Idiopathic CD4+ lymphocytopenia associated with chronic pruritic papules. NLM AIDSLINE Important note: Information in this article was accurate in 1995. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Idiopathic CD4+ lymphocytopenia associated with chronic pruritic papules.

Br J Dermatol. 1994 Sep;131(3):371-5. Unique Identifier : AIDSLINE MED/95001458
Wakeel RA; Urbaniak SJ; Armstrong SS; Sewell HF; Herriot R; Kernohan N; White MI; Department of Dermatology, Aberdeen Royal Hospitals NHS Trust,; U.K.

Abstract: This is a case report and family study of a 65-year-old man with chronic prurigo lesions, in whom we demonstrated a selective deficiency of circulating T-helper/inducer lymphocytes (CD4+), in the absence of any apparent predisposing disease. He is seronegative for human immunodeficiency virus (HIV types 1 and 2) and human T-cell lymphotropic virus (HTLV-I and HTLV-II), and fulfils the criteria for the syndrome of idiopathic CD4+ T lymphocytopenia. He has an atopic diathesis, has had a severe adult chickenpox infection, chronic staphylococcal infections, tinea pedis and recalcitrant warts. He has also suffered from respiratory infections, for which no specific aetiological agent has been identified. His peripheral total lymphocyte count has been persistently abnormal since it was first measured in 1969. He has a marked CD4+ T-cell lymphocytopenia. His son, who does not have any skin disorder, has a low CD4+ T-cell count.
Keywords: Adult Aged Case Report Chronic Disease Disease Susceptibility Family Female Human HIV Seronegativity Male Middle Age Prurigo/*COMPLICATIONS/PATHOLOGY T-Lymphocytopenia, Idiopathic CD4-Positive/*COMPLICATIONS JOURNAL ARTICLEKWDadultagedcasereportchronicdiseasediseasesusceptibilityfamilyfemalehumanhivseronegativitymalemiddleageprurigo/KWDcomplications/pathologyt-lymphocytopenia,idiopathiccd4-positive/KWDcomplicationsjournalarticle
950130
M9510815

Copyright © 1995 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1995. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1995. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .