Methods for detection of an intestinal secretory immunoglobulin A response to Candida spp. and their preliminary application in human immunodeficiency virus-infected patients with chronic diarrhea. NLM AIDSLINE Important note: Information in this article was accurate in 1995. The state of the art may have changed since the publication date.

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Methods for detection of an intestinal secretory immunoglobulin A response to Candida spp. and their preliminary application in human immunodeficiency virus-infected patients with chronic diarrhea.

Clin Diagn Lab Immunol. 1995 Mar;2(2):246-8. Unique Identifier : AIDSLINE MED/95211646
Scerpella EG; Gould SS; Mathewson JJ; DuPont HL; Center for Infectious Diseases, University of Texas Medical; School, Houston.

Abstract: Six of 11 human immunodeficiency virus (HIV)-infected patients with chronic diarrhea, shedding only Candida spp. in their stools, elicited a Candida-specific secretory immunoglobulin A response. Similar responses were identified in only 1 of 10 HIV-positive patients with chronic diarrhea but without Candida spp. and in none of 10 HIV-negative subjects without diarrhea. Candida spp. may play a role in the etiology of chronic diarrhea associated with HIV infection.
Keywords: Antigens, Fungal AIDS-Related Opportunistic Infections/*IMMUNOLOGY/MICROBIOLOGY Blotting, Western Candidiasis/*IMMUNOLOGY/VIROLOGY Chronic Disease Diarrhea/*IMMUNOLOGY/MICROBIOLOGY/VIROLOGY Electrophoresis, Polyacrylamide Gel Enzyme-Linked Immunosorbent Assay Feces/CHEMISTRY/MICROBIOLOGY Human HIV Infections/*IMMUNOLOGY/MICROBIOLOGY IgA, Secretory/*ANALYSIS/*BIOSYNTHESIS Intestinal Mucosa/*IMMUNOLOGY/*SECRETION Sodium Dodecyl Sulfate JOURNAL ARTICLEKWDantigens,fungalaids-relatedopportunisticinfections/KWDimmunology/microbiologyblotting,westerncandidiasis/KWDimmunology/virologychronicdiseasediarrhea/KWDimmunology/microbiology/virologyelectrophoresis,polyacrylamidegelenzyme-linkedimmunosorbentassayfeces/chemistry/microbiologyhumanhivinfections/KWDimmunology/microbiologyiga,secretory/KWDanalysis/KWDbiosynthesisintestinalmucosa/KWDimmunology/KWDsecretionsodiumdodecylsulfatejournalarticle
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M9570892

Copyright © 1995 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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