Squamous cell carcinoma of the anus in patients with AIDS. NLM AIDSLINE Important note: Information in this article was accurate in 1995. The state of the art may have changed since the publication date.

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Squamous cell carcinoma of the anus in patients with AIDS.

Clin Oncol (R Coll Radiol). 1995;7(1):50-1. Unique Identifier : AIDSLINE MED/95244359
Harrison M; Tomlinson D; Stewart S; Clare Hall Laboratories, Imperial Cancer Research Fund, South; Mimms, Hertfordshire, UK.


Abstract: Squamous cell carcinoma of the anus accounts for 2%-3% of all malignancies of the lower gastrointestinal tract. There is an increased incidence in homosexual males who practise receptive and anal intercourse [1]. We report on three cases of squamous cell carcinoma of the anus in patients with the acquired immune deficiency syndrome (AIDS), all of whom were treated with conventional radiotherapy. Increased normal tissue damage with delayed healing was a severe problem in each patient. This led to prolonged delays in delivering an adequate dose of radiotherapy to the site of disease. Reasons for this are explored and suggestions made for the treatment of such patients in the future.
Keywords: Acquired Immunodeficiency Syndrome/*COMPLICATIONS Adult Anus Neoplasms/*COMPLICATIONS/EPIDEMIOLOGY/RADIOTHERAPY AIDS-Related Opportunistic Infections/COMPLICATIONS Carcinoma, Squamous Cell/*COMPLICATIONS/EPIDEMIOLOGY/RADIOTHERAPY Case Report Human Incidence Male Middle Age Support, Non-U.S. Gov't JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/KWDcomplicationsadultanusneoplasms/KWDcomplications/epidemiology/radiotherapyaids-relatedopportunisticinfections/complicationscarcinoma,squamouscell/KWDcomplications/epidemiology/radiotherapycasereporthumanincidencemalemiddleagesupport,non-uKWDsKWDgov'tjournalarticle
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M9580986

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