Bacterial and protozoal infections in genetically disrupted mice. NLM AIDSLINE Important note: Information in this article was accurate in 1995. The state of the art may have changed since the publication date.

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Bacterial and protozoal infections in genetically disrupted mice.

Curr Opin Immunol. 1994 Aug;6(4):518-25. Unique Identifier : AIDSLINE MED/95032850
Kaufmann SH; Department of Immunology, University of Ulm, Germany.

Abstract: Immune gene knock-out mice have provided challenging new opportunities for scientists interested in infection and immunity. This novel experimental approach has made it possible to gain deeper insights into the mechanisms that are operative in defence against, and the pathology of, infectious disease. It has allowed the identification not only of vital immune elements, but also of compensatory mechanisms and of novel cells that are still uncharacterized or of uncertain function.
Keywords: Animal Bacterial Infections/*IMMUNOLOGY Cytokines/IMMUNOLOGY CD4-Positive T-Lymphocytes/IMMUNOLOGY CD8-Positive T-Lymphocytes/IMMUNOLOGY Genetic Engineering Histocompatibility Antigens/IMMUNOLOGY Immunity Mice Mice, Knockout Protozoan Infections/*IMMUNOLOGY Support, Non-U.S. Gov't T-Lymphocytes/IMMUNOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIALKWDanimalbacterialinfections/KWDimmunologycytokines/immunologycd4-positivet-lymphocytes/immunologycd8-positivet-lymphocytes/immunologygeneticengineeringhistocompatibilityantigens/immunologyimmunitymicemice,knockoutprotozoaninfections/KWDimmunologysupport,non-uKWDsKWDgov'tt-lymphocytes/immunologyjournalarticlereviewreview,tutorial
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M9521027

Copyright © 1995 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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