1995

[Drogen-Report : AIDS-Informationen.]: Nurnberg : Fachverband Freier Einrichtungen in der Suchtarbeit, v. : ill., ports Unique Identifier : AIDSLINE CAT/9506153
Treatment issues : the GMHC newsletter of experimental AIDS therapies. Vol. 1, no. 1 (Nov. 27, 1987)-v. 7, no. 10 (Nov. 1993).: N.Y. [New York] NY : GMHC, [1987-1993] 7 v Unique Identifier : AIDSLINE CAT/9425867
Diagnosis & management of STDs (including AIDS).: Health Division [Adelaide, S. Aust.?] : Public and Environmental Health Division, South Australian Health Commission, [1988] 55 p. : ill (Bulletin ; no. 1) Unique Identifier : AIDSLINE CAT/9400112
[SIDA y sexo.] 1. ed.: [Caracas] : CONICIT, 1988 150 p. : ill (Manuales y monografias) Unique Identifier : AIDSLINE CAT/9402753; Cotte C
[SIDA : la pandemia del siglo.] 1. ed. en M.A.: Caracas : Monte Avila, 1990 225 p. : ill (Estudios) Unique Identifier : AIDSLINE CAT/9403196; Sandner O
The:ethical conduct of AIDS vaccine trials : report of the working party on ethical aspects of AIDS vaccine trials.: Ethical Aspects of AIDS Vaccine Trials London : Medical Research Council, [1991] (1993 printing) 40 p (MRC ethics series) Unique Identifier : AIDSLINE CAT/9506405
[El:SIDA : una realidad en Panama : orientacion practica.] 2. ed.: [Panama? : s.n., 1991?] 62 p. : ill Unique Identifier : AIDSLINE CAT/9406669; Moreno C. JL; Moreno C. JL
A:disease of society : cultural and institutional responses to AIDS.: Cambridge [England] ; New York : Cambridge University Press, 1991 vii, 287 p Unique Identifier : AIDSLINE CAT/9506022; Nelkin D; Willis DP; Parris S
[SIDA, le suivi de l'epidemie au Quebec : reflexions sur un bilan des Drs. Robert Remis et Elise Roy.]: [Quebec] : Direction generale de la planification et de l'evaluation, Ministere de la sante et des services sociaux, [1991] 35 p Unique Identifier : AIDSLINE CAT/9503438; Remis RS
[AIDS na rota da cocaina : um conto santista.]: Sao Paulo, Brasil : Editora Anita Garibaldi, 1992 69 p. : ill., ports Unique Identifier : AIDSLINE CAT/9439429; Mesquita F
[AIDS und homo- und bisexuelle Verhalten ind [i.e. in] Deutschland : Vortrag am 26.03.1992 auf dem 4. Deutschen AIDS-Krongress [sic] in Wiesbaden.]: Luneburg : Universitat Luneburg, Fachbereich Wirtschafts- und Sozialwissenschaften, [1992] 11, 8 p. : ill (Arbeitsbericht, ISSN 0176-7275 ; Nr. 114) Unique Identifier : AIDSLINE CAT/9440920; Runkel G
[Catalogue de reactifs.]: Paris : ANRS, [1992] 1 v. (various pagings) Unique Identifier : AIDSLINE CAT/9423786
[Le:sida, 1981-1985 : les debuts d'une pandemie.]: Paris : La documentation francaise, 1993 128 p. : ill., ports (Les medias et l'evenement, ISSN 0297-4088) Unique Identifier : AIDSLINE CAT/9504618; Strazzulla J
Human immunodediciency virus and hepatitis B and the workplace.: Canberra : Australian Govt. Pub. Service, c1993 viii, 66 p. : ill Unique Identifier : AIDSLINE CAT/9505238
The:health and social care of people with HIV infection and AIDS : findings and good practice recommendations from research funded by the Department of Health, 1986-1992.: London : HMSO, 1993 iii, 78 p Unique Identifier : AIDSLINE CAT/9505487
[Compte rendu du Colloque Prevention et V.I.H--Necessaire illusion?.]: Lyon : Edition Fondation Marcel Merieux, [1993?] 191 p. : ports Unique Identifier : AIDSLINE CAT/9504636
School guidelines for HIV/AIDS prevention and health education.: Roma : Ministero della sanita, Istituto superiore di sanita, 1994 73 p (Rapporti ISTISAN, ISSN 0391-1675 ; ISTISAN 94/11) Unique Identifier : AIDSLINE CAT/9505763; Bertinato L
[Staatshaftung fur HIV-kontaminierte Blutprodukte : eine Fallstudie.] 1. Aufl.: Baden-Baden : Nomos Verlagsgesellschaft, 1994 xi, 73 p (Forum Rechtswissenschaft ; Bd. 26) Unique Identifier : AIDSLINE CAT/9502058; Bruggemeier G
AIDS and human reproduction = SIDA et reproduction.: Montpellier, France : Sauramps Medical, c1994 360 p. : ill Unique Identifier : AIDSLINE CAT/9508514
Focusing interventions among vulnerable groups for HIV infection : experiences from eastern and southern Africa.: Nairobi : Network of AIDS Researchers of Eastern and Southern Africa, 1994 vi, 124 p (NARESA monograph ; no. 2) Unique Identifier : AIDSLINE CAT/9505144
Report of a consultation on women and HIV/AIDS, Geneva, 6-8 December 1993.: [Geneva] : World Health Organization, c1994 33 p Unique Identifier : AIDSLINE CAT/9508748
Report on the Consultative Meeting on Leishmania/HIV Co-infection : Rome, 6-7 September 1994.: [Geneva?] : World Health Organization, [1995?] 14 p Unique Identifier : AIDSLINE CAT/9508373
[AIDS und Prostitution.]: Frankfurt/Main : VAS, c1994 95 p. : ill Unique Identifier : AIDSLINE CAT/9440002; Bolender C
AIDS in prison.: Aldershot ; Brookfield, USA : Dartmouth, c1994 148 p Unique Identifier : AIDSLINE CAT/9506623; Thomas PA; Moerings M
AIDS : telling it like it is.: Anchorage, AK : State of Alaska, Dept. of Health & Social Services, Division of Public Health, Section of Epidemiology, [1994] iv, 64 p. : ill Unique Identifier : AIDSLINE CAT/9507324; Cordes PM
GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies. Vol. 7, no. 11/12 (winter 1993/94)-: New York, NY : GMHC, c1993- v Unique Identifier : AIDSLINE CAT/9509489
Adapting WHO guidelines for the clinical management of HIV infection to country needs.: [Geneva?] : World Health Organization, c1995 29 p. : ill Unique Identifier : AIDSLINE CAT/9507934
Altered conditions : disease, medicine, and storytelling.: New York : Routledge, c1995 x, 275 p. : ill Unique Identifier : AIDSLINE CAT/9505716; Epstein J
AIDS : readings on a global crisis.: Boston : Allyn and Bacon, c1995 xvi, 380 p. : ill., ports Unique Identifier : AIDSLINE CAT/9506077; Bethel ER
Guide to books on AIDS.: New York : Nova Science Publishers, c1995 98 p Unique Identifier : AIDSLINE CAT/9506904; Russel RP
Oral manifestations of HIV infection : proceedings of the Second International Workshop on the Oral Manifestations of HIV Infection, January 31-February 3, 1993, San Francisco, California.: Chicago : Quintessence Pub. Co., c1995 381 p. : ill Unique Identifier : AIDSLINE CAT/9507691; Greenspan JS; Greenspan D; Infection
Stedman's radiology & oncology words : including HIV-AIDS, hematology. 2nd ed.: Baltimore : Williams & Wilkins, c1995 xvi, 620, 53 p (Stedman's word book series) Unique Identifier : AIDSLINE CAT/9509291; Baxter CS; Stedman TL
AIDS literature & law review. Vol. 1, no. 1-2 (Jan.-Feb. 1995)-: Frederick, Md. : University Pub. Group, c1995- v Unique Identifier : AIDSLINE CAT/9508188
AIDS sourcebook : basic information about AIDS and HIV infection featuring historical and statistical data, current research, prevention, and other special topics of interest for persons living with AIDS along with source listings for further assistance.: Detroit, MI : Omnigraphics, 1995 x, 831 p. : ill (Health reference series ; v. 4) Unique Identifier : AIDSLINE CAT/9507944; Bellenir K; Dresser PD
HIV-negative : how the uninfected are affected by AIDS.: New York : Insight Books, c1995 xii, 332 p Unique Identifier : AIDSLINE CAT/9508727; Johnston WI
Palliative care for people with AIDS. 2nd ed.: London : E. Arnold, 1995 xix, 170 p. : ill Unique Identifier : AIDSLINE CAT/9503813; Sims R; Moss VA
Seeking fair treatment : from the AIDS epidemic to national health care reform.: New York : Oxford University Press, 1995 ix, 204 p Unique Identifier : AIDSLINE CAT/9508463; Daniels N
AIDS research at EC level.: Amsterdam ; Washington, DC : IOS Press, 1995 xiii, 371 p. : ill (Biomedical and health research, ISSN 0929-6743 ; v. 6) Unique Identifier : AIDSLINE CAT/9507869; Baert AE
Changing HIV risk behavior : practical strategies.: New York : Guilford Press, 1995 (Treatment manuals for practitioners) Unique Identifier : AIDSLINE CAT/9509726; Kelly JA
Chronic diseases.: Mahwah, N.J. : L. Erlbaum Associates, 1995 (Perspectives in behavioral medicine) Unique Identifier : AIDSLINE CAT/9509720; Stein M; Baum A
Feline immunology and immunodeficiency.: Oxford ; New York : Oxford University Press, 1995 xi, 359 p. : ill (Oxford science publications) Unique Identifier : AIDSLINE CAT/9508711; Willett BJ; Jarrett O
[HIV-Infektion im Kindesalter.]: Stuttgart ; New York : Gustav Fischer Verlag, 1995 xvi, 405 p. : ill Unique Identifier : AIDSLINE CAT/9507221; Rudin C
Journal of the International Association of Physicians in AIDS Care. Began with: Vol. 1, no. 1 (Feb. 1995).: Chicago, Ill. : Medical Publications Corp., c1995- v. : ill Unique Identifier : AIDSLINE CAT/9508185
Teenagers and AIDS in America.: New York : Nova Science Publishers, c1994 ix, 219 p. : ill Unique Identifier : AIDSLINE CAT/9508706; Stango J
Human medicinal agents from plants.: ACS Symp Ser; 534:1-356 1993. Unique Identifier : AIDSLINE ICDB/95615459; Kinghorn AD; Balandrin MF; Coll. of Pharmacy, Univ. of Illinois at Chicago, Chicago, IL; 60612; The records of early medicine are replete with remedies based on plant materials, and to this day, agents derived from plants or based structurally on prototypes of plant origin figure prominently. This book was developed from a symposium sponsored by the Division of Agricultural and Food Chemistry at the 203rd Nation
Design, synthesis and evaluation of potential glycoside hydrolase inhibitors based on castanospermine and swainsonine.: Diss Abstr Int [B]; 55(3):1051 1994. Unique Identifier : AIDSLINE ICDB/95607537; Tan P; State Univ. of New York at Buffalo; A family of new analogues of polyhydroxylated indolizidine alkaloids swainsonine and castanospermine was synthesized and evaluated as potential inhibitors of alpha-mannosidase or alpha-glucosidase, the enzymes required in the secondary processing of glycoprotein biosynthesis in HIV virus and tumor cells. N-swainsonine
Role of tumor suppressor phosphoprotein p53 in signal transduction during lymphocyte activation: implications for viral pathogenesis.: Diss Abstr Int [B]; 55(3):811 1994. Unique Identifier : AIDSLINE ICDB/95607551; McClure JE; Baylor College of Medicine; Employing the competition RIA for studies of the levels of Domain V in sub-cellular compartments during acute stimulations of CHX-treated lymphocytes, we observed rapidly (10-20 min) increased levels of cytosolic IRp53 and decreased levels of nuclear IRp53. We determined that a 3- to 4-fold increase of readily-extract
Murine leukemia virus infection in immunocompetent adult mice.: Diss Abstr Int [B]; 55(5):1795 1994. Unique Identifier : AIDSLINE ICDB/95607692; Tumas KM; Univ. of Pennsylvania; Murine leukemia viruses (MuLVs) are retroviruses which induce several types of hemopoietic diseases in susceptible mice. To investigate leukemia development in immunocompetent adult mice, we have utilized the MuLV, E-55(+), which induces a T cell lymphoma/leukemia in adult BALB.K mice after a latency period of approxi
Identification of a gene(s) involved in carcinogenic progression of ataxia telangiectasia cells (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 36:A857 1995. Unique Identifier : AIDSLINE ICDB/95608636; Jung M; Zhang Y; Dritschilo A; Georgetown University Medical Center, Washington, DC 20007; Genetic mechanisms have been correlated to phenotypic changes observed in the steps involved in immortalization, promotion, and progression to tumorigenicity. Using ataxia telangiectasia (AT) fibroblasts as a model system, we have employed vector-mediated gene transfer and expression cloning to identify candidate cDNA
Didanosine (ddI) ameliorates neutropenia in patients with HIV-related non-Hodgkin's lymphoma (NHL) treated with infusional cyclophosphamide, doxorubicin, and etoposide (CDE) (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 36:A1207 1995. Unique Identifier : AIDSLINE ICDB/95608984; Sparano JA; Wiernik PH; Leaf A; Henry D; Mason B; Sarta C; Hu X; Dutcher JP; Montefiore Medical Center, Bronx, NY 10467; We reported a 62% complete response (CR) rate and 18-mo median survival for 21 patients (pts) with HIV-related NHL treated with infusional CDE (Blood 81:2810, 1993; Leukemia and Lymphoma 14:263, 1994), but observed substantial myelosuppression and decreased CD4+ lymphocytes (111/ul +/- 23 pre vs 52 +/- 12 post 2 cycle
AIDS-Kaposi's sarcoma growth and glucocorticoids (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 36:A1209 1995. Unique Identifier : AIDSLINE ICDB/95608986; Guo WX; Gill P; Antakly T; Departement de pathologie, Universite de Montreal Canada H3C 3J7; Glucocorticoid therapy as an immunosuppressive agent has been linked to increased risk of development of Kaposi s sarcoma (KS) which has become epidemic in HIV infected individuals. However, no experimental evidence is available to explain how glucocorticoid may be responsible for KS growth. We investigated the direct
HIV-tat product is angiogenic in vivo and mimics heparin-binding angiogenic growth factors (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 36:A540 1995. Unique Identifier : AIDSLINE ICDB/95608319; Albini A; Masiello L; Benelli R; Presta M; Rusnati M; Bussolino F; Soldi R; Noonan D; Istituto Nazionale per la Ricerca sul Cancro, 16132 Genova, Italy; Transgenic animal studies have linked expression of the HIV-tat gene to the appearance of Kaposi s sarcoma (KS)-like lesions (an angiogenic tumor associated with AIDS), and tat has been shown to be a growth factor for KS and activated endothelial cells. tat is also chemotactic for vascular cells. We have shown that re
Results of a phase I trial of the novel angiogenesis inhibitor, tecogalan sodium (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 36:A628 1995. Unique Identifier : AIDSLINE ICDB/95608407; Eckhardt SG; Eckardt JR; Weiss G; Rinaldi D; Rodriguez G; Fields S; Kuhn J; Smetzer L; Higashi L; Von Hoff DD; et al; Cancer Therapy and Res. Center, San Antonio, TX 78229; Tecogalan sodium is a novel angiogenesis inhibitor isolated from a low mol wt fraction of a sulfated polysaccharide produced by the bacterium Arthrobacter. The antitumor effect of tecogalan sodium is thought to be mediated by the inhibition of the binding of fibroblast growth factor to cellular receptors. We have cond
AIDS surveillance in Canada.: Can Commun Dis Rep. 1992 Mar 13;18(5):33-6. Unique Identifier : AIDSLINE MED/95253091
[Tuberculosis and AIDS in Paraguay]: Bol Oficina Sanit Panam. 1995 Mar;118(3):248-53. Unique Identifier : AIDSLINE MED/95244013; Galeano Jimenez AH; Programa Nacional de Lucha contra el SIDA, Departamento de; Atencion Medica, LACIMET, Asuncion, Paraguay.
Rapid screening of open reading frames by protein synthesis with an in vitro transcription and translation assay.: Biotechniques. 1995 Feb;18(2):244-8. Unique Identifier : AIDSLINE MED/95244141; Switzer WM; Heneine W; Retrovirus Diseases Branch, Centers for Disease Control and; Prevention, Atlanta, GA 30333, USA.; The analysis of open reading frames (ORFs) to predict full-length or truncated proteins in genes is conventionally achieved by DNA sequencing. This method becomes labor-intensive when a large number of specimens or when large genes are to be examined. To circumvent this problem, we used an in vitro transcription and t
[Candida esophagitis and cytomegalovirus gastritis: optic and immunohistochemical diagnosis in an HIV+ patient]: Rev Esp Enferm Dig. 1995 Jan;87(1):49-52. Unique Identifier : AIDSLINE MED/95244183; Vera-Sempere FJ; Ramos V; Blanes M; Sala T; Prieto M; Cortes B; Hospital Universitario La Fe, Valencia.; Esophageal candidiasis, along with gastritis caused by cytomegalovirus--CMV--, is a common opportunistic infection in immunodepressed patients. A clinico-pathological description is made of a human immunodeficiency virus-positive female (group IV-C-2) with a history of odynophagia and dysphagia resistant to treatment.
[Apoptosis or programmed cell death: regulatory and pathophysiological mechanisms (editorial)]: Ann Ital Med Int. 1995 Jan-Mar;10(1):7-13. Unique Identifier : AIDSLINE MED/95244238; Silvestris F; Ribatti D; Nico B; Silvestris N; Romito A; Dammacco F; Apoptosis is an active death process genetically encoded to eliminate abnormal or unwanted cells. The phenomenon is induced by a cascade of molecular events leading to nucleolysis by endonucleases and involves a number of membrane receptors and cytoplasmic proteins. These structures (including Fas, mullerian inhibitin
Concern over additions to HIV test programme [news]: Nurs Stand. 1995 Mar 15-21;9(25):8. Unique Identifier : AIDSLINE MED/95244278
Health education: send them packing.: Nurs Stand. 1995 Mar 22-28;9(26):55. Unique Identifier : AIDSLINE MED/95244289; Wright J
AIDS dementia complex: guidelines for nursing care.: Axone. 1994 Dec;16(2):37-46. Unique Identifier : AIDSLINE MED/95244346; Wyness MA; AIDS dementia complex is one of the most common neurological problems associated with HIV-related illness. To date, the nursing care of individual with AIDS dementia complex has not been explored to any extent. As a basis for examining aspects of nursing care, the epidemiology, neu
Squamous cell carcinoma of the anus in patients with AIDS.: Clin Oncol (R Coll Radiol). 1995;7(1):50-1. Unique Identifier : AIDSLINE MED/95244359; Harrison M; Tomlinson D; Stewart S; Clare Hall Laboratories, Imperial Cancer Research Fund, South; Mimms, Hertfordshire, UK.; Squamous cell carcinoma of the anus accounts for 2%-3% of all malignancies of the lower gastrointestinal tract. There is an increased incidence in homosexual males who practise receptive and anal intercourse [1]. We report on three cases of squamous cell carcinoma of the anus in patients with the acquired immune defic
CD4+ T lymphocyte infiltration correlates with regression of a UV-induced squamous cell carcinoma.: J Dermatol Sci. 1995 Jan;9(1):12-9. Unique Identifier : AIDSLINE MED/95244405; Patel A; Halliday GM; Barnetson RS; Department of Dermatology, University of Sydney, Royal Prince; Alfred Hospital, Australia.; It is currently unknown which arm of the immune system is responsible for regression of tumours. We have studied the T lymphocytes infiltrating a spontaneously regressing murine squamous cell carcinoma during the growth, plateau and regression phases of tumour development. In the plateau phase, where tumour growth is
Cellular and molecular mechanisms of human cardiac myocyte injury after transplantation.: J Heart Lung Transplant. 1995 Jan-Feb;14(1 Pt 1):102-12. Unique Identifier : AIDSLINE MED/95244530; Ansari AA; Sundstrom JB; Kanter K; Mayne A; Villinger F; Gravanis MB; Herskowitz A; Dept. of Pathology and Laboratory Medicine, Winship Cancer; Center, Emory University, Atlanta, GA 30322, USA.; BACKGROUND: Fetal human cardiac myocytes or a cell line derived from fetal human cardiac myocytes, termed W1, even after experimental induction of normal levels of major histocompatibility complex class I and II antigens, fail to induce the activation of primary allogeneic responses. Therefore, our laboratory has inve
The sexual transmission of hepatitis C virus [editorial]: Int J STD AIDS. 1995 Jan-Feb;6(1):1-3. Unique Identifier : AIDSLINE MED/95244657; Scott GR
Why do condoms break or slip off in use? An exploratory study.: Int J STD AIDS. 1995 Jan-Feb;6(1):11-8. Unique Identifier : AIDSLINE MED/95244658; Richters J; Gerofi J; Donovan B; Department of Public Health, University of Sydney, Australia.; Men attending 3 sexually transmissible disease clinics and a university health clinic in Sydney, Australia , were invited to complete a questionnaire on their use of condoms. Respondents were 108 male condom user volunteers aged 18 to 62 years; in the last five years 47 had had s
A comparison of zidovudine, didanosine, zalcitabine and no antiretroviral therapy in patients with advanced HIV disease.: Int J STD AIDS. 1995 Jan-Feb;6(1):19-26. Unique Identifier : AIDSLINE MED/95244659; Torres RA; Barr MR; McIntyre KI; Thornton JR; Shay WM; Feldman RD; George NJ; Britton DJ; AIDS Center, St Vincent's Hospital and Medical Center of New; York, NY 10011, USA.; Three nucleoside analogues, zidovudine ( AZT ), didanosine (ddI), and zalcitabine ( ddC ), are approved for use in the treatment of patients with HIV infection. This retrospective study c
Chlamydial urethritis in heterosexual men attending a genitourinary medicine clinic: prevalence, symptoms, condom usage and partner change [see comments]: Int J STD AIDS. 1995 Jan-Feb;6(1):27-30. Unique Identifier : AIDSLINE MED/95244660; Zelin JM; Robinson AJ; Ridgway GL; Allason-Jones E; Williams P; Department of Genitourinary Medicine, University College London; Hospitals, UK.; A prospective study of 356 consecutive heterosexual male patients attending the Department of Genitourinary Medicine at University College Hospital was carried out to determine the prevalence of Chlamydia trachomatis. Patients were asked about their symptoms, use of condoms and change of sexual partner. The prevalence
Sexual behaviour in the city of Lisbon.: Int J STD AIDS. 1995 Jan-Feb;6(1):35-41. Unique Identifier : AIDSLINE MED/95244662; Amaro F; Dantas AM; Teles L da C; Technical University of Lisbon, Portugal.; This study of sexual behaviour in the city of Lisbon is based on data obtained from 2 random samples, one of individuals aged 16-20 (n = 400) and another of individuals over the age of 20 (n = 400). Samples have been stratified by district, gender and age. Data were obtained by personal interview and by questionnaires
Ulcerative disease of the anorectum in AIDS [editorial]: Int J STD AIDS. 1995 Jan-Feb;6(1):4-6. Unique Identifier : AIDSLINE MED/95244663; Gottesman L
Syphilis and HIV infection among prisoners in Maputo, Mozambique.: Int J STD AIDS. 1995 Jan-Feb;6(1):42-6. Unique Identifier : AIDSLINE MED/95244664; Vaz RG; Gloyd S; Folgosa E; Kreiss J; National Institute of Health, Ministry of Health, Maputo,; Mozambique.; A cross-sectional study was carried out among 1284 male and 54 female prisoners to assess the prevalence of and risk factors for sexually transmitted diseases (STD) in 4 correctional institutions of Maputo, Mozambique . Among the men, 32% reported a history of prostitute contact
Experience of HIV disease in a London District General Hospital.: Int J STD AIDS. 1995 Jan-Feb;6(1):47-9. Unique Identifier : AIDSLINE MED/95244665; Coker RJ; Desmond N; Poznansky M; Smith C; Shafi MS; Bell D; Riordan JF; Murphy S; Department of Genitourinary Medicine, Central Middlesex Hospital; NHS Trust, London, UK.; The aim of this paper is to describe and discuss the experience of HIV disease in Central Middlesex Hospital, London up to June 1993. A retrospective study of the total number of HIV-positive patients cared for was performed. In addition, prospectively collected data as part of local epidemiological surveillance from
HIV seroconversion illness after orogenital contact with successful contact tracing.: Int J STD AIDS. 1995 Jan-Feb;6(1):50-1. Unique Identifier : AIDSLINE MED/95244666; Edwards SK; White C; Department of Genito-Urinary Medicine, Dryburn Hospital, Durham,; UK.
Unusual manifestations of early syphilis in a married male. Florid manifestations of condylomata lata on the face.: Int J STD AIDS. 1995 Jan-Feb;6(1):52-3. Unique Identifier : AIDSLINE MED/95244667; Sundararaj AS; Williams J; Gopinathan R; Deivam S; Department of STD, Government RajaMirasudhar Hospital, Thanjavur,; Tamilnadu, India.
Urethral rupture in a homosexual male following avulsion of a 'Prince Albert' penile ring.: Int J STD AIDS. 1995 Jan-Feb;6(1):54-5. Unique Identifier : AIDSLINE MED/95244668; Higgins SP; Estcourt CS; Bhattacharyya MN; Department of Genitourinary Medicine, Manchester Royal Infirmary,; UK.
Disseminated candidiasis in two HIV-positive intravenous drug users.: Int J STD AIDS. 1995 Jan-Feb;6(1):56-8. Unique Identifier : AIDSLINE MED/95244669; de Ruiter A; Lloyd M; Wood C; Graham E; Bingham JS; Department of Genitourinary Medicine, St Thomas' Hospital,; London, UK.
Screening for hepatitis B, hepatitis C and syphilis at two genitourinary medicine clinics.: Int J STD AIDS. 1995 Jan-Feb;6(1):59-60. Unique Identifier : AIDSLINE MED/95244670; Newell A; Watson-Jones D; Evans BA; Barton SE; Department of Genitourinary Medicine, Charing Cross Hospital,; London, UK.
Accuracy of computerized diagnostic records for Chlamydia, syphilis, gonorrhoea and herpes.: Int J STD AIDS. 1995 Jan-Feb;6(1):60. Unique Identifier : AIDSLINE MED/95244671; Brook MG; Kell PD; Atia WA; Archway Sexual Health Clinic, Camden & Islington Community Health; Services NHS Trust, Whittington Hospital, Highgate Hill, London,; UK.
An audit of pharyngeal infection in patients attending GUM clinic in Sunderland.: Int J STD AIDS. 1995 Jan-Feb;6(1):60-1. Unique Identifier : AIDSLINE MED/95244672; Tayal SC; Rashid S; Muttu KM; Department of Genito-Urinary Medicine, Sunderland Distric General; Hospital, UK.
International Union Against the Venereal Diseases and the Treponematoses: an overview [news]: Int J STD AIDS. 1995 Jan-Feb;6(1):62-1. Unique Identifier : AIDSLINE MED/95244673; Waugh M
Report of the Regional Director for North America, International Union Against the Venereal Diseases and Treponematoses [news]: Int J STD AIDS. 1995 Jan-Feb;6(1):63-5. Unique Identifier : AIDSLINE MED/95244674; Drusin LM
Referral of cases of gonococcal infection [letter; comment]: Int J STD AIDS. 1995 Jan-Feb;6(1):68. Unique Identifier : AIDSLINE MED/95244675; Ross JD; Young H
Falling prevalence of Chlamydia trachomatis infection--no time for complacency [letter] [see comments]: Int J STD AIDS. 1995 Jan-Feb;6(1):68-9. Unique Identifier : AIDSLINE MED/95244676; Robinson AJ; Ridgway GL; Zelin J; Williams P
Developments in the radiological investigation of the lower urinary tract [editorial]: Int J STD AIDS. 1995 Jan-Feb;6(1):7-10. Unique Identifier : AIDSLINE MED/95244677; Noble J; Rickards D
Alcohol abuse and HIV infection have additive effects on frontal cortex function as measured by auditory evoked potential P3A latency [see comments]: Biol Psychiatry. 1995 Feb 1;37(3):183-95. Unique Identifier : AIDSLINE MED/95244709; Fein G; Biggins CA; MacKay S; Department of Psychiatry, University of California, San; Francisco, USA.; Both alcohol and human immunodeficiency virus (HIV) infection have been shown to produce central nervous system (CNS) morbidity in frontal brain regions. The degree to which the CNS morbidity in HIV infection, as it affects frontal cortex function, may be preferentially increased by alcohol abuse was examined using th
Photo quiz. Bacillary angiomatosis.: Clin Infect Dis. 1995 Jan;20(1):15, 159. Unique Identifier : AIDSLINE MED/95244723; Adal KA; Berne J; Stoler MH; Division of Infectious Diseases, University of Virginia Health; Sciences Center, Charlottesville.
Rhodococcus meningitis in an immunocompetent host.: Clin Infect Dis. 1995 Jan;20(1):167-9. Unique Identifier : AIDSLINE MED/95244727; DeMarais PL; Kocka FE; Department of Medicine, Cook County Hospital, Chicago, Illinois; 60612.; Rhodococcus species are increasingly being recognized as pathogens, especially in patients infected with the human immunodeficiency virus. Most cases of rhodococcus infection in these patients are due to Rhodococcus equi and involve the lungs. CNS infections due to Rhodococcus species are rare, and meningitis due to n
Infection due to parvovirus B19 in patients infected with human immunodeficiency virus.: Clin Infect Dis. 1995 Jan;20(1):170-3. Unique Identifier : AIDSLINE MED/95244728; Chernak E; Dubin G; Henry D; Naides SJ; Hodinka RL; MacGregor RR; Friedman HM; Department of Medicine, Hospital of the University of; Pennsylvania.; Parvovirus B19 has been described as a cause of chronic anemia in immunosuppressed patients, including those infected with human immunodeficiency virus (HIV). In this study serological assays and the polymerase chain reaction (PCR) were used to establish the prevalence of both prior and active infection due to parvovi
Efficacy of liposomal amphotericin B in the treatment of visceral leishmaniasis in patients coinfected with the human immunodeficiency virus [letter; comment]: Clin Infect Dis. 1995 Jan;20(1):191. Unique Identifier : AIDSLINE MED/95244734; Torre-Cisneros J; Villanueva JL
Bordetella bronchiseptica infection in patients with AIDS [letter; comment]: Clin Infect Dis. 1995 Jan;20(1):193-4. Unique Identifier : AIDSLINE MED/95244736; Woodard DR; Cone LA; Fostvedt K
Acute suppurative Salmonella enteritidis thyroiditis associated with thyrotoxicosis in a patient infected with the human immunodeficiency virus [letter]: Clin Infect Dis. 1995 Jan;20(1):196. Unique Identifier : AIDSLINE MED/95244738; Lecuit M; Caumes E; Bricaire F; Gatineau M; Menegaux F; Gentilini M
Use of diclazuril for the treatment of isosporiasis in patients with AIDS [letter]: Clin Infect Dis. 1995 Jan;20(1):201-2. Unique Identifier : AIDSLINE MED/95244742; Limson-Pobre RN; Merrick S; Gruen D; Soave R
Community-acquired pneumonia due to Acinetobacter lwoffii in a patient infected with the human immunodeficiency virus [letter]: Clin Infect Dis. 1995 Jan;20(1):205-6. Unique Identifier : AIDSLINE MED/95244745; Domingo P; Munoz R; Frontera G; Pericas R; Martinez E
Myelitis due to varicella-zoster virus in an immunocompromised patient without a cutaneous rash [letter]: Clin Infect Dis. 1995 Jan;20(1):206-8. Unique Identifier : AIDSLINE MED/95244746; Meylan PR; Miklossy J; Iten A; Petignat C; Meuli R; Zufferey J; Sahli R
Isolation of nontuberculous, non-avium mycobacteria from patients infected with human immunodeficiency virus.: Clin Infect Dis. 1995 Jan;20(1):73-6. Unique Identifier : AIDSLINE MED/95244756; Raszka WV Jr; Skillman LP; McEvoy PL; Robb ML; Department of Pediatrics, William Beaumont Army Medical Center,; El Paso, Texas 79920.; Mycobacterium avium serovars account for 97% of typeable M. avium complex (MAC) organisms causing infection in patients with AIDS. We reviewed 216 consecutive cultures that yielded nontuberculous mycobacteria (NTM) from 212 patients. Only the first isolate of each species of NTM recovered from each patient was analyze
Isolation of fluconazole-resistant Candida albicans from human immunodeficiency virus-negative patients never treated with azoles.: Clin Infect Dis. 1995 Jan;20(1):77-83. Unique Identifier : AIDSLINE MED/95244757; Goff DA; Koletar SL; Buesching WJ; Barnishan J; Fass RJ; Department of Pharmacy, Ohio State University Medical Center,; Columbus.; Isolation of fluconazole-resistant strains of Candida species from human immunodeficiency virus (HIV)-infected patients after repeated or continuous courses of treatment has been reported with increasing frequency. During 1991-1992, MICs of fluconazole for 139 Candida albicans isolates from our institution were bimoda
The ENCEL system: a somatic cell protein delivery system.: In Vivo. 1994 Nov-Dec;8(5):771-80. Unique Identifier : AIDSLINE MED/95244808; Squinto SP; Madri JA; Kennedy S; Springhorn J; Alexion Pharmaceuticals, Inc, New Haven, CT 06511, USA.; A wide variety of somatic cells are being explored for the introduction of foreign genes with a view toward gene therapy. A prime requirement for successful gene therapy is the sustained expression, effective dosing, and systemic delivery of the therapeutic gene product. Microvascular endothelial cells offer several a
CD8+ T lymphocytes in the lung of acquired immunodeficiency syndrome patients harbor human immunodeficiency virus type 1.: Blood. 1995 May 1;85(9):2308-14. Unique Identifier : AIDSLINE MED/95244849; Semenzato G; Agostini C; Ometto L; Zambello R; Trentin L; Chieco-Bianchi L; De Rossi A; Padua University School of Medicine, Institutes of Clinical; Medicine and Oncology, Italy.; Human immunodeficiency virus-1 (HIV-1) infection of CD8+ lymphocytes has been described in several in vitro culture systems, but whether CD8+ cells are a target and also serve as a reservoir for infection in vivo as yet is unknown. We addressed this issue in patients with acquired immunodeficiency syndrome (AIDS)-rela
Randomized study of didanosine monotherapy and combination therapy with zidovudine in hemophilic and nonhemophilic subjects with asymptomatic human immunodeficiency virus-1 infection. AIDS Clinical Trial Groups.: Blood. 1995 May 1;85(9):2337-46. Unique Identifier : AIDSLINE MED/95244853; Ragni MV; Amato DA; LoFaro ML; DeGruttola V; Van Der Horst C; Eyster ME; Kessler CM; Gjerset GF; Ho M; Parenti DM; et al; Department of Medicine, University of Pittsburgh School of; Medicine, PA, USA.; To evaluate the safety and efficacy of didanosine (ddl) monotherapy and three different combinations of zidovudine (ZDV) and ddl in asymptomatic human immunodeficiency virus-1 (HIV-1) infection, we conducted an open-label, phase I/II study in 126 asymptomatic HIV-1-infected hemophilic and nonhemophilic subjects with a
Expression of the blood-clotting factor-VIII cDNA is repressed by a transcriptional silencer located in its coding region.: Blood. 1995 May 1;85(9):2447-54. Unique Identifier : AIDSLINE MED/95244865; Hoeben RC; Fallaux FJ; Cramer SJ; van den Wollenberg DJ; van Ormondt H; Briet E; van der Eb AJ; Department of Medical Biochemistry, University of Leiden, The; Netherlands.; Hemophilia A is caused by a deficiency of factor-VIII procoagulant (fVIII) activity. The current treatment by frequent infusions of plasma-derived fVIII concentrates is very effective but has the risk of transmittance of blood-borne viruses (human immunodeficiency virus [HIV], hepatitis viruses). Use of recombinant DN
Smoldering adult T-cell leukemia with B-cell lymphoma and early gastric cancer.: Intern Med. 1995 Feb;34(2):118-21. Unique Identifier : AIDSLINE MED/95245003; Kodama M; Matsuoka H; Maeda K; Suzuki M; Okayama A; Uno H; Tachibana N; Komada N; Kouno M; Ohshima K; et al; Second Department of Internal Medicine, Miyazaki Medical School.; We report a case of smoldering adult T-cell leukemia (ATL) with B-cell lymphoma and early gastric cancer. A 64-year-old man was admitted to our hospital because of proteinuria and hypergammaglobulinemia. Systemic lymphadenopathy, flower cells in peripheral white blood cells, and hypergammaglobulinemia with monoclonal
[Survey of blood donors on the topic of reimbursement for blood donors]: Infusionsther Transfusionsmed. 1995 Feb;22(1):19-24. Unique Identifier : AIDSLINE MED/95245098; Zeiler T; Kretschmer V; Abteilung fur Transfusionsmedizin und Gerinnungsphysiologie der; Philipps-Universitat Marburg.; BACKGROUND: Remuneration for blood donors, in the way as presently handled by governmental and communal blood transfusion services in Germany , is not generally accepted. It is feared that donors are recruited with increased risk to transmit infectious diseases, especially AIDS. Al
[Risk of HIV transmission by blood transfusion (letter)]: Infusionsther Transfusionsmed. 1995 Feb;22(1):46-8. Unique Identifier : AIDSLINE MED/95245103; Kohler M
Researchers in US dispute first case of AIDS [news]: BMJ. 1995 Apr 15;310(6985):957. Unique Identifier : AIDSLINE MED/95245181; Connor S
AIDS strategy must pay more attention to human rights [news]: BMJ. 1995 Apr 15;310(6985):957-8. Unique Identifier : AIDSLINE MED/95245182; Smith R
Report of French blood scandal is leaked to press [news]: BMJ. 1995 Apr 15;310(6985):959. Unique Identifier : AIDSLINE MED/95245184; Dorozynski A
Polymorphism of the thymidylate synthase gene of Pneumocystis carinii from different host species.: J Eukaryot Microbiol. 1995 Jan-Feb;42(1):26-32. Unique Identifier : AIDSLINE MED/95245322; Mazars E; Odberg-Ferragut C; Dei-Cas E; Fourmaux MN; Aliouat EM; Brun-Pascaud M; Mougeot G; Camus D; INSERM (U. 42), Villeneuve d'Ascq, France.; Pneumocystis carinii is an opportunistic agent found in the lung of various mammals which often causes severe pneumonia in immunocompromised humans, especially in AIDS patients. In the past several years significant additions have been made to the collection of knowledge we have concerning the genetic diversity of P.
Tuberculosis in children.: Curr Opin Pediatr. 1995 Feb;7(1):6-12. Unique Identifier : AIDSLINE MED/95245401; Costello AM; Rook G; University of London, UK.; Tuberculosis in children is a growing problem, both globally and in many industrialized countries. With a rising incidence, clinicians will again face the challenge of the myriad presentations of tuberculous disease. Multidrug resistance and HIV coinfection present additional complications. Renewed interest in tubercu
HIV/AIDS exhibition a first for Australia [news]: Aust Nurs J. 1994 Nov;2(5):9. Unique Identifier : AIDSLINE MED/95245436
[Understanding AIDS in Brazil]: Rev Lat Am Enfermagem. 1995 Jan;3(1):149-58. Unique Identifier : AIDSLINE MED/95245440; Nichiata LY; Shima H; Takahashi RF
Bioethics update: HIV testing.: Nurs Spectr (Wash D C). 1995 Feb 6;5(3):14. Unique Identifier : AIDSLINE MED/95245452; Edwards BS
[Pain and AIDS (editorial)]: Cah Anesthesiol. 1994;42(5):565-6. Unique Identifier : AIDSLINE MED/95245860; Saint-Maurice C
CD8+ T cells from a patient with colon carcinoma, specific for a mutant p21-Ras-derived peptide (Gly13-->Asp), are cytotoxic towards a carcinoma cell line harbouring the same mutation.: Cancer Immunol Immunother. 1995 Mar;40(3):165-72. Unique Identifier : AIDSLINE MED/95246048; Fossum B; Olsen AC; Thorsby E; Gaudernack G; Institute of Transplantation Immunology, National Hospital,; University of Oslo, Norway.; Several T lymphocyte clones (TLC), specific for a p21-Ras-derived peptide expressing a Gly13-->Asp mutation and of the CD8+ subtype, were generated from peripheral blood of a colon carcinoma patient. The TLC exerted cytotoxicity against an interferon-gamma (IFN gamma)-pretreated colon carcinoma cell line, HCT116, whic
The antitumor effect of tumor-draining lymph node cells activated by both anti-CD3 monoclonal antibody and activated B cells as costimulatory-signal-providing cells.: Cancer Immunol Immunother. 1995 Mar;40(3):173-81. Unique Identifier : AIDSLINE MED/95246049; Okamoto T; Harada M; Shinomiya Y; Matsuzaki G; Nomoto K; Department of Immunology, Kyushu University, Fukuoka, Japan.; To establish an efficient cell-culture system for adoptive immunotherapy, we attempted to use lipopolysaccharide(LPS)-activated B cells (LPS blasts) as costimulatory-signal-providing cells in the in vitro induction of antitumor effector cells. Both normal and tumor-draining lymph node cells were efficiently activated
Viral infections: musculoskeletal infection in the human immunodeficiency virus (HIV) infected patient.: Baillieres Clin Rheumatol. 1995 Feb;9(1):121-32. Unique Identifier : AIDSLINE MED/95246149; Jellis JE; University of Zambia, School of Medicine, Lusaka.; HIV disease has reached epidemic proportions in Africa over the last decade and is severely stretching the health services of the many poor countries of the region. Increased sepsis during fracture surgery and the late infection of implants impels us to rethink many standard methods of treatment. Musculoskeletal infec
Viral infections: arthritis in the human immunodeficiency virus (HIV) infected patient.: Baillieres Clin Rheumatol. 1995 Feb;9(1):133-44. Unique Identifier : AIDSLINE MED/95246150; Morrison E; McGill PE; Jellis JE; Department of Rheumatology, Stobhill Hospital NHS Trust, Glasgow,; UK.; Reactive arthritis is common in HIV-positive patients and may be mistaken for septic arthritis. We feel that the association is probably, in part, due to the increased incidence of diarrhoeal diseases in HIV-infected patients rather than a specific effect of HIV on the synovium. Disabling, chronic, sero-negative polya
Bacterial infections: bone and joint tuberculosis.: Baillieres Clin Rheumatol. 1995 Feb;9(1):151-9. Unique Identifier : AIDSLINE MED/95246152; Jellis JE; University of Zambia, School of Medicine, Lusaka.; In many countries of the world, there is now a dual epidemic of tuberculosis and HIV disease. HIV specifically eliminates the tissue macrophages and CD4 lymphocytes, the very cells that provide immunity against tuberculosis. Tuberculosis is one of the more virulent opportunistic infections and it therefore appears fai
Bacterial infections: pyomyositis.: Baillieres Clin Rheumatol. 1995 Feb;9(1):193-200. Unique Identifier : AIDSLINE MED/95246155; McGill PE; Stobhill Hospital NHS Trust, Glasgow, UK.; Staphylococcal pyomyositis is an important and common condition in many areas in the tropics. The cause is probably multifactorial and includes damage to the skeletal muscle in the presence of staphylococcal bacteraemia, with or without depressed immunity. In Africa, there are indications of an increased prevalence in
Rheumatoid arthritis and connective tissue disorders: sub-Saharan Africa.: Baillieres Clin Rheumatol. 1995 Feb;9(1):31-44. Unique Identifier : AIDSLINE MED/95246160; Mody GM; Department of Medicine, University of Natal, Durban, South; Africa.; Rheumatoid arthritis (RA) once a rarity in Africa, is now reported in large numbers from many parts of Africa. Although epidemiological surveys have shown that the prevalence in urban populations is similar to Western communities, it is less common in rural areas. Further epidemiological studies are needed to confirm
The spondyloarthropathies.: Baillieres Clin Rheumatol. 1995 Feb;9(1):95-109. Unique Identifier : AIDSLINE MED/95246166; Richens J; McGill PE; Academic Department of Genitourinary Medicine, University College; London Medical School, UK.; The spondyloarthropathies occur with variable frequency in the tropics. Ankylosing spondylitis, in particular, is thought to be rare in tropical Africa, reflecting a low frequency of the HLA B27 gene. However, in the Melanesian populations of
DNA polymerase action on an oligonucleotide containing a site-specifically located N-(deoxyguanosin-8-yl)-1-aminopyrene.: Carcinogenesis. 1995 Apr;16(4):811-6. Unique Identifier : AIDSLINE MED/95246240; Vyas RR; Basu AK; Department of Chemistry, University of Connecticut, Storrs 06269,; USA.; A 25mer oligonucleotide containing a single N-(deoxyguanosin-8-yl-)-1-aminopyrene (dGAP), the major DNA adduct formed by reductively activated 1-nitropyrene, was synthesized. The adduct was located at nucleotide 21 from the 3 end. DNA synthesis on this template by human DNA polymerases alpha and beta, HIV reverse tra
Herpes simplex virus brainstem encephalitis in an AIDS patient.: Clin Neuropathol. 1995 Jan-Feb;14(1):45-50. Unique Identifier : AIDSLINE MED/95246369; Hamilton RL; Achim C; Grafe MR; Fremont JC; Miners D; Wiley CA; University of California, San Diego, Department of Pathology; (Neuropathology), La Jolla, USA.; We report a case of a virulent, atypical herpes simplex infection in the brainstem of a patient with Acquired Immune Deficiency Syndrome (AIDS) which was characterized by demyelination and oligodendroglial tropism. At autopsy the brainstem showed demyelination. Immunocytochemistry, in situ hybridization, and electron
Cerebral toxoplasmosis in a patient with the acquired immunodeficiency syndrome presenting as obstructive hydrocephalus.: Clin Neuropathol. 1995 Jan-Feb;14(1):51-4. Unique Identifier : AIDSLINE MED/95246370; Eggers C; Vortmeyer A; Emskotter T; Abteilung fur Neurologie, Universitatsklinik Hamburg-Eppendorf,; Germany.; We report the case of an adult AIDS-patient with an unusual pattern of toxoplasmic encephalitis resembling the congenital form of the disease. Extensive exudative ependymitis and plexitis caused obstruction of internal CSF-pathways with rapid development of hydrocephalus. CT showed hydrocephalus and multifocal hypoden
[Sensory disturbance due to radiculopathy (letter)]: Rinsho Shinkeigaku. 1994 Nov;34(11):1175. Unique Identifier : AIDSLINE MED/95246391; Kishi Y
[Migrating radiculopathy--an unusual complication of systemic lupus erythematosus in an HTLV-1 carrier (letter)]: Rinsho Shinkeigaku. 1994 Nov;34(11):1176. Unique Identifier : AIDSLINE MED/95246392; Kondo T; Matsui M
A histological basis for the 'sonographic snowstorm' in opportunistic infection of the liver and spleen.: Clin Radiol. 1995 Apr;50(4):220-2. Unique Identifier : AIDSLINE MED/95246406; Keane MA; Finlayson C; Joseph AE; Department of Diagnostic Radiology, St George's Hospital, London.; We report 3 cases of opportunistic infection of the liver and spleen due to Pneumocystis carinii, Candida albicans and Aspergillus with an unusual but similar sonographic appearance. In the patient with Pneumocystis we report for the first time this same appearance in the bowel and pleura. Histology showed either exte
Disseminated histoplasmosis presenting as tongue nodules in a patient infected with human immunodeficiency virus.: Cutis. 1995 Feb;55(2):104-6. Unique Identifier : AIDSLINE MED/95246445; Cole MC; Grossman ME; Department of Dermatology, College of Physicians and Surgeons of; Columbia University, New York, New York, USA.; A 39-year-old woman infected with human immunodeficiency virus had disseminated histoplasmosis that presented with nodules on her tongue. This is the seventh reported case of biopsy- and/or culture-proven oropharyngeal histoplasmosis in patients with acquired immunodeficiency syndrome. We review those previous reports
Photodistributed hypertrophic lichen planus in association with acquired immunodeficiency syndrome: a distinct entity.: Cutis. 1995 Feb;55(2):109-11. Unique Identifier : AIDSLINE MED/95246446; Fitzgerald E; Purcell SM; Goldman HM; Department of Dermatology, Philadelphia College of Osteopathic; Medicine, Pennsylvania, USA.; The cutaneous manifestations of human immunodeficiency virus infection include papulosquamous diseases, viral and fungal infections, and neoplastic disorders. Eczematous photosensitivity disorders have been reported in patients infected with the human immunodeficiency virus. We describe a patient with advanced acquire
Papular mucinosis and human immunodeficiency virus infection.: Cutis. 1995 Feb;55(2):113-4. Unique Identifier : AIDSLINE MED/95246447; Biro DE; Lynfield YC; Heilman ER; Department of Dermatology, State University of New York, Brooklyn; 11203, USA.; Cutaneous mucin deposition occurs both as an isolated phenomenon and in patients with various systemic disorders. Among these are endocrinopathies (eg, hypo- and hyperthyroidism), malignancy (mycosis fungoides), connective tissue disorders (lupus erythematosus), and infectious diseases (scleredema associated with uppe
Special issue: AIDS in dermatology.: Cutis. 1995 Feb;55(2):60-114. Unique Identifier : AIDSLINE MED/95246448
Cutaneous manifestations of childhood acquired immunodeficiency syndrome and human immunodeficiency virus infection.: Cutis. 1995 Feb;55(2):62-6, 70-2. Unique Identifier : AIDSLINE MED/95246450; Whitworth JM; Janniger CK; Oleske JM; Schwartz RA; UMD-New Jersey Medical School, Newark 07103-2714, USA.
The human immunodeficiency virus.: Cutis. 1995 Feb;55(2):81-3. Unique Identifier : AIDSLINE MED/95246452; Wheeler DA; Department of Medicine, University of Maryland School of; Medicine, Baltimore 21201, USA.; Infection with the human immunodeficiency virus is now a worldwide pandemic, transmitted through contact with infected body fluids, particularly during heterosexual intercourse. Infection in adults is followed by an asymptomatic period that lasts several years, after which continued destruction of the immune system re
Fundamental basic science of human immunodeficiency virus.: Cutis. 1995 Feb;55(2):84. Unique Identifier : AIDSLINE MED/95246453; Burnett JW; University of Maryland, Department of Dermatology, Baltimore; 21201, USA.
Cutaneous diseases in human immunodeficiency virus-infected patients referred to the UCLA Immunosuppression Skin Clinic: reasons for referral and management of select diseases.: Cutis. 1995 Feb;55(2):85-8, 93-8. Unique Identifier : AIDSLINE MED/95246454; Dann FJ; Tabibian P; Division of Dermatology, UCLA School of Medicine, USA.; Many nondermatologist physicians have become skilled at identifying and treating certain human immunodeficiency virus-related skin diseases. They are reserving referrals primarily for diagnostically or therapeutically challenging skin disorders. Our purpose was to study the reasons for referral of human immunodeficien
[Optimal conditions of gamma type irradiation for inactivating HIV in bone fragments. Consequences in biomechanical resistance of the bone tissue]: Chirurgie. 1994-95;120(2):104-6. Unique Identifier : AIDSLINE MED/95246509; Tosello A; Centre Regional de Transfusion Sanguine, Marseille.; In order to determine bone-dependent penetration differences, we conducted a dosimetric study of gamma radiation using 2.5 mega rads on cancellous bone fragments at 4 degrees C and below 0 degrees with or without a surrounding solution. Variations in dose received inside and outside the femoral head were independent o
Use of thalidomide in treatment and maintenance of idiopathic esophageal ulcers in HIV+ individuals.: Dig Dis Sci. 1995 May;40(5):1147-8. Unique Identifier : AIDSLINE MED/95246572; Naum SM; Molloy PJ; Kania RJ; McGarr J; Van Thiel DH; Division of Gastroenterology, Western Pennsylvania Hospital,; Pittsburgh, USA.
Extrinsic tracheal compression--a newly described complication of acquired immune deficiency syndrome (AIDS).: Ear Nose Throat J. 1995 Mar;74(3):189-92. Unique Identifier : AIDSLINE MED/95246642; Patete ML; Mellon D; Department of Otolaryngology, Head and Neck Surgery, University; of Miami/Jackson Memorial Hospital, Florida 33026, USA.; An AIDS patient was seen in respiratory difficulty with a superior mediastinal mass. Examination revealed a candida fungoma. To the best of our knowledge, this is the only case of its nature. The differential diagnosis and management of this patient are presented in detail.
Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes.: EMBO J. 1995 Apr 3;14(7):1552-60. Unique Identifier : AIDSLINE MED/95246748; Alcami J; Lain de Lera T; Folgueira L; Pedraza MA; Jacque JM; Bachelerie F; Noriega AR; Hay RT; Harrich D; Gaynor RB; et al; Servicio de Microbiologia, Hospital 12 de Octubre, Madrid,; Spain.; The role of NF-kappa B-dependent signals in activating the transcriptional activity of the HIV regulatory region (LTR) was analyzed by systematic comparison of HIV LTR activity in human CD4 T cells purified from peripheral blood and a transformed lymphoblastoid T cell line. In normal CD4 T cells we also analyzed the r
Nasopharyngeal carriage of Staphylococcus aureus and carriage of tetracycline-resistant strains associated with HIV-seropositivity.: Eur J Clin Microbiol Infect Dis. 1995 Jan;14(1):34-40. Unique Identifier : AIDSLINE MED/95246769; Amir M; Paul J; Batchelor B; Kariuki S; Ojoo J; Waiyaki P; Gilks C; Wellcome Trust Research Laboratories, Kilifi, Kenya.; The aim of this prospective study was to investigate the relationship between carriage of antibiotic-resistant Staphylococcus aureus and infection with the human immunodeficiency virus (HIV). A total of 554 pernasal swabs was taken during a six-month period from 554 adult patients attending three outpatient clinics an
Evaluation of the optimal number of faecal specimens in the diagnosis of cryptosporidiosis in AIDS and immunocompetent patients.: Eur J Clin Microbiol Infect Dis. 1995 Jan;14(1):46-9. Unique Identifier : AIDSLINE MED/95246772; Clavel A; Arnal AC; Sanchez EC; Varea M; Castillo FJ; Ramirez de Ocariz I; Quilez J; Cuesta J; Servicio de Microbiologia y Parasitologia, Hospital Clinico; Universitario, Zaragoza, Spain.; This study determines the optimal number of faecal samples that should be examined in order to minimize the occurrence of false-negative results in the diagnosis of cryptosporidiosis using routine techniques. A total of 23,023 faecal samples from 10,870 patients submitted for parasitological examination were processed
HIV epidemic in Punjab.: Indian J Med Res. 1995 Feb;101:47-9. Unique Identifier : AIDSLINE MED/95247219; Sehgal S; Department of Immunopathology, Postgraduate Institute of Medical; Education & Research, Chandigarh.; A total of 58890 subjects were screened for HIV infection between June 1987 to December 1992. Out of these, 42776 were blood donors and only 9 were positive for HIV by ELISA; 2749 were foreign students and 35 were confirmed positive both by ELISA and Western blot. Out of the remaining high risk subjects, 141 of 13365
Intestinal and hepatobiliary diseases in HIV-infected children.: Gastroenterol Clin North Am. 1995 Mar;24(1):119-32. Unique Identifier : AIDSLINE MED/95247229; Lewis JD; Winter HS; Massachusetts General Hospital, Children's Hospital, Boston, USA.; Children with HIV disease and gastrointestinal disease should be evaluated for enteric pathogens. Bacterial, protozoal, and viral agents can cause chronic diarrhea, abdominal pain, gastrointestinal bleeding, and contribute to growth retardation. This article presents an approach to the evaluation of the HIV-infected c
Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis.: Infect Immun. 1995 May;63(5):1784-9. Unique Identifier : AIDSLINE MED/95247261; Cain TK; Rank RG; Department of Microbiology and Immunology, University of Arkansas; for Medical Sciences, Little Rock 72205, USA.; A critical role for cell-mediated immunity (CMI) has been demonstrated for effecting the resolution of genital infections of mice infected intravaginally with the mouse pneumonitis biovar of Chlamydia trachomatis (MoPn). However, little is known about expression of CMI in the murine genital tract. The mouse MoPn model
Regulation of macrophage activation and human immunodeficiency virus production by invasive Salmonella strains.: Infect Immun. 1995 May;63(5):1820-6. Unique Identifier : AIDSLINE MED/95247267; Mizel SB; Kucera LS; Richardson SH; Ciacci F; Iyer NP; Department of Microbiology and Immunology, Wake Forest University; Medical Center, Winston-Salem, North Carolina 27157, USA.; Salmonellae possess the ability to adhere to and invade macrophages and in so doing trigger a number of intracellular events that are associated with cellular activation. As an initial approach to defining the mechanisms by which invasive salmonellae alter macrophage function, we have explored the impact of Salmonella
Cellular immune response to Mycobacterium leprae infection in human immunodeficiency virus-infected individuals.: Infect Immun. 1995 May;63(5):1848-54. Unique Identifier : AIDSLINE MED/95247271; Sampaio EP; Caneshi JR; Nery JA; Duppre NC; Pereira GM; Vieira LM; Moreira AL; Kaplan G; Sarno EN; Leprosy Department, Oswaldo Cruz Foundation, Manguinhos, Rio de; Janeiro, Brazil.; The immune responses to Mycobacterium leprae and other mycobacterial antigens were studied in 11 leprosy patients with concurrent human immunodeficiency virus type 1 (HIV-1) infection. Three patients manifested borderline lepromatous leprosy, and eight patients had borderline tuberculoid (BT) leprosy. Despite the low
Impact of antigen-presenting cells on cytokine profiles of human Th clones established after stimulation with Mycobacterium tuberculosis antigens.: Infect Immun. 1995 May;63(5):2079-81. Unique Identifier : AIDSLINE MED/95247305; Conradt P; Kaufmann SH; Department of Immunology, University of Ulm, Germany.; Human T cells reactive with mycobacterial antigens are generally considered to correlate with a Th1 cytokine profile. Our data show that, in addition, Th0 and Th2 clones develop in bulk culture with appropriate antigen-presenting cells before cloning. CD4+ blasts activated by mycobacterial antigens were cloned, and th
High frequency of EBV association with non-random abnormalities of the chromosome region 1q21-25 in AIDS-related Burkitt's lymphoma-derived cell lines.: Int J Cancer. 1995 May 4;61(3):370-4. Unique Identifier : AIDSLINE MED/95247332; Polito P; Cilia AM; Gloghini A; Cozzi M; Perin T; De Paoli P; Gaidano G; Carbone A; Division of Pathology, Istituto Nazionale di Ricovero e Cura a; Carattere Scientifico, Aviano, Italy.; Chromosome 1q abnormalities represent the second most frequent cytogenetic lesion of Burkitt lymphoma (BL) and acute lymphoblastic leukemia (ALL)-L3. The most frequent change is partial duplication of the long arm of chromosome 1, involving variable bands but consistently including 1q23. Among AIDS-related BL similar
Induction and characterization of cytotoxic T-lymphocytes recognizing a mutated p21ras peptide presented by HLA-A*0201.: Int J Cancer. 1995 May 4;61(3):389-96. Unique Identifier : AIDSLINE MED/95247335; Van Elsas A; Nijman HW; Van der Minne CE; Mourer JS; Kast WM; Melief CJ; Schrier PI; Department of Clinical Oncology, University Hospital, Leiden, The; Netherlands.; The ras oncogene is frequently found to be activated in human cancer through point mutations at codons 12, 13 or 61. We explored whether these altered p21ras protein sequences contain peptide sequences that can activate naive CD8+ cytotoxic T lymphocytes (CTL). Several wild-type and mutated p21ras peptides were identi
The role of organized labor in combating the hepatitis B and AIDS epidemics: the fight for an OSHA bloodborne pathogens standard.: Int J Health Serv. 1995;25(1):129-52. Unique Identifier : AIDSLINE MED/95247348; Muraskin WA; The United States is experiencing a hepatitis B epidemic that has until recently received relatively little public attention. Many groups of workers are at risk of infection, death, or chronic carriership because of workplace exposure to blood; those at risk include not only health car
Effectiveness of health instruction provided by student nurses in rural secondary schools of Zimbabwe: a feasibility study.: Int J Nurs Stud. 1995 Feb;32(1):27-38. Unique Identifier : AIDSLINE MED/95247389; Munodawafa D; Marty PJ; Gwede C; University of Akron, Department of Physical and Health Education,; OH 44325-5103, USA.; This demonstration project used student nurses (n = 12) on community deployment to provide health instruction among rural school-age populations in Zimbabwe . A quasi-experimental (pre- and post-test), non-equivalent control group design was used and consisted of 141 school pupils
Norplant and irresponsible reproduction.: Hastings Cent Rep. 1995 Jan-Feb;25(1):S23-6. Unique Identifier : AIDSLINE MED/95247436; Robertson JA; University of Texas, Austin, USA.
Use of echocardiography to detect tumors in the heart of a bull with bovine leukosis.: J Am Vet Med Assoc. 1994 Dec 1;205(11):1590-2. Unique Identifier : AIDSLINE MED/95247532; Schmitz DG; Seahorn TL; Department of Veterinary Large Animal Medicine and Surgery,; College of Veterinary Medicine, Texas A&M University, College; Station 77843-4475.; Echocardiography was valuable in identifying tumorous growth in the cardiac tissues of a bull with enzootic bovine leukosis. The tumor was discernable as a thickening of the interatrial septum and wall of the right atrium, accompanied by an immobile pedunculated mass that originated from the interatrial septum and ext
Interleukin-12 augments the generation of autologous tumor-reactive CD8+ cytotoxic T lymphocytes from tumor-infiltrating lymphocytes.: Jpn J Cancer Res. 1995 Feb;86(2):135-9. Unique Identifier : AIDSLINE MED/95247536; Kuge S; Watanabe K; Makino K; Tokuda Y; Mitomi T; Kawamura N; Habu S; Nishimura T; Department of Immunology, Tokai University School of Medicine,; Isehara.; Human tumor-infiltrating lymphocytes (TIL) were obtained from breast cancer, renal cancer or neuroblastoma to investigate the generation of autologous tumor-reactive CD8+ cytotoxic T lymphocytes (CTL). When TIL were cultured with interleukin (IL)-2 (100 U/ml), the growth of TIL peaked around 8-10 days after the initia
Total structures and antimicrobial activity of bacitracin minor components.: J Antibiot (Tokyo). 1995 Mar;48(3):233-42. Unique Identifier : AIDSLINE MED/95247559; Ikai Y; Oka H; Hayakawa J; Matsumoto M; Saito M; Harada K; Mayumi Y; Suzuki M; Aichi Prefectural Institute of Public Health, Nagoya, Japan.; Total structures of 13 minor components of bacitracin (BC) were proposed, and their antimicrobial activities were investigated. The components of BC including bacitracins A (BC-A) and F (BC-F) were isolated by preparative HPLC and were hydrolyzed under acidic conditions. The resulting amino aids were derivatized with
Synergic inhibitory activity of amphotericin-B and gamma interferon against intracellular Cryptococcus neoformans in murine macrophages.: J Antimicrob Chemother. 1994 Dec;34(6):1051-8. Unique Identifier : AIDSLINE MED/95247623; Herrmann JL; Dubois N; Fourgeaud M; Basset D; Lagrange PH; Laboratoire de Microbiologie, Hopital Hotel Dieu, Paris, France.; Cryptococcus neoformans is responsible for pulmonary and meningal infections in HIV patients. The lack of effective cellular cooperation caused by the low level of CD4+ cells, and the resistance of C. neoformans to phagocytosis allows growth and persistence of the yeast in the host. We describe here an in-vitro model
Intraphagocytic killing of gram-positive bacteria by ciprofloxacin.: J Antimicrob Chemother. 1994 Dec;34(6):965-74. Unique Identifier : AIDSLINE MED/95247641; Peman J; Canton E; Hernandez MT; Gobernado M; Servicio de Microbiologia, Hospital Universitario La Fe,; Valencia, Spain.; The intraphagocytic killing of Staphylococcus aureus, Streptococcus pyogenes, and Corynebacterium group D2 by ciprofloxacin (0.1, 1 and 5 mg/L) within human neutrophils was determined. The organisms showed different susceptibility to neutrophil killing mechanisms. The neutrophils with intact and impaired (by phenylbut
Stimulation of HIV expression by intracellular calcium pump inhibition.: J Biol Chem. 1995 Apr 28;270(17):10278-83. Unique Identifier : AIDSLINE MED/95247739; Papp B; Byrn RA; Hematology-Oncology Research Laboratory, Deaconess Hospital,; Harvard Medical School, Boston, Massachusetts 02215, USA.; We have studied the role of intracellular calcium sequestration on human immunodeficiency virus (HIV) production by latently infected T-lymphocytic cells. Inhibition of the sarco-endoplasmic reticulum-type calcium transport ATPases by thapsigargin or cyclopiazonic acid induced activation of HIV production in the CEM-d
Evaluation of an agglutination HIV-1 + 2 antibody assay.: J Virol Methods. 1995 Jan;51(1):1-8. Unique Identifier : AIDSLINE MED/95247861; Vercauteren G; Beelaert G; van der Groen G; Institute of Tropical Medicine, Department of Microbiology,; Antwerp, Belgium.; Studies have shown that an HIV (HIV-PA) agglutination assay (Serodia) for the detection of antibody to human immunodeficiency virus (HIV) can be as sensitive and as specific as enzyme-linked immunosorbent assay (ELISA). However, since this HIV assay was designed to detect antibody to the HIV-1 virus, a substantial num
Identification of HTLV-I- or HTLV-II-producing cells by cocultivation with BHK-21 cells stably transfected with a LTR-lacZ gene construct.: J Virol Methods. 1995 Jan;51(1):19-29. Unique Identifier : AIDSLINE MED/95247866; Astier-Gin T; Portail JP; Lafond F; Guillemain B; INSERM Unite 328, Bordeaux, France.; The Syrian Hamster kidney cell line (BHK-21) was stably transfected with a plasmid vector containing the lacZ bacterial gene under the control of a HTLV-I-LTR promoter. In these cells termed pA18G-BHK-21, this lacZ construct is inducible by the tax protein produced by a tax expression vector. It was also shown that be
Typing human T-cell lymphotropic virus (HTLV-I and HTLV-II) by nested polymerase chain reaction: application to clinical specimens.: J Virol Methods. 1995 Jan;51(1):9-17. Unique Identifier : AIDSLINE MED/95247873; Vallejo A; Garcia-Saiz A; Servicio de Diagnostico y Referencia, Instituto de Salud Carlos; III, Madrid, Spain.; Human T-cell lymphotropic virus type I and II provirus DNA was detected by polymerase chain reaction (PCR). MT-2 (HTLV-I infected), C3/44 Mo (HTLV-II infected) cell lines and peripheral blood mononuclear cells (PBMNC) from HTLV seropositive samples were used. The procedure consists of first amplification which detects
Internal quality assurance in a clinical virology laboratory. II. Internal quality control.: J Clin Pathol. 1995 Mar;48(3):198-202. Unique Identifier : AIDSLINE MED/95247915; Gray JJ; Wreghitt TG; McKee TA; McIntyre P; Roth CE; Smith DJ; Sutehall G; Higgins G; Geraghty R; Whetstone R; et al; Clinical Microbiology and Public Health Laboratory, Addenbrooke's; Hospital, Cambridge.; AIMS--In April 1991 additional quality control procedures were introduced into the virology section of the Clinical Microbiology and Public Health Laboratory, Cambridge. Internal quality control (IQC) samples were gradually included in the serological assays performed in the laboratory and supplemented kit controls an
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.: J Immunol. 1995 May 15;154(10):5071-9. Unique Identifier : AIDSLINE MED/95248071; Macatonia SE; Hosken NA; Litton M; Vieira P; Hsieh CS; Culpepper JA; Wysocka M; Trinchieri G; Murphy KM; O'Garra A; Department of Immunology, DNAX Research Institute of Molecular; and Cellular Biology Inc., Palo Alto, CA 94303, USA.; Dendritic cells are APCs that are unique in their potency to stimulate proliferation of primary Ag-specific responses in vitro and in vivo. In this study, we demonstrate that dendritic cells can produce IL-12, a dominant cytokine involved in the development of IFN-gamma-producing T cells. This finding resulted from ou
Synergistic effects of IL-7 and IL-12 on human T cell activation.: J Immunol. 1995 May 15;154(10):5093-102. Unique Identifier : AIDSLINE MED/95248073; Mehrotra PT; Grant AJ; Siegel JP; Laboratory of Cellular Immunology, Food and Drug Administration,; Rockville, MD 20852, USA.; We have previously demonstrated that human rIL-12 alone can augment the development of cytotoxic activity in stimulated CD8+ T cells. The present study was undertaken to examine the interactions of rIL-7 and rIL-12 on human peripheral blood T cell activation and CTL differentiation. Purified T lymphocytes were pulsed
Growth inhibition of Candida albicans hyphae by CD8+ lymphocytes.: J Immunol. 1995 May 15;154(10):5273-81. Unique Identifier : AIDSLINE MED/95248093; Beno DW; Stover AG; Mathews HL; Department of Microbiology and Immunology, Stritch School of; Medicine, Loyola University of Chicago, Maywood, IL 60153, USA.; We have shown previously that IL-2-activated splenocytes can inhibit the growth of Candida albicans hyphae in vitro. Herein we demonstrate that plastic nonadherent lymphocytes that are CD8+ mediate the antifungal activity. Enrichment for CD8+ cells markedly enhanced the antifungal activity of the IL-2-activated lympho
IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis.: J Immunol. 1995 May 15;154(10):5320-30. Unique Identifier : AIDSLINE MED/95248098; Scharton-Kersten T; Afonso LC; Wysocka M; Trinchieri G; Scott P; Department of Pathobiology, University of Pennsylvania, School of; Veterinary Medicine, Philadelphia 19104, USA.; Infection of mice with the protozoan Leishmania major is an established in vivo model for the definition of factors that contribute to CD4+ T helper cell subset development. In the current study, a central role for IL-12 in directing both the innate and adaptive immune responses to L. major is established. We show tha
Effects of stress on immune cell distribution. Dynamics and hormonal mechanisms.: J Immunol. 1995 May 15;154(10):5511-27. Unique Identifier : AIDSLINE MED/95248119; Dhabhar FS; Miller AH; McEwen BS; Spencer RL; Laboratory of Neuroendocrinology, Rockefeller University, New; York, NY 10021, USA.; Immune cell trafficking is crucial to the performance of the surveillance as well as effector functions of the immune system. Because immune cells travel between tissues through the bloodstream, the numbers and proportions of leukocytes in the circulation provide an important representation of the state of leukocyte d
Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden.: J Immunol. 1995 May 15;154(10):5555-66. Unique Identifier : AIDSLINE MED/95248123; Muro-Cacho CA; Pantaleo G; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892, USA.; The occurrence of in vivo apoptosis was investigated in lymph node sections obtained from HIV-infected persons at different stages of disease. The degree of apoptosis in lymph nodes from HIV-infected individuals was compared with that observed in lymph nodes obtained from HIV-negative individuals. Apoptosis was readil
Simian immunodeficiency virus (SIV)-specific CTL in cerebrospinal fluid and brains of SIV-infected rhesus macaques.: J Immunol. 1995 May 15;154(10):5582-9. Unique Identifier : AIDSLINE MED/95248126; von Herrath M; Oldstone MB; Fox HS; Department of Neuropharmacology, Scripps Research Institute, La; Jolla, CA 92037, USA.; Simian immunodeficiency virus (SIV)-specific CD8+ CTL were isolated from blood, cerebrospinal fluid, and brains of rhesus macaques infected i.v. with SIV. CTL were found as early as 1 wk postinfection and their appearance correlated with a decrease of viral Ag (p27) found in the blood. CTL isolated from cerebrospinal
Early detection of apoptosis in defined lymphocyte populations in vivo.: J Immunol Methods. 1995 Apr 12;181(1):17-27. Unique Identifier : AIDSLINE MED/95248133; Zhang L; Wang C; Radvanyi LG; Miller RG; Ontario Cancer Institute, Toronto, Canada.; Recently many methods have been developed for the detection of apoptosis. However, all of them have some limitations in determining whether specific subsets of cells are undergoing apoptosis. In this paper we describe a technique in which one simultaneously stains for cell surface markers with fluorescent monoclonal a
The humanized severe combined immunodeficient mouse as a model for primary human humoral response against HIV1 peptides.: J Immunol Methods. 1995 Apr 12;181(1):91-100. Unique Identifier : AIDSLINE MED/95248141; Chargui J; Dye D; Blomberg J; Desgranges C; Touraine JL; INSERM U80, Hopital Edouard Herriot, Lyon, France.; Adequate animal models for the study of human immunodeficiency virus (HIV) infection are important for the analysis of specific cellular and humoral immune responses. Humanized severe combined immunodeficiency (SCID) mice can be constructed either by injecting human peripheral blood lymphocytes (hu-PBL-SCID) or by tra
Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS.: J Pain Symptom Manage. 1995 Feb;10(2):89-97. Unique Identifier : AIDSLINE MED/95248169; Beal JE; Olson R; Laubenstein L; Morales JO; Bellman P; Yangco B; Lefkowitz L; Plasse TF; Shepard KV; St. John's Hospital, Tulsa, Oklahoma, USA.; The effects of dronabinol on appetite and weight were evaluated in 139 patients with AIDS-related anorexia and > or = 2.3 kg weight loss in a multi-institutional study. Patients were randomized to receive 2.5 mg dronabinol twice daily or placebo. Patients rated appetite, mood, and nausea by using a 100-mm visual analo
Lesbian health issues for the primary care provider [see comments]: J Fam Pract. 1995 May;40(5):486-96. Unique Identifier : AIDSLINE MED/95248255; Rankow EJ; Duke University Medical Center, Durham, North Carolina, USA.; Lesbians have unique health concerns that often go unaddressed in a medical setting that assumes heterosexuality. These may include cancer screening, sexually transmitted diseases, human immunodeficiency virus (HIV), depression, substance abuse, relationship issues, pregnancy, and parenting. Awareness of the barriers
CD4 expression on dendritic cells and their infection by human immunodeficiency virus.: J Gen Virol. 1995 May;76 ( Pt 5):1155-63. Unique Identifier : AIDSLINE MED/95248283; Patterson S; Gross J; English N; Stackpoole A; Bedford P; Knight SC; Antigen Presentation Research Group, Clinical Research Centre,; Harrow, Middlesex, UK.; Infection of dendritic cells (DC) by human immunodeficiency virus (HIV) has been disputed. Employing a fluorescence-activated cell sorter, DC, identified by the absence of membrane markers for T, B, natural killer (NK) and monocytic cells and by high levels of MHC class II DR antigen, were shown to express low levels
An index of symptoms for infection with human immunodeficiency virus: reliability and validity.: J Clin Epidemiol. 1994 May;47(5):537-46. Unique Identifier : AIDSLINE MED/95248364; Whalen CC; Antani M; Carey J; Landefeld CS; Cleveland Veterans Affairs Medical Center, OH 44106, USA.; The objective of this study was to evaluate the reliability and validity of a brief index to measure symptoms in individuals infected with human immunodeficiency virus (HIV). From an ambulatory clinic that specializes in the care of HIV-infected individuals at a university hospital in northeast Ohio, 148 randomly sele
Access to therapy in the Multicenter AIDS Cohort Study, 1989-1992.: J Clin Epidemiol. 1994 Sep;47(9):1003-12. Unique Identifier : AIDSLINE MED/95248387; Graham NM; Jacobson LP; Kuo V; Chmiel JS; Morgenstern H; Zucconi SL; Department of Epidemiology, Johns Hopkins University, School of; Hygiene and Public Health, Baltimore, MD 21205, USA.; The study aims were (i) to describe secular trends in the utilization of antiretrovirals, antivirals, Pneumocystis carinii pneumonia (PCP) prophylaxis, and antifungal prophylaxis and (ii) to determine whether factors such as clinical status, health services utilization, insurance status, income, education and race wer
Receipt of recommended medical care in HIV-infected and at-risk persons.: J Gen Intern Med. 1995 Feb;10(2):92-5. Unique Identifier : AIDSLINE MED/95248433; Marx R; Katz MH; Barreto AI; Park MS; Black T; Welch M; AIDS Office, Department of Public Health, San Francisco,; California 94102-6033, USA.; The authors evaluated receipt of recommended medical care for 133 HIV-infected and 101 at-risk San Francisco public health clinic patients. Fewer than half the patients received syphilis and tuberculosis screening, hepatitis B immunity testing or vaccination, and tetanus boosters. The HIV-infected persons were signifi
Clinical aspects of HIV infection in women.: J Gen Intern Med. 1995 Feb;10(2):99-110. Unique Identifier : AIDSLINE MED/95248435; Coodley GO; Coodley MK; Thompson AF; Division of Internal Medicine, Oregon Health Sciences University,; Portland 97201, USA.
Synthesis and in vivo evaluation of prodrugs of 9-[2-(phosphonomethoxy)ethoxy]adenine.: J Med Chem. 1995 Apr 14;38(8):1372-9. Unique Identifier : AIDSLINE MED/95248518; Serafinowska HT; Ashton RJ; Bailey S; Harnden MR; Jackson SM; Sutton D; SmithKline Beecham Pharmaceuticals, Epsom, Surrey, U.K.; A number of esters and amides of the anti-HIV nucleotide analogue 9-[2-(phosphonomethoxy)-ethoxy]adenine (1) have been synthesized as potential prodrugs and evaluated for oral bioavailability in mice. Dialkyl esters 17-20 were prepared via a Mitsunobu coupling of alcohols 8-11 with 9-hydroxypurine 12 whereas (acyloxy)
Synthesis, absolute configuration, and enantioselectivity of antiretroviral effect of (R)-(-)- and (S)-(+)-cytallene. Lipase-catalyzed enantioselective acylations of (+/-)-N4-acylcytallenes.: J Med Chem. 1995 Apr 14;38(8):1397-405. Unique Identifier : AIDSLINE MED/95248521; Jones BC; Silverton JV; Simons C; Megati S; Nishimura H; Maeda Y; Mitsuya H; Zemlicka J; Department of Chemistry, Michigan Cancer Foundation, Wayne State; University School of Medicine, Detroit 48201, USA.; Enantioselectivity of acylations of (+/-)-cytallene (1b), (+/-)-N4-acetylcytallene (11a), (+/-)-N4-benzoylcytallene (11b), and (+/-)-N4-(9-fluorenylmethoxycarbonyl)cytallene (11c) using vinyl butyrate or acetate catalyzed by lipases in organic solvents was investigated. Reactions with 1b, 11a, and adenallene (1a) did
Intrarectal inoculation of macaques by the simian immunodeficiency virus, SIVmne E11S: CD4+ depletion and AIDS.: J Med Primatol. 1994 Sep;23(7):397-409. Unique Identifier : AIDSLINE MED/95248529; Kuller L; Benveniste RE; Tsai CC; Clark EA; Polacino P; Watanabe R; Overbaugh J; Katze MG; Morton WR; Regional Primate Research Center, University of Washington,; Seattle 98195, USA.; Macaca nemestrina and Macaca fascicularis were inoculated with various doses of a single-cell clone of SIVmne-infected HuT 78 cells (E11S) by both the intravenous and intrarectal routes. Animals inoculated intravenously at each dose seroconverted and virus was isolated from peripheral blood mononuclear cells, but only
How HIV causes AIDS [letter]: J Natl Med Assoc. 1995 Mar;87(3):171, 173. Unique Identifier : AIDSLINE MED/95248568; Spartalis MA
Clinical differences between pulmonary and extrapulmonary tuberculosis: a 5-year retrospective study.: J Natl Med Assoc. 1995 Mar;87(3):187-92. Unique Identifier : AIDSLINE MED/95248571; Antony SJ; Harrell V; Christie JD; Adams HG; Rumley RL; Department of Medicine, East Carolina University School of; Medicine, Greenville, North Carolina, USA.; This article describes the clinical, epidemiologic, laboratory, and treatment characteristics of pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) in Eastern North Carolina, a primarily rural area. The database was obtained for 1988-1992 from the University Medical Center of Eastern North Carolina-Pi
HIV-I infection in a family blood donor [letter]: JPMA J Pak Med Assoc. 1995 Jan;45(1):26. Unique Identifier : AIDSLINE MED/95248588; Mujeeb SA; Kayani N; Khurshid M
Correlates of HIV risk among young adolescents in a large metropolitan midwestern epicenter.: J Sch Health. 1995 Jan;65(1):28-32. Unique Identifier : AIDSLINE MED/95248706; Levy SR; Handler AS; Weeks K; Lampman C; Perhats C; Miller TQ; Flay BR; Prevention Research Center, University of Illinois at Chicago; 60607, USA.; This paper examines levels of participation in and correlates of AIDS-related risk behavior for young adolescents in high-risk communities as determined by proxy indicators such as rates of reported STDs and adolescent pregnancies. Seventh and eighth grade students from two middle schools and ninth grade students from
Tuberculosis today.: Ky Nurse. 1995 Jan-Mar;43(1):18. Unique Identifier : AIDSLINE MED/95248757; Miracle VA
Sources of AIDS information for parents and children.: Med Care. 1995 Apr;33(4):423-31. Unique Identifier : AIDSLINE MED/95248796; Mitchell JM; O'Brien RW; Semansky RM; Iannotti RJ; Graduate Public Policy Program, Georgetown University,; Washington, DC, USA.
[Changes in heroin administration route and frequency of human immunodeficiency virus infection]: Med Clin (Barc). 1995 Feb 25;104(7):249-52. Unique Identifier : AIDSLINE MED/95248800; Torres-Tortosa M; Ruiz Lopez de Tejada MR; Fernandez-Elias M; Perez-Perez C; Fernandez-Conejero E; Ugarte I; Canueto J; Unidad de Enfermedades Infecciosas, Hospital Punta de Europa,; Algeciras, Cadiz.; BACKGROUND: Self-administration of drugs by different intravenous routes may induce a reduction in the organic complications of drug addiction (DA). The aim of this study was to evaluate the changes in the way of drug administration in a series of DA individuals in the province of Cadiz,
Ocular syphilis and neurosyphilis in a patient with human immunodeficiency virus infection.: Md Med J. 1995 Apr;44(4):284-8. Unique Identifier : AIDSLINE MED/95248873; Friedman RF; Ganiban GJ; Liss RA; Friedel SD; Friedenwald Eye Institute, Maryland General Hospital, Baltimore,; USA.; A patient who presented with severely decreased bilateral vision was found to have syphilis and neurosyphilis that responded well to a 14-day course of penicillin and prednisone. The patient tested positive for HIV, which can alter the natural course of syphilis, often making the diagnosis and treatment difficult. Con
HIV/AIDS--an issue in nurse education.: Nurse Educ Today. 1995 Apr;15(2):106-10. Unique Identifier : AIDSLINE MED/95248948; Martin GW; The White Paper, The Health of the Nation (Department of Health 1991), identifies education in HIV/AIDS as an area of priority concern. Statistics have shown that education aimed specifically at gay men has been reduced and that, at the same time, the incidence of infection within this group has risen. There would app
[One antibody preparation is not the other: the role of passive immunotherapy in the treatment of HIV infections (letter)]: Ned Tijdschr Geneeskd. 1995 Apr 22;139(16):850-1. Unique Identifier : AIDSLINE MED/95249030; Laane HM
AIDS: advocacy & activism. What about us?: Nurs Health Care. 1994 Dec;15(10):508-9. Unique Identifier : AIDSLINE MED/95249117; Lederer B
Etiology of cervical cancer: current concepts.: Obstet Gynecol Surv. 1995 Feb;50(2):146-54. Unique Identifier : AIDSLINE MED/95249184; Bornstein J; Rahat MA; Abramovici H; Department of Obstetrics and Gynecology, Carmel Medical Center,; Haifa, Israel.; The data on the etiological factors presented here may enable us to suggest a synergism between the various factors associated with the pathogenesis of cervical cancer. Infection of the cervix by HPV 16/18 may result in persistence of viral DNA. The persistent HPV-DNA undergoes disruption at the E2 region, when integr
Cytotoxicity in human mucosal and cutaneous leishmaniasis.: Parasite Immunol. 1995 Jan;17(1):21-8. Unique Identifier : AIDSLINE MED/95249293; Barral-Netto M; Barral A; Brodskyn C; Carvalho EM; Reed SG; Universidade Federal da Bahia, Salvador-Bahia, Brazil.; CD8+ T cells and lysis of parasitized macrophages seem to be important in the resistance to murine leishmaniasis. In the present study, we evaluated peripheral blood mononuclear cell (PBMC) from patients with either cutaneous (CL) or mucosal (ML) leishmaniasis in cell lysis assays using 51-Cr-labeled Daudi or K562 cel
Cellular responses during liver fluke infection in sheep and its evasion by the parasite.: Parasite Immunol. 1995 Jan;17(1):37-45. Unique Identifier : AIDSLINE MED/95249295; Meeusen E; Lee CS; Rickard MD; Brandon MR; Centre for Animal Biotechnology, University of Melbourne,; Parkville, Victoria, Australia.; The cellular immune response in sheep to an acute and chronic primary and an acute secondary liver fluke infection were examined by immunohistology of liver tissue and flowcytometry of lymphocytes from the draining hepatic lymph nodes. Ten days after primary infection, portal tract areas surrounding migratory tunnels
New Jersey State Nurses Association Position Statement on Minority Health.: N J Nurse. 1995 Jan-Feb;25(1):1, 5. Unique Identifier : AIDSLINE MED/95249344
A-1669: HIV testing of pregnant women [news]: N J Nurse. 1995 Jan-Feb;25(1):12. Unique Identifier : AIDSLINE MED/95249345; Wachter MB
New Jersey State Nurses Association Position Statement on Prenatal HIV Testing.: N J Nurse. 1995 Jan-Feb;25(1):4. Unique Identifier : AIDSLINE MED/95249349
HIV/AIDS and related issues forum: call for speakers.: N J Nurse. 1995 Jan-Feb;25(1):6. Unique Identifier : AIDSLINE MED/95249351; Wurmser T
Plus ca change.: Nurs Times. 1995 Apr 5-11;91(14):54. Unique Identifier : AIDSLINE MED/95249399; Rowden R
HIV specialist is new head at RCN Glasgow [news]: Nurs Times. 1995 Apr 5-11;91(14):9. Unique Identifier : AIDSLINE MED/95249402
A child found to be HIV positive shortly after birth appears now to be clear of the infection [news]: Nurs Times. 1995 Apr 12-18;91(15):11. Unique Identifier : AIDSLINE MED/95249404; Bryson YJ; Pang S; Wi L
Attitude of prison nurse officers to drug misusers.: Nurs Times. 1995 Apr 12-18;91(15):36-7. Unique Identifier : AIDSLINE MED/95249411; Carroll J; The key group involved in delivering health care to drug misusers in prison is the prison nurse officers. The literature suggests that the skills and knowledge base of this professional group has received very little attention. This study looked at the attitudes of prison nurse officers in Scotland towards intravenous
An interview with nursing advisor to govt. of India [interview]: Nurs J India. 1994 May;85(5):98-9. Unique Identifier : AIDSLINE MED/95249438; Kumar TD
Primary lymphomatous effusions in AIDS: a morphological, immunophenotypic, and molecular study.: Mod Pathol. 1995 Jan;8(1):39-45. Unique Identifier : AIDSLINE MED/95249511; Green I; Espiritu E; Ladanyi M; Chaponda R; Wieczorek R; Gallo L; Feiner H; Department of Pathology, New York University Medical Center, New; York, USA.; Lymphomas were documented in pleural effusions or ascites in 18 human immunodeficiency virus-positive (HIV+) patients. Eleven of 12 with clinical data had acquired immunodeficiency syndrome before the diagnosis of lymphoma. In 13 of 15 with data available, a body cavity was the site of initial presentation of lymphoma
Mutagenesis of the putative alpha-helical domain of the Vpr protein of human immunodeficiency virus type 1: effect on stability and virion incorporation.: Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3794-8. Unique Identifier : AIDSLINE MED/95249560; Mahalingam S; Khan SA; Murali R; Jabbar MA; Monken CE; Collman RG; Srinivasan A; Institute of Biotechnology and Advanced Molecular Medicine,; Jefferson Cancer Institute, Thomas Jefferson University,; Philadelphia, PA 19107, USA.; vpr is one of the auxiliary genes of human immunodeficiency virus type 1 (HIV-1) and is conserved in the related HIV-2/simian immunodeficiency virus lentiviruses. The unique feature of Vpr is that it is the only nonstructural protein incorporated into the virus particle. Secondary structural analysis predicted an amph
Differential activation of proliferation and cytotoxicity in human T-cell lymphotropic virus type I Tax-specific CD8 T cells by an altered peptide ligand.: Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):4036-40. Unique Identifier : AIDSLINE MED/95249607; Hollsberg P; Weber WE; Dangond F; Batra V; Sette A; Hafler DA; Laboratory of Molecular Immunology, Brigham & Women's Hospital,; Boston, MA, USA.; Human T-cell leukemia virus type I (HTLV-I) gives rise to a neurologic disease known as HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Although the pathogenesis of the disease is unknown, the presence of a remarkably high frequency of Tax-specific, cytotoxic CD8 T cells may suggest a role of thes
Isolation and molecular characterization of a human T-cell lymphotropic virus type II (HTLV-II), subtype B, from a healthy Pygmy living in a remote area of Cameroon: an ancient origin for HTLV-II in Africa.: Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):4041-5. Unique Identifier : AIDSLINE GENBANK/Z46889; Gessain A; Mauclere P; Froment A; Biglione M; Le Hesran JY; Tekaia F; Millan J; de The G; Unite d'Epidemiologie des Virus Oncogenes, Institut Pasteur,; Paris, France.; We report characterization of a human T-cell lymphotropic virus type II (HTLV-II) isolated from an interleukin 2-dependent CD8 T-cell line derived from peripheral blood mononuclear cells of a healthy, HTLV-II-seropositive female Bakola Pygmy, aged 59, living in a remote equatorial forest area in south
Synthesis and biological activity of pyrimidobenzodiazepine derivatives. New ring systems: triazolo- and tetrazolo-pyrimido-benzodiazepines.: Pharmazie. 1995 Mar;50(3):180-2. Unique Identifier : AIDSLINE MED/95249628; Dlugosz A; Department of Organic Chemistry, Medical University, Faculty of; Pharmacy, Wroclaw, Poland.; New triazolo- and tetrazolo-pyrimidobenzodiazepines were synthesized and screened as anti-HIV, anticancer and immunosuppressive agents. Some of the compounds showed immunosuppressive activity, similar to or stronger than that of cyclosporine A.
AIDS dementia complex.: Plast Surg Nurs. 1994 Fall;14(3):185-6. Unique Identifier : AIDSLINE MED/95249680; Ream-Grace HD
Social support and the development of immune function in human immunodeficiency virus infection.: Psychosom Med. 1995 Jan-Feb;57(1):32-6. Unique Identifier : AIDSLINE MED/95249741; Theorell T; Blomkvist V; Jonsson H; Schulman S; Berntorp E; Stigendal L; National Institute of Psychosocial Factors and Health, Stockholm,; Sweden.; A psychosocial investigation offered to all human immunodeficiency virus (HIV)-infected men with moderately severe or severe hemophilia in Sweden was made in 1986. Most of these men had been infected in the years 1980 to 1984 and told about their infections in 1985. Forty-nine subj
[Diarrhea and fecal expulsion of whitish structure in a patient with acquired immunodeficiency syndrome]: Rev Clin Esp. 1995 Feb;195(2):117, 123. Unique Identifier : AIDSLINE MED/95249769; Prada JL; Torre-Cisneros J; Villanueva JL; Kindelan JM; Jurado R; Sanchez-Guijo P; Unidad de Enfermedades Infecciosas, Hospital Universitario Reina; Sofia, Cordoba.
[Large T-cell (Ki-1) anaplastic lymphoma in a patient with human immunodeficiency virus infection, an exceptional association (letter)]: Rev Clin Esp. 1995 Feb;195(2):126-7. Unique Identifier : AIDSLINE MED/95249771; Escobedo Palau JA; Rubio Felix SA; Gracia Nasarre M; Marigil Gomez MA
[Idiopathic T CD4+ lymphocytopenia and opportunistic infection without human immunodeficiency virus infection (letter)]: Rev Clin Esp. 1995 Feb;195(2):127-8. Unique Identifier : AIDSLINE MED/95249772; Sanchez Roman J; Castillo Palmo MJ; Rey Romero C; Mendoza Muro MD
[Evaluation of serum adenosine deaminase as a prognostic marker in the treatment of human immunodeficiency virus infection with zidovudine]: Rev Clin Esp. 1995 Feb;195(2):74-7. Unique Identifier : AIDSLINE MED/95249777; Carrera J; Porras JA; Vidal F; Pinto B; Richart C; Servicio de Analisis Clinicos, Hospital Universitari de; Tarragona Joan XXIII, Universidad Rovira i Virgili, Tarragona.; BACKGROUND. Adenosine deaminase (ADA) is a key enzyme in cellular immunity. It catalyses the reaction 2 deoxyadenosine to 2 deoxiinosine, a critical step in the production of essential metabolites for the synthesis of nucleic acids. Its main physiological activity occurs in T cells of lymphoid tissue. The advanced HIV
[Thrombocytopenia associated with human immunodeficiency virus infection. Pathogenic significance of platelet autoimmunity phenomena]: Rev Clin Esp. 1995 Feb;195(2):78-82. Unique Identifier : AIDSLINE MED/95249778; Carton Sanchez JA; Llorente de Jesus MR; Rodriguez Vicente P; Servicios de Medicina Interna (Infecciones) y Hematologia,; Hospital Central de Asturias (Nuestra Senora de Covadonga,; Oviedo.; OBJECTIVES. Several mechanisms in formation and destruction of platelets could be involved in thrombocytopenia associated with HIV infection (TP/HIV). This epidemiological study investigated the pathogenic role of immunoglobulins associated with platelets (IAP), circulant immunocomplexes (CIC) and anticardiolipin anti
[Liver tuberculous abscess in patients with human immunodeficiency virus infection: report of 2 cases and review of the literature]: Rev Clin Esp. 1995 Feb;195(2):89-91. Unique Identifier : AIDSLINE MED/95249780; Roig Rico P; Perez Rodriguez L; Navarro Ibanez V; Lopez Perezagua MM; Portilla Sogorb J; Cuadrado Pastor JM; Servicio de Medicina Interna, Hospital del SVS San Juan de; Alicante.; Two cases are reported of hepatic tuberculous abscesses (HTBA) in patients infected with the human immunodeficiency virus (HIV), stressing the rarity of this location. Likewise, a review is made of cases reported in the literature. Our two patients presented with a prolonged febrile condition, with constitutional symp
[Eosinophilic pustular folliculitis in acquired immunodeficiency syndrome. Report of 6 cases]: Rev Clin Esp. 1995 Feb;195(2):92-6. Unique Identifier : AIDSLINE MED/95249781; Ferrer S; Baselga E; Domingo P; Puig M; Ris J; Barrio JL; Nolla J; Servicios de Medicina Interna y Dermatologia, Hospital de la; Santa Creu i Sant Pau, Universitat Autonoma de Barcelona.; Eosinophilic pustulous foliculitis (EPF) is a rare dermatosis which has been reported in association with the human immunodeficiency virus infection. Six patients infected with HIV are reported with advanced disease in whom the diagnosis of EPF was made. All patients has a highly pruritic follicular papular rash. In a
[Microsporidiosis in patients with AIDS and chronic diarrhea (letter)]: Rev Med Chil. 1994 Jul;122(7):834-5. Unique Identifier : AIDSLINE MED/95249826; Weitz Vattuone JC; Bryan R
[Visceral leishmaniasis and acquired immunodeficiency syndrome (AIDS). Report of a case]: Rev Inst Med Trop Sao Paulo. 1994 Jul-Aug;36(4):385-7. Unique Identifier : AIDSLINE MED/95249860; Viana GM; Lewi DS; Olzon P; Freire CM; Morelli VM; Vas LH; Felizardo M; Disciplina de Doencas Infecciosas e Parasitarias, Escola; Paulista de Medicina, Sao Paulo, Brasil.; This is a case report that describe an association of AIDS, visceral leishmaniasis and probable disseminated tuberculosis. Due to the spread of AIDS in developing areas worldwide this association would be more frequently, seen on subjects from endemic areas where this protozoonosis is prevalent. More than one opportun
[Cerebral toxoplasmosis with central diabetes insipidus and panhypopituitarism in a patient with AIDS]: Schweiz Med Wochenschr. 1995 Apr 8;125(14):684-7. Unique Identifier : AIDSLINE MED/95249946; Brandle M; Vernazza PL; Oesterle M; Galeazzi RL; Medizinische Klinik A, Kantonsspital St. Gallen.; Endocrine disorders in the course of HIV infection are often a result of opportunistic infections of endocrine organs. We describe the case of a 30-year-old HIV positive man in whom diabetes insipidus developed initially with no abnormal findings in cranial magnetic resonance imaging. 2 months later the patient presen
[Concerning: K. Boggian, H.J. Leu, J Schneider, M. Turina, D, Oertle: True aneurysm of the ascending aorta in HIV disease (Schweiz Med Wochenschr 1994; 124: 2083-2087 (letter)]: Schweiz Med Wochenschr. 1995 Apr 8;125(14):706-7. Unique Identifier : AIDSLINE MED/95249948; Carrel T
FDA puts the brakes on xenotransplants [news] [published erratum appears in Science 1995 May 19;268(5213):961]: Science. 1995 May 5;268(5211):630-1. Unique Identifier : AIDSLINE MED/95249965; Nowak R
Perceptions of social support and psychological adaptation to sexually acquired HIV among white and African American men.: Soc Work. 1995 Mar;40(2):215-24. Unique Identifier : AIDSLINE MED/95250030; Grant LM; Ostrow DG; School of Social Work, University of Michigan, Ann Arbor 48109.; Although the research literature documents the impact of social support on the mental health of people with human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS), the assumption that relationships between social support and mental health functioning are comparable across ethnically distinct
Primary small bowel lymphoma manifested as obstructive jaundice in a patient with AIDS.: South Med J. 1995 May;88(5):583-5. Unique Identifier : AIDSLINE MED/95250056; Schoeppner HL; Wong DK; Bresalier RS; Department of Internal Medicine, Henry Ford Hospital, Detroit, MI; 48202, USA.; We describe a patient with acquired immunodeficiency syndrome (AIDS) and non-Hodgkin s lymphoma of the duodenum manifested as obstructive jaundice. Endoscopic retrograde cholangiography led to the diagnosis and was used to relieve the obstruction. The patient received chemotherapy
Pneumonia due to Staphylococcus aureus in a patient with AIDS: review of incidence and report of an atypical roentgenographic presentation.: South Med J. 1995 May;88(5):586-90. Unique Identifier : AIDSLINE MED/95250057; Dicpinigaitis PV; Levy DE; Gnass RD; Bernstein RG; Department of Medicine, Albert Einstein College of Medicine,; Bronx, NY, USA.; Multiple defects in host defense mechanisms produce an increased incidence of community-acquired bacterial pneumonia in individuals infected with the human immunodeficiency virus. Clinical studies suggest that Staphylococcus aureus is an uncommon cause of such infections, though its incidence is increased in the setti
Sarcoid myopathy in a patient with human immunodeficiency virus infection.: South Med J. 1995 May;88(5):591-5. Unique Identifier : AIDSLINE MED/95250058; Granieri J; Wisnieski JJ; Graham RC; Smith H; Gogate P; Aucott JN; Cleveland Veterans Affairs Medical Center, OH 44106, USA.; Although neither sarcoidosis nor HIV infection is rare, only eight patients with both diseases have been described. None of the eight had sarcoid myopathy. We describe a patient who had HIV infection and decreased CD4+ T-lymphocytes as well as sarcoidosis with muscle involvement. During 3 years of observation, primary
In vivo depletion of CD8+ T cells results in Th2 cytokine production and alternate mechanisms of allograft rejection.: Transplantation. 1995 Apr 27;59(8):1155-61. Unique Identifier : AIDSLINE MED/95250170; Chan SY; DeBruyne LA; Goodman RE; Eichwald EJ; Bishop DK; Department of Surgery, University of Michigan School of Medicine,; Ann Arbor 48109, USA.; A current hypothesis states that Th1 cytokines promote allograft rejection and that Th2 cytokines promote graft acceptance. We present data that question the tolerogenic activity of Th2 cytokines, and we suggest that Th2 cytokines may evoke allograft rejection by recruitment of alternate effector mechanisms. Unmodifie
Tolerance induced by direct inoculation of donor antigen into the thymus in low and high responder rodents.: Transplantation. 1995 Apr 27;59(8):1171-6. Unique Identifier : AIDSLINE MED/95250172; Alfrey EJ; Wang X; Lee L; Holm B; Kim J; Adams G; Dafoe DC; Department of Surgery, School of Medicine, Stanford University,; California 94305, USA.; A novel approach to tolerance induction in rats was recently described where donor antigen is inoculated directly into the thymus along with a brief period of immunosuppression in a pretransplant strategy. To develop a strategy that has more clinical appeal, we evaluated the timing of donor antigen inoculation in rela
Effector cells must recognize antigens expressed in the graft to cause efficient skin graft rejection in SCID mice.: Transplantation. 1995 Apr 27;59(8):1223-7. Unique Identifier : AIDSLINE MED/95250184; Wecker H; Grusby MJ; Auchincloss H Jr; Transplantation Unit, Harvard Medical School, Massachusetts; General Hospital, Boston 02114, USA.
Gene-targeted inhibition of transactivation of human immunodeficiency virus type-1 (HIV-1)-LTR by antisense oligonucleotides.: Virus Genes. 1995 Jan;9(2):113-9. Unique Identifier : AIDSLINE MED/95250303; Demirhan I; Hasselmayer O; Hofmann D; Chandra A; Svinarchuk FP; Vlassov VV; Engels J; Chandra P; Laboratory of Molecular Biology, Frankfurt University School of; Medicine, FRG.; We have used an in vitro approach to study the efficiency of antisense oligonucleotides in inhibiting LTR-(HIV-1)-directed CAT expression catalyzed by tat protein, the functional protein of the transactivator gene. We selected the target sequence localized near the 5 end of the tat mRNA. The following conclusions can
An analysis of the role of skin Langerhans cells (LC) in the cytoplasmic processing of HIV-1 peptides after peplotion transepidermal transfer and HLA class I presentation to CD8+ CTLs--an approach to immunization of humans.: Virus Genes. 1995 Jan;9(2):133-47. Unique Identifier : AIDSLINE MED/95250305; Becker Y; Department of Molecular Virology, Faculty of Medicine, Hebrew; University of Jerusalem, Israel.; Skin Langerhans cells (LC) are antigen-presenting cells capable of expressing MHC class I and class II molecules on the plasma membrane. This molecular activity was reviewed to combine the knowledge of peptide presentation by MHC and HLA class I and class II molecules to prime CD8+ cytotoxic T cells (CTLs) and CD4+ T
Augmentation of c-fos and c-jun expression in transgenic mice carrying the human T-cell leukemia virus type-I tax gene.: Virus Genes. 1995 Jan;9(2):161-70. Unique Identifier : AIDSLINE MED/95250308; Iwakura Y; Tosu M; Yoshida E; Saijo S; Nakayama-Yamada J; Itagaki K; Asano M; Siomi H; Hatanaka M; Takeda T; et al; Institute of Medical Science, University of Tokyo, Japan.; To analyze the effect of human T-cell leukemia virus type I (HTLV-I) on cellular gene expression and its relation to tumorigenesis, two lines of transgenic mice carrying the long terminal repeat (LTR)-env-pX-LTR regions of the HTLV-I genome were produced. The transgene was expressed in many organs, including the brain
Correlates of stress in HIV disease.: West J Nurs Res. 1995 Apr;17(2):141-55. Unique Identifier : AIDSLINE MED/95250329; McCain NL; Cella DF; Department of Medical Nursing, Rush University, Chicago, IL, USA.; A group of 53 men with HIV disease participated in this correlational study of the relationships among psychological distress, quality of life, uncertainty, coping patterns, stress, and CD4+ T-lymphocyte levels. Meaningful correlations (r > .40, p
[Child health in our world]: Z Ernahrungswiss. 1994 Dec;33(4):248-57. Unique Identifier : AIDSLINE MED/95250350; Krawinkel MB; Kinderklinik, Universitat Kiel.; The health of children in poor countries is determined by their nutritional status and by the economic conditions of their families and societies. Socioeconomic differences are correlated with the infant mortality rate (IMR). The decline of the IMR in the industrialized countries mainly occurred before 1960. Programs
Influence of anti-inflammatory drugs on adhesion of neutrophils to endothelial cells cultured on microcarriers: a novel in vitro system as an alternative to animal experimentation.: Zentralbl Veterinarmed A. 1994 Nov;41(9):671-82. Unique Identifier : AIDSLINE MED/95250393; Zwahlen RD; Holden WJ; Wyder-Walther M; Holub M; Moiola F; Institute of Veterinary Pathology, University of Bern,; Switzerland.; Pharmacological control of inflammation by steroidal (SAIDs) and nonsteroidal (NSAIDs) antiinflammatory drugs is of substantial clinical importance. To reduce the number of animals used in pharmacological and toxicological evaluation of these drugs we developed a novel assay to determine adhesion of bovine neutrophils
Interferon-gamma, interleukin-4 and transforming growth factor-beta mRNA expression in multiple sclerosis and myasthenia gravis.: Acta Neurol Scand Suppl. 1994;158:1-58. Unique Identifier : AIDSLINE MED/95250431; Link J; Department of Clinical Neuroscience and Family Medicine,; Karolinska Institute, Stockholm, Sweden.; BACKGROUND. Multiple sclerosis (MS) is characterized by perivascular inflammation and high levels of circulating T and B lymphocytes that respond to the myelin antigens myelin basic protein (MBP) and proteolipid protein (PLP), thereby suggesting a role for immunoregulatory cytokines. MATERIALS AND METHOD. Blood mononu
Heightened sensitivity of the esophagus to radiation in a patient with AIDS.: Am J Gastroenterol. 1995 May;90(5):812-4. Unique Identifier : AIDSLINE MED/95250765; Costleigh BJ; Miyamoto CT; Micaily B; Brady LW; Department of Radiation Oncology and Nuclear Medicine, Hahnemann; University Hospital, Philadelphia, Pennsylvania, USA.; Esophageal stricture is an uncommon complication in HIV-negative patients treated with radiation to the chest for lung cancer. There have been a number of recent reports on the association of cancer and HIV-positive patients, as well as a greater sensitivity to radiation therapy of the mucous membranes in HIV/AIDS pat
Long-term observation of 208 adults with chronic idiopathic thrombocytopenic purpura.: Am J Med. 1995 May;98(5):436-42. Unique Identifier : AIDSLINE MED/95250795; Stasi R; Stipa E; Masi M; Cecconi M; Scimo MT; Oliva F; Sciarra A; Perrotti AP; Adomo G; Amadori S; et al; Department of Hematology, University of Rome Tor Vergata, S.; Eugenio Hospital, Italy.; PURPOSE: To define response to therapy and ultimate outcome of adults with idiopathic thrombocytopenic purpura (ITP). PATIENTS AND METHODS: We retrospectively analyzed patients with ITP diagnosed between 1978 and 1988, and reexamined them between June 1992 and March 1993. Data from 208 cases were collected. Median pat
Hypocholesterolemia and human immunodeficiency virus-1 (HIV-1) infection [letter; comment]: Am J Med. 1995 May;98(5):518. Unique Identifier : AIDSLINE MED/95250812; Dursun SM; Reveley MA
Hypocholesterolemia and human immunodeficiency virus-1 (HIV-1) infection [letter; comment]: Am J Med. 1995 May;98(5):518-9; discussion 519-20. Unique Identifier : AIDSLINE MED/95250813; Constans J; Pellegrin JL; Peuchant E; Dumon MF; Sergeant C; Simonoff M; Brossard G; Barbeau P; Clerc M; Leng B; et al
Case report: fulminant Kaposi's sarcoma after orthotopic liver transplantation.: Am J Med Sci. 1995 May;309(5):278-81. Unique Identifier : AIDSLINE MED/95250818; Hertzler G; Gordon SM; Piratzky J; Henderson JM; Gal AA; Department of Pathology and Laboratory Medicine, Emory University; School of Medicine, Atlanta, Georgia, USA.; Fulminant multicentric Kaposi s sarcoma developed in an American-born HIV-negative patient 8 months after orthotopic liver transplantation. Despite its rarity in liver transplantation, Kaposi s sarcoma should be considered in the differential diagnosis in hepatic allograft recipients presenting with rapidly growing cu
Dose-related difference in progression rates of cytomegalovirus retinopathy during foscarnet maintenance therapy. AIDS Clinical Trials Group Protocol 915 Team.: Am J Ophthalmol. 1995 May;119(5):576-86. Unique Identifier : AIDSLINE MED/95250862; Holland GN; Levinson RD; Jacobson MA; UCLA Ocular Inflammatory Disease Center, Jules Stein Eye; Institute 90024-7003, USA.; PURPOSE: A previous dose-ranging study of foscarnet maintenance therapy for cytomegalovirus retinopathy showed a positive relationship between dose and survival but could not confirm a relationship between dose and time to first progression. This retrospective analysis of data from
Viral sensitivity testing in patients with cytomegalovirus retinitis clinically resistant to foscarnet or ganciclovir.: Am J Ophthalmol. 1995 May;119(5):587-96. Unique Identifier : AIDSLINE MED/95250863; Dunn JP; MacCumber MW; Forman MS; Charache P; Apuzzo L; Jabs DA; Wilmer Ophthalmological Institute, Baltimore, MD 21205, USA.; PURPOSE: Resistance to antiviral therapy is a potential cause of progression of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. We investigated the results of viral sensitivity testing in a series of patients with clinically resistant retinitis wh
Female condom use among injection drug- and crack cocaine-using women [letter]: Am J Public Health. 1995 May;85(5):736-7. Unique Identifier : AIDSLINE MED/95251146; Ashery RS; Carlson RG; Falck RS; Siegal HA; Wang J
Politics and public health research: HIV prevention policy in the schools [letter; comment]: Am J Public Health. 1995 May;85(5):738. Unique Identifier : AIDSLINE MED/95251148; Melese-d'Hospital I; Colman SS
Is gender dysphoria dysphoric? Elevated depression and anxiety in gender dysphoric and nondysphoric homosexual and bisexual men in an HIV sample. HNRC Group.: Arch Sex Behav. 1995 Feb;24(1):55-72. Unique Identifier : AIDSLINE MED/95251530; Weinrich JD; Atkinson JH Jr; McCutchan JA; Grant I; Few if any studies before the AIDS epidemic suggested that male homosexuals may on average have higher levels of depression than male heterosexuals. However, several samples of homosexual and bisexual men in HIV studies suggest that depression and anxiety are high in these populations, and that this psychiatric morbid
Neuropsychologic impairment in early HIV infection. A risk factor for work disability.: Arch Neurol. 1995 May;52(5):525-30. Unique Identifier : AIDSLINE MED/95251575; Albert SM; Marder K; Dooneief G; Bell K; Sano M; Todak G; Stern Y; Gertrude H. Sergievsky Center, College of Physicians and; Surgeons, Columbia University, New York, USA.; OBJECTIVE: To explore the functional significance of incident neuropsychologic impairment among initially asymptomatic subjects infected with human immunodeficiency virus. DESIGN: Prospective, observational cohort study of homosexual and bisexual men to examine the incidence of work disability related to the onset of
Expression of kappa opioid receptors in human and monkey lymphocytes.: Biochem Biophys Res Commun. 1995 Apr 26;209(3):1003-10. Unique Identifier : AIDSLINE MED/95251683; Chuang LF; Chuang TK; Killam KF Jr; Qiu Q; Wang XR; Lin JJ; Kung HF; Sheng W; Chao C; Yu L; et al; Department of Medical Pharmacology and Toxicology, University of; California, Davis 95616, USA.; mRNA encoding the kappa opioid receptor gene sequence was identified and isolated from various human lymphocytic cells: CEM x174 (a hybrid of T and B origin) cells, Jurkat-T4 cells, human peripheral blood mononuclear cells (PBMC) and purified CD4+ cells. Analyzing the cDNA sequences of RNA transcripts spanning the put
Role of humoral factors in the progression of HIV disease.: Immunol Today. 1995 Apr;16(4):167-9. Unique Identifier : AIDSLINE MED/95251757; Fust G; Dierich MP; Hidvegi T; National Institute of Haematology, Blood Transfusion and; Immunology, Budapest, Hungary.
Immune activation is a dominant factor in the pathogenesis of African AIDS.: Immunol Today. 1995 Apr;16(4):187-91. Unique Identifier : AIDSLINE MED/95251762; Bentwich Z; Kalinkovich A; Weisman Z; R. Ben-Ari Institute of Clinical Immunology, Kaplan Hospital,; Hebrew University Hadassah Medical School, Rehovot, Israel.; The AIDS epidemic in Africa is very different from the epidemic in the West. As suggested here by Zvi Bentwich, Alexander Kalinkovich and Ziva Weisman, this appears to be primarily a consequence of the over-activation of the immune system in the African population, owing to the extremely high prevalence of infections,
Ultrastructural identification of Ricinus communis agglutinin-1 positive cells in primary dissociated cell cultures of human embryonic brain.: Arch Histol Cytol. 1994 Dec;57(5):481-91. Unique Identifier : AIDSLINE MED/95251915; Bobryshev Y; Ashwell K; Institute of the Human Brain, St Petersburg, Russia.; While Ricinus communis agglutinin 1 (RCA-1) can be used as a specific marker to study the development and differentiation of microglial cells in human embryogenesis, little is known about the structural heterogeneity and nature of RCA-1+ cells. To analyse the structural peculiarities of RCA-1+ cells, we have used prim
Update on long-term symptomless HIV type 1 infection in recipients of blood products from a single donor [letter]: AIDS Res Hum Retroviruses. 1995 Jan;11(1):1. Unique Identifier : AIDSLINE MED/95251921; Learmont J; Cook L; Dunckley H; Sullivan JS
Limited sequence diversity of the HIV type 1 protease gene from clinical isolates and in vitro susceptibility to HIV protease inhibitors.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):107-13. Unique Identifier : AIDSLINE MED/95251922; Winslow DL; Stack S; King R; Scarnati H; Bincsik A; Otto MJ; Du Pont-Merck Pharmaceutical Company, Glenolden, Pennsylvania,; USA.; Proviral DNAs from 3 laboratory strains and 21 clinical isolates of HIV-1 were extracted from infected cells after proteinase K digestion and the protease gene was PCR amplified and sequenced directly by the Sanger method. In vitro susceptibilities of the virus isolates to
HIV-1 infection of the thymus: evidence for a cytopathic and thymotropic viral variant in vivo.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):11-9. Unique Identifier : AIDSLINE MED/95251923; Calabro ML; Zanotto C; Calderazzo F; Crivellaro C; Del Mistro A; De Rossi A; Chieco-Bianchi L; Institute of Oncology, University of Padua, Italy.; As thymocyte infection may represent one of the mechanisms responsible for CD4+ T lymphocyte depletion in HIV-1-infected individuals, we studied the occurrence of HIV-1 infection in the thymus in vivo. Thymus (THYPD) and peripheral blood (PBLPD) primary viral isolates were obtained from an HIV-1-infected patient; rest
Inhibition of human immunodeficiency virus type 1 integrase by a hydrophobic cation: the phenanthroline-cuprous complex.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):115-25. Unique Identifier : AIDSLINE MED/95251924; Mazumder A; Gupta M; Perrin DM; Sigman DS; Rabinovitz M; Pommier Y; Laboratory of Molecular Pharmacology, National Cancer Institute,; Bethesda, Maryland 20892-4255, USA.; The human immunodeficiency virus type 1 integrase (HIV-1 integrase) is required for integration of a double-stranded DNA copy of the viral RNA genome into a host chromosome and for HIV replication. We have examined the effects of 2:1 1,10-phenanthroline-cuprous complexes on purified HIV-1 integrase. Although the uncom
Bathophenanthroline disulfonate and soluble CD4 as probes for early events of HIV type 1 entry.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):127-39. Unique Identifier : AIDSLINE MED/95251925; Demaria S; Tilley SA; Pinter A; Bushkin Y; Public Health Research Institute, New York, New York 10016, USA.; We report here that a metalloprotease inhibitor, bathophenanthroline disulfonate (Bphe-ds), neutralizes both laboratory-adapted and primary strains of HIV-1. Presaturation of Bphe-ds with zinc does not alter its neutralizing activity, suggesting that the metal-chelating ability of Bphe-ds is not required for neutraliz
Supplementation of N-acetylcysteine fails to increase glutathione in lymphocytes and plasma of patients with AIDS.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):141-3. Unique Identifier : AIDSLINE MED/95251926; Witschi A; Junker E; Schranz C; Speck RF; Lauterburg BH; Department of Clinical Pharmacology, University of Bern,; Switzerland.; Because glutathione (GSH) in plasma and lymphocytes of HIV-infected patients is low, adjunct therapy with N-acetylcysteine (NAC) to restore GSH homeostasis has been proposed. To investigate the effect of NAC on the GSH status we treated six patients with AIDS with 1.8 g/day of NAC for 2 weeks. During treatment the pla
Cell surface phenotypic changes induced in H9 T cells chronically infected with HTLV type I or HIV type 1 or coinfected with the two viruses.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):145-54. Unique Identifier : AIDSLINE MED/95251927; Noraz N; Verrier B; Fraisier C; Desgranges C; INSERM U271, Lyon, France.; To investigate whether HTLV-I infection, HIV-I infection, or HIV-I infection of HTLV-I-infected cells affect the expression of cellular surface molecules, an HTLV-I-infected T cell line derived from the H9 T cell line was established (H36). H9 cells uninfected or infected with HTLV-I were then infected with HIV-1. We
Markers of foamy virus infections in monkeys, apes, and accidentally infected humans: appropriate testing fails to confirm suspected foamy virus prevalence in humans.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):161-70. Unique Identifier : AIDSLINE MED/95251929; Schweizer M; Turek R; Hahn H; Schliephake A; Netzer KO; Eder G; Reinhardt M; Rethwilm A; Neumann-Haefelin D; Abteilung Virologie, University of Freiburg, Germany.; Foamy viruses (FVs) persist in healthy individuals of various mammalian species, including nonhuman primates. Laboratory markers of FV infection are (1) virus in throat epithelium or peripheral blood lymphocytes (PBLs), (2) proviral DNA sequences in PBLs and various solid organs, and (3) antibodies reactive to viral a
Vertical transmission of feline immunodeficiency virus.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):171-82. Unique Identifier : AIDSLINE MED/95251930; O'Neil LL; Burkhard MJ; Diehl LJ; Hoover EA; Department of Pathology, Colorado State University, Fort Collins; 80523, USA.; We studied vertical transmission of feline immunodeficiency virus (FIV) to determine whether it might provide a model with which to study intervention strategies for mother-to-offspring transmission of human immunodeficiency virus (HIV). We found that pregnant cats acutely infected with FIV (FIV-CSU-2771) transmitted
New crown motif of an HIV-1 V3 loop sequence from a Ugandan AIDS patient.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):183-4. Unique Identifier : AIDSLINE GENBANK/U15007; von Brunn A; von Brunn B; Eberle J; Biryahwaho B; Downing RG; Gurtler L; Max-von-Pettenkofer-Institut, Munchen, Germany.
Uncommon gp120 cysteine residues found in primary HIV-1 isolates.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):185-8. Unique Identifier : AIDSLINE GENBANK/U16335; Wang WK; Essex M; Lee TH; Department of Cancer Biology, Harvard School of Public Health,; Boston, MA 02115, USA.
Sequential determination of viral load and phenotype in human immunodeficiency virus type 1 infection.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):3-9. Unique Identifier : AIDSLINE MED/95251934; Daar ES; Chernyavskiy T; Zhao JQ; Krogstad P; Chen IS; Zack JA; Division of Infectious Diseases, Cedars-Sinai Medical Center,; UCLA School of Medicine 90048, USA.; Detailed studies of HIV viral load and phenotype were performed on sequentially cryopreserved peripheral blood mononuclear cells (PBMCs) from eight infected individuals followed in the Los Angeles Multicenter AIDS Cohort Study. Three individuals remained clinically and immunologically stable over a 5- to 8-year period
Constitutive expression of human immunodeficiency virus type 1 tat gene inhibits interleukin 2 and interleukin 2 receptor expression in a human CD4+ T lymphoid (H9) cell line.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):31-40. Unique Identifier : AIDSLINE MED/95251935; Puri RK; Leland P; Aggarwal BB; Laboratory of Molecular Tumor Biology, FDA, Bethesda, Maryland; 20892, USA.; Human immunodeficiency virus (HIV-1) tat, a trans-activator of the HIV long terminal repeat, is essential for HIV replication and causes inhibition of antigen-mediated T cell proliferation. To understand the mechanism of inhibition of T cell proliferation, we have investigated the regulation of
X irradiation-induced transcription from the HIV type 1 long terminal repeat.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):41-3. Unique Identifier : AIDSLINE MED/95251936; Faure E; Cavard C; Zider A; Guillet JP; Resbeut M; Champion S; Institut de Chimie Biologique, Universite de Provence,; Marseille, France.; It has been previously shown in vitro and in vivo that the human immunodeficiency virus type 1 can be dramatically enhanced by certain heterologous viral, chemical, and physical (ultraviolet irradiation) agents. A common denominator shared by these agents is their ability to cause stress responses in cells. To analyze
Superinfection of a defective human immunodeficiency virus type 1 provirus-carrying T cell clone with vif or vpu mutants gives cytopathic virus particles by homologous recombination.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):45-53. Unique Identifier : AIDSLINE MED/95251937; Kishi M; Tokunaga K; Zheng YH; Bahmani MK; Kakinuma M; Nonoyama M; Lai PK; Ikuta K; Section of Serology, Hokkaido University, Sapporo, Japan.; The partially CD4-expressing T cell clone, Vpr-1, which carries a latent vpr-defective HIV-1 genome and expresses HIV-1 Nef protein only, was permissive to superinfection by HIV-1. Superinfection of Vpr-1 with vif- or vpu-defective mutants, which were noncytopathic, reactivated the vpr-defective virus and led to homol
Ultrastructural evidence of an interaction between Env and Gag proteins during assembly of HIV type 1.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):55-64. Unique Identifier : AIDSLINE MED/95251938; Bugelski PJ; Maleeff BE; Klinkner AM; Ventre J; Hart TK; Department of Toxicology, SmithKline Beecham Pharmaceuticals,; Philadelphia, Pennsylvania, USA.; Assembly and budding of retroviruses is believed to involve a complex interaction of envelope and capsid proteins at the host cell membrane. The nature of these interactions is, however, incompletely understood. Studies of the topography of the surface of HIV-1 have shown that the envelope glycoprotein projections (kn
Oligomerization of the HIV type 2 Nef protein: mutational analysis of the heptad leucine repeat motif and cysteine residues.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):65-79. Unique Identifier : AIDSLINE MED/95251939; Hodge DR; Chen YM; Samuel KP; Laboratory of Molecular Oncology, National Cancer Institute,; Frederick Research and Development Center, Maryland 21702, USA.; The human immunodeficiency virus type 2 (HIV-2) Nef protein expressed in Escherichia coli forms highly stable homooligomeric complexes in vitro. Similarly, the native protein synthesized in the persistently infected H9 T cell line also forms stable homooligomers in vivo. To determine whether homooligomer formation is
Enhanced proteolytic processing of the human immunodeficiency virus type 1 envelope protein in murine Ltk(-) cells.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):81-5. Unique Identifier : AIDSLINE MED/95251940; Rodriguez D; Rodriguez JR; Esteban M; Centro Nacional de Biotecnologia, CSIC, Campus Universidad; Autonoma, Madrid, Spain.; Proteolytic processing of the human immunodeficiency virus type 1 (HIV-1) envelope (Env) precursor glycoprotein (gp160) to produce the mature gp120 and gp41 proteins is required for virus infection and virus-induced cell fusion. It has also been suggested that cleavage of gp120 at the immunodominant V3 loop region is
Lectin-mediated effects on HIV type 1 infection in vitro.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):87-95. Unique Identifier : AIDSLINE MED/95251941; Hammar L; Hirsch I; Machado AA; De Mareuil J; Baillon JG; Bolmont C; Chermann JC; Department of Dermatology, Karolinska Institute, Stockholm,; Sweden.; Lectins with specificity for terminal mannose residues and anti-mannan antibodies neutralize HIV-1 infection in vitro. This is assumed to be caused by binding of the agents to the viral glycoproteins. In this study we show that one such agent, the Galanthus nivalis lectin (GNA), also blocks infection at the target cel
Activation of interleukin 4- and interleukin 6-secreting cells by HIV-specific synthetic peptides.: AIDS Res Hum Retroviruses. 1995 Jan;11(1):97-105. Unique Identifier : AIDSLINE MED/95251942; Klinman DM; Haynes BF; Conover J; Section of Retroviral Immunology, Food and Drug Administration,; Bethesda, Maryland 20892, USA.; Peptides were synthesized in which the type-specific determinant of the V3 loop region of gp120 (SP10) was expressed C terminal to a conserved T helper epitope (T1) on the same molecule. These T1-SP10 peptides can stimulate both cell-mediated and humoral immune responses. The current work used a novel approach to stud
The first report of familial adult T-cell leukaemia lymphoma in the United Kingdom.: Br J Haematol. 1995 Mar;89(3):615-9. Unique Identifier : AIDSLINE MED/95252127; Matutes E; Spittle MF; Smith NP; Eady RA; Catovsky D; Academic Department of Haematology and Cytogenetics, Royal; Marsden Hospital, London.; We describe two siblings who developed adult T-cell leukaemia lymphoma (ATLL) within 4 years. Both were black of Afro-Caribbean extraction, but one had been born in the United Kingdom and had visited the Caribbean only once. Both patients were HTLV-1 seropositive, as was their mother;
Identification of biclonal (duplex) leukaemic cells expressing either CD4+/CD8- or CD4-/CD8+ from a patient with adult T-cell leukaemia/lymphoma.: Br J Haematol. 1995 Mar;89(3):669-71. Unique Identifier : AIDSLINE MED/95252143; Kondo S; Kotani T; Tsumori S; Narahara S; Aratake Y; Kobayashi M; Takahashi M; Inoue S; Ohtaki S; Blood Transfusion Division, Miyazaki Medical College, Japan.; A 24-year-old Japanese woman was admitted to our hospital in 1987 with a chief complaint of skin eruptions, and was diagnosed as having chronic ATLL. In 1993 the leucocyte count increased gradually to 126.0 x 10(9)/l with 91.5% abnormal lymphocytes expressing two different types of antigenicity, either CD+/CD8- or CD4
Transmission of human T-lymphotrophic virus type 1 by bone marrow transplantation [letter; comment]: Br J Haematol. 1995 Mar;89(3):690-1. Unique Identifier : AIDSLINE MED/95252155; Miyoshi I; Murata N; Machida H; Taguchi H
Competition of HLA-DR and a beta 2 domain peptide for HIV envelope glycoprotein gp120 binding to CD4.: Int Immunol. 1995 Feb;7(2):191-7. Unique Identifier : AIDSLINE MED/95252186; Autiero M; Houlgatte R; Martin M; Auffray C; Guardiola J; Piatier-Tonneau D; International Institute of Genetics and Biophysics, Naples,; Italy.; HLA class II molecules and the HIV envelope glycoprotein gp120 are ligands of CD4. Reciprocal interaction sites have been well characterized for gp120 and CD4, but require further definition for HLA class II and CD4. A major CD4 binding site encompassing amino acids 134-148 in the beta 2 domain of HLA-DR has been prev
Inhibition of HIV-1 by modification of a host membrane protease.: Int Immunol. 1995 Feb;7(2):239-49. Unique Identifier : AIDSLINE MED/95252192; Bristow CL; Fiscus SA; Flood PM; Arnold RR; Department of Periodontics, School of Dentistry, University of; North Carolina-Chapel Hill 27599-7455, USA.; While it is clear that CD4 is the receptor for the gp120 envelope protein of HIV-1, substantial evidence suggests that other host cell proteins are required for successful membrane fusion. Studies were initiated to examine the potential for a protein receptor which has an elastase-like character to participate in fusi
Psychiatric disorders of opioid addicts entering treatment: preliminary data.: J Addict Dis. 1994;13(3):1-11. Unique Identifier : AIDSLINE MED/95252230; Abbott PJ; Weller SB; Walker SR; Treatment Division, University of New Mexico, School of Medicine,; Albuquerque 87106, USA.; Psychiatric disorders have become an increasing concern in the treatment of substance abusers. The introduction of the Human Immunodeficiency Virus (HIV) into this population has further complicated treatment. This study examines the prevalence of psychiatric disorders in an opioid dependent population maintained on m
Medical maintenance: an interim report.: J Addict Dis. 1994;13(3):65-9. Unique Identifier : AIDSLINE MED/95252235; Senay EC; Barthwell A; Marks R; Bokos PJ; Department of Psychiatry, University of Chicago, USA.; In a pilot study, 130 methadone maintained subjects with a six-month history of good treatment performance were assigned randomly, for a one-year study period, to an experimental condition (once per month non-random urine screen, counseling session and doctor visit, two times per month methadone pick up, a quarterly t
Imipramine for the treatment of cocaine and methamphetamine dependence.: J Addict Dis. 1994;13(4):201-16. Unique Identifier : AIDSLINE MED/95252245; Galloway GP; Newmeyer J; Knapp T; Stalcup SA; Smith D; Drug Detoxification, Rehabilitation, and Aftercare Program,; Haight-Ashbury Free Clinics, San Francisco, CA 94117, USA.; At the Drug Detoxification, Rehabilitation, and Aftercare Program of the Haight-Ashbury Free Clinics, we conducted a double-blind, controlled, randomized clinical trial of imipramine in the treatment of cocaine and methamphetamine abusers. The purpose of the trial was to test the efficacy of imipramine as a treatment
[Vision disorders and ocular lesions in an AIDS patient]: Enferm Infecc Microbiol Clin. 1995 Mar;13(3):183-5. Unique Identifier : AIDSLINE MED/95252276; Aretio R; Garcia A; Vazquez A; Recio F; Corzo JE; Lozano F; Unidad de Enfermedades Infecciosas, Hospital Universitario de; Valme, Sevilla.
Human immunodeficiency virus type 2 (HIV-2): packaging signal and associated negative regulatory element.: Hum Gene Ther. 1995 Feb;6(2):177-84. Unique Identifier : AIDSLINE MED/95252293; Garzino-Demo A; Gallo RC; Arya SK; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, MD 20892, USA.; Human immunodeficiency virus type 2 (HIV-2)-based retroviral vectors will have several desirable features as vehicles for gene therapy. These include target cell specificity, regulated expression, and attenuated cytopathicity. Such vectors require efficient packaging of RNA into retroviral particles which depends on a
Routine HIV testing before surgery [letter]: Aust J Public Health. 1995 Feb;19(1):107-8. Unique Identifier : AIDSLINE MED/95252363; Selvey L; Hogan P; Frazer IH; Smithers M; Robinson D
Heterosexual behaviour and HIV risk in New Zealand: data from a national survey.: Aust J Public Health. 1995 Feb;19(1):13-8. Unique Identifier : AIDSLINE MED/95252365; Paul C; Dickson N; Davis PB; Yee RL; Chetwynd J; McMillan N; Department of Preventive and Social Medicine, University of; Otago, Dunedin.; The pattern of any future major heterosexual epidemic of acquired immunodeficiency syndrome (AIDS) will depend partly on sexual behaviour and condom use among heterosexuals. This survey was designed to provide information on patterns of sexual behaviour in New Zealand . A nation
Health promotion priorities of economically stressed cities.: J Health Care Poor Underserved. 1995;6(1):10-22. Unique Identifier : AIDSLINE MED/95252412; Greenberg M; Schneider D; Martell J; Department of Urban Studies and Community Health, Rutgers; University, New Brunswick, NJ 08903, USA.; The authors surveyed the local health officers (LHOs) of 436 northeastern and midwestern cities about their priorities for promoting health through prevention. LHOs of the most economically stressed cities identified the following as the five most important public health prevention goals that are amenable to intervent
[Treatment of chronic hepatitis C virus infection with interferon in patients infected with the human immunodeficiency virus]: An Med Interna. 1994 Dec;11(12):575-9. Unique Identifier : AIDSLINE MED/95252450; Sanchez JF; Pascua J; Sanchez F; Crespo L; Briones A; Martin C; Unidad de Infecciosas, Hospital Ntra. Sra. de la Montana,; Caceres.; FOUNDATION: We assessed the effectivity of the treatment with interferon (IFN) in patients infected by the human immunodeficiency virus (HIV) with chronic hepatitis (CH) by the hepatitis C virus (HCV). METHODS: We studied 14 heterosexual males ex-parenterally drug consumers (PDC) and infected by the HIV (mean age 26 +
[Serum activity of the lactate dehydrogenase enzyme in patients with human immunodeficiency virus infection]: An Med Interna. 1994 Dec;11(12):580-3. Unique Identifier : AIDSLINE MED/95252451; Valencia ME; Laguna F; Camacho J; Castejon A; Soriano V; Adrados M; Gonzalez Lahoz J; Servicio de Enfermedades Infecciosas, CIC. Instituto de Salud; Carlos III, Madrid.; FOUNDATION: Many patients with infection by the HIV show an increase in the levels of the lactodehydrogenase (LCH) enzyme. In most of these cases, such increase has been associated to the presence of pneumonia by Pneumocystis carinii. In order to analyze other possible causes of this increase, we conducted a study in
[Bilateral avascular necrosis of the femur head in an HIV-positive male]: An Med Interna. 1994 Dec;11(12):601-3. Unique Identifier : AIDSLINE MED/95252457; Manzaneque Gonzalez L; Mayoral Martin L; Jimenez Ocana C; Corzo Delgado JE; Sanchez-Matas Rodriguez P; Grilo Reina A; Servico de Medicina Interna, Hospital Universitario de Valme,; Sevilla.; We present a case of bilateral avascular necrosis at the hips of a HIV-positive male, without other predisposing antecedents. The only relevant analytic data was the positivity of anticardiolipin antibodies (aCL AB). We discuss the possibility that both in this case as in those previously described, HIV may have playe
[An epidemiological study of pulmonary tuberculosis in inpatients]: Aten Primaria. 1995 Mar 31;15(5):297-304. Unique Identifier : AIDSLINE MED/95252475; Fernandez Revuelta A; Arazo Garces P; Aguirre JM; Zalba Etayo B; Lausin Marin S; Servicio de Enfermedades Infecciosas, Hospital Miguel Servet,; Zaragoza.; OBJECTIVE. To evaluate the profile of the patient admitted to hospital with pulmonary tuberculosis and the clinical-radiological signs and symptoms of the illness. DESIGN. A descriptive, retrospective study. SETTING. The study was carried out in the Miguel Servet Hospital in Zaragoza. PATIENTS AND OTHER PARTICIPANTS.
[Intra-abdominal sepsis: surgical management]: Rev Gastroenterol Peru. 1995 Jan-Apr;15(1):62-73. Unique Identifier : AIDSLINE MED/95252501; Vojvodic Hernandez YM; Marroquin Valz HA; Cirujano Asistente Hospital Edgardo Rebagliati-IPSS, Universidad; San Martin de Porres.; Intraabdominal sepsis is a frequent clinical disorder in inpatients with severe consequences as septic shock and multisystem organic failure. It starts with the presence of germs or toxins from the abdominal cavity either intra or retroperitoneal. Pathophysiology is not yet totally understood. Clinical diagnosis many
Cerebral mass lesions associated with adult T-cell leukemia/lymphoma.: Int J Hematol. 1995 Feb;61(2):97-102. Unique Identifier : AIDSLINE MED/95252510; Kawasaki C; Ikeda H; Fukumoto T; Department of Internal Medicine, Sasebo Kyosai Hospital, Japan.; Three patients with adult T-cell leukemia/lymphoma (ATLL) accompanied by cerebral mass lesions in their courses are reported. The findings of cerebrospinal fluid and their history suggested that those three cerebral involvements were the mass lesions derived from ATLL. Two of the three patients had acute type and the
Gay men should not be forgotten [editorial]: J Assoc Nurses AIDS Care. 1995 Jan-Feb;6(1):15-6. Unique Identifier : AIDSLINE MED/95252511; Sowell R
The use of unconventional remedies among HIV-positive men living in California.: J Assoc Nurses AIDS Care. 1995 Jan-Feb;6(1):17-28. Unique Identifier : AIDSLINE MED/95252512; Dwyer JT; Salvato-Schille AM; Coulston A; Casey VA; Cooper WC; Selles WD; Department of Medicine and Community Health, Tufts University; School of Medicine, Boston, MA, USA.; This study compared use of unconventional remedies in two groups of HIV-positive men (N = 63). Employing a multiple-choice questionnaire, the authors assessed the use of and attitudes toward unconventional remedies among two groups of white HIV-positive men similar in age, socioeconomic status, and severity of illness
Comprehensive care and the sanatoria: Cuba's response to HIV/AIDS.: J Assoc Nurses AIDS Care. 1995 Jan-Feb;6(1):33-41. Unique Identifier : AIDSLINE MED/95252513; Swanson JM; Gill AE; Wald K; Swanson KA; Samuel Merritt College, Oakland, CA, USA.; The authors present an overview of Cuba s response to HIV/AIDS including: (a) the development of comprehensive health care in Cuba; (b) the epidemiology of AIDS in Cuba; (c) the sanatoria approach to treatment and recent changes; (d) the idea of comprehensive HIV/AIDS care as a basic human right; (e) the effects of th
Changes in taste associated with intravenous administration of pentamidine [corrected and republished in J Assoc Nurses AIDS Care 1995 Mar-Apr;6(2):41-6]: J Assoc Nurses AIDS Care. 1995 Jan-Feb;6(1):43-8. Unique Identifier : AIDSLINE MED/95252514; Glover J; Dibble S; Miaskowski C; Geibert R; Infusion Center, Kaiser Permanente Medical Group, San Francisco,; CA, USA.; In this pilot study the authors set out to: (a) describe the incidence of taste changes associated with intravenous (i.v.) pentamidine treatment; and (b) determine the factors that are related to making the taste changes better and worse. A convenience sample (N = 18) of adult male outpatients with AIDS participated i
Nursing education and the HIV/AIDS pandemic.: J Assoc Nurses AIDS Care. 1995 Jan-Feb;6(1):49-52. Unique Identifier : AIDSLINE MED/95252515; Hurley PM; McGriff EP; College of Nursing, Rutgers, State University of New Jersey,; Newark, USA.
Let's push for HBO therapy [letter]: J Assoc Nurses AIDS Care. 1995 Jan-Feb;6(1):53-4. Unique Identifier : AIDSLINE MED/95252516; Smith ME
Not only for nurses [letter]: J Assoc Nurses AIDS Care. 1995 Jan-Feb;6(1):54-5. Unique Identifier : AIDSLINE MED/95252517; Carson RW
Confidentially speaking [letter; comment]: J Assoc Nurses AIDS Care. 1995 Jan-Feb;6(1):55. Unique Identifier : AIDSLINE MED/95252518; Garner C
Seroprevalence of HCV, HAV, HBV, HDV, HCMV and HIV in high risk groups/Frankfurt a.M., Germany.: Int J Med Microbiol Virol Parasitol Infect Dis. 1995 Jan;282(1):102-12. Unique Identifier : AIDSLINE MED/95252670; Weber B; Rabenau H; Berger A; Scheuermann EH; Staszewski S; Kreuz W; Scharrer I; Schoeppe W; Doerr HW; Institut fur Medizinische Virologie, Universitatskliniken; Frankfurt.; During the period from August 1991 to April 1993, serum samples originating from different risk groups were tested for antibodies against hepatitis C virus (HCV), using a second-generation ELISA. The highest HCV seroprevalence levels were observed in haemophiliacs (87.0%) and intravenous drug abusers (IVDA) (78.9%). T
Influence of propionibacterium avidum KP-40 on the proliferation, maturation, emigration and activity of thymocytes and monocytes.: Int J Med Microbiol Virol Parasitol Infect Dis. 1995 Jan;282(1):86-91. Unique Identifier : AIDSLINE MED/95252681; Ko HL; Winkler C; Beuth J; Tunggal L; Buss G; Jeljaszewicz J; Klippel KF; Pulverer G; Institut fur Medizinische Mikrobiologie und Hygiene,; Universitat zu Koln, FRG.; Inactivated cells of Propionibacterium avidum KP-40 could be shown to induce thymocyte proliferation and maturation in BALB/c-mice after intraperitoneal administration of the optimal immunomodulating dosage (1 mg per mouse). The increase in thymus weight and thymocyte numbers per mg organ weight was most pronounced an
Computational methods for Markov series with large state spaces, with application to AIDS modeling.: Math Biosci. 1995 May;127(1):99-121. Unique Identifier : AIDSLINE MED/95252709; Yakowitz S; Systems and Industrial Engineering Department, University of; Arizona, Tucson 85721, USA.; AIDS models, and epidemiological models generally, are almost exclusively either differential equations or Markov processes. Of course, the phenomena are fundamentally random, so at best differential equations track the expectation of the process and variability is masked. There are few techniques in the literature fo
Inhibition of in vitro transcription by oligodeoxynucleotides.: Antisense Res Dev. 1994 Winter;4(4):279-84. Unique Identifier : AIDSLINE MED/95252795; Temsamani J; Metelev V; Levina A; Agrawal S; Zamecnik P; Hybridon Inc., Worcester, Massachusetts 01605.; Single-stranded short phosphodiester oligodeoxynucleotides have been used to inhibit in vitro T7 transcription system. These oligodeoxynucleotides were complementary to either the 3 -5 or 5 -3 strand of the transcription initiation site of a plasmid containing the gag region of HIV. Our results show that incubation
HIV-1 rev antisense phosphorothioate oligonucleotide binding to human mononuclear cells is cell type specific and inducible.: Antisense Res Dev. 1994 Winter;4(4):285-9. Unique Identifier : AIDSLINE MED/95252796; Pirruccello SJ; Perry GA; Bock PJ; Lang MS; Noel SM; Zon G; Iversen PL; Department of Pathology and Microbiology, University of Nebraska; Medical Center, Omaha 68198.; A fluorescein-conjugated, antisense phosphorothioate oligonucleotide with specificity for HIV-1 rev sequence (FAM-anti-rev) was investigated for its ability to bind to specific subsets of human peripheral blood mononuclear cells. Oligonucleotide binding by CD4+ and CD8+ T cells, B cells, and monocytes isolated from 15
New insights into the mechanisms of immunotherapy.: Eur Arch Otorhinolaryngol Suppl. 1995;1:S64-7. Unique Identifier : AIDSLINE MED/95252862; Durham SR; Department of Allergy and Clinical Immunology, National Heart &; Lung Institute, London, UK.; Allergen-specific immunotherapy retains a place in treatment in patients with allergic rhinitis who fail to respond to conventional treatment with antihistamines and topical corticosteroids. Studies on mechanisms of immunotherapy have previously focussed on changes in serum antibodies, including blunting of seasonal r
[Mycobacterial pathology in HIV infection]: Pneumoftiziologia. 1994 Jan-Jun;43(1-2):119-26. Unique Identifier : AIDSLINE MED/95252865; Corlan E
[The etiological profile of the pulmonary manifestations in AIDS patients (studies of 65 cases recorded in Romania up to 1 March 1993)]: Pneumoftiziologia. 1994 Jan-Jun;43(1-2):23-8. Unique Identifier : AIDSLINE MED/95252868; Marta D; Caruntu F; Defta D; Banica D; Bercea O; Institutul de Pneumoftiziologie Marius Nasta, Bucuresti.; HIV infection and its final form as AIDS were ignored by the public opinion in Romania till 1990. Nowadays it is real fact in our country. Out of total number of 2235 AIDS cases declared till March 1st 1993 by the Ministry of Health only 134 were adult persons. The study concerns
A review of the literature examining the relationship between alcohol use and HIV-related sexual risk-taking in young people.: Addiction. 1995 Mar;90(3):319-28. Unique Identifier : AIDSLINE MED/95252912; Donovan C; McEwan R; Department of Epidemiology and Public Health, University of; Newcastle, UK.; Young people have been targeted as a potentially vulnerable population for the spread of HIV. The influence of alcohol on sexual behaviour is part of popular knowledge. More recently, studies have attempted to illuminate the relationship between alcohol use and sexual risk-taking in relation to HIV transmission. In ou
Scientific data on HIV transmission [letter; comment] [see comments]: Natl Med J India. 1995 Mar-Apr;8(2):95. Unique Identifier : AIDSLINE MED/95252969; Nandi J
Case management to enhance HIV risk reduction among users of injection drugs and crack cocaine.: J Case Manag. 1994 Winter;3(4):162-6. Unique Identifier : AIDSLINE MED/95252985; Falck R; Carlson RG; Price SK; Turner JA; Case management is being applied to increasingly diverse client populations. This article describes the application of a field-based, service-broker model of case management with a population of injection drug users and crack cocaine users within the context of an AIDS risk-reduction program. The major problem encount
Case management within a methadone maintenance program. A research demonstration project for HIV risk reduction.: J Case Manag. 1994 Winter;3(4):167-72. Unique Identifier : AIDSLINE MED/95252986; Hasson AL; Grella CE; Rawson R; Anglin MD; The Los Angeles Enhanced Methadone Maintenance Project has incorporated case management in order to evaluate its effectiveness in reducing the risk of infection and/or transmission of human immunodeficiency virus among high-risk heroin addicts. Those recruited into the National Institute on Drug Abuse-funded treatment
Case management of substance abusers with HIV disease.: J Case Manag. 1994 Winter;3(4):173-8. Unique Identifier : AIDSLINE MED/95252987; Schwartz B; Dilley J; Sorensen JL; Case management is a promising intervention that has been used widely in many settings but is not well evaluated with substance abusers. This article describes a case management approach for substance abusers with human immunodeficiency virus (HIV) disease. Clients are enrolled from emergency and outpatient clinics of
Study finds AZT reduces HIV transmission rate from mother to infant.: AWHONN Voice. 1994 Oct;2(10):1-2. Unique Identifier : AIDSLINE MED/95253077
Isoniazid chemoprophylaxis for dual HIV-TB infection: a cautionary tale.: Can Commun Dis Rep. 1995 Feb 28;21(4):29-32; discussion 32, 35. Unique Identifier : AIDSLINE MED/95253095; FitzGerald JM; Willow Chest Centre, B.C. Centre for Disease Control, Vancouver.
Molecular parameters for the anti-human immunodeficiency virus activity of T22 ([Tyr5,12, Lys7]-polyphemusin II).: Biol Pharm Bull. 1994 Dec;17(12):1669-72. Unique Identifier : AIDSLINE MED/95253127; Otaka A; Tamamura H; Terakawa Y; Masuda M; Koide T; Murakami T; Nakashima H; Matsuzaki K; Miyajima K; Ibuka T; et al; Faculty of Phamaceutical Sciences, Kyoto University, Japan.; T22 ([Tyr5,12, Lys7]-polyphemusin II) was found to exhibit strong anti-human immunodeficiency virus (HIV) activity and exert its effects on a virus-cell fusion process. In the present study, the all-D enantiomer of T22 and its related compounds were synthesized to examine the molecular parameters required for the inte
Brucella melitensis: an unexpected isolate from cerebrospinal fluid.: Commun Dis Rep CDR Rev. 1995 Mar 31;5(4):R56-7. Unique Identifier : AIDSLINE MED/95253268; Wheat PF; Dabbs DJ; Thickett KJ; Microbiology Department, Royal Hallamshire Hospital.; A specimen of cerebrospinal fluid was initially handled with category 3 precautions because the patient came from Somalia , where tuberculosis and HIV infection are endemic. An isolate from the specimen, initially thought to be a Neisseria species, was subsequently handled on the
Sexually transmitted diseases quarterly report: gonorrhoea in England and Wales.: Commun Dis Rep CDR Wkly. 1995 Mar 31;5(13):62-3. Unique Identifier : AIDSLINE MED/95253274
Manual handling activities and risk of low back pain in nurses.: Occup Environ Med. 1995 Mar;52(3):160-3. Unique Identifier : AIDSLINE MED/95253336; Smedley J; Egger P; Cooper C; Coggon D; MRC Environmental Epidemiology Unit, University of Southampton,; Southampton General Hospital.; OBJECTIVE--To investigate the risk factors for low back pain in hospital nurses, with particular emphasis on the role of specific nursing activities. METHODS--A cross sectional survey of 2405 nurses employed by a group of teaching hospitals was carried out. Self administered questionnaires were used to collect informa
Now is the time for routine voluntary HIV testing of pregnant women [editorial]: Arch Pediatr Adolesc Med. 1995 May;149(5):484-5. Unique Identifier : AIDSLINE MED/95253348; Stiehm ER
Pediatric human immunodeficiency virus infection. Recent evidence on the utilization and costs of health services.: Arch Pediatr Adolesc Med. 1995 May;149(5):489-96. Unique Identifier : AIDSLINE MED/95253349; Hsia DC; Fleishman JA; East JA; Hellinger FJ; Agency for Health Care Policy and Research, Public Health; Service, US Department of Health and Human Services, Rockville,; MD, USA.; OBJECTIVE: To measure the utilization and costs of pediatric human immunodeficiency virus (HIV)-related health care services. DESIGN: Cohort survey. SETTING: Eight outpatient departments serving large numbers of HIV-infected children in five standard metropolitan areas with high prevalence of HIV-infected children. PA
Longitudinal assessment of growth in children born to mothers with human immunodeficiency virus infection.: Arch Pediatr Adolesc Med. 1995 May;149(5):497-502. Unique Identifier : AIDSLINE MED/95253350; Saavedra JM; Henderson RA; Perman JA; Hutton N; Livingston RA; Yolken RH; Department of Pediatrics, Johns Hopkins University School of; Medicine, Baltimore, Md, USA.; OBJECTIVES: To describe and to evaluate the longitudinal growth of children born to mothers with human immunodeficiency virus (HIV) infection. DESIGN: Measurements of weight, length (measured in infants in a recumbent position) and height (measured in older children in an upright position), and head circumference were
Human immunodeficiency virus-specific IgA in infants born to human immunodeficiency virus-seropositive women.: Arch Pediatr Adolesc Med. 1995 May;149(5):503-7. Unique Identifier : AIDSLINE MED/95253351; Livingston RA; Hutton N; Halsey NA; Kline RL; Joyner M; Quinn TC; Department of Pediatrics, Johns Hopkins University School of; Medicine, Baltimore, Md, USA.; OBJECTIVE: To determine the sensitivity and specificity of human immunodeficiency virus (HIV)-specific IgA for vertically transmitted HIV infection, particularly during the first month of life. DESIGN/SETTING/PATIENTS: Prospective cohort study of 140 infants born to HIV-seropositive women in a large urban teaching hos
Street youth in Los Angeles. Profile of a group at high risk for human immunodeficiency virus infection.: Arch Pediatr Adolesc Med. 1995 May;149(5):513-9. Unique Identifier : AIDSLINE MED/95253352; Kipke MD; O'Connor S; Palmer R; MacKenzie RG; Division of Adolescent Medicine, Childrens Hospital, Los Angeles,; Calif, USA.; OBJECTIVE: To characterize an urban street youth population, their self-reported rates of drug use, and their involvement in behaviors that put them at risk for infection with the human immunodeficiency virus. DESIGN: A brief structured interview was administered to 409 youths who had been living on the streets for 2
Teenagers at risk of human immunodeficiency virus type 1 infection. Results from seroprevalence surveys in the United States.: Arch Pediatr Adolesc Med. 1995 May;149(5):521-8. Unique Identifier : AIDSLINE MED/95253353; Sweeney P; Lindegren ML; Buehler JW; Onorato IM; Janssen RS; Division of HIV/AIDS, National Center for Infectious Diseases,; Centers for Disease Control and Prevention, Atlanta, Ga., USA.; OBJECTIVE: To describe the seroprevalence of human immunodeficiency virus type 1 (HIV-1) and risk factors for HIV-1 infection among teenagers attending selected clinics. DESIGN: Anonymous, cross-sectional serosurveys conducted in 130 clinics in 24 cities. SETTINGS: Adolescent medicine clinics, sexually transmitted dis
Newborn human immunodeficiency virus testing in New York: a legislative quandary.: Arch Pediatr Adolesc Med. 1995 May;149(5):581-2. Unique Identifier : AIDSLINE MED/95253365; Bateman DA; Cooper A; Abrams EJ; Harlem Hospital, Newborn Service, New York, NY 10037, USA.
[Retrovirus, hepatitis B and C virus markers in milk and blood donors (letter)]: Arch Pediatr. 1995 Jan;2(1):92. Unique Identifier : AIDSLINE MED/95253387; Moncharmont P
[Maternal-fetal transmission of HIV]: Arch Pediatr. 1995 Feb;2(2):169-72. Unique Identifier : AIDSLINE MED/95253400; Gillet JY; Bongain A; Monpoux F; Mariani R; Service de gynecologie-obstetrique, medicine de la; reproduction et medecine foetale, CHU de Nice-Sophia-Antipolis,; hopital Saint-Roch, France.; HIV infection in children is mainly the result of a mother-to-child transmission. The contamination during pregnancy is well known but intrapartum vertical transmission may also occur through ascending infection, blood exchange between mother and child, or direct contact with vaginal or cervical secretions. In additio
High-performance liquid chromatographic determination of the antifungal drug fluconazole in plasma and saliva of human immunodeficiency virus-infected patients.: J Chromatogr B Biomed Appl. 1995 Jan 20;663(2):345-51. Unique Identifier : AIDSLINE MED/95253432; Koks CH; Rosing H; Meenhorst PL; Bult A; Beijnen JH; Department of Pharmacy, Slotervaart Hospital, Amsterdam,; Netherlands.; A high-performance liquid chromatographic (HPLC) assay has been developed for the determination of the antifungal drug fluconazole in saliva and plasma of patients infected with the human immunodeficiency virus (HIV). Samples can be heated at 60 degrees C for 30 min to inactivate the virus without loss of the analyte.
Comprehensive tuberculosis control for patients at high risk for noncompliance.: Am J Respir Crit Care Med. 1995 May;151(5):1486-90. Unique Identifier : AIDSLINE MED/95253559; Schluger N; Ciotoli C; Cohen D; Johnson H; Rom WN; Bellevue Chest Service, New York University Medical Center, New; York, USA.; The current tuberculosis epidemic in the United States is marked, in many areas, by high rates of noncompliance with antituberculous regimens. In response to this, a comprehensive program of medical, nursing, social services, and supervised therapy was developed at Bellevue Hospital. M
AIDS and nursing: psychological and legal issues.: J Nurs Manag. 1995 Mar;3(2):93-6. Unique Identifier : AIDSLINE MED/95253615; Dionne-Proulx J
Anticipated affective reactions and prevention of AIDS.: Br J Soc Psychol. 1995 Mar;34 ( Pt 1):9-21. Unique Identifier : AIDSLINE MED/95253704; Richard R; van der Pligt J; de Vries N; University of Amsterdam, Faculty of Psychology, Department of; Social Psychology, The Netherlands.; Controlling the AIDs epidemic may depend largely upon health education aimed at adolescents. A number of approaches have been applied to human immunodeficiency virus (HIV) preventive behaviour in adolescents, including the health belief model (Becker, 1974), protection motivation theory (Rogers, 1983), and the theory
Recombining the structures of HIV integrase, RuvC and RNase H.: Structure. 1995 Feb 15;3(2):131-4. Unique Identifier : AIDSLINE MED/95253812; Yang W; Steitz TA; Department of Molecular Biophysics and Biochemistry, Howard; Hughes Medical Institute, Yale University, New Haven, CT 06520,; USA.; The recently reported crystal structures of two recombination enzymes, the catalytic domain of HIV integrase and Escherichia coli RuvC, an endonuclease, are surprisingly similar to that of ribonuclease H suggesting the possibility that they have a common enzymatic mechanism.
AIDS and discrimination [letter; comment] [see comments]: J Can Dent Assoc. 1995 Apr;61(4):277, 350. Unique Identifier : AIDSLINE MED/95254370; Stein MH
[Oral candidiasis: diagnosis and drug therapy]: J Can Dent Assoc. 1995 Apr;61(4):340-4, 347-50. Unique Identifier : AIDSLINE MED/95254376; Nguyen NT; Lalonde B; Faculte de Medecine dentaire, Universite de Montreal.; Oral candidiasis is the most frequently observed oral mycosis. It can be manifested as a variety of clinical symptoms, and both local and systemic factors may contribute to its development. A confirmation of this infection depends upon the use of appropriate diagnostic tests, in addition to the presence of clinical si
An Italian survey on how information campaigns about AIDS have changed contraception in young couples. A sectional study and a comparison with the literature.: Clin Exp Obstet Gynecol. 1995;22(1):32-5. Unique Identifier : AIDSLINE MED/95254717; Aboulkhair MN; Unfer V; Costabile L; II Institute of Gynaecology and Obstetrics, University La; Sapienza, Rome.; The purpose of the present investigation was to ascertain whether adolescent had been sensitized by the campaign against AIDS and if their behaviour regarding the use of contraception had changed accordingly. To this end 2,000 questionnaires (of which 1,554 were returned) were distributed to a population aged 13-20 ye
Vulvo-vaginitis and reproduction.: Clin Exp Obstet Gynecol. 1995;22(1):51-65. Unique Identifier : AIDSLINE MED/95254722; Pellicano M; Castellano A; Magri G; Vigorito R; Carnevale E; De Falco D; Iorio F; Landri U; Department of Obstetrics and Gynecology, Capri Hospital, Naples,; Italy.; The main micro-organisms able to interfere with the reproductive function have been considered. In particular, the problems concerning the vaginal environment and its interactions with spermatozoa, immunological aspects and contraception. Lastly, reference has been made to methods of prevention and study in the field
Clinical pharmacokinetics of rifabutin.: Clin Pharmacokinet. 1995 Feb;28(2):115-25. Unique Identifier : AIDSLINE MED/95254767; Skinner MH; Blaschke TF; Division of Clinical Pharmacology, University of Texas, Health; Science Center at San Antonio, USA.; The clinical effectiveness of rifabutin for prophylaxis of disseminated Mycobacterium avium complex infection has recently been demonstrated in HIV-positive patients with low CD4 counts. Rifabutin is a newly marketed, semisynthetic antimycobacterial agent similar to rifampicin (rifampin) in structure and activity. How
A SAS macro for residual deviance of ordinal regression analysis.: Comput Methods Programs Biomed. 1994 Dec;45(4):307-10. Unique Identifier : AIDSLINE MED/95254816; Wan JY; Wang W; Bromberg J; Division of Biostatistics and Epidemiology, University of; Tennessee, Memphis 38163, USA.; In this paper, a SAS macro is described for calculating the likelihood of the saturated model in the analysis of ordinal regression. The outcome variable is multinomial on an ordinal scale, while the explanatory variables can be nominal or ordinal. Several ordinal regression models may be fitted to the data. One met
On computers and building blocks, APACHE II and HIV, and dark clouds [editorial; comment]: Crit Care Med. 1995 May;23(5):797-8. Unique Identifier : AIDSLINE MED/95254819; Franklin C; Layon AJ
Predictive ability of acute physiology and chronic health evaluation II scoring applied to human immunodeficiency virus-positive patients [see comments] [published erratum appears in Crit Care Med 1995 Aug;23(8):1454]: Crit Care Med. 1995 May;23(5):848-53. Unique Identifier : AIDSLINE MED/95254829; Brown MC; Crede WB; Yale University School of Medicine, New Haven, CT, USA.; OBJECTIVE: To evaluate the predictive ability of the Acute Physiology and Chronic Health Evaluation II (APACHE II) prognostic scoring system when applied to human immunodeficiency virus (HIV) seropositive patients in the medical intensive care unit (ICU). DESIGN: A retrospective chart review. SETTING: An urban univers
Ethnobotany and drug discovery: the experience of the US National Cancer Institute.: Ciba Found Symp. 1994;185:178-90; discussion 190-6. Unique Identifier : AIDSLINE MED/95254943; Cragg GM; Boyd MR; Cardellina JH 2nd; Newman DJ; Snader KM; McCloud TG; Developmental Therapeutics Program, National Cancer Institute,; Bethesda, Maryland 20892.; Between 1960 and 1981 the National Cancer Institute (NCI) screened 114,000 extracts of 35,000 plants, mainly collected in temperate regions. Of the three clinically active anticancer drugs so far discovered in that programme, none was isolated from a plant collected on an ethnobotanical basis, though various Taxus spe
The ethnobotanical approach to drug discovery: strengths and limitations.: Ciba Found Symp. 1994;185:25-36; discussion 36-41. Unique Identifier : AIDSLINE MED/95254948; Cox PA; Department of Botany & Range Science, Brigham Young University,; Provo, Utah 84602.; For pharmaceuticals ranging from digitalis to vincristine the ethnobotanical approach to drug discovery has proven successful. The advent of high-throughput, mechanism-based in vitro bioassays coupled with candidate plants derived from pain-staking ethnopharmacological research has resulted in the discovery of new pha
Ethnobotany, drug development and biodiversity conservation--exploring the linkages.: Ciba Found Symp. 1994;185:4-18; discussion 18-24. Unique Identifier : AIDSLINE MED/95254949; Balick MJ; Institute of Economic Botany, New York Botanical Garden, Bronx; 10458.; Numerous ethnobotanical studies aimed at identifying new pharmaceutical products have been initiated in recent times. Ethnobotany has once again become a recognized tool in the search for new pharmaceuticals. Initiatives by governmental agencies and the private sector have helped spark this renewal. Many of these proj
Metabolism of L-689,502 by rat liver slices to potent HIV-1 protease inhibitors.: Drug Metab Dispos. 1995 Feb;23(2):185-9. Unique Identifier : AIDSLINE MED/95255002; Balani SK; Pitzenberger SM; Schwartz MS; Ramjit HG; Thompson WJ; Department of Drug Metabolism, Merck Research Laboratories, West; Point, PA 19486, USA.; L-689,502, N-[2(R)-hydroxy-1(S)-indanyl]-5(S)-(1,1-dimethylethoxy- carbonyl-amino)-4(S)-hydroxy-6-phenyl-2(R)-(4-[2(R)-(4-morpholiny- l) ethoxy]phenyl)methylhexamide, is a potent and specific inhibitor of human immunodeficiency virus-type 1 (HIV-1) protease in vitro. Metabolism of this compound in rat liver slices pro
Metabolites of L-735,524, a potent HIV-1 protease inhibitor, in human urine.: Drug Metab Dispos. 1995 Feb;23(2):266-70. Unique Identifier : AIDSLINE MED/95255016; Balani SK; Arison BH; Mathai L; Kauffman LR; Miller RR; Stearns RA; Chen IW; Lin JH; Department of Drug Metabolism, Merck Research Laboratories, West; Point, PA 19486, USA.; L-735,524, N-[2(R)-hydroxy-1(S)-indanyl]-5-(2(S)-(1,1- dimethylethylaminocarbonyl)-4-[(pyridin-3-yl)methyl]piperazin++ +-1-yl)-4(S)- hydroxy-2(R)-phenylmethylpentanamide, is a potent and specific inhibitor of the human immunodeficiency virus type 1 protease and is undergoing clinical evaluation. In an initial clinical
[Sinusitis in HIV infection]: Dtsch Med Wochenschr. 1994 Dec 23;119(51-52):1759-65. Unique Identifier : AIDSLINE MED/95255022; Stuck M; Hachler I; Luthy R; Ruef C; Abteilung Infektionskrankheiten und Spitalhygiene,; Universitatsspital Zurich.; Case notes of 722 HIV-infected patients who had died between March 1986 and August 1993 were analysed to evaluate the prevention and characteristic features of sinusitis associated with HIV infection. In 73 patients (10%) sinusitis had been diagnosed at least once on the basis of radiological or clear-cut clinical cri
[HIV transmission in heterosexual partners]: Dtsch Med Wochenschr. 1994 Dec 23;119(51-52):1805. Unique Identifier : AIDSLINE MED/95255035
A preliminary evaluation of the cognitive and motor effects of pediatric HIV infection in Zairian children.: Health Psychol. 1995 Jan;14(1):13-21. Unique Identifier : AIDSLINE MED/95255168; Boivin MJ; Green SD; Davies AG; Giordani B; Mokili JK; Cutting WA; Department of Psychology, Spring Arbor College, Michigan 49283,; USA.; Fourteen asymptomatic HIV-infected Zairian children under 2 years of age displayed social and motor developmental deficits on the Denver Developmental Screening Test when compared with 20 HIV-negative cohorts born to HIV-infected mothers and 16 control children. In a second study, 11 infected children over 2 years of
Multiple sexual partners and their psychosocial correlates: the population-based AIDS in multiethnic neighborhoods (AMEN) study.: Health Psychol. 1995 Jan;14(1):22-31. Unique Identifier : AIDSLINE MED/95255169; Dolcini MM; Coates TJ; Catania JA; Kegeles SM; Hauck WW; Department of Medicine, University of California, San Francisco; 94105, USA.; In this study we examined multiple partners in a household probability sample of heterosexuals. Thirty-seven percent reported 2 or more partners in the past year, and 6% reported 5 or more partners. Significant interactions among gender, ethnicity, and relationship status revealed complex relations. African American m
Research on disclosure of HIV status: cultural evolution finds an ally in science [comment]: Health Psychol. 1995 Jan;14(1):4-5. Unique Identifier : AIDSLINE MED/95255171; Szapocznik J; Spanish Family Guidance Center, University of Miami, Florida,; USA.; This editorial responds to Mason et al. s (1995) Culturally Sanctioned Secrets: Latino Men s Nondisclosure of HIV Infection to Family, Friends, and Lovers. Culture is an evolving dynamic phenomenon shaped by society, psychology, and history. Historically, familism and simpatia have been Hispanic cultural assets. As ti
Culturally sanctioned secrets? Latino men's nondisclosure of HIV infection to family, friends, and lovers [see comments]: Health Psychol. 1995 Jan;14(1):6-12. Unique Identifier : AIDSLINE MED/95255175; Mason HR; Marks G; Simoni JM; Ruiz MS; Richardson JL; Department of Preventive Medicine, University of Southern; California, Los Angeles 90033-1042, USA.; Spanish-speaking Latino men (n = 107) were more likely than English-speaking Latinos (n = 85) and Whites (n = 206) to withhold their HIV-positive serostatus and their gay or bisexual orientation from significant others, especially family members. Similar effects were observed when Latinos were divided by birthplace an
A new cationic liposome encapsulating genetic material. A potential delivery system for polynucleotides.: Eur J Biochem. 1995 Mar 15;228(3):697-703. Unique Identifier : AIDSLINE MED/95255274; Puyal C; Milhaud P; Bienvenue A; Philippot JR; URA 1856 CNRS, CP 107, Universite Montpellier II, France.; The endeavour to enhance gene therapy has led to increased research on the development of simple, efficient and safe delivery systems. This study deals with the use of an artificial cationic lipid on the encapsulation of genetic material in liposomes. The addition of a biologically degradable cationic phospholipid, di
The gag homologue of retrotransposon Ty1 assembles into spherical particles in Escherichia coli.: Eur J Biochem. 1995 Mar 15;228(3):739-44. Unique Identifier : AIDSLINE MED/95255280; Luschnig C; Hess M; Pusch O; Brookman J; Bachmair A; Department of Cytology and Genetics, University of Vienna,; Austria.; Expression of TyA (reading frame A) of the yeast retrotransposon Ty1 in Escherichia coli is possible by using efficient transcriptional and translational initiation signals. When expressed in E. coli, the gag homologue of Ty1 assembles into spherical particles similar, but not identical to virus-like particles in the
Left ventricular diastolic function in asymptomatic and symptomatic human immunodeficiency virus carriers: an echocardiographic study.: Eur Heart J. 1995 Jan;16(1):61-7. Unique Identifier : AIDSLINE MED/95255332; Coudray N; de Zuttere D; Force G; Champetier de Ribes D; Pourny JC; Antony I; Lecarpentier Y; Chemla D; Inserm U275, Loa-Ensta-Ecole Polytechnique, Palaiseau, France.; Acquired immunodeficiency syndrome (AIDS) is a systemic illness affecting multiple organs, including the heart. Left ventricular (LV) diastolic dysfunction has been reported as the first echocardiographically detectable abnormality in several cardiovascular disorders. We tested the hypothesis that Human Immunodeficien
Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway.: Eur J Immunol. 1995 Apr;25(4):1071-9. Unique Identifier : AIDSLINE MED/95255392; Isaaz S; Baetz K; Olsen K; Podack E; Griffiths GM; Basel Institute for Immunology, Switzerland.; CD8+ cytotoxic T lymphocyte (CTL) clones begin to synthesize the lytic proteins granzyme A, granzyme B and perforin after stimulation with allogeneic target cells. The lytic proteins are stored in the secretory granules which are released after cross-linking of the T cell receptor (TcR) upon target cell recognition. D
Activation of virus-specific major histocompatibility complex class II-restricted CD8+ cytotoxic T cells in CD4-deficient mice.: Eur J Immunol. 1995 Apr;25(4):1109-12. Unique Identifier : AIDSLINE MED/95255398; Heemskerk MH; Schilham MW; Schoemaker HM; Spierenburg G; Spaan WJ; Boog CJ; Institute of Infectious Diseases and Immunology, Faculty of; Veterinary Medicine, University of Utrecht, The Netherlands.; Acute enteritic or respiratory disease is a consequence of coronavirus infection in man and rodents. Mouse hepatitis virus, stain A59 (MHV-A59) causes acute hepatitis in mice and rats and induces a response of major histocompatibility complex (MHC) class II-restricted CD4+ cytotoxic T cells, protecting mice against ac
Simple strategy to induce antibodies of distinct specificity: application to the mapping of gp120 and inhibition of HIV-1 infectivity.: Eur J Immunol. 1995 Apr;25(4):877-83. Unique Identifier : AIDSLINE MED/95255406; Prieto I; Hervas-Stubbs S; Garcia-Granero M; Berasain C; Riezu-Boj JI; Lasarte JJ; Sarobe P; Prieto J; Borras-Cuesta F; Universidad de Navarra, Facultad de Medicina, Departamento de; Medicina Interna, Pamplona, Spain.; In this study 96 15-mer peptides encompassing the entire sequence of HIV-1 gp120 were synthesized and used to immunize BALB/c mice (i) alone or (ii) in conjunction with the T helper cell determinant FISEAIIHVLHSR (FIS) from sperm whale myoglobin, which is well recognized by major histocompatibility complex (MHC) class
Diminished responsiveness of senescent normal human fibroblasts to TNF-dependent proliferation and interleukin production is not due to its effect on the receptors or on the activation of a nuclear factor NF-kappa B.: Exp Cell Res. 1995 May;218(1):381-8. Unique Identifier : AIDSLINE MED/95255516; Aggarwal BB; Totpal K; LaPushin R; Chaturvedi MM; Pereira-Smith OM; Smith JR; Department of Clinical Immunology and Biological Therapy,; University of Texas M. D. Anderson Cancer Center, Houston 77030,; USA.; The limited life span in culture of normal human diploid fibroblasts (HDF) has provided a model of cellular senescence. The short-term growth of these cells in culture is regulated by a number of different cytokines, including tumor necrosis factor (TNF), interleukin-1 (IL-1), and fibroblast growth factor (FGF). Howev
Sendai virus and herpes virus type 1 induce apoptosis in human peripheral blood mononuclear cells.: Exp Cell Res. 1995 May;218(1):63-70. Unique Identifier : AIDSLINE MED/95255523; Tropea F; Troiano L; Monti D; Lovato E; Malorni W; Rainaldi G; Mattana P; Viscomi G; Ingletti MC; Portolani M; et al; Department of Biomedical Sciences, University of Modena, Italy.; Recent reports suggest that several viruses, besides human immunodeficiency virus, induce apoptosis in infected cells. We report here that Sendai virus or Herpes simplex virus type 1 (HSV-1), two potent inducers of interferon-alpha, caused cell death in a consistent number of human peripheral blood mononuclear cells.
The other AIDS crisis [editorial]: FASEB J. 1995 Apr;9(7):467. Unique Identifier : AIDSLINE MED/95255598; Edgington TS
Testosterone replacement therapy in HIV illness.: Gen Hosp Psychiatry. 1995 Jan;17(1):37-42. Unique Identifier : AIDSLINE MED/95255641; Rabkin JG; Rabkin R; Wagner G; New York State Psychiatric Institute, NY 10032, USA.; The purpose of this study was to determine whether testosterone replacement therapy ameliorates sexual dysfunction and associated problems of mood, energy, and appetite in HIV+ men with immune suppression (CD4
Humoral response to influenza hemagglutinin: oligoclonal spectrotype and failure of thymopentin as immunoadjuvant.: Gerontology. 1995;41(1):3-10. Unique Identifier : AIDSLINE MED/95255685; Biselli R; Fagiolo U; Nisini R; Paganelli R; D'Offizi G; Ferrara R; Bertollo L; D'Amelio R; Istituto di Medicina Interna, Universita di Padova, Italia.; Influenza remains a serious cause of illness and death among certain populations. Influenza vaccines in use at present are of limited effectiveness due to the high variability of the virus, and trials all over the world are in progress to enhance their immunogenicity. Conflicting results, in fact, have been reported a
[Laboratory diagnosis of HIV infection]: Fortschr Med. 1995 Apr 10;113(10):135-9. Unique Identifier : AIDSLINE MED/95255778; Wagner R; Mayer J; Reischl U; Institut fur medizinische Mikrobiologie und Hygiene,; Universitat Regensburg.; Recent use of modern methods in the field of molecular biology has provided new insights into the genetic and structural nature of HIV, which are now increasingly being applied to the diagnostic work-up. For the reliable laboratory diagnosis of HIV infection, three different possibilities are available: detection of s
Permissiveness of Kupffer cells for simian immunodeficiency virus (SIV) and morphological changes in the liver of rhesus monkeys at different periods of SIV infection.: Hepatology. 1995 May;21(5):1215-25. Unique Identifier : AIDSLINE MED/95255788; Persidsky Y; Steffan AM; Gendrault JL; Hurtrel B; Berger S; Royer C; Stutte HJ; Muchmore E; Aubertin AM; Kirn A; Unite INSERM, Institut de Virologie de la Faculte de Medecine,; Strasbourg, France.; The pathogenesis of liver injury, which remains unclear in the course of human immunodeficiency virus infection, can be investigated in simian immunodeficiency virus-infected macaques, which develop an immunodeficiency disease resembling human acquired immune deficiency syndrome (AIDS). We studied the livers of 21 mon
The immunological potential of apoptotic debris produced by tumor cells and during HIV infection.: Immunol Lett. 1994 Dec;43(1-2):125-32. Unique Identifier : AIDSLINE MED/95255863; Kornbluth RS; Department of Medicine, University of California San Diego, La; Jolla 92093.; Apoptosis is a major cause of cell death in health and disease. In contrast to necrosis, apoptosis does not induce an inflammatory response and the cellular debris produced by apoptosis has been assumed to be biologically inert. This review challenges this assumption by suggesting that apoptotic debris (especially in
Dendritic cells from HIV-1 infected individuals show reduced capacity to stimulate autologous T-cell proliferation.: Immunol Lett. 1994 Dec;43(1-2):39-43. Unique Identifier : AIDSLINE MED/95255869; Roberts M; Gompels M; Pinching AJ; Knight SC; Antigen Presentation Research Group, St Mary's Hospital Medical; School, Northwick Park Institute for Medical Research, Harrow,; UK.; Dendritic cells (DC) exposed for a short period of time (1 day) in vitro to HIV infection caused stimulation of autologous T-cells, but those exposed for a longer period (3 days) before addition to T-cells stimulate little or no proliferation [1]. Since a proportion of DC from patients who are HIV-1 seropositive is in
HIV infection and tuberculosis [editorial]: Indian J Chest Dis Allied Sci. 1994 Jul-Sep;36(3):109-11. Unique Identifier : AIDSLINE MED/95255879; Sharma SK; Pande JN
Pleural involvement in HIV infection: clinico-radiological profile and prognostic significance.: Indian J Chest Dis Allied Sci. 1994 Jul-Sep;36(3):113-7. Unique Identifier : AIDSLINE MED/95255880; Arora VK; Gowrinath K; Rao RS; Department of Tuberculosis and Chest Diseases, Jawaharlal; Institute of Postgraduate Medical Education and Research,; Pondicherry.; The clinico-radiological profile of seven patients with pleural involvement and HIV infection is presented. Five out of seven subjects had a right-sided effusion. The aetiology in three cases; two tubercular and one invasive candidiasis was established by pleural biopsy. The mortality was high (5/7) indicating a poor
Visceral leishmaniasis with cutaneous and rectal dissemination due to Leishmania braziliensis in acquired immunodeficiency syndrome (AIDS).: Int J Dermatol. 1995 Feb;34(2):114-5. Unique Identifier : AIDSLINE MED/95255953; Hernandez DE; Oliver M; Martinez C; Planas G; Department of Medicine, Hospital Vargas, School of Medicine,; Universidad Central de Venezuela, Caracas.
[Diagnosis of tuberculosis and mycobacterioses]: Internist (Berl). 1995 Feb;36(2):120-4. Unique Identifier : AIDSLINE MED/95255986; Bottger EC; Institut fur Medizinische Mikrobiologie, Medizinische Hochschule; Hannover.
[Diagnosis of gastrointestinal infections]: Internist (Berl). 1995 Feb;36(2):151-7. Unique Identifier : AIDSLINE MED/95255992; Stallmach A; Schneider T; Zeitz M; Medizinische Klinik und Poliklinik der Universitatskliniken des; Saarlandes.
[Laboratory diagnosis of infections of the central nervous system]: Internist (Berl). 1995 Feb;36(2):158-61. Unique Identifier : AIDSLINE MED/95255993; Nau R; Prange HW; Neurologische Universitatsklinik Gottingen.
[Fever in immunosuppressed patients]: Internist (Berl). 1995 Feb;36(2):162-9. Unique Identifier : AIDSLINE MED/95255994; Schrappe M; Salzberger B; Klinik I fur Innere Medizin, Universitatsklinik Koln.
The hospital in-patient enquiry scheme: a study of data accuracy and capture.: Ir Med J. 1995 Jan-Feb;88(1):24-6. Unique Identifier : AIDSLINE MED/95256024; Mehanni M; Loughman E; Allwright SP; Prichard J; Department of Community Health and General Practice, University; of Dublin, Trinity College.; In order to measure the coverage and accuracy of the Hospital In-patient Enquiry Scheme data in a large acute hospital in Dublin, 793 patient charts were selected randomly from all the discharges in 1990. The capture rate was 56%. Whether a diagnosis was captured for the Hospital In-patient Enquiry Scheme depended par
Increased prevalence of HTLV-I infection in patients with hepatocellular carcinoma associated with hepatitis C virus.: Jpn J Cancer Res. 1995 Jan;86(1):1-4. Unique Identifier : AIDSLINE MED/95256109; Okayama A; Maruyama T; Tachibana N; Hayashi K; Kitamura T; Mueller N; Tsubouchi H; Second Department of Internal Medicine, Miyazaki Medical School.; The progression from chronic hepatitis C virus (HCV) infection to hepatocellular carcinoma (HCC) has been reported. We evaluated whether co-infection with the human T-lymphotropic virus type I (HTLV-I) might be associated with this transition in a cross-sectional analysis of 127 patients with HCV-chronic hepatitis (me
Human alveolar macrophages augment natural killer cell stimulatory factor (interleukin-12)-inducible killer activity from autologous blood lymphocytes.: Jpn J Cancer Res. 1995 Jan;86(1):81-7. Unique Identifier : AIDSLINE MED/95256125; Haku T; Sone S; Nabioullin R; Ogura T; Third Department of Internal Medicine, University of Tokushima; School of Medicine.; Interleukin-12 (IL-12), also known as natural killer cell stimulatory factor (NKSF), was found to induce cytotoxic activity from human blood T cells and NK cells. The present study was undertaken to examine the effect of human alveolar macrophages (AM) on induction by IL-12 cytotoxic cells from blood lymphocytes. AM w
Transfusion-transmitted retrovirus infection.: Hematol Oncol Clin North Am. 1995 Feb;9(1):115-36. Unique Identifier : AIDSLINE MED/95256159; Williams AE; Sullivan MT; American Red Cross, Jerome H. Holland Laboratory, Rockville,; Maryland, USA.; This article reviews the history, classification, and disease associations of the known human retroviruses and outlines their profound effects on the practice of transfusion medicine. The immunodeficiency viruses, HIV-1 and HIV-2, produce a cytolytic effect on infected lymphocytes, and are the causative agents of AIDS
Cellular gene therapy.: Hematol Oncol Clin North Am. 1995 Feb;9(1):91-113. Unique Identifier : AIDSLINE MED/95256168; Lee JH; Klein HG; Department of Transfusion Medicine, Warren G. Magnuson Clinical; Center, National Institutes of Health, Bethesda, Maryland, USA.; During the last decade, molecular genetic techniques have been used increasingly to transfer human genes into mammalian cells, to correct and enhance cell function, and finally to treat human disease. Despite the current obstacles to developing even the simplest therapeutic strategy, gene therapy promises to have an a
Arkansas HIV/AIDS report 1983-1995.: J Ark Med Soc. 1995 Apr;91(11):572-3. Unique Identifier : AIDSLINE MED/95256175
The development of PCR based assays for the detection and differentiation of simian immunodeficiency virus in vivo.: J Virol Methods. 1995 Feb;51(2-3):229-39. Unique Identifier : AIDSLINE MED/95256394; Rose J; Silvera P; Flanagan B; Kitchin P; Almond N; NIBSC, Potters Bar, Herts, UK.; Polymerase chain reaction based assays, which amplify a region of the gag gene, have been developed for the direct detection of simian immunodeficiency virus (SIV) DNA sequences in the blood of experimentally infected cynomolgus macaques. In macaques infected with a characterised virus pool (11/88 pool SIVmac 32H), an
A non-radioactive multiprime sequencing method for HIV genomes.: J Virol Methods. 1995 Feb;51(2-3):259-66. Unique Identifier : AIDSLINE MED/95256397; Huber J; Hell W; Wolf H; Institute for Medical Microbiology, University of Regensburg,; Germany.; A manual non-radioactive DNA sequencing protocol was developed for rapid analysis of variable HIV-1 genomes. Sets of up to ten primers were used in one sequencing reaction. After polyacrylamide gel electrophoresis and blotting onto nylon membranes the individual sequences were detected by hybridization with digoxigeni
Selection of a monoclonal antibody specific for variant B human herpesvirus 6-infected mononuclear cells.: J Virol Methods. 1995 Feb;51(2-3):289-96. Unique Identifier : AIDSLINE MED/95256400; Foa-Tomasi L; Avitabile E; Campadelli-Fiume G; Department of Experimental Pathology, University of Bologna,; Italy.; A monoclonal antibody, designated as MAb 6E2, specific for human herpesvirus 6 variant B (HHV-6B) was derived from the spleen of a mouse immunized with lysates of HHV-6B(Z29) cord blood mononuclear cells. MAb 6E2 reacts by immunofluorescence with all the HIV-6B strains tested (Z29, CV, Hashimoto and SF) and fails to r
Standardisation of primers and an algorithm for HIV-1 diagnostic PCR evaluated in patients harbouring strains of diverse geographical origin. The Belgian AIDS Reference Laboratories.: J Virol Methods. 1995 Feb;51(2-3):305-16. Unique Identifier : AIDSLINE MED/95256402; Vandamme AM; Fransen K; Debaisieux L; Marissens D; Sprecher S; Vaira D; Vandenbroucke AT; Verhofstede C; Katholieke Universiteit Leuven, Rega Instituut, Belgium.; Eight Belgian AIDS Reference Laboratories established a multicentre quality control to evaluate the performance of their diagnostic human immunodeficiency virus type 1 (HIV-1) DNA polymerase chain reaction (PCR). A set of Belgian and African HIV-1 seropositive and seronegative patient samples, collected in
Altered representation of naive and memory CD8 T cell subsets in HIV-infected children.: J Clin Invest. 1995 May;95(5):2054-60. Unique Identifier : AIDSLINE MED/95256425; Rabin RL; Roederer M; Maldonado Y; Petru A; Herzenberg LA; Herzenberg LA; Department of Genetics, Stanford University School of Medicine,; California 94305, USA.; CD8 T cells are divided into naive and memory subsets according to both function and phenotype. In HIV-negative children, the naive subset is present at high frequencies, whereas memory cells are virtually absent. Previous studies have shown that the overall number of CD8 T cells does not decrease in HIV-infected chil
CD8 naive T cell counts decrease progressively in HIV-infected adults.: J Clin Invest. 1995 May;95(5):2061-6. Unique Identifier : AIDSLINE MED/95256426; Roederer M; Dubs JG; Anderson MT; Raju PA; Herzenberg LA; Herzenberg LA; Department of Genetics, Stanford University School of Medicine,; California 94305, USA.; We show here that CD8 naive T cells are depleted during the asymptomatic stage of HIV infection. Although overall CD8 T cell numbers are increased during this stage, the naive CD8 T cells are progressively lost and fall in parallel with overall CD4 T cell counts. In addition, we show that naive CD4 T cells are prefere
Mycobacterium tuberculosis enhances human immunodeficiency virus-1 replication by transcriptional activation at the long terminal repeat.: J Clin Invest. 1995 May;95(5):2324-31. Unique Identifier : AIDSLINE MED/95256458; Zhang Y; Nakata K; Weiden M; Rom WN; Department of Medicine, New York University Medical Center, New; York 10016, USA.; Tuberculosis has emerged as an epidemic fueled by the large number of individuals infected with the human immunodeficiency virus, especially those who are injecting drug users. We found a striking increase from 4- to 208-fold in p24 levels in bronchoalveolar lavage fluid from involved sites of Mycobacterium tuberculos
Improving the diagnosis of hypersensitivity reactions associated with sulfonamides.: J Clin Pharmacol. 1994 Dec;34(12):1228-33. Unique Identifier : AIDSLINE MED/95256489; Lanctot KL; Ghajar BM; Shear NH; Naranjo CA; Psychopharmacology Research Program, Sunnybrook Health Science; Centre, Toronto, Ontario, Canada.; The differential diagnosis of idiosyncratic adverse drug reactions (ADRs) is difficult because symptoms are seldom pathognomonic. The authors compared the performance of two new diagnostic aids in the differential diagnosis of 27 cases of skin reactions associated with sulfonamide therapy. One test, the Bayesian Adver
[Cytomegalovirus retinitis in children with AIDS acquired through materno-fetal transmission]: J Fr Ophtalmol. 1995;18(2):91-5. Unique Identifier : AIDSLINE MED/95256589; Bremond-Gignac D; Aron-Rosa D; Rohrlich P; Deplus S; Faye A; Vilmer E; Service d'Ophtalmologie, Hopital Robert Debre, Paris.; PURPOSE: To describe the clinical feature and the outcome of CMV retinitis in children with vertically transmitted HIV infection. RESULTS: Five case-reports of cytomegalovirus retinopathy are described. These children from ei
Is the dermal papilla a primary target in alopecia areata?: J Invest Dermatol. 1995 May;104(5 Suppl):7S-8S. Unique Identifier : AIDSLINE MED/95256688; Randall VA; Hull SP; Nutbrown M; Calver NS; Parkin SM; Cunliffe WJ; Department of Biomedical Sciences, University of Bradford, West; Yorkshire, UK.
HIV-related information and the tension between confidentiality and liberal discovery. The need for a uniform approach.: J Leg Med. 1995 Mar;16(1):33-100. Unique Identifier : AIDSLINE MED/95256740; Colella U
The moral significance of AIDS.: J Med Philos. 1994 Dec;19(6):519-24. Unique Identifier : AIDSLINE MED/95256756; Murphy TF; Walters L; Department of Medical Education, University of Illinois College; of Medicine, Chicago 60612-7309, USA.
Informed consent and anonymous tissue samples: the case of HIV seroprevalence studies.: J Med Philos. 1994 Dec;19(6):525-52. Unique Identifier : AIDSLINE MED/95256757; Kopelman LM; Department of Medical Humanities, School of Medicine, East; Carolina University, Greenville, NC 27858-4354, USA.; Human Immunodeficiency Virus (HIV) seroprevalence studies use anonymous tissue samples obtained in hospitals and clinics without donor consent. This can be justified as a response to a public health emergency, but should not be seen as setting a precedent for waiving consent whenever samples are anonymous. The followi
Health care workers with HIV and a patient's right to know.: J Med Philos. 1994 Dec;19(6):553-69. Unique Identifier : AIDSLINE MED/95256758; Murphy TF; Department of Medical Education, University of Illinois College; of Medicine, Chicago 60612-7309, USA.; Accidental human immunodeficiency virus (HIV) infection of patients in health care settings raises the question about whether patients have a right to expect disclosure of HIV/AIDS diagnoses by their health workers. Although such a right-and the correlative duty to disclose-might appear justified by reason of standard
Going early, going late: the rationality of decisions about suicide in AIDS.: J Med Philos. 1994 Dec;19(6):571-94. Unique Identifier : AIDSLINE MED/95256759; Battin MP; Department of Philosophy, University of Utah, Salt Lake City; 84112, USA.; Where assistance in suicide is readily available to those dying of AIDS, as in the west coast gay communities of the United States and in the Netherlands , we must examine the different roles of physicians and friends (including lovers, spouses,
HIV preventive vaccine research: selected ethical issues.: J Med Philos. 1994 Dec;19(6):595-612. Unique Identifier : AIDSLINE MED/95256760; Grady C; Clinical Therapeutics Laboratory, National Institute of Nursing; Research, National Institute of Health, Bethesda, MD 20892, USA.; This paper explores three selected issues which present ethical challenges unique to the development and testing of preventive HIV vaccines. The issues are: when to move forward with large scale efficacy testing of vaccines, how to incorporate behavioral interventions into the study of vaccine efficacy, and how to pla
Neuropsychiatric aspects of HIV infection [editorial]: J Neurol Neurosurg Psychiatry. 1995 Apr;58(4):399-402. Unique Identifier : AIDSLINE MED/95256851; Everall IP
Pharmacokinetics of all-trans-retinoic acid administered on an intermittent schedule.: J Clin Oncol. 1995 May;13(5):1238-41. Unique Identifier : AIDSLINE MED/95256948; Adamson PC; Bailey J; Pluda J; Poplack DG; Bauza S; Murphy RF; Yarchoan R; Balis FM; Pediatric Branch, National Cancer Institute, Bethesda, MD 20892,; USA.; PURPOSE: Administration of all-trans-retinoic acid (ATRA) on a continuous daily schedule results in a rapid and sustained decrease in plasma drug concentrations. This pharmacokinetic study was performed to determine if administration of ATRA on an intermittent schedule could overcome the rapid decrease in plasma drug
Sustained helping without obligation: motivation, longevity of service, and perceived attitude change among AIDS volunteers.: J Pers Soc Psychol. 1995 Apr;68(4):671-86. Unique Identifier : AIDSLINE MED/95257099; Omoto AM; Snyder M; Department of Psychology, University of Kansas, Lawrence 66045,; USA.; A conceptual framework that identifies psychological and behavioral features associated with antecedents, experiences, and consequences of volunteerism is presented, and an inventory that measures 5 specific motivations for AIDS volunteerism is developed and cross-validated. Then a field study of 116 AIDS volunteers i
Dementia-related behaviors in Alzheimer's disease and AIDS.: J Psychosoc Nurs Ment Health Serv. 1995 Jan;33(1):35-9. Unique Identifier : AIDSLINE MED/95257208; Harvath TA; Patsdaughter CA; Bumbalo JA; McCann MK; School of Nursing, University of Wisconsin-Milwaukee 53201, USA.; In both Alzheimer s disease (AD) and AIDS, family members vary in their perceptions of the individual s ability to control his or her cognitive or behavioral functioning. Family members who believe that the behaviors are unintentional generally experience less distress than do family members who believe that the indiv
Salmonella typhi chorioamnionitis in a human immunodeficiency virus-infected pregnant woman. A case report.: J Reprod Med. 1995 Feb;40(2):157-9. Unique Identifier : AIDSLINE MED/95257275; Hedriana HL; Mitchell JL; Williams SB; Department of Obstetrics and Gynecology, Columbia University; College of Physicians and Surgeons, Harlem Hospital Center, New; York, New York, USA.; Opportunistic prenatal infection is a recognized problem in human immunodeficiency virus (HIV)-infected women from inner city communities. We report a case of intrapartum Salmonella typhi infection and discuss the possible route of infection. An HIV-infected pregnant woman was admitted for fever and ruptured membranes
Change in the epidemiology of Reiter's syndrome (reactive arthritis) in the post-AIDS era? An analysis of cases appearing in the Greek Army.: J Rheumatol. 1995 Feb;22(2):252-4. Unique Identifier : AIDSLINE MED/95257293; Iliopoulos A; Karras D; Ioakimidis D; Arvanitis A; Tsamis N; Iakovou I; Anagnostopoulos I; Giannikos N; Department of Rheumatology, 401 General Army Hospital of Athens,; Greece.; OBJECTIVE. During the last 5 years we observed a significant decrease in the incidence of newly established cases of Reiter s syndrome (reactive arthritis) in Greek Army personnel. Our study was initiated to validate this observation and to evaluate a possible change in the prevalence of Reiter s syndrome (RS) associa
Coexistence of human immunodeficiency virus infection and systemic lupus erythematosus.: J Rheumatol. 1995 Feb;22(2):347-50. Unique Identifier : AIDSLINE MED/95257309; Molina JF; Citera G; Rosler D; Cuellar ML; Molina J; Felipe O; Espinoza LR; Department of Medicine, Louisiana State University Medical Center; (LSUMC), New Orleans 70112-2822, USA.; A variety of rheumatic disorders has been reported during the course of human immunodeficiency virus (HIV) infection; however, its association with systemic lupus erythematosus (SLE) is extremely rare. The effect of HIV infection on CD4 lymphocytes may ameliorate SLE activity and spur remission. We observed 2 patients
Polyarteritis nodosa-like vasculitis in human immunodeficiency virus infection.: J Rheumatol. 1995 Feb;22(2):351-5. Unique Identifier : AIDSLINE MED/95257310; Libman BS; Quismorio FP Jr; Stimmler MM; Division of Rheumatology and Immunology, University of Southern; California School of Medicine, Los Angeles 90033, USA.; Human immunodeficiency virus (HIV) infection can present with musculoskeletal syndromes including systemic vasculitis. We describe vasculitis resembling polyarteritis nodosa (PAN) in 2 HIV-infected individuals and review reported cases to emphasize clinical features. Our patients presented with digital gangrene and ha
Knowledge, attitude and practice towards AIDS among civil servants in Nigeria.: J R Soc Health. 1995 Feb;115(1):19-22. Unique Identifier : AIDSLINE MED/95257323; Okojie OH; Ogbeide O; Nwulia A; Department of Community Health, Uniben.; A study about knowledge, attitude and practice (KAP) towards AIDS was carried out amongst 340 randomly selected workers in Benin City in Nigeria using self-administered questionnaires. Three hundred and thirty (97.1%) of the workers were aware o
Knowledge and attitudes towards AIDS among primary health care physicians in the Asir Region, Saudi Arabia.: J R Soc Health. 1995 Feb;115(1):23-5. Unique Identifier : AIDSLINE MED/95257324; Mahfouz AA; Alakija W; al-Khozayem AA; al-Erian RA; Department of Family and Community Medicine, College of Medicine,; King Saud University, Abha Branch, Saudi Arabia.; STUDY OBJECTIVES: To assess the knowledge and attitudes towards AIDS among practicing physicians in the Asir Region, Saudi Arabia . DESIGN AND PARTICIPANTS: A survey was carried out among primary health care (PHC) physicians working
Expedient method for the solid-phase synthesis of aspartic acid protease inhibitors directed toward the generation of libraries.: J Med Chem. 1995 Apr 28;38(9):1427-30. Unique Identifier : AIDSLINE MED/95257347; Kick EK; Ellman JA; Department of Chemistry, University of California, Berkeley; 94720, USA.
A geometry-based suite of molecular docking processes.: J Mol Biol. 1995 Apr 28;248(2):459-77. Unique Identifier : AIDSLINE MED/95257402; Fischer D; Lin SL; Wolfson HL; Nussinov R; Computer Science Department, School of Mathematical Sciences, Tel; Aviv University, Israel.; We have developed a geometry-based suite of processes for molecular docking. The suite consists of a molecular surface representation, a docking algorithm, and a surface inter-penetration and contact filter. The surface representation is composed of a sparse set of critical points (with their associated normals) posit
[Clinical usefulness of polyamino acid particle agglutination test for detection of anti-HTLV-I antibody]: Rinsho Byori. 1995 Apr;43(4):397-401. Unique Identifier : AIDSLINE MED/95257476; Nishimura Y; Yoshiki K; Nakamitsu M; Fukuyoshi Y; Yamaguchi K; Takatsuki K; Imamura Y; Kusumoto Y; Blood Transfusion Service, Kumamoto University School of; Medicine.; A new artificial carrier particle agglutination test using polyamino acid (polyamino PA) was developed for anti HTLV-I assay. We carried out the comparative study on anti-HTLV-I among polyamino PA, gelatin PA, EIA and WB methods. All of 76 ATL, 20 HAM/TSP, 53 patients with uveitis and 50 HTLV-I carriers were seroposit
Production of a factor inhibiting tumor-cell migration in patients with gastric and breast cancer.: Jpn J Med Sci Biol. 1994 Oct-Dec;47(5-6):265-80. Unique Identifier : AIDSLINE MED/95257503; Raichev IT; Borissova R; Department of Pathology, Pleven Medical University, Bulgaria.; Production of a factor with a biological activity to inhibit the in vitro tumor-cell migration (TCM) from peripheral blood E rosette-forming cells (ERFC), CD4+ and CD8+ T cells in patients with gastric and breast carcinoma was investigated. The cells were stimulated for 2 or 24 hr with allogeneic gastric or breast can
[Anti-HIV therapy (1987-1994): from nothing to confusion]: Med Clin (Barc). 1995 Apr 1;104(12):463-7. Unique Identifier : AIDSLINE MED/95257642; Lissen E; Grupo de Estudio de la Hepatitis Virica y Sida, Hospital; Universitario Virgen del Rocio, Sevilla.
Research into topical microbicides against STDs [news]: Lancet. 1995 May 13;345(8959):1231. Unique Identifier : AIDSLINE MED/95257676; Rowe PM
Transmission of HIV in women [letter; comment]: Lancet. 1995 May 13;345(8959):1241-2. Unique Identifier : AIDSLINE MED/95257693; Stewart GT
Uveitis associated with post-transfusional human T-lymphotropic virus type 1 [letter]: Lancet. 1995 May 13;345(8959):1246-7. Unique Identifier : AIDSLINE MED/95257704; Brezin AP; Gout O; Gessain A; LeHoang P
CD4 similarity to proteins of infectious agents in AIDS and their role in autoimmunity.: Med Hypotheses. 1994 Dec;43(6):361-71. Unique Identifier : AIDSLINE MED/95257802; Root-Bernstein RS; Dewitt SH; Department of Physiology, Michigan State University, East Lansing; 48824, USA.; Lymphocytotoxic autoimmunity (LA) is ubiquitous in AIDS. Its causes are unknown. We report that significant amino acid sequence similarities exist between the proteins of infectious organisms associated with AIDS and the CD4 protein of T-helper lymphocytes. These included: HIV, cytomeg
Molecular mimicry in the pathogenesis of AIDS: the HIV/MHC/mycoplasma triangle.: Med Hypotheses. 1994 Dec;43(6):388-96. Unique Identifier : AIDSLINE MED/95257805; Bisset LR; Department of Internal Medicine, University Hospital, Zurich,; Switzerland.; The immune defects characterizing infection with the human immunodeficiency virus (HIV) and culminating in the acquired immune deficiency syndrome (AIDS) are the result of a multifactorial disease process, components of which are the occurrence of autoimmune phenomena and opportunistic infection. In this discussion, t
Tonsils may show AIDS progression [news]: Minn Med. 1995 Mar;78(3):54. Unique Identifier : AIDSLINE MED/95257875
[Bone involvement of the jaws in AIDS-related Kaposi's sarcoma]: Minerva Stomatol. 1994 Nov;43(11):521-4. Unique Identifier : AIDSLINE MED/95257880; Righi P; Pierleoni L; Ficarra G; Facolta di Medicina e Chirurgia, Universita degli Studi,; Firenze.; The authors report on five patients with jaw bone involvement of Kaposi s sarcoma. In this study clinical, radiographic and histopathological aspects are described.
Human retroviruses and demyelinating diseases.: Neurol Clin. 1995 Feb;13(1):75-97. Unique Identifier : AIDSLINE MED/95257902; Greenberg SJ; Department of Neurology, Roswell Park Cancer Institute, Buffalo,; NY 14263, USA.; The consequences of human retroviral infections have had an unprecedented impact on the medical, scientific, and social institutions of the last two decades of this century. The nervous system as an end target organ figures prominently in the constellation of diseases associated with HTLV and HIV infection and numerou
Youth risk behavior surveillance--United States, 1993.: MMWR CDC Surveill Summ. 1995 Mar 24;44(1):1-56. Unique Identifier : AIDSLINE MED/95257909; Kann L; Warren CW; Harris WA; Collins JL; Douglas KA; Collins ME; Williams BI; Ross JG; Kolbe LJ; PROBLEM/CONDITION: Priority health risk behaviors that contribute to the leading causes of mortality, morbidity, and social problems among youth and adults often are established during youth, extend into adulthood, and are interrelated. REPORTING PERIOD: February through May 1993. DESCRIPTION OF SYSTEM: The Youth Risk
Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA.: Mol Cell Biol. 1995 May;15(5):2359-66. Unique Identifier : AIDSLINE MED/95257915; Talley AK; Dewhurst S; Perry SW; Dollard SC; Gummuluru S; Fine SM; New D; Epstein LG; Gendelman HE; Gelbard HA; Department of Neurology (Child Neurology Division), University of; Rochester Medical Center, New York 14642, USA.; Tumor necrosis factor alpha (TNF-alpha) is a candidate human immunodeficiency virus type 1-induced neurotoxin that contributes to the pathogenesis of AIDS dementia complex. We report here on the effects of exogenous TNF-alpha on SK-N-MC human neuroblastoma cells differentiated to a
Genetic selection for balanced retroviral splicing: novel regulation involving the second step can be mediated by transitions in the polypyrimidine tract.: Mol Cell Biol. 1995 May;15(5):2663-71. Unique Identifier : AIDSLINE MED/95257947; Bouck J; Fu XD; Skalka AM; Katz RA; Institute for Cancer Research, Fox Chase Cancer Center,; Philadelphia, Pennsylvania 19111, USA.; Incomplete splicing is essential for retroviral replication; and in simple retroviruses, splicing regulation appears to occur entirely in cis. Our previous studies, using avian sarcoma virus, indicated that weak splicing signals allow transcripts to escape the splicing pathway. We also isolated a series of avian sarco
Inducible nuclear expression of newly synthesized I kappa B alpha negatively regulates DNA-binding and transcriptional activities of NF-kappa B.: Mol Cell Biol. 1995 May;15(5):2689-96. Unique Identifier : AIDSLINE MED/95257950; Arenzana-Seisdedos F; Thompson J; Rodriguez MS; Bachelerie F; Thomas D; Hay RT; School of Biological and Medical Sciences, University of St.; Andrews, Scotland.; The transcription factor NF-kappa B is exploited by many viruses, including the human immunodeficiency virus, for expression of viral genes, but its primary role appears to be in the rapid induction of cellular genes during immune and inflammatory responses. The inhibitor protein I kappa B alpha maintains NF-kappa B i
Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation.: Mol Cell Biol. 1995 May;15(5):2809-18. Unique Identifier : AIDSLINE MED/95257963; Brockman JA; Scherer DC; McKinsey TA; Hall SM; Qi X; Lee WY; Ballard DW; Howard Hughes Medical Institute, Vanderbilt University School of; Medicine, Nashville, Tennessee 37232-0295, USA.; The eukaryotic transcription factor NF-kappa B plays a central role in the induced expression of human immunodeficiency virus type 1 and in many aspects of the genetic program mediating normal T-cell activation and growth. The nuclear activity of NF-kappa B is tightly regulated from the cytoplasmic compartment by an i
HIV-1 rsgp41 depends on calcium for binding of human c1q but not for binding of gp120.: Mol Immunol. 1995 Apr;32(5):371-4. Unique Identifier : AIDSLINE MED/95257979; Stoiber H; Ebenbichler CF; Thielens NM; Arlaud GJ; Dierich MP; Institut fur Hygiene, Innsbruck, Austria.; Human immunodeficiency virus type 1 activates the complement cascade via the classical pathway by direct binding of C1q through specific sites in the TM surface protein, gp41. In this paper we investigated the divalent cation dependence of the interaction between HIV-1 gp41 and C1q or gp120. A solid phase radioimmunoa
Disseminated cryptococcosis in a patient with AIDS.: Mycoses. 1994 Jul-Aug;37(7-8):275-9. Unique Identifier : AIDSLINE MED/95258069; Reblin T; Meyer A; Albrecht H; Greten H; Medizinische Kernklinik und Poliklinik, Universitatskrankenhaus; Eppendorf, Hamburg, Germany.; We report the case of a 31-year-old AIDS patient who had generalized cryptococcal disease with involvement of the lungs, bone marrow, gastrointestinal tract and skin as well as chorioretinitis which may have been due also to Cryptococcus neoformans infection. Initially there was no involvement of the central nervous s
Clinical outcomes after transfusion-associated hepatitis C [see comments]: N Engl J Med. 1995 Jun 1;332(22):1463-6. Unique Identifier : AIDSLINE MED/95258093; Tong MJ; el-Farra NS; Reikes AR; Co RL; Liver Center, Huntington Memorial Hospital, Pasadena, CA 91105,; USA.; BACKGROUND. The extent of serious complications in people who have acquired chronic hepatitis C infection after a blood transfusion is unclear. METHODS. We studied 131 patients with chronic post-transfusion hepatitis C who were referred to our center between February 1980 and June 1994. Eighty-two other patients were
Images in clinical medicine. Tension pneumopericardium.: N Engl J Med. 1995 Jun 1;332(22):1481. Unique Identifier : AIDSLINE MED/95258096; Smith LG; Naqvi T; Mount Sinai Medical Center, New York, NY 10029, USA.
Antifungal properties of essential oils and their main components upon Cryptococcus neoformans.: Mycopathologia. 1994 Dec;128(3):151-3. Unique Identifier : AIDSLINE MED/95258148; Viollon C; Chaumont JP; Laboratory of Botany, Faculty of Medicine and Pharmacy,; Besancon, France.; Cryptococcus neoformans opportunistic fungus met in the last phasis of AIDS is inhibited in vitro by several essential oils on natural volatile compounds. The minimal inhibitory concentration may reach 100 microliters/l and minimal fungicidal concentration 200 microliters/l with Palmarosa or Cinnamon oils. Among pheno
Human immunodeficiency virus infection and fitness to fly [see comments]: N Z Med J. 1995 Apr 12;108(997):131-2. Unique Identifier : AIDSLINE MED/95258247; Delany S; Department of Medicine, Wellington School of Medicine.
A law for all.: Occup Health Saf. 1995 Mar;64(3):65-6. Unique Identifier : AIDSLINE MED/95258267; Crane WA; Crown Consulting Firm, Inc., of Warsaw, Ind.
Comparative analysis of cleavage rates after systematic permutation of the NUX consensus target motif for hammerhead ribozymes.: Nucleic Acids Res. 1995 Apr 11;23(7):1192-6. Unique Identifier : AIDSLINE MED/95258328; Zoumadakis M; Tabler M; Institute of Molecular Biology and Biotechnology, Foundation for; Research and Technology-Hellas, Crete, Greece.; A trans-cleaving asymmetric hammerhead ribozyme directed against an AUC decreases target motif within an RNA specific for human immunodeficiency virus type 1 (HIV-1) was generated. The AUC decreases motif of the target RNA was permutated in order to generate all 12 variants of an NUX decreases consensus target motif,
Use of primary caretakers as proxies to measure the health care needs of patients with AIDS.: Public Health Nurs. 1995 Apr;12(2):109-16. Unique Identifier : AIDSLINE MED/95258434; Berk RA; School of Nursing, Johns Hopkins University, Baltimore, Maryland,; USA.; This study evaluated the validity of patient-proxy responses to the Healthcare Needs Scale for Patients with HIV/AIDS. This scale measures environmental and psychosocial support, financial resources, health behaviors, social support, and health management. A sample of 35 patients with HIV/AIDS and their primary careta
A description of the gender differences in risk behaviors in young adults with genital herpes.: Public Health Nurs. 1995 Apr;12(2):99-108. Unique Identifier : AIDSLINE MED/95258443; Swanson JM; Dibble SL; Trocki K; Department of Nursing, Samuel Merritt College, Oakland,; California 94609, USA.; The purpose of this paper is to describe gender differences in risk behaviors--substance use and sexual behavior--in young adults with genital herpes . Two-hundred fifty-two young adults with genital herpes were recruited into the study via newspaper advertisements in a West Coas
Prevention of HIV infection in drug abusers: a cost analysis.: Prev Med. 1995 Jan;24(1):3-8. Unique Identifier : AIDSLINE MED/95258471; Gorsky RD; MacGowan RJ; Swanson NM; DelGado BP; Department of Health Management and Policy, University of New; Hampshire, Durham 03824, USA.; BACKGROUND. Counseling and testing for HIV infection is performed at many sites, including drug treatment centers. The actual cost of providing HIV counseling and testing at drug treatment sites, based upon empirical data collection, has not been reported. The average lifetime medical cost for an HIV-infected individu
The effects of multiple UV exposures on HIV-LTR expression.: Photochem Photobiol. 1995 Apr;61(4):378-82. Unique Identifier : AIDSLINE MED/95258556; Schreck S; Panozzo J; Milton J; Libertin CR; Woloschak GE; Argonne National Laboratory, Center for Mechanistic Biology and; Biotechnology, IL 60439-4833, USA.; Previous studies have shown that cellular stress agents such as UV radiation induce transcription from the long terminal repeat (LTR) of the human immunodeficiency virus (HIV). Using HeLa cells stably transfected with the HIV-LTR sequence, which transcriptionally drives the chloramphenicol acetyl transferase (CAT) rep
The reluctance of house staff to perform mouth-to-mouth resuscitation in the inpatient setting: what are the considerations?: Resuscitation. 1994 Dec;28(3):185-93. Unique Identifier : AIDSLINE MED/95258663; Brenner B; Stark B; Kauffman J; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles,; CA, USA.; OBJECTIVE: Medical house staff are required to perform cardiopulmonary resuscitation (CPR) as part of their job responsibilities. Previously it has been shown that house staff are reluctant to perform mouth-to-mouth resuscitation (MMR) in an out of hospital setting. Therefore, whether reluctance to perform MMR extends
[Osteoarticular tuberculosis. Diagnostic contribution of local sampling (see comments)]: Rev Med Interne. 1995;16(3):191-4. Unique Identifier : AIDSLINE MED/95258705; Lemaitre F; Damade R; Pouchot J; Barge J; Boussougant Y; Vinceneux P; Service de medecine interne V, hopital Louis-Mourier, Colombes,; France.; Bone and joint tuberculosis have recently gained a renewal of interest, especially with the spread of HIV infection which may increase its frequency. Bone and joint locations of tuberculosis are pauci-bacillary often requiring local sampling in order to confirm the diagnosis and to initiate early therapy. From 1983 to
End-of-life family decision-making from disclosure of HIV through bereavement.: Sch Inq Nurs Pract. 1994 Winter;8(4):321-52; discussion 353-9. Unique Identifier : AIDSLINE MED/95258717; Stewart BM; Lienhard School of Nursing, Pace University, USA.; End-of-life decision-making is conceptualized as the foreground against the background of a family, transitional model of illness with the human immunodeficiency virus (HIV). Both foreground and background represent new knowledge and theory development emerging from six research studies over a 7-year period. The resea
[Control of friends and relatives (contact tracing) has been neglected in the case of HIV infections. Results of a 'look-back' study carried out in Switzerland]: Rev Med Suisse Romande. 1995 Apr;115(4):337-40. Unique Identifier : AIDSLINE MED/95258735; April K; Thevoz F; SIDA Information Suisse, Zurich.
[Focus on the role of ventilation and ultraviolet rays in preventing nosocomial transmission of tuberculosis in health care facilities. Groupe de travail sur la prevention de la transmission nosocomiale de la tuberculose (Direction Generale de la Sante)]: Rev Pneumol Clin. 1995;51(1):13-21. Unique Identifier : AIDSLINE MED/95258740; Desenclos JC; Abiteboul D; Bouvet E; Brucker G; Demeulemester R; Haury B; Hure P; Leprince A; Macrez A; Mayaud C; et al; Reseau National de Sante publique, Saint-Maurice.; Recent episodes of nosocomial tuberculosis, sometimes due to multiresistant strains, in HIV infected patients in the USA has led to the need for new prevention measures against the transmission of Mycobacterium tuberculosis in health care facilities. Tuberculosis is transmitted in Pflugge droplets generated when conta
[Clinical value of a polymerase chain reaction on cytomegalovirus DNA in cerebrospinal fluid in HIV patients with neurological symptoms]: Schweiz Med Wochenschr. 1995 Apr 29;125(17):846-53. Unique Identifier : AIDSLINE MED/95258776; Roedel C; Grob R; Ruef C; Department Innere Medizin, Universitatsspital Zurich.; The value of the PCR for CMV in the CSF was evaluated. 23 samples from 20 patients were examined for CMV DNA, of which 11 were positive and 12 were negative for CMV. The clinical spectrum of the patients with positive samples included encephalitis, encephalitis,
Residual risk of transmission of HIV through blood transfusion in South Africa.: S Afr Med J. 1994 Mar;84(3):142-4. Unique Identifier : AIDSLINE MED/95258850; Sitas F; Fleming AF; Morris J; Department of Tropical Diseases, School of Pathology of the South; African Institute for Medical Research, Johannesburg.; Despite the ongoing review of donor recruitment criteria by local blood transfusion services and the development of highly sensitive and specific testing for the presence of antibodies to HIV in blood and blood products, there remains a residue of HIV in donated blood. This is because of donors who are in the window
Morality and AIDS [letter; comment]: S Afr Med J. 1994 Mar;84(3):170. Unique Identifier : AIDSLINE MED/95258861; Jaffe A
Neonatal HIV infection [letter]: S Afr Med J. 1994 Mar;84(3):180. Unique Identifier : AIDSLINE MED/95258870; Baker EF; Steele AD; Williams MM; Bezuidenhout S; Lecatsas G
Treatment of syphilis in HIV-infected individuals--more questions than answers?: S Afr Med J. 1994 Jun;84(6):320-1. Unique Identifier : AIDSLINE MED/95258877; Schon B; Maartens G; Department of Pharmacology, University of Cape Town.
Seroprevalence of HTLV-I in Natal/KwaZulu [letter]: S Afr Med J. 1994 Jun;84(6):368. Unique Identifier : AIDSLINE MED/95258907; Bhigjee AI; Thaler D; Madurai S; Gouws E; Bill PL
Modelling epidemics with variable contact rates.: Theor Popul Biol. 1995 Apr;47(2):129-79. Unique Identifier : AIDSLINE MED/95258948; Greenhalgh D; Das R; Department of Statistics and Modelling Science, University of; Strathclyde, Glasgow, Scotland.; In this paper we look at models for epidemics where the contact rate is a monotone increasing function of the population density. The background death rate also depends on the population density. We first examine the case of a constant contact rate (motivated by AIDS) and here obtain some global stability results. We
Epidemiology of haemophilia in Greece: an overview.: Thromb Haemost. 1994 Dec;72(6):808-13. Unique Identifier : AIDSLINE MED/95258954; Koumbarelis E; Rosendaal FR; Gialeraki A; Karafoulidou A; Noteboom WM; Loizou C; Panayotopoulou C; Markakis C; Mandalaki T; Second Regional Blood Transfusion Centre, Laikon General; Hospital, Athens, Greece.; Demographic data of the Greek haemophilia A and B population for the period 1972-1993 were analyzed. Prevalence at birth including known not-registered patients was calculated at 23.1 per 100,000 male births. However, the observed prevalence in 1993 was only 61% of the expected. Since 1975 the proportion of mild cases
Hypericin as an inactivator of infectious viruses in blood components [see comments]: Transfusion. 1995 May;35(5):392-400. Unique Identifier : AIDSLINE MED/95259149; Lavie G; Mazur Y; Lavie D; Prince AM; Pascual D; Liebes L; Levin B; Meruelo D; Department of Pathology, New York University Medical Center, New; York, USA.; BACKGROUND: Hypericin is a potent virucidal agent with activity against a broad range of enveloped viruses and retroviruses. The effective virucidal activity emanates from a combination of photodynamic and lipophilic properties. Hypericin binds cell membranes (and, by inference, virus membranes) and crosslinks virus c
Virus inactivation in red cell concentrates by photosensitization with phthalocyanines: protection of red cells but not of vesicular stomatitis virus with a water-soluble analogue of vitamin E [see comments]: Transfusion. 1995 May;35(5):401-6. Unique Identifier : AIDSLINE MED/95259150; Ben-Hur E; Rywkin S; Rosenthal I; Geacintov NE; Horowitz B; Virus Inactivation Laboratory, Lindsley F. Kimball Research; Institute, New York Blood Center, New York, USA.; BACKGROUND: Photodynamic treatment of red cells (RBCs) with phthalocyanines and red light inactivates lipid-enveloped viruses, such as vesicular stomatitis virus (VSV) and human immunodeficiency virus. To protect RBCs from photodynamic damage, type I free radical quenchers, such as mannitol, which did not affect virus
Home blood transfusion therapy: a home health agency's 5-year experience [letter]: Transfusion. 1995 May;35(5):453. Unique Identifier : AIDSLINE MED/95259158; Thompson HW; McKelvey J
[Risk factors of listeriosis in Denmark 1989-1990]: Ugeskr Laeger. 1995 Mar 20;157(12):1674-8. Unique Identifier : AIDSLINE MED/95259168; Jensen A; Gerner-Smidt P; Frederiksen W; Klinisk mikrobiologisk afdeling, Statens Seruminstitut,; Kobenhaven.; Risk factors for listeriosis are foods and underlying diseases. A case-control-study of listeriosis patients dietary habits showed that unpasteurized milk was a risk food for sporadic listeriosis. A blue-mould cheese was significantly more often eaten by patients ill with an epidemic phage type. Leukaemia, AIDS and r
There is nothing permanent except change. The emergence of new virus diseases.: Vet Microbiol. 1995 Feb;43(2-3):103-22. Unique Identifier : AIDSLINE MED/95259293; Truyen U; Parrish CR; Harder TC; Kaaden OR; Institute for Medical Microbiology, Infectious and Epidemic; Diseases, Ludwig Maximilians University, Munich, Germany.; The sudden appearance of apparently new viruses with pathogenic potential is of fundamental importance in medical microbiology and a constant threat to humans and animals. The emergence of a new pathogen is not an isolated event, as for instance the frequent appearance of new influenza virus strains demonstrates. Ofte
[Basic results from studies on AIDS]: Vopr Virusol. 1995 Jan-Feb;40(1):2-4. Unique Identifier : AIDSLINE MED/95259335; Pokrovskii VI; Kraevskii AA; Pokrovskii VV; Uryvaev LV; Matsevich GR; Iurin OG; Reshetnikova LN
[Detection of human immunodeficiency virus (HIV-1) p24 antigen in immune complexes]: Vopr Virusol. 1995 Jan-Feb;40(1):8-12. Unique Identifier : AIDSLINE MED/95259343; Pokrovskii AG; Fediuk NV; Rzhanninova AA; Garaev MM; Enzyme-linked immunosorbent assay (ELISA) test-system for HIV-1 p24 antigen detection in human blood specimens has been developed. Use of complex biotin-streptavidin-horseradish peroxidase conjugate increased the sensitivity of the method to 50 pg/ml. The test system is characterized by 100 percent specificity, wherea
Pattern of arterial aneurysms in acquired immunodeficiency disease.: World J Surg. 1995 Jan-Feb;19(1):127-32. Unique Identifier : AIDSLINE MED/95259351; Marks C; Kuskov S; Department of Cardiothoracic Surgery, Parirenyatwa Hospital,; Borrowdale, Harare, Zimbabwe.; The ever-spreading incidence of infection with the human immunodeficiency virus (HIV) has introduced a spectrum of unusual, subtle, and often life-threatening lesions that can affect almost every organ and tissue in the body. With the introduction of laboratory serologic evidence of HIV infection, the spectrum of indi
Development and selection of T cells: facts and puzzles.: Adv Immunol. 1995;58:87-209. Unique Identifier : AIDSLINE MED/95259592; Kisielow P; von Boehmer H; Basel Institute for Immunology, Switzerland.
AIDS-related Burkitt's lymphoma. Morphologic and immunophenotypic study of biopsy specimens.: Am J Clin Pathol. 1995 May;103(5):561-7. Unique Identifier : AIDSLINE MED/95259662; Carbone A; Gloghini A; Gaidano G; Cilia AM; Bassi P; Polito P; Vaccher E; Saglio G; Tirelli U; Division of Pathology, Istituto Nazionale di Ricovero e Cura a; Carattere Scientifico, Aviano, Italy.; In patients infected with HIV, high-grade B-cell non-Hodgkin s lymphomas (NHL), including the small noncleaved cell (SNCC) category, exhibit pleomorphic features, which makes precise definition difficult. Sixty-nine pathologic specimens with HIV-related systemic lymphomas, including 42 SNCC, 20 immunoblastic lymphomas
Rhodococcus equi--an increasingly recognized opportunistic pathogen. Report of 12 cases and review of 65 cases in the literature.: Am J Clin Pathol. 1995 May;103(5):649-55. Unique Identifier : AIDSLINE MED/95259676; Scott MA; Graham BS; Verrall R; Dixon R; Schaffner W; Tham KT; Department of Pathology, Vanderbilt University Medical Center,; Nashville, Tennessee 37232, USA.; Rhodococcus equi, a gram-positive, weakly acid-fast coccobacillus, initially isolated from horses, is becoming increasingly recognized as an important pathogen for immunosuppressed human hosts since the first human case was reported in 1967. A review of the English medical literature yielded 53 cases. During the last
Detection of circulating antigens of Toxoplasma gondii in human infection.: Am J Trop Med Hyg. 1995 Apr;52(4):336-9. Unique Identifier : AIDSLINE MED/95259738; Hafid J; Tran Manh Sung R; Raberin H; Akono ZY; Pozzetto B; Jana M; Laboratoire de Parasitologie, CHU de Saint Etienne, Hopital Nord,; France.; Seventy-nine serum specimens from pregnant women and 29 from immunocompromised patients (12 from graft recipients and 17 from patients with acquired immunodeficiency syndrome) were classified into three groups according to their serologic status to Toxoplasma gondii as determined by immunofluorescence and an enzyme-li
Induction of adrenal suppression by megestrol acetate in patients with AIDS.: Ann Intern Med. 1995 Jun 1;122(11):843-5. Unique Identifier : AIDSLINE MED/95259939; Leinung MC; Liporace R; Miller CH; Division of Endocrinology and Metabolism A-44, Albany Medical; College, NY 12208, USA.; OBJECTIVE: To investigate the development of secondary adrenal suppression in a patient with the acquired immunodeficiency syndrome (AIDS) who was receiving megestrol acetate. DESIGN AND PATIENTS: Case report of one patient abruptly withdrawn from long-term therapy with megestrol acetate; prospective study of four pat
Early or deferred zidovudine therapy in HIV-infected patients without an AIDS-defining illness [see comments]: Ann Intern Med. 1995 Jun 1;122(11):856-66. Unique Identifier : AIDSLINE MED/95259942; Ioannidis JP; Cappelleri JC; Lau J; Skolnik PR; Melville B; Chalmers TC; Sacks HS; Tufts University School of Medicine, Boston, Massachusetts, USA.; PURPOSE: To do a meta-analysis on the efficacy of early or deferred zidovudine monotherapy in patients with human immunodeficiency virus (HIV) infection but not the acquired immunodeficiency syndrome (AIDS). DATA SOURCES: Articles on zidovudine monotherapy published through May 1994. STUDY SELECTION: Double-blind, ran
Megestrol for AIDS-related anorexia [letter; comment]: Ann Intern Med. 1995 Jun 1;122(11):879; discussion 881. Unique Identifier : AIDSLINE MED/95259946; Hengge UR; Brockmeyer NH; Goos M
Megestrol for AIDS-related anorexia [letter; comment]: Ann Intern Med. 1995 Jun 1;122(11):880. Unique Identifier : AIDSLINE MED/95259948; Hodgson DC; Redelmeier DA
Megestrol for AIDS-related anorexia [letter; comment]: Ann Intern Med. 1995 Jun 1;122(11):880; discussion 881. Unique Identifier : AIDSLINE MED/95259949; Cohen MH
Megestrol for AIDS-related anorexia [letter; comment]: Ann Intern Med. 1995 Jun 1;122(11):880; discussion 881. Unique Identifier : AIDSLINE MED/95259950; Maurer M
Neurologic manifestations of HIV infection [letter; comment]: Ann Intern Med. 1995 Jun 1;122(11):883. Unique Identifier : AIDSLINE MED/95259954; Harindra V
Neurologic manifestations of HIV infection [letter; comment]: Ann Intern Med. 1995 Jun 1;122(11):883-4. Unique Identifier : AIDSLINE MED/95259956; Stricker RB
Neurologic manifestations of HIV infection [letter; comment]: Ann Intern Med. 1995 Jun 1;122(11):884. Unique Identifier : AIDSLINE MED/95259957; Pulido F; Rubio R; Costa JR
Severe megaloblastic anemia complicating pyrimethamine therapy [letter]: Ann Intern Med. 1995 Jun 1;122(11):884-5. Unique Identifier : AIDSLINE MED/95259958; Chute JP; Decker CF; Cotelingam J
Acquired rectovaginal fistula [letter; comment]: Arch Dis Child. 1995 Mar;72(3):275. Unique Identifier : AIDSLINE MED/95260167; Oliver MJ
Pseudomonal rectovaginal abscesses in HIV infection [letter; comment]: Arch Dis Child. 1995 Mar;72(3):275. Unique Identifier : AIDSLINE MED/95260169; Sharland M; Peake J; Davies EG
Rehabilitation in joint and connective tissue diseases. 1. Systemic diseases.: Arch Phys Med Rehabil. 1995 May;76(5 Spec No):S32-40. Unique Identifier : AIDSLINE MED/95260211; Alpiner N; Oh TH; Hinderer SR; Brander VA; Hurley Medical Center, Flint, MI 48503, USA.; This self-directed learning module highlights new advances in this topic area. It is part of the chapter on rehabilitation in joint and connective tissue diseases in the Self-Directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation. This article discusses treatment a
Abdominal surgery in HIV/AIDS patients: indications, operative management, pathology and outcome.: Aust N Z J Surg. 1995 May;65(5):320-6. Unique Identifier : AIDSLINE MED/95260267; Yii MK; Saunder A; Scott DF; Fairfield Hospital, Victoria, Australia.; Despite the increasing number of patients with the human immunodeficiency virus (HIV) infection, surgical experience with these patients remains limited. A retrospective review over a 9 year period (January 1985 to December 1993) was undertaken to determine the indications, operative management, pathologic findings an
Isolation of a previously unidentified polysaccharide (MAR-10) from Hyssop officinalis that exhibits strong activity against human immunodeficiency virus type 1.: Biochem Biophys Res Commun. 1995 May 5;210(1):145-51. Unique Identifier : AIDSLINE MED/95260334; Gollapudi S; Sharma HA; Aggarwal S; Byers LD; Ensley HE; Gupta S; Division of Basic & Clinical Immunology, University of; California, Irvine 92717, USA.; A polysaccharide (MAR-10) was isolated from the aqueous extract of the plant Hyssop officinalis and examined for its activity against HIV-1 (SF strain) in HUT78 T cell line and primary cultures of peripheral blood mononuclear cells. MAR-10, in a concentration-dependent manner, inhibited HIV-1 replication as demonstrat
Pharmacokinetics and tissue distribution in rats of an oligodeoxynucleotide phosphorothioate (GEM 91) developed as a therapeutic agent for human immunodeficiency virus type-1.: Biochem Pharmacol. 1995 Mar 30;49(7):929-39. Unique Identifier : AIDSLINE MED/95260368; Zhang R; Diasio RB; Lu Z; Liu T; Jiang Z; Galbraith WM; Agrawal S; Department of Pharmacology and Toxicology, University of Alabama; at Birmingham 35294, USA.; An antisense oligodeoxynucleotide phosphorothioate, namely gene expression modulator 91 (GEM 91), has been demonstrated to have significant anti-human immunodeficiency virus activity in various tissue culture models. The present study was undertaken to determine the pharmacokinetics and tissue distribution of GEM 91 i
Eosinophil function in health and disease.: Crit Rev Oncol Hematol. 1995 Apr;19(1):47-77. Unique Identifier : AIDSLINE MED/95260437; Silberstein DS; Department of Rheumatology and Immunology, Brigham and Women's; Hospital, Boston, MA, USA.
Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects.: Am J Respir Cell Mol Biol. 1995 May;12(5):477-87. Unique Identifier : AIDSLINE MED/95260502; Ying S; Durham SR; Corrigan CJ; Hamid Q; Kay AB; Department of Allergy and Clinical Immunology, National Heart and; Lung Institute, London, United Kingdom.; We investigated the phenotype of cells expressing messenger RNA encoding interleukin 4 (IL-4), IL-5, IL-2 , and interferon gamma (IFN-gamma) in bronchoalveolar lavage (BAL) and bronchial biopsies (BX) from seven mild atopic asthmatic patients and nine nonasthmatic contr
Peripheral blood CD4 but not CD8 t-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy.: Am J Respir Cell Mol Biol. 1995 May;12(5):567-78. Unique Identifier : AIDSLINE MED/95260512; Corrigan CJ; Hamid Q; North J; Barkans J; Moqbel R; Durham S; Gemou-Engesaeth V; Kay AB; Department of Allergy and Clinical Immunology, National Heart and; Lung Institute, London, United Kingdom.; T-lymphocyte (T-LC)-derived cytokines have been implicated in asthma pathogenesis. Activation of peripheral blood CD4 but not CD8 T-LC and a Th2-type pattern of elevated cytokine mRNA expression in BAL fluid T-LC have been observed in asthmatics, but the principal source (CD4 or CD8 T-LC) of these cytokines is unknown
Two partially overlapping antiviral peptides from the external portion of HIV type 1 glycoprotein 41, adjoining the transmembrane region, affect the glycoprotein 41 fusion domain [letter]: AIDS Res Hum Retroviruses. 1995 Feb;11(2):189-90. Unique Identifier : AIDSLINE MED/95260527; Neurath AR; Lin K; Strick N; Jiang S
A general model for the surface glycoproteins of HIV and other retroviruses.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):191-202. Unique Identifier : AIDSLINE MED/95260528; Gallaher WR; Ball JM; Garry RF; Martin-Amedee AM; Montelaro RC; Department of Microbiology, Immunology, and Parasitology,; Louisiana State University Medical Center, New Orleans 70112,; USA.; A hypothetical model of the surface (SU) glycoproteins of human immunodeficiency virus (HIV) and other retroviruses is proposed. The model is based on repetition of a limited number of sequence motifs conserved within the virus family; similarities in biological, immunological, or genetic properties; as well as the te
Effect of adjuvants on immunogenicity of MN recombinant glycoprotein 120 in guinea pigs.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):203-9. Unique Identifier : AIDSLINE MED/95260529; Powell MF; Eastman DJ; Lim A; Lucas C; Peterson M; Vennari J; Weissburg RP; Wrin T; Kensil CR; Newman MJ; et al; Department of Pharmaceutical Research, Genentech, Inc., South San; Francisco, California 94080, USA.; The immunogenicity of recombinant gp120 from the MN strain of HIV-1, a candidate HIV-1 vaccine, was evaluated in guinea pigs using adjuvant formulations with different physical and chemical properties. The adjuvants tested included Freund s adjuvant (FA), alum, and the novel adjuvant QS-21. These studies demonstrated
HIV type 1 V3 region primer-induced antibody suppression is overcome by administration of C4-V3 peptides as a polyvalent immunogen.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):211-21. Unique Identifier : AIDSLINE MED/95260530; Haynes BF; Moody MA; Heinley CS; Korber B; Millard WA; Scearce RM; Department of Medicine, Duke University School of Medicine,; Durham, North Carolina 27710, USA.; The extreme variability of HIV-1 immunogenic regions has hampered attempts to design immunogens capable of inducing broadly reactive neutralizing anti-HIV antibody responses. We have begun to study the immune responses generated to a polyvalent mixture of HIV envelope gp120 synthetic peptides, and to determine the abi
HIV type 1 protease activation of NF-kappa B within T lymphoid cells.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):223-30. Unique Identifier : AIDSLINE MED/95260531; Zhang D; Zhang N; Wick MM; Byrn RA; Department of Medicine, Harvard Medical School, Boston,; Massachusetts 02215, USA.; NF-kappa B is a nuclear protein of the rel oncogene family capable of enhancing transcription of several cellular genes, including IL-2 and the IL-2 receptor, and viral genes transcribed from the HIV-1 LTR. It has been reported that HIV-1 protease may cleave the NF-kap
Correlation between genetic and biological properties of biologically cloned HIV type 1 viruses representing subtypes A, B, and D.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):239-48. Unique Identifier : AIDSLINE MED/95260533; Zhong P; Peeters M; Janssens W; Fransen K; Heyndrickx L; Vanham G; Willems B; Piot P; van der Groen G; Department of Infection and Immunity, Institute of Tropical; Medicine, Antwerp, Belgium.; The relationship between the genetic variability in the V3 loop and the biological characteristics of 38 biological clones from 5 European and 7 African HIV-1 isolates belonging to 3 different subtypes (subtype A, B, and D) was investigated. Seventeen of 19 clones displaying a syncytium-inducing (SI) capacity had a po
Programmed cell death induced by HIV type 1 antigen stimulation is associated with a decrease in cytotoxic T lymphocyte activity in advanced HIV type 1 infection.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):249-56. Unique Identifier : AIDSLINE MED/95260534; Chia WK; Freedman J; Li X; Salit I; Kardish M; Read SE; Department of Microbiology, University of Toronto, Ontario,; Canada.; The immune competence of peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus-seropositive (HIV+) patients was studied by assessing cytotoxic T lymphocyte (CTL) activity following recall HIV antigen stimulation. Target cells were HLA-A-matched EBV-transformed B cells expressing HIV-1 antigen. I
Ex vivo expansion of HIV type 1-specific cytolytic T cells from HIV type 1-seropositive subjects.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):257-71. Unique Identifier : AIDSLINE MED/95260535; Lieberman J; Fabry JA; Shankar P; Beckett L; Skolnik PR; Department of Medicine, New England Medical Center, Boston,; Massachusetts 02111, USA.; Cytotoxic T lymphocytes that specifically lyse HIV-1-infected cells occur at uncommonly high frequency in the blood of infected individuals. The CTL response is dominated by the recognition of a small number of peptides encoded by HIV-1 structural and regulatory genes. These two facts have enabled us to develop potent
Distribution of SIV in lymph nodes of serially sacrificed rhesus monkeys.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):273-85. Unique Identifier : AIDSLINE MED/95260536; Baskin GB; Martin LN; Murphey-Corb M; Hu FS; Kuebler D; Davison B; Department of Pathology, Tulane Regional Primate Research Center,; Tulane University, Covington, Louisiana 70433, USA.; Rhesus monkeys were inoculated with SIVDeltaB670 and sacrificed 2, 4, 8, and 24 weeks after inoculation or when moribund. Two monkeys predicted to have a rapid disease course and two predicted to have a slower disease course were sacrificed at each time point. Lymph nodes were studied by histopathology, immunohistoche
HIV type 1 intraperitoneal infection of rabbits permits early detection of serum antibodies to Gag, Pol, and Env proteins, neutralizing antibodies, and proviral DNA from peripheral blood mononuclear cells.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):287-96. Unique Identifier : AIDSLINE MED/95260537; Debiaggi M; Bruno R; Carlevari M; Achilli G; Emanuelli B; Cereda PM; Romero E; Filice G; Institute of Microbiology, University of Pavia, Italy.; The aim of this study is the development of an animal model useful for studying HIV-1 pathogenesis, candidate vaccines, and antiviral drugs. Aseptic thioglycolate peritonitis was induced in six rabbits. After 4 days, four rabbits were infected with 1 ml of HIV-1 stock containing 100 times the MID50. Blood samples were
Rabbits transfused with human immunodeficiency virus type 1-infected blood develop immune deficiency with CD4+ lymphocytopenia in the absence of clear evidence for HIV type 1 infection.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):297-306. Unique Identifier : AIDSLINE MED/95260538; Simpson RM; Hubbard BS; Alling DW; Teller R; Fain MA; Bowers FS; Kindt TJ; Laboratory of Immunogenetics, National Institute of Allergy and; Infectious Disease, NIH-Twinbrook II Facility, Rockville,; Maryland 20852, USA.; Rabbits can be infected with human immunodeficiency virus (HIV-1), but no disease signs similar to acquired immunodeficiency syndrome (AIDS) have been reported to date. In our attempt to develop types of HIV-1 more virulent for rabbits, an immunodeficiency characterized by CD4+ lymphocytopenia and opportunistic infect
Highly attenuated HTLV type Ienv poxvirus vaccines induce protection against a cell-associated HTLV type I challenge in rabbits.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):307-13. Unique Identifier : AIDSLINE MED/95260539; Franchini G; Tartaglia J; Markham P; Benson J; Fullen J; Wills M; Arp J; Dekaban G; Paoletti E; Gallo RC; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.; The entire envelope protein of the human T cell leukemia/lymphoma virus type I (HTLV-I)1711, obtained from the DNA of a West African healthy HTLV-I-infected patient, was expressed in the highly attenuated poxvirus vaccine vectors ALVAC and NYVAC. These live recombinant vaccine candidates were used to immunize
HTLV-negative and HTLV type I-positive tropical spastic paraparesis in northeastern Brazil.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):315-8. Unique Identifier : AIDSLINE MED/95260540; Costa CM; Goubau P; Liu HF; Vandamme AM; da Cunha FM; Santos TJ; Desmyter J; Carton H; Department of Neurology, University Hospital, Fortaleza, Ceara,; Brazil.; A type-specific serological survey among 1042 random nonneurological outpatients in two cities in the state of Ceara (northeastern Brazil ) shows a low prevalence of HTLV-I (0.34% in Fortaleza; 0.44% in Crato) and of HTLV-II (0.34% in Fortaleza; 0% in Crato). Among 62 chronic myelop
Serological, virological, and polymerase chain reaction studies of HIV type 1 and HIV type 2 infections in Ghanaian patients with AIDS and AIDS-related complex.: AIDS Res Hum Retroviruses. 1995 Feb;11(2):319-21. Unique Identifier : AIDSLINE MED/95260541; Ayisi NK; Mensah M; Ishikawa K; Sata T; Noguchi Memorial Institute for Medical Research, University of; Ghana, Legon.; We have used a particle agglutination (PA) test, Western blot (WB) test, polymerase chain reaction (PCR) test, and virus isolation to define the human immunodeficiency virus (HIV) status of 17 acquired immunodeficiency syndrome (AIDS), 6 AIDS-related complex (ARC), and 2 asymptomatic Ghanaians. HIV-1 antibodies were m
[Cytomegalovirus colitis in a patient carrying the human immunodeficiency virus: the endoscopic image similar to pseudomembranous colitis]: Rev Esp Enferm Dig. 1995 Mar;87(3):247-9. Unique Identifier : AIDSLINE MED/95260549; Erdozain JC; Lizasoain J; Martin-de-Argila C; Presa M; Munoz F; Servicio de Gastroenterologia, Hospital La Paz, Madrid.; Endoscopically detected ulcers and submucous haemorrhage are common findings related to cytomegalovirus infection. We report a case of cytomegalovirus colitis in a patient seropositive for human immunodeficiency virus. Endoscopic findings showed elevated, white-yellowish, small siz
GDC ethical guidance in relation to HIV and other blood-borne viruses.: Br Dent J. 1995 Apr 22;178(8):315. Unique Identifier : AIDSLINE MED/95260604
The stigmatized patient with AIDS in the intensive care unit: the role of the advanced practice nurse.: AACN Clin Issues Crit Care Nurs. 1994 Nov;5(4):495-500. Unique Identifier : AIDSLINE MED/95260635; Mosier L; As the incidence of HIV infection rises, so will cases of HIV positive intensive care unit admissions. Factors affecting nurses care of these patients include fear of contagion, homophobia, and lack of knowledge. A multidimensional approach must be taken by the advanced practice nurse to decrease stigmatization by ch
HIV screening in healthy volunteers [letter; comment]: Br J Clin Pharmacol. 1995 Feb;39(2):213-4. Unique Identifier : AIDSLINE MED/95260664; Harry JD; Baber N; Posner J
Multiple molluscum contagiosum lesions of the limbus in a patient with HIV infection [letter]: Br J Ophthalmol. 1995 Apr;79(4):393-4. Unique Identifier : AIDSLINE MED/95260790; Merisier H; Cochereau I; Hoang-Xuan T; Toublanc M; Ruggeri C
Age, gender, and other predictors of the wasting syndrome among HIV-1-infected injecting drug users.: Epidemiology. 1995 Mar;6(2):172-7. Unique Identifier : AIDSLINE MED/95260904; Sorkin JD; Bolton PA; Greenblatt J; Sithisarankul P; Vlahov D; Graham NM; Epidemiology, Demography, and Biometry Program, National; Institute on Aging, National Institutes of Health, Bethesda, MD; 20892, USA.; We conducted a study to identify predictors of the wasting syndrome among human immunodeficiency virus 1 (HIV-1)-seropositive injecting drug users. We enrolled 113 cases (defined as an unexplained loss of > 10% baseline weight) and 226 controls (defined as
AIDS, tuberculosis, and the health care worker.: Clin Infect Dis. 1995 Feb;20(2):232-42. Unique Identifier : AIDSLINE MED/95260920; Sepkowitz KA; Infectious Disease Service, Memorial Sloan-Kettering Cancer; Center, New York Hospital-Cornell Medical Center, New York 10021,; USA.; The combination of tuberculosis and infection with the human immunodeficiency virus type-1 (HIV-1) poses an increased hazard to health care workers. In this AIDS Commentary, Dr. Kent Sepkowitz of Memorial Sloan-Kettering Cancer Center and New York Hospital-Cornell Medical Center reviews the current state of our knowle
Dapsone/pyrimethamine may prevent mycobacterial disease in immunosuppressed patients infected with the human immunodeficiency virus.: Clin Infect Dis. 1995 Feb;20(2):244-9. Unique Identifier : AIDSLINE MED/95260922; Opravil M; Pechere M; Lazzarin A; Heald A; Ruttimann S; Iten A; Furrer H; Oertle D; Praz G; Vuitton DA; et al; University Hospital of Zurich, Switzerland.; Dapsone exhibits activity against Mycobacterium tuberculosis and Mycobacterium avium complex (MAC) in vitro. We retrospectively examined the incidence of mycobacterial diseases within a randomized prospective trial of prophylaxis for Pneumocystis carinii pneumonia and toxoplasmosis. Of 501 participants who had not pre
Thalidomide as treatment of refractory aphthous ulceration related to human immunodeficiency virus infection.: Clin Infect Dis. 1995 Feb;20(2):250-4. Unique Identifier : AIDSLINE MED/95260923; Paterson DL; Georghiou PR; Allworth AM; Kemp RJ; Infectious Diseases Unit, Royal Brisbane Hospital, Herston,; Queensland, Australia.; In recent years, thalidomide has been used for the treatment of a variety of ulcerative and immunologic conditions. Several previous reports have suggested that thalidomide therapy is beneficial for patients with aphthous ulceration related to human immunodeficiency virus (HIV) infection. We describe the use of thalid
Amphotericin B as primary therapy for cryptococcosis in patients with AIDS: reliability of relatively high doses administered over a relatively short period [see comments]: Clin Infect Dis. 1995 Feb;20(2):263-6. Unique Identifier : AIDSLINE MED/95260926; de Lalla F; Pellizzer G; Vaglia A; Manfrin V; Franzetti M; Fabris P; Stecca C; Department of Infectious Diseases, San Bortolo Hospital, Vicenza,; Italy.; Thirty-one consecutive AIDS patients with cryptococcal disease were enrolled in a study of the efficacy and safety of short-course primary treatment with a relatively high dose of amphotericin B (1 mg/[kg.d] for 14 days); 26 patients also received flucytosine (100-150 mg/[kg.d], given either intravenously or orally).
The practice of infectious diseases in the 1990s: the Canadian experience.: Clin Infect Dis. 1995 Feb;20(2):291-5. Unique Identifier : AIDSLINE MED/95260931; Schlech WF 3rd; Department of Medicine, Dalhousie University, Halifax, Nova; Scotia, Canada.; A survey of the members of the Canadian Infectious Disease Society was carried out to determine the content of an infectious diseases consultative practice in the 1990s. Respondents were asked to identify all new inpatient, outpatient, and telephone consultations during a 1-week period in 1990. Consultations were cate
Human immunodeficiency virus infection and porphyria cutanea tarda: coexistence of risk factors or causative association?: Clin Infect Dis. 1995 Feb;20(2):348-51. Unique Identifier : AIDSLINE MED/95260940; McAlister F; McClean K; Hamilton PG; Houston S; Department of Medicine, University of Alberta Hospital, Edmonton,; Canada.; Several recent reports have described an association between human immunodeficiency virus (HIV) infection and porphyria cutanea tarda (PCT). We describe two HIV-infected patients who developed PCT and review 29 other reported cases of coexistent PCT and infection due to HIV. Recognized porphyrinogenic factors were ide
Prognostic value of combined response markers among human immunodeficiency virus-infected persons: possible aid in the decision to change zidovudine monotherapy.: Clin Infect Dis. 1995 Feb;20(2):352-62. Unique Identifier : AIDSLINE MED/95260941; Graham NM; Park LP; Piantadosi S; Phair JP; Mellors J; Fahey JL; Saah AJ; Department of Epidemiology, Johns Hopkins Medical Institutions,; Baltimore, Maryland 21205, USA.; To clarify useful clinical parameters for determining the need for changes in antiretroviral regimens, 586 persons who were seropositive for the human immunodeficiency virus (HIV) and who had intermediate-stage HIV disease underwent follow-up semiannually for a median of 3.1 years after zidovudine monotherapy was inst
Outcome for hospitalized patients with fever and neutropenia who are infected with the human immunodeficiency virus.: Clin Infect Dis. 1995 Feb;20(2):363-71. Unique Identifier : AIDSLINE MED/95260942; Hambleton J; Aragon T; Modin G; Northfelt DW; Sande MA; Department of Medicine, University of California, San Francisco; 94143, USA.; We conducted a retrospective cohort study to evaluate the occurrence of bacteremia and associated mortality among hospitalized patients who were seropositive for the human immunodeficiency virus (HIV) and who developed fever and neutropenia following antineoplastic chemotherapy or for other reasons. Review of medical
Lues maligna, or ulceronodular syphilis, in a man infected with human immunodeficiency virus: case report and review.: Clin Infect Dis. 1995 Feb;20(2):387-90. Unique Identifier : AIDSLINE MED/95260944; Sands M; Markus A; Division of Infectious Diseases (Department of Medicine),; Baystate Medical Center, Springfield, Massachusetts 01199, USA.; A 30-year-old bisexual man who was infected with human immunodeficiency virus (HIV) and had a history of anaphylaxis to penicillin developed lues maligna, or ulceronodular secondary syphilis. Therapy with parenteral erythromycin failed, and he was subsequently treated with ceftriaxone following penicillin desensitizat
Coccidioidomycosis of the central nervous system: neuropathological and vasculopathic manifestations and clinical correlates.: Clin Infect Dis. 1995 Feb;20(2):400-5. Unique Identifier : AIDSLINE MED/95260947; Mischel PS; Vinters HV; Department of Pathology and Laboratory Medicine, UCLA Medical; Center 90024, USA.; Infection due to the fungus Coccidioides immitis, which is endemic to the southwestern United States , is currently occurring in epidemic proportions. Although it usually presents as a subclinical infection or a mild, self-limited pulmonary infection, disseminated infection can occur, e
Progressive immunodeficiency and fatal pneumonitis associated with human herpesvirus 6 infection in an infant.: Clin Infect Dis. 1995 Feb;20(2):406-13. Unique Identifier : AIDSLINE MED/95260948; Knox KK; Pietryga D; Harrington DJ; Franciosi R; Carrigan DR; Department of Pathology, Medical College of Wisconsin, Milwaukee; 53226, USA.; Human herpesvirus 6 (HHV-6), an important opportunistic pathogen in immunocompromised patients, causes fatal pneumonitis, encephalitis, and bone marrow suppression. Its ability to infect and destroy T lymphocytes may allow it to synergize with the human immunodeficiency virus in the destruction of lymphoid tissues in
Re-emergence of tuberculosis [editorial]: Curr Opin Obstet Gynecol. 1994 Aug;6(4):373-6. Unique Identifier : AIDSLINE MED/95261004; Baker DA; Tuberculosis (TB) has remained a major infectious disease in the world. With the AIDS epidemic, the emergence of TB as a cause of severe and life-threatening infection has become a common-place occurrence in many countries. In the USA, the increase of new cases of TB average at the rate of 20% each year. Of great alar
HIV infections in women.: Curr Opin Obstet Gynecol. 1994 Aug;6(4):383-8. Unique Identifier : AIDSLINE MED/95261006; Spence MR; Public Health and Preventive Medicine, Hahnemann University; School of Medicine, Philadelphia, Pennsylvania.; Women constitute the most rapidly growing group of individuals in the USA diagnosed with AIDS. Additionally, 35% of these individuals acquired their infection through heterosexual contact. In view of this and the many gender-specific problems that are encountered in immunocompromised women it is critical that our know
Passive immune therapy in acquired immunodeficiency syndrome [letter; comment]: Blood. 1995 May 15;85(10):2996-7. Unique Identifier : AIDSLINE MED/95261071; MacKenzie MR; Holland PV
Gender differences in adoption of AIDS preventive behaviors: implications for women's AIDS education programs.: Womens Health Issues. 1995 Spring;5(1):21-6. Unique Identifier : AIDSLINE MED/95261182; Bowd AD; Loos CH; Faculty of Education, Lakehead University, Thunder Bay, Ontario,; Canada.
Knowledge and attitudes related to AIDS among African-American women.: Ethn Dis. 1994 Winter;4(1):68-76. Unique Identifier : AIDSLINE MED/95261276; Slonim-Nevo V; Auslander WF; Munro JF; Ozawa MN; Ben-Gurion University of the Negev, Beer-Sheva, Israel.; We explored knowledge and perceptions related to AIDS prevention among African-American women who reside in a low-income urban community. The results are based on a short survey and discussions of three focus groups, divided according to the respondents ages. Results of the study indicate that the respondents were le
Cancer, immune function, and physical activity.: Can J Appl Physiol. 1995 Mar;20(1):1-25. Unique Identifier : AIDSLINE MED/95261315; Shephard RJ; Shek PN; School of Physical & Health Education, Univ. of Toronto, Ont.; Despite the problems of interpreting epidemiological studies and the difficulty in developing appropriate animal models, there is growing evidence that moderate habitual physical activity can protect against certain types of neoplasm, particularly tumors of the colon and the female reproductive tract. Exercise program
Inhibitory effects of pentamidine on N-methyl-D-aspartate (NMDA) receptor/channels in the rat brain.: Biol Pharm Bull. 1995 Feb;18(2):234-8. Unique Identifier : AIDSLINE MED/95261341; Kitamura Y; Arima T; Sato T; Nakamura J; Nomura Y; Department of Pharmacology, Faculty of Pharmaceutical Sciences,; Hokkaido University, Sapporo, Japan.; Effects of pentamidine, a therapeutic drug for Pneumocystis carinii pneumonia (PCP) in acquired immunodeficiency syndrome (AIDS), on specific bindings of [3H](+)-5-methyl-10,11-dihydro-5H- dibenzo[a,d]cyclohepten-5,11-imine maleate (MK-801) and [3H]nitrendipine were investigated in crude synaptic membranes (CSM) of ra
A trans-dominant mutation in human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp41 inhibits membrane fusion when expressed in target cells.: Mol Membr Biol. 1994 Jul-Sep;11(3):165-9. Unique Identifier : AIDSLINE MED/95261438; Elson HF; Dimitrov DS; Blumenthal R; Section on Membrane Structure and Function, National Cancer; Institute, National Institutes of Health, Bethesda, MD 20892.; A recombinant vaccinia virus was used to express a mutation in the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp120-gp41. In this mutant protein, the second amino acid in the N-terminal region of gp41 has been converted from a hydrophobic valine residue to the polar glutamate. When recombinant v
AIDS and HIV-1 infection in the United Kingdom: monthly report [published errata appear in Commun Dis Rep CDR Wkly 1995 Apr 28;5(17):84 and 1995 May 19;5(20):98]: Commun Dis Rep CDR Wkly. 1995 Apr 21;5(16):77-80. Unique Identifier : AIDSLINE MED/95261442
Tracking trends and treatment patterns for AIDS and HIV made easier [news]: Nurs Spectr (Wash D C). 1995 Apr 3;5(7):4. Unique Identifier : AIDSLINE MED/95261502
[Bronchiectasis associated with human immunodeficiency virus infection]: Arch Bronconeumol. 1995 Apr;31(4):181-3. Unique Identifier : AIDSLINE MED/95261634; Izquierdo Patron M; Villena Garrido MV; Servicio de Neumologia, Hospital 12 de Octubre, Madrid.; The precise incidence of bronchiectasis (BCH) in individuals infected by human immunodeficiency virus (HIV) is unknown. Because such knowledge can imply different diagnostic procedures, prognosis and treatment, we report a relevant case in which clinical and radiological signs led to suspicion of BCH which was confirm
Crystal structures of HIV-2 protease in complex with inhibitors containing the hydroxyethylamine dipeptide isostere.: Structure. 1995 Jan 15;3(1):33-40. Unique Identifier : AIDSLINE MED/95261703; Tong L; Pav S; Mui S; Lamarre D; Yoakim C; Beaulieu P; Anderson PC; Department of Medicinal Chemistry, Boehringer Ingelheim; Pharmaceuticals Inc., Ridgefield, CT 06877, USA.; BACKGROUND: The HIV protease is essential for the life cycle of the virus and is an important target for the development of therapeutic treatments against AIDS. The structures of HIV protease in complex with different inhibitors have helped in understanding the interactions between inhibitors and the protease and in t
A N-methyl-D-aspartate receptor-mediated neurotoxic effect of aspartate-based hydroxamate compounds in rat primary neuronal cultures.: Brain Res. 1995 Jan 30;670(2):313-6. Unique Identifier : AIDSLINE MED/95261780; Lockhart BP; Hamedi-Sangsari F; Vignon J; Privat A; Vila J; INSERM U-336, Ecole Nationale Superieure de Chimie, Montpellier,; France.; In a previous study (Lockhart et al., Brain Res., 630 (1993) 32-40) we demonstrated a NMDA receptor-mediated neurotoxic effect for the anti-HIV drugs D-aspartate beta-hydroxamate and structurally related analogues in rat primary cortical neurons. Herein, we have examined the neurotoxic action and pharmacology of a nov
Clostridium difficile-associated diarrhoea in patients with human immunodeficiency virus infection: a case-control study.: Eur J Gastroenterol Hepatol. 1995 Mar;7(3):259-63. Unique Identifier : AIDSLINE MED/95261899; Tumbarello M; Tacconelli E; Leone F; Cauda R; Ortona L; Department of Infectious Diseases, Catholic University, Rome,; Italy.; OBJECTIVE: To evaluate the prevalence of, risk factors for, treatment and outcome of Clostridium difficile-associated diarrhoea (CDAD) in patients with human immunodeficiency virus (HIV) infection. DESIGN: A prospective case-control study, conducted between January 1992 and April 1994. SETTING: Department of Infectiou
Guide to HIV care defended [letter]: Can Med Assoc J. 1995 May 15;152(10):1588. Unique Identifier : AIDSLINE MED/95262048; de Burger R
Guide to HIV care defended [letter]: Can Med Assoc J. 1995 May 15;152(10):1588-9. Unique Identifier : AIDSLINE MED/95262049; Perkins RL
Informed consent and blood transfusions: what does Krever's interim report mean to doctors?: Can Med Assoc J. 1995 May 15;152(10):1663-5. Unique Identifier : AIDSLINE MED/95262056; Capen K; What implications does the interim report of the Krever inquiry that is studying Canada s blood-supply system hold for doctors? The report notes that until recently, few physicians talked about the risks of a blood transfusion with their patients and few hospitals considered asking patients to sign a consent form befo
Cytokine response to inactivated Candida albicans in mice.: Cell Immunol. 1995 May;162(2):256-64. Unique Identifier : AIDSLINE MED/95262164; Rosati E; Scaringi L; Cornacchione P; Fettucciari K; Sabatini R; Rossi R; Marconi P; Department of Clinical Medicine, University of Perugia,; Policlinico Monteluce, Italy.; Inactivated Candida albicans (CA) cells induce strong activation of natural cytotoxic effectors in mice. In the present study we examined the expression of cytokine genes involved in the immune response to CA. It has been reported that differential cytokine production by natural immune cells is important for regulatin
Self-treatment of malaria in a rural area of western Kenya.: Bull World Health Organ. 1995;73(2):229-36. Unique Identifier : AIDSLINE MED/95262208; Ruebush TK; Kern MK; Campbell CC; Oloo AJ; Division of Parasitic Diseases (F-22), Centers for Disease; Control and Prevention (CDC), Chamblee, GA 30341-3724, USA.; Reported are the results of a study of residents knowledge about malaria and antimalarial drugs and of their treatment-seeking behaviour in a rural area of western Kenya . The study subjects were generally well-informed about the symptoms of the disease. Malaria was perceived as a r
Visceral leishmaniasis in HIV-infected patients in the south of France.: Bull World Health Organ. 1995;73(2):245-6. Unique Identifier : AIDSLINE MED/95262210; Dereure J; Reynes J; Pratlong F; Lamaury I; Rioux JA; Janbon F; Dedet JP; Laboratoire d'Ecologie medicale et de Pathologie parasitaire,; Montpellier, France.; Between 1989 and 1993, investigations by classical parasitological procedures of 139 HIV-infected adults living in visceral leishmaniasis (VL) endemic areas showed that 10 of them (7.2%) were positive for Leishmania (by stained smears and culture). In the same period we identified 15 VL cases in patients not infected
The level of the serum opsonin, mannan-binding protein in HIV-1 antibody-positive patients.: Clin Exp Immunol. 1995 May;100(2):219-22. Unique Identifier : AIDSLINE MED/95262276; Nielsen SL; Andersen PL; Koch C; Jensenius JC; Thiel S; Department of Infectious Diseases, Marselisborg Hospital, Aarhus,; Denmark.; The concentrations of mannan-binding protein (MBP) in consecutive samples from 10 HIV+ persons were estimated using an ELISA based on polyclonal rabbit anti-MBP. The changes in MBP with time were similar in HIV+ and HIV- persons, and did not appear to be of clinical significance. MBP was determined in a further 70 per
Inhibition of ex vivo proinflammatory cytokine secretion in fatal Mycobacterium tuberculosis infection.: Clin Exp Immunol. 1995 May;100(2):233-8. Unique Identifier : AIDSLINE MED/95262279; Friedland JS; Hartley JC; Hartley CG; Shattock RJ; Griffin GE; Division of Communicable Diseases, St. George's Hospital Medical; School, London, UK.; Tuberculosis is characterized by fever, weight loss, a prolonged acute-phase protein response and granuloma formation. These characteristics may partly be due to action of proinflammatory cytokines tumour necrosis factor (TNF), IL-6 and IL-8. We investigated plasma concentrations of these cytokines before and after ex
Dichotomy of the T cell response to Leishmania antigens in patients suffering from cutaneous leishmaniasis; absence or scarcity of Th1 activity is associated with severe infections.: Clin Exp Immunol. 1995 May;100(2):239-45. Unique Identifier : AIDSLINE MED/95262280; Gaafar A; Kharazmi A; Ismail A; Kemp M; Hey A; Christensen CB; Dafalla M; el Kadaro AY; el Hassan AM; Theander TG; Institute of Tropical Medicine, MRC, Khartoum, Sudan.; The T cell response was studied in 25 patients suffering from cutaneous leishmaniasis caused by Leishmania major with severe (n = 10) and mild (n = 15) disease manifestations. Peripheral blood mononuclear cells (PBMC) from the patients were activated by sonicates of Leishmania promastigotes (LMP) and amastigotes (LDA)
The influence of allo-class II MHC-specific Th2 cells on the generation of CD4 and CD8 cytotoxic T cells to associated class I and class II MHC alloantigen.: Clin Exp Immunol. 1995 May;100(2):359-65. Unique Identifier : AIDSLINE MED/95262297; Wood PJ; Cossens IA; School of Biological Sciences, University of Manchester, UK.; There is considerable interest in whether CD4 T cell function can affect the outcome of allogeneic transplants. In mice tolerant to an isolated class II MHC disparity, the normal Th1 activity in vitro associated with graft rejection is switched to Th2 in tolerant animals. Because clinical transplants involve multiple
Comparison of blood and synovial fluid lymphocyte subsets in rheumatoid arthritis and osteoarthritis.: Clin Rheumatol. 1995 Jan;14(1):43-50. Unique Identifier : AIDSLINE MED/95262366; Kuryliszyn-Moskal A; Department of Rheumatology, Medical School, Bialystok, Poland.; Immunoregulatory T-cell deficiency is thought to underlie pathogenesis of rheumatoid arthritis (RA) as a systemic autoimmunopathy. The aim of this study was a simultaneous analysis of peripheral blood and synovial lymphocyte subsets (Ly-SS) of RA patients as compared to patients with locally active osteoarthritis (OA)
Peripheral blood lymphocyte subsets in polymyalgia rheumatica.: Clin Rheumatol. 1995 Jan;14(1):62-7. Unique Identifier : AIDSLINE MED/95262369; Uddhammar A; Roos G; Nasman B; Dahlqvist SR; Department of Rheumatology, Umea University Hospital, Sweden.; Peripheral blood lymphocytes from 23 patients with polymyalgia rheumatica (PMR) were characterized using monoclonal antibodies and flow cytometry in a two-year prospective study. There were no significant differences in absolute numbers or relative percentages of lymphocytes or CD3+, CD4+, CD8+ T cells or the CD4+ T c
The usefulness of CD4/CD8 ratio evaluation in monitoring of ovarian cancer patients.: Eur J Gynaecol Oncol. 1995;16(1):54-8. Unique Identifier : AIDSLINE MED/95262762; Markowska J; Lacki JK; Jaroszewski J; Wiktorowicz K; Dept of Oncology, University School of Medicine Poznan, Poland.; Twenty-seven ovarian cancer patients were observed for twenty-four months. The patients were grouped as follows: Group I-with complete (CR) or partial remission (PR), Group II-with stable disease (SD), Group III-with progression (PD) of the disease. In all patients, T lymphocyte phenotypes were estimated in peritoneal
Closed video transurethral resection of the prostate for the prevention of infection.: Eur Urol. 1995;27(1):31-3. Unique Identifier : AIDSLINE MED/95262783; Morita M; Department of Urology, Sendai Shakaihoken Hospital, Japan.; An instrument with which safe and clean video transurethral resection of the prostate (video TURP) can be performed has been developed by the author; its use could minimize the risk to the operating staff of being infected by such dangerous viruses as human immunodeficiency virus (HIV), hepatitis B virus (HBV), and he
Renal aspergillosis and AIDS.: Eur Urol. 1995;27(2):167-9. Unique Identifier : AIDSLINE MED/95262809; Martinez-Jabaloyas J; Osca JM; Ruiz JL; Beamud A; Blanes M; Jimenez-Cruz JF; Department of Urology, La Fe Hospital, Valencia, Spain.; Primary renal aspergillosis is an extremely rare entity. Only 19 cases have been reported, 3 of them in patients with AIDS. We report one new case of renal aspergillosis in a patient with AIDS. His disease pattern was multiple bilateral renal abscesses with a normal excretory pathway. The treatment established was per
Heterogeneity among zymodemes of Leishmania infantum from HIV-positive patients with visceral leishmaniasis in south Italy.: FEMS Microbiol Lett. 1995 Apr 15;128(1):33-8. Unique Identifier : AIDSLINE MED/95262887; Gramiccia M; Gradoni L; Troiani M; Laboratorio di Parassitologia, Istituto Superiore di Sanita,; Rome, Italy.; Eleven zymodemes of Leishmania infantum were identified among 38 parasite stocks isolated from Italian HIV-positive patients with visceral leishmaniasis (VL). Only one zymodeme is a common agent of Mediterranean VL in HIV-negative individuals, five zymodemes usually cause simple, self-resolving cutaneous leishmaniasis
Mycoplasmas regulate HIV-LTR-dependent gene expression.: FEMS Microbiol Lett. 1995 Apr 15;128(1):63-8. Unique Identifier : AIDSLINE MED/95262890; Nir-Paz R; Israel S; Honigman A; Kahane I; Department of Membrane, Hebrew University-Hadassah Medical; School, Jerusalem, Israel.; Mycoplasmas have been incriminated in setting the stage for HIV infection and full-blown AIDS. We tested the possible involvement of mycoplasmas in activation of HIV. Two cell lines, 293 fibroblasts and Jurkat CD4+ T-cells, transfected with plasmids harboring a transcription fusion construct between HIV-long terminal
The toxicity of azidothymidine (AZT) on human and animal cells in culture at concentrations used for antiviral therapy.: Genetica. 1995;95(1-3):103-9. Unique Identifier : AIDSLINE MED/95262906; Chiu DT; Duesberg PH; Dept. of Molecular and Cell Biology, University of California,; Berkeley 94720, USA.; AZT , a chain terminator of DNA synthesis originally developed for chemotherapy, is now prescribed as an anti-human immunodeficiency virus (HIV) drug at 500 to 1500 mg/person/day, which corresponds to 20 to 60 microM AZT. The human dosage is based on a
Five myths about AIDS that have misdirected research and treatment.: Genetica. 1995;95(1-3):111-32. Unique Identifier : AIDSLINE MED/95262907; Root-Bernstein RS; Department of Physiology, Michigan State University, East Lansing; 48824, USA.; A number of widely repeated and factually incorrect myths have pervaded the AIDS research literature, misdirecting research and treatment. Five of the most outstanding are: 1) that all risk groups develop AIDS at the same rate following HIV infection; 2) that there are no true seroreversions following HIV infection; 3
Semen alloantigens and lymphocytotoxic antibodies in AIDS and ICL.: Genetica. 1995;95(1-3):133-56. Unique Identifier : AIDSLINE MED/95262908; Root-Bernstein RS; DeWitt SH; Department of Physiology, Michigan State University, East Lansing; 48824, USA.; More than 90% of people with AIDS develop circulating immune complexes (CICs) and lymphocytotoxic antibodies (LCTAs). Animals infected with HIV, however, never display CICs or LCTAs, and remain healthy. Similarly, HIV-infected people who do not develop CICs or LCTAs also do not progress to AIDS. The appearance of CICs
Measuring inhalant nitrite exposure in gay men: implications for elucidating the etiology of AIDS-related Kaposi's sarcoma.: Genetica. 1995;95(1-3):157-64. Unique Identifier : AIDSLINE MED/95262909; Haverkos HW; Drotman DP; NIDA/NIH, Rockville, MD 20857, USA.; We reviewed 12 epidemiologic studies conducted among gay men with AIDS to examine the role of potential cofactors in the development of KS. Aspects of the studies reviewed include basic study design, wording of the questionnaires, and published results comparing KS patients with those who developed opportunistic inf
HIV as a surrogate marker for drug use: a re-analysis of the San Francisco Men's Health Study.: Genetica. 1995;95(1-3):165-71. Unique Identifier : AIDSLINE MED/95262910; Ellison BJ; Downey AB; Duesberg PH; Department of Molecular and Cell Biology, University of; California, Berkeley 94720, USA.; Our analysis of drug use and morbidity data from a cohort of 1034 men yields the following results: 1) HIV infection is a strong indicator of drug use-HIV-positive respondents reported an average lifetime dose of recreational drugs (excluding marijuana) 2.3 times higher than HIV-negative respondents. 2) Homosexuality
The epidemiology and transmission of AIDS: a hypothesis linking behavioural and biological determinants to time, person and place.: Genetica. 1995;95(1-3):173-93. Unique Identifier : AIDSLINE MED/95262911; Stewart GT; Emeritus Professor of Public Health, University of Glasgow, UK.; Epidemiologically, the Acquired Immune Deficiency Syndrome, AIDS, is transmitted and distributed in the USA and Europe almost entirely in well-defined subsets of populations engaging in, or subjected to, the effects of behaviours which carry high risks of genital and systemic infections. The persons predominantly affe
A hypothetical disease of the immune system that may bear some relation to the acquired immune deficiency syndrome.: Genetica. 1995;95(1-3):195-7. Unique Identifier : AIDSLINE MED/95262912; Mullis KB
A critical analysis of the HIV-T4-cell-AIDS hypothesis.: Genetica. 1995;95(1-3):5-24. Unique Identifier : AIDSLINE MED/95262914; Papadopulos-Eleopulos E; Turner VF; Papadimitriou JM; Causer D; Hedland-Thomas B; Page BA; Department of Medical Physics, Royal Perth Hospital, Western; Australia.; The data generally accepted as proving the HIV theory of AIDS, HIV cytopathy, destruction of T4 lymphocytes, and the relationship between T4 cells, HIV and the acquired immune deficiency clinical syndrome are critically evaluated. It is concluded these data do not prove that HIV preferentially destroys T4 cells or has
Foreign-protein-mediated immunodeficiency in hemophiliacs with and without HIV.: Genetica. 1995;95(1-3):51-70. Unique Identifier : AIDSLINE MED/95262915; Duesberg PH; Dept. of Molecular and Cell Biology, University of California at; Berkeley 94720, USA.; Hemophilia-AIDS has been interpreted in terms of two hypotheses: the foreign-protein-AIDS hypothesis and the Human Immunodeficiency Virus (HIV)-AIDS hypothesis. The foreign-protein-AIDS hypothesis holds that proteins contaminating commercial clotting factor VIII cause immunosuppression. The foreign-protein hypothesis,
Critical analysis of the current views on the nature of AIDS.: Genetica. 1995;95(1-3):71-90. Unique Identifier : AIDSLINE MED/95262916; Koliadin VL; Kharkov Aviation Institute, Ukraine.
AZT toxicity and AIDS prophylaxis: is AZT beneficial for HIV+ asymptomatic persons with 500 or more T4 cells per cubic millimeter?: Genetica. 1995;95(1-3):91-101. Unique Identifier : AIDSLINE MED/95262917; Zaretsky MD; Department of Molecular and Cell Biology, University of; California, Berkeley 94720, USA.; Analyses of the effects of prophylactic use of zidovudine ( AZT ) on progression to acquired immune deficiency syndrome (AIDS) in human immunodeficiency virus seropositive (HIV+) asymptomatic persons with T4 lymphocyte (CD4+) cell counts > or = 500 mm3
[Role of TH1 and TH2 in the pathogenesis of AIDS and various other diseases]: Harefuah. 1995 Feb 15;128(4):228-3. Unique Identifier : AIDSLINE MED/95262989; Kalinkovich A; Weisman Z; Bentwich Z
Evaluating a designated family planning clinic within a genitourinary medicine clinic [see comments]: Genitourin Med. 1995 Apr;71(2):106-8. Unique Identifier : AIDSLINE MED/95263057; Carlin EM; Russell JM; Sibley K; Boag FC; St Stephen's Clinic, Chelsea and Westminster Hospital, London,; UK.; OBJECTIVE--To evaluate an integrated family planning clinic (FPC) established by genitourinary medicine (GUM) staff held within a GUM women-only clinic (WOC). DESIGN--A retrospective case note review of women attending the FPC during the first year January-December 1992. RESULTS--One hundred and thirteen women, aged 1
Arsphenamine jaundice and the recognition of instrument-borne virus infection.: Genitourin Med. 1995 Apr;71(2):109-19. Unique Identifier : AIDSLINE MED/95263058; Mortimer PP; Hepatitis and Retrovirus Laboratory, Virus Reference Division,; London, UK.; Soon after its introduction in 1910, intravenous arsphenamine treatment for syphilis was found to be complicated by jaundice. The underlying cause, unsterile syringes and needles, was eventually recognised in the early 1940s, mainly through the efforts of British Army investigators. The infection most often transmitte
Incidence of symptomatic urinary tract infections in HIV seropositive patients and the use of cotrimoxazole as prophylaxis against Pneumocystis carinii pneumonia.: Genitourin Med. 1995 Apr;71(2):120-2. Unique Identifier : AIDSLINE MED/95263059; Evans JK; McOwan A; Hillman RJ; Forster GE; Ambrose King Centre, Royal London Hospital, UK.; OBJECTIVES--To determine the incidence of symptomatic urinary tract infections in HIV seropositive patients and to assess whether this varies with stage of disease, risk group or the use of co-trimoxazole as prophylaxis against Pneumocystis carinii pneumonia. METHODS--A retrospective case note review of 175 HIV-infect
P24 antigen detection, viral isolation, DNA-PCR and in vitro antibody production for the diagnosis of HIV-1 latent infection in heterosexual women at high risk for HIV-1 infection.: Genitourin Med. 1995 Apr;71(2):123-5. Unique Identifier : AIDSLINE MED/95263060; Di Stefano M; Fiore JR; Chironna M; Buccoliero G; Romanelli C; La Grasta L; Quarto M; Angarano G; Pastore G; Clinic of Infectious Diseases, University of Bari, Italy.; INTRODUCTION--The report of the existence of at-risk seronegative subjects, latently infected with HIV-1 and producing in vitro HIV-1 specific antibodies, prompted the authors to evaluate extensively twenty-five heterosexual HIV-1 seronegative women at high risk for HIV-1 infection. MATERIAL AND METHODS--The capabilit
A non-Hodgkin's lymphoma in a patient with HIV-2 infection [letter]: Genitourin Med. 1995 Apr;71(2):129. Unique Identifier : AIDSLINE MED/95263062; Colebunders R; De Vuyst H; Verstraeten T; Schroyens W; Van Marck E
Prurigo nodularis in an HIV positive man [letter]: Genitourin Med. 1995 Apr;71(2):129-30. Unique Identifier : AIDSLINE MED/95263063; Kundu A; Wade AA; Ilchyshyn A
Pancreatitis associated with aerosolised pentamidine [letter]: Genitourin Med. 1995 Apr;71(2):130-1. Unique Identifier : AIDSLINE MED/95263064; Singh G; el-Gadi SM; Sparks RA
More severe course of delta hepatitis in HIV-infected patients [L] [letter]: Genitourin Med. 1995 Apr;71(2):132-3. Unique Identifier : AIDSLINE MED/95263066; de Pouplana M; Soriano V; Samaniego JG; Enriquez A; Munoz F; Gonzalez-Lahoz J
Kaposi sarcoma in Germany [letter; comment]: Genitourin Med. 1995 Apr;71(2):136. Unique Identifier : AIDSLINE MED/95263070; Matondo P; Sivapalan S
Serological screening for sexually transmitted infections in pregnancy: is there any value in re-screening for HIV and syphilis at the time of delivery?: Genitourin Med. 1995 Apr;71(2):65-7. Unique Identifier : AIDSLINE MED/95263072; Qolohle DC; Hoosen AA; Moodley J; Smith AN; Mlisana KP; Department of Obstetrics and Gynaecology, University of Natal,; Durban, South Africa.; OBJECTIVE--The aim of this study was to assess the prevalence of syphilis, human immunodeficiency virus (HIV), and hepatitis B virus (HBV) infections in women at the time of delivery, and to determine the seroconversion rates for syphilis and HIV infections from initial booking visit to delivery. SETTING--The labour w
Pneumococcal vaccine and HIV infection: report of a vaccine failure and reappraisal of its value in clinical practice.: Genitourin Med. 1995 Apr;71(2):71-2. Unique Identifier : AIDSLINE MED/95263074; Willocks LJ; Vithayathil K; Tang A; Noone A; PHLS Communicable Disease Surveillance Centre, London, UK.; A clinical failure of pneumococcal vaccine is reported. A 22 year old African woman was given 23-valent pneumococcal vaccine at her initial presentation with HIV infection. She was asymptomatic and had a CD4+ lymphocyte count above 500 cells/mm3. Eighteen months later she died of meningitis and septicaemia due to Stre
Bronchopulmonary infection with Pseudomonas aeruginosa in patients infected with human immunodeficiency virus [see comments]: Genitourin Med. 1995 Apr;71(2):73-7. Unique Identifier : AIDSLINE MED/95263075; Ali NJ; Kessel D; Miller RF; Department of Medicine, University College London Medical School,; UK.; BACKGROUND--Pseudomonas aeruginosa infection is uncommon in HIV infected patients and is usually nosocomially acquired and associated with risk factors such as neutropenia or central lines. We have recently noted an increase in the number of respiratory isolates of Ps aeruginosa in hospitalised HIV positive patients a
Nonoxynol-9 use, genital ulcers, and HIV infection in a cohort of sex workers.: Genitourin Med. 1995 Apr;71(2):78-81. Unique Identifier : AIDSLINE MED/95263076; Weir SS; Roddy RE; Zekeng L; Feldblum PJ; Family Health International, Research Triangle Park, North; Carolina 27709, USA.; OBJECTIVES--To measure the associations between use of nonoxynol-9 (N-9) and incidence of genital ulcers, and incident ulcers and HIV seroconversion. METHODS--In a study of barrier contraceptive use and HIV infection, 273 female sex workers used condoms and 100 mg N-9 suppositories, and recorded sexual activity on coi
AIDS risk behaviours and correlates in teenagers attending sexually transmitted diseases clinics in Los Angeles.: Genitourin Med. 1995 Apr;71(2):82-7. Unique Identifier : AIDSLINE MED/95263077; Maxwell AE; Bastani R; Yan KX; Division of Cancer Prevention and Control Research, UCLA Jonsson; Comprehensive Cancer Center 90024, USA.; OBJECTIVE--Of all age groups, teenagers have the highest rates of sexually transmitted diseases. Therefore, it is particularly important to target interventions at this group. Teenagers attending STD clinics are at particularly high risk since behaviours that lead to an STD can also result in the transmission of HIV.
BCG vaccination in India and tuberculosis in children: newer facets.: Indian J Pediatr. 1994 Sep-Oct;61(5):451-62. Unique Identifier : AIDSLINE MED/95263106; Udani PM; Postgraduate Institute of Medical Sciences, Bombay Hospital.; With the extended programme of immunisation and since 1985 the universal programme of immunisation and the coverage status of BCG vaccination in India has been very good, although it is still unsatisfactory in the eastern states. It is emphasized that BCG vaccination cannot prevent
AIDS in children--I [editorial]: Indian J Pediatr. 1994 Sep-Oct;61(5):475-6. Unique Identifier : AIDSLINE MED/95263109; Sen S
The diagnosis and classification of childhood HIV infection and disease.: Indian J Pediatr. 1994 Sep-Oct;61(5):477-90. Unique Identifier : AIDSLINE MED/95263110; Sen S; Charak Palika Hospital, Moti Bagh, New Delhi.
Preventive strategies for pediatric AIDS.: Indian J Pediatr. 1994 Sep-Oct;61(5):491-6. Unique Identifier : AIDSLINE MED/95263111; Lal S; Sengupta D; National AIDS Control Organisation, Ministry of Health & Family; Welfare, New Delhi.
Pathology of AIDS in children.: Indian J Pediatr. 1994 Sep-Oct;61(5):497-512. Unique Identifier : AIDSLINE MED/95263112; Joshi VV; School of Medicine, Department of Pathology and Laboratory; Medicine, East Carolina University, Greenville, North Carolina; 27859-4354, USA.; AIDS in children is a multisystem disease. The various infections, degenerative, proliferative and vascular lesions can be classified into three categories based on the known, presumed or undetermined pathogenesis. The primary lesions are due to HIV infection. The associated lesions are related to direct or indirect s
Diagnosis and management of opportunistic infections in childhood AIDS.: Indian J Pediatr. 1994 Sep-Oct;61(5):513-24. Unique Identifier : AIDSLINE MED/95263113; Lal S; Sengupta D; National AIDS Control Organization, Ministry of Health & Family; Welfare, Government of India, New Delhi.
Pulmonary diseases in childhood AIDS.: Indian J Pediatr. 1994 Sep-Oct;61(5):525-33. Unique Identifier : AIDSLINE MED/95263114; Somu N; Vijayasekaran D; Ashok TP; Balachandran A; Subramanyam L; Department of Pediatric Respiratory Diseases, Institute of Child; Health, Egmore, Madras.
Vaccines for control of AIDS--an update.: Indian J Pediatr. 1994 Sep-Oct;61(5):535-43. Unique Identifier : AIDSLINE MED/95263115; Sharma KB; World Health Organization, Regional Office for South-East Asia,; New Delhi.
Male-to-female transmission of HIV in a cohort of hemophiliacs--frequency, risk factors and effect of sexual counseling.: Infection. 1995 Jan-Feb;23(1):29-32. Unique Identifier : AIDSLINE MED/95263151; Rockstroh JK; Ewig S; Bauer T; Luchters G; Oldenburg J; Bailly E; Kaiser R; Schneweis KE; Brackmann HH; Dengler HJ; et al; Medizinische Universitatsklinik und Poliklinik, Bonn, Germany.; The incidence of male-to-female transmission of HIV infection was studied in a population of 198 sexual partners of hemophiliacs who tested HIV positive since 1984. The follow-up observation period was 1987-1992. Transmission occurred in 20 (10%) cases. The analysis of risk factors for transmission was performed in a
HTLV-II does not adversely affect the natural history of HIV-1 infection in intravenous drug users [letter]: Infection. 1995 Jan-Feb;23(1):63. Unique Identifier : AIDSLINE MED/95263161; Magnani G; Elia G; Casoli C; Calzetti C; Degli Antoni A; Fiaccadori F
Activation of tumor necrosis factor--alpha system in HIV-1 infection: association with markers of immune activation.: Infection. 1995 Jan-Feb;23(1):9-15. Unique Identifier : AIDSLINE MED/95263164; Aukrust P; Liabakk NB; Muller F; Espevik T; Froland SS; Medical Dept. A, University of Oslo, National Hospital,; Rikshospitalet, Norway.; The relationships between serum levels of soluble tumor necrosis factor receptors (sTNFRs) and other prognostic and immunological parameters in different immunological subgroups of 64 HIV-1 infected patients were studied. In the patient group as a whole, the raised serum levels of sTNFRs were significantly inversely c
Bilateral subclavian vein thrombosis in a patient with acquired immunodeficiency syndrome.: J Am Osteopath Assoc. 1995 Apr;95(4):276-7. Unique Identifier : AIDSLINE MED/95263295; Bayer DD; Sorbello AF; Condoluci DV; Division of Infectious Diseases, University of Medicine and; Dentistry of New Jersey--School of Osteopathic Medicine,; Stratford, USA.; Bilateral subclavian vein thrombi developed, in the presence of a Groshong catheter, in a patient with the acquired immunodeficiency syndrome (AIDS) and disseminated cytomegalovirus infection. Thrombosis is an uncommon complication of AIDS, and bilateral subclavian thrombi are rare
Evidence in support of a role for human T-cell leukemia virus type I Tax in activating NF-kappa B via stimulation of signaling pathways.: J Biol Chem. 1995 May 19;270(20):11745-8. Unique Identifier : AIDSLINE MED/95263510; Kanno T; Brown K; Siebenlist U; Laboratory of Immunoregulation, NIAID, National Institutes of; Health, Bethesda, Maryland 20892-1876, USA.; The human T-cell leukemia virus type I Tax protein activates NF-kappa B transcription factors from preformed cytoplasmic pools, including those pools that are retained by the I kappa B-alpha inhibitory protein. Degradation of I kappa B-alpha is enhanced by Tax, resulting in the liberation of some NF-kappa B, which the
An enlarging breast mass in an HIV-seropositive woman.: Hosp Pract (Off Ed). 1995 May 15;30(5):31-2. Unique Identifier : AIDSLINE MED/95263688; Fred HL; University of Texas Health Science Center at Houston, USA.
Social support, quality of life, immune function, and health in persons living with HIV.: J Holist Nurs. 1995 Jun;13(2):174-98. Unique Identifier : AIDSLINE MED/95263968; Nunes JA; Raymond SJ; Nicholas PK; Leuner JD; Webster A; The purpose of this study was to examine the relationship between social support and quality of life in individuals with HIV. Using a descriptive, correlational design, data were collected from 50 HIV-positive individuals who were: (a) participants in support groups at a behavioral medicine unit, (b) inpatient or resp
Whole blood culture for measuring mitogen induced T cell proliferation provides superior correlations with disease state and T cell phenotype in asymptomatic HIV-infected subjects.: J Immunol Methods. 1995 Apr 26;181(2):233-43. Unique Identifier : AIDSLINE MED/95263979; Bocchieri MH; Talle MA; Maltese LM; Ragucci IR; Hwang CC; Goldstein G; Immunobiology Research Institute, Annandale, NJ 08801, USA.; Proliferative responses to a panel of mitogens were compared in parallel for two sources of cells, whole blood (WB) and conventionally prepared peripheral blood mononuclear cells (PBMC), obtained from asymptomatic HIV seropositive and control subjects. Weak but statistically significant correlations of the proliferati
[An autopsy of an HIV infected patient with dilated cardiomyopathy (DCM)]: Kansenshogaku Zasshi. 1995 Feb;69(2):202-7. Unique Identifier : AIDSLINE MED/95264025; Yamaji K; Hayashi J; Tani Y; Ise K; Nakashima K; Kashiwagi S; Department of General Medicine, Kyusyu University Hospital.; A case of a HIV infected 61-year-old bisexual male with dilated cardiomyopathy (DCM) is reported. The death was originally recorded as from undetermined causes, but on autopsy, his heart showed left ventricular dilatation macroscopically, variety in size and vacuolation of cardiomyocyte, partial deciduation of cardiac
[Vasculitis of viral origin. Pathogenesis and therapeutic implications]: J Mal Vasc. 1995;20(1):1-7. Unique Identifier : AIDSLINE MED/95264082; Genereau T; Tri N'Guyen Q; Lortholary O; Cohen P; Guillevin L; Service de Medecine Interne, Hopital Avicenne, Bobigny.; Some viruses are unquestionably the cause of vasculitis, by different mechanisms: circulating immune complexes, cryoglobulinemia and/or direct infection of the blood vessel. The main viruses responsible for vasculitis are hepatitis B & C viruses, cytomegalovirus , parvovirus B19 and
Clinical aspects and treatment outcome in HIV-associated pulmonary tuberculosis: an experience from a Thai referral centre.: J Med Assoc Thai. 1994 Oct;77(10):520-5. Unique Identifier : AIDSLINE MED/95264102; Hongthiamthong P; Riantawan P; Subhannachart P; Fuangtong P; Division of Medicine, Central Chest Hospital, Ministry of Public; Health, Nonthaburi, Thailand.; This case-control study examined the impact of HIV infection on clinical presentation, response to treatment, and outcome of pulmonary tuberculosis. Symptoms, radiographic pattern, sputum direct smear, drug susceptibility, treatment outcome and adverse reactions of 88 HIV-infected patients with newly-diagnosed, cultur
Emotional distress, coping, and adjustment in human immunodeficiency virus infection and acquired immune deficiency syndrome.: J Nerv Ment Dis. 1995 May;183(5):293-8. Unique Identifier : AIDSLINE MED/95264111; Krikorian R; Kay J; Liang WM; Department of Psychiatry, University of Cincinnati College of; Medicine, Ohio 45267-0559, USA.; Fifty-seven ambulatory, human immunodeficiency virus (HIV)-infected patients at various stages of disease progression and 17 HIV seronegative controls were examined in a cross-sectional study with self-administered measures of emotional distress, coping, and adjustment to illness. All infected and control subjects wer
Infection of human fetal astrocytes with HIV-1: viral tropism and the role of cell to cell contact in viral transmission.: J Neuropathol Exp Neurol. 1995 May;54(3):320-30. Unique Identifier : AIDSLINE MED/95264160; Nath A; Hartloper V; Furer M; Fowke KR; Laboratory of Neurovirology, Department of Medical Microbiology,; Winnipeg, Manitoba, Canada.; Astrocyte cultures from human fetal brain were infected with human immunodeficiency virus (HIV) either as free virus or with a chronically infected lymphoblastoid cell line and monitored for signs of infection. The lymphocytotropic strains HIV3B and HIVSF2(ARV-2) but not the monocytotropic strain HIVAda-M infected the
Differential vulnerability of calbindin-immunoreactive neurons in HIV encephalitis.: J Neuropathol Exp Neurol. 1995 May;54(3):350-7. Unique Identifier : AIDSLINE MED/95264163; Masliah E; Ge N; Achim CL; Wiley CA; Department of Neurosciences, University of California, San Diego,; La Jolla 92093-0624, USA.; Recent studies have suggested that the neuronal damage during human immunodeficiency virus encephalitis (HIVE) might be mediated by increased intracellular calcium. Since in vitro studies have shown that calcium-binding proteins protect neurons from calcium-mediated toxicity, we hypothesized that calbindin-expressing
Mechanisms of cell death in brains of patients with AIDS [letter]: J Neuropathol Exp Neurol. 1995 May;54(3):404. Unique Identifier : AIDSLINE MED/95264168; Petito CK
Women living with the human immunodeficiency virus: home-care needs.: J Obstet Gynecol Neonatal Nurs. 1995 Feb;24(2):165-72. Unique Identifier : AIDSLINE MED/95264221; Zelewsky MG; Birchfield M; Department of Community Mental Health, Loyola University,; Chicago, IL, USA.; Strategies for dealing with the complex nursing care needs of women living with human immunodeficiency virus (HIV) disease are discussed. Using the experiences of the authors clinical practices and nursing situations described in the literature, the physical, psychosocial, and behavioral issues surrounding the needs
Epstein-Barr virus in B-cell non-Hodgkin's lymphomas: unexpected infection patterns and different infection incidence in low- and high-grade types.: J Pathol. 1995 Mar;175(3):263-71. Unique Identifier : AIDSLINE MED/95264225; Hummel M; Anagnostopoulos I; Korbjuhn P; Stein H; Institute of Pathology, Klinikum Benjamin Franklin, Free; University Berlin, Germany.; Two hundred and eight cases of B-cell non-Hodgkin s lymphoma (B-NHL) occurring in Europeans without any signs of HIV infection were investigated for their association with an Epstein-Barr virus (EBV) infection. The polymerase chain reaction (PCR) was applied for EBV-DNA detection,
Mononuclear cell thyroiditis in rats with graft-versus-host disease.: J Pathol. 1995 Mar;175(3):349-55. Unique Identifier : AIDSLINE MED/95264235; Fujiwara K; Peszkowski MJ; Larsson A; Yamasaki A; Toda S; Watanabe T; Department of Oral Pathology, Ohu University School of Dentistry,; Koriyama, Japan.; Rats with graft-versus-host disease (GVHD), induced by injecting spleen cells of parental strain rats (Brown Norway ) into non-irradiated (Brown Norway x Lewis) F1 hybrid rats, develop thyroiditis. This is characterized by mononuclear cell infiltration with destruction of the epithe
The vif gene is essential for efficient replication of caprine arthritis encephalitis virus in goat synovial membrane cells and affects the late steps of the virus replication cycle.: J Virol. 1995 Jun;69(6):3247-57. Unique Identifier : AIDSLINE MED/95264411; Harmache A; Bouyac M; Audoly G; Hieblot C; Peveri P; Vigne R; Suzan M; Institut National de la Sante et de la Recherche Medicale; (INSERM) U372, Marseille, France.; Complex retrovirus genomes contain a variable number of accessory genes, among which is the vif gene. We investigated in vitro the role of the vif gene of caprine arthritis encephalitis virus (CAEV) by studying the phenotype of five vif mutants after infection of primary goat synovial membrane (GSM) cells and blood-de
Dual human immunodeficiency virus type 1 infection and recombination in a dually exposed transfusion recipient. The Transfusion Safety Study Group.: J Virol. 1995 Jun;69(6):3273-81. Unique Identifier : AIDSLINE +; Diaz RS; Sabino EC; Mayer A; Mosley JW; Busch MP; Irwin Memorial Blood Centers, San Francisco, California, USA.; We studied a case in which a 2-month-old premature infant was concurrently transfused with packed erythrocytes from two different human immunodeficiency virus type 1 (HIV-1)-seropositive donors in late 1984. The two donors also each singly infected a second infant. Inspection of sequences from portions of the HIV-1 ge
Brucella abortus conjugated with a gp120 or V3 loop peptide derived from human immunodeficiency virus (HIV) type 1 induces neutralizing anti-HIV antibodies, and the V3-B. abortus conjugate is effective even after CD4+ T-cell depletion.: J Virol. 1995 Jun;69(6):3299-307. Unique Identifier : AIDSLINE MED/95264417; Golding B; Inman J; Highet P; Blackburn R; Manischewitz J; Blyveis N; Angus RD; Golding H; Laboratory of Plasma Derivatives, U.S. Food and Drug; Administration, Bethesda, Maryland 20892, USA.; Human immunodeficiency virus type 1 (HIV-1) infection is associated with loss of function and numbers of CD4+ T-helper cells. In order to bypass the requirement for CD4+ cells in antibody responses, we have utilized heat-inactivated Brucella abortus as a carrier. In this study we coupled a 14-mer V3 loop peptide (V3),
Requirement of N-terminal amino acid residues of gp41 for human immunodeficiency virus type 1-mediated cell fusion.: J Virol. 1995 Jun;69(6):3308-14. Unique Identifier : AIDSLINE MED/95264418; Schaal H; Klein M; Gehrmann P; Adams O; Scheid A; Biologisch-Medizinisches Forschungszentrum,; Heinrich-Heine-Universitat, Dusseldorf, Germany.; An expression vector was designed to test the structural requirements of the gp41 N terminus for human immunodeficiency virus type 1-induced membrane fusion. Mutations in the region coding for the N terminus of gp41 were found to disrupt glycoprotein expression because of deleterious effects on the Rev-responsive elem
Nuclear export of the human immunodeficiency virus type 1 nucleocytoplasmic shuttle protein Rev is mediated by its activation domain and is blocked by transdominant negative mutants.: J Virol. 1995 Jun;69(6):3315-23. Unique Identifier : AIDSLINE MED/95264419; Szilvay AM; Brokstad KA; Kopperud R; Haukenes G; Kalland KH; National Centre for Research in Virology, Gade Institute,; University of Bergen, Norway.; The human immunodeficiency virus type 1 nucleocytoplasmic shuttle protein Rev moves repeatedly between the cytoplasm, a perinuclear zone, the nucleoli, and nucleoplasmic speckles. In this study, we demonstrated by both indirect immunofluorescence and Western immunoblot analysis that nuclear exit of Rev transdominant n
Targeting foreign proteins to human immunodeficiency virus particles via fusion with Vpr and Vpx.: J Virol. 1995 Jun;69(6):3389-98. Unique Identifier : AIDSLINE MED/95264427; Wu X; Liu H; Xiao H; Kim J; Seshaiah P; Natsoulis G; Boeke JD; Hahn BH; Kappes JC; Department of Medicine, University of Alabama at Birmingham; 35294.; The human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vpr and Vpx proteins are packaged into virions through virus type-specific interactions with the Gag polyprotein precursor. To examine whether HIV-1 Vpr (Vpr1) and HIV-2 Vpx (Vpx2) could be used to target foreign proteins to the HIV particle, their open reading
Reduced glycosylation of human cell lines increases susceptibility to CD4-independent infection by human immunodeficiency virus type 2 (LAV-2/B).: J Virol. 1995 Jun;69(6):3399-406. Unique Identifier : AIDSLINE MED/95264428; Talbot SJ; Weiss RA; Schulz TF; Chester Beatty Laboratories, Institute for Cancer Research,; London, United Kingdom.; The human immunodeficiency virus type 2 (HIV-2) strain LAV-2/B is able to infect a variety of human cell lines via a CD4-independent pathway. We have used the glycosylation inhibitors tunicamycin, swainsonine, and deoxymannojirimycin to further characterize this putative alternative receptor for HIV-2 (LAV-2/B). These
The spacer peptide between human immunodeficiency virus capsid and nucleocapsid proteins is essential for ordered assembly and viral infectivity.: J Virol. 1995 Jun;69(6):3407-19. Unique Identifier : AIDSLINE MED/95264429; Krausslich HG; Facke M; Heuser AM; Konvalinka J; Zentgraf H; Angewandte Tumorvirologie, Deutsches Krebsforschungszentrum,; Heidelberg, Germany.; Morphogenesis of retroviruses involves ordered assembly of the structural Gag- and Gag-Pol polyproteins, with subsequent budding from the plasma membrane and proteolytic cleavage by the viral proteinase (PR). Two cleavage sites exist between the capsid (CA) and nucleocapsid (NC) domains of the human immunodeficiency v
Protein domains involved in both in vivo and in vitro interactions between human T-cell leukemia virus type I tax and CREB.: J Virol. 1995 Jun;69(6):3420-32. Unique Identifier : AIDSLINE MED/95264430; Yin MJ; Paulssen EJ; Seeler JS; Gaynor RB; Department of Internal Medicine, University of Texas Southwestern; Medical Center, Dallas 75235-8594, USA.; Gene expression from the human T-cell leukemia virus type I (HTLV-I) long terminal repeat (LTR) is mediated by three cis-acting regulatory elements known as 21-bp repeats and the transactivator protein Tax. The 21-bp repeats can be subdivided into three motifs known as A, B, and C, each of which is important for maxim
The envelope glycoprotein of an amphotropic murine retrovirus binds specifically to the cellular receptor/phosphate transporter of susceptible species.: J Virol. 1995 Jun;69(6):3433-40. Unique Identifier : AIDSLINE MED/95264431; Kozak SL; Siess DC; Kavanaugh MP; Miller AD; Kabat D; Department of Biochemistry and Molecular Biology, Oregon Health; Sciences University, Portland 97201-3098, USA.; A rat cDNA (rRam-1), which was cloned on the basis that it enables Chinese hamster ovary (CHO) cells to be infected by amphotropic host range murine retroviruses, was recently found to encode a widely expressed Na(+)-phosphate symporter (M. P. Kavanaugh, D. G. Miller, W. Zhang, W. Law, S. L. Kozak, D. Kabat, and A. D.
Determination of human immunodeficiency virus RNA in plasma and cellular viral DNA genotypic zidovudine resistance and viral load during zidovudine-didanosine combination therapy.: J Virol. 1995 Jun;69(6):3510-6. Unique Identifier : AIDSLINE MED/95264440; Holodniy M; Mole L; Margolis D; Moss J; Dong H; Boyer E; Urdea M; Kolberg J; Eastman S; AIDS Research Center, Department of Veterans Affairs Medical; Center, Palo Alto, California, USA.; Eleven human immunodeficiency virus (HIV)-infected subjects on long-term zidovudine (ZDV) therapy had didanosine (ddI) added to their antiretroviral regimen. HIV RNA in plasma was quantitated by branched-DNA signal amplification assay. Peripheral blood mononuclear cell (PBMC) HIV viral DNA was quantitated by PCR. The
Inducible and conditional inhibition of human immunodeficiency virus proviral expression by vesicular stomatitis virus matrix protein.: J Virol. 1995 Jun;69(6):3529-37. Unique Identifier : AIDSLINE MED/95264442; Paik SY; Banerjea AC; Harmison GG; Chen CJ; Schubert M; Laboratory of Molecular Medicine and Neuroscience, National; Institute of Neurological Disorders and Stroke, Bethesda,; Maryland 20892, USA.; Besides its role in viral assembly, the vesicular stomatitis virus (VSV) matrix (M) protein causes cytopathic effects such as cell rounding (D. Blondel, G. G. Harmison, and M. Schubert, J. Virol. 64:1716-1725, 1990). DNA cotransfection assays demonstrated that VSV M protein was able to inhibit the transcription of a r
Comparative analyses of human immunodeficiency virus type 1 (HIV-1) and HIV-2 Vif mutants.: J Virol. 1995 Jun;69(6):3549-53. Unique Identifier : AIDSLINE MED/95264445; Reddy TR; Kraus G; Yamada O; Looney DJ; Suhasini M; Wong-Staal F; Department of Medicine, University of California at San Diego, La; Jolla 92093-0665, USA.; Virion infectivity factor (vif), a gene found in all lentiviruses, plays an essential role in virus replication in certain target cells. We examined the replication competence of the human immunodeficiency virus type 2 (HIV-2) vif mutant in different T-cell lines and primary cells in comparison with that of the HIV-1
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs.: J Virol. 1995 Jun;69(6):3584-96. Unique Identifier : AIDSLINE GENBANK/U23731; Ou SH; Wu F; Harrich D; Garcia-Martinez LF; Gaynor RB; Department of Medicine, University of Texas Southwestern Medical; Center at Dallas 75235, USA.; Human immunodeficiency virus type 1 (HIV-1) gene expression is modulated by both viral and cellular factors. A regulatory element in the HIV-1 long terminal repeat known as TAR, which extends from nucleotides -18 to +80, is critical for the activation of gene expression by the transactivator protein, Tat. RNA transcri
Nucleotide sequence of feline immunodeficiency virus: classification of Japanese isolates into two subtypes which are distinct from non-Japanese subtypes.: J Virol. 1995 Jun;69(6):3639-46. Unique Identifier : AIDSLINE +; Kakinuma S; Motokawa K; Hohdatsu T; Yamamoto JK; Koyama H; Hashimoto H; Department of Virology, Kitasato Institute, Tokyo, Japan.; Seven isolates of feline immunodeficiency virus (FIV), Shizuoka, Yokohama, Sendai-1, Sendai-2, Fukuoka, Aomori-1, and Aomori-2, were isolated from FIV-seropositive domestic cats in Japan , and their proviral DNAs were amplified by PCR. The nucleotide sequences of their env and gag ge
Nascent human immunodeficiency virus type 1 reverse transcription occurs within an enveloped particle.: J Virol. 1995 Jun;69(6):3675-82. Unique Identifier : AIDSLINE MED/95264459; Zhang H; Zhang Y; Spicer T; Henrard D; Poiesz BJ; Department of Medicine, State University of New York Health; Science Center at Syracuse 13210, USA.; Although a small amount of viral DNA has been shown to be enclosed within human immunodeficiency virus type 1 (HIV-1) virions, the majority of full-length viral DNA is formed after this virus infects target cells. Hence, we undertook investigations to identify the physical characteristics of the HIV-1 replication unit
Enhancement of feline immunodeficiency virus infection after immunization with envelope glycoprotein subunit vaccines.: J Virol. 1995 Jun;69(6):3704-11. Unique Identifier : AIDSLINE MED/95264462; Siebelink KH; Tijhaar E; Huisman RC; Huisman W; de Ronde A; Darby IH; Francis MJ; Rimmelzwaan GF; Osterhaus AD; Institute of Virology, Erasmus University Rotterdam, The; Netherlands.; Cats were immunized three times with different recombinant feline immunodeficiency virus (FIV) candidate vaccines. Recombinant vaccinia virus (rVV)-expressed envelope glycoprotein with (vGR657) or without (vGR657 x 15) the cleavage site and an FIV envelope bacterial fusion protein (beta-Galactosidase-Env) were incorpo
Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1.: J Virol. 1995 Jun;69(6):3712-20. Unique Identifier : AIDSLINE MED/95264463; Lusso P; Cocchi F; Balotta C; Markham PD; Louie A; Farci P; Pal R; Gallo RC; Reitz MS Jr; Laboratory of Tumor Cell Biology, National Cancer Institute,; Bethesda, Maryland 20892, USA.; Human immunodeficiency virus type 1 (HIV-1) isolates derived directly from clinical samples are usually unable to grow in cytokine-independent continuous cell lines, thus hindering the study of their biological features and their sensitivity to humoral and cellular protective immunity. To overcome these limitations, w
Analysis of envelope sequence variants suggests multiple mechanisms of mother-to-child transmission of human immunodeficiency virus type 1.: J Virol. 1995 Jun;69(6):3778-88. Unique Identifier : AIDSLINE +; Briant L; Wade CM; Puel J; Brown AJ; Guyader M; Laboratoire de Virologie, Centre Hospitalo-Universitaire Purpan,; Toulouse, France.; In order to elucidate the molecular mechanisms involved in human immunodeficiency virus type 1 (HIV-1) mother-to-child transmission, we have analyzed the genetic variation within the V3 hypervariable domain and flanking regions of the HIV-1 envelope gene in four mother-child transmission pairs. Phylogenetic analysis a
Serotyping of primary human immunodeficiency virus type 1 isolates from diverse geographic locations by flow cytometry.: J Virol. 1995 Jun;69(6):3807-15. Unique Identifier : AIDSLINE MED/95264474; Zolla-Pazner S; O'Leary J; Burda S; Gorny MK; Kim M; Mascola J; McCutchan F; Veterans Affairs Medical Center, New York, New York 10010, USA.; The immunologic relatedness of the various human immunodeficiency virus type 1 (HIV-1) clades was determined with 13 human anti-HIV-1 monoclonal antibodies (MAbs) to six immunogenic regions of the HIV-1 structural proteins. The immunoreactivity of the native, oligomeric viral envelope glycoproteins expressed on the su
Rescue of human immunodeficiency virus type 1 matrix protein mutants by envelope glycoproteins with short cytoplasmic domains.: J Virol. 1995 Jun;69(6):3824-30. Unique Identifier : AIDSLINE MED/95264476; Mammano F; Kondo E; Sodroski J; Bukovsky A; Gottlinger HG; Division of Human Retrovirology, Dana-Farber Cancer Institute,; Boston, Massachusetts 02115, USA.; The matrix (MA) protein of human immunodeficiency virus type 1 (HIV-1) forms the outer protein shell directly underneath the lipid envelope of the virion. The MA protein has a key role in different aspects of virus assembly, including the incorporation of the HIV-1 Env protein complex, which contains a transmembrane g
Domains upstream of the protease (PR) in human immunodeficiency virus type 1 Gag-Pol influence PR autoprocessing.: J Virol. 1995 Jun;69(6):3878-84. Unique Identifier : AIDSLINE MED/95264485; Zybarth G; Carter C; Department of Microbiology, State University of New York at Stony; Brook 11794, USA.; A critical step in the formation of infectious retroviral particles is the activation of the virally encoded protease (PR) and its release from the Gag-Pol precursor polyprotein. To identify factors that influence this step, the maturation of human immunodeficiency virus type 1 PR from various Gag-PR polyproteins was
Human immunodeficiency virus type 1 preintegration complexes containing discontinuous plus strands are competent to integrate in vitro.: J Virol. 1995 Jun;69(6):3938-44. Unique Identifier : AIDSLINE MED/95264498; Miller MD; Wang B; Bushman FD; Infectious Disease Laboratory, Salk Institute for Biological; Studies, La Jolla, California 92037, USA.; Despite intensive study, the mechanism by which many retroviruses complete reverse transcription has remained unclear. Most retroviruses and all lentiviruses fail to synthesize a full-length second strand of the viral cDNA (plus strand) efficiently in infected cells. For human immunodeficiency virus type 1, we find in
Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection.: J Virol. 1995 Jun;69(6):3949-54. Unique Identifier : AIDSLINE MED/95264500; Freed EO; Englund G; Martin MA; Laboratory of Molecular Microbiology, National Institute of; Allergy and Infectious Diseases, Bethesda, Maryland 20892, USA.; The matrix domain of the human immunodeficiency virus type 1 (HIV-1) Gag protein contains a highly basic region near its amino terminus. It has been proposed that this basic domain, in conjunction with the HIV-1 accessory protein Vpr, is responsible for the localization of the HIV-1 preintegration complex to the nucle
[Clinical usefulness of urinary anti HIV antibody test--a large scale study from 11 institutes in Japan]: Rinsho Byori. 1995 Mar;43(3):249-56. Unique Identifier : AIDSLINE MED/95264581; Yoshihara N; Shimada H; Yamazaki O; Kimura T; Oka S; Kumamoto E; Hirose M; Masuda K; Negishi M; Misawa A; AIDS Research Center, National Institute of Health, Shinjuku-ku,; Tokyo.; An enzyme immuno assay kit has been developed to detect anti-HIV antibody in urine. In order to examine the clinical utility of the kit, 1333 urine samples were assayed. These samples consisted of 233 urine samples from HIV infected patients, 472 samples from HIV uninfected patients including 203 samples from patients
Early intrathecal events in rhesus macaques (Macaca mulatta) infected with pathogenic or nonpathogenic molecular clones of simian immunodeficiency virus.: Lab Invest. 1995 May;72(5):547-58. Unique Identifier : AIDSLINE MED/95264703; Smith MO; Heyes MP; Lackner AA; California Regional Primate Research Center, University of; California, Davis, USA.; BACKGROUND: Encephalitis is a common and devastating sequela of HIV infection in humans and of simian immunodeficiency virus (SIV) infection in rhesus macaques. We used the SIV-infected rhesus macaque model to study early intrathecal events in the pathogenesis of lentiviral encephalitis. EXPERIMENTAL DESIGN: To examin
Characterization of hepatic allograft infiltrates in rats pretreated with donor-specific blood transfusion (DST).: J Surg Res. 1995 May;58(5):460-4. Unique Identifier : AIDSLINE MED/95264713; Makino Y; Yamaguchi Y; Goto M; Matsuno K; Takata N; Kikuchi N; Hamaguchi H; Hisama N; Mori K; Ogawa M; Department of Surgery II, Kumamoto University Medical School,; Japan.; A single intravenous injection of 1 ml freshly heparinized donor blood given 7 days prior to transplantation prolonged significantly the survival of subsequent hepatic allografts in fully allogeneic ACI(RT1a)-to-LEW(RT1(1)) rats. The cellular identity of allograft infiltrates was investigated at various times after tr
[Retrovirus: diagnostic tests and their interpretation (II). HIV-2, HTLV-I, and HTLV-II infection]: Med Clin (Barc). 1993 Sep 11;101(7):264-8. Unique Identifier : AIDSLINE MED/95264762; Soriano V; Gutierrez M; Gonzalez-Lahoz J; Servicio de Enfermedades Infecciosas, Instituto de Salud Carlos; III, Madrid.
[Value of blood triglycerides as predictor of HIV progression in intravenous drug addicts (letter)]: Med Clin (Barc). 1993 Sep 11;101(7):277. Unique Identifier : AIDSLINE MED/95264768; Pulido F; Castilla V; Rubio R; Costa JR
[Non-Hodgkin's lymphomas associated with the acquired immunodeficiency syndrome. A multicenter clinical study of 77 cases (see comments)]: Med Clin (Barc). 1995 Apr 8;104(13):481-6. Unique Identifier : AIDSLINE MED/95264771; Rubio R; Pulido F; Pintado V; Diaz-Mediavilla J; Flores E; Serrano M; Alberdi JC; Lopez-Gay D; Verdejo J; Barros C; et al; Grupo Cooperativo SIDA y Tumores de Madrid (Hospital 12 de; Octubre).; BACKGROUND: The aim of the present was to study the prevalence of non Hodgkin s lymphoma (NHL) in AIDS patients as well as the clinicopathologic characteristics, response to treatment and survival. METHODS: From January 1984 to January 1991, 77 patients with NHL associated with AIDS diagnosed in 9 hospitals in Madrid
[Lymphomas in patients with human immunodeficiency virus infection. A bad present, a better future? (editorial; comment)]: Med Clin (Barc). 1995 Apr 8;104(13):500-2. Unique Identifier : AIDSLINE MED/95264774; Ribera Santasusana JM
[The number of patients with HIV infection and tuberculosis is on the increase. A study shows that the majority of them are foreign-born]: Lakartidningen. 1995 May 3;92(18):1926-8. Unique Identifier : AIDSLINE MED/95264808; Hakanson A; Julander I; Ostlund L; Infektionskliniken, Huddinge sjukhus.
Morbidity and mortality from transfusion-transmitted disease in haemophilia [letter; comment]: Lancet. 1995 May 20;345(8960):1309. Unique Identifier : AIDSLINE MED/95264844; Lee CA; Sabin CA; Phillips AN; Elford J; Pasi J
[Recurrent anguilluliasis in a Senegalese infected with human T leukemia virus 1 (HTLV1) (letter)]: Med Trop (Mars). 1994;54(4):375. Unique Identifier : AIDSLINE MED/95264901; Sane M; M'Baye PS; Morel H; Michel P; Talarmin F
Comparing the AIDS and diabetes epidemics [letter; comment]: Med J Aust. 1995 Apr 17;162(8):445, 447. Unique Identifier : AIDSLINE MED/95264960; Welborn TA
Restrictions on HIV-infected health care workers [letter; comment]: Med J Aust. 1995 May 1;162(9):498-9. Unique Identifier : AIDSLINE MED/95264983; Le Leu LA; Jezukaitis PT
AZT in pregnant women with HIV: risks and benefits.: Neonatal Netw. 1995 Mar;14(2):62-3. Unique Identifier : AIDSLINE MED/95265012; Doyle VB
Comparative evaluation of the Premier enzyme immunoassay, micro-immunodiffusion and complement fixation tests for the detection of Histoplasma capsulatum var. capsulatum antibodies.: Mycoses. 1994 Sep-Oct;37(9-10):313-6. Unique Identifier : AIDSLINE MED/95265063; Sekhon AS; Kaufman L; Kobayashi GS; Moledina N; Jalbert M; Notenboom RH; National Centre for Human Mycotic Diseases, University of Alberta; Hospital, Edmonton, Canada.; A total of 178 sera, including 68 from proven cases of histoplasmosis (65 positive for the presence of Histoplasma capsulatum var. capsulatum antibodies and three positive for antigen), 93 from patients with suspected histoplasmosis but with no laboratory evidence of H. capsulatum var. capsulatum infection, 14 from hu
Pulmonary fungal infections in immunocompromised patients: incidence and risk factors.: Mycoses. 1994 Sep-Oct;37(9-10):329-35. Unique Identifier : AIDSLINE MED/95265066; von Eiff M; Roos N; Fegeler W; von Eiff C; Zuhlsdorf M; Glaser J; van de Loo J; Department of Internal Medicine A, University of Munster,; Germany.; In a prospective study, 178 patients with fever > 38.4 degrees C and newly diagnosed pulmonary infiltrates underwent bronchoscopy with bronchoalveolar lavage (BAL), aspiration of bronchial secretions (BS) and, in 71 cases, protected specimen brushing (PSB). In 42/143 immunocompromised patients (haematological malignan
Association between Malassezia furfur colonization and seborrhoeic dermatitis in AIDS patients.: Mycoses. 1994 Sep-Oct;37(9-10):367-70. Unique Identifier : AIDSLINE MED/95265073; Ross S; Richardson MD; Graybill JR; Infectious Diseases Section, Audie L. Murphy Memorial Veterans'; Hospital, San Antonio, Texas 78284, USA.; A total of 180 HIV-positive patients were assessed for seborrhoeic dermatitis (SD) and colonization with Malassezia species. Diseased skin of patients with seborrhoeic dermatitis were sampled selectively for Malassezia. In patients without SD, uninvolved skin was sampled. The prevalence of SD was 19%. Of the 34 SD pat
AIDS pathology unknown [news]: Nature. 1995 May 18;375(6528):167. Unique Identifier : AIDSLINE MED/95265077
Agency halts HIV survey in dispute over newborn data [news]: Nature. 1995 May 18;375(6528):169. Unique Identifier : AIDSLINE MED/95265080; Touchette N
HIV results in the frame. Results confirmed [letter; comment]: Nature. 1995 May 18;375(6528):193. Unique Identifier : AIDSLINE MED/95265088; Nowak MA; Bonhoeffer S; Loveday C; Balfe P; Semple M; Kaye S; Tenant-Flowers M; Tedder R
HIV results in the frame. CD4+ cell turnover [letter; comment]: Nature. 1995 May 18;375(6528):193-4; discussion 198. Unique Identifier : AIDSLINE MED/95265089; Mosier DE
HIV results in the frame. CD4+ cell turnover [letter; comment]: Nature. 1995 May 18;375(6528):194; discussion 198. Unique Identifier : AIDSLINE MED/95265090; Sprent J; Tough D
HIV results in the frame. CD4+ cell turnover [letter; comment]: Nature. 1995 May 18;375(6528):194-5; discussion 198. Unique Identifier : AIDSLINE MED/95265091; Dimitrov DS; Martin MA
HIV results in the frame. Antiviral therapy [letter; comment]: Nature. 1995 May 18;375(6528):195; discussion 198. Unique Identifier : AIDSLINE MED/95265092; Phillips AN; Sabin CA; Mocroft A; Janossy G
HIV results in the frame. Other approaches [letter; comment]: Nature. 1995 May 18;375(6528):195-6; discussion 198. Unique Identifier : AIDSLINE MED/95265093; Bukrinsky M; Manogue K; Cerami A
HIV results in the frame. Paradox remains [letter; comment]: Nature. 1995 May 18;375(6528):196; discussion 198. Unique Identifier : AIDSLINE MED/95265094; Ascher MS; Sheppard HW; Anderson RW; Krowka JF; Bremermann HJ
HIV results in the frame. Paradox remains [letter]: Nature. 1995 May 18;375(6528):196-7; discussion 198. Unique Identifier : AIDSLINE MED/95265095; Lai S; Page JB; Lai H
HIV results in the frame. HIV an illusion [letter; comment]: Nature. 1995 May 18;375(6528):197; discussion 198. Unique Identifier : AIDSLINE MED/95265097; Duesberg P; Bialy H
HIV results in the frame. Toxic shock [letter; comment]: Nature. 1995 May 18;375(6528):197-8; discussion 198. Unique Identifier : AIDSLINE MED/95265098; Michie C
HIV results in the frame. Cyclosporin A [letter; comment]: Nature. 1995 May 18;375(6528):198; discussion 198. Unique Identifier : AIDSLINE MED/95265099; Weber J; Galpin S
Primary CNS lymphoma [letter; comment]: Neurology. 1995 May;45(5):1031-2. Unique Identifier : AIDSLINE MED/95265178; Chamberlain MC
Making the extra effort.: Nursing. 1995 May;25(5):65. Unique Identifier : AIDSLINE MED/95265339; Baker W Jr
Anterior uveitis and diabetes mellitus: immunological study.: Ophthalmologica. 1995;209(2):53-5. Unique Identifier : AIDSLINE MED/95265442; Castagna I; Fama F; Salmeri G; Institute of Ophthalmology, University of Messina, Italy.; The association between anterior uveitis (AU) and diabetes mellitus (DM) has always been known. The purpose of this study was to estimate the incidence of this association and to consider a possible role of the cell-mediated immune system. During the years 1989-1992, 196 diabetics (66 patients affected by type I DM an
[The use of results of scientific nutrition research in clinical practice]: Orv Hetil. 1995 May 7;136(19):979-83. Unique Identifier : AIDSLINE MED/95265460; Biro G; Orszagos Elelmezes- es Taplalkozastudomanyi Intezet,; Budapest.; Author surveys clinically relevant results of recent years nutritional researches. More and more details of the etiological bases of the diet-disease relation are revealed by molecular biology, e.g. the genetic background of link between fat intake and cardiovascular diseases, the metabolism of fatty acids. The resul
State tackles HIV/AIDS with prevention plan.: Pa Med. 1995 Apr;98(4):14-5. Unique Identifier : AIDSLINE MED/95265465
Tuberculosis in children younger than five years old: New York City.: Pediatr Infect Dis J. 1995 Feb;14(2):112-7. Unique Identifier : AIDSLINE MED/95265490; Driver CR; Luallen JJ; Good WE; Valway SE; Frieden TR; Onorato IM; Division of Tuberculosis Elimination, Centers for Disease Control; and Prevention, Atlanta, GA, USA.; We examined medical and health department records for children
Antibody responses to Haemophilus influenzae type b and Streptococcus pneumoniae vaccines in children with human immunodeficiency virus infection.: Pediatr Infect Dis J. 1995 Feb;14(2):129-35. Unique Identifier : AIDSLINE MED/95265493; Gibb D; Spoulou V; Giacomelli A; Griffiths H; Masters J; Misbah S; Nokes L; Pagliaro A; Giaquinto C; Kroll S; et al; Institute of Child Health, London, United Kingdom.; Antibody responses to Haemophilus influenzae type b (Hib) conjugate (ActHIB; Pasteur Merieux) and pneumococcal (Pneumovax II; Morson) vaccines were measured in 56 infected children (VI) and 44 uninfected children (U) older than 18 months of age, born to human immunodeficiency virus-positive mothers. Preimmunization, 2
Decline of measles antibody titers after immunization in human immunodeficiency virus-infected children.: Pediatr Infect Dis J. 1995 Feb;14(2):149-51. Unique Identifier : AIDSLINE MED/95265497; al-Attar I; Reisman J; Muehlmann M; McIntosh K; Bureau of Family and Community Health, Massachusetts Department; of Public Health, Boston, USA.
Perinatal human immunodeficiency virus infection and congenital Chagas' disease.: Pediatr Infect Dis J. 1995 Feb;14(2):161-2. Unique Identifier : AIDSLINE MED/95265505; Freilij H; Altcheh J; Muchinik G; Parasitologia, Hospital de Ninos, Ricardo Gutierrez, Buenos; Aires, Argentina.
Intestinal and extraintestinal Isospora belli infection in an AIDS patient. A second case report.: Pathol Res Pract. 1994 Nov;190(11):1089-93; discussion 1094. Unique Identifier : AIDSLINE MED/95265543; Michiels JF; Hofman P; Bernard E; Saint Paul MC; Boissy C; Mondain V; LeFichoux Y; Loubiere R; Laboratoire d'Anatomie Pathologique, Centre Hospitalier, France.; A 30-year-old black female, from Burkina Faso , had AIDS in 1990. She died in March 1993 following a cachexia secondary to a chronic intestinal isosporiasis . The autopsy revealed a massive parasitic infection by I. belli of the small in
Intestinal cytomegalovirus infection: a diagnostic problem in an HIV-positive patient [letter]: Postgrad Med J. 1995 Mar;71(833):187. Unique Identifier : AIDSLINE MED/95265586; Laing RB; Welsby PD
[Infectious complications of implantable catheters in HIV infected patients. Retrospective study of 46 patients]: Presse Med. 1995 Mar 11;24(10):474-8. Unique Identifier : AIDSLINE MED/95265604; Gisselbrecht M; Eliaszewicz M; Pialoux G; Janssen B; Fleury J; Gonzalez G; Feuillie V; Dupont B; Service de Maladies infectieuses, Hopital de l'Institut Pasteur,; Paris.; OBJECTIVES: Investigate the rate of infection in HIV positive patients with an implantable venous access device. METHODS: Forty-six totally implantable venous access devices (port-a-cath, PAC) were inserted in 46 HIV infected patients between January 1990 and May 1992. We analyzed the rate of infectious complications
[Rectal Kaposi sarcoma in AIDS treated by photocoagulation (letter)]: Presse Med. 1995 Mar 4;24(9):460. Unique Identifier : AIDSLINE MED/95265625; Fremond L; Vandromme L; Barhoum G; Devulder F; Remy G
The Croonian Lecture, 1994. Populations, infectious disease and immunity: a very nonlinear world.: Philos Trans R Soc Lond B Biol Sci. 1994 Dec 29;346(1318):457-505. Unique Identifier : AIDSLINE MED/95265650; Anderson RM; Department of Zoology, University of Oxford, U.K.; The interaction between the variables that determine the typical course of infection in an individual patient and those that determine transmission in communities of people is often complex and very nonlinear in form. Mathematical models of infection and immunity are used to study the interaction in a wide variety of
Advances in hepatitis D virus biology and disease.: Prog Liver Dis. 1994;12:157-75. Unique Identifier : AIDSLINE MED/95265677; Smedile A; Rizzetto M; Gerin JL; Department of Gastroenterology, Ospedale Molinette, Italy.; Studies over the last decade have defined the natural history and diagnostic features of hepatitis D. Whereas hepatitis D encompasses a wide spectrum of clinical manifestations, patients usually have severe and progressive liver disease. In areas of high endemicity such as Italy , he
[The epidemiological surveillance of AIDS in Panama]: Rev Med Panama. 1994 Sep;19(3):186-92. Unique Identifier : AIDSLINE MED/95265708; Guerrero Delgado GA; Penna Franco MI; The authors report the results of the epidemiological surveillance of AIDS in Panama and they detail the incidence according to sex, place of residence, the mode of contagion and mortality. They point out that in children less than
Immunotherapy with Mycobacterium vaccae as an addition to chemotherapy for the treatment of pulmonary tuberculosis under difficult conditions in Africa.: Respir Med. 1995 Mar;89(3):199-207. Unique Identifier : AIDSLINE MED/95265718; Onyebujoh PC; Abdulmumini T; Robinson S; Rook GA; Stanford JL; Department of Medical Microbiology, University College London; Medical School.; A study to assess the impact of immunotherapy with Mycobacterium vaccae on the treatment of pulmonary tuberculosis was conducted under existing conditions in Kano, a large city in Northern Nigeria . Whilst it did not quite meet all the criteria of a well-controlled randomized or do
[The surgical management of pneumothorax in patients with AIDS]: Rev Mal Respir. 1995;12(2):151-60. Unique Identifier : AIDSLINE MED/95265746; Riquet M; Le Pimpec-Barthes F; Debrosse D; Houel R; Hubsch JP; Manac'h D; Saab M; Debesse B; Service de Chirurgie Thoracique, Hopital Laennec, Paris.; The occurrence of a pneumothorax occurring as a complication of AIDS is a poor prognostic sign. We have undertaken a review of 26 patients admitted to hospital for a pneumothorax of whom 25 were admitted for therapy: five resolved under simple drainage; twenty required a pleurodesis which was performed on thirteen und
[AIDS: a model for the study of atopy? (see comments)]: Rev Mal Respir. 1995;12(2):177-83. Unique Identifier : AIDSLINE MED/95265753; Magnan A; Vervloet D; Service de Pneumo-Allergologie, Hopital Sainte-Marguerite,; Marseille.; The drug intolerance and allergic manifestations linked to infection with the Human Immunodeficiency Virus (HIV) are often misunderstood. However, in the light of recent advances in immunopathology, these manifestations perhaps give an indication as to more general mechanisms of allergy. Drug intolerance is frequent d
[Drug allergy and atopy: lessons from AIDS (editorial; comment)]: Rev Mal Respir. 1995;12(2):77-8. Unique Identifier : AIDSLINE MED/95265756; Polla BS
[Percutaneous pericardiotomy: nonsurgical treatment of severe or recurrent pericardial effusion]: Rev Med Liege. 1995 Apr;50(4):175-7. Unique Identifier : AIDSLINE MED/95265794; Bertrand O; Legrand V; Kulbertus H; Service de Cardiologie, Universite de Liege.
[AIDS, developing countries and ethnopsychiatry]: Rev Med Liege. 1995 Apr;50(4):182-8. Unique Identifier : AIDSLINE MED/95265796; Ehrhardt N; Defourny J; Bertrand J; l'Hopital de Jour universitaire La Cle, Departement de; Medecine psychosomatique, Universite de Liege.
Bacteremia in HIV-positive and AIDS patients: incidence, species distribution, risk-factors, outcome, and influence of long-term prophylactic antibiotic treatment.: Scand J Infect Dis. 1994;26(6):635-42. Unique Identifier : AIDSLINE MED/95265895; Meyer CN; Skinhoj P; Prag J; Department of Infectious Diseases, Rigshospitalet, Copenhagen,; Denmark.; From a cohort of 837 adult, mainly homosexual HIV-infected patients, 76 bacteremic/fungemic episodes were identified in 63 patients over a 5-year period. Compared with an age-matched reference population with an incidence of 10.3 bacteremias/10,000 person-years, the incidence was 170 among pre-AIDS (p
Natural history of asymptomatic and symptomatic pneumocystis carinii infection in HIV infected patients.: Scand J Infect Dis. 1994;26(6):643-51. Unique Identifier : AIDSLINE MED/95265896; Elvin K; Lidman C; Tynell E; Linder E; Bjorkman A; Department of Microbiology, Karolinska Institute, Swedish; Institute for Infectious Disease Control, Stockholm.; The natural appearance of Pneumocystis carinii in induced sputum samples was studied in 60 HIV-infected patients with severe immunodeficiency and without a history of P. carinii pneumonia (PCP). The patients were prospectively evaluated for occurrence of P. carinii in induced sputum samples, PCP diagnosis and CD4+ cel
Pseudo-outbreak of pseudomonas aeruginosa in HIV-infected patients undergoing fiberoptic bronchoscopy.: Scand J Infect Dis. 1994;26(6):653-7. Unique Identifier : AIDSLINE MED/95265897; Kolmos HJ; Lerche A; Kristoffersen K; Rosdahl VT; Department of Clinical Microbiology, Hvidovre Hospital,; University of Copenhagen, Denmark.; Pseudomonas aeruginosa was isolated from bronchoalveolar lavage fluid from 8 consecutive patients undergoing bronchoscopy at an infectious diseases unit. None of the patients developed signs of respiratory tract infection that could be ascribed to the organism. The source of contamination was the suction channels of 2
Long-term remission of Kaposi's sarcoma following foscarnet treatment in HIV-infected patients.: Scand J Infect Dis. 1994;26(6):749-52. Unique Identifier : AIDSLINE MED/95265910; Morfeldt L; Torssander J; Division of Infectious Diseases, Karolinska Institute, Danderyd; Hospital, Sweden.; Five patients with HIV-associated Kaposi s sarcoma (epidemic KS) were treated with foscarnet 180 mg/kg/day i.v. for 10 days. Four of them suffered from severe immunodeficiency with CD4 cell counts below 30 x 10(6)/l. Three of the patients went into long-term remission of KS. One patient was free of relapse for 12 mont
Isolated kidney localization of invasive Aspergillosis in a patient with AIDS.: Scand J Infect Dis. 1994;26(6):767-70. Unique Identifier : AIDSLINE MED/95265916; Viale P; Di Matteo A; Sisti M; Voltolini F; Paties C; Alberici F; Division of Infectious Diseases, Ospedale Civile di Piacenza,; Italy.; Although the importance of Aspergillus in AIDS is now increasing, extra-pulmonary disease is still an unusual event, especially when a single localization occurs. A case of isolated renal aspergilloma in an AIDS patient is described. At onset, no recognized risk factors were present in our patient. An early surgical a
Prediction of attitudes towards restrictive AIDS policies: a structural equation modelling approach.: Soc Sci Med. 1995 Mar;40(5):711-8. Unique Identifier : AIDSLINE MED/95266017; Kraft P; Rise J; Department of Health and Society, National Institute of Public; Health, Oslo, Norway.; The purpose of the study was to test a prehypothesized structural equation model of predictors of attitudes towards restrictive AIDS policies. It was assumed that such attitudes ae under influence of both cognitive processes and more general attitudinal structures. The hypothesized model was tested against empirical d
The relationship between changes in sexual support and adjustment to AIDS in gay males.: Soc Work Health Care. 1995;20(3):37-49. Unique Identifier : AIDSLINE MED/95266053; Rodgers AY; University of Pittsburgh, School of Social Work, PA, USA.; The present study examined how changes in social support and the maintenance of a specific level of social support affected individuals adjustment to AIDS. Results indicated that individuals who perceived that they had an increase in social support and persons who had a stable, high level of support reported better a
New Leishmania (Leishmania) infantum zymodemes responsible for visceral leishmaniasis in patients co-infected with HIV in Spain [published erratum appears in Trans R Soc Trop Med Hyg 1995 Jul-Aug;(89)4:369]: Trans R Soc Trop Med Hyg. 1995 Jan-Feb;89(1):33. Unique Identifier : AIDSLINE MED/95266117; Jimenez MI; Laguna F; de la Torre F; Solis F; Pratlong F; Alvar J; Laboratorio Nacional de Referencia de Leishmaniasis.
Tuberculin sensitivity and HIV-1 status of patients attending a sexually transmitted diseases clinic in Lusaka, Zambia: a cross-sectional study.: Trans R Soc Trop Med Hyg. 1995 Jan-Feb;89(1):37-40. Unique Identifier : AIDSLINE MED/95266120; Duncan LE; Elliott AM; Hayes RJ; Hira SK; Tembo G; Mumba GT; Ebrahim SH; Quigley M; Pobee JO; McAdam KP; School of Medicine, University of Zambia, Lusaka.; A cross-sectional study to estimate the prevalence of latent tuberculosis (TB) in a group of Zambians at high risk of human immunodeficiency virus type 1 (HIV-1) infection and to examine the effect of HIV-1 infection on the tuberculin response was conducted in the University Teaching Hospital in Lusaka, Zambia during
The impact of human immunodeficiency virus on mortality of patients treated for tuberculosis in a cohort study in Zambia.: Trans R Soc Trop Med Hyg. 1995 Jan-Feb;89(1):78-82. Unique Identifier : AIDSLINE MED/95266133; Elliott AM; Halwiindi B; Hayes RJ; Luo N; Mwinga AG; Tembo G; Machiels L; Steenbergen G; Pobee JO; Nunn P; et al; School of Medicine, University of Zambia, Lusaka.; We have examined the impact of human immunodeficiency virus (HIV) on mortality of patients treated for tuberculosis in a prospective study in Lusaka, Zambia . Patients with sputum smear-positive, miliary, or meningeal tuberculosis were prescribed 2 months daily streptomycin, thiace
Testing for enzootic bovine leukosis [letter; comment]: Vet Rec. 1995 Feb 11;136(6):156. Unique Identifier : AIDSLINE MED/95266224; Gibson LA
The distribution of lymphocyte subpopulations in normal and acanthotic ovine skin.: Vet Immunol Immunopathol. 1995 Jan;44(2):151-67. Unique Identifier : AIDSLINE MED/95266229; Gorrell MD; Townsend WL; Ladds PW; Centre for Animal Biotechnology, University of Melbourne,; Parkville, Vic., Australia.; The prevalence and distribution of lymphocyte subpopulations in normal and acanthotic ovine skin were investigated using monoclonal antibody immunocytochemistry. CD8+ cells were predominant in the epidermis of both normal and acanthotic skin, but were CD8+ cells, CD4+ cells and T19+ cells infrequent in normal epidermi
Proliferating cell nuclear antigen expression in sheep infected with bovine leukemia virus.: Vet Immunol Immunopathol. 1995 Feb;44(3-4):211-22. Unique Identifier : AIDSLINE MED/95266233; Hailata N; Johnson R; al-Bagdadi F; Hanash S; Department of Clinical Veterinary Medical Sciences, Faculty of; Veterinary Medicine, Jordan University of Science and Technology,; Irbid.; Proliferating cell nuclear antigen (PCNA) or cyclin (C), a major nuclear protein, has been shown to be associated with human leukemia and malignancies. PCNA protein was quantitated in this study, in lymphocytes from bovine leukemia virus (BLV) infected and non-infected sheep, using two-dimensional polyacrylamide gel e
The C/EBP site in the feline immunodeficiency virus (FIV) long terminal repeat (LTR) is necessary for its efficient replication and is also involved in the inhibition of FIV LTR-directed gene expression by pseudorabies virus ICP4.: Virology. 1995 Apr 20;208(2):492-9. Unique Identifier : AIDSLINE MED/95266255; Kawaguchi Y; Tomonaga K; Maeda K; Ono M; Miyazawa T; Kohmoto M; Tohya Y; Mikami T; Department of Veterinary Microbiology, Faculty of Agriculture,; University of Tokyo, Japan.; We investigated effects of site-specific mutation of the putative C/EBP binding site in the feline immunodeficiency virus (FIV) long terminal repeat (LTR) on the basal promoter activity in Crandell feline kidney (CRFK) cells and on replication efficiency in CRFK cells and a T-lymphoblastoid cell line, MYA-1 cells. Mut
Protection against EHV-1 challenge infection in the murine model after vaccination with various formulations of recombinant glycoprotein gp14 (gB).: Virology. 1995 Apr 20;208(2):500-10. Unique Identifier : AIDSLINE MED/95266256; Osterrieder N; Wagner R; Brandmuller C; Schmidt P; Wolf H; Kaaden OR; Institute for Medical Microbiology, Infectious and Epidemic; Diseases, Ludwig-Maximilians-University Munich, Germany.; Four formulations of the equine herpesvirus type 1 (EHV-1) glycoprotein gp 14 (gB), were tested for their ability to protect mice against intranasal (inas) EHV-1 challenge infection. The preparations tested included (i) a truncated gp14 produced in Escherichia coli or (ii) a truncated gp14 expressed in insect cells by
HIV-induced TNF-alpha regulates arachidonic acid and PGE2 release from HIV-infected mononuclear phagocytes.: Virology. 1995 Apr 20;208(2):590-600. Unique Identifier : AIDSLINE MED/95266265; Nokta MA; Hassan MI; Loesch KA; Pollard RB; Department of Internal Medicine, University of Texas Medical; Branch, Galveston 77555-0882, USA.; Arachidonic acid (AA) has been shown to interact with transmembrane signaling pathways involved in T-cell activation. The latter have been shown to be impaired in lymphocytes obtained from HIV-infected patients. In the present study, AA and its metabolite, PGE2, released from differentiating human mononuclear phagocyt
A highly defective HIV-1 group O provirus: evidence for the role of local sequence determinants in G-->A hypermutation during negative-strand viral DNA synthesis.: Virology. 1995 Apr 20;208(2):601-9. Unique Identifier : AIDSLINE MED/95266266; Borman AM; Quillent C; Charneau P; Kean KM; Clavel F; Oncologie Virale (INSERM URA 1157), Departement Sida et; Retrovirus, Institut Pasteur, Paris, France.; The sequence of 2350 nucleotides in the env and IN regions of a group O HIV-1 genome which is hypermutated throughout its entirety was compared to the equivalent sequence of a nonhypermutated genome from the same isolate. Almost 30% of G residues were affected by G-->A transitions. As previously reported, transitions
The tempo and mode of SIV quasispecies development in vivo calls for massive viral replication and clearance.: Virology. 1995 Apr 20;208(2):644-52. Unique Identifier : AIDSLINE MED/95266270; Pelletier E; Saurin W; Cheynier R; Letvin NL; Wain-Hobson S; Unite de Retrovirologie Moleculaire, CNRS UAD 1444, Institut; Pasteur, Paris.; Simian immunodeficiency virus (SIV) quasispecies development was followed in four monkeys (Macacca fascicularis) infected by intramuscular inoculation of phage lambda-SIVmac239 DNA. Rooted phylogenetic trees were reconstructed and used to interpret the data. The rate of fixation of base substitutions varied within and
Induction of Sp1 phosphorylation and NF-kappa B-independent HIV promoter domain activity in T lymphocytes stimulated by okadaic acid.: Virology. 1995 Apr 20;208(2):753-61. Unique Identifier : AIDSLINE MED/95266282; Vlach J; Garcia A; Jacque JM; Rodriguez MS; Michelson S; Virelizier JL; Unite d'Immunologie Virale, Institut Pasteur, Paris, France.; In contrast to the purely enhancer-dependent effect of cytokines such as TNF on the activity of the HIV regulatory region (LTR), we observed that okadaic acid (OKA) activates HIV transcription through both the enhancer, responding to the factor NF-kappa B, and the promoter domain of the LTR. The inducibility of HIV LT
Human immunodeficiency virus type 1 envelope glycoprotein-specific cytotoxic T lymphocytes in simian-human immunodeficiency virus-infected rhesus monkeys.: Virology. 1995 Apr 20;208(2):770-5. Unique Identifier : AIDSLINE MED/95266284; Voss G; Li J; Manson K; Wyand M; Sodroski J; Letvin NL; Harvard Medical School, Beth Israel Hospital, Boston,; Massachusetts 02215, USA.; Because of the importance of the envelope glycoprotein (Env) in determining the pathogenicity of HIV-1 and the importance of the immune response to Env in controlling virus spread, attempts are being made to study HIV-1 Env-directed immunity in primate models. To date HIV-1 Env-specific effector T lymphocyte responses
Susceptibility of human bone marrow stromal cells to human immunodeficiency virus (HIV).: Virology. 1995 Apr 20;208(2):779-83. Unique Identifier : AIDSLINE MED/95266286; Canque B; Marandin A; Rosenzwajg M; Louache F; Vainchenker W; Gluckman JC; Unite de Recherche Associee 1463, Centre National de la; Recherche Scientifique, Paris, France.; It is not known whether impaired hematopoiesis noted during human immunodeficiency virus (HIV) infection results from infection of stem/progenitor cells or of cells of the bone marrow microenvironment. Normal adherent primary stromal layers were exposed to HIV to determine which of this mixture of endothelial cells, f
Inhibition of wild-type HIV-1 virus production by a matrix deficient Gag mutant.: Virology. 1995 Apr 20;208(2):808-11. Unique Identifier : AIDSLINE MED/95266291; Lee PP; Linial ML; Division of Basic Sciences, Fred Hutchinson Cancer Research; Center, Seattle, Washington 98104, USA.; Previous studies have shown that certain HIV-1 Gag mutants can interfere with the production of infectious HIV-1 when coexpressed with wild-type virus. In this paper, we studied two mutants of HIV-1 for their ability to interfere with the production of wild-type virus. Both mutants lack the entire matrix domain of gag
Enhanced human T-cell lymphotropic virus type I expression following induction of the cellular stress response.: Virology. 1995 Apr 20;208(2):816-20. Unique Identifier : AIDSLINE MED/95266293; Andrews JM; Oglesbee MJ; Trevino AV; Guyot DJ; Newbound GC; Lairmore MD; Department of Veterinary Biosciences, Ohio State University,; Columbus 43210.; Human T-cell lymphotropic virus type I (HTLV-I) infection is typically associated with long incubation periods between virus exposure and disease manifestation. Although viral protein expression is considered to play an important role in the pathogenesis of HTLV-I-associated diseases, limited information is known rega
Biological and molecular characterization of subtype D, G, and A/D recombinant HIV-1 transmissions in Sweden.: Virology. 1995 May 10;209(1):136-46. Unique Identifier : AIDSLINE GENBANK/L40763; Leitner T; Escanilla D; Marquina S; Wahlberg J; Brostrom C; Hansson HB; Uhlen M; Albert J; Department of Clinical Virology, Swedish Institute for Infectious; Disease Control/Karolinska Institute, Stockholm.; HIV-1 can be subdivided into at least nine genetic subtypes (A through H and O), but in Europe and the United States there is an almost complete dominance of subtype B. In this study three Swedish HIV-1 transmission chains of subtypes other than subtype B have been biologically and mol
Use of DNAs expressing HIV-1 Env and noninfectious HIV-1 particles to raise antibody responses in mice.: Virology. 1995 May 10;209(1):147-54. Unique Identifier : AIDSLINE MED/95266301; Lu S; Santoro JC; Fuller DH; Haynes JR; Robinson HL; Department of Pathology, University of Massachusetts Medical; Center, Worcester 01655, USA.; Two DNA constructs encoding portions of the human immunodeficiency virus type-1 (HIV-1) genome have been used to raise antibody responses in BABL/c mice. One DNA (pNL4-3.env) expresses the natural form of the envelope glycoprotein (Env) of HIV-1-NL4-3 (NL4-3). The second (pNL4-3.dpol) produces noninfectious NL4-3 part
The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution.: Virology. 1995 May 10;209(1):29-51. Unique Identifier : AIDSLINE MED/95266321; Gompels UA; Nicholas J; Lawrence G; Jones M; Thomson BJ; Martin ME; Efstathiou S; Craxton M; Macaulay HA; Department of Clinical Sciences, London School of Hygiene and; Tropical Medicine, University of London, United Kingdom.; The complete DNA sequence was determined for strain U1102 of human herpesvirus-6, a CD4+ T-lymphotropic virus with disease associations in immunodeficient settings and a possible complicating factor in AIDS. The genome is 159,321 bp in size, has a base composition of 43% G + C, and contains 119 open reading frames. Th
Increased chemiluminescence of whole blood and normal T-lymphocyte subsets in severe nodular acne and acne fulminans.: Acta Derm Venereol. 1995 Jan;75(1):1-5. Unique Identifier : AIDSLINE MED/95266366; Karvonen SL; Rasanen L; Soppi E; Hyoty H; Lehtinen M; Reunala T; Department of Dermatology, University Hospital of Oulu, Finland.; To investigate the inflammatory and immunological aspects of severe acne, we examined the luminol-enhanced chemiluminescence of whole blood, T-cell subsets and natural killer cell functions in 11 patients with severe nodular acne and 4 patients with acne fulminans. In patients with severe nodular acne, the active phas
Multidrug-resistant tuberculosis.: Adv Intern Med. 1995;40:155-96. Unique Identifier : AIDSLINE MED/95266488; Ellner JJ; Division of Infectious Diseases, University Hospitals of; Cleveland, Ohio, USA.
Gastrointestinal manifestations of human immunodeficiency virus infection.: Adv Intern Med. 1995;40:197-242. Unique Identifier : AIDSLINE MED/95266489; Kotler DP; Department of Medicine, St. Luke's-Roosevelt Hospital Center,; College of Physicians and Surgeons, Columbia University, New; York, New York, USA.
Disappearance of uremia due to heroin-associated nephropathy.: Am J Kidney Dis. 1995 May;25(5):689-93. Unique Identifier : AIDSLINE MED/95266566; Friedman EA; Tao TK; Department of Medicine, State University of New York, Health; Science Center at Brooklyn 11203, USA.; Heroin-associated nephropathy (HAN), a complication of intravenous heroin abuse, was initially recognized at Kings County Hospital in Brooklyn, NY, in the early 1970s. Our recent experience indicates that after a steady incidence of new cases of HAN throughout the mid-1980s, a sharp decrease in incidence of new cases
CD1+ cells in mothers of stillborn infants with neural tube defects.: Am J Med Genet. 1995 Mar 13;56(1):60-1. Unique Identifier : AIDSLINE MED/95266635; Seniz FN; Muftuoglu E; Batun MS; Say B; Department of Pediatrics, University of Dicle, Diyarbakir,; Turkey.; In healthy individuals, CD1+ cells are found in thymic- tissue, but not in peripheral blood. The thymus, as a key organ of the neuroendocrine system, frequently shows gross abnormalities in infants with neural tube defects. In order to study the immunologic significance of fetal thymic findings, maternal T-lymphocyte
Evidence of apoptotic cell death in HIV encephalitis [see comments]: Am J Pathol. 1995 May;146(5):1121-30. Unique Identifier : AIDSLINE MED/95266656; Petito CK; Roberts B; Department of Pathology, University of Miami School of Medicine,; Jackson Memorial Hospital, Florida, USA.; The mechanism of cell death in the brains of patients with acquired immune deficiency syndrome was examined in 15 cases, 8 of whom had human immunodeficiency virus (HIV) encephalitis, and in 8 control cases. Postmortem formalin-fixed, paraffin-embedded sections were prepared for routine histology and immunohistochemis
Immunocytochemical study of CD45 T cell isoforms in inflammatory myopathies.: Am J Pathol. 1995 May;146(5):1178-87. Unique Identifier : AIDSLINE MED/95266662; De Bleecker JL; Engel AG; Neuromuscular Research Laboratory, Mayo Clinic, Rochester, MN; 55905, USA.; The CD45RO and CD45RA antigens subdivide the CD8+ and the CD4+ T cells into primed memory cells and unprimed virgin T cells, respectively. To assess the relative abundance of the CD8+ and the CD4+ T cells expressing the two CD45 isoforms in the major inflammatory myopathies, we immunophenotyped T cells in muscle speci
[Cytomegalovirus pneumopathy in AIDS: a difficult diagnosis (letter)]: Ann Biol Clin (Paris). 1994;52(11):785-6. Unique Identifier : AIDSLINE MED/95266743; Durand B; Doyen C; Sotta C; Guibaud S; Cotte L; Trepo C; Chomel JJ
[Bacillary angiomatosis related to Rochalimaea quintana. Anatomoclinical and ultrastructural study of cutaneous localizations in AIDS]: Arch Anat Cytol Pathol. 1994;42(6):289-96. Unique Identifier : AIDSLINE MED/95266870; Bost F; Brion JP; Peoc'h M; Pinel N; Recule C; Le Marc'hadour F; Pasquier D; Micoud M; Pasquier B; Service d'Anatomie Pathologique, CHU, Hopital Albert-Michallon,; Grenoble.; We report a case of bacillary angiomatosis in a 53-year-old homosexual man with acquired immunodeficiency syndrome (AIDS). Pathological and bacteriological studies of cutaneous nodules led to the identification of a rickettsia: Rochalimaea quintana. This observation prompted
[Intramedullary localization of a primary cerebral lymphoma in AIDS]: Arch Anat Cytol Pathol. 1994;42(6):297-303. Unique Identifier : AIDSLINE MED/95266871; Chretien F; Flament-Saillour M; Paraire F; Polivka M; de Truchis P; Mikol J; Durigon M; Gray F; Service d'Anatomie Pathologique et de Medecine Legale, Hopital; Raymond Poincare, Garches.; A 36 years-old male with AIDS, presented with left hemiparesis revealing a right parietal tumour. Stereotactic biopsy demonstrated a malignant non-Hodgkin s lymphoma . His condition partially improved following radiotherapy and chemotherapy. Three months later he was re-admitted wit
Mycobacterium tuberculosis infection in pregnant and nonpregnant women infected with HIV in the Women and Infants Transmission Study.: Arch Intern Med. 1995 May 22;155(10):1066-72. Unique Identifier : AIDSLINE MED/95266923; Mofenson LM; Rodriguez EM; Hershow R; Fox HE; Landesman S; Tuomala R; Diaz C; Daniels E; Brambilla D; National Institutes of Health, Rockville, Md, USA.; BACKGROUND: Prevalence of Mycobacterium tuberculosis (TB) infection and anergy were evaluated in a cohort of pregnant and nonpregnant women infected with the human immunodeficiency virus who were enrolled in a prospective natural history study (the Women and Infants Transmission Study) conducted in New York, NY; Bosto
Molecular mimicry between the rabies virus and human immunodeficiency virus [letter; comment]: Arch Pathol Lab Med. 1995 May;119(5):391, 393. Unique Identifier : AIDSLINE MED/95266936; Bracci L; Neri P
The presence of Enterocytozoon bieneusi spores in the lamina propria of small bowel biopsies with no evidence of disseminated microsporidiosis. Enteric Opportunistic Infections Working Group.: Arch Pathol Lab Med. 1995 May;119(5):424-8. Unique Identifier : AIDSLINE MED/95266943; Schwartz DA; Abou-Elella A; Wilcox CM; Gorelkin L; Visvesvara GS; Thompson SE 3rd; Weber R; Bryan RT; Department of Pathology, Emory University School of Medicine,; Atlanta, GA, USA.; Enterocytozoon bieneusi is the most frequently reported microsporidial infection of humans. In patients with the acquired immunodeficiency syndrome, Enterocytozoon infects the lining epithelial cells of the small intestine, hepatobiliary tract, and gallbladder. Because Enterocytozoon has been thought to be limited to
Multilocular thymic cyst. A novel thymic lesion associated with human immunodeficiency virus infection.: Arch Pathol Lab Med. 1995 May;119(5):467-70. Unique Identifier : AIDSLINE MED/95266952; Mishalani SH; Lones MA; Said JW; Department of Pathology, Cedars-Sinai Medical Center, Los; Angeles, CA 90048, USA.; Thymic involvement is an important feature of human immunodeficiency virus-related disease in the pediatric population. The most common lesions are thymic involution or atrophy, thymitis (thymic lymphoid hyperplasia), and dysinvolution with loss of Hassall s corpuscles. We report a case of an unusual form of thymic en
Inhibition of human immunodeficiency virus type-1 integrase by curcumin.: Biochem Pharmacol. 1995 Apr 18;49(8):1165-70. Unique Identifier : AIDSLINE MED/95267078; Mazumder A; Raghavan K; Weinstein J; Kohn KW; Pommier Y; Laboratory of Molecular Pharmacology, National Cancer Institute,; Bethesda, MD 20892-4255, USA.; Curcumin (diferuloylmethane) is the yellow pigment in turmeric (Curcuma longa L.) that is widely used as a spice, food coloring (curry) and preservative. Curcumin exhibits a variety of pharmacological effects including antitumor, anti-inflammatory, and anti-infectious activities and is currently in clinical trials for
Identification of human T cell leukemia/lymphoma virus type I antibodies, DNA, and protein in patients with polymyositis [see comments]: Arthritis Rheum. 1995 May;38(5):690-8. Unique Identifier : AIDSLINE MED/95267109; Sherman MP; Amin RM; Rodgers-Johnson PE; Morgan OS; Char G; Mora CA; Iannone R; Collins GH; Papsidero L; Gibbs CJ Jr; et al; State University of New York Health Science Center, Syracuse, NY; 13210, USA.; OBJECTIVE. To investigate a possible association between human T cell leukemia/lymphoma virus type I (HTLV-I) and polymyositis (PM). METHODS. Sera and muscle biopsy samples from 9 Jamaican PM patients were compared with specimens from American HTLV-I-positive PM patients and normal controls. Sera were evaluated for HT
Construction of gag, pol, and env specific riboprobes for confirmation of HIV-1 specific polymerase chain reaction products [corrected and republished article originally printed in J Virol Methods 1994 Jul;48(2-3):167-75]: J Virol Methods. 1995 Jan;51(1):131-9. Unique Identifier : AIDSLINE MED/95247865; Dolan J; Desselberger U; Regional Virus Laboratory, East Birmingham Hospital, UK.; Conserved regions of the gag, pol, and env genes of HIV-1 pBH10 DNA (gag nucleotides(nt)1508-1652, pol nt 2811-3118, env nt 7792-7934; Ratner et al., 1985) were amplified by the polymerase chain reaction (PCR) using oligonucleotides complementary to the termini of these regions as primers. Primer areas of the amplifie
Presence of HIV-1 proviral sequences in saliva of infected individuals in relation with clinical stage and CD4+ lymphocyte count.: Boll Soc Ital Biol Sper. 1994 Dec;70(12):345-52. Unique Identifier : AIDSLINE MED/95267399; Liuzzi G; Chirianni A; Tullio Cataldo P; Conte MC; Barsanti LA; Ceccherini Nelli L; Piazza M; Istituto di Malattie Infettive, Universita Federico II, Napoli.; We detected by PCR (Polymerase Chain Reaction) HIV-1 proviral sequences in saliva cells of 89 HIV+ subjects at different stages of disease. Twenty negative individuals not at risk of HIV infection were considered as controls. The amplification of DNA was performed using the primers of genomic env region SK68 and SK69.
Clinical features of immunodeficiency in man.: Hum Exp Toxicol. 1995 Jan;14(1):95-7. Unique Identifier : AIDSLINE MED/95267524; Breit SN; Centre for Immunology, St Vincent's Hospital, Sydney, Australia.
Do patients read health promotion posters in the waiting room? A study in one general practice.: Br J Gen Pract. 1994 Dec;44(389):583-5. Unique Identifier : AIDSLINE MED/95267571; Ward K; Hawthorne K; BACKGROUND. General practitioners are aware of the need to provide easily accessible health promotion information for their patients. Although many practices use health promotion posters in their surgeries, there appears to have been no formal evaluation of their effectiveness. AIM. A study was undertaken to investiga
Call for facts on HIV/AIDS exposure [news]: Nurs Stand. 1995 Apr 5-11;9(28):12. Unique Identifier : AIDSLINE MED/95267629
HIV infection after artificial insemination [news]: Nurs Stand. 1995 Apr 5-11;9(28):15. Unique Identifier : AIDSLINE MED/95267630; Areneta MR
AIDS focus. Advertising HIV.: Nurs Stand. 1995 Apr 5-11;9(28):50-2. Unique Identifier : AIDSLINE MED/95267639; Mougenez S; Howe J
AIDS focus. Same-day HIV testing.: Nurs Stand. 1995 Apr 5-11;9(28):53-6. Unique Identifier : AIDSLINE MED/95267640; Fernandez T
Anti-human immunodeficiency virus immunoconjugates.: Adv Pharmacol. 1995;32:205-47. Unique Identifier : AIDSLINE MED/95267703; Pincus SH; Tolstikov VV; Rocky Mountain Laboratories, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Hamilton,; Montana 59840, USA.
Type 2 phosphatidylinositol 4-kinase is recruited to CD4 in response to CD4 cross-linking.: Biochim Biophys Acta. 1995 Apr 27;1248(2):129-34. Unique Identifier : AIDSLINE MED/95267804; Pertile P; Cantley LC; Department of Medicine, Beth Israel Hospital, Boston, MA, USA.; CD4 serves as a cell-cell adhesion molecule, with specific affinity for class II MHC molecules, and as a receptor for the human immunodeficiency virus type 1 (HIV-1) viral coat protein. Phosphoinositide (PI)-3-kinase and 1-phosphatidylinositol (PtdIns)-4-kinase activities were previously found to associate with the CD
WHO Global AIDS Statistics.: AIDS Care. 1995;7(1):111-2. Unique Identifier : AIDSLINE MED/95267815
Injecting and sexual risk-taking behaviour among regular amphetamine users.: AIDS Care. 1995;7(1):19-26. Unique Identifier : AIDSLINE MED/95267816; Darke S; Ross J; Cohen J; Hando J; Hall W; National Drug and Alcohol Research Centre, University of New; South Wales, Kensington, Australia.; A sample of 301 regular amphetamine users were interviewed regarding injecting and sexual risk-taking behaviours. Two-thirds of subjects were injecting the drug, with males being 1.8 times more likely to do so. Nearly half (41%) of injectors had shared injecting equipment in the preceding month. Females were twice as
Paediatric AIDS: selected attitudes and behaviours of paediatricians in New York City hospitals.: AIDS Care. 1995;7(1):27-34. Unique Identifier : AIDSLINE MED/95267817; Bhushan V; Cushman LF; Metropolitan Hospital Center, New York Medical College, New York; 10029, USA.; This study provides survey data gathered from hospital-based paediatricians in New York City regarding several key issues in the diagnosis and treatment of paediatric AIDS. These include: perceived risk of acquiring HIV through professional exposure; referral patterns in the treatment of HIV-infected children; attitud
Orphan prevalence and extended family care in a peri-urban community in Zimbabwe.: AIDS Care. 1995;7(1):3-17. Unique Identifier : AIDSLINE MED/95267818; Foster G; Shakespeare R; Chinemana F; Jackson H; Gregson S; Marange C; Mashumba S; Paediatric Dept, Mutare Hospital, Zimbabwe.; An orphan enumeration survey was conducted in 570 households in and around Mutare, Zimbabwe in 1992; 18.3% (95% CI 15.1-21.5%) of households included orphans. 12.8% (95% CI 11.2-14.3%) of children under 15 years old had a father or mother who had died; 5% of orphans had lost both
Alcohol and drug use in heterosexual and homosexual prostitution, and its relation to protection behaviour.: AIDS Care. 1995;7(1):35-47. Unique Identifier : AIDSLINE MED/95267819; de Graaf R; Vanwesenbeeck I; van Zessen G; Straver CJ; Visser JH; The Netherlands Institute of Social Sexological Research (NISSO),; Utrecht.; To assess the prevalence and effects of alcohol and drug use in heterosexual and homosexual commercial contacts, and the relationship between their use and unsafe sexual behaviour, 127 female prostitutes, 27 male prostitutes, 91 clients of female prostitutes and 24 clients of male prostitutes were interviewed face-to-
Continuing medical education needs regarding AIDS among Egyptian physicians in Alexandria, Egypt and in the Asir Region, Saudi Arabia.: AIDS Care. 1995;7(1):49-54. Unique Identifier : AIDSLINE MED/95267820; Sallam SA; Mahfouz AA; Alakija W; al-Erian RA; Department of Epidemiology, Alexandria University, Egypt.; A study was carried out on two groups of Egyptian physicians to assess their continuing medical education (CME) needs regarding AIDS. The first group comprised 330 physicians working in Alexandria, Egypt, in Mother and Child Health Care Units, School Health Units and Health Offices. The second group included 144 physi
The measurement and significance of stressful life events in a cohort of homosexual HIV positive men.: AIDS Care. 1995;7(1):55-69. Unique Identifier : AIDSLINE MED/95267821; Nott KH; Vedhara K; Department of Psychology, University of Newcastle upon Tyne, UK.; Psychosocial HIV research has contributed greatly to our understanding of the psychosocial impact of the infection. However, assessments of stressful life events in homosexual HIV positive men have been made in the absence of a measurement tool specific to this patient group. This paper presents details of the constru
Risk of human immunodeficiency virus (HIV) transmission by anti-HIV-negative blood components in Germany and Austria.: Ann Hematol. 1995 Apr;70(4):209-13. Unique Identifier : AIDSLINE MED/95267881; Schwartz DW; Simson G; Baumgarten K; Fabritz H; Riggert J; Neumeyer H; Mayr WR; Kohler M; Department of Transfusion Medicine, University of Gottingen,; Germany.; In order to estimate the residual risk of transfusion-transmitted HIV infection we have analyzed the data from two transfusion centers in Austria (Vienna) and Germany (Gottingen) from 1985 to 1994. In Vienna, an incidence of 1:42,000 positive
[Antimicrobial prevention in primary care]: Aten Primaria. 1995 Apr 15;15(6):401-2, 404-6, 408-9. Unique Identifier : AIDSLINE MED/95267954; Miron JA; Lorenzo S; Escuela Nacional de Sanidad, Departamento de Promocion y; Prevencion, Madrid.
Epidemiology of viral infections in the Swedish blood-donor population.: Blood Coagul Fibrinolysis. 1994 Dec;5 Suppl 3:S13-7; discussion S19. Unique Identifier : AIDSLINE MED/95267967; Lindholm A; Blood Center, Ostra Hospital, Goteborg, Sweden.; The epidemiological situation regarding blood-borne infections in Sweden is favourable and under very good control. The prevalence of infectious markers in the blood-donor population is low. In 1993 the frequencies of confirmed positive tests were three in 1,000,000 for human immun
Viral safety of solvent/detergent-treated blood products.: Blood Coagul Fibrinolysis. 1994 Dec;5 Suppl 3:S21-8; discussion S29-S30. Unique Identifier : AIDSLINE MED/95267968; Horowitz B; Prince AM; Hamman J; Watklevicz C; New York Blood Center, NY 10021, USA.; Laboratory research that began in 1982 led to the licensing in the USA of a solvent/detergent (SD)-treated factor VIII concentrate in 1985. The licence was granted on the basis of several factors. First, studies had demonstrated the inactivation of several marker viruses (vesicular stomatitis virus, Sindbis virus, Sen
Clinical experience with the viral safety of immunoglobulins.: Blood Coagul Fibrinolysis. 1994 Dec;5 Suppl 3:S31-4; discussion S35. Unique Identifier : AIDSLINE MED/95267969; Hellstern P; Institute of Transfusion Medicine and Immunohaematology,; Ludwigshafen Hospital, Germany.; Preparations of intramuscular immunoglobulins (IMIGs) have not been reported to transmit viral disease since the inclusion of third-generation tests screening donor blood for hepatitis B virus. IMIGs and intravenous immunoglobulins (IVIGs) have never been a source of transmission of human immunodeficiency viruses. One
Virus validation of plasma-derived products produced by Pharmacia, with particular reference to immunoglobulins.: Blood Coagul Fibrinolysis. 1994 Dec;5 Suppl 3:S37-44. Unique Identifier : AIDSLINE MED/95267970; Eriksson B; Westman L; Jernberg M; Pharmacia AB, Stockholm, Sweden.; Important factors to assure the safety of plasma-derived products manufactured on an industrial scale are initial screening of the source material and validation of the manufacturing process in accordance with issued EEC guidelines and US [Points to Consider . Pharmacia s manufacturing process for immunoglobulins cont
Blood-borne viral infections.: Blood Coagul Fibrinolysis. 1994 Dec;5 Suppl 3:S5-10; discussion S11-2. Unique Identifier : AIDSLINE MED/95267971; Gurtler L; Max v. Pettenkofer-Institut fur Hygiene,; Ludwig-Maximilians-Universitat.; The selection of blood donors and the introduction of tests identifying virus-infected donors has led to a permanent increase in the safety of blood transfusion. In most European countries, there is a low risk of infection from viruses such as hepatitis B virus, hepatitis C virus and human immunodeficiency virus. Exam
[Pulmonary manifestations in HIV patients: role of thoracic radiography, CT and HRCT]: Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1995 Apr;162(4):282-7. Unique Identifier : AIDSLINE MED/95268010; Kauczor HU; Schnutgen M; Fischer B; Schwickert HC; Hartel S; Schadmand-Fischer S; Gerken G; Schweden F; Klinik fur Radiologie, Johannes-Gutenberg-Universitat Mainz.; AIM: To determine the prevalence of pulmonary changes on chest radiographs and computed tomography (CT/HRCT) in HIV patients and their relation to pulmonary symptoms. MATERIAL AND METHOD: 64 HIV patients were examined prospectively. 15 had no respiratory symptoms (group I), 30 had non-specific respiratory symptoms (gr
Diagnostic tests: statistical considerations.: Nutrition. 1995 Jan-Feb;11(1):56. Unique Identifier : AIDSLINE MED/95268240; Pagano M; Department of Biostatistics, Harvard School of Public Health,; Boston, Massachusetts, USA.
The discovery of drugs from higher plants.: Biotechnology. 1994;26:81-108. Unique Identifier : AIDSLINE MED/95268316; Kinghorn AD; Program for Collaborative Research in the Pharmaceutical; Sciences, College of Pharmacy, University of Illinois at Chicago,; USA.
Selection transduction defect (STD) due to Zap-70 kinase deficiency.: Immunodeficiency. 1995;5(3):193-211. Unique Identifier : AIDSLINE MED/95268475; Roifman CM; Division of Immunology/Allergy, Hospital for Sick Children,; Toronto, ON, Canada.; We have previously described a new type of selective T-cell deficiency (STD) characterized by persistent infections reminiscent of severe combined immunodeficiency (SCID). We show here that STD patients carry a mutation of zap-70 resulting in a loss of the activity of this kinase. The thymus of zap-70-/- patients show
The infection hazards of human cadavers [published erratum appears in Commun Dis Rep CDR Rev 1995 May 26;5(6):R92]: Commun Dis Rep CDR Rev. 1995 Apr 28;5(5):R61-8. Unique Identifier : AIDSLINE MED/95268491; Healing TD; Hoffman PN; Young SE; London Communicable Disease Surveillance Project, PHLS Central; Public Health Laboratory.; Cadavers may pose infection hazards to people who handle them. None of the organisms that caused mass death in the past--for example, plague, cholera, typhoid, tuberculosis, anthrax, smallpox--is likely to survive long in buried human remains. Items such as mould spores or lead dust are much greater risks to those inv
Infection in the deceased: a survey of management.: Commun Dis Rep CDR Rev. 1995 Apr 28;5(5):R69-73. Unique Identifier : AIDSLINE MED/95268492; Young SE; Healing TD; London Communicable Disease Surveillance Project.; Funeral directors, control of infection officers, chief environmental health officers, and consultants in communicable disease control were surveyed to identify the sources and nature of advice about infectious hazards from the deceased available to undertakers. They were asked about management responsibilities, polic
Finding common ground: the necessity of an integrated agenda for women's and children's health.: J Law Med Ethics. 1994 Fall;22(3):262-9; discussion 270-1. Unique Identifier : AIDSLINE MED/95268550; Chavkin W; Breitbart V; Wise PH
IL-10 secretion of allergen-specific skin-derived T cells correlates positively with that of the Th2 cytokines IL-4 and IL-5.: Exp Dermatol. 1994 Dec;3(6):304-13. Unique Identifier : AIDSLINE MED/95268649; Gutgesell C; Yssel H; Scheel D; Gerdes J; Neumann C; Department of Dermatology, University of Gottingen, Germany.; In atopic individuals, allergen-specific CD4+ T lymphocytes often belong to the T-helper 2 (Th2) subset as they secrete the marker cytokines interleukin-4 (IL-4) and IL-5 but not interferon-gamma (INF-gamma). IL-10 is a cytokine the production of which, in the mouse system has been described to be restricted to the Th
The morphogenesis of a Chinese strain of HIV-1 forming inclusion bodies in Jurkat-tat III cells.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):103-13. Unique Identifier : AIDSLINE MED/95268877; Li QG; Zhang YJ; Liang Y; Feng CQ; Li YZ; Sjoberg R; Jiang Y; Wang NF; Wadell G; Department of Virology, Institute of Infectious Diseases,; Beijing, China.; A rapid/high replicative strain of human immunodeficiency virus type 1 (HIV-1) (BC9101) was isolated directly in the Jurkat-tat III cell line from a Chinese patient with AIDS. The thin-section electron microscopy was performed and revealed high efficiency of replication of BC9101 with some unusual biological propertie
Early suppression of viremia by ZDV does not alter the spread of feline immunodeficiency virus infection in cats.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):114-22. Unique Identifier : AIDSLINE MED/95268878; Hayes KA; Wilkinson JG; Frick R; Francke S; Mathes LE; Department of Veterinary Pathobiology, Ohio State University,; Columbus 43210, USA.; Prophylactic zidovudine (ZDV) therapy in feline immunodeficiency virus (FIV) inoculated cats was evaluated for 12 months postinfection (pi) and 11 months post drug treatment. Plasma FIV antigenemia was prevented in six of six ZDV-treated and none of six untreated cats during the initial phase of infection. The present
Envelope V3 region sequences of Cuban HIV-1 isolates.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):123-5. Unique Identifier : AIDSLINE GENBANK/L37328; Rolo FM; Miranda L; Wainberg MA; Gu Z; Lobaina L; Noa E; Mato J; Machado F; Martin Z; National AIDS Research Laboratory, Havana, Cuba.; The origin of HIV-1 species, responsible for the AIDS epidemic in Cuba , is a subject that has been intensely debated. This study represents an initial attempt to shed light on this issue, through sequence analysis of the V3 regions of viruses isolated from 15 Cuban subjects. We now r
Life span of circulating membrane CD4 inserted into the plasma membranes of autologous red blood cells of HIV-infected subjects.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):126-32. Unique Identifier : AIDSLINE MED/95268880; Hollinger FB; Mouneimne Y; Lahart C; Tosi PF; Dimitrov D; Nicolau C; Division of Molecular Virology, Baylor College of Medicine,; Houston, Texas 77030-3498, USA.; Membrane recombinant CD4 was electroinserted into the plasma membrane of red blood cells (RBCs) from four HIV patients. CD4 had been labeled with 125I before electroinsertion. The RBCs-CD4-125I were labeled with 51Cr and autotransfused to the donor patients. The hematological indexes and the P50 value of the RBCs were
Comparison of multiple drug therapy regimens for HIV-related disseminated Mycobacterium avium complex disease.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):133-7. Unique Identifier : AIDSLINE MED/95268881; Kissinger P; Clark R; Morse A; Brandon W; Louisiana State University, Department of Medicine, New Orleans; 70112-2822, USA.; In June 1993, the United States Public Health Service (USPHS) made recommendations for treatment of disseminated Mycobacterium avium complex (MAC) in patients infected with the human immunodeficiency syndrome (HIV). It was suggested that every treatment regimen include either azithromy
Weekly oral etoposide in patients with Kaposi's sarcoma associated with human immunodeficiency virus infection: a phase I multicenter trial of the AIDS Clinical Trials Group.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):138-44. Unique Identifier : AIDSLINE MED/95268882; Paredes J; Kahn JO; Tong WP; Feldstein ML; Lin S; Bennett JM; Metroka CE; Ratner L; Krown SE; Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.; We conducted a Phase I trial to evaluate the safety, maximally tolerated dose (MTD), antitumor activity, and pharmacology of once-weekly oral etoposide in patients with Kaposi s sarcoma (KS) and AIDS. From September 1990 to October 1991, 27 eligible patients with biopsy-confirmed KS were treated at six etoposide dose
Phase I study of high-dose, intravenous rsCD4 in subjects with advanced HIV-1 infection.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):145-52. Unique Identifier : AIDSLINE MED/95268883; Schacker T; Collier AC; Coombs R; Unadkat JD; Fox I; Alam J; Wang JP; Eggert E; Corey L; University of Washington Department of Medicine, Seattle 98104,; USA.; In vitro, recombinant soluble CD4 (rsCD4) attaches to and inactivates human immunodeficiency virus (HIV). To determine if prolonged therapy with high-dose intravenous rsCD4 provides an in vivo benefit, we gave three HIV-1-infected patients with AIDS, whose isolates were susceptible in vitro to rsCD4, 10 mg/kg of rsCD4
Nucleoside analogue-associated peripheral neuropathy in human immunodeficiency virus infection.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):153-61. Unique Identifier : AIDSLINE MED/95268884; Simpson DM; Tagliati M; Department of Neurology, Mount Sinai Medical Center, New York, NY; 10029, USA.; Peripheral nerve disorders are among the most common neurological complications of HIV disease. Distal sensory polyneuropathy (DSP) is the most common form of neuropathy in patients with AIDS and can be caused by diverse mechanisms, including infectious, metabolic, inflammatory, nutritional, and toxic factors. Antiret
Analysis of nutritional intake in a cohort of homosexual men.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):162-7. Unique Identifier : AIDSLINE MED/95268885; Hogg RS; Zadra JN; Chan-Yan C; Voigt R; Craib KJ; Korosi-Ronco J; Montaner JS; Schechter MT; Vancouver Lymphadenopathy-AIDS Study, University of British; Columbia, Canada.; The objective of this study was to examine differences in the nutritional intake of seronegative (SN) and seropositive (SP) AIDS-free subjects within a cohort of gay men. The nutritional intake of 145 SN and 139 SP subjects between October 1991 and September 1992 was evaluated using a self-administered 24-h dietary re
Cryptococcal pneumonia in AIDS: is cryptococcal meningitis preceded by clinically recognizable pneumonia?: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):168-71. Unique Identifier : AIDSLINE MED/95268886; Driver JA; Saunders CA; Heinze-Lacey B; Sugar AM; Evans Memorial Department of Clinical Research, Boston University; Medical Center Hospital, MA 02118, USA.; Identification of cryptococcal infection while it is still in its pulmonary phase might improve the prognosis for patients with AIDS who contract cryptococcosis. Since cryptococcal pneumonia is infrequently diagnosed in the AIDS patient, especially compared with the frequency of diagnosis of cryptococcal meningitis, t
Accuracy of a saliva test for HIV antibody.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):172-5. Unique Identifier : AIDSLINE MED/95268887; King A; Marion SA; Cook D; Rekart M; Middleton PJ; O'Shaughnessy MV; Montaner JS; B.C. Centre for Disease Control, Faculty of Medicine, University; of British Columbia, Vancouver, Canada.; The accuracy of a saliva collection and testing protocol for determination of HIV-1 antibody status was assessed under realistic field conditions. The 1,256 study participants came from two lower-prevalence settings--a self-referral testing clinic (478) and a street-based outreach program (431)--and two high-prevalenc
Mycobacterium avium complex in water, food, and soil samples collected from the environment of HIV-infected individuals.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):176-82. Unique Identifier : AIDSLINE MED/95268888; Yajko DM; Chin DP; Gonzalez PC; Nassos PS; Hopewell PC; Reingold AL; Horsburgh CR Jr; Yakrus MA; Ostroff SM; Hadley WK; Department of Laboratory Medicine, University of California, San; Francisco General Hospital, USA.; As part of an epidemiologic study of Mycobacterium avium complex (MAC) infection in San Francisco, water, food and soil samples were collected from the home environment of 290 persons with human immunodeficiency virus (HIV) infection and cultured for mycobacteria. Isolates recovered from the environment were compared
Deferral of blood donors with risk factors for HIV infection saves lives and money in Zimbabwe.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):183-92. Unique Identifier : AIDSLINE MED/95268889; McFarland W; Kahn JG; Katzenstein DA; Mvere D; Shamu R; Center for AIDS Prevention Studies, University of California, San; Francisco 94105, USA.; We compared the cost-effectiveness of three strategies to avert transfusion-associated HIV infection in Zimbabwe : HIV antibody testing, deferral of donors with HIV risk factors, and deferral of donors with risk factors followed by antibody testing (Defer/Test). The Defer/Test str
U.S. hospital care for HIV-infected persons and the role of public and private teaching hospitals: 1988-1991.: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):193-203. Unique Identifier : AIDSLINE MED/95268890; Andrulis DP; McGregor CM; Weiss KB; Ramirez KL; Ginsberg CA; Shaw-Taylor Y; National Public Health and Hospital Institute, Washington, D.C.; 20005, USA.; Hospitals are a major provider of resources for individuals with HIV-related conditions. With the changing nature of HIV, tracking the dependence on and impact of related care delivered in these institutions is critical to monitoring overall resource need. This report documents HIV inpatient care in U.S. hospitals dur
HIV replication and lack of alteration of phytohemagglutinin-induced lymphokine production by peripheral blood mononuclear cells [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):204-6. Unique Identifier : AIDSLINE MED/95268891; Canque B; Rosenswajg M; Gluckman JC
Underutilization of the Papanicolaou smear in human immunodeficiency virus-positive women [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):206. Unique Identifier : AIDSLINE MED/95268892; Strigle SM; Walts AE
Decline in the incidence of cryptococcosis among HIV-infected patients [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):206-8. Unique Identifier : AIDSLINE MED/95268893; McNeil JI; Kan VL
Zidovudine use in pregnancy [letter; comment]: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):208-9. Unique Identifier : AIDSLINE MED/95268894; Eldridge RR
Zidovudine in pregnancy: is it dangerous for the fetus? [letter]: J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jun 1;9(2):209. Unique Identifier : AIDSLINE MED/95268895; Mandelbrot L; Guillonneau M; Jacqz-Aigrain E
Spinal arachnoiditis ossificans. Observations on its investigation and treatment.: Eur Spine J. 1995;4(1):60-3. Unique Identifier : AIDSLINE MED/95269049; Shiraishi T; Crock HV; Reynolds A; Cromwell Hospital, Spinal Disorders Unit, London, UK.; The histories of two patients with arachnoiditis ossificans leading to severe neurological impairment are presented. Analysis of these cases highlights the importance of three-dimensional (3 D) computed tomography (CT) scanning for the establishment of the diagnosis and in postoperative assessment of this rare disease
The HIV integrase catalytic core [news]: Nat Struct Biol. 1995 Feb;2(2):87-90. Unique Identifier : AIDSLINE MED/95269063; Plasterk RH
Serum IgE in patients with human immunodeficiency virus infection.: Ann Allergy Asthma Immunol. 1995 May;74(5):411-4. Unique Identifier : AIDSLINE MED/95269119; Mazza DS; Grieco MH; Reddy MM; Meriney D; Department of Medicine, St. Luke's/Roosevelt Hospital Center, R.; A. Cooke Institute of Allergy, Columbia University College of; Physicians & Surgeons, New York, New York, USA.; BACKGROUND: Dysregulation of IgE synthesis has been noted in the past in several immunodeficiency states. More recently, analysis of IgE synthesis and atopy in patients who are infected with the human immunodeficiency virus (HIV) has been conflicting. OBJECTIVE: To determine whether IgE dysregulation occurs in HIV-inf
Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene.: Immunity. 1995 May;2(5):473-83. Unique Identifier : AIDSLINE MED/95269131; Rooney JW; Hoey T; Glimcher LH; Department of Genetics Harvard Medical School, Boston,; Massachusetts 02115, USA.; The transcription factor NF-AT plays an essential role in the inducible transcription of several cytokine genes during T cell activation. The distal NF-AT site of the murine IL-2 promoter binds both NF-AT and AP-1 proteins, and thus represents a composite regulatory si
Profile of opportunistic infections among HIV-1 infected people in Hong Kong.: Chung Hua I Hsueh Tsa Chih (Taipei). 1995 Feb;55(2):127-36. Unique Identifier : AIDSLINE MED/95269208; Wong KH; Lee SS; Lo YC; Li PC; Ho HF; Sitt WH; Lam TW; Lai KY; Department of Health, Queen Elizabeth Hospital, Hong Kong.; BACKGROUND. To determine the spectrum of opportunistic infections in patients with human immunodeficiency virus (HIV-1) infection in Hong Kong . METHODS. A retrospective study of 214 HIV-1-infected patients, seen between December 198
New Canadian initiatives in dementia research [editorial]: Can J Neurol Sci. 1995 Feb;22(1):3-4. Unique Identifier : AIDSLINE MED/95269226; Pryse-Phillips W
Sensorimotor neuropathy and abnormal vitamin B12 metabolism in early HIV infection.: Can J Neurol Sci. 1995 Feb;22(1):43-6. Unique Identifier : AIDSLINE MED/95269229; Veilleux M; Paltiel O; Falutz J; Division of Neurology, Montreal General Hospital, Quebec.; Distal sensory peripheral neuropathy (DSPN) has been reported in 5 to 75% of patients with human immunodeficiency virus (HIV) infection, particularly in advanced stages of the disease. Twenty HIV seropositive patients were studied prospectively to determine the freque
Bilateral central ptosis in acquired immunodeficiency syndrome.: Can J Neurol Sci. 1995 Feb;22(1):52-5. Unique Identifier : AIDSLINE MED/95269233; Barton JJ; Kardon RH; Slagel D; Thompson HS; Department of Ophthalmology, University of Iowa Hospital and; Clinics, Iowa City, USA.; A man with acquired immune deficiency syndrome suddenly developed bilateral complete ptosis and minor vertical gaze limitation. Magnetic resonance imaging revealed a lesion in the midbrain surrounding the sylvian aqueduct in addition to bilateral masses in the caudate nuclei. Pathologic examination showed that the cau
111-indium-DTPA-IgG lung imaging in patients with pulmonary and HIV infection.: Chest. 1995 May;107(5):1336-41. Unique Identifier : AIDSLINE MED/95269500; Khalkhali I; Mena I; Rauh DA; Diggles LE; Pham HL; Mason GR; Division of Nuclear, Harbor-UCLA Medical Center, Torrance 90509,; USA.; 111-Indium-DTPA-IgG (111In-IgG) is a new radiopharmaceutical that has been evaluated for the detection of infection without the need for in vitro cell labeling. We prospectively studied this agent in 33 patients suspected of having lung infections, most of whom also had HIV infection, and three patients with HIV infec
[Computerized program -- new methods of hygienic education on the prevention of HIV infection in educational process]: Gig Sanit. 1994 Sep-Oct;(8):43-5. Unique Identifier : AIDSLINE MED/95270002; Liakhovich AV; Lozovskaia AS
Protective effect of LPS and poly A:U against immune oxidative injury: role of thiols released by activated macrophages.: Free Radic Biol Med. 1995 Apr;18(4):649-54. Unique Identifier : AIDSLINE MED/95270028; Fay M; Jampy-Fay M; Akarid K; Gougerot-Pocidalo MA; INSERM U 13, CHU X. Bichat, Paris, France.; Oxidative injury of immune cells has been observed both at inflammatory sites and in pathologic situations, such as human immunodeficiency virus infection. We used an ex vivo model of immune oxidative injury to test the antioxidant effect of two immunomodulating agents administered to C57B1/6 mice. Lipopolysaccharide
[Surgery in the era of acquired immunodeficiency syndrome]: Harefuah. 1995 Apr 2;128(7):430-4. Unique Identifier : AIDSLINE MED/95270076; Cohen-Kerem R; Assalia A; Hashmonai M
[Humin substances prevent entrance of HIV into the cell (news)]: Fortschr Med. 1995 Mar 10;113(7):15. Unique Identifier : AIDSLINE MED/95270127
Immunohistochemical localization of transforming growth factor-beta 1 in Kaposi's sarcoma.: Hum Pathol. 1995 May;26(5):469-73. Unique Identifier : AIDSLINE MED/95270194; Williams AO; Ward JM; Li JF; Jackson MA; Flanders KC; Laboratory of Experimental Pathology, National Cancer Institute,; National Institutes of Health, Bethesda, MD 20892, USA.; Immunohistochemical localization of transforming growth factor beta 1 (TGF-beta 1) was studied in Kaposi s sarcoma (KS) tissues obtained from autopsy and biopsy materials of patients with and without acquired immunodeficiency syndrome (AIDS) or human immunodeficiency virus (HIV) infection. There was no difference in t
Diarrheogenic bacterial enteritis in acquired immune deficiency syndrome: a light and electron microscopy study of 52 cases.: Hum Pathol. 1995 May;26(5):481-92. Unique Identifier : AIDSLINE MED/95270196; Orenstein JM; Kotler DP; Department of Pathology, George Washington University Medical; Center, Washington, DC 20037, USA.; Diarrhea, the etiology of which often is obscure, is a major complication of human immunodeficiency virus (HIV) disease. Diarrheogenic bacterial infections (eg, enteropathogenic Escherichia coli) are diagnosed traditionally by stool analysis rather than by examination of endoscopic biopsy specimens. Although E coli ra
Global eradication of donovanosis: an opportunity for limiting the spread of HIV-1 infection.: Genitourin Med. 1995 Feb;71(1):27-31. Unique Identifier : AIDSLINE MED/95270217; O'Farrell N; Department of Genitourinary Medicine, Guy's Hospital, London, UK.; Genital ulcer disease (GUD) is well recognised in the developing world as a co-factor for heterosexual HIV transmission. Men with GUD are an important high frequency HIV transmitter core group in the general population but few interventions have targeted such individuals so far. Donovanosis is an uncommon GUD with low
Progressive multifocal leukoencephalopathy in patients with AIDS: detection of JC virus DNA in CSF and brain [clinical conference]: Genitourin Med. 1995 Feb;71(1):35-40. Unique Identifier : AIDSLINE MED/95270219; Perrons CJ; Chinn RJ; Fox JD; Lucas SB; Harrison MJ; Miller RF; Department of Medical Microbiology, University College London; Medical School, UK.
Carcinoma of the penis in a HIV positive patient [see comments]: Genitourin Med. 1995 Feb;71(1):41-2. Unique Identifier : AIDSLINE MED/95270220; Yoganathan K; Patel RN; Maitland N; McManus TJ; Calman FM; Pozniak A; Department of Genitourinary Medicine, S E London Oncology Centre,; King's College Hospital, UK.
HTLV-I and HTLV-II in Africans [letter]: Genitourin Med. 1995 Feb;71(1):53. Unique Identifier : AIDSLINE MED/95270224; Vallejo A; Soriano V; Gutierrez M; Gomez C; Gonzalez-Lahoz J
Use of an inpatient HIV unit by injecting drug users [letter]: Genitourin Med. 1995 Feb;71(1):53-4. Unique Identifier : AIDSLINE MED/95270225; Grant AD; Finch EJ; Feinmann C; Miller RF
Assessment of contraceptive choice in HIV seropositive women [letter]: Genitourin Med. 1995 Feb;71(1):54-6. Unique Identifier : AIDSLINE MED/95270226; Carlin EM; Russell JM; Boag FC
The use of barrier contraceptives in Denmark during the AIDS epidemic [letter]: Genitourin Med. 1995 Feb;71(1):56-7. Unique Identifier : AIDSLINE MED/95270227; Petersen CS; Weismann K
Polypoidal and giant molluscum contagiosum in an AIDS patient [letter] [see comments]: Genitourin Med. 1995 Feb;71(1):57. Unique Identifier : AIDSLINE MED/95270228; Kumar B; Dawn G
HIV seropositivity in an STD centre in a cosmopolitan city in northern India [letter]: Genitourin Med. 1995 Feb;71(1):58-9. Unique Identifier : AIDSLINE MED/95270230; Ray K; Sachdeva KG; Jaisal NL; Tewari VK; Misra RS
T-helper type-1-dominated lymph node responses induced in C57BL/6 mice by optimally irradiated cercariae of Schistosoma mansoni are down-regulated after challenge infection.: Immunology. 1995 Feb;84(2):310-6. Unique Identifier : AIDSLINE MED/95270282; Pemberton RM; Wilson RA; Department of Biology, University of York, UK.; Following a single percutaneous vaccination with optimally irradiated cercariae of Schistosoma mansoni, C57BL/6 mice mount a T-helper type-1 (Th1) lymphocyte-dominant immune response and are highly resistant to challenge infection. In this study, we show that, besides interferon-gamma (IFN-gamma), lymph node (LN) cell
Rapid screening for Mamu-A1-positive rhesus macaques using a SIVmac Gag peptide-specific cytotoxic T-lymphocyte assay.: Immunology. 1995 Mar;84(3):482-7. Unique Identifier : AIDSLINE MED/95270308; Vogel T; Norley S; Beer B; Kurth R; Paul-Ehrlich Institute, Langen, Germany.; As part of an ongoing vaccine study using peptide immunogens designed to stimulate simian immunodeficiency virus (SIV)mac-specific cytotoxic T lymphocytes (CTL) it was necessary to identify rhesus macaques within our colony bearing the Mamu-A1 major histocompatibility complex (MHC) class I haplotype. Peripheral blood
Pathological lesions in HIV positive patients.: Indian J Med Res. 1995 Apr;101:134-41. Unique Identifier : AIDSLINE MED/95270317; Santosh V; Shankar SK; Das S; Pal L; Ravi V; Desai A; Sreedharan A; Khanna N; Chandramuki A; Satishchandra P; et al; Department of Neuropathology, National Institute of Mental Health; & Neuro Sciences, Bangalore.; Pathomorphological features of 10 HIV positive individuals studied at autopsy and biopsy are described. Nine patients had evidence of neuro-AIDS and eight of them succumbed to various opportunistic infections. One surviving patient underwent a diagnostic lymph node biopsy which revealed tuberculous lymphadenopathy.
A nonradioisotopic reverse phase dipstick hybridization method for detection of polymerase chain reaction amplified product.: Indian J Med Res. 1995 Apr;101:142-6. Unique Identifier : AIDSLINE MED/95270318; Bawa N; Broor S; Seth P; Department of Microbiology, All India Institute of Medical; Sciences, New Delhi.; A rapid and simple nonradioisotopic method has been developed for detection of polymerase chain reaction (PCR) amplified product. Digoxigenin-11-dUTP (DIG-11-dUTP) was incorporated in the amplified product by including it in the PCR reaction mixture. The PCR product was detected colorimetrically either directly or by
Lymphocyte subpopulations and concentrations of soluble CD8 and CD4 antigen after anaerobic training.: Int J Sports Med. 1995 Feb;16(2):117-21. Unique Identifier : AIDSLINE MED/95270351; Weiss C; Kinscherf R; Roth S; Friedmann B; Fischbach T; Reus J; Droge W; Bartsch P; Medical Clinic and Policlinic, Department of Sports and; Performance Medicine, Heidelberg, Germany.; In 13 middle-aged, moderately trained men (40-60 yr) we investigated the influence of anaerobic training on immunological parameters measured at rest. The 4 week anaerobic training program (two 30-min sessions weight lifting and one interval training per week; lactate levels 4-6 mM and 8-10 mM, respectively), caused a
Clinical classification of African Kaposi's sarcoma: time for reappraisal.: Int J Dermatol. 1995 Mar;34(3):166-7. Unique Identifier : AIDSLINE MED/95270365; Matondo P; University Teaching Hospital, Lusaka, Zambia.
Painful periungual telangiectasias in a patient with acquired immunodeficiency syndrome.: Int J Dermatol. 1995 Mar;34(3):199-200. Unique Identifier : AIDSLINE MED/95270375; Ruiz-Avila P; Tercedor J; Fuentes E; Villar A; Rodenas JM; Department of Dermatology, University Hospital, Granada, Spain.
Papulonecrotic tuberculid [letter; comment]: Int J Dermatol. 1995 Mar;34(3):217-9. Unique Identifier : AIDSLINE MED/95270382; Jordaan HF; Schneider JW
Grouping HLA-B locus serologic specificities according to shared structural motifs suggests that different peptide-anchoring pockets may have contrasting influences on the course of HIV-1 infection.: Hum Immunol. 1995 Jan;42(1):81-9. Unique Identifier : AIDSLINE MED/95270444; Itescu S; Rose S; Dwyer E; Winchester R; Department of Pediatrics, Columbia University, College of; Physicians and Surgeons, New York, NY 10032, USA.; Two different groups of HLA-B specificities were associated with two contrasting outcomes of HIV-1 infection. HLA-B45, -B49, and B50 were each found at a moderately increased frequency among individuals responding to HIV-1 infection with a marked circulating and infiltrative CD8 T-cell lymphocytosis, a slow rate of CD
Study of AZT effectiveness in treating HIV-infected children halted [news]: J Am Osteopath Assoc. 1995 Mar;95(3):211. Unique Identifier : AIDSLINE MED/95270454
Isolation of human immunodeficiency virus type 1 (HIV-1) RNA from feces by a simple method and difference between HIV-1 subpopulations in feces and serum.: J Clin Microbiol. 1995 Mar;33(3):581-8. Unique Identifier : AIDSLINE GENBANK/L38733; van der Hoek L; Boom R; Goudsmit J; Snijders F; Sol CJ; Human Retrovirus Laboratory, University of Amsterdam, The; Netherlands.; A simple method for the isolation and subsequent detection of human immunodeficiency virus type 1 (HIV-1) RNA from feces is described. Viral RNA was isolated by the method developed by Boom et al. (R. Boom, C.J.A. Sol, M.M.M. Salimans, C.L. Jansen, P.M.E. Wertheim-van Dillen, and J. van der Noordaa, J. Clin. Microbiol
Direct detection of proviral gag segment of human immunodeficiency virus in peripheral blood lymphocytes by colorimetric PCR assay as a clinical laboratory tool applied to different at-risk populations.: J Clin Microbiol. 1995 Mar;33(3):641-7. Unique Identifier : AIDSLINE MED/95270686; Pane F; Butto S; Gobbo ML; Franco M; Butteroni C; Pastore L; Maiorano G; Foggia M; Cataldo PT; Guarino A; et al; CEINGE-Biotecnologie Avanzate, Universita di Napoli Federico II,; Italy.; We used a colorimetric polymerase chain reaction (PCR)-based assay in kit form to detect directly human immunodeficiency virus type 1 (HIV-1) proviral gag sequences in peripheral blood cells from 68 healthy blood donors, 51 subjects at risk for HIV infection, 122 patients with HIV-1 infection, 11 patients with indeter
Use of a multiplex PCR to detect and identify Mycobacterium avium and M. intracellulare in blood culture fluids of AIDS patients [see comments]: J Clin Microbiol. 1995 Mar;33(3):668-74. Unique Identifier : AIDSLINE MED/95270691; Kulski JK; Khinsoe C; Pryce T; Christiansen K; Department of Microbiology, Royal Perth Hospital, Australia.; The presence of mycobacteria in blood culture fluids (BACTEC) of AIDS patients with positive growth indices (GIs, > 20 U) was investigated by using a multiplex PCR to detect and identify members of the genus Mycobacterium, M. avium, M. intracellulare, and M. tuberculosis. Three different methods of extracting mycobact
Characterization of genetically distinct subgroup of Candida albicans strains isolated from oral cavities of patients infected with human immunodeficiency virus.: J Clin Microbiol. 1995 Mar;33(3):696-700. Unique Identifier : AIDSLINE MED/95270696; McCullough M; Ross B; Reade P; School of Dental Science, Faculty of Medicine, Dentistry, and; Health Science, University of Melbourne, Victoria, Australia.; During the course of a study of oral Candida albicans strains from 60 human immunodeficiency virus-infected patients over a 2.5-year period, 18 of the 295 C. albicans isolates had genomes that failed to hybridize with a C. albicans-specific DNA probe (27A). These strains were germ tube positive and chlamydospore posit
Culture of intestinal biopsy specimens and stool culture for detection of bacterial enteropathogens in patients infected with human immunodeficiency virus. The Berlin Diarrhea/Wasting Syndrome Study Group.: J Clin Microbiol. 1995 Mar;33(3):745-7. Unique Identifier : AIDSLINE MED/95270707; Liesenfeld O; Schneider T; Schmidt W; Sandforth J; Weinke T; Zeitz M; Riecken EO; Ullrich R; Institute of Medical Microbiology and Infectious Diseases; Immunology, Free University of Berlin, Germany.; The diagnostic yields of stool cultures and biopsy specimens for the detection of enteric bacterial pathogens in 213 human immunodeficiency virus-infected patients were compared. Forty-five percent (19 of 42) of the pathogens were detected exclusively by stool culture, 2% (1 of 42) of the isolates were detected exclus
Molecular epidemiology of Candida isolates from AIDS patients showing different fluconazole resistance profiles.: J Clin Microbiol. 1995 Mar;33(3):769-71. Unique Identifier : AIDSLINE MED/95270714; Lischewski A; Ruhnke M; Tennagen I; Schonian G; Morschhauser J; Hacker J; Zentrum fur Infektionsforschung, Universitat Wurzburg,; Germany.; Thirty Candida isolates obtained from the oropharynxes of three AIDS patients were genotypically characterized. In vitro fluconazole MIC determination revealed increasing fluconazole resistances during treatment, thereby confirming the in vivo situation. Pulsed-field gel electrophoresis karyotyping, randomly amplified
Optimum recovery of Mycobacterium avium complex from blood specimens of human immunodeficiency virus-positive patients by using small volumes of isolator concentrate inoculated into BACTEC 12B bottles [letter; comment]: J Clin Microbiol. 1995 Mar;33(3):784-5. Unique Identifier : AIDSLINE MED/95270719; Wasilauskas BL; Morrell R Jr
Plasma endothelin and Kaposi's sarcoma.: J Am Acad Dermatol. 1995 Jun;32(6):1048-9. Unique Identifier : AIDSLINE MED/95270775; Cacoub P; Coutellier A; Maistre G; de Gennes C; Frances C; Piette JC; Godeau P; Department of Internal Medicine, CHU La Pitie-Salpetriere,; France.
Idiopathic CD4+ T lymphocytopenia in a patient with mycosis fungoides [letter; comment]: J Am Acad Dermatol. 1995 Jun;32(6):1063-4. Unique Identifier : AIDSLINE MED/95270785; Stevens SR; Griffiths TW; Cooper KD
Zidovudine for the treatment of HIV-negative patients with psoriasis: a pilot study [see comments]: J Am Acad Dermatol. 1995 Jun;32(6):994-9. Unique Identifier : AIDSLINE MED/95270796; Townsend BL; Cohen PR; Duvic M; Department of Dermatology, University of Texas-Houston Medical; School 77030, USA.; BACKGROUND: Zidovudine, an inhibitor of HIV replication, has been reported to improve psoriasis in HIV-positive patients. OBJECTIVE: Our purpose was to evaluate the safety, tolerance, and effectiveness of oral zidovudine for treating psoriasis in HIV-negative patients in a small, open-label study. METHODS: Each subjec
Cognitive-behavioral intervention to reduce African American adolescents' risk for HIV infection.: J Consult Clin Psychol. 1995 Apr;63(2):221-37. Unique Identifier : AIDSLINE MED/95270808; St. Lawrence JS; Brasfield TL; Jefferson KW; Alleyne E; O'Bannon RE 3rd; Shirley A; Community Health Program, Jackson State University, Mississippi; 39217-0105, USA.; Two hundred forty-six African American adolescents were randomly assigned to an educational program or an 8-week intervention that combined education with behavior skills training including correct condom use, sexual assertion, refusal, information provision, self-management, problem solving, and risk recognition. Ski
HIV risk in intravenous drug users and crack cocaine smokers: predicting stage of change for condom use.: J Consult Clin Psychol. 1995 Apr;63(2):238-48. Unique Identifier : AIDSLINE MED/95270809; Bowen AM; Trotter R 2nd; Department of Psychology, Northern Arizona University, Flagstaff; 86011-5105, USA.; This study examined the utility of the Transtheoretical Model of Change and the AIDS Risk Reduction Model for predicting condom use with not-in-treatment crack cocaine smokers and intravenous drug users. The sample included 265 participants; 99 reported having casual partners and 166 reported having main partners. All
Optimal scaling of HIV-related sexual risk behaviors in ethnically diverse homosexually active men.: J Consult Clin Psychol. 1995 Apr;63(2):270-9. Unique Identifier : AIDSLINE MED/95270813; Cochran SD; de Leeuw J; Mays VM; Department of Psychology, California State University, Northridge; 91330, USA.; As HIV-related behavioral research moves increasingly in the direction of seeking to determine predictors of high-risk sexual behavior, more efficient methods of specifying patterns are needed. Two statistical techniques, homogeneity analysis and latent class analysis, useful in scaling binary multivariate data profil
Immunologic aspects of hyperimmunoglobulinemia E-like syndrome in patients with AIDS.: J Allergy Clin Immunol. 1995 May;95(5 Pt 1):995-1003. Unique Identifier : AIDSLINE MED/95270848; Paganelli R; Scala E; Mezzaroma I; Pinter E; D'Offizi G; Fanales-Belasio E; Rosso RM; Ansotegui IJ; Pandolfi F; Aiuti F; Department of Allergy and Clinical Immunology, University La; Sapienza, Rome, Italy.; In this study we describe a series of nine patients affected by acquired immunodeficiency syndrome (AIDS) or AIDS-related complex who had hypereosinophilia and hyperimmunoglobulinemia E (hyper-IgE) with chronic dermatitis and recurrent staphylococcal infections. These patients had features similar to those present in
Role of different methods for the detection of diarrhoeal pathogens in HIV-infected patients in Brazil.: J Diarrhoeal Dis Res. 1994 Dec;12(4):287-9. Unique Identifier : AIDSLINE MED/95270906; Belo MT; Trajman A; Perez AC; Zaltman C; Barroso PF; Elia CC; Department of Internal Medicine, University Hospital, Federal; University of Rio de Janeiro, Brazil.; To evaluate the ability of different diagnostic methods for the detection of AIDS-related diarrhoeal pathogens in developing countries, we studied 40 HIV-infected patients with diarrhoea. All patients were subjected to stool examinations for parasites, stool culture and peroral jejunal biopsy. Jejunal specimens were p
T helper 2 cells are subject to high dose oral tolerance and are not essential for its induction.: J Immunol. 1995 Jun 1;154(11):5649-55. Unique Identifier : AIDSLINE MED/95270957; Garside P; Steel M; Worthey EA; Satoskar A; Alexander J; Bluethmann H; Liew FY; Mowat AM; Department of Immunology, Western Infirmary, University of; Glasgow, Scotland.; Oral administration of aqueous protein Ag results in profound immunologic tolerance, and it has been suggested previously that this reflects selective activation of Th subsets. Here we show that the induction of oral tolerance by feeding a single high dose of OVA to mice significantly reduces the production of both Th
Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo.: J Immunol. 1995 Jun 1;154(11):5684-93. Unique Identifier : AIDSLINE MED/95270961; Huleatt JW; Lefrancois L; Division of Rheumatic Diseases, University of Connecticut Health; Center, Farmington 06030, USA.; Intraepithelial lymphocytes (IEL) of the intestinal epithelium represent a phenotypically and functionally distinct subpopulation of peripheral T cells. In this study, we report the production of a mAb, designated HL3, which exhibits reactivity with a subset of IEL. In differential screening assays HL3 reacted with 30
T cell development in insulin-like growth factor-II transgenic mice.: J Immunol. 1995 Jun 1;154(11):5736-45. Unique Identifier : AIDSLINE MED/95270966; Kooijman R; van Buul-Offers SC; Scholtens LE; Schuurman HJ; Van den Brande LJ; Zegers BJ; Department of Immunology, University Hospital for Children and; Youths, Utrecht, The Netherlands.; Growth hormone and insulin-like growth factor-I (IGF-I) have been demonstrated to play a role in T and B cell development. We studied the effects of IGF-II on T cell development in two transgenic mouse lines that overexpress human IGF-II under the control of the H2Kb promoter. The thymuses of 1-wk-old mice of two tran
A protease-dependent TCR-induced death pathway in mature lymphocytes.: J Immunol. 1995 Jun 1;154(11):5806-12. Unique Identifier : AIDSLINE MED/95270973; Sarin A; Nakajima H; Henkart PA; Experimental Immunology Branch, National Cancer Institute,; National Institutes of Health, Bethesda, MD 20892, USA.; Several cysteine and serine protease inhibitors previously shown to block TCR-induced death of 2B4 T hybridoma cells were tested for their ability to block various T lymphocyte apoptotic death systems. TCR-induced death of both peripheral CD4+ and CD8+ T cell blasts
Infection of IL-4-deficient mice with the parasitic nematode Brugia malayi demonstrates that host resistance is not dependent on a T helper 2-dominated immune response.: J Immunol. 1995 Jun 1;154(11):5995-6001. Unique Identifier : AIDSLINE MED/95270994; Lawrence RA; Allen JE; Gregory WF; Kopf M; Maizels RM; Wellcome Research Centre for Parasitic Infections, Department of; Biology, Imperial College of Science, Technology and Medicine,; London, United Kingdom.; Resistance of intact mice to infection with the filarial nematode, Brugia malayi is dependent on the presence of T cells. To investigate the role of Th2 cells in this protection, mice with a targeted disruption of the IL-4 gene were infected with different developmental stages of B. malayi. We examined the phenotypic
HIV-1 infection of human macrophages impairs phagocytosis and killing of Toxoplasma gondii.: J Immunol. 1995 Jun 1;154(11):6132-9. Unique Identifier : AIDSLINE MED/95271009; Biggs BA; Hewish M; Kent S; Hayes K; Crowe SM; Walter and Eliza Hall Institute of Medical Research, Melbourne,; Victoria, Australia.; The susceptibility of patients with AIDS to certain opportunistic infections is due to defective cell-mediated immunity. The contribution of direct infection of macrophages with HIV-1 to this defect is unknown. To address this issue, we infected normal human monocyte-derived macrophages with a monocytotropic strain of
High prevalence of serum IgA HIV-1 infection-enhancing antibodies in HIV-infected persons. Masking by IgG.: J Immunol. 1995 Jun 1;154(11):6163-73. Unique Identifier : AIDSLINE MED/95271012; Kozlowski PA; Black KP; Shen L; Jackson S; Department of Microbiology, University of Alabama at Birmingham; 35294, USA.; IgA and IgG purified from sera of 20 HIV-infected persons were separately examined for ability to mediate Ab-dependent enhancement (ADE) of HIV-1 infection of U937 cells. Both isotypes were capable of enhancing infection of these cells. However, IgA from twice as many persons (14/20) displayed infection enhancement wh
Mortality and survival trends in patients with AIDS in north east England from 1984-1992.: J Infect. 1995 Jan;30(1):23-7. Unique Identifier : AIDSLINE MED/95271019; Dorrell L; Snow MH; Ong EL; Infectious Diseases Unit, Newcastle General Hospital, Newcastle; Upon Tyne, U.K.; OBJECTIVE: to study trends in mortality and survival in patients with AIDS attending an ID unit. METHOD: retrospective analysis of patients developing an AIDS-defining illness between April 1984, and November 1992. Survival was analysed by calculation of survival product-limit. RESULTS: 71 patients were analysed (incl
Prolonged cryptosporidiosis during primary HIV infection.: J Infect. 1995 Jan;30(1):51-3. Unique Identifier : AIDSLINE MED/95271025; Moss PJ; Read RC; Kudesia G; McKendrick MW; Department of Infectious Diseases and Medicine, Royal Hallamshire; Hospital, Sheffield, U.K.; Primary infection with the human immunodeficiency virus causes profound immunosuppression with a decrease in lymphocyte numbers and function. However, this immunosuppression is transient and most individuals regain normal immune function. Infection with opportunist pathogens during the period of immunosuppression is r
Mycobacterium avium: a potentially treatable cause of pericardial effusions.: J Infect. 1995 Jan;30(1):55-8. Unique Identifier : AIDSLINE MED/95271026; Choo PS; McCormack JG; University Department of Medicine, University of Queensland,; South Brisbane, Australia.; We present a patient with a very large pericardial effusion due to disseminated Mycobacterium avium complex (MAC) infection with associated bacteraemia and gastroenteritis. He was HIV antibody-positive with a CD4+ lymphocyte count of 10 x 10(6)/l. He complained of fevers, diarrhoea and dyspnoea and an echocardiogram s
Mycobacterium avium complex (MAC) osteomyelitis and septic arthritis in an immunocompetent host.: J Infect. 1995 Jan;30(1):59-62. Unique Identifier : AIDSLINE MED/95271027; Jones AR; Bartlett J; McCormack JG; University of Queensland Department of Medicine and Infectious; Diseases, Mater Misericordiae Hospital, South Brisbane,; Australia.; We describe a case of Mycobacterium avium complex (MAC) osteomyelitis and septic arthritis in an immunocompetent man. Infection was derived from a chainsaw injury sustained on the lateral aspect of the ankle 13 years earlier, and had spread through the bone, joint and soft tissue emerging at the medial aspect. This wa
Risks and behaviour in patients requesting HIV tests.: J Infect. 1995 Jan;30(1):71-3. Unique Identifier : AIDSLINE MED/95271031; Wardropper AG; Sankar KN; Ong EL; Department of Genitourinary Medicine, Newcastle General Hospital,; U.K.; A prospective survey to assess reasons for requesting HIV tests, perceived HIV risk and sexual behaviour in genitourinary medicine clinic attenders was carried out. Overall 123 (38.6%) were concerned about casual sexual contacts. Homosexual and bisexual men may have changed their sexual behaviour as a result of public
HIV-1 seroconversion in pregnancy without materno-fetal transmission of the virus [letter]: J Infect. 1995 Jan;30(1):81-2. Unique Identifier : AIDSLINE MED/95271033; Portolani M; De Rienzo B; Pecorari M; Pietrosemoli P; Meacci M; Sabbatini AM
Spontaneous Salmonella peritonitis in HIV infection [letter]: J Infect. 1995 Jan;30(1):87-8. Unique Identifier : AIDSLINE MED/95271038; Laing RB; Wynn RF; Leen CL; Stansfield R
Epstein-Barr virus coinfection and recombination in non-human immunodeficiency virus-associated oral hairy leukoplakia [see comments]: J Infect Dis. 1995 May;171(5):1122-30. Unique Identifier : AIDSLINE MED/95271045; Walling DM; Clark NM; Markovitz DM; Frank TS; Braun DK; Eisenberg E; Krutchkoff DJ; Felix DH; Raab-Traub N; Department of Microbiology and Immunology, University of North; Carolina, Chapel Hill 27599-7295, USA.; Human immunodeficiency virus-associated oral hairy leukoplakia (HLP) is characterized by coinfection with multiple types and strains of Epstein-Barr virus (EBV) and recombination within the EBV genome. HIV-seronegative immunosuppressed and immunocompetent patients with HLP were examined to determine the pathogenic con
Human immunodeficiency virus type 1 (HIV-1) viremia changes and development of drug-related mutations in patients with symptomatic HIV-1 infection receiving alternating or simultaneous zidovudine and didanosine therapy [see comments]: J Infect Dis. 1995 May;171(5):1152-8. Unique Identifier : AIDSLINE MED/95271049; Kojima E; Shirasaka T; Anderson BD; Chokekijchai S; Steinberg SM; Broder S; Yarchoan R; Mitsuya H; Experimental Retrovirology Section, National Cancer Institute,; Bethesda, MD 20892, USA.; The changes in viremia levels and the development of drug-related mutations were examined in 26 patients with symptomatic human immunodeficiency virus type 1 (HIV-1) infection participating in a randomized trial comparing alternating (A) and simultaneous (S) regimens of zidovudine and didanosine therapy. Patients on b
Evaluation of safety and efficacy of 3TC (lamivudine) in patients with asymptomatic or mildly symptomatic human immunodeficiency virus infection: a phase I/II study.: J Infect Dis. 1995 May;171(5):1166-71. Unique Identifier : AIDSLINE MED/95271051; van Leeuwen R; Katlama C; Kitchen V; Boucher CA; Tubiana R; McBride M; Ingrand D; Weber J; Hill A; McDade H; et al; Department of Internal Medicine (Clinical AIDS Unit), University; of Amsterdam, Academic Medical Centre, Netherlands.; In a phase I/II study, 7 levels of 3TC therapy (from 0.5 to 20.0 mg/kg/day) were studied in 104 asymptomatic and mildly symptomatic human immunodeficiency virus-infected patients with CD4 cell counts
Five-year follow-up of a phase I study of didanosine in patients with advanced human immunodeficiency virus infection.: J Infect Dis. 1995 May;171(5):1180-9. Unique Identifier : AIDSLINE MED/95271053; Nguyen BY; Yarchoan R; Wyvill KM; Venzon DJ; Pluda JM; Mitsuya H; Broder S; Medicine Branch, National Cancer Institute, National Institutes; of Health, Bethesda, MD 20892, USA.; Starting in 1988, 72 patients with advanced human immunodeficiency virus (HIV) infection were enrolled in a phase I study of didanosine at the National Cancer Institute. Beginning in 1992, patients with decreases in CD4 cell counts could switch to a combination of zidovudine and didanosine. The estimated median surviv
Influence of neurologic manifestations of primary human immunodeficiency virus infection on disease progression. SEROCO Study Group.: J Infect Dis. 1995 May;171(5):1190-5. Unique Identifier : AIDSLINE MED/95271054; Boufassa F; Bachmeyer C; Carre N; Deveau C; Persoz A; Jadand C; Sereni D; Bucquet D; SEROCO and HEMOCO Adult Cohorts, INSERM U 292, Les Cabanons; Hopital de Bicetre, Le Kremlin-Bicetre, France.; To determine the influence of neurologic manifestations of primary human immunodeficiency virus (HIV) infection on disease progression, 277 nonhemophiliac adults enrolled
Vitamin A deficiency and wasting as predictors of mortality in human immunodeficiency virus-infected injection drug users [see comments]: J Infect Dis. 1995 May;171(5):1196-202. Unique Identifier : AIDSLINE MED/95271055; Semba RD; Caiaffa WT; Graham NM; Cohn S; Vlahov D; Department of Ophthalmology, Johns Hopkins School of Medicine,; Baltimore, Maryland, USA.; A nested case-control study of vitamin A deficiency and wasting as risk factors for mortality from AIDS and infections was done within a large prospective cohort of human immunodeficiency virus (HIV)-infected injection drug users (IDUs). Fifty adult subjects who died from AIDS and infections were matched with 235 cont
Pre- and postexposure protection against human immunodeficiency virus type 1 infection mediated by a monoclonal antibody.: J Infect Dis. 1995 May;171(5):1203-9. Unique Identifier : AIDSLINE MED/95271056; Gauduin MC; Safrit JT; Weir R; Fung MS; Koup RA; Aaron Diamond AIDS Research Center, New York, NY 10016, USA.; Monoclonal antibody BAT123 was passively transferred into SCID mice reconstituted with human peripheral blood lymphocytes (hu-PBL-SCID) to study passive antibody protection against human immunodeficiency virus type 1 (HIV-1) infection. BAT123 is specific for the third variable loop of the gp120 of HIV-1LAI. Animals we
Response of recent human immunodeficiency virus seroconverters to the pneumococcal polysaccharide vaccine and Haemophilus influenzae type b conjugate vaccine.: J Infect Dis. 1995 May;171(5):1217-22. Unique Identifier : AIDSLINE MED/95271058; Weiss PJ; Wallace MR; Oldfield EC 3rd; O'Brien J; Janoff EN; Department of Internal Medicine (Infectious Disease Division),; Naval Medical Center, San Diego, California, USA.; Antibody responses in recent human immunodeficiency virus (HIV) seroconverters to 2 vaccines were studied. Twenty patients infected with HIV for
T helper cell type 1 (Th1)- and Th2-like responses are present in mice with gastric candidiasis but protective immunity is associated with Th1 development.: J Infect Dis. 1995 May;171(5):1279-88. Unique Identifier : AIDSLINE MED/95271067; Cenci E; Mencacci A; Spaccapelo R; Tonnetti L; Mosci P; Enssle KH; Puccetti P; Romani L; Bistoni F; Department of Experimental Medicine and Biochemical Sciences,; University of Perugia, Italy.; The relative contributions of local T helper cell type 1 (Th1)- and Th2-like responses to the course of primary and secondary gastrointestinal (GI) candidiasis were examined in adult immunocompetent BALB/c mice. Both Th1 cytokines, such as interferon-gamma (IFN-gamma), and the Th2 cytokines, interleukin (IL)-4 and IL-
Adverse events associated with trimethoprim-sulfamethoxazole and atovaquone during the treatment of AIDS-related Pneumocystis carinii pneumonia.: J Infect Dis. 1995 May;171(5):1295-301. Unique Identifier : AIDSLINE MED/95271069; Hughes WT; LaFon SW; Scott JD; Masur H; Department of Infectious Diseases, St. Jude Children's Research; Hospital, Memphis, TN 38101, USA.; Atovaquone was compared to trimethoprim-sulfamethoxazole (TMP-SMZ) for the relationship of time receiving therapy, plasma drug concentrations, and incidence of adverse reactions in patients with AIDS-associated Pneumocystis carinii pneumonia. Treatment-limiting adverse events occurred in 9% of atovaquone-treated patie
Class II major histocompatibility complex-deficient mice initially control an infection with Leishmania major but succumb to the disease.: J Infect Dis. 1995 May;171(5):1302-8. Unique Identifier : AIDSLINE MED/95271070; Chakkalath HR; Theodos CM; Markowitz JS; Grusby MJ; Glimcher LH; Titus RG; Department of Tropical Public Health, Harvard School of Public; Health, Boston, Massachusetts, USA.; Class II major histocompatibility complex (MHC)-deficient (H-2b) mice do not express I-A or I-E molecules and, as a result, do not develop CD4 cells. Thus, they represent the ideal model for examining the importance of CD4 cells and MHC class II molecules in resistance to infection with Leishmania major and the capaci
Antimicrobial response of a T cell-deficient host to cytokine therapy: effect of interferon-gamma in experimental visceral leishmaniasis in nude mice.: J Infect Dis. 1995 May;171(5):1309-16. Unique Identifier : AIDSLINE MED/95271071; Murray HW; Hariprashad J; Aguero B; Arakawa T; Yeganegi H; Division of Infectious Diseases, Cornell University Medical; College, New York, New York, USA.; To determine if interferon (IFN)-gamma can enhance intracellular antimicrobial defense in a T cell-deficient host, nude BALB/c mice were infected with Leishmania donovani and treated with IFN-gamma. IFN-gamma induced killing of L. donovani in livers of euthymic mice but had no effect in nude mice despite activating pe
New virologic tools for the design and analysis of clinical trials [editorial; comment]: J Infect Dis. 1995 May;171(5):1325-8. Unique Identifier : AIDSLINE MED/95271074; Shafer RW; Merigan TC; While a large number of candidate drugs and drug combinations are being evaluated for treating human immunodeficiency virus (HIV) infection, clinicians are confronted by the problem of how to optimally use those antiretroviral drugs already approved for clinical use. While new techniques are being developed for studyi
Clinical, immunologic, and virologic observations related to human immunodeficiency virus (HIV) type 1 infection in a volunteer in an HIV-1 vaccine clinical trial [see comments]: J Infect Dis. 1995 May;171(5):1343-7. Unique Identifier : AIDSLINE MED/95271078; Kahn JO; Steimer KS; Baenziger J; Duliege AM; Feinberg M; Elbeik T; Chesney M; Murcar N; Chernoff D; Sinangil F; AIDS Program, San Francisco General Hospital, CA 94110, USA.; A vaccine breakthrough occurred in a phase 1 clinical trial of a human immunodeficiency virus (HIV) type 1 candidate subunit vaccine. The vaccine antigen, gp120SF2, is a fully glycosylated protein produced in mammalian cells from the HIVSF2 isolate. After 4 immunizations, the subject developed neutralizing antibodies
Polymerase chain reaction and culture confirmation of disseminated Encephalitozoon cuniculi in a patient with AIDS: successful therapy with albendazole.: J Infect Dis. 1995 May;171(5):1375-8. Unique Identifier : AIDSLINE MED/95271086; De Groote MA; Visvesvara G; Wilson ML; Pieniazek NJ; Slemenda SB; daSilva AJ; Leitch GJ; Bryan RT; Reves R; Division of Infectious Diseases, University of Colorado Health; Sciences Center, Denver 80262, USA.; Infections due to microsporidia are being recognized increasingly, especially in AIDS patients. A patient with disseminated microsporidiosis with advanced renal failure due to Encephalitozoon cuniculi (confirmed by culture and polymerase chain reaction [PCR]) is descri
[Clinico-pathological aspect of HIV-sero positive inpatients]: Kansenshogaku Zasshi. 1995 Apr;69(4):398-403. Unique Identifier : AIDSLINE MED/95271113; Fujita H; Soga T; Suzuki J; Ishigatsubo Y; Mohri H; Okubo T; Nagashima Y; Misugi K; First Department of Internal Medicine, Yokohama City University; School of Medicine.; To describe the clinico-pathological aspect of HIV/AIDS inpatients, we reviewed HIV/AIDS inpatients in our hospital since 1988. We evaluated risk factors, CD4 counts, CD4/8 ratio, cause of death and the survival time after diagnosis of AIDS. A total of 13 HIV sero-positive subjects were admitted to our hospital, inclu
[Study on transgenic mice growing into craniofacial anomaly]: Kokubyo Gakkai Zasshi. 1995 Mar;62(1):56-77. Unique Identifier : AIDSLINE MED/95271167; Kikuchi S; Department of Pedodontics, Faculty of Dentistry, Tokyo Medical; and Dental University.; In order to elucidate the genetic effects on the growth and development of craniofacial regions, HIV-1 transgenic mice (TG mice) which exhibited the phenotype of anterior crossbites were investigated by various methods. Northern hybridization showed that the introduced gene was expressed from 14.5 days post coitum to
PRO-LIGAND: an approach to de novo molecular design. 1. Application to the design of organic molecules.: J Comput Aided Mol Des. 1995 Feb;9(1):13-32. Unique Identifier : AIDSLINE MED/95271242; Clark DE; Frenkel D; Levy SA; Li J; Murray CW; Robson B; Waszkowycz B; Westhead DR; Proteus Molecular Design Ltd., Macclesfield, Cheshire, U.K.; An approach to de novo molecular design, PRO-LIGAND, has been developed that, in the environment of a large, integrated molecular design and simulation system, provides a unified framework for the generation of novel molecules which are either similar or complementary to a specified target. The approach is based on a
Use of polymerase chain reaction for improved diagnosis of tuberculosis in children.: J Pediatr. 1995 May;126(5 Pt 1):703-9. Unique Identifier : AIDSLINE MED/95271398; Delacourt C; Poveda JD; Chureau C; Beydon N; Mahut B; de Blic J; Scheinmann P; Garrigue G; Service de Pneumo-Pediatrie, Hopital des Enfants Malades,; Paris, France.; OBJECTIVE: To study the value of a rapid diagnostic method based on the amplification by polymerase chain reaction (PCR) of a fragment of the IS6110 insertion element for the detection of Mycobacterium tuberculosis in children. DESIGN: We tested 199 specimens obtained from 68 children referred for evaluation of suspec
Encephalopathy in children with perinatally acquired human immunodeficiency virus infection. Pediatric Spectrum of Disease Clinical Consortium.: J Pediatr. 1995 May;126(5 Pt 1):710-5. Unique Identifier : AIDSLINE MED/95271399; Lobato MN; Caldwell MB; Ng P; Oxtoby MJ; Pediatric and Family Studies Section, Division of HIV/AIDS,; National Center for Infectious Diseases, Centers for Disease; Control and Prevention, Atlanta, Georgia 30333, USA.; OBJECTIVE: To define the incidence, characteristics, and survival of children with perinatally acquired human immunodeficiency virus (HIV) infection and encephalopathy. DESIGN: Cross-sectional and longitudinal data collected from 1811 HIV-infected children in a multicenter active surveillance study. SETTING: Health de
Effect of corticosteroids on survival of children with acquired immunodeficiency syndrome and Pneumocystis carinii-related respiratory failure [see comments]: J Pediatr. 1995 May;126(5 Pt 1):821-4. Unique Identifier : AIDSLINE MED/95271423; McLaughlin GE; Virdee SS; Schleien CL; Holzman BH; Scott GB; Department of Pediatrics, University of Miami School of Medicine,; Florida 33101, USA.; The medical records of patients with acquired immunodeficiency syndrome were reviewed to evaluate the effect of our adoption to the pediatric population of the National Institutes of Health recommendation for adjunctive corticosteroid therapy in adults with Pneumocystis carinii pneumonia. In 21 episodes of P. carinii-
[Immunohistochemical study of the endomyocardial biopsy of systemic lupus erythematosus]: J Cardiol. 1995 Apr;25(4):181-8. Unique Identifier : AIDSLINE MED/95271462; Sakaguchi Y; Nakamura Y; Sutani T; Tsuchihashi M; Yamano S; Hashimoto T; Dohi K; Hiasa Y; Kawai S; Okada R; First Department of Internal Medicine, Nara Medical University.; The mechanisms of cardiac involvement in systemic lupus erythematosus (SLE) were studied using immunohistochemical staining of endomyocardial biopsy specimens from 14 patients with SLE and normal coronary arteriograms. All 14 specimens showed mild interstitial edema, 11 showed mild cardiac fibrosis, and another two ca
Molecular similarity from atomic electrostatic multipole comparisons. Application to anti-HIV drugs.: J Med Chem. 1995 May 12;38(10):1635-40. Unique Identifier : AIDSLINE MED/95271610; Burgess EM; Ruell JA; Zalkow LH; Haugwitz RD; School of Chemistry and Biochemistry, Georgia Institute of; Technology, Atlanta 30332, USA.; A procedure is presented for the rapid calculation of the similarity between a pair of molecules based on atomic electrostatic multipole comparison. The multipoles are derived from semiempirical SCF wave functions, and the results obtained compare favorably with ab initio results. The method is illustrated by correlat
The human immunodeficiency virus long terminal repeat includes a specialised initiator element which is required for Tat-responsive transcription.: J Mol Biol. 1995 May 5;248(3):562-80. Unique Identifier : AIDSLINE MED/95271649; Rittner K; Churcher MJ; Gait MJ; Karn J; MRC Laboratory of Molecular Biology, Cambridge, UK.; The effects of mutations in human immunodeficiency virus type-1 (HIV-1) long terminal repeat on initiation and on Tat-mediated trans-activation were studied using cell-free transcription assays. All the elements that are necessary for efficient transcription initiation in vitro are included in the core promoter. This
Users of free treatment slots at a community-based methadone maintenance clinic.: J Subst Abuse Treat. 1995 Jan-Feb;12(1):13-8. Unique Identifier : AIDSLINE MED/95271724; Wells EA; Fleming C; Calsyn DA; Jackson TR; Saxon AJ; Department of Psychiatry and Behavioral Sciences, University of; Washington, Seattle, USA.; At a community-based methadone clinic in Seattle, WA, 360 opiate-addicted individuals were enrolled in a treatment demonstration project. The treatment slots were free to clients and, unlike other funded treatment slots, did not require proof of eligibility based on documentation of indigence. The clients were compare
HIV serosurveillance of newborns. A clinician's perspective on legislative, political, and ethical issues.: J Subst Abuse Treat. 1995 Jan-Feb;12(1):29-33. Unique Identifier : AIDSLINE MED/95271726; Garrett C; Department of Psychiatry, North Shore University Hospital-Cornell; University Medical Center, Manhasset, NY 11030, USA.; This article reviews the complex issues surrounding the anonymous HIV testing of newborns to monitor the prevalence of HIV infection in women of childbearing age. This serosurveillance of newborns has become a topic of legislative debate focusing on disclosure of currently anonymous results of HIV antibody tests of ne
Infectious diseases.: JAMA. 1995 Jun 7;273(21):1686-8. Unique Identifier : AIDSLINE MED/95271856; Stoeckle M; Douglas RG Jr; Cornell University Medical College, New York, NY, USA.; Cryptosporidiosis is increasingly recognized to be a major cause of diarrheal disease in the United States . Improved strategies for prophylaxis of opportunistic infections in persons with advanced HIV disease have been identified. Zidovudine was shown to decrease perinatal transmission
Obstetrics and gynecology.: JAMA. 1995 Jun 7;273(21):1700-2. Unique Identifier : AIDSLINE MED/95271864; Quilligan EJ; University of California-Irvine College of Medicine, Orange, USA.; Treating HIV-infected pregnant patients and the newborn with zidovudine reduced the percentage of HIV-infected infants. Uterine myomas are being treated effectively with gonadotropin-releasing hormone analogues. Nonoperative therapy is being used in the patient with an ectopic pregnancy.
[Antiretroviral treatment: are we entering or exiting the tunnel?]: Med Clin (Barc). 1995 Apr 29;104(16):622-5. Unique Identifier : AIDSLINE MED/95272202; Gatell JM; Miro JM; Servicio de Infecciones, Hospital Clinica i Provincial,; Barcelona.
Impact of HIV on delivery of health care in sub-Saharan Africa: a tale of secrecy and inertia [editorial] [see comments]: Lancet. 1995 May 27;345(8961):1315-7. Unique Identifier : AIDSLINE MED/95272236
An attenuated vaccine for AIDS? [comment]: Lancet. 1995 May 27;345(8961):1318-9. Unique Identifier : AIDSLINE MED/95272238; Beale J
Herpesvirus-like DNA sequences in non-Kaposi's sarcoma skin lesions of transplant patients.: Lancet. 1995 May 27;345(8961):1339-40. Unique Identifier : AIDSLINE MED/95272244; Rady PL; Yen A; Rollefson JL; Orengo I; Bruce S; Hughes TK; Tyring SK; Department of Microbiology and Immunology, University of Texas; Medical Branch, Galveston 77555-1019, USA.; Herpesvirus-like DNA sequences (KSHV) have been reported to be associated with various forms of Kaposi s sarcoma (KS). To determine if KSHV was associated with other proliferative skin lesions from non-AIDS immunocompromised patients, 33 skin lesions (basal cell carcinomas, squamous cell carcinomas, actinic keratoses,
Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells [see comments]: Lancet. 1995 May 27;345(8961):1342-4. Unique Identifier : AIDSLINE MED/95272246; Almond N; Kent K; Cranage M; Rud E; Clarke B; Stott EJ; National Institute for Biological Standards and Control, Potters; Bar, Herts, UK.; A vaccine against AIDS will probably have to protect against challenge both by viable virus-infected cells and by cell-free virus. Eight cynomolgus macaques infected with attenuated simian immunodeficiency virus (SIV) were challenged (four each) with cell-free and cell-associated SIV. All were protected, whereas eight
Cancer and HIV infection in Rwanda [letter]: Lancet. 1995 May 27;345(8961):1378-9. Unique Identifier : AIDSLINE MED/95272287; Newton R; Grulich A; Beral V; Sindikubwabo B; Ngilimana PJ; Nganyira A; Parkin DM
Run training versus cross-training: effect of increased training on circulating leukocyte subsets.: Med Sci Sports Exerc. 1995 Mar;27(3):355-62. Unique Identifier : AIDSLINE MED/95272355; Pizza FX; Flynn MG; Sawyer T; Brolinson PG; Starling RD; Andres FF; Department of Health Promotion and Human Performance, University; of Toledo, OH 43606, USA.; The purpose of this study was to determine the effects of increased training via cross-training (run + cycle) and run training on circulating leukocyte subsets. Male runners (N = 11) participated in two randomly assigned increased training (IT) periods after 30 d of normal training (NT). Each IT began after a 14 d per
Exercise-induced muscle damage: effect on circulating leukocyte and lymphocyte subsets.: Med Sci Sports Exerc. 1995 Mar;27(3):363-70. Unique Identifier : AIDSLINE MED/95272356; Pizza FX; Mitchell JB; Davis BH; Starling RD; Holtz RW; Bigelow N; Department of Physical Education, Texas Christian University,; Fort Worth 76129, USA.; The purpose of this study was to determine the effect of downhill and level running on circulating leukocyte and lymphocyte subsets and T lymphocyte activation. Using a random cross-over design, 10 runners completed two trials of 60 min of level running (0% grade; LR) and downhill running (-10% grade; DHR) at 70% of l
Fluorescence resonance energy transfer.: Methods Enzymol. 1995;246:300-34. Unique Identifier : AIDSLINE MED/95272427; Selvin PR; Calvin Laboratory, Lawrence Berkeley Laboratory, University of; California, Berkeley 94720, USA.
Optically detected magnetic resonance of photoexcited triplet states.: Methods Enzymol. 1995;246:610-38. Unique Identifier : AIDSLINE MED/95272440; Maki AH; Department of Chemistry, University of California, Davis 95616,; USA.
Penicillium marneffei infection in an AIDS patient--a first case report from Malaysia.: Med J Malaysia. 1995 Mar;50(1):101-4. Unique Identifier : AIDSLINE MED/95272460; Rokiah I; Ng KP; Soo-Hoo TS; Department of Medicine, Faculty of Medicine, University of; Malaya, Kuala, Lumpur.; We report a 39-year-old male who presented with tuberculous meningitis and was found also to be HIV-infected. In the course of his illness, he developed multiple opportunistic infections such as herpes genitalis, oesophageal candidiasis, CMV retinitis and finall
Update: trends in AIDS among men who have sex with men--United States, 1989-1994.: MMWR Morb Mortal Wkly Rep. 1995 Jun 2;44(21):401-4. Unique Identifier : AIDSLINE MED/95272512; During 1994, local, state, and territorial health departments reported to CDC 34,974 cases of acquired immunodeficiency syndrome (AIDS) among men whose only reported HIV exposure was sexual contact with other men. Although previous reports indicated progressively smaller annual increases in cases of AIDS among men who
HIV transmission in a dialysis center--Colombia, 1991-1993.: MMWR Morb Mortal Wkly Rep. 1995 Jun 2;44(21):404-5, 411-2. Unique Identifier : AIDSLINE MED/95272513; Although never reported in the United States , previous reports of possible patient-to-patient transmission of human immunodeficiency virus (HIV) associated with hemodialysis (1,2) indicate the potential for this problem and the importance of infection-control measures in dialysis cente
cDNA cloning and eukaryotic expression of feline CD9.: Mol Immunol. 1995 Apr;32(6):417-23. Unique Identifier : AIDSLINE GENBANK/X76489; Willett BJ; Neil JC; Department of Veterinary Pathology, University of Glasgow; Veterinary School, U.K.; A monoclonal antibody (vpg15) has been described which can block infection with feline immunodeficiency virus (FIV) and which recognizes the feline homologue of CD9. In order to study the role of feline CD9 in infection with FIV we have molecularly cloned a cDNA encoding feline CD9 by R.A.C.E (rapid amplification of c
Long-term survivors of human immunodeficiency virus type 1 infection [letter; comment]: N Engl J Med. 1995 Jun 15;332(24):1647; discussion 1647-8. Unique Identifier : AIDSLINE MED/95272652; Dunkle LM
Long-term survivors of human immunodeficiency virus type 1 infection [letter]: N Engl J Med. 1995 Jun 15;332(24):1647; discussion 1647-8. Unique Identifier : AIDSLINE MED/95272653; Farid NR
Long-term survivors of human immunodeficiency virus type 1 infection [letter; comment]: N Engl J Med. 1995 Jun 15;332(24):1647; discussion 1647-8. Unique Identifier : AIDSLINE MED/95272654; Whyte J
Regeneration of T cells after chemotherapy [letter; comment]: N Engl J Med. 1995 Jun 15;332(24):1651-2. Unique Identifier : AIDSLINE MED/95272662; Moreland LW; Bucy RP; Koopman WJ
[HIV infection and AIDS in women and children (see comments)]: Ned Tijdschr Geneeskd. 1995 May 13;139(19):964-6. Unique Identifier : AIDSLINE MED/95272740; Bol P; Gezondheidsraad, Den Haag.
[Gynecological aspects of HIV infection and AIDS]: Ned Tijdschr Geneeskd. 1995 May 13;139(19):966-70. Unique Identifier : AIDSLINE MED/95272741; van Oppen AC; Boer K; Bol P; Academisch Ziekenhuis, afd. Obstetrie, Utrecht.
[HIV and pregnancy]: Ned Tijdschr Geneeskd. 1995 May 13;139(19):970-5. Unique Identifier : AIDSLINE MED/95272742; Boer K; Mulder-Kampinga GA; Scherpbier HJ; Afd. Verloskunde en Gynaecologie, Academisch Medisch Centrum,; Amsterdam.
[HIV infection and AIDS in children]: Ned Tijdschr Geneeskd. 1995 May 13;139(19):975-9. Unique Identifier : AIDSLINE MED/95272743; Scherpbier HJ; Mulder-Kampinga GA; Bol P; Boer K; Afd. Neonatologie en Kindergeneeskunde, Academisch Medisch; Centrum, Amsterdam.
[Children with HIV/AIDS; initial experiences with school placement]: Ned Tijdschr Geneeskd. 1995 May 13;139(19):979-82. Unique Identifier : AIDSLINE MED/95272744; Mulder-Folkerts DK; Bindels PJ; Coutinho RA; Gemeentelijke en Geneeskundige Gezondheidsdienst, sector; Volksgezondheid en Milieu, Amsterdam.
[AIDS, also a gynecological diagnosis]: Ned Tijdschr Geneeskd. 1995 May 13;139(19):982-5. Unique Identifier : AIDSLINE MED/95272745; Huikeshoven FJ; Olofsen-van Acht MJ; van der Ende ME; Afd. Verloskunde en Gynaecologie, Academisch Ziekenhuis; Rotterdam-Dijkzigt.; In two women (aged 30 and 39), both addicted to heroin and HIV seropositive, cervical intraepithelial neoplasia and infiltrating squamous cell carcinoma of the cervix respectively were diagnosed. Treatment consisted of exconisation and radiotherapy respectively. Adding invasive cervical carcinoma to the AIDS-defining
[Drug reactions occur frequently in patients with HIV infection]: Ned Tijdschr Geneeskd. 1995 May 13;139(19):985-8. Unique Identifier : AIDSLINE MED/95272746; Koopmans PP; van der Ven AL; Vree TB; van der Meer JW; Afd. Algemeen Inwendige Geneeskunde, Academisch Ziekenhuis,; Nijmegen.; Three HIV-infected patients, men of 28 and 43 years old, and a woman of 32 years old, developed cutaneous reactions to one or more drugs prescribed to treat secondary infections. An increased incidence of hypersensitivity reactions to sulfonamides has been reported in literature. HIV-seropositive patients, however, ap
[HIV and reproductive choices]: Ned Tijdschr Geneeskd. 1995 May 13;139(19):989-94. Unique Identifier : AIDSLINE MED/95272747; Boer K; de Vries JW; de Beaufort IE; Academisch Medisch Centrum, afd. Verloskunde, Gynaecologie en; Neonatologie, Amsterdam.
[Prevalence of HIV antibodies in pregnant women in the Amsterdam HIV reference station research, 1988-1993]: Ned Tijdschr Geneeskd. 1995 May 13;139(19):994-7. Unique Identifier : AIDSLINE MED/95272748; Bindels PJ; Mulder-Folkerts DK; Schutte MF; Wong FJ; Smit I; Boer K; Gemeenitelijke en Geneeskundige Gezondheidsdienst, sector; Volksgezondheid en Milieu, Amsterdam.; Pregnant women were asked to undergo a HIV test in two hospitals, one maternity clinic (n = 12.784; 1988-1993) and one abortion clinic (n = 2089; 1990-1993) in Amsterdam, in order to establish trends in HIV prevalence. Participation rates were 92.4% and 84.4%, respectively. Among pregnant women the overall HIV prevale
[Evaluation of tests recommended by the CDC for the determination of CD4+ T lymphocytes in patients infected by the human immunodeficiency virus]: Pathol Biol (Paris). 1994 Nov;42(9):830-5. Unique Identifier : AIDSLINE MED/95273133; Elbim C; Gastal C; Gougerot-Pocidalo MA; Service d'Immunologie et d'Hematologie, CHU X. Bichat, Paris,; France.; The Centers for Disease Control (CDC) recently published the guidelines for the performance of CD4+ T-cell determinations in persons with Human Immunodeficiency Virus (HIV) infection. Especially, a monoclonal antibody panel for lymphocyte immunophenotyping has been recommended i.e CD45/CD14, isotypic controls, CD3/CD4
[Free dissociated and precipitated p24 antigenemia of HIV-1 in subjects of the black race]: Pathol Biol (Paris). 1994 Nov;42(9):855-60. Unique Identifier : AIDSLINE MED/95273137; Dragon MA; Matta M; Prazuck T; Payan C; Belec L; Laboratoire de Virologie, Hopital Broussais, Paris, France.; P24/HIV-1 antigen in the sera from 41 HIV-1-infected Black individuals, living in the Central African Republic (n = 17) and in France (n = 24), and in 21 HIV-1-infected Caucasians patients, matched on the stages of the disease, h
[Syndrome of hemophagocytosis associated with infections]: Pathol Biol (Paris). 1994 Nov;42(9):861-7. Unique Identifier : AIDSLINE MED/95273138; Sotto A; Bessis D; Porneuf M; Taib J; Ciurana AJ; Jourdan J; Service de Medecine Interne B, Hopital Caremeau, CHU Nimes,; France.; Infection-related hemophagocytic syndrome was originally described in viral processes by Risdall in 1979. Recent reports have suggested associations of this syndrome with bacterial, parasitic and fungal infections. It occurs generally in immunosuppressed patients. The clinical and biological manifestations are not spe
Transmission of human parvovirus B19 by plasma derived factor VIII concentrates.: Nouv Rev Fr Hematol. 1994 Dec;36(6):449-53. Unique Identifier : AIDSLINE MED/95273158; Laurian Y; Dussaix E; Parquet A; Chalvon-Demersay A; d'Oiron R; Tchernia G; Centre de Traitement pour Hemophiles, Hopital Bicetre, Le; Kremlin-Bicetre, France.; Although clotting factor concentrates prepared from large pools of plasma are considered to be safe for enveloped viruses (HIV, HBV and HCV), these products are likely to remain at risk for non lipid enveloped viruses. The prevalence of positive IgG serology for human parvovirus B19 (HPV-B19) was determined in 53 chil
TB and HIV testing could be combined [news]: Nurs Times. 1995 Apr 26-May 2;91(17):10. Unique Identifier : AIDSLINE MED/95273200; Espinol MA; Reingold AI; Koenig E
What is sexuality?: Nurs Times. 1995 Apr 26-May 2;91(17):26-7. Unique Identifier : AIDSLINE MED/95273205; Van Oijen E; Charnock A
Burnout associated with caring for people living with HIV/AIDS.: Nurs Times. 1995 May 3-9;91(18):34-5. Unique Identifier : AIDSLINE MED/95273224; Lempp H; Burnout has been one of the major concerns among health professionals when caring for people living with HIV/AIDS. Having been clinically involved with this client group in hospital and community settings for over 10 years the author considers what has helped her to avoid becoming physically and emotionally exhausted.
Current perspectives on AIDS/HIV education and counseling [editorial]: Patient Educ Couns. 1994 Dec;24(3):191-8. Unique Identifier : AIDSLINE MED/95273262; Visser A; Antoni M; This whole issue of Patient Education and Counseling is devoted to current perspectives on AIDS/HIV education and counseling. The results of 15 completed empirical studies and empirically-based reviews are described, highlighting the central role of education and counseling in research and clinical practice in the AID
Measurement of condom use in 72 studies of HIV-preventive behaviour: a critical review.: Patient Educ Couns. 1994 Dec;24(3):199-216. Unique Identifier : AIDSLINE MED/95273263; Sheeran P; Abraham C; Ninety-four distinct measures of condom use were identified in a review of 72 psychosocial studies of HIV-prevention. A coding scheme was developed which characterised each measure in terms of: (1) type of measure (e.g. frequency of use, use at last intercourse), (2) response alternatives (e.g. Likert scale), (3) reca
Psychosocial counseling to improve quality of life in HIV infection.: Patient Educ Couns. 1994 Dec;24(3):217-35. Unique Identifier : AIDSLINE MED/95273264; Lutgendorf S; Antoni MH; Schneiderman N; Fletcher MA; Psychosocial interventions such as cognitive behavioral stress management (CBSM), may enhance coping and social support which contribute to an improvement of quality of life factors such as emotional functioning, social functioning, and sense of well-being, for HIV-infected men during several phases of HIV spectrum di
Psychosocial correlates and the effects of behavioral interventions on the course of human immunodeficiency virus infection in homosexual men.: Patient Educ Couns. 1994 Dec;24(3):237-47. Unique Identifier : AIDSLINE MED/95273265; Mulder CL; The course of infection with the human immunodeficiency virus (HIV) varies widely among individuals. It is hypothesized that some of the variation is due to psychosocial factors, including stressful life events, psychological distress, ways of coping with HIV infection, and the quality of the social network. This arti
Readability of HIV/AIDS educational materials: the role of the medium of communication, target audience, and producer characteristics.: Patient Educ Couns. 1994 Dec;24(3):249-59. Unique Identifier : AIDSLINE MED/95273266; Wells JA; The reading difficulty of many HIV/AIDS brochures and pamphlets limits their effectiveness. This analysis addresses correlates of readability in 136 HIV/AIDS educational items. Readability is measured using the SMOG Index. The medium of communication is significantly related to readability: comic books and brochures a
Effects of two formats of informed consent on knowledge amongst persons with advanced HIV disease in a clinical trial of didanosine.: Patient Educ Couns. 1994 Dec;24(3):261-6. Unique Identifier : AIDSLINE MED/95273267; Tindall B; Forde S; Ross MW; Goldstein D; Barker S; Cooper DA; To determine subjects perception of the purpose of informed consent, 113 subjects were recruited from a dose-controlled clinical trial of didanosine (ddI). Subjects were surveyed regarding how they made decisions regarding their medical care in general, about how they obtained information about this trial in particul
HIV-1 antibody testing among drug users participating in AIDS education.: Patient Educ Couns. 1994 Dec;24(3):267-78. Unique Identifier : AIDSLINE MED/95273268; McCusker J; Bigelow C; Zapka JG; Zorn M; Stoddard AM; Lewis BF; This study aimed to identify factors which predict participation of drug users in HIV-1 antibody testing. The study was part of a randomized controlled trial of three small group AIDS educational programs, in a 21-day in-patient drug detoxification and rehabilitation program. Subjects (n = 497) were clients admitted t
Increase in safe sex among the young and non-monogamous: knowledge, attitudes and behavior regarding safe sex and condom use in The Netherlands from 1987 to 1993.: Patient Educ Couns. 1994 Dec;24(3):279-88. Unique Identifier : AIDSLINE MED/95273269; de Vroome EM; Paalman ME; Dingelstad AA; Kolker L; Sandfort TG; In 1987, the Dutch STD Foundation started several safe sex campaigns targeting the general population. These campaigns have been accompanied by surveys which were conducted every 6 months. Questions were asked about knowledge, attitudes and behavior. The number of people who regard condom use as being a safe sex pract
Social transmission routes of HIV. A combined sexual network and life course perspective.: Patient Educ Couns. 1994 Dec;24(3):289-97. Unique Identifier : AIDSLINE MED/95273270; Reinking D; van Zessen G; Kretzschmar M; Brouwers H; Jager JC; Stringer P; A combined sexual network and lifecourse perspective is proposed as a basis for reconstructing the sexological infrastructure of HIV dissemination. Necessary data are drawn from a representative sample survey of 1001 adults (age range 18-50 years) in the Netherlands . Heterosex
Focus group interviews with risk-taking gay men: appraisal of AIDS prevention activities, explanations for sexual risk-taking, and needs for support.: Patient Educ Couns. 1994 Dec;24(3):299-306. Unique Identifier : AIDSLINE MED/95273271; Hospers HJ; Molenaar S; Kok G; Recently, several findings demonstrated an increase in high-risk sexual behaviour among gay men. This study conducted focus groups with gay men who engaged in risk-taking behaviour with casual partners. Three issues were addressed: appraisal of current AIDS prevention activities, explanations for sexual risk-taking, a
Contextual and interactional factors influencing condom use in heterosexual prostitution contacts.: Patient Educ Couns. 1994 Dec;24(3):307-22. Unique Identifier : AIDSLINE MED/95273272; Vanwesenbeeck I; van Zessen G; de Graaf R; Straver CJ; The protection behavior of prostitutes and prostitutes clients has been studied from a contextual and an interactional point of view. Different protection styles (subject s cognitive and behavioral position regarding condom use) have been identified in both prostitutes (N = 119) and clients (N = 91). Risk-taking pros
Public reactions towards people with AIDS: an attributional analysis.: Patient Educ Couns. 1994 Dec;24(3):323-35. Unique Identifier : AIDSLINE MED/95273273; Peters L; den Boer DJ; Kok G; Schaalma HP; This article addresses the issue of stigmatization and discrimination towards people with AIDS (PWAs) using Weiner s attributional theory of motivation and emotion. In a field experiment, subjects responded to vignettes describing patients with AIDS, syphilis, lung cancer or tuberculosis. In these vignettes, the onset
Teachers' attitudes towards AIDS: an explorative study is Israel.: Patient Educ Couns. 1994 Dec;24(3):337-40. Unique Identifier : AIDSLINE MED/95273274; Brook U; A study was held among 54 high school teachers working in one of five high schools in Holon ( Israel ). They filled out a questionnaire on attitudes about HIV/AIDS in general and on euthanasia in patients terminally ill with AIDS. Thirty-nine percent of the teachers answered that a p
Development and evaluation of an inventory for rating client satisfaction with outcome in HIV counseling: the Albion Center scale.: Patient Educ Couns. 1994 Dec;24(3):341-5. Unique Identifier : AIDSLINE MED/95273275; Begley K; Ross MW; Austin P; Casey K; Collins P; Hennings G; Agriesti L; Marshall K; We developed an inventory for rating client satisfaction with outcome in HIV counseling, based on interview responses with clients. The resulting 19-item scale was subject to factor analysis and four factors, accounting for 56% of the variance, emerged. The factors described dimensions of Perception of progress and im
From a traditional public health approach to self-organization: three steps in a decade of HIV/AIDS.: Patient Educ Couns. 1994 Dec;24(3):347-51. Unique Identifier : AIDSLINE MED/95273276; Blans J
An adjustment to HIV scale.: Patient Educ Couns. 1994 Dec;24(3):353-4. Unique Identifier : AIDSLINE MED/95273277; Ross MW
[Fever evolution after treatment in patients with tuberculosis and HIV infection]: Rev Clin Esp. 1995 Mar;195(3):150-3. Unique Identifier : AIDSLINE MED/95273721; Moreno S; Baraia J; Parras F; Solera J; Bernacer B; Meana A; Bouza E; Servicio de Microbiologia Clinica, Hospital General Gregorio; Maranon, Madrid.; OBJECTIVES. To compare the fever course after starting therapy in patients diagnosed of active tuberculosis with and without HIV infection and evaluate the usefulness of empiric antituberculous therapy in diagnosing the disease. METHODS. Review of clinical records from all patients meeting the following criteria for t
[The adult respiratory stress syndrome and septic shock associated with tuberculosis]: Rev Clin Esp. 1995 Mar;195(3):160-3. Unique Identifier : AIDSLINE MED/95273723; Boronat M; Arzuaga JA; Diez Balda V; Chamorro C; Salas C; Lopez de Letona JM; Servicio de Medicina Interna II, Clinica Puerta de Hierro,; Universidad Autonoma de Madrid.; The increase in the incidence of tuberculosis infection in the last few years has caused a recurrence of atypical clinical forms, as well as the development of associations and uncommon complications during the clinical course, which include the adult respiratory distress syndrome (ARDS) and septic shock. Three patien
[A painful swelling on the thigh of a patient with the acquired immunodeficiency syndrome]: Rev Clin Esp. 1995 Mar;195(3):191-2. Unique Identifier : AIDSLINE MED/95273727; Ramos JM; Robledo AG; Turrion F; Fernandez-Guerrero ML; Unidad de Enfermedades Infecciosas, Fundacion Jimenez Diaz,; Universidad Autonoma de Madrid.
[Hyperpotassemia during the treatment of Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole (letter)]: Rev Clin Esp. 1995 Mar;195(3):198-9. Unique Identifier : AIDSLINE MED/95273731; Monteagudo M; Sola J; Mestre J; Conesa D
Thrombocytopenia in HIV infected patients. Prevalence and clinical spectrum.: Recenti Prog Med. 1995 Mar;86(3):103-6. Unique Identifier : AIDSLINE MED/95273754; Marroni M; Gresele P; Vezza R; Papili R; Francisci D; De Socio G; Di Candilo F; Baldelli F; Fiorio M; Longo F; et al; Istituto di Malattie Infettive, Universita, Perugia.; We studied the prevalence, clinical spectrum and epidemiologic features of thrombocytopenia among 442 (333 male, 109 female) HIV infected patients. Thrombocytopenia was defined as a platelet count
Understanding HIV1, cytokines and effective immunity: bridging the gap between cytokine regulation in vitro and in vivo [editorial]: Res Immunol. 1994 Oct-Dec;145(8-9):575-7. Unique Identifier : AIDSLINE MED/95273776; Montaner LJ
Cytokine regulation of acute and chronic HIV infection in vitro: from cell lines to primary mononuclear cells.: Res Immunol. 1994 Oct-Dec;145(8-9):578-82. Unique Identifier : AIDSLINE MED/95273777; Poli G; Kinter AL; Vicenzi E; Fauci AS; AIDS Immunopathogenesis Unit, DIBIT, San Raffaele Scientific; Institute, Milano, Italy.
Th2-mediated HIV1 virostatic state: macrophage-specific regulation in vitro.: Res Immunol. 1994 Oct-Dec;145(8-9):583-7; discussion 587-8. Unique Identifier : AIDSLINE MED/95273778; Montaner LJ; Gordon S; Sir William Dunn School of Pathology, University of Oxford, UK.
IL4 and IL10 as potent inhibitors of HIV1 replication in macrophages in vitro: a role for cytokines in the in vivo virus host range?: Res Immunol. 1994 Oct-Dec;145(8-9):588-92; discussion 592-4. Unique Identifier : AIDSLINE MED/95273779; Schuitemaker H; Department of Clinical Viro-Immunology, Central Laboratory of the; Red Cross Blood Transfusion Services, Amsterdam.
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