Trends in primary cerebral lymphoma. NLM AIDSLINE Important note: Information in this article was accurate in 1995. The state of the art may have changed since the publication date.

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Trends in primary cerebral lymphoma.

Br J Cancer. 1994 Oct;70(4):716-8. Unique Identifier : AIDSLINE MED/95001365
Lutz JM; Coleman MP; Thames Cancer Registry, Sutton, Surrey, UK.


Abstract: Primary non-Hodgkin lymphoma of the brain is rare, representing only 1% of all non-Hodgkin lymphomas (NHLs), but its incidence has been increasing rapidly in south-east England since 1985. Among 17,322 cases of NHL registered during the 18 year period 1973-90, there were 210 cases of primary cerebral NHL, of which 179 (86%) were diagnosed in the last third of this period, 1985-90. This increase in cerebral lymphoma is not adequately explained by improvements in the precision of diagnosis or by changes in disease coding or cancer registration practice. While there has also been a rapid increase in Kaposi sarcoma, neither immunosuppression acquired through HIV infection nor the overall trend in non-Hodgkin lymphoma can satisfactorily explain the recent increase in cerebral lymphoma, which affects all ages and both sexes similarly. Other possible causes for a true increase in cerebral lymphoma should be sought.
Keywords: Adolescence Adult Age Factors Aged Brain Neoplasms/*EPIDEMIOLOGY Child Child, Preschool England/EPIDEMIOLOGY Epidemiology/TRENDS Female Human HIV Infections/EPIDEMIOLOGY Incidence Infant Infant, Newborn Lymphoma, Non-Hodgkin's/*EPIDEMIOLOGY Male Middle Age Wales/EPIDEMIOLOGY JOURNAL ARTICLEKWDadolescenceadultagefactorsagedbrainneoplasms/KWDepidemiologychildchild,preschoolengland/epidemiologyepidemiology/trendsfemalehumanhivinfections/epidemiologyincidenceinfantinfant,newbornlymphoma,non-hodgkin's/KWDepidemiologymalemiddleagewales/epidemiologyjournalarticle
950130
M9510823

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