Potential therapy for painful neuropathy. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023. NLM AIDSLINE Important note: Information in this article was accurate in 1995. The state of the art may have changed since the publication date.

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Potential therapy for painful neuropathy. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.

PI Perspect. 1995 May;(no 16):11. Unique Identifier : AIDSLINE AIDS/95700461
Lein B

Abstract: Genentech has agreed to supply nerve growth factor (NGF), a potential treatment for HIV-associated peripheral neuropathy, for an AIDS Clinical Trials Group (ACTG) study, ACTG 291. The NGF study is important since there are no therapies for peripheral neuropathy which target the underlying cause of neuropathy, nerve damage. All currently available options treat the symptoms of pain associated with peripheral neuropathy, not the cause, and neuropathy in HIV can have many different causes. NGF may help repair nerve damage caused by HIV-infection, especially small nerve damage.
Keywords: Acupuncture Amitriptyline/THERAPEUTIC USE Human HIV Infections/*COMPLICATIONS Mexiletine/THERAPEUTIC USE Nerve Growth Factors/*THERAPEUTIC USE Pain/COMPLICATIONS/*THERAPY Peripheral Nervous System Diseases/COMPLICATIONS/*THERAPY NEWSLETTER ARTICLEKWDacupunctureamitriptyline/therapeuticusehumanhivinfections/KWDcomplicationsmexiletine/therapeuticusenervegrowthfactors/KWDtherapeuticusepain/complications/KWDtherapyperipheralnervoussystemdiseases/complications/KWDtherapynewsletterarticle
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