gene identifies two distinct genotypes of yellow fever virus.: J Virol. 1995 Sep;69(9):5773-80. Unique Identifier : AIDSLINE MED/95363991; Chang GJ; Cropp BC; Kinney RM; Trent DW; Gubler DJ; Division of Vector-Borne Infectious Diseases, Centers for Disease; Control and Prevention, Fort Collins, Colorado 80522, USA.; The evolution of yellow fever virus over 67 years was investigated by comparing the nucleotide sequences of the envelope (E) protein genes of 20 viruses isolated in Africa, the Caribbean, and South America. Uniformly weighted parsimony algorithm analysis defined two major evolutionary yellow fever virus lineages desig
The amino terminus of Tax is required for interaction with the cyclic AMP response element binding protein.: J Virol. 1995 Sep;69(9):5806-11. Unique Identifier : AIDSLINE MED/95363996; Goren I; Semmes OJ; Jeang KT; Moelling K; Max-Planck-Institut fuer Molekulare Genetik, Berlin (Dahlem),; Federal Republic of Germany.; Tax of human T-cell leukemia virus type 1 was analyzed for interaction with the cyclic AMP response element binding protein (CREB) in vitro with and without Tax response element DNA. Mutations in the carboxy terminus of Tax (L296G and L320G) did not affect binding to CREB and led to supershifts. In contrast, mutants w
High levels of anti-human immunodeficiency virus type 1 (HIV-1) memory cytotoxic T-lymphocyte activity and low viral load are associated with lack of disease in HIV-1-infected long-term nonprogressors.: J Virol. 1995 Sep;69(9):5838-42. Unique Identifier : AIDSLINE MED/95364003; Rinaldo C; Huang XL; Fan ZF; Ding M; Beltz L; Logar A; Panicali D; Mazzara G; Liebmann J; Cottrill M; et al; Department of Pathology, University of Pittsburgh School of; Medicine, Pennsylvania, USA.; Lack of disease in long-term nonprogressors with human immunodeficiency virus type 1 (HIV-1) infection was strongly associated with very low copy numbers of HIV-1 DNA and RNA in peripheral blood mononuclear cells and plasma and the presence of high levels of anti-HIV-1 CD8+ memory cytotoxic T lymphocytes specific for
Fate of the human immunodeficiency virus type 1 provirus in infected cells: a role for vpr.: J Virol. 1995 Sep;69(9):5883-9. Unique Identifier : AIDSLINE MED/95364012; Planelles V; Bachelerie F; Jowett JB; Haislip A; Xie Y; Banooni P; Masuda T; Chen IS; Department of Microbiology and Immunology, UCLA School of; Medicine 90094-1678, USA.; We investigated the fate of human immunodeficiency virus type 1 (HIV-1) viral DNA in infected peripheral blood lymphocytes and immortalized T-cell lines by using a replication-defective HIV-1. We observed that integrated HIV-1 DNA and viral gene expression decrease over time. A frameshift mutation in vpr resulted in m
Sequences in the human immunodeficiency virus type 1 U3 region required for in vivo and in vitro integration.: J Virol. 1995 Sep;69(9):5904-7. Unique Identifier : AIDSLINE MED/95364015; Reicin AS; Kalpana G; Paik S; Marmon S; Goff S; Department of Medicine, Columbia College of Physicians and; Surgeons, New York, New York 10032, USA.; A series of mutants with alterations in the U3 region of the human immunodeficiency virus type 1 long terminal repeat were made, and the effects of these mutations were evaluated both in vitro and in vivo. When the subterminal 6 to 8 nucleotides of the U3 long terminal repeat were mutated, the resulting provirus was u
Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity.: J Virol. 1995 Sep;69(9):5908-11. Unique Identifier : AIDSLINE MED/95364016; Engelman A; Craigie R; Laboratory of Molecular Biology, National Institute of Diabetes; and Digestive and Kidney Diseases, Bethesda, Maryland 20892-0560,; USA.; The integrase protein from human immunodeficiency virus type 1 (HIV-1) has generally been reported to require Mn2+ for efficient in vitro activity. We have reexamined the divalent metal ion requirements of HIV-1 integrase and find that the protein is capable of promoting efficient 3 processing and DNA strand transfer
The tax mutation at nucleotide 7959 of human T-cell leukemia virus type 1 (HTLV-1) is not associated with tropical spastic paraparesis/HTLV-1-associated myelopathy but is linked to the cosmopolitan molecular genotype [letter; comment]: J Virol. 1995 Sep;69(9):5925-7. Unique Identifier : AIDSLINE MED/95364019; Mahieux R; de The G; Gessain A
Intermittent shedding of human immunodeficiency virus in semen: implications for sexual transmission.: J Urol. 1995 Sep;154(3):1035-40. Unique Identifier : AIDSLINE MED/95364027; Krieger JN; Coombs RW; Collier AC; Ho DD; Ross SO; Zeh JE; Corey L; Department of Urology, Medicine and Statistics, University of; Washington, Seattle, USA.; PURPOSE: We attempt to increase our understanding of human immunodeficiency virus (HIV) shedding in semen. MATERIALS AND METHODS: We followed 16 seropositive men for up to 27 months by HIV cocultivation, with a subset evaluated using the polymerase chain reaction. RESULTS: The proportion with at least 1 HIV positive s
Lower extremity lymphedema caused by acquired immune deficiency syndrome-related Kaposi's sarcoma: case report and review of the literature.: J Vasc Surg. 1995 Aug;22(2):178-81. Unique Identifier : AIDSLINE MED/95364116; Allen PJ; Gillespie DL; Redfield RR; Gomez ER; Department of Vascular Surgery, Walter Reed Army Medical Center,; Washington, DC 20307, USA.; A case of severe lymphedema of the lower extremity caused by obstruction by human immunodeficiency virus-associated Kaposi s sarcoma is presented. A review of the signs and symptoms of obstructive lymphedema and Kaposi s sarcoma is provided. Early recognition of this clinical entity may allow use of simple preventativ
Youth risk behavior surveillance--United States, 1993.: J Sch Health. 1995 May;65(5):163-71. Unique Identifier : AIDSLINE MED/95364348; Kann L; Warren CW; Harris WA; Collins JL; Douglas KA; Collins ME; Williams BI; Ross JG; Kolbe LJ; Division of Adolescent and School Health, Centers for Disease; Control and Prevention, Atlanta, GA 30341, USA.; Priority health risk behaviors that contribute to the leading causes of mortality, morbidity, and social problems among youth and adults often are established during youth, extend into adulthood, and are interrelated. The Youth Risk Behavior Surveillance System (YRBSS) monitors six categories of priority health risk b
Student opinions of condom distribution at a Denver, Colorado, high school.: J Sch Health. 1995 May;65(5):181-5. Unique Identifier : AIDSLINE MED/95364351; Fanburg JT; Kaplan DW; Naylor KE; Dept. of Pediatrics, University of Colorado, School of Medicine,; Denver 80218, USA.; Over the past two decades, the reported number of women and men who have had intercourse by age 18 has increased by approximately 20%. Concomitant increases occurred in the incidence of teen-age pregnancies and sexually transmitted diseases (STDs), including HIV. Increasing condom availability within schools has been
[Mortality from chronic liver disease in patients with HIV infection (letter)]: Med Clin (Barc). 1995 Jun 3;105(1):38. Unique Identifier : AIDSLINE MED/95364443; Jover R; Gutierrez A; Boix V; Portilla J
[HIV and tuberculosis at Venhalsan in Stockholm (letter)]: Lakartidningen. 1995 Jul 12;92(28-29):2717. Unique Identifier : AIDSLINE MED/95364480; Bratt G; Qvarner H; Grutzmeier S; Nilsson A; Hedman P; Sandstrom E
Can we prevent azole resistance in fungi?: Lancet. 1995 Aug 19;346(8973):454-5. Unique Identifier : AIDSLINE MED/95364499; Denning DW; University of Manchester, UK.
Oxidized cholesterol modulates age-related change in lipid metabolism in rats.: Lipids. 1995 May;30(5):405-13. Unique Identifier : AIDSLINE MED/95364593; Osada K; Kodama T; Noda S; Yamada K; Sugano M; Laboratory of Food Science, Kyushu University, School of; Agriculture, Fukuoka, Japan.; For three weeks, male Sprague-Dawley rats at either four weeks (young) or eight months (adult) of age were pair-fed one of the purified diets free of or containing either 0.2% of oxidized cholesterol mixture (cholesterol oxidation products) or 0.2% of cholesterol. Although the food intake was similar, dietary oxidized
[HTLV-I and HTLV-II viruses: fifteen years after their description]: Med Trop (Mars). 1995;55(1):17-20. Unique Identifier : AIDSLINE MED/95364654; Delaporte E; Laboratoire de Retrovirologie ORSTOM, Montpellier, France.
[Cambodia: the undermining by AIDS or the difficult rebuilding of a destroyed country]: Med Trop (Mars). 1995;55(1):21-5. Unique Identifier : AIDSLINE MED/95364655; L'Her P; Merlin M; Rith DN; Service de Sante des Armees, Hopital CALMETTE, Phnom Penh,; Cambodge.
[Round pulmonary lesions after returning from French Guyana. Six cases of american pulmonary histoplasmosis]: Med Trop (Mars). 1995;55(1):55-60. Unique Identifier : AIDSLINE MED/95364663; Bonnet D; Balandraud P; Lonjon T; Rey P; Van de Walle JP; Cador L; Jancovici R; Martet G; Branquet D; De Muizon H; Service de Pneumologie, l'Hopital d'Instruction des Armees; LAVERAN, Marseille, France.; From 1989 to 1994, 71 patients were hospitalized for diagnosis of round lung lesions including 49 servicemen under the age of 45 years who had been stationed in tropical areas. In 6 of these servicemen, the diagnosis was pulmonary histoplasmosis at the tertiary stage of histoplasmoma. All had done duty in French
[Severe pulmonary and meningeal cryptococcosis in an immunocompetent Cambodian]: Med Trop (Mars). 1995;55(1):61-4. Unique Identifier : AIDSLINE MED/95364664; L'Her P; Savuth C; Than T; San KK; Vuthea KS; Leang S; Sophouen N; Arborio M; Service de Medecine, Hopital CALMETTE, Paris, France.; A chest x-ray showing a large tumor-like opacity in the left lower lobe and endoscopy visualizing a budding mass suggested a diagnosis of bronchial carcinoma in a 55-year old, tobacco-smoking Cambodian who consulted for hemoptysis and altered general status. Histological study of bronchial biopsies allowed differentia
['95 pneumology update. Progress and perspectives in pneumology. Paradigms of change (II)]: Med Klin. 1995 Jun 15;90(6):343-57. Unique Identifier : AIDSLINE MED/95364729; Kroegel C; Buhl R; Muller-Querheim J; Wertzel H; Rabe K; Swoboda L; Matthys H; Hasse J; Magnussen H; Virchow JC; Abteilung Pneumologie, Medizinische Kliniken, Albert-Ludwigs-; Universitat Freiburg.
Oral ganciclovir as maintenance treatment for cytomegalovirus retinitis in patients with AIDS. Syntex Cooperative Oral Ganciclovir Study Group [see comments]: N Engl J Med. 1995 Sep 7;333(10):615-20. Unique Identifier : AIDSLINE MED/95364858; Drew WL; Ives D; Lalezari JP; Crumpacker C; Follansbee SE; Spector SA; Benson CA; Friedberg DN; Hubbard L; Stempien MJ; et al; UCSF/Mt. Zion Medical Center 94120, USA.; BACKGROUND. Cytomegalovirus retinitis, a sight-threatening infection associated with the acquired immunodeficiency syndrome (AIDS), currently requires lifelong intravenous treatment. An effective oral treatment would be an important advance. METHODS. We compared oral with intravenous ganciclovir in an open-label, rand
Images in clinical medicine. Cytomegalovirus retinitis in AIDS.: N Engl J Med. 1995 Sep 7;333(10):637. Unique Identifier : AIDSLINE MED/95364862; Keunen JE; Rothova A; Academisch Ziekenhuis Utrecht, The Netherlands.
New therapies for cytomegalovirus retinitis [editorial; comment]: N Engl J Med. 1995 Sep 7;333(10):658-9. Unique Identifier : AIDSLINE MED/95364868; Holland GN; Tufail A
Cytomegalovirus retinitis and low CD4+ T-lymphocyte counts [letter]: N Engl J Med. 1995 Sep 7;333(10):670. Unique Identifier : AIDSLINE MED/95364881; Baldassano V; Dunn JP; Feinberg J; Jabs DA
Marijuana, the AIDS wasting syndrome, and the U.S. government [letter]: N Engl J Med. 1995 Sep 7;333(10):670-1. Unique Identifier : AIDSLINE MED/95364882; Grinspoon L; Bakalar JB; Doblin R
A human nucleoporin-like protein that specifically interacts with HIV Rev.: Nature. 1995 Aug 10;376(6540):530-3. Unique Identifier : AIDSLINE GENBANK/X89478; Fritz CC; Zapp ML; Green MR; Howard Hughes Medical Institute, Program in Molecular Medicine,; University of Massachusetts Medical Center, Worcester 01605, USA.; The Rev protein of human immunodeficiency virus type 1 (HIV-1) facilitates the nuclear export of unspliced and partly spliced viral RNAs. Rev contains an RNA binding domain, required for interaction with HIV-1 RNA, and an effector domain, required for RNA-bound Rev to function. The Rev effector domain is believed to i
An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection.: Nature. 1995 Aug 17;376(6541):594-6. Unique Identifier : AIDSLINE MED/95364953; Wynn TA; Cheever AW; Jankovic D; Poindexter RW; Caspar P; Lewis FA; Sher A; Immunobiology Section, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892, USA.; The harmful fibrosis which often occurs in the context of infectious disease involves the excessive deposition of connective tissue matrix, particularly collagen, and is mostly resistant to pharmacological and immunological intervention. In schistosomiasis, fibrosis is associated with the granulomatous response to par
Recognition of bZIP proteins by the human T-cell leukaemia virus transactivator Tax.: Nature. 1995 Aug 17;376(6541):602-5. Unique Identifier : AIDSLINE MED/95364956; Perini G; Wagner S; Green MR; Howard Hughes Medical Institute, University of Massachusetts; Medical Center, Worcester 01605, USA.; Human T-cell leukaemia virus type I (HTLV-I) Tax protein increases the DNA binding of many cellular transcription factors that contain a basic region-leucine zipper (bZIP) DNA-binding domain. bZIP domains comprise a leucine-rich dimerization motif and a basic region that mediates DNA contact. How Tax recognizes divers
Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax.: Nature. 1995 Aug 17;376(6541):606-8. Unique Identifier : AIDSLINE MED/95364957; Baranger AM; Palmer CR; Hamm MK; Giebler HA; Brauweiler A; Nyborg JK; Schepartz A; Department of Chemistry, Yale University, New Haven, Connecticut; 06520, USA.; Tax protein activates transcription of the human T-cell leukaemia virus type I (HTLV-I) genome through three imperfect cyclic AMP-responsive element (CRE) target sites located within the viral promoter. Previous work has shown that Tax interacts with the bZIP element of proteins that bind the CRE target site to promot
Evaluation of the anticancer property of a new alpha-methylene-gamma-lactone derivative of phthalimide.: Neoplasma. 1995;42(3):129-32. Unique Identifier : AIDSLINE MED/95364967; Sanyal U; Dutta S; Das H; Department of Chemotherapy, Chittaranjan National Cancer; Institute, Calcutta, India.; The anticancer property of a new alpha-methylene-gamma-lactone derivative of phthalimide (2, NSC 640168) was evaluated in two murine ascitic tumors namely Ehrlich ascites carcinoma (EAC) and sarcoma-180 (S-180) by in vivo screenings and in a battery of human tumor cell lines by in vitro screening. It was found that th
Human immunodeficiency virus infection in women in Auckland: an evolving epidemic.: N Z Med J. 1995 Jul 14;108(1003):263-5. Unique Identifier : AIDSLINE MED/95365075; Shew R; Say J; Ellis-Pegler R; Thomas M; Diseases Unit, Auckland Hospital.; AIMS. To study the epidemiology, presenting features and outcome of HIV infection among women in Auckland. METHODS. Retrospective review of the medical records of all HIV infected women cared for by the adult infectious disease unit or the sexual health clinic at Auckland Hospital up to the end of December, 1993. RESU
The immunogenicity of Haemophilus influenzae type b conjugate (HbOC) vaccine in human immunodeficiency virus-infected and uninfected infants.: Pediatr Infect Dis J. 1995 May;14(5):350-4. Unique Identifier : AIDSLINE MED/95365166; Kale KL; King JC Jr; Farley JJ; Vink PE; Cimino CO; Paradiso PR; Department of Pediatrics, University of Maryland School of; Medicine, Baltimore 21201, USA.; Enzyme-linked immunosorbent assay polyribosyl ribitol phosphate (PRP) antibody responses to Haemophilus influenzae type b conjugate vaccine (HbOC) given at 2, 4 and 6 months of age were retrospectively compared in 23 human immunodeficiency virus (HIV) and 24 non-HIV-infected infants. HIV-infected infants were divided
Maternal acceptance of voluntary human immunodeficiency virus antibody testing during the newborn period with the Guthrie card.: Pediatr Infect Dis J. 1995 May;14(5):376-81. Unique Identifier : AIDSLINE MED/95365171; Walter EB; Elliott AJ; Regan AN; Drucker RP; Clements DA; Wilfert CM; Duke Vaccine and Infectious Epidemiology Unit, Department of; Pediatrics, Duke University Medical Center, Durham, NC 27704,; USA.; In order to provide the opportunity for women delivering newborns to have human immunodeficiency virus (HIV) testing we piloted a hospital-based voluntary HIV testing program during the newborn period using the Guthrie card. During the study period 789 women were offered newborn HIV antibody testing. Test acceptance d
Seroreversion in human immunodeficiency virus-exposed but uninfected infants.: Pediatr Infect Dis J. 1995 May;14(5):382-7. Unique Identifier : AIDSLINE MED/95365172; Chantry CJ; Cooper ER; Pelton SI; Zorilla C; Hillyer GV; Diaz C; Department of Pediatrics, University of Puerto Rico School of; Medicine, San Juan.; The goal of this study was to describe seroreversion (SR) in a cohort of human immunodeficiency virus-exposed but uninfected infants. Groups of patients who seroreverted very early or late were examined for salient clinical and immunologic characteristics of the mother or infant. The mean time (+/- s.d.) to serorevers
Acute renal failure in a human immunodeficiency virus-infected child secondary to bilateral fungus ball formation.: Pediatr Infect Dis J. 1995 May;14(5):401-3. Unique Identifier : AIDSLINE MED/95365181; Papaevangelou V; Lawrence R; Kaul A; Lefluer R; Ambrosino M; Krasinski K; Borkowsky W; Department of Pediatrics, New York University Medical Center, NY,; USA.
Present and future challenges of immunizations on the health of our patients.: Pediatr Infect Dis J. 1995 May;14(5):445-9. Unique Identifier : AIDSLINE MED/95365193; Gershon AA; Department of Pediatrics, Columbia University College of; Physicians and Surgeons, New York, NY, USA.; A recent analysis demonstrated a change in incidence approaching 100% for diseases against which we routinely immunize in the United States . At present, measles, mumps, rubella, invasive Haemophilus disease, poliomyelitis, diphtheria and tetanus are well-controlled but not eliminated.
[Diagnostic methods for HIV infections]: Postepy Hig Med Dosw. 1994;48(4):325-44. Unique Identifier : AIDSLINE MED/95365251; Szczepanek A; Plucienniczak A; Zaklad Badawczo-Wdrozeniowy i Inzynierii Genetycznej Terpol,; Przedsiebiorstwo Farmaceutyczne SA w Sieradzu.
[Biological properties of interleukin 10]: Postepy Hig Med Dosw. 1994;48(4):363-70. Unique Identifier : AIDSLINE MED/95365253; Lacki JK; Wiktorowicz KE; Zaklad Alergologii i Immunologii Klinicznej Akademii Medycznej w; Poznaniu.; Interleukin-10 (IL-10) is produced predominantly by T-helper lymphocytes and macrophages. IL-10 inhibits lymphocyte-induced cytokine production (CSIF--cytokine synthesis inhibitory factor), cooperates in B lymphocytes activation as well as macrophages--monocytes deactivation (MDF--macrophage deactivating factor). Due
[Biology of interleukin 6 (IL-6) and its significance in the pathogenesis of some diseases]: Postepy Hig Med Dosw. 1994;48(5):565-87. Unique Identifier : AIDSLINE MED/95365265; Robak T; II Klinika Chorob Wewnetrznych Akademii Medycznej w Lodzi.; In the paper numerous activities of IL-6 toward various normal and neoplastic cells are reviewed. The role of this cytokine in pathophysiology of a various disease including infections and inflammatory and autoimmune diseases as well as in leukaemias, lymphomas and other neoplastic diseases is presented. Potential cli
[Primary T lymphoma of the bladder in a HIV infected patient (letter)]: Presse Med. 1995 May 20;24(18):869. Unique Identifier : AIDSLINE MED/95365288; Zahar JR; Mortier E; Michon C; Pouchot J; Toublanc M; Vinceneux P
[Muscular localization of bacillary angiomatosis (letter)]: Presse Med. 1995 May 27;24(19):915. Unique Identifier : AIDSLINE MED/95365302; Bossi P; Mortier E; Simonpoli AM; Molinie V; Pouchot J; Vinceneux P
[Treatment of cerebral toxoplasmosis in AIDS with cotrimoxazole (letter; comment)]: Presse Med. 1995 May 27;24(19):917. Unique Identifier : AIDSLINE MED/95365306; Finielz P; Chuet C; Ramdane M; Guiserix J
[Tuberculosis in a Parisian pneumology department: 151 cases]: Presse Med. 1995 Jun 3;24(20):933-6. Unique Identifier : AIDSLINE MED/95365309; Brechot JM; Fiscel C; Stelianides S; Bouvet A; Rochemaure J; Service de Pneumologie, Laboratoire de Microbiologie (AB),; Hotel-Dieu, Paris.; OBJECTIVES: The incidence of tuberculosis has risen since 1992. We studied cases observed in our department to search for factors favouring this increased incidence. METHODS: A retrospective assessment of 151 cases of tuberculosis observed over a 3 year period in a department of pneumology in Paris was performed. RESU
[Cerebral infarction in human immunodeficiency virus infection]: Presse Med. 1995 Jun 3;24(20):937-8. Unique Identifier : AIDSLINE MED/95365310; Blanche P; Toulon P; de La Blanchardiere A; Sicard D; Service de Medecine interne, Hopital Cochin, Universite Rene; Descartes, Paris.; Patients infected with the human immunodeficiency virus (HIV) appear to have a high risk of ischaemic cerebral events. We observed two cases of cerebral infarction in patients with acquired immune deficiency syndrome (AIDS). In the first case, a 38-year-old homosexual with no cardiovascular risk other than smoking pre
[Secondary sclerosing cholangitis]: Presse Med. 1995 Jun 3;24(20):948-52. Unique Identifier : AIDSLINE MED/95365313; Amor A; Chapoutot C; Michel J; Pageaux GP; Larrey D; Michel H; Service d'Hepatogastroenterologie, Hopital Saint-Eloi,; Montpellier.; Secondary sclerosing cholangitis leads to slow and often irreversible destruction of the walls of both intra- and extrahepatic bile ducts. As for primary sclerosing cholangitis, clinical signs and laboratory findings reveal cholestasis. The diagnosis is confirmed by retrograde endoscopic cholangiography which shows na
[Tracheal stenosis, an unusual mode of revealing Burkitt's lymphoma in AIDS (letter)]: Presse Med. 1995 Jun 3;24(20):958. Unique Identifier : AIDSLINE MED/95365316; Perrin C; Vandenbos F; Galibert A; Dumon MC; Limouse L; Thyss A; Blaive B
Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular cofactors and Tat.: Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7153-7. Unique Identifier : AIDSLINE MED/95365326; Wu-Baer F; Sigman D; Gaynor RB; Department of Internal Medicine, University of Texas Southwestern; Medical Center, Dallas 75235-8594, USA.; The regulation of human immunodeficiency virus type 1 (HIV-1) gene expression in response to Tat is dependent on an element downstream of the HIV-1 transcriptional initiation site designated the trans-activating region (TAR). TAR forms a stable stem-loop RNA structure in which a 3-nt bulge structure and a 6-nt loop st
Resistance to human immunodeficiency virus type 1 infection conferred by transduction of human peripheral blood lymphocytes with ribozyme, antisense, or polymeric trans-activation response element constructs.: Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7272-6. Unique Identifier : AIDSLINE MED/95365350; Sun LQ; Pyati J; Smythe J; Wang L; Macpherson J; Gerlach W; Symonds G; R. W. Johnson Pharmaceutical Research Institute-Sydney, New South; Wales, Australia.; Human peripheral blood lymphocytes (PBLs) were transduced with a number of recombinant retroviruses including RRz2, an LNL6-based virus with a ribozyme targeted to the human immunodeficiency virus (HIV) tat gene transcript inserted within the 3 region of the neomycin-resistance gene; RASH5, and LNHL-based virus conta
CD4+ blood lymphocytes are rapidly killed in vitro by contact with autologous human immunodeficiency virus-infected cells.: Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7312-6. Unique Identifier : AIDSLINE MED/95365358; Nardelli B; Gonzalez CJ; Schechter M; Valentine FT; Department of Medicine, New York University Medical Center, NY; 10016, USA.; We have investigated the ability of human immunodeficiency virus (HIV)-infected cells to kill uninfected CD4+ lymphocytes. Infected peripheral blood mononuclear cells were cocultured with autologous 51Cr-labeled uninfected cells. Rapid death of the normal CD4-expressing target population was observed following a brief
Increased mutation frequency of feline immunodeficiency virus lacking functional deoxyuridine-triphosphatase.: Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7480-4. Unique Identifier : AIDSLINE MED/95365391; Lerner DL; Wagaman PC; Phillips TR; Prospero-Garcia O; Henriksen SJ; Fox HS; Bloom FE; Elder JH; Department of Molecular Biology, Scripps Research Institute, La; Jolla, CA 92037, USA.; Feline immunodeficiency virus (FIV) encodes the enzyme deoxyuridine-triphosphatase (DU; EC 3.6.1.23) between the coding regions for reverse transcriptase and integrase in the pol gene. Here, we report the in vivo infection of cats with a DU- variant of the PPR strain of FIV and compare its growth properties and tissue
Persistent infection of rhesus macaques with T-cell-line-tropic and macrophage-tropic clones of simian/human immunodeficiency viruses (SHIV).: Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7490-4. Unique Identifier : AIDSLINE GENBANK/M38427; Luciw PA; Pratt-Lowe E; Shaw KE; Levy JA; Cheng-Mayer C; Department of Medical Pathology, University of California, Davis; 95616, USA.; To elucidate the functions of human immunodeficiency virus type 1 (HIV-1) genes in a nonhuman primate model, we have constructed infectious recombinant viruses (chimeras) between the pathogenic molecular clone of simian immunodeficiency virus (SIV) SIVmac239 and molecular clones of HIV-1 that differ in phenotypic prop
Single cell analysis of cytokine gene coexpression during CD4+ T-cell phenotype development.: Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7565-9. Unique Identifier : AIDSLINE MED/95365407; Bucy RP; Karr L; Huang GQ; Li J; Carter D; Honjo K; Lemons JA; Murphy KM; Weaver CT; Department of Pathology, University of Alabama at Birmingham; 35233, USA.; CD4+ T cells from alpha beta-T-cell receptor transgenic mice were analyzed for coexpression of cytokine mRNAs during phenotype development using a double-label in situ hybridization technique. T cells that produced cytokines in the primary response were a fraction of the activated population, and only a minority of th
Support for hospital-based HIV testing and counseling: a national survey of hospital marketing executives.: Public Health Rep. 1995 Jul-Aug;110(4):467-75. Unique Identifier : AIDSLINE MED/95365513; Boscarino JA; Steiber SR; Department of Epidemiology and Biostatistics, University of; California at San Francisco 94105, USA.; Today, hospitals are involved extensively in social marketing and promotional activities. Recently, investigators from the Centers for Disease Control and Prevention (CDC) estimated that routine testing of hospital patients for human immunodeficiency virus (HIV) could identify more than 100,000 patients with previousl
CDC Clearinghouse offers new HIV-AIDS Treatment Information Service [news]: Public Health Rep. 1995 Jul-Aug;110(4):510. Unique Identifier : AIDSLINE MED/95365519
[Plasma fibronectin in chronic liver disease--marker of fibrosis?]: Przegl Lek. 1995;52(4):129-32. Unique Identifier : AIDSLINE MED/95365536; Simon K; Zalewska M; Gladysz A; Rotter K; Piszko P; Glowacki A; Katedry i Kliniki Chorob Zakaznych, Wroclawiu.; The determination of fibronectin (FN) concentration in plasma has been performed in the group of 77 patients (60-with various chronic liver diseases, 6-with AIDS IVc, 11-healthy patients). The purpose of this study was: evaluation of the value of plasma FN determination in assessment the degree of liver fibrosis and t
Evolution of pulmonary HIV-1 infection in a patient with Pneumocystis carinii pneumonia.: Respir Med. 1995 May;89(5):373-6. Unique Identifier : AIDSLINE MED/95365553; Clarke JR; Coker RJ; Harris JR; Mitchell DM; Department of Medical Microbiology, St. Mary's Hospital Medical; School, London, U.K.
Dose-dependent systemic human immunodeficiency virus infection of SCID-hu mice after intraperitoneal virus injection.: Res Virol. 1995 Mar-Apr;146(2):101-12. Unique Identifier : AIDSLINE MED/95365615; Grandadam M; Cesbron JY; Candotti D; Vinatier D; Pauchard M; Capron A; Debre P; Huraux JM; Autran B; Agut H; Laboratoire de Bacteriologie-Virologie, CNRS EP57, CERVI,; Hopital Pitie-Salpetriere, Paris, France.; SCID mice were engrafted with human foetal liver, thymus and lung. Human cells were subsequently detected among peripheral blood leukocytes for 81% of tested animals and in tissue implants for 100% of tested animals. SCID-hu mice received intraperitoneal injections of human immunodeficiency virus type 1 (HIV1) at from
Purification and characterization of a factor which inhibits retrovirus replication.: Res Virol. 1995 Mar-Apr;146(2):113-23. Unique Identifier : AIDSLINE MED/95365616; Krief P; Lawrence D; Alileche A; Plaisance S; Jasmin C; Semmel M; INSERM Unite 268, Villejuif, France.; Chick embryo cells (CEC) secrete a factor which inhibits HIV1 replication. Non-productive infection of CEC with vesicular stomatitis virus increases 5-10-fold the synthesis of this factor. After purification by FPLC the biological activity is associated with a heat-resistant protein of approximately 150 kDa, composed
A simplified method for quantitation of human immunodeficiency virus type 1 (HIV1) RNA in plasma: clinical correlates.: Res Virol. 1995 Mar-Apr;146(2):151-8. Unique Identifier : AIDSLINE MED/95365620; Stricker RB; Zhu YS; Elswood BF; HemaCare Corporation, San Francisco, CA 94108, USA.; Human immunodeficiency virus type 1 (HIV1) RNA was quantitated in the plasma of HIV1-seropositive patients using a simplified guanidinium-based extraction technique, reverse transcriptase (RT) and the polymerase chain reaction (PCR). Plasma samples were obtained from 15 HIV1-seronegative individuals and 38 HIV1-seropo
Advantage of a rapid extraction method of HIV1 DNA suitable for polymerase chain reaction.: Res Virol. 1995 Mar-Apr;146(2):159-62. Unique Identifier : AIDSLINE MED/95365621; Vignoli C; de Lamballerie X; Zandotti C; Tamalet C; de Micco P; Laboratoire de Virologie, Hopital de la Timone, Marseille,; France.; We describe a new protocol for extraction of DNA suitable for HIV1 gene amplification from clinical samples using Chelex-100 chelating resin. Comparison was made with the classic proteinase K extraction method; 154 specimens were extracted with both methods and subjected to PCR (polymerase chain reaction). The Chelex-
Nucleotide sequences of human T-lymphotropic virus type I (HTLV-I) from a family cluster with tropical spastic paraparesis/HTLV-I-associated myelopathy.: Res Virol. 1995 Mar-Apr;146(2):93-9. Unique Identifier : AIDSLINE MED/95365622; Renjifo B; Osterman J; Borrero I; Essex M; Department of Cancer Biology, Harvard School of Public Health,; Boston, MA 02115, USA.; We describe nucleotide sequences of human T-lymphotropic virus type I (HTLV-I) proviruses from three symptomatic family members with tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM) from Tumaco, Colombia . Polymera
Pulmonary lymphoid disorders.: Semin Diagn Pathol. 1995 May;12(2):158-71. Unique Identifier : AIDSLINE MED/95365633; Koss MN; Department of Pulmonary and Mediastinal Pathology, Armed Forces; Institute of Pathology, Washington, DC 20306-6000, USA.; Organized lymphoid aggregates are normally found within the walls of bronchi in many species and may occur, under conditions of disease, in humans. This bronchus-associated lymphoid tissue (BALT) can be viewed as an organizing principle to explain the behavior and distribution of many pulmonary lymphoid proliferations
Why Brazil should not be a site for AIDS vaccine trials [editorial]: Rev Paul Med. 1994 Jul-Sep;112(3):577-9. Unique Identifier : AIDSLINE MED/95365702; de Sa CA
Acquired immunodeficiency syndrome in forensic autopsies.: Rev Paul Med. 1994 Jul-Sep;112(3):580-6. Unique Identifier : AIDSLINE MED/95365703; Prints CD; de Mello JA; Guidugli RB; Cury CG; From May 1985 to May 1989, 126 necropsies were performed at the Sao Paulo City Morgue on cadavers of individuals AIDS victims whose unnatural deaths had prompted police investigations. One hundred and nineteen males and 17 females were included. Ages were most commonly in the 20-to-30 year range. Fifty four deaths occ
Behcet's syndrome/AIDS/cerebral toxoplasmosis: an unusual association.: Rev Paul Med. 1994 Jul-Sep;112(3):587-90. Unique Identifier : AIDSLINE MED/95365704; Chahade WH; Soares V de F; Guimaraes T; Berbert SO; Szwarc IS; Levi GC; Department of Rheumatology, Hospital do Servidor Publico; Estadual de Sao Paulo, Brazil.; Few cases of AIDS associated to manifestations suggesting Behcet s syndrome have been reported. This case is of a young married woman who presented, during a period of 7 years, clinical manifestations consistent with the late diagnosis of Behcet s syndrome, when she developed recurrent lymphomonocytic meningoencephali
Women: absent term in the AIDS research equation [news]: Science. 1995 Aug 11;269(5225):777-80. Unique Identifier : AIDSLINE MED/95365781; Cohen J
Global approaches to the promotion of women's health.: Science. 1995 Aug 11;269(5225):789-90. Unique Identifier : AIDSLINE MED/95365783; Mongella G; Fourth World Conference on Women, United Nations, New York, NY; 10017, USA.
Klausner follows own advice at NCI [news]: Science. 1995 Aug 18;269(5226):912-3. Unique Identifier : AIDSLINE MED/95365803; Marshall E
Universal precautions for the prevention of HIV and HBV infection in health care settings. Committee for Science and Education, Medical Association of South Africa.: S Afr Med J. 1995 May;85(5):381-3. Unique Identifier : AIDSLINE MED/95365888; OBJECTIVE. To outline the principles guiding the deliberate actions that should be taken in health care settings to prevent the spread of pathogens, especially HIV and hepatitis B virus (HBV), to patients and health care workers (HCWs). OUTCOMES. Universal precautions should be implemented in all health care settings.
HIV testing and informed consent [letter; comment]: S Afr Med J. 1995 May;85(5):392, 394-5. Unique Identifier : AIDSLINE MED/95365898; Dyssell J
Incidence of HIV infection in first-time blood donors [letter]: S Afr Med J. 1995 May;85(5):396-7. Unique Identifier : AIDSLINE MED/95365899; Buckle GC; Webb GL
Administration of anti-CD4 monoclonal antibody with intrathymic injection of alloantigen results in rat cardiac allograft tolerance.: Surgery. 1995 Aug;118(2):265-72; discussion 272-3. Unique Identifier : AIDSLINE MED/95365941; Arima T; Goss JA; Walp LA; Flye MW; Department of Surgery, Washington University School of Medicine,; St. Louis, Mo., USA.; BACKGROUND. We have previously reported the induction of donor-specific tolerance to cardiac allografts after intrathymic injection of alloantigen with simultaneous administration of antilymphocyte serum treatment to eliminate peripheral T cells. The present study determines whether prolongation of a fully major histo
Prognostic factors influencing the outcome in pneumocystis carinii pneumonia in patients with AIDS.: Thorax. 1995 Jun;50(6):668-71. Unique Identifier : AIDSLINE MED/95366013; Fernandez P; Torres A; Miro JM; Vieigas C; Mallolas J; Zamora L; Gatell JM; Valls ME; Riquelme R; Rodriguez-Roisin R; Hospital Clinic i Provincial, Departament de Medicina,; Universitat de Barcelona, Spain.; BACKGROUND--Studies attempting to identify the prognostic factors that influence the outcome of Pneumocystis carinii pneumonia (PCP) in patients with AIDS using a multivariate analysis are few. In order to identify those prognostic factors amenable to medical intervention, univariate and multivariate analyses were per
BAL fluid analysis and HIV-1 infection [letter; comment]: Thorax. 1995 Jun;50(6):701-2. Unique Identifier : AIDSLINE MED/95366025; Clarke JR; Williamson JD; Mitchell DM
[The characteristics of diagnosing homosexuality in examining a special population contingent]: Sud Med Ekspert. 1995 Apr-Jun;38(2):13-6. Unique Identifier : AIDSLINE MED/95366087; Bardenshtein LM; Ermolaev VS; Ovchinnikov VI; Ponomarev GN; In social terms homosexuality is one of the most dangerous sexual perversions, for it is subject to a strong social disapproval, affects the personality core, leads to social disadaptation, growth of anxiety, development of neurotic and depressive states, suicidal inclination, is conducive to the spread of syphilis an
[Detection of Toxoplasma gondii DNA in body fluids by polymerase chain reaction]: Wiad Parazytol. 1995;41(1):13-8. Unique Identifier : AIDSLINE MED/95366166; Golab E; Zaklad Parazytologii Lekarskiej, PZH, Warszawa.; The polymerase chain reaction (PCR) is used for in vitro amplification of specific DNA fragments. The PCR technique is based on the reiteration of a three-step process: denaturation DNA into single strands, annealing primers (specific synthetic oligonucleotides) to the DNA template and enzymatic extension from the pri
Mantle-cell lymphoma in a patient with human immunodeficiency viral infection.: Acta Haematol. 1995;93(2-4):101-4. Unique Identifier : AIDSLINE MED/95366263; Bilgrami S; Shafi N; Pesanti EL; Ciesielski T; Singh NT; Chen LL; Synnott V; Department of Medicine, Veterans Affairs Medical Center,; Newington, Conn., USA.; Rare cases of low-grade lymphomas have been described in patients with human immunodeficiency virus (HIV) infection. However, this is the first reported case of mantle-cell lymphoma, a type of low-grade lymphoma, in a patient who also had HIV infection. Salient clinical features included lymphocytosis, lymphadenopathy
Endovascular treatment of epistaxis in a patient with tuberculosis and a giant petrous carotid pseudoaneurysm.: AJNR Am J Neuroradiol. 1995 May;16(5):1084-6. Unique Identifier : AIDSLINE MED/95366354; Cross DT 3rd; Moran CJ; Brown AP; Oser AB; Goldberg DE; Diego J; Dacey RG; Department of Radiology, Washington University School of; Medicine, St Louis, Mo 63110, USA.; A 31-year-old man with pulmonary tuberculosis who did not have human immunodeficiency virus had massive epistaxis from a giant petrous internal carotid artery pseudoaneurysm. Endovascular trapping of the aneurysm was performed, curing the epistaxis. MR showed multiple enhancing brain lesions that resolved with additio
Needle-using practices within the sex industry. National AIDS Research Consortium.: Am J Drug Alcohol Abuse. 1995 May;21(2):241-55. Unique Identifier : AIDSLINE MED/95366436; Kail BL; Watson DD; Ray S; Fordham University Graduate School of Social Service, New York,; New York 10023, USA.; The addicted prostitute faces a risk of AIDS from both her sexual practices and intravenous drug use. While the sexual practices of these women have been studied, much less is known about their needle-using practices. We suggest women in the sex industry are more enmeshed in the drug-using scene and occupy a more cons
T cell counts from methadone and nonmethadone groups [letter]: Am J Drug Alcohol Abuse. 1995 May;21(2):283-4. Unique Identifier : AIDSLINE MED/95366439; Wodak A; Capelhorn J; Crofts N
Relationship of aminotransferases to liver histological status in chronic hepatitis C.: Am J Gastroenterol. 1995 Aug;90(8):1250-7. Unique Identifier : AIDSLINE MED/95366451; Haber MM; West AB; Haber AD; Reuben A; Department of Pathology, Yale University, New Haven, Connecticut,; USA.; OBJECTIVES: Serum aminotransferase levels characteristically fluctuate in chronic hepatitis C, but their relationship to grade (i.e., inflammatory activity) and stage (i.e., degree of fibrosis) of liver disease is uncertain. We therefore correlated aminotransferase levels and liver biopsy findings in 90 patients with
Diagnostic laparoscopy: a 5-year experience in a hepatology training program.: Am J Gastroenterol. 1995 Aug;90(8):1258-62. Unique Identifier : AIDSLINE MED/95366452; Vargas C; Jeffers LJ; Bernstein D; Reddy KR; Munnangi S; Behar S; Scott C; Parker T; Schiff ER; Center for Liver Diseases, University of Miami School of; Medicine, Florida, USA.; Diagnostic laparoscopy continues to have a role in the evaluation and diagnosis of acute and chronic liver diseases, primary and metastatic liver tumors, and peritoneal diseases. We retrospectively reviewed the records of 1794 diagnostic laparoscopies performed at our institution from 1987 to 1992 to identify the indi
Clinical correlates of subnormal vitamin B12 levels in patients infected with the human immunodeficiency virus.: Am J Hematol. 1995 Aug;49(4):318-22. Unique Identifier : AIDSLINE MED/95366505; Paltiel O; Falutz J; Veilleux M; Rosenblatt DS; Gordon K; Department of Medicine, Montreal General Hospital, McGill; University, Quebec, Canada.; OBJECTIVES: To determine the prevalence and describe the clinical correlates of subnormal cobalamin levels in subjects infected with the human immunodeficiency virus (HIV), and to assess its relationship to virus-mediated immunosuppression and/or anti-viral therapy. SETTING: Outpatient referral clinic in tertiary care
Third case of acute monocytic leukemia (M5) occurring in an HIV-seropositive man: a case report [letter]: Am J Hematol. 1995 Aug;49(4):356-7. Unique Identifier : AIDSLINE MED/95366514; Costello RT; Sainty D; Heuberger L; Gastaut JA; Bouabdallah R
A sensitive and specific polymerase chain reaction-based assay for the diagnosis of cytomegalovirus retinitis.: Am J Ophthalmol. 1995 Aug;120(2):219-26. Unique Identifier : AIDSLINE MED/95366535; McCann JD; Margolis TP; Wong MG; Kuppermann BD; Luckie AP; Schwartz DM; Irvine AR; Ai E; Francis I. Proctor Foundation for Research in Ophthalmology,; University of California, San Francisco 94122-0944, USA.; PURPOSE: To develop a sensitive and specific laboratory assay for the diagnosis of cytomegalovirus retinitis. METHOD: We used a polymerase chain reaction-based assay for detection of cytomegalovirus DNA in vitreous samples. We attempted to detect cytomegalovirus DNA in 19 vitreous
Aqueous and vitreous humor samples for the diagnosis of cytomegalovirus retinitis.: Am J Ophthalmol. 1995 Aug;120(2):252-3. Unique Identifier : AIDSLINE MED/95366541; Mitchell SM; Fox JD; Moorfields Eye Hospital, London, United Kingdom.; PURPOSE/METHODS: Techniques for detection of viral DNA based on the polymerase chain reaction are increasingly being applied to ocular fluids; however, the clinical significance of such findings can sometimes be unclear. Two patients had the acquired immunodeficiency syndrome (AIDS) in whom different herpesviruses wer
Implementing a tuberculosis control program.: Am J Infect Control. 1995 Apr;23(2):152-5. Unique Identifier : AIDSLINE MED/95366638; Williams J; Schneider N; Gilligan ME; Infection Control Department, St. Luke's/Roosevelt Hospital, New; York, NY 10019, USA.; Between January 1989 and December 1990, 26 patients acquired multidrug-resistant tuberculosis at our institution. Their exposures occurred when they were admitted to a ward where a patient with acid fast bacillus smear-positive pulmonary tuberculosis was also admitted. In 20 cases, the infectious patients were not iso
Infection control, human immunodeficiency virus, and home health care: II. Risk to the caregiver.: Am J Infect Control. 1995 Apr;23(2):78-81. Unique Identifier : AIDSLINE MED/95366644; Valenti WM; Community Health Network, Inc., Rochester, NY, USA.
Undocumented HIV infection [letter; comment]: Ann Intern Med. 1995 Sep 15;123(6):470; discussion 470-1. Unique Identifier : AIDSLINE MED/95366687; Andrews S; Tammaro D; Stein MD
Undocumented HIV Infection [letter; comment]: Ann Intern Med. 1995 Sep 15;123(6):470; discussion 470-1. Unique Identifier : AIDSLINE MED/95366688; Harrow AS
Host-directed therapy for AIDS [letter; comment]: Ann Intern Med. 1995 Sep 15;123(6):471-2. Unique Identifier : AIDSLINE MED/95366690; Stricker RB; Goldberg B
NF-kappa B transcription factor activation by hydrogen peroxide can be decreased by 2,3-dihydroxybenzoic acid and its ethyl ester derivative.: Arch Biochem Biophys. 1995 Aug 1;321(1):263-70. Unique Identifier : AIDSLINE MED/95366769; Sappey C; Boelaert JR; Legrand-Poels S; Grady RW; Piette J; Laboratory of Virology, University of Liege, Belgium.; Reactive oxygen species like hydrogen peroxide (H2O2) have been shown to serve as messengers in the induction of NF-kappa B and, hence, in the activation and replication of human immunodeficiency virus type 1 (HIV-1) in human cells. Several antioxidant compounds and iron chelators have been shown to interfere with bot
Kaposi's sarcoma of the bulbar conjunctiva as an initial clinical manifestation of acquired immunodeficiency syndrome [letter]: Arch Ophthalmol. 1995 Aug;113(8):978. Unique Identifier : AIDSLINE MED/95366921; Kurumety UR; Lustbader JM
Poly(ADP-ribose) polymerase activity in various U937 cell subclones with different susceptibility to HIV-1 infection: its dramatic decrease following persistent virus infection.: Biochem Biophys Res Commun. 1995 Aug 4;213(1):161-8. Unique Identifier : AIDSLINE MED/95366992; Tanaka Y; Yoshihara K; Kojima K; Itaya A; Kameoka M; Ikuta K; Kamiya T; Department of Biochemistry, Nara Medical University, Japan.; Poly(ADP-ribose) polymerase, a nuclear enzyme, is suggested to be involved in apoptotic cell death. It is also known that apoptotic cell death following HIV-1 infection is the most important feature of AIDS pathogenesis. Thus, to evaluate the relations between the enzyme and HIV-1 infection, we examined the enzyme act
Structural investigation and kinetic characterization of potential cleavage sites of HIV GP160 by human furin and PC1.: Biochem Biophys Res Commun. 1995 Aug 4;213(1):356-61. Unique Identifier : AIDSLINE MED/95367020; Brakch N; Dettin M; Scarinci C; Seidah NG; Di Bello C; Institute of Industrial Chemistry, University of Padua, Italy.; A key event in the biosynthesis of the human immunodeficiency virus is the maturation of the gp160 precursor generating gp120 and gp41, two proteins that are fundamental for the infective process. In vivo, gp160 is specifically cleaved at the 515-519 site (REKR decreases A), in spite of the presence in its sequence of
Biased T cell receptor V beta gene usage during specific stages of the development of autoimmune sialadenitis in the MRL/lpr mouse model of Sjogren's syndrome.: Arthritis Rheum. 1995 Aug;38(8):1077-84. Unique Identifier : AIDSLINE MED/95367069; Hayashi Y; Hamano H; Haneji N; Ishimaru N; Yanagi K; Department of Pathology, Tokushima University School of; Dentistry, Japan.; OBJECTIVE. To analyze the repertoire of T cell receptor (TCR) V beta gene transcribed and expressed within the autoimmune lesions of the salivary gland in the MRL/lpr mouse model of Sjogren s syndrome. METHODS. Monoclonal antibodies (MAb) were used to determine the prevalence of selected V gene elements on T cell infi
[Reversible pulmonary overload with clofazimine (Lamprene) in HIV-positive subjects (letter)]: Ann Pathol. 1995;15(3):224-5. Unique Identifier : AIDSLINE MED/95367099; Finet JF; Similowski T; Derenne JP; Le Charpentier Y
Statistical issues in the design of HIV vaccine trials.: Annu Rev Public Health. 1995;16:1-22. Unique Identifier : AIDSLINE MED/95367101; Schaper C; Fleming TR; Self SG; Rida WN; Department of Biostatistics, University of Washington, Seattle; 98195, USA.; HIV vaccine trials present significant challenges related to trial endpoints, vaccine efficacy measurement, and the role of nonvaccine interventions. Infection is a valid endpoint for detecting sterilizing immunity. But if the vaccine prevents AIDS without preventing infection, infection may be a misleading surrogate.
Infectious risks for health care workers.: Annu Rev Public Health. 1995;16:141-64. Unique Identifier : AIDSLINE MED/95367104; Clever LH; LeGuyader Y; Department of Occupational Health, California Pacific Medical; Center, San Francisco 94120, USA.; Although health care has been practiced for eons and although hundreds of thousands of workers are engaged in it, we know distressingly little about ways to prevent work-related infectious illnesses in this important group. Assumptions may be dangerous and expensive: Are universal precautions effective; when are respi
International aspects of the AIDS/HIV epidemic.: Annu Rev Public Health. 1995;16:253-82. Unique Identifier : AIDSLINE MED/95367110; Kimball AM; Berkley S; Ngugi E; Gayle H; Department of Health Services and Epidemiology, University of; Washington, Seattle 98195, USA.; This review provides the reader with pertinent information on the epidemiology, prevention, and new technologies of the ongoing HIV pandemic. These aspects are key to international policy discussions surrounding the public health response to the international spread of HIV. Our understanding of the impact of AIDS on o
Uncommon invasive mycoses in AIDS [editorial]: AIDS. 1995 May;9(5):411-20. Unique Identifier : AIDSLINE MED/95367210; Cunliffe NA; Denning DW
Different patterns of HIV-1-specific cytotoxic T-lymphocyte activity after primary infection.: AIDS. 1995 May;9(5):421-6. Unique Identifier : AIDSLINE MED/95367211; Lamhamedi-Cherradi S; Culmann-Penciolelli B; Guy B; Ly TD; Goujard C; Guillet JG; Gomard E; Laboratory of Immunology of Cellular and Molecular Interactions,; Cochin Hospital, Paris, France.; OBJECTIVE: To analyse the HIV-1-specific cytotoxic T-lymphocyte (CTL) responses of nine HIV-seropositive subjects in relation with primary infection. METHODS: Anti-HIV CTL were generated by in vitro stimulation of peripheral mononuclear cells obtained from HIV-seropositive donors at various times after primary infecti
Viral phenotype and host-cell susceptibility to HIV-1 infection as risk factors for mother-to-child HIV-1 transmission.: AIDS. 1995 May;9(5):427-34. Unique Identifier : AIDSLINE MED/95367212; Ometto L; Zanotto C; Maccabruni A; Caselli D; Truscia D; Giaquinto C; Ruga E; Chieco-Bianchi L; De Rossi A; Institute of Oncology, University of Padova, Italy.; OBJECTIVE: To investigate the role of maternal HIV-1 isolate phenotype and a child s cell susceptibility/resistance to viral infection in mother-to-child HIV-1 transmission. PATIENTS AND METHODS: Forty-nine women were studied at the time of delivery. Primary isolates, obtained by culturing patient peripheral blood mon
Simultaneous introduction of distinct HIV-1 subtypes into different risk groups in Russia, Byelorussia and Lithuania.: AIDS. 1995 May;9(5):435-9. Unique Identifier : AIDSLINE MED/95367213; Lukashov VV; Cornelissen MT; Goudsmit J; Papuashvilli MN; Rytik PG; Khaitov RM; Karamov EV; de Wolf F; Human Retrovirus Laboratory, University of Amsterdam, The; Netherlands.; OBJECTIVE: To investigate genotypes and serotypes of HIV-1 variants in Russia , Byelorussia and Lithuania . PATIENTS AND METHODS: Sera from 20 HIV-1-infected individuals were tested in an enzyme-li
Reduced toxoplasmastatic activity of monocytes and monocyte-derived macrophages from AIDS patients is mediated via prostaglandin E2.: AIDS. 1995 May;9(5):441-5. Unique Identifier : AIDSLINE MED/95367214; Delemarre FG; Stevenhagen A; Kroon FP; van Eer MY; Meenhorst PL; van Furth R; Department of Infectious Diseases, University Hospital, Leiden,; The Netherlands.; OBJECTIVE: To establish the role of prostaglandin E2 (PGE2) formed and released by monocytes and monocyte-derived macrophages (MDM) in the reduced toxoplasmastatic activity of these cells. DESIGN: Determination of PGE2 levels in the serum of AIDS patients, the release of PGE2 by monocytes and MDM from AIDS patients, t
Onset of clinical signs in children with HIV-1 perinatal infection. Italian Register for HIV Infection in Children.: AIDS. 1995 May;9(5):455-61. Unique Identifier : AIDSLINE MED/95367216; Galli L; de Martino M; Tovo PA; Gabiano C; Zappa M; Giaquinto C; Tulisso S; Vierucci A; Guerra M; Marchisio P; et al; Department of Paediatrics, University of Florence, Italy.; OBJECTIVE: To investigate the timing of onset of each clinical sign in infants and children with HIV-1 perinatal infection. DESIGN AND METHODS: A total of 200 HIV-1-infected children followed-up from birth were studied. Failure and conditional probabilities were estimated by the Kaplan-Meier product-limit method. Cox
A dose comparison study of didanosine in patients with very advanced HIV infection who are intolerant to or clinically deteriorate on zidovudine. German ddI Trial Group.: AIDS. 1995 May;9(5):463-9. Unique Identifier : AIDSLINE MED/95367217; Jablonowski H; Arasteh K; Staszewski S; Ruf B; Stellbrink HJ; Schrappe M; Stoehr A; Haase W; Schomaker U; von Eisenhart Rothe B; et al; Department for Gastroenterology, Hepatology and Infectiology,; Heinrich-Heine University, Dusseldorf, Germany.; OBJECTIVE: Zidovudine (ZDV) is the only antiretroviral drug which has been shown to reduce mortality in patients with symptomatic HIV disease, but its use is restricted by intolerance in a significant proportion of patients. Additionally, the efficacy of ZDV therapy appears to decrease after prolonged treatment partic
Intravenous versus oral ganciclovir: European/Australian comparative study of efficacy and safety in the prevention of cytomegalovirus retinitis recurrence in patients with AIDS. The Oral Ganciclovir European and Australian Cooperative Study Group.: AIDS. 1995 May;9(5):471-7. Unique Identifier : AIDSLINE MED/95367218; OBJECTIVES: To evaluate the efficacy and safety of oral ganciclovir for the maintenance treatment of cytomegalovirus ( CMV ) retinitis in patients with AIDS. DESIGN: A 20-week, randomized, multicentre, open-label study. Progres
Behavioural interventions for HIV/AIDS prevention.: AIDS. 1995 May;9(5):479-86. Unique Identifier : AIDSLINE MED/95367219; Oakley A; Fullerton D; Holland J; Social Science Research Unit, University of London, Institute of; Education, UK.; OBJECTIVES: The aim of this study was to identify and critically review behavioural interventions in the HIV prevention and sexual health fields. METHODS: Electronic and hand searches were conducted to retrieve relevant published and unpublished reports of outcome evaluations. A methodological review was carried out t
HIV testing patterns: where, why, and when were persons with AIDS tested for HIV?: AIDS. 1995 May;9(5):487-92. Unique Identifier : AIDSLINE MED/95367220; Wortley PM; Chu SY; Diaz T; Ward JW; Doyle B; Davidson AJ; Checko PJ; Herr M; Conti L; Fann SA; et al; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, Georgia 30333, USA.; OBJECTIVE: To describe the location of, primary reason for, and time between the first positive HIV test and AIDS diagnosis in a sample of persons with newly diagnosed AIDS. DESIGN: Interviews supplementing information routinely collected through AIDS case reporting. SETTING: Eleven US states and cities. PATIENTS: Per
Changes in the injecting risk behaviour of injecting drug users in London, 1990-1993.: AIDS. 1995 May;9(5):493-501. Unique Identifier : AIDSLINE MED/95367221; Hunter GM; Donoghoe MC; Stimson GV; Rhodes T; Chalmers CP; Department of Psychiatry, Charing Cross and Westminster Medical; School, University of London, UK.; OBJECTIVE: To describe changes in the injecting risk behaviour of injecting drug users (IDU) in London between 1990 and 1993. DESIGN: Injecting risk behaviour was measured over 4 years (1990-1993) in a serial point HIV prevalence study of 2062 IDU recruited in both drug treatment and non-treatment community-based sett
Migration and HIV-1 seroprevalence in a rural Ugandan population.: AIDS. 1995 May;9(5):503-6. Unique Identifier : AIDSLINE MED/95367222; Nunn AJ; Wagner HU; Kamali A; Kengeya-Kayondo JF; Mulder DW; Medical Research Council (UK) Programme on AIDS, Uganda Virus; Research Institute, Entebbe.; OBJECTIVE: To study the association between change of residence and HIV-1 serostatus in a rural Ugandan population. DESIGN: A longitudinal cohort study. METHODS: As part of the annual surveillance of a population cohort of approximately 10,000 individuals in a rural subcounty of southwest Uganda, information has been
The relational determinants of condom use with commercial sex partners in Thailand [see comments]: AIDS. 1995 May;9(5):507-15. Unique Identifier : AIDSLINE MED/95367223; Morris M; Pramualratana A; Podhisita C; Wawer MJ; Department of Sociology, Columbia University, New York, New York; 10027, USA.; OBJECTIVE: To analyze the extent and determinants of condom use with commercial sex partners among lower socioeconomic status groups in the Thai population. DESIGN: Respondents were sampled in Udon Thani, Saraburi and Bangkok in 1992. Completed sample size was 678 women in brothels, 330 male truck drivers and 1,075 me
The epidemiology of HIV and syphilis among male commercial sex workers in northern Thailand [see comments]: AIDS. 1995 May;9(5):517-21. Unique Identifier : AIDSLINE MED/95367224; Kunawararak P; Beyrer C; Natpratan C; Feng W; Celentano DD; de Boer M; Nelson KE; Khamboonruang C; Royal Thai Ministry of Public Health, Department of Communicable; Disease Control, Chiang Mai.; OBJECTIVE: To examine the prevalence and incidence of HIV and syphilis, and risk behaviors for these infections, among 1,172 male commercial sex workers (CSW) followed prospectively from 1989 to 1994 in Chiang Mai, northern Thailand . METHODS: Twice yearly visits were conducted by
Condom use in Thailand: how much is it slowing the HIV/AIDS epidemic? [editorial; comment]: AIDS. 1995 May;9(5):523-5. Unique Identifier : AIDSLINE MED/95367225; Mastro TD; Limpakarnjanarat K
Failure to infect lower primate species with SIVcpz [letter]: AIDS. 1995 May;9(5):527-8. Unique Identifier : AIDSLINE MED/95367226; Beer B; Peeters M; Norley SG; van der Groen G; Fransen LK; Willkommen H; Kurth R
Kinetics of detection of antibodies to HIV-1 and plasma p24 antigens during a severe primary HIV-1 infection [letter]: AIDS. 1995 May;9(5):528-9. Unique Identifier : AIDSLINE MED/95367227; Burin des Roziers N; Sotto A; Arnaud A; Saissi G; Nasar O; Jourdan J
Comparison of the rates of CD4 count decline among HIV-infected women and men [letter]: AIDS. 1995 May;9(5):529-30. Unique Identifier : AIDSLINE MED/95367228; Beatty ME; Broisman L
ABO blood groups and rhesus group antigens in epidemic Kaposi's sarcoma [letter]: AIDS. 1995 May;9(5):530-1. Unique Identifier : AIDSLINE MED/95367229; Brook MZ; Gudza I; Gabriel R
Cytomegalovirus encephalitis resistant to anti-cytomegalovirus therapy [letter]: AIDS. 1995 May;9(5):531-2. Unique Identifier : AIDSLINE MED/95367230; Holida MD; Trigg ME; Rumelhart SL; Lee NF; Kook H; Peters C
Thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome in HIV-infected patients [letter]: AIDS. 1995 May;9(5):532-3. Unique Identifier : AIDSLINE MED/95367231; Bachmeyer C; Blanche P; Sereni D; Salmon D; Grateau G; Dreyfus F; Sicard D
Azole-resistant oropharyngeal and esophageal candidiasis in patients with AIDS [letter]: AIDS. 1995 May;9(5):533-4. Unique Identifier : AIDSLINE MED/95367232; Horn CA; Washburn RG; Givner LB; Peacock JE Jr; Pegram PS
Papular mucinosis in HIV-infected patients [letter]: AIDS. 1995 May;9(5):535-6. Unique Identifier : AIDSLINE MED/95367233; Moragon M; Sevila A; Colomina J; Banuls J; Botella R; Ivars J
Severe ulcers from an unconventional therapy against AIDS [letter]: AIDS. 1995 May;9(5):536. Unique Identifier : AIDSLINE MED/95367234; Santarossa S; Bernardi D; Tirelli U
Condom promotion strategies: what we need to know? [letter]: AIDS. 1995 May;9(5):537-8. Unique Identifier : AIDSLINE MED/95367235; Sharma V; Sharma A
A retrospective analysis of the prevalence of HIV seropositivity and its demographics in the normal healthy volunteer population of a phase-I clinical drug study unit [letter]: Br J Clin Pharmacol. 1995 Apr;39(4):463-4. Unique Identifier : AIDSLINE MED/95367424; Jagathesan R; Lewis LD; Mant TG
A Bayesian model for evaluating specificity of treatment effects in clinical trials.: Cancer Treat Res. 1995;75:155-75. Unique Identifier : AIDSLINE MED/95367428; Simon RM; Dixon DO; Freidlin B; Biometrics Research Branch, National Cancer Institute (NCI),; Bethesda, MD 20892, USA.
Issues in the design and analysis of AIDS clinical trials.: Cancer Treat Res. 1995;75:29-47. Unique Identifier : AIDSLINE MED/95367432; Dixon DO; Albert JM; National Institutes of Health, Solar Building, Room 2B21,; Bethesda, MD 20892, USA.
Elevated tumor necrosis factor-alpha in association with severe anemia in human immunodeficiency virus infection and Mycobacterium avium intracellulare infection.: Pediatr Hematol Oncol. 1995 May-Jun;12(3):221-30. Unique Identifier : AIDSLINE MED/95367442; Ellaurie M; Rubinstein A; George Washington University School of Medicine, Children's; National Medical Center, Washington, D.C., USA.; Mycobacterium avium intracellulare (MAI) infection is a serious opportunistic infection that occurs in children with human immunodeficiency virus (HIV) infection. In MAI the hematologic system is profoundly affected. In the present study the hematologic manifestations of MAI in 37 HIV-infected infants and children wer
Characterization of Mg(2+)-dependent 3'-processing activity for human immunodeficiency virus type 1 integrase in vitro: real-time kinetic studies using fluorescence resonance energy transfer.: Biochemistry. 1995 Aug 15;34(32):10205-14. Unique Identifier : AIDSLINE MED/95367549; Lee SP; Kim HG; Censullo ML; Han MK; Department of Biochemistry and Molecular Biology, Georgetown; University Medical Center, Washington, D.C. 20007, USA.; Human immunodeficiency virus type 1 integrase (HIV-1 IN) catalyzes the integration of HIV-1 DNA into the host chromosome. In vitro reactions with endogenous viral DNA require Mg2+ as the metal cofactor, whereas in vitro studies performed with short oligonucleotide substrates utilize Mn2+. In this study, we report that
Substrate-length-dependent activities of human immunodeficiency virus type 1 integrase in vitro: differential DNA binding affinities associated with different lengths of substrates.: Biochemistry. 1995 Aug 15;34(32):10215-23. Unique Identifier : AIDSLINE MED/95367550; Lee SP; Censullo ML; Kim HG; Han MK; Department of Biochemistry and Molecular Biology, Georgetown; University Medical Center, Washington, D.C. 20007, USA.; Human immunodeficiency virus type 1 integrase (HIV-IN) is an enzyme essential for the integration of viral DNA into the host chromosome, a process that is an attractive target for drug development. In vitro assays have been developed to study both components of the integration process, the 3 -processing and strand tra
[Analysis of restraint of the femur head. Experimental study of allograft of cold bone and autoclaved bone to kill the HIV virus]: Bull Assoc Anat (Nancy). 1995 Mar;79(244):11-3. Unique Identifier : AIDSLINE MED/95367696; Allogo JJ; Fischer LP; Gonon GP; Minchella P; Fessy MH; Clermont N; Morin A; Laboratoire d'Anatomie, Faculte de Medecine, Grange Blanche,; Lyon.; The retrovirus S.I.A.D. grown in marrow bone and iatrogenic infections may be possible after bone graft in following total hip arthroplasties. Previous investigators proposed several methods to kill the virus, but without bacteriological safety. They found 20 to 55% of loss on mechanical properties. The present study
Reprocessing of reusable medical devices.: ASAIO J. 1995 Apr-Jun;41(2):146-51. Unique Identifier : AIDSLINE MED/95367707; Malchesky PS; Chamberlain VC; Scott-Conner C; Salis B; Wallace C; STERIS Corporation, Mentor, Ohio, USA.; Advances in medical science and, in particular, minimally invasive surgical and diagnostic procedures have stimulated the development of new and improved medical devices. This has been made possible because of developments in engineering and material sciences. The design of devices for reusability is particularly impo
Dutch face up to blood scandal [news]: BMJ. 1995 Aug 5;311(7001):347. Unique Identifier : AIDSLINE MED/95367880; Sheldon T
Pneumococcal vaccine for HIV patients. Patients with HIV infection should be immunised... [letter; comment]: BMJ. 1995 Aug 5;311(7001):387-8. Unique Identifier : AIDSLINE MED/95367899; McDonald P; Lighton L; Anderson R
Sex and HIV/AIDS education in schools [editorial; comment] [see comments]: BMJ. 1995 Aug 12;311(7002):403. Unique Identifier : AIDSLINE MED/95367926; Kirby D
Russia delays HIV testing for foreigners [news]: BMJ. 1995 Aug 12;311(7002):407. Unique Identifier : AIDSLINE MED/95367931; Ingram M
Production of human immunodeficiency virus by chronically infected cells grown in protein-free medium.: Cell Biol Int. 1995 Jun;19(6):507-15. Unique Identifier : AIDSLINE MED/95368020; Pinter C; Siccardi AG; Clivio A; Dipartimento di Biologia e Genetica per le Scienze Mediche,; Universita degli Studi di Milano, Italy.; A human T cell line chronically infected with Human Immunodeficiency Virus (HIV) has been adapted to grow in a chemically defined, protein-free medium. Virus particles are produced at rates comparable to those of serum-supplemented cultures; virus preparations free of undesirable proteins can be produced in preparativ
Parasitic infections associated with HIV/AIDS in the Caribbean.: Bull Pan Am Health Organ. 1995 Jun;29(2):129-37. Unique Identifier : AIDSLINE MED/95368048; Robinson RD; Department of Zoology, University of the West Indies, Kingston,; Jamaica.; This review article seeks to highlight the significance for the Caribbean of major parasitic infections associated with AIDS, encourage awareness of these opportunistic parasites, and promote familiarity with appropriate diagnostic techniques and their clinical relevance. Specific agents considered include Pneumocysti
[Hemophagocytic syndrome in children infected by HIV. Apropos of 3 cases]: Arch Pediatr. 1995 May;2(5):442-6. Unique Identifier : AIDSLINE MED/95368112; Dalle JH; Dollfus C; Leverger G; Landman-Parker J; Tabone MD; Adam M; Courpotin C; Lasfargues G; Departement de pediatrie Edmond-Lesne, hopital d'enfants; Armand-Trousseau, Paris, France.; BACKGROUND--The hemophagocytic syndrome has previously been reported in different infectious diseases (EBV, CMV , tuberculosis...) but rarely in adults with AIDS and never in children suffering from AIDS. CASE REPORTS--A hemophagocytic syndrome was recognized durp
HIV malingering in the accident and emergency department.: J Accid Emerg Med. 1995 Mar;12(1):59-61. Unique Identifier : AIDSLINE MED/95368212; Ryan J; Taylor CB; Bryant GD; Nayagam AT; Sanders J; Department of Accident and Emergency Medicine, Royal Sussex; County Hospital, Brighton.; This paper reports a number of cases of patients attending an accident and emergency (A&E) department claiming to be HIV positive when they have been tested negative and are known to be negative by other departments in the hospital. The reasons for these patients claims are not always apparent. These patients may p
Reduced cytokine production in response to stimulation with dust mite antigen after cyclosporin A treatment of atopic dermatitis [letter]: Exp Dermatol. 1995 Apr;4(2):117-8. Unique Identifier : AIDSLINE MED/95368256; Kubota Y; Imayama S; Koga T; Hori Y
Lymphocytes, T and NK cells, in men occupationally exposed to mercury vapours.: Int J Occup Med Environ Health. 1995;8(1):49-56. Unique Identifier : AIDSLINE MED/95368292; Moszczynski P; Slowinski S; Rutkowski J; Bem S; Jakus-Stoga D; Regional Hospital Immunological Laboratory, Brzesko, Poland.; Lymphocytes, T-cells (CD3+), T-helper (CD4+) and T-suppressor (CD8+) as well as NK-cells (CD16+) counts were determined in the peripheral blood of 81 males occupationally exposed to metallic mercury vapours and of 36 non-exposed males using monoclonal antibodies in indirect immunofluorescence tests. Mean weighted merc
The confidentiality of medical information in the workplace.: J Occup Environ Med. 1995 May;37(5):583-93. Unique Identifier : AIDSLINE MED/95368394; Rischitelli DG; Division of Occupational Health, Johns Hopkins University School; of Hygiene and Public Health, Baltimore, MD 21205, USA.; Ethical dilemmas involving confidentiality issues are frequently encountered in occupational medicine. The occupational physician faces a unique challenge because in many circumstances, a physician-patient relationship, in the ordinary or legal sense, may not exist. The occupational physician often faces a conflicting
Zidovudine regimen in pediatric AIDS trial halted, other regimens shown superior [news]: Am J Health Syst Pharm. 1995 May 1;52(9):932. Unique Identifier : AIDSLINE MED/95368465
Human immunodeficiency virus infection in children.: Am J Health Syst Pharm. 1995 May 1;52(9):961-79. Unique Identifier : AIDSLINE MED/95368469; Hoernle EH; Reid TE; Department of Clinical Pharmacy Services, Cook County Hospital,; Chicago, IL, USA.; The transmission, diagnosis, and clinical manifestations of human immunodeficiency virus (HIV) infection in children up to 13 years of age are reviewed, and maintenance and prophylactic drug therapies for these patients are discussed. HIV can be transmitted from mother to infant in utero, during delivery, or through b
HIV transmission: rights of workers and patients [letter; comment]: Can Med Assoc J. 1995 Sep 1;153(5):520, 522. Unique Identifier : AIDSLINE MED/95368587; Harris JD
Psychiatrists campaign to attract colleagues to treat HIV-disease patients.: Can Med Assoc J. 1995 Sep 1;153(5):647-9. Unique Identifier : AIDSLINE MED/95368601; Birenbaum R; The shortage of psychiatrists willing to treat patients with HIV infection has become so severe the Canadian Psychiatric Association has launched a campaign to try and encourage more specialists to enter the field. At the heart of the campaign is a booklet, Consultant/Mentor Directory for HIV Disease and Psychiatry, t
Requests approaching 50,000 annually for emergency drug release program.: Can Med Assoc J. 1995 Sep 1;153(5):665-6. Unique Identifier : AIDSLINE MED/95368603; Robinson A; Health Canada s Emergency Drug Release Program, which allows physicians to acquire nonmarketed drugs to treat people with HIV infection, AIDS and other illnesses, handles about 44 000 requests annually. The executive director of the Drugs Directorate says the program s name is a misnomer, since few of the requests inv
Partial degradation of T-cell signal transduction molecules by contaminating granulocytes during protein extraction of splenic T cells from tumor-bearing mice.: Cancer Res. 1995 Sep 1;55(17):3840-6. Unique Identifier : AIDSLINE MED/95368642; Franco JL; Ghosh P; Wiltrout RH; Carter CR; Zea AH; Momozaki N; Ochoa AC; Longo DL; Sayers TJ; Komschlies KL; Laboratory of Experimental Immunology, Program Resources,; Inc/DynCorp, National Cancer Institute, Frederick Cancer Research; and Development Center, Frederick, Maryland 21702-1201, USA.; Flavone-8-acetic acid plus recombinant human interleukin 2 is a successful antitumor therapy in mice bearing the Renca murine renal cell carcinoma. This report demonstrates that T cells, particularly CD8+ T cells, are critical for the generation of this response. Initial experiments examining T-cell signal transductio
A simplified general method for determination of recombinant retrovirus titers.: Cell Struct Funct. 1995 Apr;20(2):177-83. Unique Identifier : AIDSLINE MED/95368745; Miyao Y; Shimizu K; Tamura M; Yamada M; Tamura K; Nakahira K; Kuriyama S; Hayakawa T; Ikenaka K; Department of Neurosurgery, Osaka University Medical School,; Japan.; To construct recombinant retroviruses with only a single active promoter, we introduced point mutations into the TATA box region of the 3 -LTR, and successfully obtained high-titer virus with sufficient self-inactivating activity. However, the viral titer could not be determined by the number of G418 resistant colonie
Synthesis of toddacoumaquinone, a coumarin-naphthoquinone dimer, and its antiviral activities.: Chem Pharm Bull (Tokyo). 1995 Jun;43(6):1039-41. Unique Identifier : AIDSLINE MED/95368748; Ishikawa T; Kotake K; Ishii H; Faculty of Pharmaceutical Sciences, Chiba University, Japan.; Toddacoumaquinone (1), a coumarin-naphthoquinone dimer, was synthesized through Diels-Alder reaction between 8-(1-acetoxy-3-methyl-1,3-butadienyl)-5,7-dimethoxycoumarin (15) and 2-methoxy-1,4-benzoquinone (5). The activities of 1 against several viruses were examined. A weak activity (EC50 = 10 micrograms/ml) was obse
Context framing to enhance HIV-antibody-testing messages targeted to African American women.: Health Psychol. 1995 May;14(3):247-54. Unique Identifier : AIDSLINE MED/95369218; Kalichman SC; Coley B; Department of Psychiatry and Mental Health Sciences, Medical; College of Wisconsin, Milwaukee 53226, USA.; African American women (N = 100) recruited from an urban clinic were randomly assigned to view 1 of 3 experimental videotapes promoting HIV testing: (a) an ethnicity-matched information control videotape; (b) the same ethnicity-matched videotape presented by an African American woman (gender-ethnicity-matched control
Understanding and promoting AIDS-preventive behavior: insights from the theory of reasoned action.: Health Psychol. 1995 May;14(3):255-64. Unique Identifier : AIDSLINE MED/95369219; Fisher WA; Fisher JD; Rye BJ; Department of Psychology, University of Western Ontario, London,; Canada.; Psychological determinants of AIDS-preventive behaviors were examined from the perspective of the theory of reasoned action in prospective studies of gay men, heterosexual university students, and heterosexual high school students. Across samples, preventive behaviors, and prospective intervals of 1 and 2 months dura
Psychosocial predictors of AIDS risk behavior and drug use behavior in homeless and drug addicted women of color.: Health Psychol. 1995 May;14(3):265-73. Unique Identifier : AIDSLINE MED/95369220; Nyamathi A; Stein JA; Brecht ML; School of Nursing, University of California, Los Angeles; 90024-6918, USA.; The present study examined a causal model consisting of personal and social resources, threat appraisal processes, coping styles, and barriers to risk reduction as predictors of general AIDS risk and specific drug use behaviors among homeless African American (N = 714) and Latina (N = 691) women. The model, which was
Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor.: EMBO J. 1995 Aug 1;14(15):3654-63. Unique Identifier : AIDSLINE GENBANK/U22339; Giri JG; Kumaki S; Ahdieh M; Friend DJ; Loomis A; Shanebeck K; DuBose R; Cosman D; Park LS; Anderson DM; Immunex Research and Development Corporation, Seattle, WA 98101,; USA.; Interleukin-15 (IL-15) is a novel cytokine of the four-helix bundle family which shares many biological activities with IL-2 , probably due to its interaction with the IL-2 receptor beta and gamma (IL-2R beta and gamma c) chains. We report here the characterization and
Persistent Epstein-Barr virus infection in a human T-cell line: unique program of latent virus expression.: EMBO J. 1995 Aug 1;14(15):3706-11. Unique Identifier : AIDSLINE MED/95369242; Yoshiyama H; Shimizu N; Takada K; Department of Virology and Parasitology, Yamaguchi University; School of Medicine, Japan.; The growth transforming potential of Epstein-Barr virus (EBV) for Burkitt s lymphoma and nasopharyngeal carcinoma is now extended to other neoplasia, such as Hodgkin s disease, peripheral T-cell tumor and gastric cancer. We have generated an EBV recombinant with a selectable marker at the viral thymidine kinase locus.
A novel expression vector composed of a regulatory element of the human leukosialin-encoding gene in different types of mammalian cells.: Gene. 1995 Jul 28;160(2):283-6. Unique Identifier : AIDSLINE MED/95369705; Xu A; Kudo S; Fukuda M; Alliance Pharmaceutical Corp., San Diego, CA 92121, USA.; The regulatory element (RE) of the human leukosialin (LS)-encoding gene, that encodes a major sialoglycoprotein of human leukocyte and platelet membranes, was used to develop a novel expression vector, pKX. The vector was constructed by cloning a RE fragment and the SV40 fragment containing polyadenylation and splicin
[Intensive prenatal diagnosis in HIV seropositivity is obsolete. Prenatal care--labor--puerperium]: Fortschr Med. 1995 Jun 20;113(17):20. Unique Identifier : AIDSLINE MED/95369752; Woraschk HJ
The effect of a single amino acid substitution within the V3 loop of HIV-1 gp120 on HLA-DR1-restricted CD4 T-cell recognition.: Immunology. 1995 Jun;85(2):176-83. Unique Identifier : AIDSLINE MED/95369818; Fernandez MH; Faith A; Higgins JA; Weber J; Rees AD; Department of Genito-Urinary Medicine and Communicable Diseases,; St Mary's Hospital Medical School, London, UK.; Viral variation has been proposed to play a role in the pathogenesis of human immunodeficiency virus type-1 (HIV-1) infection, and is an important consideration in vaccine design. During the course of an infection, isolates with sequence changes in CD8 T-cell and B-cell epitopes arise. To determine whether sequence va
Interaction of complement and specific antibodies with the external glycoprotein 120 of HIV-1.: Immunology. 1995 Jun;85(2):184-9. Unique Identifier : AIDSLINE MED/95369819; Prohaszka Z; Hidvegi T; Ujhelyi E; Stoiber H; Dierich MP; Susal C; Fust G; National Institute of Haematology, Blood Transfusion and; Immunology, Budapest, Hungary.; Previously we have investigated the interaction of human complement as well as one polyclonal and three human monoclonal antibody preparations with the human immunodeficiency virus type-1 (HIV-1) transmembrane recombinant glycoprotein (rgp41). A strong competition was found between the antibodies and deposited complem
Occurrence of interleukin-5 production by CD4- CD8- (double-negative) T cells in lungs of both normal and congenitally athymic nude mice infected with Toxocara canis.: Immunology. 1995 Jun;85(2):285-91. Unique Identifier : AIDSLINE MED/95369833; Takamoto M; Kusama Y; Takatsu K; Nariuchi H; Sugane K; Department of Parasitology, Shinshu University School of; Medicine, Matsumoto, Japan.; We studied cells in the lungs of BALB/c and BALB/c-nu/nu (nude) mice infected with Toxocara canis, which produced interleukin-5 (IL-5) in in vitro culture with larval excretory-secretory antigen (ESAg). The proportion of CD4+/CD8+/CD4- CD8- cells in lungs of both BALB/c and nude mice was unchanged before and after inf
Gastrointestinal manifestations of AIDS.: Gastroenterol Clin North Am. 1995 Jun;24(2):413-34. Unique Identifier : AIDSLINE MED/95369865; Yee J; Wall SD; University of California, San Francisco, USA.; As the AIDS epidemic continues to grow, it becomes increasingly important that physicians are aware of the gastrointestinal and abdominal diseases specific to this group of patients. Most AIDS patients exhibit gastrointestinal symptoms at some time during the course of their disease. Clinical AIDS is often determined
CD4+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract.: Infect Immun. 1995 Sep;63(9):3302-8. Unique Identifier : AIDSLINE MED/95369878; Su H; Caldwell HD; Immunology Section, Rocky Mountain Laboratories, National; Institute of Allergy and Infectious Diseases, Hamilton, Montana; 59840-2999, USA.; The ability of CD4+ and CD8+ T cells to adoptively immunize mice against Chlamydia trachomatis infection of the mouse genital tract was studied. Adoptive transfer experiments were performed with splenic CD4+ or CD8+ T cells obtained from mice following resolution of a primary genital tract infection and after a second
Sulfated polyanions block Chlamydia trachomatis infection of cervix-derived human epithelia.: Infect Immun. 1995 Sep;63(9):3520-6. Unique Identifier : AIDSLINE MED/95369910; Zaretzky FR; Pearce-Pratt R; Phillips DM; Population Council, New York, New York 10021, USA.; Using a cell line derived from the human cervix and a rapid fluorescence cytotoxicity assay, we have shown that Chlamydia trachomatis infection can be blocked by certain sulfated polysaccharides (carrageenan, pentosan polysulfate, fucoidan, and dextran sulfate) and glycosaminoglycans (heparin, heparan sulfate, and der
[Cellular immune defect caused by postoperative irradiation in patients with squamous epithelial carcinomas of the upper aerodigestive tract]: HNO. 1995 Jun;43(6):364-70. Unique Identifier : AIDSLINE MED/95370027; Maier H; Daniel V; Heimlich F; Frank C; Opelz G; Universitats-HNO-Klinik Heidelberg.; The effect of locoregional postoperative radiation therapy on cellular immunity was investigated in 11 patients with head and neck cancer. During the course of the radiation therapy, total lymphocyte counts, CD8+ lymphocyte counts and especially CD4+ lymphocyte counts decreased significantly. The mean CD4+ lymphocyte
Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase.: J Biol Chem. 1995 Aug 11;270(32):18929-34. Unique Identifier : AIDSLINE MED/95370204; Eriksson S; Xu B; Clayton DA; Department of Developmental Biology, Stanford University School; of Medicine, California 94305-5427, USA.; Saccharomyces cerevisiae mtDNA polymerase, isolated as a single 135-kDa recombinant polypeptide, showed high processivity and a capacity of use poly(dA).oligo(dT), poly(rA).oligo(dT), or primed bacteriophage M13 DNA as a template. In a primer extension assay, the enzyme exhibited an intrinsic 3 -5 -exonuclease activit
c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas.: J Biol Chem. 1995 Aug 11;270(32):18961-5. Unique Identifier : AIDSLINE MED/95370209; Chou TY; Hart GW; Dang CV; Biochemistry, Cellular, and Molecular Biology Training Program,; Johns Hopkins University School of Medicine, Baltimore, Maryland; 21205, USA.; c-Myc is a helix-loop leucine zipper phosphoprotein that heterodimerizes with Max and regulates gene transcription in cell proliferation, cell differentiation, and programmed cell death. Previously, we demonstrated that c-Myc is modified by O-linked N-acetylglucosamine (O-GlcNAc) within or nearby the N-terminal transc
HIV-1 envelope glycoproteins induce activation of activated protein-1 in CD4+ T cells.: J Biol Chem. 1995 Aug 18;270(33):19364-9. Unique Identifier : AIDSLINE MED/95370270; Chirmule N; Goonewardena H; Pahwa S; Pasieka R; Kalyanaraman VS; Pahwa S; Department of Pediatrics, North Shore University Hospital,; Carnell University Medical College, Manhasset, New York 11030,; USA.; Activation of CD4 positive T cells is a primary requirement for human immunodeficiency virus (HIV) entry, efficient HIV replication, and progression to AIDS, Utilizing CD4 positive T cell lines and purified T cells from normal individuals, we have demonstrated that native envelope glycoproteins of HIV, gp 160, can ind
HIV-1 non-specifically stimulates production of transforming growth factor-beta 1 transfer in primary astrocytes.: J Neuroimmunol. 1995 Jul;60(1-2):125-33. Unique Identifier : AIDSLINE MED/95370411; da Cunha A; Jackson RW; Vitkovic L; Section on Molecular Neuroscience, National Institute of Mental; Health, Bethesda, MD 20892, USA.; HIV-1 expression in monocytes/macrophages can be controlled by transforming growth factor-beta 1 (TGF-beta 1). TGF-beta 1 is present in astrocytes surrounding HIV-1-infected monocyte/macrophages in brain tissue from patients with AIDS but not from seronegative, normal individuals. We sought to determine whether or not
Operational issues in syringe exchanges: the New York City tagging alternative study.: J Community Health. 1995 Apr;20(2):111-23. Unique Identifier : AIDSLINE MED/95370451; Paone D; Des Jarlais DC; Caloir S; Clark J; Jose B; Chemical Dependency Institute, Beth Israel Medical Center, N.Y.,; NY 10003, USA.; It is estimated that 50% of the approximate 200,000 intravenous drug users (IDUs) in New York City (NYC) are infected with HIV. Syringe exchange, a common method of HIV prevention in many countries was legalized in NYC in 1992. As syringe exchange has gained public support and the number of functioning exchangers has
Protecting the weakest link: a proposal for universal, unblinded pediatric HIV testing, counselling and treatment.: J Community Health. 1995 Apr;20(2):125-41. Unique Identifier : AIDSLINE MED/95370452; Crawford C; Brooklyn Law School, NY 11201, USA.; This paper argues that a system of unblinded, universal testing, counseling and treatment for pediatric HIV should be implemented immediately in New York State. First, it argues that New York s health and social services bureaucracies, in conjunction with special interests that do not represent the interests of childr
The case against mandatory newborn screening for HIV antibodies.: J Community Health. 1995 Apr;20(2):143-59. Unique Identifier : AIDSLINE MED/95370453; Dumois AO; Community Family Planning Council, New York, NY 10010, USA.; The paper examines the controversy surrounding legislative proposals in New York State that would require amending the public health law s stringent confidentiality provisions; the legislation calls for unblinding the results of a 7-year old statewide HIV seroprevalence study that tests newborns for HIV antibodies in
Mandated life versus mandatory death: New York's disgraceful partner notification record.: J Community Health. 1995 Apr;20(2):161-70. Unique Identifier : AIDSLINE MED/95370454; Norwood C; Health Force: Women Against AIDS, Bronx, NY 10454, USA.; In New York City in 1993, there were some 18,000 positive HIV tests but only 350 partner notifications completed by the New York City Health Department. The bleak disparity between these two numbers should haunt us all. We will never know for certain how many lives could have been saved by universally available notifi
How I view the HIV epidemic as a Pentecostal.: J Community Health. 1995 Apr;20(2):171-5. Unique Identifier : AIDSLINE MED/95370455; Sepulveda W; II Spanish Pentecostal Church, Inc., Brooklyn, New York 11217,; USA.
HIV in the inner cities: epidemiologic trends and their influence on policy-making decisions.: J Community Health. 1995 Apr;20(2):177-81. Unique Identifier : AIDSLINE MED/95370456; Bastien A; Department of Preventive Medicine and Community Health, State; University of New York, Brooklyn 11203, USA.
HIV/AIDS in the Czech Republic.: J Community Health. 1995 Apr;20(2):183-4. Unique Identifier : AIDSLINE MED/95370457; Bruckova M; Jedlicka J; National Reference Laboratory on AIDS, National Institute of; Public Health, Prague, Czech Republic.
The Czech Republic's national AIDS program.: J Community Health. 1995 Apr;20(2):185-9. Unique Identifier : AIDSLINE MED/95370458; Walter G; Department of Epidemiology and Microbiology, Ministry of Health; of the Czech Republic, Prague.
HIV/AIDS legislation in the Czech Republic.: J Community Health. 1995 Apr;20(2):191-5. Unique Identifier : AIDSLINE MED/95370459; Krysova Z; Division of Hygiene and Epidemiology, Ministry of Health of the; Czech Republic, Prague.
Regional AIDS center activities in the Czech Republic.: J Community Health. 1995 Apr;20(2):197-201. Unique Identifier : AIDSLINE MED/95370460; Svejda J; Dlouhy P; Department of Infectious Diseases, Masaryk Hospital, Usti nad; Labem, Czech Republic.
Prophylaxis of opportunistic infections in HIV infection.: J Community Health. 1995 Apr;20(2):203-7. Unique Identifier : AIDSLINE MED/95370461; Svoboda J; 1st Medical School, Charles University, Prague, Czech Republic.
Clinical manifestations of atypical mycobacterioses in the Czech Republic.: J Community Health. 1995 Apr;20(2):209-12. Unique Identifier : AIDSLINE MED/95370462; Rozsypal H; Stankova M; Department of Infectious Diseases, Bulkova Teaching Hospital,; Prague, Czech Republic.
The different faces of the AIDS pandemic [editorial]: J Community Health. 1995 Apr;20(2):77-8. Unique Identifier : AIDSLINE MED/95370467; Imperato PJ
Key policy debates on HIV in the inner city [editorial]: J Community Health. 1995 Apr;20(2):79-82. Unique Identifier : AIDSLINE MED/95370468; Benker KE
HIV disease in the Czech Republic [editorial]: J Community Health. 1995 Apr;20(2):83-6. Unique Identifier : AIDSLINE MED/95370469; DeHovitz JA
Community planning: a national strategy to improve HIV prevention programs.: J Community Health. 1995 Apr;20(2):87-100. Unique Identifier : AIDSLINE MED/95370470; Valdiserri RO; Aultman TV; Curran JW; Division of STD/HIV Prevention, Centers for Disease Control and; Prevention, Atlanta, Georgia 30333, USA.; Beginning in fiscal year (FY) 1994, the Centers for Disease Control and Prevention (CDC), in collaboration with health departments and other human immunodeficiency virus (HIV) prevention partners, set in motion a significant innovation in HIV prevention programs: HIV Prevention Community Planning. This process, implem
The Charles Bonnet syndrome (pseudohallucinations) in an AIDS patient with cytomegalovirus retinitis.: J Nerv Ment Dis. 1995 Aug;183(8):549-50. Unique Identifier : AIDSLINE MED/95370768; Hartmann PM; Kosko DA; Cohn JA; York Hospital, Pennsylvania 17405, USA.
The lived experience of self-transcendence in women with AIDS.: J Obstet Gynecol Neonatal Nurs. 1995 May;24(4):314-8. Unique Identifier : AIDSLINE MED/95370985; Coward DD; University of Texas at Austin 78701, USA.; OBJECTIVE: To describe the lived experience of self-transcendence in women with AIDS, associated with increased sense of meaning and purpose, well-being, self-esteem, and connectedness with self and/or others. DESIGN: Exploratory-descriptive, using phenomenological research methods for the study approach, data collect
AIDS and HIV-related topics. Part I. Introduction.: J Am Podiatr Med Assoc. 1995 Jul;85(7):345. Unique Identifier : AIDSLINE MED/95371035; Tinkle JD; Cope R
History and epidemiology of acquired immune deficiency syndrome.: J Am Podiatr Med Assoc. 1995 Jul;85(7):346-51. Unique Identifier : AIDSLINE MED/95371036; Levy LA; California College of Podiatric Medicine, San Francisco 94115,; USA.; Acquired immune deficiency syndrome (AIDS) and human immunodeficiency virus (HIV) were first noticed in the US in 1981 and continue to spread today. Initially a disease associated completely with homosexual males, it is increasing in incidence and prevalence among heterosexual males and females, particularly, but not
Neurologic conditions affecting the lower extremities in HIV infection.: J Am Podiatr Med Assoc. 1995 Jul;85(7):352-61. Unique Identifier : AIDSLINE MED/95371037; Gilmer WS; Baylor College of Medicine, Houston, TX 77004, USA.; The vast majority of patients with human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) have symptoms or signs involving the feet and lower extremities. Patients presenting to podiatrists with foot complaints may, in fact, have neurologic complications of HIV originating in any level of th
Cutaneous manifestations of HIV-1 infection.: J Am Podiatr Med Assoc. 1995 Jul;85(7):362-74. Unique Identifier : AIDSLINE MED/95371038; Memar O; Cirelli R; Lee P; Tyring SK; Department of Microbiology/Immunology, University of Texas; Medical Branch, Galveston, USA.; Infection with the human immunodeficiency virus (HIV) leads to a chronic disarmament of the immune system. The process is progressive, having different manifestations as the status of the immune system slowly deteriorates. Some of the most common manifestations of HIV infection are cutaneous in origin, and they can ha
Guide to medications used to treat acquired immune deficiency syndrome.: J Am Podiatr Med Assoc. 1995 Jul;85(7):375-93. Unique Identifier : AIDSLINE MED/95371039; Rooney MD; Creighton University School of Pharmacy and Allied Health; Professions, Omaha, NE, USA.; Currently, there is no means to eradicate the human immunodeficiency virus (HIV) from the human body. Thus, drug therapy provides an important mechanism to slow viral replication and its damaging effects on the body. A review of the drugs used in the care of the patient with acquired immune deficiency syndrome (AIDS)
Rehabilitation management of the lower extremity in HIV disease.: J Am Podiatr Med Assoc. 1995 Jul;85(7):394-402. Unique Identifier : AIDSLINE MED/95371040; McReynolds MA; The sequelae of human immunodeficiency virus (HIV) disease include a host of devastating conditions involving the lower extremity. These include rheumatologic dysfunction, Kaposi s sarcoma, peripheral neuropathies, and skin ulcers. Pain, weakness, and loss of range of motion caused by these conditions can lead to chan
Teenagers swap pill for condom [news]: J R Soc Health. 1995 Jun;115(3):140. Unique Identifier : AIDSLINE MED/95371059
HIV-positive people, HIV-negative partners.: J Sex Marital Ther. 1995 Summer;21(2):127-40. Unique Identifier : AIDSLINE MED/95371149; Harmon L; Volker M; Lambda Counseling Center, Miami, Florida, USA.; More relationships exist today between HIV-positive and HIV-negative partners. This article explores the underlying dynamics that might account for this phenomenon. Codependency theories may explain these relationships for some couples. For other couples, it is suggested that positive-negative homosexual relationships
[Analysis of in vivo cell proliferation of ATL using SCID mice]: Rinsho Ketsueki. 1995 Jun;36(6):573-7. Unique Identifier : AIDSLINE MED/95371179; Imada K; Takaori-Kondo A; Uchiyama T; Laboratory of AIDS Immunology, Kyoto University.; We made a model of in vivo cell proliferation of leukemic cells from adult T cell leukemia (ATL) patients using severe combined immunodeficient (SCID) mice. SCID mice injected with ATL cells from 6 of 8 ATL patients were found to have the tumor. DNA analysis revealed that the clone of the cells proliferating in mice w
Kinetic models for nucleocytoplasmic transport of messenger RNA.: J Theor Biol. 1995 May 21;174(2):169-77. Unique Identifier : AIDSLINE MED/95371349; Schroder HC; Muller WE; Agutter PS; Abteilung fur Angewandte Molekularbiologie, Universitat Mainz,; Germany.; Much is known about the mechanism by which mRNAs cross the nuclear envelope (the translocation stage of nucleocytoplasmic transport), but far less is known about the preceding (intranuclear migration/release) and succeeding (cytoplasmic binding) stages. Therefore, existing information suffices for articulating detaile
Acquired immunodeficiency syndrome-related Kaposi's sarcoma [see comments]: Mayo Clin Proc. 1995 Sep;70(9):869-79. Unique Identifier : AIDSLINE MED/95371383; Wang CY; Schroeter AL; Su WP; Department of Dermatology, Mayo Clinic Rochester, MN 55905, USA.; OBJECTIVE: To describe Kaposi s sarcoma (KS) associated with the acquired immunodeficiency syndrome (AIDS). DESIGN: A review of AIDS-related KS (AIDS-KS), with its associated epidemiologic and etiologic characteristics, pathogenesis, clinical manifestations, histopathologic features, prognosis, and treatment, is prese
26-year-old man with HIV infection and abdominal pain.: Mayo Clin Proc. 1995 Sep;70(9):885-8. Unique Identifier : AIDSLINE MED/95371385; MacMorran WS; Badley AD; Wilson WR; Mayo Medical School, Rochester, Minnesota, USA.
Richard Ferri elected president of National AIDS Nursing Association [interview]: Mass Nurse. 1995 Feb;65(2):5. Unique Identifier : AIDSLINE MED/95371470; Ferri R
New HIV/AIDS treatment information service.: Mass Nurse. 1995 Feb;65(2):9. Unique Identifier : AIDSLINE MED/95371471
Infection control in Australia [editorial; comment]: Med J Aust. 1995 Aug 7;163(3):117-8. Unique Identifier : AIDSLINE MED/95371504; Adams TI; Harvey BM
Reporting of occupational exposures to blood-borne pathogens in Australian teaching hospitals [see comments]: Med J Aust. 1995 Aug 7;163(3):121-3. Unique Identifier : AIDSLINE MED/95371507; MacDonald MA; Elford J; Kaldor JM; National Centre in HIV Epidemiology and Clinical Research,; Faculty of Medicine, University of New South Wales, Sydney.; OBJECTIVE: To describe the reporting of occupational exposures to blood and body fluids in Australian teaching hospitals. DESIGN: Survey by questionnaire of the major teaching hospitals in Australia, December 1992. RESULTS: Completed questionnaires were received from 88% of the 69 teaching hospitals in Australia. All
HIV exposure in health care [letter]: Med J Aust. 1995 Aug 7;163(3):164-5. Unique Identifier : AIDSLINE MED/95371524; Black R
In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides.: Mol Immunol. 1995 Jun;32(9):603-12. Unique Identifier : AIDSLINE MED/95371683; Wentworth PA; Celis E; Crimi C; Stitely S; Hale L; Tsai V; Serra HM; Del Guercio MF; Livingston B; Alazard D; et al; Cytel Corporation, San Diego, CA 92121, USA.; A protocol for in vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells (PBMCs) was developed. Antigen presenting cells (APCs) consisted of Staphylococcus aureus Cowan-I (SAC-I) activated PBMCs treated with a citrate-phosphate buffer at pH 3 to release endogenous peptides bound
Race, sex, drug use, and progression of human immunodeficiency virus disease [see comments]: N Engl J Med. 1995 Sep 21;333(12):751-6. Unique Identifier : AIDSLINE MED/95371713; Chaisson RE; Keruly JC; Moore RD; Department of Medicine, Johns Hopkins University School of; Medicine, Baltimore, MD, USA.; BACKGROUND. The rates of progression of human immunodeficiency virus (HIV) infection and survival have been reported to differ among sociodemographic groups. It is unclear whether these differences reflect biologic differences or differences in access to medical care. METHODS. We measured disease progression and survi
Herpes-like DNA sequences, AIDS-related tumors, and Castleman's disease [letter; comment]: N Engl J Med. 1995 Sep 21;333(12):797-8; discussion 798-9. Unique Identifier : AIDSLINE MED/95371722; Karcher DS; Alkan S
Periorbital edema in Kaposi's sarcoma [letter; comment]: N Engl J Med. 1995 Sep 21;333(12):799-800. Unique Identifier : AIDSLINE MED/95371724; Harrison M; Tomlinson D; Stewart S
Complex partial status epilepticus accompanied by serious morbidity and mortality.: Neurology. 1995 Aug;45(8):1499-504. Unique Identifier : AIDSLINE MED/95371889; Krumholz A; Sung GY; Fisher RS; Barry E; Bergey GK; Grattan LM; Department of Neurology, University of Maryland School of; Medicine, Baltimore, USA.; Nonconvulsive status epilepticus (NCSE) accounts for approximately 20% of all status epilepticus (SE). Although convulsive SE is recognized as a medical emergency, prompt diagnosis and treatment of patients with NCSE is often not emphasized because its consequences are thought to be benign. We report 10 patients with
Erythropoietin and the anaemia of chronic disease.: Nephrol Dial Transplant. 1995;10 Suppl 2:10-7. Unique Identifier : AIDSLINE MED/95371946; Krantz SB; Haematology Division, Vanderbilt University School of Medicine,; Nashville, TN 37232-2287, USA.; The anaemia of chronic disease is the second most common anaemia in the world and is an underproduction anaemia with relatively low erythropoietin (EPO) values for the degree of the anaemia. This anaemia occurs with inflammation, infection, or malignancy and a principle question has been whether it would respond to re
Erythropoietin receptor: application in drug development.: Nephrol Dial Transplant. 1995;10 Suppl 2:28-34. Unique Identifier : AIDSLINE MED/95371948; Jolliffe LK; Middleton SA; Barbone FP; Johnson DL; McMahon FJ; Lee WH; Gruninger RH; Mulcahy LS; R. W. Johnson Pharmaceutical Research Institute, Raritan, NJ; 08869, USA.; Erythropoietin (EPO) is the primary hormone responsible for the growth and maturation of red blood cells in mammals. In contrast to many other growth factors, the specificity of EPO for mature erythroid cells has lead to its development as a safe and efficacious therapeutic, EPREX. The medical benefits of EPREX have b
Mechanisms underlying the increased susceptibility of aged mice to tuberculosis.: Nutr Rev. 1995 Apr;53(4 Pt 2):S35-8; discussion S38-40. Unique Identifier : AIDSLINE MED/95372002; Orme I; College of Veterinary Medicine and Biomedical Sciences at; Colorado State University, Fort Collins 80523, USA.
Survey cites need for HIV/AIDS education in long term care.: N J Nurse. 1995 Mar;25(2):1-2. Unique Identifier : AIDSLINE MED/95372196; Wurmser T
NJSNA Position Statement. Disclosure of HIV positive health care workers.: N J Nurse. 1995 Mar;25(2):3. Unique Identifier : AIDSLINE MED/95372197
Acquired circulating anticoagulant with anti-factor V activity in AIDS: first case report.: Nouv Rev Fr Hematol. 1995;37(2):165-9. Unique Identifier : AIDSLINE MED/95372208; Denis A; Baudeau C; Verdy E; Couderc R; Rondeau E; Sraer JD; Laboratoire d'Hematologie, Hopital Tenon, Paris, France.; An acquired circulating anticoagulant with anti-factor V activity appeared in a 29 year old AIDS patient with widespread Kaposi s sarcoma following 21 days of fresh frozen plasma therapy for haemolytic and uraemic syndrome. Residual factor V activity was very low (
Protection package.: Nurs Times. 1995 Jul 26-Aug 1;91(30):20-1. Unique Identifier : AIDSLINE MED/95372215; Payne D
Identification of receptor ligands and receptor subtypes using antagonists in a capillary electrophoresis single-cell biosensor separation system.: Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7877-81. Unique Identifier : AIDSLINE MED/95372382; Fishman HA; Orwar O; Scheller RH; Zare RN; Department of Chemistry, Stanford University, CA 94305, USA.; A capillary electrophoresis system with single-cell biosensors as a detector has been used to separate and identify ligands in complex biological samples. The power of this procedure was significantly increased by introducing antagonists that inhibited the cellular response from selected ligand-receptor interactions.
Gene therapy for long-term expression of erythropoietin in rats.: Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):8055-8. Unique Identifier : AIDSLINE MED/95372418; Osborne WR; Ramesh N; Lau S; Clowes MM; Dale DC; Clowes AW; Department of Pediatrics, University of Washington, Seattle; 98195, USA.; The injection of recombinant erythropoietin (Epo) is now widely used for long-term treatment of anemia associated with chronic renal failure, cancer, and human immunodeficiency virus infections. The ability to deliver this hormone by gene therapy rather than by repeated injections could provide substantial clinical an
[Resistance to EPO. Hyperfunction of the parathyroid glands]: Przegl Lek. 1995;52(3):86-7. Unique Identifier : AIDSLINE MED/95372568; Kokot F
[Resistance to rHuEPO]: Przegl Lek. 1995;52(3):88-9. Unique Identifier : AIDSLINE MED/95372569; Sulowicz W
[Residual risk of retrovirus transmission by transfusions]: Rev Clin Esp. 1995 Jun;195(6):418-24. Unique Identifier : AIDSLINE MED/95372685; Soriano V; Heredia A; Servicio de Enfermedades Infecciosas, Instituto de Salud Carlos; III, Madrid.
[Neuroradiological changes in a case of lumbosacral polyradiculopathy caused by cytomegalovirus in a patient with AIDS (letter)]: Rev Clin Esp. 1995 Jun;195(6):442-3. Unique Identifier : AIDSLINE MED/95372691; Miro O; Miranda-Guardiola F; Graus F; Miro JM
[Comparison of deaths in the case register of AIDS and deaths of AIDS in mortality register: Barcelona 1991-1992]: Rev Sanid Hig Publica (Madr). 1995 Jan-Feb;69(1):49-57. Unique Identifier : AIDSLINE MED/95372773; Montella i Jordana N; Ricart de Mesones I; Borrell i Thio C; Clos i Guix R; Cayla i Buqueras JA; Servicio de Informacion Sanitaria, Instituto Municipal de la; Salud de Barcelona.; BACKGROUND: To compare information on the deaths detected by the register of AIDS cases and the register of deaths due to AIDS in residents of Barcelona, with the objective to determine the differences between the two. METHODS: Mortality data were obtained from the register of AIDS cases and the mortality register dur
HIV clinical conference call series available from USPHS [news]: Tex Nurs. 1995 Feb;69(2):7. Unique Identifier : AIDSLINE MED/95372877
[Immunological research and diagnosis in gastroenterology--a review on occasion of two jubilees]: Tidsskr Nor Laegeforen. 1995 Jun 30;115(17):2067-71. Unique Identifier : AIDSLINE MED/95372888; Brandtzaeg P; Fausa O; Laboratorium for Immunhistokjemi og immunopatologi; Institutt/avdeling for patologi, Universitetet i Oslo; Rikshospitalet.; Norwegian immunological research in gastroenterology is well recognized internationally, and the European Medical Research Council Clinical Network for Gastroenterological Immunology is organized from Oslo. This development can be explained mainly by successful cooperation between clinical gastroenterology and laborat
CD8 thymocytes derived from 3,3',4,4'-tetrachlorobiphenyl-exposed fetal thymi possess killing activity.: Toxicol Appl Pharmacol. 1995 Aug;133(2):223-32. Unique Identifier : AIDSLINE MED/95372921; Lai ZW; Griem P; Gleichmann E; Esser C; Division of Immunology, Medical Institute of Environmental; Hygiene, Heinrich Heine University Dusseldorf, Germany.; 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and its congeners such as 3,3 ,4,4 -tetrachlorobiphenyl (TCB) cause immunosuppression in experimental animals and possibly in humans. In previous studies we found that exposure of murine fetal thymic organ cultures (FTOCs) to TCDD or TCB reduced the proliferative capacity of
[Nocardiosis in HIV patients]: Ugeskr Laeger. 1995 Jul 31;157(31):4358-60. Unique Identifier : AIDSLINE MED/95373013; Meyer CN; Epidemiafdeling M, Rigshospitalet, Kobenhavn.; Two cases of nocardiosis, an uncommon disease in HIV patients, are presented. Considerations concerning diagnosis, clinical pictures, treatment and prophylaxis are discussed. Because of profound morbidity and mortality, the possibility of Nocardia infection should be suspected in cases of pulmonary infection where mor
Induction of humoral and cellular immune responses to the human immunodeficiency type 1 virus in nonhuman primates by in vivo DNA inoculation.: Virology. 1995 Aug 1;211(1):102-12. Unique Identifier : AIDSLINE MED/95373127; Wang B; Boyer J; Srikantan V; Ugen K; Gilbert L; Phan C; Dang K; Merva M; Agadjanyan MG; Newman M; et al; Apollon, Inc., Malvern, Pennsylvania 19355, USA.; DNA inoculation has the potential to produce antigens in a native as well as a host-customized form for presentation to the immune system. As such this technology may have relevance for vaccine/immune therapeutic strategies for a variety of infectious pathogens. In rodents in vivo inoculation of plasmid expression vec
Infection and replication of Tat- human immunodeficiency viruses: genetic analyses of LTR and tat mutations in primary and long-term human lymphoid cells.: Virology. 1995 Aug 1;211(1):157-69. Unique Identifier : AIDSLINE MED/95373132; Chang LJ; Zhang C; Department of Medical Microbiology and Immunology, University of; Alberta, Edmonton, Canada.; Tat is an essential regulatory protein for the replication of human immunodeficiency virus (HIV). Mutations in the tat gene have been shown to block HIV replication in human T cells. Several studies have established that Tat releases an elongation block to the transcription of HIV long terminal repeat (LTR); however,
Sequence distances between env genes of HIV-1 from individuals infected from the same source: implications for the investigation of possible transmission events.: Virology. 1995 Aug 1;211(1):198-203. Unique Identifier : AIDSLINE GENBANK/U23138; Arnold C; Balfe P; Clewley JP; Molecular Biology Unit, Central Public Health Laboratory, London,; United Kingdom.; Previously described transmission studies have shown that HIV strains isolated from individuals infected from a common source are more homogeneous than HIV strains isolated from individuals with unrelated infections. This has been the basis, in at least four instances, for deciding whether apparently epidemiologically
Virofection: a one-step procedure for using replication-defective retrovirus vectors.: Virology. 1995 Aug 1;211(1):234-40. Unique Identifier : AIDSLINE MED/95373141; Flamant F; Samarut J; Laboratoire de Biologie INRA-CNRS Ecole Normale Superieure de; Lyon, France.; Virofection is a simple new way to use replication-defective vectors. It consists of the cotransfection of two plasmids: one plasmid bearing the genome of the replication-defective retrovirus vector and a second helper plasmid expressing the gag, pol, and env retrovirus sequences. It provides stable integration into t
Cross-reactive cytotoxic T lymphocytes induced by V3 loop synthetic peptides from different strains of human immunodeficiency virus type 1.: Virology. 1995 Aug 1;211(1):261-7. Unique Identifier : AIDSLINE MED/95373144; Casement KS; Nehete PN; Arlinghaus RB; Sastry KJ; Department of Molecular Pathology, University of Texas M. D.; Anderson Cancer Center, Houston 77030, USA.; Recent efforts at understanding the immune response generated against human immunodeficiency virus (HIV) infection have focused on cytotoxic T lymphocyte (CTL)-mediated recognition of HIV antigens. CTLs are a major immune defense mechanism and are necessary for the recovery of many viral infections. We have previously
Analysis of cysteine mutations on the transmembrane protein of Moloney murine leukemia virus.: Virology. 1995 Aug 1;211(1):285-9. Unique Identifier : AIDSLINE MED/95373147; Thomas A; Roth MJ; Department of Biochemistry, University of Medicine and Dentistry; of New Jersey, Robert Wood Johnson Medical School, Piscataway; 08854, USA.; Earlier studies of murine leukemia viruses (MuLVs) have reported that a percentage of surface protein (SU) remains covalently associated with transmembrane protein (TM) through formation of disulfide bonds. Among MuLVs, there are three conserved cysteine residues within the extracellular domain of TM. These cysteine r
The activation domain of simian immunodeficiency virus SIVmac239 Rev protein is structurally and functionally analogous to the HIV-1 Rev activation domain.: Virology. 1995 Aug 1;211(1):285-9. Unique Identifier : AIDSLINE MED/95373148; Berchtold S; Hornung U; Aepinus C; Institut fur Klinische und Molekulare Virologie, Universitat; Erlangen-Nurnberg, Federal Republic of Germany.; The Rev proteins of primate immunodeficiency viruses are essential transactivators for the switch from early to late phase in the viral replication cycle. By mutational analysis, a putative activation domain (AD) has been assigned to the carboxy-terminus. This leucine-rich stretch of amino acids proved to be essential
Virologic and serologic characteristics of a natural chimpanzee lentivirus infection.: Virology. 1995 Aug 1;211(1):312-5. Unique Identifier : AIDSLINE MED/95373152; Peeters M; Janssens W; Vanden Haesevelde M; Fransen K; Willems B; Heyndrickx L; Kestens L; Piot P; Van der Groen G; Heeney J; World Health Collaborating Center on AIDS, Department of; Infection and Immunity, Institute of Tropical Medicine, Antwerp,; Belgium.; This study set out to characterize the unique features of natural lentivirus infection in chimpanzees over time. The virologic and serologic characteristics of this infection were followed longitudinally in a naturally infected chimpanzee together with a small cohort of experimentally HIV-1-infected chimpanzees. The s
CTL escape viral variants. II. Biologic activity in vivo.: Virology. 1995 Aug 20;211(2):443-50. Unique Identifier : AIDSLINE MED/95373177; Lewicki HA; Von Herrath MG; Evans CF; Whitton JL; Oldstone MB; Department of Neuropharmacology, Scripps Research Institute, La; Jolla, California 92037, USA.; The proteins of lymphocytic choriomeningitis virus (LCMV) contain only three known peptide regions that are processed and then held in place by the MHC class I H-2b (Db) glycoprotein on the cell s surface for recognition by LCMV-specific Db-restricted cytotoxic T lymphocytes (CTL). These peptides are from the glycopro
The human immunodeficiency virus tat gene enhances replication of human herpesvirus-6.: Virology. 1995 Aug 20;211(2):544-53. Unique Identifier : AIDSLINE MED/95373187; Sieczkowski L; Chandran B; Wood C; Department of Neurology, University of Miami School of Medicine,; Florida 33101, USA.; Human herpesvirus-6 (HHV-6) can enhance the cytopathic effects of human immunodeficiency virus type 1 (HIV-1) in cells doubly infected by HIV-1 and HHV-6. HHV-6 enhances transcription of the HIV-1 long terminal repeat, and several HHV-6 trans-activator genes have been identified. Since HIV-1 and HHV-6 have similar cel
Herpes zoster in children with bone marrow transplantation: Report from a single institution.: Acta Paediatr Jpn. 1995 Jun;37(3):302-7. Unique Identifier : AIDSLINE MED/95373314; Nakayama H; Okamura J; Ohga S; Miyazaki C; Matsuzaki A; Ikuno Y; Ueda K; Tasaka H; Section of Pediatrics, National Kyushu Cancer Center, Fukuoka,; Japan.; Herpes zoster (HZ) has been often observed after bone marrow transplantation (BMT) in childhood. The occurrence of HZ was reviewed in children who received BMT. The clinical features of HZ were reviewed in 44 children who underwent BMT at Kyushu Cancer Center. Among the 35 recipients with a history of varicella before
Apoptosis in human immunodeficiency virus-associated nephropathy.: Am J Kidney Dis. 1995 Aug;26(2):286-91. Unique Identifier : AIDSLINE MED/95373477; Bodi I; Abraham AA; Kimmel PL; Department of Pathology, George Washington University Medical; Center, Washington, D.C. 20037, USA.; Focal segmental glomerulosclerosis associated with human immunodeficiency virus nephropathy (HIVFGS) involves glomeruli, tubules, and interstitium. Its pathogenesis is unknown, but HIV peptides may be critical in its development. Human immunodeficiency virus peptides and peptide-antibody complexes are immunomodulatory
Pattern of glomerular involvement in human immunodeficiency virus-infected patients: an Italian study.: Am J Kidney Dis. 1995 Sep;26(3):446-53. Unique Identifier : AIDSLINE MED/95373498; Casanova S; Mazzucco G; Barbiano di Belgiojoso G; Motta M; Boldorini R; Genderini A; Monga G; Laboratorio di Microscopia Elettronica, Ospedale M. Malpighi,; Bologna, Italy.; Renal biopsy specimens from 26 adult human immunodeficiency virus (HIV)-infected patients with glomerular involvement were reviewed from the files of three hospital pathology services in Northern Italy . All the patients were Italian and most (19 of 26 patients) were intravenous drug
Decreases of CD4- and CD8-positive T lymphocytes in retired chromate workers.: Am J Ind Med. 1995 Jun;27(6):877-82. Unique Identifier : AIDSLINE MED/95373527; Tanigawa T; Araki S; Araki T; Minato N; Yokoyama K; Department of Public Health, Faculty of Medicine, University of; Tokyo, Japan.; To investigate the effects of chromates on the human immune system, we measured total T lymphocytes and their two major subpopulations (CD4+ and CD8+ T lymphocytes) in the peripheral blood of 19 retired male workers who had been exposed to chromate at a chemical plant. The results indicated that both CD4+ and CD8+ T l
Postnatal transmission of human immunodeficiency virus type 1: the breast-feeding dilemma.: Am J Obstet Gynecol. 1995 Aug;173(2):483-7. Unique Identifier : AIDSLINE MED/95373573; Van de Perre P; Rwandan-Belgian Medical Cooperation, Brussels, Belgium.; Human milk has been considered only recently as a source of transmission for the human immunodeficiency virus. The estimated postnatal transmission rate from mothers who acquired human immunodeficiency virus infection while lactating is 26% (95% confidence interval 13% to 39%) and may be in the range of 8% to 18% from
The relationship of the duration of ruptured membranes to vertical transmission of human immunodeficiency virus.: Am J Obstet Gynecol. 1995 Aug;173(2):585-9. Unique Identifier : AIDSLINE MED/95373589; Minkoff H; Burns DN; Landesman S; Youchah J; Goedert JJ; Nugent RP; Muenz LR; Willoughby AD; Department of Obstetrics and Gynecology, State University of New; York Health Science Center at Brooklyn 11203, USA.; OBJECTIVE: Intrapartum events may play a role in determining the likelihood of vertical transmission of human immunodeficiency virus-1. Timing and duration of rupture of membranes have been shown to modify transmission risk of other organisms but have not been examined for human immunodeficiency virus. This study was
[Endemic of AIDS in Spain. Commentaries on official statistics]: An R Acad Nac Med (Madr). 1995;112(1):163-75; dicussion 175-6. Unique Identifier : AIDSLINE MED/95373641; Garcia Perez A
[Increase of tuberculosis and coinfection with AIDS]: An R Acad Nac Med (Madr). 1995;112(1):21-41; discussion 41-2. Unique Identifier : AIDSLINE MED/95373643; Del Rey Calero J
The critical care of those with AIDS.: Am Nurse. 1995 Apr-May;27(3):30. Unique Identifier : AIDSLINE MED/95373761; Himali U
Grants are foundation of ANA's work on HIV/AIDS issues.: Am Nurse. 1995 Apr-May;27(3):30, 38. Unique Identifier : AIDSLINE MED/95373762; Veroneau P; Campbell K
Anti-regulatory fast track in Congress could derail RN's workplace protections.: Am Nurse. 1995 Apr-May;27(3):38. Unique Identifier : AIDSLINE MED/95373763; Himali U
Construction of a superantigen through a structural modification of an inactive protein.: Ann N Y Acad Sci. 1995 Jul 7;756:117-9. Unique Identifier : AIDSLINE MED/95373773; Imberti L; Sottini A; Quiros E; Mattioli S; Prati E; Albertini A; Primi D; Conbiotec and III Laboratorio Analisi, Spedali Civili, Brescia,; Italy.
Expansions of V alpha 12 CD8+ T-cells in rheumatoid arthritis.: Ann N Y Acad Sci. 1995 Jul 7;756:130-7. Unique Identifier : AIDSLINE MED/95373777; Behar SM; Roy C; Brenner MB; Department of Rheumatology and Immunology, Brigham and Women's; Hospital, Boston, Massachusetts 02115, USA.
T-cell receptor V beta gene utilization in rheumatoid arthritis.: Ann N Y Acad Sci. 1995 Jul 7;756:159-72. Unique Identifier : AIDSLINE MED/95373780; Jenkins RN; McGinnis DE; Harold C. Simmons Arthritis Research Center, University of Texas; Southwestern Medical School, Dallas 75235, USA.
Analysis of the peripheral blood T-cell receptor repertoire in monozygotic twins discordant for rheumatoid arthritis.: Ann N Y Acad Sci. 1995 Jul 7;756:176-8. Unique Identifier : AIDSLINE MED/95373782; Gulwani-Akolkar B; Akolkar PN; Gregersen PK; Silver J; Department of Medicine, North Shore University Hospital/Cornell; University Medical College, Manhasset, New York 11030, USA.
CDR3 length restriction of T-cell receptor beta chains in CD8+ T-cells of rheumatoid arthritis patients.: Ann N Y Acad Sci. 1995 Jul 7;756:179-82. Unique Identifier : AIDSLINE MED/95373783; Hingorani R; Monteiro J; Pergolizzi R; Furie R; Chartash E; Gregersen PK; Department of Medicine, North Shore University Hospital/Cornell; University Medical Center, Manhasset, New York 11030, USA.
Unstimulated rheumatoid synovial T-cells have a consistent V beta gene bias when compared to peripheral blood T-cells.: Ann N Y Acad Sci. 1995 Jul 7;756:186-9. Unique Identifier : AIDSLINE MED/95373785; Cooper SM; Roessner KD; Naito-Hoopes M; Dobbs C; Nicklas JA; Howard DB; Gaur LK; Budd RC; Department of Medicine, University of Vermont, Burlington 05405,; USA.
Oligoclonality in the CD8+ T-cell population. Analysis using a multiplex PCR assay for CDR3 length.: Ann N Y Acad Sci. 1995 Jul 7;756:19-27. Unique Identifier : AIDSLINE MED/95373786; Gregersen PK; Hingorani R; Monteiro J; Department of Medicine, North Shore University Hospital,; Manhasset, New York 11030, USA.
The influence of genetics, environment, and disease state on the human T-cell receptor repertoire.: Ann N Y Acad Sci. 1995 Jul 7;756:28-52. Unique Identifier : AIDSLINE MED/95373805; Silver J; Gulwani-Akolkar B; Akolkar PN; Department of Medicine, North Shore University Hospital/Cornell; University Medical College, Manhasset, New York 11030, USA.
Clonal dominance of CD8+ T-cell in multiple sclerosis.: Ann N Y Acad Sci. 1995 Jul 7;756:310-2. Unique Identifier : AIDSLINE MED/95373810; Monteiro J; Hingorani R; Pergolizzi R; Apatoff B; Gregersen PK; Department of Medicine, North Shore University Hospital, Cornell; University Medical Center, Manhasset, New York 10030, USA.
CD8+ T-cells in psoriatic lesions preferentially use T-cell receptors V beta 3 and/or V beta 13.1 genes.: Ann N Y Acad Sci. 1995 Jul 7;756:370-81. Unique Identifier : AIDSLINE MED/95373822; Chang JC; Smith LR; Froning KJ; Schwabe BJ; Laxer JA; Caralli LL; Kurkland HH; Karasek MA; Wilkinson DI; Carlo DJ; et al; Immune Response Corporation, Carlsbad, California 92008, USA.; Restricted T-cell receptor V beta gene use in animal models of autoimmune disease has led to the development of strategies to treat autoimmune disease by targeting the T-cell receptors of the pathogenic T-cells. Restricted T-cell receptor gene use has been noted in human autoimmune diseases such as rheumatoid arthriti
V beta-specific activation of T-cells by the HIV glycoprotein gp160.: Ann N Y Acad Sci. 1995 Jul 7;756:447-9. Unique Identifier : AIDSLINE MED/95373840; Akolkar PN; Gulwani-Akolkar B; Chirmule N; Pahwa S; Kalyanaraman VS; Pergolizzi R; Macphail S; Silver J; Department of Medicine, North Shore University Hospital/Cornell; University Medical College, Manhasset, New York 11030, USA.
Preferential expression of the human V beta 7.1 gene segment on CD8+ peripheral blood lymphocytes.: Ann N Y Acad Sci. 1995 Jul 7;756:94-5. Unique Identifier : AIDSLINE MED/95373850; Callan MF; Gillespie GM; Reyburn HT; Moss PA; Bell JI; McMichael AJ; Institute of Molecular Medicine, John Radcliffe Hospital,; Headington, Oxford, United Kingdom.
Variability in CD8+ T-cell oligoclonality patterns in monozygotic twins.: Ann N Y Acad Sci. 1995 Jul 7;756:96-8. Unique Identifier : AIDSLINE MED/95373851; Monteiro J; Hingorani R; Choi IH; Pergolizzi R; Silver J; Gregersen PK; Department of Medicine, North Shore University Hospital,; Manhasset, New York 11030, USA.
Interferon resistance is independent from copy numbers in benign HPV-induced lesions.: Anticancer Res. 1995 May-Jun;15(3):1003-6. Unique Identifier : AIDSLINE MED/95373888; Arany I; Nagamani K; Tyring SK; Department of Microbiology and Immunology, University of Texas; Medical Branch, Galveston 77555-1019, USA.; Interferons (IFNs) are successfully used in treatment of different human papillomavirus (HPV)-related diseases, such as condyloma acuminatum. Unresponsiveness can be seen in a number of patients which is related to a differential expression of early (E7) and late (L1) viral genes, according to our preliminary studies
Esophago-airway fistula in AIDS.: Ann Thorac Surg. 1995 Aug;60(2):440-2. Unique Identifier : AIDSLINE MED/95374099; Temes RT; Wong RS; Davis M; Kessler RM; Wernly JA; Department of Surgery, University of New Mexico School of; Medicine, Albuquerque 87131, USA.; Fistula formation between the esophagus and airway in acquired immunodeficiency syndrome is extremely unusual. We report 2 cases, the first in a patient who did not undergo definitive surgical management and died shortly after diagnosis. The second patient was managed successfully for 5 months by insertion of a Celest
[Malignant tumoral lymphoma of the heart in human immunodeficiency virus infection: diagnosis by echocardiography]: Arch Mal Coeur Vaiss. 1995 Apr;88(4):507-10. Unique Identifier : AIDSLINE MED/95374256; Denis J; Hery B; Crepin V; Guillemot L; Guerzider P; Service de cardiologie, centre hospitalier general,; Saint-Nazaire.; Non-Hodgkin s lymphoma is common in patients with human immuno-deficiency virus infection, but an intracardiac localisation is rare. In this case, the malignant lymphoma presented with a degradation of the patient s condition and signs of right-sided cardiac failure. Echocardiography showed a polylobed mass invading t
Primary cutaneous angiotropic large-cell lymphoma in a patient with acquired immunodeficiency syndrome.: Arch Pathol Lab Med. 1995 Aug;119(8):757-9. Unique Identifier : AIDSLINE MED/95374326; Dunphy CH; Department of Pathology, St Louis University Health Sciences; Center, MO, USA.; Patients with acquired immunodeficiency syndrome are at increased risk of developing malignant lymphoma, particularly of the large noncleaved, immunoblastic, and small noncleaved cell types. Angiotropic large-cell lymphoma, a relatively rare high-grade lymphoma, has not previously been described in the setting of acqu
Phylogenetic analysis of the long terminal repeat of feline immunodeficiency viruses from Japan, Argentina and Australia.: Arch Virol. 1995;140(1):41-52. Unique Identifier : AIDSLINE GENBANK/D31941; Yamada H; Miyazawa T; Tomonaga K; Kawaguchi Y; Maeda K; Castellano MC; Kai C; Tohya Y; Mikami T; Department of Veterinary Microbiology, Faculty of Agriculture,; University of Tokyo, Japan.; The nucleotide sequences of the long terminal repeat of five Japanese, five Argentine and three Australian isolates of feline immunodeficiency virus (FIV) were determined and compared with those of isolates previously described. The results revealed that the Japanese isolates were found to cluster with nucleotide sequ
Specific T-cell response correlates with resistance of genetic heterogeneous mouse populations to mouse hepatitis virus 3 infection.: Arch Virol. 1995;140(7):1235-45. Unique Identifier : AIDSLINE MED/95374351; Vassao RC; Cabrera WH; Ibanez OC; Pereira CA; Laboratorio de Imunologia Viral, Instituto Butantan, Sao Paulo,; Brazil.; In a recently published study [Vassao RC, Mello IGC, Pereira CA (1994) Arch Virol 137: 277-288] we have shown that the genetically selected high antibody responder mice (HIII) are susceptible and the low antibody responder counterparts (LIII) are resistant to death induced by experimental infection with mouse hepatiti
Immunoelectron microscopic study of HTLV-II-producing cells with an anti-envelope gp46 monoclonal antibody.: Arch Virol. 1995;140(7):1291-5. Unique Identifier : AIDSLINE MED/95374357; Ohara N; Hayashi K; Miyamoto K; Takahashi K; Ohtsuki Y; Akagi T; Second Department of Pathology, Okayama University Medical; School, Japan.; We observed expression of envelope gp46 protein on an HTLV-II-producing T-cell line (Mo) cells by an immunoelectron microscopical method using a monoclonal antibody against HTLV-II gp46. gp46 reactivity was observed on virus-like particles, extracellular vesicles, cell membrane, and partially in nuclear membrane and e
A 200-amino acid ATPase module in search of a basic function.: Bioessays. 1995 Jul;17(7):639-50. Unique Identifier : AIDSLINE MED/95374488; Confalonieri F; Duguet M; Institut de Genetique et Microbiologie, CNRS-Universite Paris,; Orsay, France.; A fast growing family of ATPases has recently been highlighted. It was named the AAA family, for ATPases Associated to a variety of cellular Activities. The key feature of the family is a highly conserved module of 230 amino acids present in one or two copies in each protein. Despite extensive sequence conservation, t
RNA signals for translation frameshift: influence of stem size and slippery sequence.: Biochem Biophys Res Commun. 1995 Aug 15;213(2):575-82. Unique Identifier : AIDSLINE MED/95374520; Honda A; Nakamura T; Nishimura S; Banyu Tsukuba Research Institute, Merck Research Laboratories,; Japan.; The pol gene of HIV-1 is expressed as a fusion protein with the upstream gag gene product after -1 ribosomal frameshifting. To get insights into the sequence requirements for the slippery heptanucleotide, generally present at the frameshift junction, and the downstream stem-loop structure, we prepared, starting from t
Extra-nuclear location of histones in activated human peripheral blood lymphocytes and cultured T-cells.: Biochem Pharmacol. 1995 Jul 31;50(3):299-309. Unique Identifier : AIDSLINE MED/95374543; Watson K; Edwards RJ; Shaunak S; Parmelee DC; Sarraf C; Gooderham NJ; Davies DS; Department of Clinical Pharmacology, Royal Postgraduate Medical; School, London, U.K.; Dextrin-2-sulphate (D2S) is a sulphated polysaccharide which inhibits human immunodeficiency virus type 1 infection of T-cells by binding to the cell surface. During our investigations of the nature of this interaction, a cell membrane fraction was prepared by ultracentrifugation from the T-cell line, HPB-ALL. Separat
Prevention and treatment of Pneumocystis carinii pneumonia in patients infected with HIV [published erratum appears in Drug Ther Bull 1994 Mar 17;32(3):24]: Drug Ther Bull. 1994 Feb 17;32(2):12-5. Unique Identifier : AIDSLINE MED/95361721; The fungus Pneumocystis carinii, which rarely if ever causes illness in otherwise healthy people, can cause potentially fatal pneumonia in patients with defects of cell-mediated immunity resulting, for example, from chemotherapy or immunosuppression after organ transplantation. P. carinii pneumonia also occurs in up t
Clinical problem-solving: we blew it [letter; comment]: N Engl J Med. 1995 Aug 24;333(8):520; discussion 521. Unique Identifier : AIDSLINE MED/95349667; Barritt AS 3rd
Immune status of newborns in perinatal chlamydial infection.: Am J Reprod Immunol. 1995 Jan;33(1):94-6. Unique Identifier : AIDSLINE MED/95344472; Pirogova VI; Vinograd NA; Zhemela EM; Chegrinec NA; Department of Obstetrics, Gynecology, and Perinatology, Medical; Institute, Lviv, Ukraine.; PROBLEM: Thirty newborns, delivered by mothers with urogenital chlamydiosis, diagnosed on the 35th-36th weeks of gestation, and 10 newborns of healthy mothers were studied immunologically. CD3 (T-lymphocytes), CD19 (B-lymphocytes), CD4 (T-helpers-inductors), CD8 (T-suppressor-cytotoxic), T-lymphocyte response to PHA,
Culturally sensitive AIDS education and perceived AIDS risk knowledge: reaching the know-it-all teenager.: AIDS Educ Prev. 1995 Apr;7(2):134-44. Unique Identifier : AIDSLINE MED/95344905; Stevenson HC; Gay KM; Josar L; University of Pennsylvania, Graduate School of Education,; Psychology in Education Division, Philadelphia 19104-6216, USA.; Video education is the most popular and effective medium for informing the adolescent population. This study investigated the impact of a culturally relevant HIV/AIDS video education. One hundred and ninety-four African-American teenagers were assigned to either a culturally sensitive or culturally dissimilar video ed
[Heterogeneity of antimicrosomal autoantibodies in chronic hepatitis C virus infection and delta hepatitis]: Ann Ital Med Int. 1995 Apr-Jun;10(2):93-7. Unique Identifier : AIDSLINE MED/95344920; Durazzo M; Costa C; Schmidt E; Loges S; Scaglione L; Touscoz AG; Smedile A; Manns MP; Rizzetto M; Pagano G; Istituto di Medicina Interna, Universita degli Studi di Torino.; Microsomal antigen autoantibodies are typical of type 2 autoimmune hepatitis, and a strong association with chronic hepatitis C virus (HCV) infection has been reported in certain geographical areas. These autoantibodies have been denominated LKM-1 to differentiate them from those associated with thienylic acid-induced
[To treat or not to treat: the indications and contraindications for the use of interferon in chronic viral hepatitis]: Minerva Gastroenterol Dietol. 1995 Mar;41(1):89-96. Unique Identifier : AIDSLINE MED/95345255; Piccinino F; Piccinino R; Scolastico C; Istituto di Clinica Malattie Tropicali e Subtropicali, Facolta; di Medicina e Chirurgia, Seconda Universita degli Studi, Napoli.
Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages.: Blood. 1995 Aug 1;86(3):1184-95. Unique Identifier : AIDSLINE MED/95345471; Weinberg JB; Misukonis MA; Shami PJ; Mason SN; Sauls DL; Dittman WA; Wood ER; Smith GK; McDonald B; Bachus KE; et al; Department of Medicine, Veterans Affairs, Medical Center, Durham,; NC.; Nitric oxide (NO) is produced by numerous different cell types, and it is an important regulator and mediator of many processes including smooth muscle relaxation, neurotransmission, and murine macrophage-mediated cytotoxicity for microbes and tumor cells. Although murine macrophages produce NO readily after activatio
Molecular approaches to AIDS vaccine development using baculovirus expression vectors.: Methods Mol Biol. 1995;39:295-315. Unique Identifier : AIDSLINE MED/95345942; Kang CY; Department of Microbiology and Immunology, University of Ottawa,; Ontario, Canada.
Antiviral therapy for human immunodeficiency virus infections.: Clin Microbiol Rev. 1995 Apr;8(2):200-39. Unique Identifier : AIDSLINE MED/95346869; De Clercq E; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.; Depending on the stage of their intervention with the viral replicative cycle, human immunodeficiency virus inhibitors could be divided into the following groups: (i) adsorption inhibitors (i.e., CD4 constructs, polysulfates, polysulfonates, polycarboxylates, and polyoxometalates), (ii) fusion inhibitors (i.e., plant
Common variable immunodeficiency (CVID) and MxA-protein expression in blood leucocytes.: Clin Exp Immunol. 1995 Jul;101(1):89-93. Unique Identifier : AIDSLINE MED/95347088; Rump JA; Jakschiess D; Walke