1995

Genetic immunization : protective immune responses, receptor therapy. [videorecording]: Bethesda, MD : BioConferences International, c1993 1 videocassette : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9442099; (Producer) Topics include T cell receptor-based therapy of autoimmune diseases; genetic immunization: generates neutralizing and protective immune responses to HIV-I; immunosuppression by blockade of the T cell costimulation; a recombination based transgenic mouse assay for genotoxicity.
[Ai tzu ping fang chih li lun yu shih chien.] Ti 1 pan.: Shang-hai : Shang-hai k'o hsueh chi shu ch'u pan she, 1989 299 p. : ill Unique Identifier : AIDSLINE CAT/9500651; Ch'eng W
AIDS : images for survival = AIDS : saengjon ul wihan imiji.: Washington, DC : Shoshin Society, c1989 1 v. (unpaged) : ill Unique Identifier : AIDSLINE CAT/9502468; Helmken C
Early medical intervention in persons infected with the AIDS virus : report.: The Hague : Gezondheidsraad, [1990] 4 leaves Unique Identifier : AIDSLINE CAT/9409970
Annual report.: Program Oakland, CA : The Program, v Unique Identifier : AIDSLINE CAT/9441331
AIDS/HIV infection and the workplace : NIDA workgroup report.: [Rockville, Md.] : Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, [1990?] vii, 36 p. : ill (DHHS publication ; no. (ADM) 90-1716) Unique Identifier : AIDSLINE CAT/9400727
Biologisen laaketieteen suuntauksia : vapaiden radikaalien, ravinnon hivenaineiden, vitamiinien, ja antioksidanttien merkitys ihmisen terveydelle : esitelmalyhennelmat.: Helsinki : Yliopistopaino, 1990 75 p Unique Identifier : AIDSLINE CAT/9405386; Antila E
A:pharmacist's guide to AIDS education.: Sacramento, CA : The Association, [c1991] vii, 178 p. : ill Unique Identifier : AIDSLINE CAT/9410672
Facts about A.I.D.S. : 100 questions and answers about the acquired immune deficiency syndrome.: Gweru [Zimbabwe] : Mambo Press, 1991 47 p. : ill Unique Identifier : AIDSLINE CAT/9410095; Foster G
PWA newsline. Issue #62 (Jan./Feb. 1991)-: New York, N.Y. : The Coalition, v Unique Identifier : AIDSLINE CAT/9439283
[Parler du SIDA avec les adolescents : guide pedagogique a l'usage des professionnels : une histoire d'amour.]: Vanves : Comite francais d'education pour la sante, [1992] 150 p (La sante en action) Unique Identifier : AIDSLINE CAT/9417988; Ferron C
[SIDA : entre la medicina y la etica.]: Buenos Aires : Ediciones Paulinas, [1992] 86 p. : ill (Coleccion Temas vivos) Unique Identifier : AIDSLINE CAT/9414812; Barazzutti L
Genetic variation of the third variable envelope region in natural HIV-1 infection.: [Amsterdam? : s.n., 1992?] 149 p. : ill Unique Identifier : AIDSLINE CAT/9405498; Wolfs TF
Challenge of AIDS. 1st ed.: New Delhi : National Book Trust, 1992 118 p. : ill (Popular science) Unique Identifier : AIDSLINE CAT/9433129; Pavri KM
HIV infection and AIDS.: Bombay : Vora Medical Publications, 1992 139 p. : ill Unique Identifier : AIDSLINE CAT/9432465; Deodhar L
[Cancer et SIDA a la lumiere de la psychanalyse.]: [France?] ; Lucien Souny, 1993 273 p. : ill Unique Identifier : AIDSLINE CAT/9418252; Herzog B
Report.: Pacific Prevention and Control of AIDS in the Pacific Manila, Philippines : Printed and distributed by Regional Office for the Western Pacific of the World Health Organization, [1993] 28 p (Report series ; no. RS/93/GE/01(FIJ)) Unique Identifier : AIDSLINE CAT/9414061
PWAC NY newsline.: New York, NY : The Coalition, v Unique Identifier : AIDSLINE CAT/9439282
[Kunst und AIDS in New York : silence=death.]: Hannover : Hannoversche AIDS-Hilfe e.V., c1993 80 p. : ill Unique Identifier : AIDSLINE CAT/9433859; Hieber L; Theising G
[Ethik, Moral, Sittlichkeit, und AIDS : eine kommentierte Bibliographie deutschsprachiger Veroffentlichungen.] 1. Aufl.: Frankfurt/Main : Mabuse Verlag, 1994 69 p (Reihe Archiv fur Sozialpolitik ; Bd. 5) Unique Identifier : AIDSLINE CAT/9437216; Dressler S
[Rein, troubles metaboliques, et infection par le VIH.]: Paris : Masson, 1994 vii, 120 p. : ill (ABC de medecine) Unique Identifier : AIDSLINE CAT/9432799; Cassuto-Viguier E
Atlas of HIV infection. 1st ed.: Chiang Mai, Thailand : Support the Children Foundation, 1994 xxiv, 228 p. : ill Unique Identifier : AIDSLINE CAT/9502481; Prakong Vithayasai
AIDS musculoskeletal manifestations.: St. Louis, Mo. : Warren H. Green, c1994 xiii, 181 p. : ill Unique Identifier : AIDSLINE CAT/9500995; Tehranzadeh J; Steinbach LS
AIDS : some workplace basics : self-instructional training.: Washington, DC : U.S. Dept. of Labor, [1994] 1 v. (various pagings) Unique Identifier : AIDSLINE CAT/9500992; Acosta L
Current directions in AIDS research : an analysis of AIDS drug and vaccine development projects at the NIH : X International AIDS Conference, Yokohama, Japan, August 1994.: [New York, N.Y.] : Gay Men's Health Crisis, c1994 35 p. : ill Unique Identifier : AIDSLINE CAT/9441253; Link D
HIV and AIDS.: Oxford, UK : Bios Scientific Publishers ; Herndon, VA : Distributors, USA and Canada, Books International, 1994 xii, 91 p. : ill (Medical perspectives series) Unique Identifier : AIDSLINE CAT/9500035; Nye KE; Parkin JM
Modern approaches to new vaccines, including prevention of AIDS.: Plainview, N.Y. : Cold Spring Harbor Laboratory Press, 1994 xix, 403 p. : ill., ports Unique Identifier : AIDSLINE CAT/9441398; Norrby E
Redefining AIDS : the dead & dispossessed.: Las Colinas [Tex.] : Monument Press, 1994 ix, 156 p. : ill (The Politics of AIDS ; v. 4) Unique Identifier : AIDSLINE CAT/9442164; Dickerson NA
WHO guidelines for standard HIV isolation procedures.: [Geneva] : World Health Organization, 1994 53 p. : ill Unique Identifier : AIDSLINE CAT/9442571
Cancer and HIV clinical nutrition pocket guide.: Boston : Jones and Bartlett Publishers, c1995 x, 209 p. : ill Unique Identifier : AIDSLINE CAT/9502389; Wilkes GM
NIH Conference on Retroviral Integrase : molecular biology and pharmacology : a novel target for the treatment of AIDS, January 19-20, 1995.: [Bethesda, Md.? : The Institute?, 1995?] 1 v. (unpaged) Unique Identifier : AIDSLINE CAT/9502489
AIDS clinical trials.: New York : Wiley-Liss, c1995 xiv, 458 p. : ill Unique Identifier : AIDSLINE CAT/9503774; Finkelstein DM; Schoenfeld DA
Radiation therapy without biopsy of AIDS-related central nervous system lymphomas (Meeting abstract).: International Congress of Radiation Oncology 1993. June 21-25, 1993, Kyoto, Japan, p. 309, 1993.. Unique Identifier : AIDSLINE ICDB/95606040; Nisce LZ; Kaufmann T; Metroka C; Dept. of Radiation Oncology, New York Hosp.-Cornell Medical; Center; The purpose of this presentation is to evaluate the role of radiation therapy in the management of lymphomas (NHL) of the CNS in the acquired immune deficiency syndrome (AIDS). Between 1986 and 1992, 18 patients, with AIDS-related CNS NHL, were seen at the New York Hospital-Cornell Medical Center. All patients were sy
Cytogenetic changes of human T-lymphotropic virus type I infected human lymphocytes transformed by carcinogen treatment (Meeting abstract).: 2nd International Conference on Gene Regulation/Oncogenesis/AIDS, September 23-30, 1993, Loutraki, Greece, p. 38, 1993.. Unique Identifier : AIDSLINE ICDB/95606698; Fukushima T; Mochizuki S; Kawamura K; Koshikawa N; Wang S; Miyauchi M; Maruyama K; Chiba Cancer Center Research Inst., Chiba, Japan; A number of chromosomal abnormalities have been documented in ATL in which human T-lymphotropic virus type I (HTLV-I) has been implicated. In order to investigate the mechanism of transformation of HTLV-I infected cells, lymphocytes from an HTLV-I seronegative normal person were infected in vitro with HTLV-I. A contin
Biological approaches to cancer treatment: biomodulation.: Biological Approaches to Cancer Treatment: Biomodulation. Mitchell MS, ed., New York, McGraw-Hill, 591 p., 1993.. Unique Identifier : AIDSLINE ICDB/95606862; Anonymous; No affiliation given; Biomodulation, the editor s term for biological response modification, extends the range of biological therapy beyond what has been generally considered immunotherapy. It includes in addition, increasing host ability to tolerate cytotoxic treatment, modifying tumor cell membrane characteristics to alter their immunoge
Medical oncology. 2nd ed.: Medical Oncology. 2nd ed. Calabresi P, Schein PS, eds. New York, McGraw-Hill, 1352 p., 1993.. Unique Identifier : AIDSLINE ICDB/95606865; Anonymous; No affiliation given; The second edition of this well-known text preserves the arrangement of the first with its 64 chapters divided into three sections on basic principles, specific neoplasms, and supportive care. Its basic objectives remain: to provide the practitioner and trainee with a single, comprehensive source of information; and t
Role of viruses in the etiology of lymphomas (Meeting abstract).: Fifth International Conference on Malignant Lymphoma, June 9-12, 1993, Lugano, Switzerland, p. 21, 1993.. Unique Identifier : AIDSLINE ICDB/95606899; Weiss L; Div. of Pathology, City of Hope Natl. Medical Center, 1500 E.; Duarte Rd., Duarte, CA 91010; Several viruses have been proposed to be involved in the etiology of non-Hodgkin s lymphomas, including human T-cell leukemia virus-1 (HTLV-1), Epstein-Barr virus (EBV) and human herpes virus-6 (HHV-6). HTLV-1 is a human retrovirus that is endemic in several regions, including the southernmost islands of
Epstein-Barr virus (EBV) latent and replicative gene expression in AIDS-related non-Hodgkin's lymphoma (NHL) and post-transplant lymphoproliferative disorders (PTLD) (Meeting abstract).: Fifth International Conference on Malignant Lymphoma, June 9-12, 1993, Lugano, Switzerland, p. 22, 1993.. Unique Identifier : AIDSLINE ICDB/95606900; Rea D; Delecluse HJ; Hamilton Dutoit SJ; Joab I; Young L; Raphael M; Centre d'Ecologie Cellulaire, Dept. of Hematology, Pitie; Salpetriere, Paris, France; NHL and PTLD arising in the setting of immunodeficiency states such as HIV infection and organ transplantation are frequently associated with EBV. Three forms of latent infection have been described in vitro. In type I latency (LMP-, EBNA2-) only EBNA1 is expressed. In type II latency (LMP+, EBNA2-), EBNA1 and LMP are
Primary CD30+ anaplastic large cell lymphoma: a distinct clinicopathologic entity (Meeting abstract).: Fifth International Conference on Malignant Lymphoma, June 9-12, 1993, Lugano, Switzerland, p. 24, 1993.. Unique Identifier : AIDSLINE ICDB/95606902; Kadin ME; Beth Israel Hosp.; The morphology of anaplastic large cell lymphoma (ALCL) is associated with a clinical syndrome of peripheral lymphadenopathy (greater than 80%) and frequent extranodal disease (greater than 40%) in children and young adults (median age less than 40 yr). Skin lesions occur in more than 20% of patients; other extranodal
Lymphokine receptors: a target for immunotherapy of lymphomas (Meeting abstract).: Fifth International Conference on Malignant Lymphoma, June 9-12, 1993, Lugano, Switzerland, p. 46, 1993.. Unique Identifier : AIDSLINE ICDB/95606931; Waldmann TA; NCI, Bethesda, MD 20892; Many lymphomas express lymphokine receptors not expressed by normal resting cells. Such receptors provide rational targets for immunotherapy. Specifically, the leukemic cells of patients with human T-cell leukemia virus I (HTLV-I)-associated ATL express the IL-2 recept
Induction of single-strand DNA breaks in cells infected with the human T-cell leukemia virus or bovine leukemia virus (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 35:A3392 1994. Unique Identifier : AIDSLINE ICDB/95605077; Philpott SM; Buehring GC; School of Public Health, Univ. of California at Berkeley,; Berkeley, CA 94720; Majone et al (Virology 193:456, 1993) recently demonstrated that human lymphocytes transiently transfected with a plasmid encoding the p40tax oncoprotein of the human T-cell leukemia virus (HTLV) are twice as likely to exhibit de novo formation of micronuclei than mock transfected cells. Experiments in our laboratory
Overview of AIDS malignancies (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 35:658 1994. Unique Identifier : AIDSLINE ICDB/95606240; Broder S; NCI, Bethesda, MD 20892; Immunostimulation and immune dysregulation are major components of the pathogenesis of AIDS-related Kaposi s sarcoma (KS). The HIV Tat protein augments both viral and host gene expression. Basic fibroblast growth factor (b-FGF), an inflammatory cytokine produced by AIDS-KS cells as well as stromal cells, promotes angi
Biological mechanisms in the pathogenesis of AIDS-associated Kaposi's sarcoma (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 35:659 1994. Unique Identifier : AIDSLINE ICDB/95606241; Ensoli B; Barillari G; Fiorelli V; Albini A; Raffeld M; Markham P; Zon G; Gallo R; Lab. of Tumor Cell Biology, NCI, Bethesda, MD 20892; Kaposi s sarcoma (KS), a rare vascular tumor affecting elderly men of Mediterranean origin (classical KS), has become the most common form of cancer in HIV-I-infected individuals, mostly homosexual men (AIDS-KS). Establishment of long-term cultures of spindle cells of vascular origin from KS lesions of AIDS patients (
Clinical aspects of AIDS-related lymphoma (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 35:660-1 1994. Unique Identifier : AIDSLINE ICDB/95606243; Levine AM; Univ. of Southern California Sch. of Medicine, Los Angeles, CA; 90033; Lymphoma is a relatively late manifestation of HIV infection, designated as an AIDS-defining condition in 1985. With prolonged survival in HIV disease, increasing numbers of patients with lymphoma are expected. Factors associated with lymphoma included very low CD4 cells (less than 50/dl) and elevated serum IL-6 level
The regulation of cell differentiation by retinoic acid (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 35:668-9 1994. Unique Identifier : AIDSLINE ICDB/95606255; Gudas LJ; Langston A; Boylan J; Hosler B; Hu L; Dept. of Pharmacology, Cornell Univ. Medical Coll., New York, NY; 10021; Retinoic acid (RA), a derivative of retinol (vitamin A), influences the proliferation and cellular differentiation of a wide variety of cell types; RA also exhibits striking effects on vertebrate development. When F9 cells differentiate, genes such as those encoding laminin B1 and collagen type IV(alpha 1) are transc
Unrestricted cytotoxicity of murine CD4 Th1 lymphocytes on heat-shocked tumor targets.: Diss Abstr Int [B]; 54(8):4091 1994. Unique Identifier : AIDSLINE ICDB/95606420; Ozdemirli M; Boston Univ.; Murine cytotoxic CD4 Th1 lymphocytes express a cell contact-dependent cytotoxicity that induces target apoptosis. This cytotoxic process was resolved into three stages comparable with those of CD8 CTL: conjugate formation/activation, lethal hit, and effector-independent target lysis. Upon activation, CD4 Th1 clones sy
Transformation potential of human insulin receptor.: Diss Abstr Int [B]; 54(8):3990 1994. Unique Identifier : AIDSLINE ICDB/95606433; Du DY; Rockefeller Univ.; The transforming potential of human insulin receptor (hIR) previously has been demonstrated by transfecting chicken embryo fibroblasts (CEFs) with 5 -truncated hIR cDNAs, which had been fused in frame to RSV gag sequences (gag-IR fusion). The investigation of the molecular basis for hIR transformation activation is th
Effect of human immunodeficiency virus infection and immunosuppression on the detection of human papillomavirus and the development of anal squamous intraepithelial lesions.: Diss Abstr Int [B]; 54(8):4100 1994. Unique Identifier : AIDSLINE ICDB/95606447; Critchlow CW; Univ. of Washington; A small pilot study was first conducted among 145 consecutive homosexual men seeking HIV serologic testing to evaluate the feasibility of potential studies of human immunodeficiency virus (HIV) infection, detection of anal human papillomavirus (HPV) and anal squamous intraepithelial neoplasia (ASIL). Anal HPV DNA was
Signal transduction complex from 13762 ascites rat mammary tumor cells: molecular cloning of a major protein and phosphorylation studies.: Diss Abstr Int [B]; 54(11):5529 1994. Unique Identifier : AIDSLINE ICDB/95606787; Juang S; Univ. of Miami; MAT-B1 and MAT-C1 sublines of the 13762 rat mammary ascites adenocarcinoma differ in their cell surface morphology, receptor mobility and xenotransplatability. These differences have been ascribed to differences in the structure and stability of the microvilli present on the surfaces of these sublines. The MAT-C1 subl
Characterization of a novel Ets transcription factor, Elf-1.: Diss Abstr Int [B]; 54(11):5537 1994. Unique Identifier : AIDSLINE ICDB/95606818; Wang C; Univ. of Michigan; In this thesis I describe the cloning and characterization of a novel Ets-related transcription factor, Elf-1. Elf-1 is expressed in cells of lymphoid lineage and is able to bind the Ets-binding site in the transcription regulatory elements of multiple T cell genes, including the
The protein determinants for RNA packaging in avian sarcoma and leukemia virus.: Diss Abstr Int [B]; 54(12):6066 1994. Unique Identifier : AIDSLINE ICDB/95607125; Sakalian M; Cornell Univ.; In all retrovirus systems studied, the leader region of the RNA contains a cis-acting sequence called Psi that is required for packaging the viral RNA genome. Since the pol and env genes are dispensable for formation of RNA-containing particles, the gag gene product must have an RNA binding domain(s) capable of recogn
Lymphoma in human immunodeficiency virus infection.: Diss Abstr Int [B]; 54(12):6127 1994. Unique Identifier : AIDSLINE ICDB/95607173; Boyle MJ; Univ. of New South Wales, Australia; A clinical series of 41 HIV-associated NHL cases was analyzed. The findings confirmed, in an Australian population many features of HIV-associated NHL reported in other countries and suggested two definable groups of lymphoma patients: One with large cell immunoblastic histology, advanced immunodeficiency and a poor s
Pyrrolidine dithiocarbamate prevents the induced expression of VCAM-1 in Kaposi's sarcoma cells (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 35:A2836 1994. Unique Identifier : AIDSLINE ICDB/95604521; Offermann MK; Medford RM; Shaw R; Emory University, Atlanta, GA 30322; Kaposi s sarcoma (KS) is a neoplasm with multifocal vascular lesions that is seen in over 20% of HIV infected individuals. Evidence suggests that products of T-lymphocytes and monocytes are major contributors to the pathogenesis of KS. Biopsies of KS lesions demonstrate high levels of expression of the cellular adhesi
AIDS-related Kaposi's sarcoma: clinical aspects (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 35:659-60 1994. Unique Identifier : AIDSLINE ICDB/95606242; Krown SE; Memorial Sloan-Kettering Cancer Center, New York, NY 10021; Although the incidence of Kaposi s sarcoma (KS) the most common neoplastic complication of HIV infection, appears to be declining with time, its prevalence remains high and appears to be growing in importance as a contributor to late morbidity and mortality in profoundly immunosuppressed HIV-infected people. Although
AIDS has an increasing diffusion within the heterosexual population [letter]: AIDS Patient Care. 1994 Jun;8(3):106. Unique Identifier : AIDSLINE AIDS/95103310; Lazzari C; Costigliola P; Di Bari MA; De Ronchi D; Volterra V; Chiodo F
Hyperbaric oxygen therapy to relieve chronic fatigue associated with HIV/AIDS [letter]: AIDS Patient Care. 1994 Jun;8(3):106-7. Unique Identifier : AIDSLINE AIDS/95103311; Reillo M; Altieri R; Neubauer R
Abbreviations in medicine. Are we shortchanging our patients and ourselves?: AIDS Patient Care. 1994 Jun;8(3):108-9. Unique Identifier : AIDSLINE AIDS/95103312; Buff DD; Department of Medicine, St. John's Episcopal Hospital, Far; Rockaway, NY.
Progressive multifocal leukoencephalopathy (PML) in two cases of cortical blindness.: AIDS Patient Care. 1994 Jun;8(3):110-3. Unique Identifier : AIDSLINE AIDS/95103313; Smith DD; Robinson MR; Scheibel SF; Valenti WM; Eskin TA; University of Rochester Medical Center, NY.
A survey of gay and bisexual men age 50 and older. AIDS related knowledge, attitude, belief, and behavior.: AIDS Patient Care. 1994 Jun;8(3):114-7. Unique Identifier : AIDSLINE AIDS/95103314; Kooperman L; Golden Gate University, San Francisco, CA.
AIDS care for the elderly. A community-based approach.: AIDS Patient Care. 1994 Jun;8(3):118-20. Unique Identifier : AIDSLINE AIDS/95103315; Garvey C; Home Health Services, Visiting Nurses and Hospice of San; Francisco, CA.
AIDS and long-term care. An examination of Florida's Medicaid incentive reimbursement program.: AIDS Patient Care. 1994 Jun;8(3):121-6. Unique Identifier : AIDSLINE AIDS/95103316; Cruise PL; School of Public Administration, Florida Atlantic University, Ft.; Lauderdale.; People living with HIV/AIDS will have a greater need for long-term care options as the disease develops into a chronic, rather than an acute, condition. Nursing homes, a major component in the long-term care continuum, traditionally have been reluctant to admit PWAs, forcing some states to adopt incentive programs to
Psychosocial considerations of HIV infection in the older adult.: AIDS Patient Care. 1994 Jun;8(3):127-9. Unique Identifier : AIDSLINE AIDS/95103317; Lavick J; Jeffrey Goodman Special Care Clinic, Los Angeles Gay and Lesbian; Community Services Center, CA.
Providing long-term care for persons with AIDS. Results from a survey of nursing homes in the United States.: AIDS Patient Care. 1994 Jun;8(3):130-7. Unique Identifier : AIDSLINE AIDS/95103318; Gentry D; Fogarty TE; Lehrman S; Group in Health Services and Policy Analysis, School of Public; Health, University of California, Berkeley.; In this pilot study, a random sample of 50 nursing homes located in each of the five U.S. cities with the highest AIDS incidence were surveyed (total N = 250) to determine: (1) the frequency of admission inquiries by, and actual admissions of PWAs, (2) the frequency of adoption of formal AIDS admission policies, (3) t
Advances in the diagnosis and treatment of Mycobacterium avium complex (MAC) disease.: AIDS Patient Care. 1994 Jun;8(3):138-40. Unique Identifier : AIDSLINE AIDS/95103319; Benson C; Section of Infectious Disease, Rush-Presbyterian-St. Luke's; Medical Center, Chicago, IL.
Using hypnotic imagery in patients with HIV disease.: AIDS Patient Care. 1994 Jun;8(3):141-3. Unique Identifier : AIDSLINE AIDS/95103320; Coulter AH
Managing early HIV infection. A Quick Reference Guide for Clinicians.: AIDS Patient Care. 1994 Jun;8(3):144-63. Unique Identifier : AIDSLINE AIDS/95103321
NDA filed for stavudine [news]: AIDS Patient Care. 1994 Jun;8(3):164. Unique Identifier : AIDSLINE AIDS/95103322
ZDV reduces maternal transmission [news]: AIDS Patient Care. 1994 Jun;8(3):164. Unique Identifier : AIDSLINE AIDS/95103323
ZDV resistance AIDS predictor [news]: AIDS Patient Care. 1994 Jun;8(3):164. Unique Identifier : AIDSLINE AIDS/95103324
Acyclovir improves survival [news]: AIDS Patient Care. 1994 Jun;8(3):165. Unique Identifier : AIDSLINE AIDS/95103325
Bactrim approved for prophylaxis [news]: AIDS Patient Care. 1994 Jun;8(3):166. Unique Identifier : AIDSLINE AIDS/95103326
Interleukin-4 tried for KS [news]: AIDS Patient Care. 1994 Jun;8(3):166-7. Unique Identifier : AIDSLINE AIDS/95103327
Aberrant alpha-interferon removed [news]: AIDS Patient Care. 1994 Jun;8(3):167. Unique Identifier : AIDSLINE AIDS/95103328
Gaminune N approved in pediatric AIDS [news]: AIDS Patient Care. 1994 Jun;8(3):167. Unique Identifier : AIDSLINE AIDS/95103329
Oxygen plus ozone inactivate HIV [news]: AIDS Patient Care. 1994 Jun;8(3):167. Unique Identifier : AIDSLINE AIDS/95103330
Beeper-sized device sounds alarm when gloves or barrier garments develop microscopic punctures [news]: AIDS Patient Care. 1994 Jun;8(3):169. Unique Identifier : AIDSLINE AIDS/95103331
AIDS and HIV information on the Internet [news]: AIDS Patient Care. 1994 Jun;8(3):170. Unique Identifier : AIDSLINE AIDS/95103332
AIDS and HIV information [news]: AIDS Patient Care. 1994 Jun;8(3):170-1. Unique Identifier : AIDSLINE AIDS/95103333
AIDS aware.: AIDS Patient Care. 1994 Jun;8(3):174-9. Unique Identifier : AIDSLINE AIDS/95103334
Salk's HIV immunogen: an immune-based therapy in human trials since 1988. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Crit Path AIDS Proj. 1994-95 Winter;(No 30):1, 20-3. Unique Identifier : AIDSLINE AIDS/95700001; Jonas Salk, the developer of the first polio vaccine, has created a therapeutic vaccine for HIV which helps the immune system fight disease progression. Salk uses inactivated HIV-1 virus combined with Incomplete Freund s Adjuvant (IFA) in the vaccine preparation. The resulting HIV-1 immunogen was first studied in 1987
Yokohama report: an activist's journal. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Crit Path AIDS Proj. 1994-95 Winter;(No 30):1, 23-4, 36. Unique Identifier : AIDSLINE AIDS/95700002; Kuromiya K; The 10th International Conference on AIDS was the first to be held in Asia. Many street activists boycotted it because of Japan s relatively small incidence of AIDS, because Japan was too expensive and excludes immigration and travel of HIV-infected individuals, and because the conference should have been held in the
Observations on Critical Path Project's fifth anniversary. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Crit Path AIDS Proj. 1994-95 Winter;(No 30):2, 4. Unique Identifier : AIDSLINE AIDS/95700004; Kuromiya K; Treatment activism, unknown five years ago, has been an important development of the AIDS epidemic. Activist pressure has pushed the government into greatly reducing the time taken to bring experimental treatments to market. For the first time in history, representatives of community-based organizations sit on scienti
Donald Abrams' marijuana study. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Crit Path AIDS Proj. 1994-95 Winter;(No 30):9-17. Unique Identifier : AIDSLINE AIDS/95700005; Donald Abrams is the principal investigator in a prospective, randomized community-based clinical trial conducted by the Community Consortium, University of California, San Francisco. He will conduct a pilot study to evaluate high-, medium- or low-potency smoked marijuana versus dronabinol in stimulating appetite and
International conference on AIDS--Yokohama. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Crit Path AIDS Proj. 1994-95 Winter;(No 30):25-6. Unique Identifier : AIDSLINE AIDS/95700007; Discussion topics ranged from treatments to products at the 10th International AIDS Conference in Yokohama. Topics covered included vaccine development; the correlation of environmental, genetic, and pathogenesis factors in long term survivors and long term nonprogressors; and Otsuka s vanarinone for treatment of AIDS
AIDS information on the Internet (Part 1 of 2). Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Crit Path AIDS Proj. 1994-95 Winter;(No 30):37-9. Unique Identifier : AIDSLINE AIDS/95700009; Critical Path intends to offer free Internet access to Critical Path BBS users in the Philadelphia area. Service providers and individuals will be able to search AIDS-related National Library of Medicine and Clinical Path databases, and will be able to engage in discussions with others in remote cities. An outline of
FDA: polyurethane condom carries 'extremely misleading' label. Food and Drug Administration. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Alert. 1995 Jan;10(1):1-4. Unique Identifier : AIDSLINE AIDS/95700020; The Avanti polyurethane condom was placed on the market bearing a misleading claim that it is effective against pregnancy, HIV (AIDS) and STDs. While the Food and Drug Administration ( FDA ) knew that the condoms were being marketed with a label that breaches regulations prohibiting the
Landmark ruling goes against surgeon. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Alert. 1995 Jan;10(1):2. Unique Identifier : AIDSLINE AIDS/95700021; A Federal judge ruled that Philadelphia s Mercy Hospital has the right to force surgeon Paul Scoles, MD, to inform his patients of his HIV-positive status in order to continue his operating privileges there. Dr. Scoles had sued the hospital, claiming that he had been discriminated against and that his practice was rui
Avanti overcomes safety concerns raised by FDA. Food and Drug Administration. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Alert. 1995 Jan;10(1):4-6. Unique Identifier : AIDSLINE AIDS/95700022; The Food and Drug Administration ( FDA ) scrutinized changes made to the Avanti polyurethane condom after it was first approved in 1989. Specifically, it questioned test results showing that the Avanti material did not biodegrade under relatively mild conditions. Certain polyurethanes c
Condom makers jockey for position in barrier warfare. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Alert. 1995 Jan;10(1):6-7. Unique Identifier : AIDSLINE AIDS/95700023; U.S. condom manufacturers are receiving competition from high quality Japanese products. However, the sale of a plastic polyurethane condom by U.S. manufacturer, London International, could potentially outsell Japanese ultra-thin condoms. The polyurethane products can be made at a uniform thinness, resulting in a more
Getting a piece of the condom pie. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Alert. 1995 Jan;10(1):8. Unique Identifier : AIDSLINE AIDS/95700024; Manufacturers of polyurethane condoms are hopeful that their thinner, more sensitive products will attract current latex users and expand the overall use of condoms. Food and Drug Administration ( FDA ) officials are concerned that polyurethane condoms will steal market share from the o
Celebrate Valentine's Day and National Condom Week. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Alert. 1995 Jan;10(1):9-10. Unique Identifier : AIDSLINE AIDS/95700025; Valentine s Day and National Condom Week are potential opportunities to publicize the use of condoms in business and social facilities. Readers are encouraged to set up information tables and condom floral arrangements to encourage media involvement and support from local nightclubs as ways to encourage the use of con
Risk of HIV transmission in dental offices 'very low'. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Alert. 1995 Jan;10(1):10-1. Unique Identifier : AIDSLINE AIDS/95700026; The results of a look-back investigation by the Centers for Disease Control and Prevention (CDC) concludes that 24 HIV-positive dental patients were not infected by their HIV-positive dentist. The retrospective investigation of a Florida dentist showed that all 24 patients had viral strains too different to be linked.
AZT studies reinforce benefits of combination. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Alert. 1995 Jan;10(1):11-2. Unique Identifier : AIDSLINE AIDS/95700027; A new anti-HIV drug, 3TC , taken with AZT is yielding exciting results. An analysis of 6,000 subjects followed for 4 years indicated that patients taking AZT in combination with
AIDS caregivers struggling with assisted suicide. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Alert. 1995 Jan;10(1):12-4. Unique Identifier : AIDSLINE AIDS/95700028; A short case study of a man who chose suicide over continuing to live with AIDS introduces this discussion of assisted suicide. Oregon is the only state where physician-assisted suicide is legal; in most other states it is explicitly illegal or the law is unclear. Rational suicide is a commonly thought about and discu
Caregivers have hand in intentional overdoses. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Alert. 1995 Jan;10(1):14-6. Unique Identifier : AIDSLINE AIDS/95700029; In a 5-year study of 136 couples, caregivers reported that 66 of the partners who had died received an increase in medication prior to death, and in 17 of these instances the increase was given intentionally to hasten death. In 80 percent of the cases where assisted suicide was discussed with the physician, the ill pa
What to do when a patient wants to die. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Alert. 1995 Jan;10(1):15. Unique Identifier : AIDSLINE AIDS/95700030; Compassion in Dying, a Seattle-based organization, offers counseling and assistance for individuals wishing to end their lives. For assistance, applicants must submit three sequential appeals in writing and a confirmed diagnosis of terminal illness by two physicians. They must have given due consideration to hospice c
Clinton gives HOPWA a reprieve, but Congress will decide program's fate. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Policy Law. 1995 Jan 13;9(24):1, 8. Unique Identifier : AIDSLINE AIDS/95700031; Patsy Fleming, Henry Cisneros, governors, mayors, and national AIDS organizations, lobbied successfully to keep the Housing Opportunities for People with AIDS (HOPWA) program in the President s fiscal 1996 budget. It is unclear how much money will be appropriated, but estimates are in the $186 million to $250 million
ADA does not protect surgeon who has HIV and wants to operate. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Policy Law. 1995 Jan 13;9(24):1-2. Unique Identifier : AIDSLINE AIDS/95700032; A U.S. District judge has ruled that a Philadelphia hospital did not violate Federal law in suspending Dr. Paul Scoles, an HIV-infected surgeon. The judge dismissed key parts of the lawsuit filed by Dr. Scoles against Mercy Health Corporation of Philadelphia, and upheld the right of the hospital to force Dr. Scoles to
Pharmacy settles privacy claim about worker's prescriptions for HIV. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Policy Law. 1995 Jan 13;9(24):2-3. Unique Identifier : AIDSLINE AIDS/95700033; As part of a plan to control healthcare costs, Southeastern Pennsylvania Transportation Authority (SEPTA) obtained prescription utilization reports from Rite Aid pharmacies. A SEPTA employee, Doe, was noted next to a prescription for an AIDS-related drug by the chief administrative officer, who then identified Doe and
Justice Department sues City of Charlotte over blocking group home. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Policy Law. 1995 Jan 13;9(24):3-4. Unique Identifier : AIDSLINE AIDS/95700034; The U.S. Department of Justice has sued the City of Charlotte, North Carolina for violating the Fair Housing Act by refusing to allow Taylor Home of Charlotte to build a group home for AIDS patients in a residential neighborhood. A city zoning ordinance allows six or more unrelated people to live together in an area z
Hospital worker with HIV tattoo sues in attempt to regain his job. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Policy Law. 1995 Jan 13;9(24):4-5. Unique Identifier : AIDSLINE AIDS/95700035; A Seattle nurse s assistant, John Baldetta, has sued the Harborview Medical Center for firing him after he refused to cover his tattoo that reads, HIV POSITIVE. Two Federal agencies, the Equal Employment Opportunity Commission (EEOC) and the Department of Health and Human Services, ruled that the dismissal was based o
Congress, courts rethinking role in preventing disability discrimination. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Policy Law. 1995 Jan 13;9(24):6-7. Unique Identifier : AIDSLINE AIDS/95700036; Congress and the judiciary may challenge the law that protects people with AIDS from discrimination in employment and public accommodations. House Speaker Newt Gingrich has proposed turning the enforcement of the Americans with Disabilities Act (ADA) to local communities. At the same time, a panel of Federal judges ha
AIDS patient drops charges against home health-care provider. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Policy Law. 1995 Jan 13;9(24):7. Unique Identifier : AIDSLINE AIDS/95700037; In 1993, Michael Alan Booth was forced to stop working because of growing fatigue related to AIDS. He discovered that his home care company, Caremark International Inc., was charging his insurance provider, Prudential Insurance Co., between $200,000 and $750,000 in excess of fair market value for drugs and services. B
Oral ganciclovir approved. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Jan 6;(No 214):1. Unique Identifier : AIDSLINE AIDS/95700038; Oral ganciclovir has been approved for marketing by the Food and Drug Administration ( FDA ), eliminating the need for daily intravenous injections for the maintenance stage of CMV retinitis treatment. (Intravenous infusions are s
FDA advisory committees meet January 26 on Salk HIV-1 immunogen. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Jan 6;(No 214):1-2. Unique Identifier : AIDSLINE AIDS/95700039; Two advisory committees of the Food and Drug Administration ( FDA ) will meet to consider future trials of the HIV-1 immunogen developed by Dr. Jonas Salk. The Immune Response Corporation has already conducted several studies of the immunogen, and has found improvement in various immuno
Women and AIDS--unexplained higher risk of death. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Jan 6;(No 214):2-3. Unique Identifier : AIDSLINE AIDS/95700040; After statistical adjustment for stage of illness, a study of 768 women and 3779 men with HIV found that the women had a one-third higher risk of death than the men, yet no higher risk of progressing to AIDS. There were also gender differences in opportunistic infections and conditions. Death was the first AIDS defini
Some vitamins associated with decreased risk of AIDS and death. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Jan 6;(No 214):3-6. Unique Identifier : AIDSLINE AIDS/95700041; There is evidence presented in a study from Johns Hopkins that dietary intake of certain vitamins is associated with survival and a substantially reduced risk of progression to AIDS. The results must be interpreted with caution for the following reasons: 1)the data are not from clinical trials but from an observationa
1995: politics. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Jan 6;(No 214):6-7. Unique Identifier : AIDSLINE AIDS/95700042; James J; A new Republican-controlled Congress may be a threat to AIDS research, care, and prevention, because of program cuts to pay for tax cuts. The Ryan White CARE Act should be reauthorized but money may not be appropriated for it, and funding from the U.S. Centers for Disease Control and Prevention (CDC) may be put into b
1995: business. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: AIDS Treat News. 1995 Jan 6;(No 214):7. Unique Identifier : AIDSLINE AIDS/95700043; Biotechnology investors suffered losses in 1994, due to depressed stock prices, making it difficult for companies to raise money to develop and test new treatments. Given this business climate, advocates for people with AIDS and other serious illnesses should be careful about pushing for laws that hold down the prices
Protease inhibitors--an update. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Crit Path AIDS Proj. 1994-94 Winter;(No 30):26-8. Unique Identifier : AIDSLINE AIDS/95700044; After five years of highly competitive work by pharmaceutical companies, a new class of drugs, called protease inhibitors , has begun human trials. HIV protease inhibitors are designed to interfere with the protease enzyme, essential for the reproduction of HIV, resu
PML--update. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Crit Path AIDS Proj. 1994-95 Winter;(No 30):28-9. Unique Identifier : AIDSLINE AIDS/95700045; Progressive multifocal leukoencephalopathy (PML) is a neurological syndrome that destroys the sheath surrounding nerve fibers in the brain. PML, an often unrecognized AIDS complication with no effective treatment, is given low priority in the national research agenda due to its low percentage of reported cases. ACTG 2
Integrase: third crucial enzyme discovered. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Crit Path AIDS Proj. 1994-95 Winter;(No 30):29-31. Unique Identifier : AIDSLINE AIDS/95700046; The three-dimensional structure of integrase, one of the enzymes that is necessary for HIV to reproduce, has been discovered at the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK). The discovery has implications for rational drug design and clinical treatment. Scientists will now be able to targe
Kombucha--toxicity alert. Clearinghouse, P.O. Box 6003, Rockville, MD 20849-6003. 800-458-5231 ext. 5023.: Crit Path AIDS Proj. 1994-94 Winter;(No 30):31-2. Unique Identifier : AIDSLINE AIDS/95700047; The Kombucha mushroom, also known as Manchurian mushroom, is a mail-order product touted to lower blood pressure and raise T-cell counts. No controlled trials have been conducted to test these claims. Aspergillus, a mold that may grow on the Kombucha mushroom, attacks the brain and may be fatal to persons with weakene
ABT-538 increases CD4 counts. [news]: Posit Aware. 1995 Jan/Feb;:4. Unique Identifier : AIDSLINE AIDS/95700089; ABT-538, a new protease inhibitor, appears to increase CD4 counts and viral load in HIV-infected persons. In a four-week placebo-controlled trial, investigators noted a CD4 count increase between 75 and 100 among participants in all four dosage groups. Dosages were either 300 mg, 400 mg, 500 mg or 600 mg, administered
Home testing kit controversy. [news]: Posit Aware. 1995 Jan/Feb;:5. Unique Identifier : AIDSLINE AIDS/95700090; The National Association of People with AIDS and other AIDS organizations have asked the Food and Drug Administration ( FDA ) to postpone action on the Johnson and Johnson (J & J) home HIV test, Confide, pending an investigation of charges that J & J illegally promoted the test while it
Triple combination superior to double combination. [news]: Posit Aware. 1995 Jan/Feb;:6. Unique Identifier : AIDSLINE AIDS/95700094; Grodeck B; Patients taking a triple combination of AZT , ddI, and nevirapine appear to have better surrogate markers than those taking the double combination of AZT and ddI, according to 241 AIDS
AIDS czar says Manhattan Project is underway. [interview by Cesar Chavez]: Posit Aware. 1995 Jan/Feb;:7. Unique Identifier : AIDSLINE AIDS/95700095; Fleming P; National AIDS Policy Director, Patricia Fleming, was recently interviewed by Positively Aware. During the interview she stated that she believes the Clinton Administration will deliver on the HIV/AIDS community s call for a Manhattan Project for AIDS. She credited Dr. William Paul (National Institutes for Health) with
Clinicians post gains against HIV-related pain.: Posit Aware. 1995 Jan/Feb;:7. Unique Identifier : AIDSLINE AIDS/95700096; McGuire S; Presenters at a November 1994 symposium on issues of pain, argued that physicians too often undertreat or fail to treat pain in people with HIV. They suggested that the reasons include misplaced fear of inducing opiate addiction and of hastening death. Speakers emphasized that people with AIDS and their physicians mus
HIV-related sinusitis: nothing to sniff at.: Posit Aware. 1995 Jan/Feb;:9. Unique Identifier : AIDSLINE AIDS/95700098; McCallister S; HIV-positive people are particularly susceptible to sinusitis, acute or chronic, and the severity of attacks increases as a person s CD4 count declines. Chronic sinusitis may, in fact, be an early manifestation of HIV infection and can even be asymptomatic. HIV-infected people should minimize the risks of contracting
On the herpes front.: Posit Aware. 1995 Jan/Feb;:10-1. Unique Identifier : AIDSLINE AIDS/95700099; Grodeck B; The virus that causes genital herpes affects 20 percent of the World s population. Among people with HIV, the incidence may be as high as 90 percent. All herpes viruses are formal candidates for the cofactor effect promoting HIV infection. People with unrecognized disease may ac
Clean shots.: Posit Aware. 1995 Jan/Feb;:12-3. Unique Identifier : AIDSLINE AIDS/95700100; Kaufman G; Jon Stuen Parker and Andrew Hoffman, son of radical Abbie Hoffman, won their battle with the City of Chicago when a judge acquitted them of charges that they knowingly broke Illinois law by participating in the illicit act of needle exchange. Illinois is one of only nine states that prohibit the distribution of steril
Prickly business. The finer points of acupuncture.: Posit Aware. 1995 Jan/Feb;:14-5. Unique Identifier : AIDSLINE AIDS/95700101; Chavez C; Acupuncture, which is gaining credibility among the Western medical establishment, is just one element of traditional Chinese medicine (TCM) being used to treat fatigue, nausea, insomnia, diarrhea, menstrual problems, and HIV-related peripheral neuropathy . Acupuncture
Insurance and acupuncture.: Posit Aware. 1995 Jan/Feb;:15. Unique Identifier : AIDSLINE AIDS/95700102; Beaubian G; Insurance coverage for acupuncture is limited. The few companies that will cover acupuncture do so only when treatments are considered medically necessary.
The health insurance jigsaw. How to line up an arrangement that will keep you covered.: Posit Aware. 1995 Jan/Feb;:16-8, 21. Unique Identifier : AIDSLINE AIDS/95700103; Thomas D; Health insurance options for people who are HIV-positive, while limited, have improved. Experts suggest strategies for HIV-positive people looking for coverage, including using unions, fraternal organizations, high-risk pools, VA insurance, green card marriages, and large employer groups and group plans offered by pro
AZT plus 3TC produces best results to date. [news]: Posit Aware. 1995 Jan/Feb;:6. Unique Identifier : AIDSLINE AIDS/95700093; Grodeck B; According to two European clinical trials, antiretroviral therapy with AZT and lamivudine ( 3TC ) shows long-lasting improvements in surrogate markers such as T-cell counts and viral lo
Lessons from Leishmania: a model for investigations of CD4+ subset differentiation.: Infect Agents Dis. 1992 Feb;1(1):33-42. Unique Identifier : AIDSLINE MED/95111859; Reiner SL; Locksley RM; Department of Medicine, University of California, San Francisco; 94143-0654.; Infection of inbred mice with Leishmania major remains the best model of human infection with visceralizing Leishmania that cause kala-azar. Immunologic investigations have correlated the outcome of disease with expansion of different subsets of CD4+ cells, designated Th1 and Th2. Although the capacity of fixed effect
Traveler's diarrhea: new perspectives.: Infect Agents Dis. 1992 Apr;1(2):114-8. Unique Identifier : AIDSLINE MED/95111863; Barry M; Department of Medicine, Yale University School of Medicine, New; Haven, CT 06504.; Despite pre-travel advice about food and water, traveler s diarrhea is the most common infectious disease problem for travelers to developing countries. New concepts of antimicrobial prophylaxis, combination treatment with antimicrobial and antimotility agents and even a new potential vaccine are reviewed.
Needle exchange or needless exchange? The state of the debate.: Infect Agents Dis. 1992 Apr;1(2):92-8. Unique Identifier : AIDSLINE MED/95111866; Kaplan EH; Yale School of Organization and Management, New Haven, CT 06520.; Needle exchange programs have been implemented in many cities around the world to slow the spread of human immunodeficiency virus (HIV) infection among injecting drug users. Whether these programs are succeeding in reducing HIV incidence is a matter of debate, as is the appropriateness of sanctioning the provision of
Rigor in clinical trials [editorial]: Infect Agents Dis. 1992 Jun;1(3):119-20. Unique Identifier : AIDSLINE MED/95111868; Whitley RJ
Pathogenesis of human herpesvirus 6 (HHV-6).: Infect Agents Dis. 1992 Jun;1(3):149-55. Unique Identifier : AIDSLINE MED/95111872; Yamanishi K; Department of Virology, Osaka University, Japan.; The newly isolated virus, human herpesvirus 6 (HHV-6), causes exanthem subitum (or roseola infantum) as the primary infection. Liver dysfunction and neurological disorders are observed during exanthem subitum. Seroepidemiological studies have shown that almost all children are infected with HHV-6 about 6-24 months aft
Late treatment of HIV infection--is it better? [published erratum appears in Infect Agents Dis 1992 Aug;1(4):225]: Infect Agents Dis. 1992 Jun;1(3):156-62. Unique Identifier : AIDSLINE MED/95111873; Hamilton JD; Medical Research Service, VA Medical Center, Durham, NC 27705.
Optimal time to initiate anti-HIV therapy: clinical decisions without definitive data.: Infect Agents Dis. 1992 Jun;1(3):163-6. Unique Identifier : AIDSLINE MED/95111874; Volberding P; AIDS Program, San Francisco General Hospital, CA 94110.
[2 cases of spontaneous pneumothorax due to acute nosocomial bilateral staphylococcal bronchopneumonia]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):145-6. Unique Identifier : AIDSLINE MED/95121832; Gnarini R; Guerriero M; Postiglione A; Smeraglia R; Conte M; Galderisi P; Soscia M; Ospedale D. Cotugno, Napoli.
[Imipenem-cilastatin in nosocomial infections in HIV+ patients]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):191-2. Unique Identifier : AIDSLINE MED/95121851; Pagano G; Repetto T; Ferrazin A; Canessa A; Carrega G; I Clinica Malattie Infettiva, Universita degli Studi, Genova.
[AZT induces remission of chronic active C virus hepatitis in subjects with HIV-1 infection]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):193-4. Unique Identifier : AIDSLINE MED/95121852; Garofano T; Vento S; Di Perri G; Concia E; Bassetti D; Divisione Malattie Infettive, Ospedale A. Pugliese, Catanzaro.
[Resistance to antitubercular agents in mycobacterial infections in HIV-positive patients]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):195-6. Unique Identifier : AIDSLINE MED/95121853; Dal Conte I; Quirino T; Orlando G; Infuso A; Tocalli L; Dedivitis G; Argenteri B; I Divisione Malattie Infettive, Ospedale, L. Sacco, Milano.
[Anaerobes as opportunistic agents in HIV infections]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):197-8. Unique Identifier : AIDSLINE MED/95121854; Malena M; Mazzi R; Danzi MC; Luzzati R; Concia E; Bassetti D; Istituto di Malattie Infettive, Universita degli Studi, Verona.
[Primary treatment of cryptococcosis in AIDS: itraconazole in single dose or combined with 5-fluorocytosine]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):199-200. Unique Identifier : AIDSLINE MED/95121855; Fasan M; Gubertini G; Cargnel A; Vigevani GM; Rizzardini G; Capetti A; Vaglia A; Grancini A; Malaspina C; Tortorano AM; et al; II Divisione Malattie Infettive, Ospedale L. Sacco, Milano.
[Carcinoma of the anal canal in HIV+ subjects. Description of a case and therapeutic strategy]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):207-8. Unique Identifier : AIDSLINE MED/95121858; Catalano G; Della Vittoria Scarpati M; De Vita F; Rippa A; Gattoni A; Dodaro C; Renda A; Servizio di Oncologia Medica, I Facolta di Medicina e Chirurgia,; Universita degli Studi, Napoli.
[Pathologic findings in migrants from developing countries: the experience of the S. Chiara di Palermo ambulatory polyclinic]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):7-9. Unique Identifier : AIDSLINE MED/95121877; Mansueto S; Poliambulatorio S. Chiara di Palermo, Istituto Italiano di; Medicina delle Migrazioni Universita degli Studi di Palermo.; Immigrants are frequently considered as carriers of unknown and/or exotic diseases. On the basis of data collected by a working unit of Palermo, specifically devoted to the immigrants, we may affirm that the more frequent medical problems (67.1%) were of internal origin (especially gastro-enterologic, rheumatologic an
[Antineoplastic chemotherapy in patients with HIV infection]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):79-82. Unique Identifier : AIDSLINE MED/95121880; Spina M; Tirelli U; Monfardini S; Divisione di Oncologia Medica, Centro di Riferimento Oncologico,; Aviano, PN.
[Possibilities of chemoprophylaxis and chemotherapy in protozoan opportunistic infections]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):83-5. Unique Identifier : AIDSLINE MED/95121881; Ortona L; Antinori A; Clinica Malattie Infettive, Universita Cattolica Sacro Cuore,; Roma.
[Opportunistic infections and tumors in AIDS]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):87-9. Unique Identifier : AIDSLINE MED/95121882; Lazzarin A; Danise A; D'Arminio-Monforte A; Tambussi G; Moroni M; Clinica delle Malattie Infettive, Universita degli Studi di; Milano.
[Clinico-therapeutic features of pulmonary pneumocystis in the patient with AIDS]: G Ital Chemioter. 1991 Jan-Dec;38(1-3):91-4. Unique Identifier : AIDSLINE MED/95121883; Libanore M; Bicocchi R; Pantaleoni M; Bertoni R; Sighinolfi L; Carradori S; Montanari P; Guidetti B; Bedetti A; Ghinelli F; Divisione Malattie Infettive, Arcispedale S. Anna, Ferrara.
Fungal plasma membrane proton pumps as promising new antifungal targets.: Crit Rev Microbiol. 1994;20(3):209-23. Unique Identifier : AIDSLINE GENBANK/X65738; Monk BC; Perlin DS; Department of Oral Biology and Oral Pathology, Faculty of; Dentistry, University of Otago, Dunedin, New Zealand.; Fungi are widely dispersed in nature and frequently appear as pathogens in the animal and plant kingdoms. The incidence of opportunistic fungal infections in humans has increased due to the human immunodeficiency virus and the application of modern medical approaches that subvert natural protective barriers to infecti
[The relationship of the immunodeficiency virus, AIDS and tuberculosis in New York City]: Bol Oficina Sanit Panam. 1994 Nov;117(5):438-52. Unique Identifier : AIDSLINE MED/95101141; Fujiwara PI; Huberman R; Servicio de Control de la Tuberculosis, Departamento de Salud de; la Ciudad de Nueva York.
Programmed cell death (apoptosis) and cell survival regulation: relevance to AIDS and cancer [editorial]: AIDS. 1994 Sep;8(9):1197-213. Unique Identifier : AIDSLINE MED/95101155; Ameisen JC
Prostitution and HIV: what do we know and where might research be targeted in the future? [editorial] [see comments]: AIDS. 1994 Sep;8(9):1215-26. Unique Identifier : AIDSLINE MED/95101156; McKeganey NP
Viral RNA-binding activity of HIV-2 nucleocapsid protein is inhibited by a synthetic peptide containing the first zinc finger motif of HIV-2.: AIDS. 1994 Sep;8(9):1227-35. Unique Identifier : AIDSLINE MED/95101157; Komatsu H; Tozawa H; Department of Immunology, School of Hygienic Sciences, Kitasato; University, Sagamihara, Japan.; OBJECTIVE: To analyze the antigenic structure and viral RNA-binding activity of HIV-2GH-1 nucleocapsid protein (NC). METHODS: Five synthetic peptides corresponding to hydrophilic regions of HIV-2GH-1 NC were prepared. The reactivity of rabbit antisera directed against these synthetic peptides was examined by Western b
Development of malabsorption and nutritional complications in simian immunodeficiency virus-infected rhesus macaques.: AIDS. 1994 Sep;8(9):1245-56. Unique Identifier : AIDSLINE MED/95101159; Stone JD; Heise CC; Miller CJ; Halsted CH; Dandekar S; Department of Internal Medicine, University of California, Davis; 95616.; OBJECTIVE: To assess the development and cause of malabsorption in rhesus macaques following experimental simian immunodeficiency virus (SIV) infection and to evaluate its impact on nutritional status. DESIGN: Clinical malabsorption tests and serial jejunal aspirates and biopsies were obtained from nine SIV-infected a
Serological survey of HIV-1, HIV-2 and human T-cell leukemia virus type 1 for suspected AIDS cases in Ghana.: AIDS. 1994 Sep;8(9):1257-61. Unique Identifier : AIDSLINE MED/95101160; Hishida O; Ayisi NK; Aidoo M; Brandful J; Ampofo W; Osei-Kwasi M; Ido E; Igarashi T; Takehisa J; Miura T; et al; Research Center for Immunodeficiency Virus, Kyoto University,; Japan.; OBJECTIVE: To determine seroprevalence among suspected AIDS patients in Ghana in relation to clinical manifestations. MATERIALS AND METHODS: Blood samples and medical records were collected from 290 Ghanaian patients with suspected AIDS in 1990 and 1992. Seroprevalence of HIV-1, HIV
Detection of subclinical Mycobacterium avium intracellulare complex infection in immunodeficient HIV-infected patients treated with zidovudine.: AIDS. 1994 Sep;8(9):1263-9. Unique Identifier : AIDSLINE MED/95101161; Mallal SA; James IR; French MA; Department of Clinical Immunology, Royal Perth Hospital,; Australia.; OBJECTIVE: To test the hypothesis that subclinical Mycobacterium avium intracellulare complex (MAC) infection may result in the development of a tuberculin response in immunodeficient HIV-infected individuals treated with zidovudine. DESIGN: Longitudinal, observational study. SETTING: The Western Australian HIV Cohort
Pulmonary cryptococcosis associated with HIV-1 infection in Rwanda: a retrospective study of 37 cases.: AIDS. 1994 Sep;8(9):1271-6. Unique Identifier : AIDSLINE MED/95101162; Batungwanayo J; Taelman H; Bogaerts J; Allen S; Lucas S; Kagame A; Clerinx J; Montane J; Saraux A; Muhlberger F; et al; Department of Internal Medicine, Centre Hospitalier de Kigali,; Rwanda.; OBJECTIVES: To study the demographic, clinical, radiographic and diagnostic features, the clinical course and therapeutic response of pulmonary cryptococcosis in HIV-1-infected patients. DESIGN: Retrospective review. SETTING: The Department of Medicine of an urban reference hospital in Central Africa. METHODS: All the
Anti-A60 immunoglobulin G in the serodiagnosis of tuberculosis in HIV-seropositive and seronegative patients.: AIDS. 1994 Sep;8(9):1277-80. Unique Identifier : AIDSLINE MED/95101163; Pouthier F; Perriens JH; Mukadi Y; Kayembe T; St Louis ME; Brown C; Prignot J; Catholic University of Louvain, Mont Godinne, Belgium.; OBJECTIVE: A60 is a high molecular weight mycobacterial antigen complex. The detection of immunoglobulin (Ig) G antibodies to A60 has been advocated as a reasonably sensitive and specific test for active tuberculosis (TB). We aimed to compare the sensitivity of this test among HIV-seropositive and HIV-seronegative pat
Response to hepatitis B immunization by infants exposed to HIV.: AIDS. 1994 Sep;8(9):1281-4. Unique Identifier : AIDSLINE MED/95101164; Rutstein RM; Rudy B; Codispoti C; Watson B; Division of General Pediatrics, Children's Hospital of; Philadelphia, PA 19104.; OBJECTIVE: To assess the antibody response to hepatitis B immunization in HIV-infected and uninfected infants. DESIGN: Cohort, comparing hepatitis B surface-antibody responses of HIV-infected infants with HIV-exposed but uninfected infants. SETTING: Urban children s hospital outpatient clinic for families with HIV-inf
Preparation for phase III HIV vaccine efficacy trials: methods for the determination of HIV incidence.: AIDS. 1994 Sep;8(9):1285-91. Unique Identifier : AIDSLINE MED/95101165; Heyward WL; Osmanov S; Saba J; Esparza J; Belsey E; Stoneburner R; Kaldor J; Smith PG; Vaccine Development Unit, World Health Organization, Geneva,; Switzerland.; OBJECTIVE: Accurate estimates of HIV incidence that reflect the effect of non-vaccine interventions (education, counselling, condom promotion, and possibly sexually transmitted disease treatment) and that may be provided in a Phase III vaccine efficacy trial, are needed so that vaccine trial population sample sizes ca
A prospective population-based study of HIV perinatal transmission.: AIDS. 1994 Sep;8(9):1293-8. Unique Identifier : AIDSLINE MED/95101166; Nesheim SR; Lindsay M; Sawyer MK; Mancao M; Lee FK; Shaffer N; Jones D; Slade BA; Ou CY; Nahmias A; Department of Pediatrics, Emory University School of Medicine,; Atlanta, Georgia 30303.; OBJECTIVE: To estimate the perinatal HIV transmission rate and describe the natural history of infant HIV infection in a situation in which HIV status is known in more than 95% of delivering women. DESIGN: A cohort of HIV-exposed infants born between 7 July 1987 and 30 June 1990, whose mothers were identified by routi
CD4 lymphocyte count as a determinant of the time from HIV seroconversion to AIDS and death from AIDS: evidence from the Italian Seroconversion Study.: AIDS. 1994 Sep;8(9):1299-305. Unique Identifier : AIDSLINE MED/95101167; Phillips AN; Pezzotti P; Lepri AC; Rezza G; Centro Operativo AIDS, Istituto Superiore di Sanita, Rome, Italy.; OBJECTIVES: It is well established that a low CD4 lymphocyte count is strongly associated with an increased risk of AIDS in HIV infection. We attempted to determine whether the link is sufficiently strong that the wide inter-person variability in times from HIV infection to AIDS can be explained solely by differences
Survival in HIV infection: do sex and category of transmission matter? Swiss HIV Cohort Study.: AIDS. 1994 Sep;8(9):1307-13. Unique Identifier : AIDSLINE MED/95101168; von Overbeck J; Egger M; Smith GD; Schoep M; Ledergerber B; Furrer H; Malinverni R; Medical Policlinic, University of Berne, Switzerland.; OBJECTIVE: To examine survival differences in HIV-infected individuals between the sexes and the categories of transmission. PATIENTS AND SETTING: Subjects assumed to have been infected by injecting drug use, by male homosexual contact or by heterosexual contact and enrolled in the Swiss HIV Cohort Study, a national m
Knowledge, attitudes and behaviour among HIV-positive and HIV-negative clients of a confidential HIV counselling and testing centre in Thailand.: AIDS. 1994 Sep;8(9):1315-9. Unique Identifier : AIDSLINE MED/95101169; Phanuphak P; Muller O; Sarangbin S; Sittitrai W; Thai Red Cross Society, Program on AIDS, Bangkok.; OBJECTIVE: To describe the clients, operation and impact of an Asian public HIV counselling and testing centre. DESIGN AND SETTING: Analysis of samples from clients attending the Thai Red Cross Anonymous Clinic (TRC-AC) in Bangkok, Thailand in 1993. SUBJECTS: HIV-positive and HIV
High risk sexual behavior and alcohol consumption among bar-going gay men.: AIDS. 1994 Sep;8(9):1321-4. Unique Identifier : AIDSLINE MED/95101170; Perry MJ; Solomon LJ; Winett RA; Kelly JA; Roffman RA; Desiderato LL; Kalichman SC; Sikkema KJ; Norman AD; Short B; et al; Office of Health Promotion Research, University of Vermont,; Burlington 05401.; OBJECTIVES: To determine whether alcohol use prior to sexual behavior influenced the occurrence of unprotected anal intercourse among bar-going gay men. METHODS: Anonymous AIDS behavioral risk surveys were administered to men entering gay bars in 16 cities on three nights in February 1993 in six states in the
Detection and biologic characterization of infectious HIV-1 in semen of seropositive men.: AIDS. 1994 Sep;8(9):1325-9. Unique Identifier : AIDSLINE MED/95101171; Vernazza PL; Eron JJ; Cohen MS; van der Horst CM; Troiani L; Fiscus SA; Department of Medicine, University of North Carolina, Chapel; Hill.; OBJECTIVE: Factors that influence the infectivity of an individual and the impact of antiviral treatment on infectivity are not well defined. This study investigated the value of a sensitive method for detecting infectious HIV in semen for use as a marker for infectivity. DESIGN: A cross-sectional study of infectious
Mapping a social network of heterosexuals at high risk for HIV infection.: AIDS. 1994 Sep;8(9):1331-6. Unique Identifier : AIDSLINE MED/95101172; Woodhouse DE; Rothenberg RB; Potterat JJ; Darrow WW; Muth SQ; Klovdahl AS; Zimmerman HP; Rogers HL; Maldonado TS; Muth JB; et al; El Paso County Department of Health and Environment, Colorado; Springs.; OBJECTIVE: To determine how heterosexuals at risk for HIV infection interconnect in social networks and how such relationships affect HIV transmission. DESIGN: Cross-sectional study with face-to-face interviews to ascertain sociosexual connections; serologic testing. PARTICIPANTS: Prostitute women (n = 133), their pay
HIV-1 infection among women of reproductive age in a rural district in Malawi.: AIDS. 1994 Sep;8(9):1337-40. Unique Identifier : AIDSLINE MED/95101173; Slutsker L; Cabeza J; Wirima JJ; Steketee RW; Division of Parasitic Diseases, Centers for Disease Control and; Prevention, Atlanta, Georgia 30333.; OBJECTIVES: To determine HIV-1 seroprevalence in pregnant women attending antenatal clinics in a rural district in Malawi , and to estimate the rate of HIV-1 infection in the district among women of reproductive age. DESIGN AND SETTING: Cross-sectional survey conducted from 1987 to
HIV testing, HIV infection and associated risk factors among inmates in south-eastern French prisons.: AIDS. 1994 Sep;8(9):1341-4. Unique Identifier : AIDSLINE MED/95101174; Rotily M; Galinier-Pujol A; Obadia Y; Moatti JP; Toubiana P; Vernay-Vaisse C; Gastaut JA; South-Eastern France Regional Centre for Disease Control,; Marseille.; OBJECTIVES: To estimate HIV seroprevalence in the two main remand and short-stay prisons of south-eastern France and to gather linked anonymous risk-factor information. SETTING: Baumettes prison, Marseille, France between 16 November and 21 December 1992. PARTICIPANTS: Using a self
Inside methodology: HIV surveillance in prisons [editorial]: AIDS. 1994 Sep;8(9):1345-6. Unique Identifier : AIDSLINE MED/95101175; Bird AG; Gore SM
GalCer, CD26 and HIV infection of intestinal epithelial cells [letter]: AIDS. 1994 Sep;8(9):1347-8. Unique Identifier : AIDSLINE MED/95101176; Fantini J; Yahi N; Delezay O; Gonzalez-Scarano F
CD26 is not required for infection of the lymphoma cell line C8166 with HIV-1 [letter]: AIDS. 1994 Sep;8(9):1348-9. Unique Identifier : AIDSLINE MED/95101177; Werner A; Mattern T; Ulmer AJ; Flad HD; Kurth R; Baier M
Cell surface expression of CD26 does not correlate with susceptibility to immunodeficiency viruses [letter]: AIDS. 1994 Sep;8(9):1349-50. Unique Identifier : AIDSLINE MED/95101178; West WH; Stott CJ
Transient insulin-dependent diabetes mellitus in an HIV-infected patient receiving didanosine [letter]: AIDS. 1994 Sep;8(9):1351. Unique Identifier : AIDSLINE MED/95101179; Vittecoq D; Zucman D; Auperin I; Passeron J
Peripheral neuropathy associated with cryoglobulinaemia but not related to hepatitis C virus in an HIV-infected patient [letter]: AIDS. 1994 Sep;8(9):1351-2. Unique Identifier : AIDSLINE MED/95101180; Le Lostec Z; Fegueux S; Vitale C; Geoffroy O; Bleton F; Mornet P
Changes in HIV seroprevalence among blood donors in Benin City, Nigeria [letter]: AIDS. 1994 Sep;8(9):1352-4. Unique Identifier : AIDSLINE MED/95101181; Offor E; Okafor L; Osunde J
Patients' attitudes to zidovudine: the influence of the Concorde trial and the media [letter]: AIDS. 1994 Sep;8(9):1354-5. Unique Identifier : AIDSLINE MED/95101182; Schroeder K; Barton SE
Increased p43-isoferritin in Ethiopian immigrants in Israel--a marker for immune activation [letter]: AIDS. 1994 Sep;8(9):1355-6. Unique Identifier : AIDSLINE MED/95101183; Moroz C; Weisman Z; Kalinkovich A; Bentwich Z
A case of rhombencephalitis with isolation of cytomegalovirus and Mycobacterium avium complex in a woman with AIDS [letter]: AIDS. 1994 Sep;8(9):1356-7. Unique Identifier : AIDSLINE MED/95101184; Duong M; Piroth L; Chavanet P; Combernoux A; Grappin M; Portier H
Laryngeal tuberculosis. A cause of stridor in children.: Arch Otolaryngol Head Neck Surg. 1995 Jan;121(1):109-12. Unique Identifier : AIDSLINE MED/95101218; Ramadan HH; Wax MK; Department of Otolaryngology-Head and Neck Surgery, West Virginia; University, Morgantown.; The number of tuberculosis (TB) cases reported in the United States has been on the decline for the last three decades. This trend has been dramatically reversed in the past few years, largely owing to the human immunodeficiency virus epidemic. Laryngeal TB, while well recognized in th
Socioeconomic differences among people with AIDS: results from a Multistate Surveillance Project.: Am J Prev Med. 1994 Jul-Aug;10(4):217-22. Unique Identifier : AIDSLINE MED/95101272; Diaz T; Chu SY; Buehler JW; Boyd D; Checko PJ; Conti L; Davidson AJ; Hermann P; Herr M; Levy A; et al; Centers for Disease Control and Prevention, Division of HIV/AIDS,; Atlanta, GA 30333.; To characterize the socioeconomic status of persons with acquired immunodeficiency syndrome (AIDS), 11 U.S. state and city health departments interviewed 2,898 persons > or = 18 years of age reported with AIDS between June 1, 1990, and January 31, 1993. Among men who have sex with men, white men reported the lowest pe
Murder and cover-up could explain the Florida dental AIDS mystery [see comments]: Br Dent J. 1994 Dec 10-24;177(11-12):423-7. Unique Identifier : AIDSLINE MED/95101364; Horowitz LG; Tetrahedron, Inc., Rockport, Massachusetts.; This article reconsiders the murder theory regarding the transmission of the human immunodeficiency virus (HIV) from Dr David J. Acer to at least six dental patients which was initially dismissed by American investigators from the Centers for Disease Control and Prevention (CDC) and Florida Health and Rehabilitative S
Suppression of cytokine production by supernatants from CD8+ lymphocytes activated by mycobacterial fractions: the role of interleukins 4 and 6.: Biotherapy. 1993-94;7(2):125-36. Unique Identifier : AIDSLINE MED/95101408; Wadee AA; Sussman G; Kuschke RH; Reddy SG; Department of Immunology, School of Pathology of the University; of the Witwatersrand, Johannesburg, RSA.; Supernatants derived from CD8+ lymphocytes treated with mycobacterial components, or the partially purified carbohydrates from these supernatants, increased the production of IL-4 and IL-6 by mononuclear cells. The addition of anti-IL4 or anti-IL6 antibodies to LPS stimulated MN cells incubated with supernatants from
Recovery of T-lymphocytes for adoptive immunotherapy by lymphapheresis of HIV-infected patients without alterations of virological, immunological or clinical parameters.: Br J Haematol. 1994 Sep;88(1):46-51. Unique Identifier : AIDSLINE MED/95101479; van Lunzen J; Schmitz J; Dengler K; Schmidt L; Schmitz H; Dietrich M; Clinical Medicine Section, Bernhard-Nocht-Institute for Tropical; Medicine, Hamburg, Germany.; We performed repeated continuous flow cytaphereses (CFC) on 13 asymptomatic HIV-1-infected patients to study the feasibility of cell separation procedures to recover high yields of peripheral blood T-lymphocytes for adoptive immunotherapy in HIV-infected patients and to determine immunological and virological alterati
Recombinant human immunodeficiency virus type-1 (HIV-1) Tat protein sequentially up-regulates IL-6 and TGF-beta 1 mRNA expression and protein synthesis in peripheral blood monocytes.: Br J Haematol. 1994 Oct;88(2):261-7. Unique Identifier : AIDSLINE MED/95101493; Gibellini D; Zauli G; Re MC; Milani D; Furlini G; Caramelli E; Capitani S; La Placa M; Institute of Microbiology, University of Bologna, Italy.; In this study we evaluated the effect of human immunodeficiency virus type 1 (HIV-1) recombinant Tat protein on mRNA expression and protein synthesis of two inflammatory cytokines-interleukin-6 (IL-6) and transforming growth factor-beta 1 (TGF-beta 1)-by peripheral blood (PB) monocytes. Whereas maximal levels of IL-6
HCV RNA levels and HIV infection: evidence for a viral interaction in haemophilic patients.: Br J Haematol. 1994 Oct;88(2):397-9. Unique Identifier : AIDSLINE MED/95101515; Telfer PT; Brown D; Devereux H; Lee CA; DuSheiko GM; Department of Haematology, Royal Free Hospital and School of; Medicine, London.; In order to investigate a possible interaction between HIV and HCV infections, we compared HCV RNA levels in 29 matched pairs of haemophilic patients seropositive for HCV and serodiscordant for HIV. Levels were assayed using the new Chiron Quantiplex bDNA assay and were found to be significantly higher in HIV seroposi
Infection of donor lymphocytes with human T lymphotrophic virus type 1 (HTLV-I) following allogeneic bone marrow transplantation for HTLV-I positive adult T-cell leukaemia [see comments]: Br J Haematol. 1994 Oct;88(2):403-5. Unique Identifier : AIDSLINE MED/95101517; Ljungman P; Lawler M; Asjo B; Bogdanovic G; Karlsson K; Malm C; McCann SR; Ringden O; Gahrton G; Department of Medicine, Huddinge University Hospital, Sweden.; Human T lymphotrophic virus type 1 (HTLV-I) associated leukaemia has a poor prognosis even with chemotherapy. We describe a patient with adult T-cell leukaemia treated with allogeneic bone marrow transplantation from an HTLV-I negative identical sibling donor. During follow-up after bone marrow transplantation, HTLV-I
CD30-positive lymphoma in human T-cell leukaemia virus type 1 carrier without monoclonal integration of HTLV-1.: Br J Haematol. 1994 Oct;88(2):419-20. Unique Identifier : AIDSLINE MED/95101522; Hori M; Mitsuhashi S; Kobayashi T; Nagasawa T; Mori N; Miwa M; Abe T; Division of Haematology, University of Tsukuba, Ibaraki, Japan.; CD30, Ki-1 antigen, an activated T-cell antigen, is a member of the nerve growth factor receptor family. This antigen is expressed on the lymphoma cells of some adult T-cell leukaemia/lymphoma (ATL/L) patients and some patients with Epstein-Barr virus infection. CD30-positive large cell cutaneous T-cell lymphomas occa
The African AIDS case definition and HIV serology in medical in-patients at Komfo Anokye Teaching Hospital, Kumasi, Ghana.: West Afr J Med. 1994 Apr-Jun;13(2):98-101. Unique Identifier : AIDSLINE MED/95101564; Ankrah TC; Roberts MA; Antwi P; Atubrah MP; Bawuah PP; Kotoh S; Acheampong JW; Wood JG; Boateng KA; Mingle JA; Department of Medicine, University of Science and Technology,; Kumasi, Ghana.; In 914 consecutive medical admissions to Komfo Anokye Teaching Hospital, the prevalence of infection with Human Immunodeficiency Virus type I (HIV-I) and Human Immunodeficiency Virus type 2 (HIV-2) was 12.6%. The prevalence in females was twice that found in males. The infection rate was maximum in the age group 25-29
Retinal findings in Malawian patients with AIDS.: Br J Ophthalmol. 1994 Oct;78(10):757-9. Unique Identifier : AIDSLINE MED/95101580; Lewallen S; Kumwenda J; Maher D; Harries AD; International Eye Foundation, Blantyre, Malawi.; The purpose of this study was to determine the prevalence of retinal disease in a group of patients with AIDS in Malawi . Indirect ophthalmoscopy was performed on 99 patients with AIDS who were admitted consecutively to a medical ward at a central hospital. Necrotising retinitis was
3-Aminobenzamide enhances dexamethasone-mediated mouse thymocyte depletion in vivo: implication for a role of poly ADP-ribosylation in the negative selection of immature thymocytes.: Biochim Biophys Acta. 1994 Dec 15;1201(3):516-22. Unique Identifier : AIDSLINE MED/95101720; Hoshino J; Koeppel C; Westhauser E; Robert Koch-Institute, Biochemistry Department, Berlin, Germany.; 3-Aminobenzamide (3-ABAm), an inhibitor of poly ADP-ribosylation, was here found to remarkably enhance the dexamethasone (Dex)-mediated depletion of total mouse thymocytes within 24 h post-injection, when given i.p. in combination with Dex. After treatment the total thymocytes were fractionated by Percoll gradient cen
Photo quiz. Oriental sore (old world cutaneous leishmaniasis).: Clin Infect Dis. 1994 Oct;19(4):667, 787-8. Unique Identifier : AIDSLINE MED/95101885; Ghigliotti G; Sementa AR; De Marchi R; Divisione di Dermatologia, Ospedale S. Martino, Genoa, Italy.
Predicting Mycobacterium avium complex bacteremia in patients infected with human immunodeficiency virus: a prospectively validated model [see comments]: Clin Infect Dis. 1994 Oct;19(4):668-74. Unique Identifier : AIDSLINE MED/95101886; Chin DP; Reingold AL; Horsburgh CR Jr; Yajko DM; Hadley WK; Elkin EP; Stone EN; Simon EM; Gonzalez PC; Ostroff SM; et al; Medical Service, San Francisco General Hospital Medical Center,; California.; In cases of advanced infection with human immunodeficiency virus, mycobacterial blood cultures are frequently used to diagnose disseminated infection with the Mycobacterium avium complex (MAC). However, no prospectively validated guidelines exist for the use of such cultures. In this study, a two-part model for predic
The clinical application of prediction models in medicine--predicting Mycobacterium avium complex bacteremia [editorial]: Clin Infect Dis. 1994 Oct;19(4):675-6. Unique Identifier : AIDSLINE MED/95101887; Wenger NS; Shapiro MF
Clinically significant mucosal candidiasis resistant to fluconazole treatment in patients with AIDS.: Clin Infect Dis. 1994 Oct;19(4):684-6. Unique Identifier : AIDSLINE MED/95101889; Newman SL; Flanigan TP; Fisher A; Rinaldi MG; Stein M; Vigilante K; Brown University, AIDS Program, Providence, Rhode Island.; Eight cases of severe mucosal candidiasis in patients with AIDS who were taking fluconazole at a dosage of 400-800 mg/d are described. Candida albicans alone or in conjunction with Torulopsis glabrata or Candida stellatoidea was isolated from each patient. In vitro susceptibility testing demonstrated resistance to flu
Azole-resistant Candida albicans: report of two cases of resistance to fluconazole and review.: Clin Infect Dis. 1994 Oct;19(4):687-92. Unique Identifier : AIDSLINE MED/95101890; White A; Goetz MB; Department of Medicine, Sepulveda Veterans Affairs Medical; Center, California 91343.; We report the course of oropharyngeal infection by Candida albicans that was refractory to treatment with fluconazole in two patients infected by the human immunodeficiency virus (HIV). We also review the epidemiology of C. albicans with decreased in vitro and in vivo susceptibility to azole antifungal agents, the sig
Fluconazole combined with flucytosine for treatment of cryptococcal meningitis in patients with AIDS.: Clin Infect Dis. 1994 Oct;19(4):741-5. Unique Identifier : AIDSLINE MED/95101898; Larsen RA; Bozzette SA; Jones BE; Haghighat D; Leal MA; Forthal D; Bauer M; Tilles JG; McCutchan JA; Leedom JM; Los Angeles County-University of Southern California Medical; Center.; Treatment of cryptococcal meningitis with amphotericin B or fluconazole is often unsuccessful; in only 35%-40% of cases do CSF cultures become negative by 10 weeks after initiation of such therapy. We conducted a prospective, open-label clinical trial involving persons with AIDS to determine whether the rate of clinic
Lytic vertebral lesions: an unusual manifestation of AIDS-associated Kaposi's sarcoma.: Clin Infect Dis. 1994 Oct;19(4):751-5. Unique Identifier : AIDSLINE MED/95101900; Isenbarger DW; Aronson NE; Department of Medicine, Walter Reed Army Medical Center,; Washington, DC 20307-5000.; The differential diagnosis of neovascular skin lesions in patients with AIDS includes Kaposi s sarcoma and bacillary angiomatosis . It has been suggested that the radiographic presence of lytic bone lesions in association with these skin lesions supports a diagnosis of bacilla
Haemophilus influenzae epididymo-orchitis and bacteremia in a man infected with the human immunodeficiency virus.: Clin Infect Dis. 1994 Oct;19(4):768-9. Unique Identifier : AIDSLINE MED/95101904; Cross JT Jr; Davidson KW; Bradsher RW Jr; Department of Medicine, University of Arkansas for Medical; Sciences, Little Rock.; Haemophilus influenzae is a major bacterial pathogen in patients infected with the human immunodeficiency virus (HIV), although most infections with this organism occur in the respiratory tract. We describe an adult with HIV infection who presented with epididymo-orchitis due to H. influenzae. Eleven prior cases of H.
Transient exacerbation of tuberculous lymphadenitis during chemotherapy in patients with AIDS.: Clin Infect Dis. 1994 Oct;19(4):774-6. Unique Identifier : AIDSLINE MED/95101906; Hill AR; Mateo F; Hudak A; Pulmonary Medicine Division, SUNY Health Science Center, New York; 11203.; We describe three men with disseminated, drug-sensitive tuberculosis and advanced human immunodeficiency virus disease (CD4+ lymphocyte count,
Clinical significance of primary vs. secondary bacteremia due to nontyphoid Salmonella in patients without AIDS.: Clin Infect Dis. 1994 Oct;19(4):777-80. Unique Identifier : AIDSLINE MED/95101907; Ramos JM; Garcia-Corbeira P; Aguado JM; Arjona R; Ales JM; Soriano F; Department of Medical Microbiology, Fundacion Jimenez Diaz,; Universidad Autonoma, Madrid, Spain.; We retrospectively reviewed the charts of 51 patients with primary nontyphoid salmonella (NTS) bacteremia who did not have AIDS and who had no history of gastroenteritis and no other identified source of infection. We compared these patients with 58 patients who developed secondary NTS bacteremia following an episode
Paranasal sinus infection due to atypical mycobacteria in two patients with AIDS.: Clin Infect Dis. 1994 Oct;19(4):789-91. Unique Identifier : AIDSLINE MED/95101910; Naguib MT; Byers JM; Slater LN; Department of Medicine, University of Oklahoma Health Sciences; Center, Oklahoma City.; Atypical mycobacteria, which are common opportunistic pathogens in patients with AIDS, have not been previously implicated in the pathogenesis of paranasal sinus infections; we describe two such patients. Clinical and radiographic evidence of bilateral maxillary and ethmoid sinusitis was observed for one patient; his
Mycobacterium kansasii sinusitis in a patient with AIDS [letter]: Clin Infect Dis. 1994 Oct;19(4):792-3. Unique Identifier : AIDSLINE MED/95101911; Li CX; Szuba MJ; Schuman P; Crane L; Vazquez JA
Paradoxical presentation of intracranial tuberculomas after chemotherapy in a patient with AIDS [letter]: Clin Infect Dis. 1994 Oct;19(4):793-4. Unique Identifier : AIDSLINE MED/95101912; Ramdas K; Minamoto GY
Primary infection with human immunodeficiency virus that presented as Stevens-Johnson syndrome [letter]: Clin Infect Dis. 1994 Oct;19(4):798. Unique Identifier : AIDSLINE MED/95101915; Mortier E; Zahar JR; Gros I; Vignali JP; Simonpoli AM; Pouchot J; Vinceneux P
Septicemia due to non-O:1 Vibrio cholerae in a patient with AIDS [letter]: Clin Infect Dis. 1994 Oct;19(4):813. Unique Identifier : AIDSLINE MED/95101928; Blanche P; Sicard D; Sevali Garcia J; Paul G; Fournier JM
[Non-systematic vaccines. I]: Aten Primaria. 1994 Sep 15;14(4):737-41. Unique Identifier : AIDSLINE MED/95101939; Batalla Martinez C; Bou Barba V; Comin Bertran E; Espuga Garcia M; Ezpeleta Garcia A; Figueras Camos R; Freixedas Casaponsa R; Ruiz Blanes D; Area Basica de Salud Dr. Pujol i Capsada, El Prat de Llobregat,; Barcelona.
[Geriatric AIDS: a distinct epidemiological pattern (letter)]: Aten Primaria. 1994 Sep 15;14(4):753. Unique Identifier : AIDSLINE MED/95101943; Diez Manglano J; Marin Ballve A; Fiteni Mera I; Amiguet Garcia JA
Defective natural killer activity in gastric cancer patients: possible involvement of suppressor factor receptor.: In Vivo. 1994 May-Jun;8(3):279-83. Unique Identifier : AIDSLINE MED/95101963; Yamaguchi Y; Takashima I; Funakoshi M; Kawami H; Toge T; Department of Surgery, Hiroshima University, Japan.; The mechanism of defective natural killer (NK) activity in gastric cancer patients was studied with respect to the soluble immune suppressor factor receptor on NK cells. Phycoerythrin (PE)-conjugated anti-CD8 and -CD16 antibodies were used for the determination of NK phenotype, and fluorescein isothiocyanate (FITC)-co
Synergistic inhibition of AZT-resistant HIV by AZT combined with poly(I):poly(C12U), without synergistic toxicity to bone marrow progenitor cell elements.: In Vivo. 1994 May-Jun;8(3):375-81. Unique Identifier : AIDSLINE MED/95101981; Gillespie D; Hubbell HR; Carter WA; Midgette P; Elsasser W; Mullaney R; Strayer DR; Department of Neoplastic Diseases, Hahnemann University,; Philadelphia, PA 19102.; Mutation of human immunodeficiency virus (HIV) to drug resistance is an obstacle to HIV containment, and may account for the transitory nature of the improvement in CD4 cell counts of patients receiving azidothymidine ( AZT ). The emergence of AZT-resis
Effects of cardiopulmonary bypass on lymphocytes and their subset counts with or without use of autotransfusion devices.: J Cardiothorac Vasc Anesth. 1994 Oct;8(5):532-5. Unique Identifier : AIDSLINE MED/95102006; Perttila J; Salo M; Pirttikangas CO; Jalonen J; Vainio O; Department of Anaesthesiology, University of Turku, Finland.; Lymphocytes and their subset counts were determined in 30 cardiac surgery patients during cardiopulmonary bypass (CPB) with or without use of an autotransfusion device. In the autotransfusion group, centrifuged and washed autologous red blood cells (median 400 mL [range 200-770 mL]) and in the control group correspond
[Intestinal strongyloidiasis and isosporiasis in AIDS]: Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1994 Dec;161(6):564-6. Unique Identifier : AIDSLINE MED/95102051; Risse JH; Adam G; Langen HJ; Biesterfeld S; Hoffmann R; Klinik fur Radiologische Diagnostick, RWTH Aachen.
Pancreatitis during intravenous pentamidine therapy in an AIDS patient with prior exposure to didanosine.: Ann Pharmacother. 1994 Sep;28(9):1025-8. Unique Identifier : AIDSLINE MED/95102172; Foisy MM; Slayter KL; Hewitt RG; Morse GD; Pharmacy Department, Wellesley Hospital, Toronto, Ontario,; Canada.; OBJECTIVE: To report a case of an HIV-positive man who received sequential didanosine and pentamidine treatment and subsequently developed acute clinical pancreatitis. CASE SUMMARY: In June 1992 didanosine 200 mg po bid was initiated in a 30-year-old man with AIDS. After a 22-week course of didanosine, the patient was
Neurologic sequelae associated with foscarnet therapy.: Ann Pharmacother. 1994 Sep;28(9):1035-7. Unique Identifier : AIDSLINE MED/95102175; Lor E; Liu YQ; San Francisco General Hospital, CA 94110.; OBJECTIVE: To report three cases of possible foscarnet-induced neurologic sequelae. CASE SUMMARY: We report two cases of seizures and one case of hand cramping and finger paresthesia after starting foscarnet therapy with no evidence of predisposing risk factors, such as serum laboratory abnormalities, renal dysfunctio
Treatment of fungal infections in patients with HIV-infection or AIDS [editorial]: Int J Med Microbiol Virol Parasitol Infect Dis. 1994 Jun;281(1):1-7. Unique Identifier : AIDSLINE MED/95102221; Meyer RD
[Risk of transmission of HIV by blood products]: Infusionsther Transfusionsmed. 1994 Oct;21(5):295-6. Unique Identifier : AIDSLINE MED/95102291; Gurtler L
Detection of primary HIV infection by a second-generation HIV(p24) antigen test.: Infusionsther Transfusionsmed. 1994 Oct;21(5):333-6. Unique Identifier : AIDSLINE MED/95102298; Thies K; Anders C; Baldus M; Schleiffer T; Weber B; Rabenau H; Hellstern P; Institut fur Transfusionsmedizin und Immunhamatologie, Stadt; Ludwigshafen am Rhein, FRG.; We studied the course of a primary HIV infection in a 54-year-old woman. Probably the source of infection was sexual intercourse, since other risks, such as i.v. drug use, acupuncture and transfusion were excluded. On admission she presented with fever, a maculopapular rash, and moderate enlargement of nuchal lymph no
The role of calcium and N-linked glycans in the oligomerization and carbohydrate binding properties of human immunodeficiency virus external envelope glycoprotein [published erratum appears in Glycoconj J 1994 Oct;11(5):500]: Glycoconj J. 1994 Apr;11(2):73-9. Unique Identifier : AIDSLINE MED/95102311; Haidar M; Seddiki N; Gluckman JC; Gattegno L; Laboratoire de Biologie Cellulaire, Faculte de Medecine; Paris-Nord, Bobigny, France.; Envelope glycoproteins of human immunodeficiency virus (gp120 and gp41) occur as oligomers. Here, we show by gel filtration analysis that gp120 oligomerization in vitro is calcium- and temperature-dependent. Recombinant gp120 (rgp120) species were recovered as monomers at 20 degrees C in the absence of calcium, but as
Patterns of cocaine use and HIV infection among injection drug users in a methadone clinic.: J Subst Abuse. 1994;6(2):169-78. Unique Identifier : AIDSLINE MED/95102318; Nemoto T; Institute for Health Policy Studies, School of Medicine,; University of California, San Francisco 94109.; To investigate patterns of cocaine use, a total of 440 injection drug users (IDUs) in two consecutive cohorts were recruited from a methadone maintenance program in New York City. IDUs who had injected cocaine more frequently during the prior year were more likely to be found HIV positive than IDUs who had injected co
Transmission of tuberculosis by patients with HIV infection [letter; comment] [see comments]: BMJ. 1994 Dec 3;309(6967):1515. Unique Identifier : AIDSLINE MED/95102382; Scott GM; Holton J
Report of Advisory Council on the Misuse of Drugs: AIDS and drug misuse update [editorial]: Addiction. 1994 Oct;89(10):1211-3. Unique Identifier : AIDSLINE MED/95102389; Raistrick D
Drug-related behavior change for HIV transmission among American injection drug users.: Addiction. 1994 Oct;89(10):1309-17. Unique Identifier : AIDSLINE MED/95102400; Celentano DD; Munoz A; Cohn S; Nelson KE; Vlahov D; Department of Health Policy and Management, Johns Hopkins School; of Hygiene and Public Health, Baltimore, MD.; While high risk drug-related behaviors for human immunodeficiency virus (HIV) transmission among injection drug users (IDUs) are asserted to have declined over time in response to the AIDS epidemic, evidence from longitudinal cohorts has been sparse. In a cohort of 810 IDUs (442 seronegatives and 368 seropositives) in
Study of the retinal fiber layer in patients with acquired immunodeficiency syndrome [letter; comment]: Ger J Ophthalmol. 1994 Aug;3(4-5):258-9. Unique Identifier : AIDSLINE MED/95102425; Geier SA; Klauss V; Goebel FD
Typing of Pneumocystis carinii strains that infect humans based on nucleotide sequence variations of internal transcribed spacers of rRNA genes.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):102S. Unique Identifier : AIDSLINE MED/95102577; Lu JJ; Bartlett MS; Shaw MM; Smith JW; Lee CH; Department of Pathology and Laboratory Medicine, Indiana; University School of Medicine, Indianapolis 46202.
Sequence differences in the rRNA ITS regions identify specific isolates of P. carinii.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):107S. Unique Identifier : AIDSLINE MED/95102581; Ortiz-Rivera M; Liu Y; Felder R; Leibowitz MJ; Department of Molecular Genetics and Microbiology, UMDNJ-Robert; Wood Johnson Medical School, Piscataway 08854.
Detection of Pneumocystis DNA in serum and circulating cells is not a good diagnostic marker for Pneumocystosis in HIV patients.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):112S. Unique Identifier : AIDSLINE MED/95102586; Tamburrini E; Mencarini P; De Luca A; Visconti E; Antinori A; Ortona E; Siracusano A; Inf. Dis. Dept., Catholic Univ., Roma, Italy.
ATCC--an international repository for Pneumocystis strains.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):124S. Unique Identifier : AIDSLINE MED/95102598; Nerad TA; American Type Culture Collection, Rockville, MD 20852.
Ultrastructural identification of AIDS associated microsporidiosis.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):24S. Unique Identifier : AIDSLINE MED/95102607; Cali A; Weiss L; Takvorian P; Tanowitz H; Wittner M; Dept. Biological Sciences, Rutgers Univ. Newark, N.J. 07102.
Intestinal microsporidiosis: about clinical characteristics and laboratory diagnosis.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):33S. Unique Identifier : AIDSLINE MED/95102615; Deluol AM; Poirot JL; Heyer F; Roux P; Levy D; Rozenbaum W; Rothschild hosp., Paris-France.
First case of Enterocytozoon bieneusi infection in the Czech Republic: comments on the ultrastructure and teratoid sporogenesis of the parasite.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):35S-36S. Unique Identifier : AIDSLINE MED/95102617; Ditrich O; Lom J; Dykova I; Vavra J; Inst. Parasitol., Ceske Budejovice, Czech Republic.
Diagnostic approaches for Encephalitozoon infections in patients with AIDS.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):59S-60S. Unique Identifier : AIDSLINE MED/95102641; Schwartz DA; Bryan RT; Visvesvara GS; Dept. Pathol., Emory Univ. Sch. Med., Atlanta, GA.; In conclusion, at the current time the most important task of the laboratory for proper clinical management of the patient with microsporidiosis is to perform genus-level diagnosis of the agent, i.e. distinguishing Encephalitozoon sp. infection from other microsporidia
Male genital tract microsporidiosis and AIDS: prostatic abscess due to Encephalitozoon hellem.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):61S. Unique Identifier : AIDSLINE MED/95102642; Schwartz DA; Visvesvara G; Weber R; Bryan RT; Dept. Pathol., Emory Univ., Atlanta, GA.
Cryptosporidium parvum: a decade of effort. An overview of the Cleveland workshop.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):68S. Unique Identifier : AIDSLINE MED/95102648; Sterling CR; Department of Veterinary Science, University of Arizona, Tucson; 85721.
Human microsporidiosis: past and present, an overview of the Cleveland workshop.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):69S. Unique Identifier : AIDSLINE MED/95102649; Cali A; Dept. of Biological Sciences, Rutgers University Newark, N.J.; 07102.
Toxoplasma gondii soluble products induce cytokine secretion by macrophages and potentiate in vitro replication of a monotropic strain of HIV.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):7S. Unique Identifier : AIDSLINE MED/95102650; Bala S; Englund G; Kovacs J; Wahl L; Martin M; Sher A; Gazzinelli RT; Lab of Parasitic Diseases, Natl Inst of Allergy and Infect Dis,; Natl Inst of Health, Bethesda, MD 20892.
Different amplification efficiency and nucleotide sequence variation in various Pneumocystis isolates from humans and rats.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):85S. Unique Identifier : AIDSLINE MED/95102662; De Luca A; Ortona E; Margutti P; Visconti E; Tamburrini E; Siracusano A; Inf. Dis.Dept., Catholic Univ., Roma, Italy.
Does Pneumocystis carinii remain infectious in the bloodstream?: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):86S. Unique Identifier : AIDSLINE MED/95102663; Denis CM; Cailliez JC; Aliouat EM; Delcourt P; LePage G; Hermant N; Lamouret M; Dei-Cas E; F.L.S., Univ. Catholique de Lille, France.
Production and characterization of monoclonal antibodies specific for the major surface glycoprotein of Pneumocystis carinii.: J Eukaryot Microbiol. 1994 Sep-Oct;41(5):99S-100S. Unique Identifier : AIDSLINE MED/95102676; Linke MJ; Smulian AG; Yoshihara P; Walzer PD; Cincinnati VAMC, OH.
Litigation ... hospitals' freedom to send patients to tertiary facilities for specialized care [news]: Hosp Health Netw. 1995 Jan 5;69(1):16. Unique Identifier : AIDSLINE MED/95102718
Infective neuropathies.: Curr Opin Neurol. 1994 Oct;7(5):398-401. Unique Identifier : AIDSLINE MED/95102859; Said G; Service de Neurologie, Centre Hospitalier Universitaire de; Bicetre, Universite Paris-sud, CHU de Bicetre, France.; Infective neuropathies encompass neuropathies that are among the most common in the world. Retroviral infection, which includes infection with the human immunodeficiency virus, has now spread worldwide. This virus is responsible for a number of disabling peripheral neuropathies, either from the immune reaction that fo
Human immunodeficiency virus early intervention physician guidelines, second edition. Advisory Group on HIV Early Intervention, Second Edition, American Medical Association.: Arch Fam Med. 1994 Nov;3(11):988-102. Unique Identifier : AIDSLINE MED/95102882; An estimated 1 million people in the United States are presently infected with the human immunodeficiency virus (HIV). Each of these individuals should be under the care of a physician. Moreover, there is general consensus that early intervention should be managed in the primary care s
Prevalence, incidence, and correlates of syphilis seroreactivity in multiethnic San Francisco neighborhoods.: Ann Epidemiol. 1994 Nov;4(6):460-5. Unique Identifier : AIDSLINE MED/95102902; Siegel D; Larsen SA; Golden E; Morse S; Fullilove MT; Washington AE; Center for AIDS Prevention Studies, University of California, San; Francisco.; To examine the extent of infection with syphilis in an inner-city community, we determined the prevalence, incidence, and correlates of syphilis seroreactivity in a representative sample of unmarried whites, African Americans, and Hispanics living in San Francisco during 1988 to 1989 and again 1 year later in 1989 to
Human immunodeficiency virus type 1 antibody status and changes in risk behavior among drug users.: Ann Epidemiol. 1994 Nov;4(6):466-71. Unique Identifier : AIDSLINE MED/95102903; McCusker J; Bigelow C; Stoddard AM; Zorn M; School of Public Health, University of Massachusetts, Amherst.; The associations of human immunodeficiency virus type 1 (HIV-1) antibody status and recent testing with risk behavior change were examined in a cohort of drug users enrolled in a randomized trial of acquired immunodeficiency syndrome (AIDS) education programs at a short-term inpatient detoxification facility. Four hun
Epidemiologic factors correlated with multiple sexual partners among women receiving prenatal care.: Ann Epidemiol. 1994 Nov;4(6):472-9. Unique Identifier : AIDSLINE MED/95102904; Rosenberg EI; Bayona M; Brown CH; Specter SC; Department of Epidemiology and Biostatistics, University of South; Florida College of Public Health, Tampa 33612-3805.; A cross-sectional survey methodology was used to respond to the need of a local health department to identify correlates of high-risk behaviors related to human immunodeficiency virus (HIV) transmission among pregnant women attending prenatal care clinics. This study of 488 maternity patients was conducted at two publ
Epstein-Barr virus, infectious mononucleosis, and posttransplant lymphoproliferative disorders.: Transplant Sci. 1994 Sep;4(1):61-79. Unique Identifier : AIDSLINE MED/95103132; Nalesnik MA; Starzl TE; Division of Transplantation Pathology, University of Pittsburgh; Medical Center, PA 15213.; PTLD may be considered as an opportunistic cancer in which the immunodeficiency state of the host plays a key role in fostering the environment necessary for abnormal lymphoproliferation. The following discussion reflects our own current thoughts regarding events which may result in PTLD and its sequelae. Many of the
Immunological aspects of the effect of pentoxifylline (Trental) (a brief review).: Acta Microbiol Immunol Hung. 1994;41(2):121-6. Unique Identifier : AIDSLINE MED/95103149; Balazs C; Kiss E; Third Department of Medicine, Kenezy Teaching Hospital,; Debrecen, Hungary.; Pentoxifylline (methixanthine derivate) has haemorheological activity, thought to based on its ability to reduce blood viscosity and increase the filterability of blood cells and widely used for the treatment of various types of vascular insufficiency. Recent studies provide evidence for the effect of this drug on imm
[The opinions of Quebec physicians regarding AIDS: Part II]: Can J Public Health. 1994 Sep-Oct;85(5):344-6. Unique Identifier : AIDSLINE MED/95103420; Boyer R; Fortin C; Duval B; Nadeau D; Godin G; Centre de recherche, Centre Hospitalier de l'Universite Laval.; Based on a representative sample of Quebec physicians (n = 879), this study assesses physicians motivation to perform a clinical examination on an HIV-infected patient and their opinion about issues related to HIV screening. Confronted with an HIV-infected patient, 70% of physicians would perform a clinical examinati
Food supplements for HIV patients.: Can Nurse. 1994 Dec;90(11):15. Unique Identifier : AIDSLINE MED/95103494; Scheuerman D
[Clinico-histopathologic correlations in cytomegalovirus retinitis in the acquired immunodeficiency syndrome]: Cesk Oftalmol. 1994 Oct;50(5):310-5. Unique Identifier : AIDSLINE MED/95103617; Boguszakova J; Sach J; Stankova M; I. ocni klinika VFN a 1. LF UK, Praha.; The authors describe histological changes of the retina and chorioid in cytomegalovirus retinitis in a patient with manifest AIDS who died after a severe opportunic infection. Consistent with data in the literature, they describe in addition to necrotic changes also inflammatory ma
AIDS in the tropics.: Dermatol Clin. 1994 Oct;12(4):747-52. Unique Identifier : AIDSLINE MED/95103819; Abraham A; Department of Dermatology, St. John's Medical College Hospital,; Bangalore, India.; The epidemiology and clinical manifestations of AIDS in the tropics differ considerably from classic descriptions of the disease. Clinical features are reviewed in this article, with emphasis on infectious and nutritional manifestations. Management strategy in the tropics also is outlined.
Health-related quality-of-life assessment in medical care.: Dis Mon. 1995 Jan;41(1):1-71. Unique Identifier : AIDSLINE MED/95104068; McSweeny AJ; Creer TL; Department of Psychiatry Medical College of Ohio, Toledo.; The concept of assessing health-related quality of life has a brief and vibrant history. In this monograph, theoretical issues related to the term and the reasons assessment of quality of life is important are discussed. There is a great deal of ambiguity surrounding definitions of the concept. This equivocation is ca
Malignant otitis externa in AIDS patients: case report and review of the literature.: Ear Nose Throat J. 1994 Oct;73(10):772-4, 777-8. Unique Identifier : AIDSLINE MED/95104121; Weinroth SE; Schessel D; Tuazon CU; Department of Medicine, George Washington University Medical; Center, Washington, DC.; Malignant otitis externa is a necrotizing infection of the external ear canal and surrounding soft tissue and bone, usually caused by Pseudomonas aeruginosa. The infection classically occurs in diabetic patients, however recently, several patients with the acquired immunodeficiency syndrome (AIDS) have been reported t
Reducing inner-city women's AIDS risk activities: a study of single, pregnant women.: Health Psychol. 1994 Sep;13(5):397-403. Unique Identifier : AIDSLINE MED/95104157; Hobfoll SE; Jackson AP; Lavin J; Britton PJ; Shepherd JB; Applied Psychology Center, Kent State University, Ohio 44242.; Behavioral change reduces risk of HIV infection and development of AIDS. We compared 206 inner-city women who were randomly assigned to a 4-session AIDS-prevention group or to one of two controls, a health-promotion group or a no-intervention group. AIDS-prevention and health-promotion groups provided information, beh
An experimental model for study of Candida survival and transmission in human volunteers.: Eur J Clin Microbiol Infect Dis. 1994 Jul;13(7):590-5. Unique Identifier : AIDSLINE MED/95104212; Rangel-Frausto MS; Houston AK; Bale MJ; Fu C; Wenzel RP; Department of Internal Medicine C41 GH, University of Iowa; College of Medicine, Iowa City 52242.; In order to determine the potential for cross-transmission of Candida spp. between health-care workers and patients, the survival of clinical isolates of five species of Candida on the palms of human volunteers was tested. One hundred microliters of a McFarland 1.0 density suspension (5 x 10(5) cfu) from an overnight
Efficacy of acute phase and maintenance therapy with itraconazole in an AIDS patient with sporotrichosis.: Eur J Clin Microbiol Infect Dis. 1994 Jul;13(7):609-12. Unique Identifier : AIDSLINE MED/95104217; Bolao F; Podzamczer D; Ventin M; Gudiol F; Infectious Disease Service, Ciutat Sanitaria de Bellvitge,; University of Barcelona, Spain.; An AIDS patient with sporotrichosis who improved with itraconazole therapy after consecutive failure of ketoconazole, saturated solution of potassium iodide, fluconazole and amphotericin B is presented. In addition, long-term therapy with high doses of itraconazole was well tolerated and effective in avoiding relapse.
Development of resistance to macrolide antibiotics in an AIDS patient treated with clarithromycin for Campylobacter jejuni diarrhea.: Eur J Clin Microbiol Infect Dis. 1994 Jul;13(7):612-5. Unique Identifier : AIDSLINE MED/95104218; Funke G; Baumann R; Penner JL; Altwegg M; Department of Medical Microbiology, University of Zurich,; Switzerland.; In an AIDS patient with diarrhea, identical isolates of Campylobacter jejuni susceptible and, later, resistant to macrolide antibiotics were isolated from feces before and after treatment with clarithromycin. Results of rRNA gene restriction analysis and serotyping suggest that development of resistance rather than si
Low risk of HIV transmission in rape victims [letter]: Eur J Clin Microbiol Infect Dis. 1994 Jul;13(7):622. Unique Identifier : AIDSLINE MED/95104221; Lopez-Varela M; Garcia-Rodriguez J; Martinez-Zapico R
Dysregulation of interleukin-7 receptor may generate loss of cytotoxic T cell response in human immunodeficiency virus type 1 infection.: Eur J Immunol. 1994 Dec;24(12):2927-34. Unique Identifier : AIDSLINE MED/95104273; Carini C; McLane MF; Mayer KH; Essex M; Department of Cancer Biology, Harvard School of Public Health,; Boston, MA 02115.; Virus-specific cytotoxic T lymphocytes (CTL) play a crucial role in modulating an immune response against human immunodeficiency type 1 (HIV-1) infection. The generation of effector cytotoxic cells from CTL precursors involves intricate interactions with antigen via T cell receptors (TcR) and soluble cytokines. Interl
Co-stimulation by anti-immunoglobulin is required for B cell activation by CD40Llow T cells.: Eur J Immunol. 1994 Dec;24(12):2993-9. Unique Identifier : AIDSLINE MED/95104282; Poudrier J; Owens T; Department of Medicine, McGill University, Montreal, Canada.; During cognate B:T interactions, B cells encounter antigen (Ag) through surface immuno-globulin (sIg) and present antigenic peptides to T helper (Th) cells. However, most in vitro systems used to study contact events involved in the delivery of T help for B cells circumvent the requirement for T cell Ag specificity by
T cell receptor gamma delta repertoire in HIV-1-infected individuals.: Eur J Immunol. 1994 Dec;24(12):3044-9. Unique Identifier : AIDSLINE GENBANK/S75862; Hinz T; Wesch D; Friese K; Reckziegel A; Arden B; Kabelitz D; Department of Immunology, Paul Ehrlich Institute, Langen,; Germany.; While V gamma 9/V delta 2 cells dominate among peripheral blood gamma delta T cells in healthy adults, the majority of gamma delta T cells in most HIV-1-infected individuals express V delta 1. We asked whether these elevated levels of V delta 1 T cells were due to clonal expansion. Three-color flow cytometry with mono
Increased susceptibility of mice infected with Schistosoma mansoni to recombinant vaccinia virus: association of viral persistence with egg granuloma formation.: Eur J Immunol. 1994 Dec;24(12):3050-6. Unique Identifier : AIDSLINE MED/95104291; Actor JK; Marshall MA; Eltoum IA; Buller RM; Berzofsky JA; Sher A; Laboratory of Parasitic Disease, NIAID, National Institutes of; Health, Bethesda, MD 20892.; BALB/c mice infected 7 weeks previously with Schistosoma mansoni and challenged with a recombinant vaccinia virus vPE16 expressing the human immunodeficiency virus envelope protein gp160 show a marked delay in hepatic viral clearance as compared to mice infected with vPE16 alone. This increase in viral persistence is
CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity.: Eur J Immunol. 1994 Dec;24(12):3068-72. Unique Identifier : AIDSLINE MED/95104294; Kagi D; Ledermann B; Burki K; Hengartner H; Zinkernagel RM; Institute of Experimental Immunology, Department of Pathology,; University of Zurich, Switzerland.; Growth of Listeria monocytogenes is mainly controlled by macrophages, which are activated by specific T cells. A potential role of CD8+ T cells by direct lysis of infected cells was investigated in perforin-deficient mice generated by homologous recombination. The absence of perforin-mediated cytotoxicity resulted in
Peyer's patch CD8+ memory T cells secrete T helper type 1 and type 2 cytokines and provide help for immunoglobulin secretion.: Eur J Immunol. 1994 Dec;24(12):3087-92. Unique Identifier : AIDSLINE MED/95104297; Lagoo AS; Eldridge JH; Lagoo-Deenadaylan S; Black CA; Ridwan BU; Hardy KJ; McGhee JR; Beagley KW; Department of Medicine (Division of Rheumatology and Clinical; Immunology), University of Mississippi Medical Center, Jackson.; Analysis of cytokine gene expression by reverse transcription-polymerase chain reaction (RT-PCR) demonstrated high spontaneous levels of transcripts for multiple cytokines in murine Peyer s patches (PP) compared to spleen and peripheral lymph nodes. This is consistent with the presence of active germinal centers in PP
T lymphocyte-mediated antiviral immune responses in mice are diminished by treatment with monoclonal antibody directed against the interleukin-2 receptor.: Eur J Immunol. 1994 Dec;24(12):3093-9. Unique Identifier : AIDSLINE MED/95104298; Utermohlen O; Tarnok A; Bonig L; Lehmann-Grube F; Heinrich-Pette-Institut fur Experimentelle Virologie und; Immunologie an der Universitat Hamburg, Germany.; Blocking the interleukin-2 receptor s alpha-chain in lymphocytic choriomeningitis virus-infected mice by treatment with monoclonal antibodies diminished the increase of numbers of CD8+ T lymphocytes in spleens and prevented CD8+ T lymphocyte-mediated virus clearance from organs as well as generation of virus-specific
Low-level infection with Trichuris muris significantly affects the polarization of the CD4 response.: Eur J Immunol. 1994 Dec;24(12):3113-8. Unique Identifier : AIDSLINE MED/95104301; Bancroft AJ; Else KJ; Grencis RK; School of Biological Sciences, University of Manchester, GB.; Resistance and susceptibility to the intestinal nematode Trichuris muris has been shown to be dependent upon the induction of T helper type 2 (Th2) or Th1 cells, respectively. This study demonstrates that in a normally resistant strain of mouse, i.e. BALB/K which mounts a dominant Th2 response, sub-threshold levels of
[An index of HIV infection risk in the population]: Epidemiol Prev. 1994 Sep;18:151-6. Unique Identifier : AIDSLINE MED/95104397; Campostrini S; Dipartimento di Scienze Statistiche, Universita di Padova.; The paper presents a risk index constructed on the basis of some sexual behaviour-related variables. It is intended for measuring the risk of exposure to HIV infection for the general population. Variables are from a study on Lifestyle and Health conducted on a sample of the population living in the London, Edinburgh,
Mathematical modelling of chemotherapy in HIV infection.: Folia Biol (Praha). 1994;40(3):103-11. Unique Identifier : AIDSLINE MED/95104514; Hraba T; Dolezal J; Institute of Molecular Genetics, Academy of Sciences of the Czech; Republic, Praha.; A mathematical model of CD4+ lymphocyte depletion in HIV infection is used to simulate and analyse the effect of AZT treatment. In most cases, permanent administration of AZT is observed to stop the CD4+ lymphocyte count decline and to stimulate their
Cell-mediated immunity in invasive cervical carcinoma associated with human papillomavirus types 16 and 18 infection [letter]: Int J Gynaecol Obstet. 1994 Jul;46(1):67-8. Unique Identifier : AIDSLINE MED/95104580; Park TK; Kim SN; Lee CH
Interferon alfa treatment of chronic hepatitis B: randomized trial in a predominantly homosexual male population.: Gastroenterology. 1995 Jan;108(1):165-71. Unique Identifier : AIDSLINE MED/95104631; Wong DK; Yim C; Naylor CD; Chen E; Sherman M; Vas S; Wanless IR; Read S; Li H; Heathcote EJ; Department of Medicine, University of Toronto, Ontario, Canada.; BACKGROUND/AIMS: It has been suggested that human immunodeficiency virus (HIV) coinfection and male homosexuality predict poor response to interferon alfa therapy of chronic hepatitis B. The aim of this study was to examine the effect of HIV coinfection on the response of chronic hepatitis B virus (HBV) infection to i
Human immunodeficiency virus 1-associated necrotizing cholangitis caused by infection with Septata intestinalis.: Gastroenterology. 1995 Jan;108(1):247-51. Unique Identifier : AIDSLINE MED/95104642; Willson R; Harrington R; Stewart B; Fritsche T; Department of Medicine, University of Washington, Seattle.; A 30-year-old man with acquired immunodeficiency syndrome developed human immunodeficiency virus 1-related cholangiopathy with atypical radiographic features showing extensive hepatobiliary involvement. Extended clinical evaluation, including endoscopic retrograde cholangiopancreatography, and the results of both ultr
[AIDS: combination drug partner for AZT. HIV infection--new nucleoside analog]: Fortschr Med. 1994 Oct 30;112(30):50. Unique Identifier : AIDSLINE MED/95104724; Bottger S
[Intestine-associated immune system stimulation. Saccharomyces boulardii--mechanism of action]: Fortschr Med. 1994 Oct 30;112(30):52-3. Unique Identifier : AIDSLINE MED/95104725; Arnheim K
Appetite stimulants in terminal care: treatment of anorexia.: Hosp J. 1993;9(2-3):73-83. Unique Identifier : AIDSLINE MED/95104792; Grauer PA; Anorexia is a common problem in terminally ill patients. The loss of appetite brings with it physical, psychological, and social problems. Effective treatment, therefore, should be multidimensional. The pharmacist is well-positioned to evaluate the appropriate use of medications for their effects on appetite, weight g
Co-selection in immune network theory and in AIDS pathogenesis.: Immunol Cell Biol. 1994 Aug;72(4):338-46. Unique Identifier : AIDSLINE MED/95104898; Hoffmann GW; Department of Microbiology and Immunology, University of British; Columbia, Vancouver, Canada.; Co-selection is a term used to denote the mutual positive selection of individual members from within two diverse populations, such that selection of members within one population is dependent on interaction with (recognition of) one or more member(s) within the other population. Co-selection is a recurring theme of t
Immunomodulatory spectrum of lipids associated with Mycobacterium avium serovar 8.: Infect Immun. 1995 Jan;63(1):126-33. Unique Identifier : AIDSLINE MED/95104985; Barrow WW; Davis TL; Wright EL; Labrousse V; Bachelet M; Rastogi N; Unite de la Tuberculose et des Mycobacteries, Institut Pasteur,; Pointe-a-Pitre, Guadeloupe, French West Indies.; Lipid fractions obtained from Mycobacterium avium serovar 8 were assessed for the ability to affect various immune functions of human peripheral blood mononuclear cells (PBM). Lipids included a total lipid fraction and fractions eluted from silicic acid column separation of that total lipid fraction, using chloroform
Monophosphoryl lipid A behaves as a T-cell-independent type 1 carrier for hapten-specific antibody responses in mice.: Infect Immun. 1995 Jan;63(1):168-74. Unique Identifier : AIDSLINE MED/95104991; Myers KR; Beining P; Betts M; Snippe H; Inman J; Golding B; Ribi ImmunoChem Research, Inc., Hamilton, Montana 59840.; It is known that the lipopolysaccharide (LPS) of gram-negative bacteria, in addition to being a potent adjuvant, is an effective carrier for covalently associated haptens. However, the toxic nature of most forms of LPS precludes their use as adjuvants or carriers for human vaccines. 4 -Monophosphoryl lipid A (MLA), a
Fibronectin-binding antigen 85 and the 10-kilodalton GroES-related heat shock protein are the predominant TH-1 response inducers in leprosy contacts.: Infect Immun. 1995 Jan;63(1):88-93. Unique Identifier : AIDSLINE MED/95105031; Launois P; N'Diaye MN; Cartel JL; Mane I; Drowart A; Van Vooren JP; Sarthou JL; Huygen K; Immunology Unit, Institut Pasteur de Dakar, Senegal.; Peripheral blood mononuclear cells from 27 healthy leprosy contacts were analyzed for lymphoproliferation and TH-1 cytokine secretion (interleukin-2 and gamma interferon) in response to heat shock proteins with molecular masses of 65, 18, and 10 kDa from Mycobacterium leprae and the 30-32-kDa antigen 85 (Ag 85) from M
Analysis of immunization route-related variation in the immune response to heat-killed Salmonella typhimurium in mice.: Infect Immun. 1995 Jan;63(1):99-103. Unique Identifier : AIDSLINE MED/95105034; Thatte J; Rath S; Bal V; National Institute of Immunology, New Delhi, India.; In examinations of the factors regulating the quality and quantity of the immune response to Salmonella typhimurium, we have shown previously that live and heat-killed preparations of S. typhimurium can induce gamma interferon-dominant and interleukin-4-dominant immune responses, respectively, upon intraperitoneal (i.
T-cell adjuvants.: Int J Immunopharmacol. 1994 Sep;16(9):703-10. Unique Identifier : AIDSLINE MED/95105072; Hadden JW; Department of Internal Medicine, University of South Florida; Medical College, Tampa 33612.; T-cell adjuvancy involves the use of agents to stimulate preferentially delayed type hypersensitivity (DTH). Traditional adjuvants like Alum, Freunds, muramyl peptides, and endotoxins are not selective. Natural infection (e.g. vaccinia) may yield selective DTH. Low dose cyclophosphamide (CY) with mycobacteria was the
Structure of a novel phosphocholine-containing glycoglycerolipid from Mycoplasma fermentans.: J Biol Chem. 1994 Dec 30;269(52):33123-8. Unique Identifier : AIDSLINE MED/95105203; Matsuda K; Kasama T; Ishizuka I; Handa S; Yamamoto N; Taki T; Department of Microbiology, Faculty of Medicine, Tokyo Medical; and Dental University, Japan.; Mycoplasma fermentans is thought to be a pathogen of rheumatoid arthritis or cofactor of AIDS. A novel phosphocholine-containing glycoglycerophospholipid named GGPL-I was isolated from a M. fermentans-infected human helper T-cell culture. It was revealed that GGPL-I is a lipid component of the M. fermentans and a majo
Histopathological changes in lymph nodes of cats experimentally infected with the feline immunodeficiency virus (FIV).: J Comp Pathol. 1994 Aug;111(2):165-74. Unique Identifier : AIDSLINE MED/95105380; Parodi AL; Femenia F; Moraillon A; Crespeau F; Fontaine JJ; Laboratory of Pathology, URA-INRA of Molecular Genetics, Maisons; Alfort, France.; Twelve specific-pathogen-free (SPF) kittens aged 8-12 weeks were serially infected in pairs every 6 weeks, by the intraperitoneal route, with the feline immunodeficiency virus (FIV). Three additional SPF kittens were kept as controls. The infected animals were killed 10 weeks after inoculation, during the primary phas
The changing epidemiology of human immunodeficiency virus infection in older persons.: J Am Geriatr Soc. 1995 Jan;43(1):7-9. Unique Identifier : AIDSLINE MED/95105422; Gordon SM; Thompson S; Emory University School of Medicine, Department of Medicine,; Atlanta, Georgia.; OBJECTIVE: To describe the epidemiology of human immunodeficiency virus (HIV) infection diagnosed in persons aged 60 years and older at a large urban county hospital. DESIGN: Retrospective chart review of patients, aged 60 years and older, diagnosed with HIV infection, among 6,493 patients identified with positive EIA
Tropical pyomyositis.: J Infect. 1994 Sep;29(2):121-7. Unique Identifier : AIDSLINE MED/95105557; Sissolak D; Weir WR; Swiss Tropical Institute, Medical Department, Basle.
p24 antigenaemia in HIV-1 infected Brazilians correlates with other markers of disease progression.: J Infect. 1994 Sep;29(2):129-31. Unique Identifier : AIDSLINE MED/95105558; Hofer CB; Pinto ME; Zajdenverg R; Schechter M; Programa SIDA/AIDS, Hospital Universitario Clementino Fraga; Filho, Universidade Federal do Rio de Janeiro, Brazil.
A case of disseminated toxoplasmosis-value of PCR for the diagnosis.: J Infect. 1994 Sep;29(2):133-8. Unique Identifier : AIDSLINE MED/95105559; Liesenfeld O; Roth A; Weinke T; Foss HD; Hahn H; Institut fur Medizinische Mikrobiologie und; Infektionsimmunologie, Freien Universitat Berlin, Germany.; Extracerebral toxoplasmosis has recently gained greater attention as a consequence of the AIDS epidemic. Serological techniques are unreliable, while isolation of the parasite is either time-consuming or insensitive. We here report a case of disseminated toxoplasmosis in a patient with AIDS. Diagnosis was suggested by
An analysis of 900 consecutive admissions to a regional infection unit.: J Infect. 1994 Sep;29(2):189-93. Unique Identifier : AIDSLINE MED/95105566; Dykhuizen RS; Trent RJ; Pacitti DP; Reid TM; Douglas JG; Smith CC; Infection Unit, City Hospital, Aberdeen, Scotland, U.K.; A total of 900 consecutive admissions to the Regional Infection Unit at the City Hospital Aberdeen in 1991 have been analysed and the results compared with a similar study during 1980 and 1981. The annual number of admissions increased from 605 to 900, of which 72% in 1991 had proven infections compared with 60% a dec
Effect of heat on viral protein production and budding in cultured mammalian cells.: Int J Hyperthermia. 1994 Sep-Oct;10(5):627-41. Unique Identifier : AIDSLINE MED/95105608; Herman PP; Yatvin MB; Department of Radiation Oncology, Oregon Health Sciences; University, Portland 97201.; The life cycle of enveloped viruses is intimately associated with, and influenced by, host cell membrane organization, which is altered by hyperthermia. Hyperthermia-modified Moloney murine leukaemia virus (M-MuLV) release, protein production and intracellular protein processing in a chronically infected cultured muri
Acute miliary blastomycosis in an AIDS patient.: J Ky Med Assoc. 1994 Nov;92(11):450-2. Unique Identifier : AIDSLINE MED/95105642; Srinath L; Ahkee S; Huang A; Raff MJ; Ramirez JA; Department of Medicine School of Medicine, University of; Louisville, Kentucky.; The incidence of blastomycosis in immunocompromised patients with HIV infection is very low when compared to other mycoses. Of the 19 cases of blastomycosis described in HIV-infected patients, only four had a miliary pattern on chest x-ray. A case of acute miliary blastomycosis in an HIV infected patient from Louisvil
Mass spectrometric identification of a naturally processed melanoma peptide recognized by CD8+ cytotoxic T lymphocytes.: J Exp Med. 1995 Jan 1;181(1):363-8. Unique Identifier : AIDSLINE MED/95105714; Castelli C; Storkus WJ; Maeurer MJ; Martin DM; Huang EC; Pramanik BN; Nagabhushan TL; Parmiani G; Lotze MT; Istituto Nazionale Tumori, Milan, Italy.; We and others have previously reported that melanoma-specific, cytotoxic T lymphocytes (CTL) define a minimum of six class I-presented peptide epitopes common to most HLA-A2+ melanomas. Here we show that three of these peptide epitopes are coordinately recognized by a CTL clone obtained by limiting dilution from the p
Interleukin 12 is effective treatment for an established systemic intracellular infection: experimental visceral leishmaniasis.: J Exp Med. 1995 Jan 1;181(1):387-91. Unique Identifier : AIDSLINE MED/95105718; Murray HW; Hariprashad J; Division of Infectious Diseases, Cornell University Medical; College, New York 10021.; When administered at or near the initiation of experimental intracellular infection caused by Leishmania major, Toxoplasma gondii, or Cryptococcus neoformans, treatment with the immuno-regulatory cytokine interleukin 12 (IL-12), induces protective antimicrobial activity. In contrast, once infections are established, I
Impaired mucosal immune responses in interleukin 4-targeted mice.: J Exp Med. 1995 Jan 1;181(1):41-53. Unique Identifier : AIDSLINE MED/95105722; Vajdy M; Kosco-Vilbois MH; Kopf M; Kohler G; Lycke N; Department of Medical Microbiology and Immunology, University of; Goteborg, Sweden.; Interleukin 4-targeted (IL-4-/-) mice are defective in T helper (Th)2 cytokine production as determined after nematode infection. As Th2 cells appear to be selectively induced by oral immunization we investigated the ability of IL-4-/- mice to respond to perorally administered antigen. We found that IL-4-/- mice faile
CD8+ T lymphocytes provide helper activity for IgE synthesis in human immunodeficiency virus-infected patients with hyper-IgE [see comments]: J Exp Med. 1995 Jan 1;181(1):423-8. Unique Identifier : AIDSLINE MED/95105725; Paganelli R; Scala E; Ansotegui IJ; Ausiello CM; Halapi E; Fanales-Belasio E; D'Offizi G; Mezzaroma I; Pandolfi F; Fiorilli M; et al; Department of Clinical Medicine, University of Rome, La Sapienza,; Italy.; Increased levels of serum IgE and eosinophilia have been described in human immunodeficiency virus (HIV) infection, almost exclusively in patients with CD4+ cell count
The functional role of CD8+ T helper type 2 cells [comment]: J Exp Med. 1995 Jan 1;181(1):5-7. Unique Identifier : AIDSLINE MED/95105728; Seder RA; Le Gros GG; Laboratory of Clinical Investigation, National Institute of; Allergy and Infectious Diseases, National Institutes of Health,; Bethesda, Maryland 20892-1892.
Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment.: J Exp Med. 1995 Jan 1;181(1):79-91. Unique Identifier : AIDSLINE +; Lehner PJ; Wang EC; Moss PA; Williams S; Platt K; Friedman SM; Bell JI; Borysiewicz LK; Department of Medicine, University of Wales College of Medicine,; Heath Park, Cardiff.; The major histocompatibility complex class I-restricted cytotoxic T lymphocyte (CTL) response is important in the clearance of viral infections in humans. After influenza A infection, a peptide from the matrix protein, M58-66, is presented in the context of the MHC allele HLA-A0201 and the resulting CTL response is de
High cerebrospinal fluid and serum levels of tumor necrosis factor-alpha in asymptomatic HIV-1 seropositive individuals. Correlation with interleukin-2 and soluble IL-2 receptor.: J Neurol Sci. 1994 Sep;125(2):175-9. Unique Identifier : AIDSLINE MED/95105883; Ciardi M; Sharief MK; Thompson EJ; Salotti A; Vullo V; Sorice F; Cirelli A; Institute of Infectious Diseases, University of Rome, La; Sapienza, Italy.; The relationship between tumour necrosis factor-alpha (TNF-alpha) and the interleukin-2 (ILL-2) system in HIV-1 infection is important in understanding the dynamics of early immune response before the development of acquired immunodeficiency syndrome. Levels of TNF-alpha,
Expression of cytochrome c oxidase subunits encoded by mitochondrial or nuclear DNA in the muscle of patients with zidovudine myopathy.: J Neurol Sci. 1994 Sep;125(2):190-3. Unique Identifier : AIDSLINE MED/95105886; Chariot P; Bonne G; Authier FJ; Marsac C; Gherardi R; Departments of Pathology, Neuropathology, Hopital Henri Mondor,; Creteil, France.; The present study was carried out to determine whether a selective decrease of mitochondrial (mt) DNA-encoded cytochrome c oxidase (CCO) subunits occurs in zidovudine myopathy, as expected with a compound known to induce selective mtDNA depletion. Fourteen HIV-infected patients with zidovudine myopathy were studied. T
Detection of Eber-1 RNA in primary brain lymphomas in immunocompetent and immunocompromised patients.: J Neurooncol. 1994;20(1):47-53. Unique Identifier : AIDSLINE MED/95105903; Bashir R; McManus B; Cunningham C; Weisenburger D; Hochberg F; University of Nebraska Medical Center, Department of Internal; Medicine, Omaha.; Tissue from primary central nervous system lymphoma (PCNSL) which developed in five patients with acquired immuno deficiency syndrome (AIDS), nine patients without immunodeficiency, and two Epstein-Barr virus (EBV)-positive control cell lines (B95-8 and Raji) were examined for the presence of EBER-1 RNA. The tissues w
Diagnosis and prediction of pediatric HIV-1 infection and AIDS: current status.: J Clin Lab Anal. 1994;8(5):309-14. Unique Identifier : AIDSLINE MED/95106017; Ugen KE; Von Feldt JM; Weiner DB; Ziegner UH; Department of Pathology and Laboratory Medicine, University of; Pennsylvania, Philadelphia.; The increase in the incidence of HIV-1 infection in women of child bearing age has resulted in a surge in the number of cases of pediatric AIDS. The World Health Organization (WHO) has estimated that the number of cases of pediatric AIDS worldwide will be at least 10 million by the yea
Use of microplates and fluororeader for ultrasensitive enzyme immunoassay (immune complex transfer enzyme immunoassay) of anti-HTLV-I IgG.: J Clin Lab Anal. 1994;8(5):327-31. Unique Identifier : AIDSLINE MED/95106020; Ishikawa S; Hashida S; Kohno T; Ishikawa E; Department of Biochemistry, Medical College of Miyazaki, Japan.; Previously, an ultrasensitive solid phase enzyme immunoassay (immune complex transfer enzyme immunoassay) was described to detect low levels of anti-HTLV-I IgG in serum below those detectable by conventional methods. In this method, polystyrene balls as solid phase were transferred from test tube to test tube with twe
Maternal HIV infection: parenting and early child development.: J Pediatr Psychol. 1994 Oct;19(5):595-615. Unique Identifier : AIDSLINE MED/95106026; Black MM; Nair P; Harrington D; Division of General Pediatrics, University of Maryland School of; Medicine, Baltimore 21201.; Examined whether support could offset the potential stress of maternal HIV infection with regard to parenting and early child development in two studies of low income, urban, drug-using mothers of infants and toddlers. In one study, support was provided through home intervention; in the other, support was measured thr
Effects of pediatric HIV infection and prenatal drug exposure on mental and psychomotor development.: J Pediatr Psychol. 1994 Oct;19(5):617-27. Unique Identifier : AIDSLINE MED/95106027; Mellins CA; Levenson RL Jr; Zawadzki R; Kairam R; Weston M; Columbia University, New York, New York.; Examined the effects of HIV infection and prenatal drug exposure on infant neurodevelopmental functioning. Three groups of infants were compared: HIV-infected infants, seroreverters, and a comparison group who were prenatally exposed to drugs, but not HIV. Two thirds of the HIV-infected and seroreverter infants were p
Subcutaneous infusion ports in the pediatric patient with hemophilia.: J Pediatr Surg. 1994 Sep;29(9):1220-3. Unique Identifier : AIDSLINE MED/95106086; Girvan DP; deVeber LL; Inwood MJ; Clegg EA; Children's Hospital of Western Ontario, Canada.; Central venous access devices have become important tools in the management of pediatric patients with malnutrition, malignancy, and infections requiring long-term antibiotic treatment. Hemophilia presents a lifetime challenge for venous access and at times can be an urgent or life-threatening situation. Since 1986, t
Effect of cytokines and anti-adhesion molecule antibodies on the adhesion of lymphocytic cells to human syncytiotrophoblast.: J Reprod Immunol. 1994 Aug;27(1):49-62. Unique Identifier : AIDSLINE MED/95106210; Douglas GC; Hu J; Thirkill TL; Hovanes K; Sharma S; King BF; Department of Cell Biology and Human Anatomy, School of Medicine,; University of California, Davis 95616-8643.; We have previously shown that lymphocytic cells bind to cultured syncytiotrophoblast and that this may be important in the lymphocyte-mediated infection of trophoblast with the human immunodeficiency virus (HIV). Leukocyte-trophoblast adhesion may also have implications for normal trophoblast function. The following e
HIV infection: what difference have we made on the course of the disease and where do we go from here? [editorial]: J Natl Med Assoc. 1994 Oct;86(10):737-9. Unique Identifier : AIDSLINE MED/95106309; Idemyor V
What is the significance of black-white differences in risky sexual behavior?: J Natl Med Assoc. 1994 Oct;86(10):745-59. Unique Identifier : AIDSLINE MED/95106311; Johnson EH; Jackson LA; Hinkle Y; Gilbert D; Hoopwood T; Lollis CM; Willis C; Gant L; Department of Family Medicine, Morehouse School of Medicine,; Atlanta, Georgia 30331-2099.; A sample of African-American and white young adults were classified as having multiple sex partners or one sexual partner. Subjects with multiple sexual partners were more likely to use drugs and practice risky sexual behaviors such as having anal intercourse, having sexual experiences with a prostitute, and having a
Global epidemiology of tuberculosis. Morbidity and mortality of a worldwide epidemic [see comments]: JAMA. 1995 Jan 18;273(3):220-6. Unique Identifier : AIDSLINE MED/95106425; Raviglione MC; Snider DE Jr; Kochi A; Tuberculosis Programme, World Health Organization, Geneva,; Switzerland.; This article describes the global epidemiology of tuberculosis and reviews recent estimates of tuberculosis incidence and mortality in the world. The highest prevalence of tuberculosis infection and estimated annual risk of tuberculosis infection are in sub-Saharan Africa and Southeast Asia. Overall, almost 3.8 millio
Cost and outcome of intensive care for patients with AIDS, Pneumocystis carinii pneumonia, and severe respiratory failure.: JAMA. 1995 Jan 18;273(3):230-5. Unique Identifier : AIDSLINE MED/95106427; Wachter RM; Luce JM; Safrin S; Berrios DC; Charlebois E; Scitovsky AA; Medical Service, San Francisco General Hospital Medical Center.; OBJECTIVE--To determine the costs and outcomes associated with intensive care unit (ICU) admission for patients with acquired immunodeficiency syndrome (AIDS)-related Pneumocystis carinii pneumonia (PCP), and severe respiratory failure. DESIGN--Survival and cost-effectiveness analysis. SETTING--A large municipal teach
[A case of HTLV-1 carrier associated with pulmonary cryptococcosis and thymoma]: Nippon Kyobu Shikkan Gakkai Zasshi. 1994 Aug;32(8):778-84. Unique Identifier : AIDSLINE MED/95106524; Inoue Y; Fujii T; Ohtsubo T; Mori N; Ishino T; Hisano H; Kaku M; Koga H; Kohno S; Hara K; et al; Department of Internal Medicine, Hokusho Central Hospital.; A 46-year-old female was admitted to our hospital on December 1991 for further examination of an abnormal shadow on chest X-ray. A huge mass in the upper mediastinum and a thin-walled cavitary lesion in the right upper lobe were found by chest radiography and computed tomography. On March 2, 1992, surgical resection w
[Human gene therapy]: Kango. 1994 Apr;46(4):139-54. Unique Identifier : AIDSLINE MED/95106599; Moriyama Y
[Nursing worldwide]: Kango. 1994 May;46(5):110-1. Unique Identifier : AIDSLINE MED/95106613
[Information from WHO/PHC Nursing Collaborative Center, Tokyo]: Kango. 1994 May;46(5):146-50. Unique Identifier : AIDSLINE MED/95106618
[Human gene therapy--prospects of gene as a drug]: Kango. 1994 May;46(5):153-65. Unique Identifier : AIDSLINE MED/95106619; Moriyama Y
[Care of AIDS patients in the U.S.]: Kango. 1994 Jun;46(6):195-202. Unique Identifier : AIDSLINE MED/95106643; Takano S
Ways of coping among HIV-infected individuals.: J Soc Psychol. 1994 Oct;134(5):655-63. Unique Identifier : AIDSLINE MED/95106756; DeGenova MK; Patton DM; Jurich JA; MacDermid SM; Department of Human Environmental Studies, Central Michigan; University, Mt. Pleasant 48859.; A sample of 85 HIV-infected Americans completed a questionnaire that assessed coping styles, depression, and physical illness. We examined the relationships of emotion-focused coping and problem-focused coping to depression and physical illness. A two-way analysis of variance revealed a significant main effect for emo
Incidence and clinic-pathologic features of non-Hodgkin lymphoma in a cohort of human immunodeficiency virus positive coagulopathic patients [letter]: Leukemia. 1994 Dec;8(12):2246. Unique Identifier : AIDSLINE MED/95106822; Dragoni F; Pacchiarotti A; Mazzucconi MG; Chistolini A; Pescarmona E; De Sanctis V; Peraino M; Uccini S; Gastaldi R; Mandelli F
All-trans retinoic acid for the treatment of AIDS-related Kaposi's sarcoma: results of a pilot phase II study.: Leukemia. 1994;8 Suppl 3:S26-32. Unique Identifier : AIDSLINE MED/95106828; Gill PS; Espina BM; Moudgil T; Kidane S; Esplin JA; Tulpule A; Levine AM; Department of Internal Medicine, University of Southern; California, Los Angeles.; Retinoids have anti-tumor activity in several malignant and premalignant conditions. Since Kaposi s sarcoma is regulated by steroid hormones both in vivo and in vitro, we hypothesized that retinoids may have anti-tumor effects in AIDS-related Kaposi s sarcoma. Thus, 27 patients with mucocutaneous, non-visceral AIDS-re
[Fungemia caused by Candida krusei in a female patient with AIDS (letter)]: Med Clin (Barc). 1994 Nov 19;103(17):678. Unique Identifier : AIDSLINE MED/95106884; Laguna F; Martinez-Suarez JV; Adrados M
[The effect of the type of factor VIII concentrate on the CD4 lymphocyte count in hemophiliacs with human immunodeficiency virus infection: the results of a meta-analysis]: Med Clin (Barc). 1994 Nov 26;103(18):690-4. Unique Identifier : AIDSLINE MED/95106887; Montoro Ronsano JB; Oliveras Martin J; Tusell Puigbert JM; Unidad de Hemofilia, Hospital General Universitari Vall d'Hebron,; Barcelona.; BACKGROUND: The administration of factor VIII concentrates of intermediate purity in HIV+ hemophiliac patients has been related with disorders of the immunologic system of these patients which may be observed in a more acute decrease in CD4 lymphocyte count in relation to that described in patients treated with produc
[The early detection by magnetic resonance of bone infiltration in HIV-related lymphomas (letter)]: Med Clin (Barc). 1994 Nov 26;103(18):715. Unique Identifier : AIDSLINE MED/95106892; Llibre JM; Rothemund N; Poch O; Garcia E
[Prognosis of HIV infection and AIDS. What happened since the 1980's?]: Lakartidningen. 1994 Nov 9;91(45):4093-6. Unique Identifier : AIDSLINE MED/95106918; Giesecke J; Pehrson P; Infektionskliniken, Huddinge sjukhus.
Assessing disease prevalence from inaccurate test results: teaching an old dog new tricks [see comments]: Med Decis Making. 1994 Oct-Dec;14(4):369-73. Unique Identifier : AIDSLINE MED/95107024; Taragin MI; Wildman D; Trout R; Department of Medicine, University of Medicine and Dentistry of; New Jersey, Robert Wood Johnson Medical School, New Brunswick; 08903-0019.; Estimates of disease prevalence are needed for the interpretation of test results as well as for public health decisions. Assessing prevalence may be difficult if a definitive test is unavailable, impractical, or expensive. A formula derived from Bayes theorem can calculate the prevalence of disease in a population b
[Current therapeutic strategies in AIDS-associated Kaposi sarcoma. An overview including results of a personal study]: Med Klin. 1994 Oct 15;89(10):550-5. Unique Identifier : AIDSLINE MED/95107181; Mauss S; Szelenyi H; Jablonowski H; Klinik fur Gastroenterologie und Infektiologie,; Heinrich-Heine-Universitat Dusseldorf.
Quantitation of mitochondrial DNA in human lymphoblasts by a competitive polymerase chain reaction method: application to the study of inhibitors of mitochondrial DNA content.: Mol Pharmacol. 1994 Dec;46(6):1063-9. Unique Identifier : AIDSLINE MED/95107274; Zhang H; Cooney DA; Sreenath A; Zhan Q; Agbaria R; Stowe EE; Fornace AJ Jr; Johns DG; Laboratory of Medicinal Chemistry, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.; With increasing awareness of the mitochondrial toxicity associated with certain 2 ,3 -dideoxynucleosides used in anti-human immunodeficiency virus therapy, procedures for quantitative analyses of drug effects on mitochondrial DNA (mtDNA) have assumed enhanced importance. For this reason we have developed a method to m
Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection [see comments]: N Engl J Med. 1995 Jan 26;332(4):201-8. Unique Identifier : AIDSLINE MED/95107358; Cao Y; Qin L; Zhang L; Safrit J; Ho DD; Aaron Diamond AIDS Research Center, New York University School of; Medicine, NY 10016.; BACKGROUND. In most subjects infected with human immunodeficiency virus type 1 (HIV-1), clinical or laboratory evidence of immunodeficiency develops within 10 years of seroconversion, but a few infected people remain healthy and immunologically normal for more than a decade. Studies of these subjects, termed long-term
Studies in subjects with long-term nonprogressive human immunodeficiency virus infection [see comments]: N Engl J Med. 1995 Jan 26;332(4):209-16. Unique Identifier : AIDSLINE MED/95107359; Pantaleo G; Menzo S; Vaccarezza M; Graziosi C; Cohen OJ; Demarest JF; Montefiori D; Orenstein JM; Fox C; Schrager LK; et al; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, Md; 20892-1876.; BACKGROUND. In a small percentage of persons infected with human immunodeficiency virus type 1 (HIV-1), there is no progression of disease and CD4+ T-cell counts remain stable for many years. Studies of the histopathological, virologic, and immunologic characteristics of these persons may provide insight into the path
Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection [see comments]: N Engl J Med. 1995 Jan 26;332(4):228-32. Unique Identifier : AIDSLINE MED/95107362; Kirchhoff F; Greenough TC; Brettler DB; Sullivan JL; Desrosiers RC; New England Regional Primate Research Center, Harvard Medical; School, Southborough, Mass 01772-9102.
Images in clinical medicine. Human immunodeficiency virus [see comments]: N Engl J Med. 1995 Jan 26;332(4):233. Unique Identifier : AIDSLINE MED/95107363; Phillips DM
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 3-1995. A 29-year-old man with AIDS and multiple splenic abscesses [clinical conference]: N Engl J Med. 1995 Jan 26;332(4):249-57. Unique Identifier : AIDSLINE MED/95107366
Lessons from people with nonprogressive HIV infection [editorial; comment]: N Engl J Med. 1995 Jan 26;332(4):259-60. Unique Identifier : AIDSLINE MED/95107367; Baltimore D
Bronchiolitis obliterans with organizing pneumonia in AIDS [letter]: N Engl J Med. 1995 Jan 26;332(4):273. Unique Identifier : AIDSLINE MED/95107379; Joseph J; Harley RA; Frye MD
Enteroaggregative Escherichia coli as a possible cause of diarrhea in an HIV-infected patient [letter]: N Engl J Med. 1995 Jan 26;332(4):273-4. Unique Identifier : AIDSLINE MED/95107380; Mayer HB; Wanke CA
The Eiken Latex test for detection of a cryptococcal antigen in cryptococcosis. Comparison with a monoclonal antibody-based latex agglutination test, Pastorex Cryptococcus.: Mycopathologia. 1994 Sep;127(3):131-4. Unique Identifier : AIDSLINE MED/95107381; Tanaka K; Kohno S; Miyazaki T; Miyazaki H; Mitsutake K; Maesaki S; Kaku M; Koga H; Second Department of Internal Medicine, Nagasaki University; School of Medicine, Japan.; A latex agglutination test for cryptococcal antigen, the Eiken Latex test (Eiken, Tokyo, Japan ), was compared with a monoclonal antibody-based agglutination assay, Pastorex Cryptococcus (Diagnostics Pasteur, Marneur-la-Coquette, France ). In a mur
Update of Penicillosis marneffei in Thailand. Review article.: Mycopathologia. 1994 Sep;127(3):135-7. Unique Identifier : AIDSLINE MED/95107382; Imwidthaya P; Department of Microbiology, Faculty of Medicine, Siriraj; Hospital, Mahidol University, Bangkok, Thailand.; Penicillium marneffei is endemic in Southeast Asia. Although Thailand is a country in this region, penicillosis marneffei was rare. It was found occasionally in immunocompromised patients. With the increasing incidence of HIV seropositivity penicillosis marneffei emerged as one o
Treating HIV infection: a question of ethics [letter; comment]: N C Med J. 1994 Nov;55(11):512. Unique Identifier : AIDSLINE MED/95107389; Levine RH
Treating HIV infection: a question of ethics [letter; comment]: N C Med J. 1994 Nov;55(11):512. Unique Identifier : AIDSLINE MED/95107390; Pegram PS
[Rhodococcus equi pneumonia in patients with immunodeficiency]: Ned Tijdschr Geneeskd. 1994 Dec 24;138(52):2587-90. Unique Identifier : AIDSLINE MED/95107403; Borleffs JC; Petersen EJ; Kaasjager K; Teding van Berkhout F; Rozenberg-Arska M; Afd. Interne Geneeskunde, Academisch Ziekenhuis, Utrecht.; In three patients, men of 30, 21 and 24 years old respectively, Rhodococcus equi pneumonia was diagnosed. Antibiotic treatment, followed by secondary prophylaxis, was successful. In one patient, lobectomy was done. R. equi, a well-known bacterial pathogen in horses, appears also to be pathogenic in humans in case of i
Nocardial brain abscess: treatment strategies and factors influencing outcome.: Neurosurgery. 1994 Oct;35(4):622-31. Unique Identifier : AIDSLINE MED/95107481; Mamelak AN; Obana WG; Flaherty JF; Rosenblum ML; Department of Neurological Surgery, School of Medicine,; University of California, San Francisco.; The successful management of nocardial brain abscess remains problematic. The authors report 11 cases of nocardial brain abscess treated between 1971 and 1993 and review 120 cases reported since 1950. The clinical findings included focal deficits in 55 patients (42%), nonfocal findings in 36 (27%), and seizures in 39
Hypericin: a potential antiglioma therapy [published erratum appears in Neurosurgery 1994 Nov;35(5):993]: Neurosurgery. 1994 Oct;35(4):705-9; discussion 709-10. Unique Identifier : AIDSLINE MED/95107491; Couldwell WT; Gopalakrishna R; Hinton DR; He S; Weiss MH; Law RE; Apuzzo ML; Law RE; Department of Neurological Surgery, University of Southern; California School of Medicine, Los Angeles.; Hypericin, a polycyclic aromatic dione isolated from plants, is presently being clinically evaluated as an antiviral agent in the treatment of human immunodeficiency virus (HIV) infection. In addition, it is known to be a potent protein kinase C inhibitor. To evaluate its potential as an inhibitor of glioma growth, an
Hemophiliac class action suit.: N J Med. 1994 Nov;91(11):750. Unique Identifier : AIDSLINE MED/95107564; George JE; Weisfeld NE
A confusing issue [letter; comment]: N Y State Dent J. 1994 Nov;60(9):14. Unique Identifier : AIDSLINE MED/95107590; Kotlow LA
HIV status and confidentiality laws.: N Y State Dent J. 1994 Nov;60(9):22-4. Unique Identifier : AIDSLINE MED/95107591; Plunkett LR
Necrotizing retinitis in severe combined immunodeficiency mice following intracameral inoculation of herpes simplex virus type 1.: Ophthalmic Res. 1994;26(4):253-60. Unique Identifier : AIDSLINE MED/95107615; Minagawa H; Liu Y; Ishibashi T; Inomata H; Mori R; Department of Virology, Faculty of Medicine, Kyushu University,; Fukuoka, Japan.; Necrotizing retinitis in severe combined immunodeficiency (SCID) mice following intracameral inoculation of herpes simplex virus type 1 provided an experimental model for acute retinal necrosis in AIDS and other immunocompromised patients. In order to assess the involvement of the immunological response in the pathoge
Resistance and disease in Brugia malayi infection of ferrets following prior infection, injection of attenuated infective larvae and injections of larval extracts.: Parasite Immunol. 1994 Aug;16(8):425-33. Unique Identifier : AIDSLINE MED/95107654; Crandall R; Crandall C; Nayar J; Doyle T; Department of Immunology and Medical Microbiology, University of; Florida, Gainesville.; A partial resistance expressed by a 53% to 78% reduction in lymphatic filariae from a challenge infection was induced in ferrets (Mustela putorius furo) by a prior infection and by injection of radiation attenuated infective larvae (L3) but not by injections of lyophilized microfilariae (mf) or L3. Equivalent acquired
Cytokine profile of protective anti-Trichinella spiralis CD4+ OX22- and non-protective CD4+ OX22+ thoracic duct cells in rats: secretion of IL-4 alone does not determine protective capacity.: Parasite Immunol. 1994 Aug;16(8):435-45. Unique Identifier : AIDSLINE MED/95107655; Ramaswamy K; Goodman RE; Bell RG; James A. Baker Institute of Animal Health, New York State College; of Veterinary Medicine, Cornell University, Ithaca 14853.; We analysed the cytokine profile of a T cell subset (CD4+ CD45 RC-) that confers protection against Trichinella spiralis infection in rats. These CD4+ cells are generated in the gut and appear in the thoracic duct lymph within 72 h after infection. Cytokine mRNA levels for
Adoptive transfer of cloned T helper cells ameliorates periodontal disease in nude rats.: Oral Microbiol Immunol. 1994 Oct;9(5):284-9. Unique Identifier : AIDSLINE MED/95107661; Eastcott JW; Yamashita K; Taubman MA; Harada Y; Smith DJ; Department of Immunology, Forsyth Dental Center, Boston,; Massachusetts.; We have previously described a T helper cell 2-type clone, A3, of rat T cells that provides help for antibody production to Actinobacillus actinomycetemcomitans in vitro and in vivo in normal (euthymic) isogeneic Rowett strain recipient rats. Adoptive transfer of this T helper cell clone to euthymic rats also protects
[Aids-related cerebral lymphoma. Pathologic and immunohistochemical study of 19 cases]: Pathologica. 1994 Jun;86(3):247-52. Unique Identifier : AIDSLINE MED/95107685; Angeli G; Ramponi A; Ottinetti A; De Rosa G; Servizio di Anatomia Patologica, Ospedale S. Andrea, Vercelli.; We studied 19 cases of AIDS-related cerebral lymphomas, 15 of which are primary, and 4 secondary to systemic lymphoma. Eighteen cases are classified as non-Hodgkin s B cell lymphomas; in 1 case, an anaplastic large cell lymphoma coexists with systemic Hodgkin s disease. High-grade histologic types predominate (centrob
Respiratory distress caused by parasites.: Pediatr Ann. 1994 Aug;23(8):443-6. Unique Identifier : AIDSLINE MED/95107710; Wilson CM; Division of Pediatric Infectious Diseases, University of Alabama; at Birmingham.; Parasitic etiologies of pulmonary symptoms generally represent some degree of immunocompromise or occur as uncommon presentations of common parasitic infections. In regions where HIV infection is more prominent, PCP probably will be the most common parasitic respiratory disease seen. In geographic regions where helmin
A morphological study of chronic cerebral toxoplasmosis in mice: comparison of four different strains of Toxoplasma gondii.: Parasitol Res. 1994;80(6):493-501. Unique Identifier : AIDSLINE MED/95107910; Ferguson DJ; Huskinson-Mark J; Araujo FG; Remington JS; Nuffield Department of Pathology, University of Oxford, John; Radcliffe Hospital, UK.; The pathological changes, host-parasite relationship and structure of the tissue cysts in the brains of mice chronically infected with four different strains of Toxoplasma gondii were examined by light and electron microscopy. In mice infected with the mouse-adapted ME49 strain for 4, 8, 12, 16 and 25 weeks, the patho
Torsion angle differences as a means of pinpointing local polypeptide chain trajectory changes for identical proteins in different conformational states.: Protein Eng. 1994 Aug;7(8):961-7. Unique Identifier : AIDSLINE MED/95107949; Korn AP; Rose DR; Department of Medical Biophysics/Ontario Cancer Institute,; University of Toronto, Canada.; We discuss a facile and sensitive method of determining conformational differences based on the changes in the phi and psi angle values between chemically identical proteins in different conformations. It complements the conventional r.m.s. deviation technique, but offers some advantages. Two classes of conformational
Infection of vaginal and colonic epithelial cells by the human immunodeficiency virus type 1 is neutralized by antibodies raised against conserved epitopes in the envelope glycoprotein gp120.: Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12559-63. Unique Identifier : AIDSLINE MED/95107997; Furuta Y; Eriksson K; Svennerholm B; Fredman P; Horal P; Jeansson S; Vahlne A; Holmgren J; Czerkinsky C; Department of Clinical Virology, Goteborg University, Sweden.; The rectal and genital tract mucosae are considered to be major sites of entry for the human immunodeficiency virus (HIV) during sexual contact. We now demonstrate that vaginal epithelial cells can be infected by HIV type 1 (HIV-1) via a mechanism similar to that described for neuroglial cells and, more recently, for
Human T-cell leukemia virus type I Tax-protein-mediated activation of NF-kappa B from p100 (NF-kappa B2)-inhibited cytoplasmic reservoirs.: Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12634-8. Unique Identifier : AIDSLINE MED/95108012; Kanno T; Franzoso G; Siebenlist U; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.; The human T-cell leukemia virus type I Tax protein transforms T cells through induced expression of many cellular genes, including those encoding the growth-related proteins interleukin 2 and the alpha chain of its receptor. Induction of these genes is mediated, at least in part, through Tax-dependent posttranslationa
Propensity for a leucine zipper-like domain of human immunodeficiency virus type 1 gp41 to form oligomers correlates with a role in virus-induced fusion rather than assembly of the glycoprotein complex.: Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12676-80. Unique Identifier : AIDSLINE MED/95108021; Wild C; Dubay JW; Greenwell T; Baird T Jr; Oas TG; McDanal C; Hunter E; Matthews T; Department of Surgery, Duke University, Durham, NC 27710.; For a number of viruses, oligomerization is a critical component of envelope processing and surface expression. Previously, we reported that a synthetic peptide (DP-107) corresponding to the putative leucine zipper region (aa 553-590) of the transmembrane protein (gp41) of human immunodeficiency virus type 1 (HIV-1) e
Sleep patterns are disturbed in cats infected with feline immunodeficiency virus.: Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12947-51. Unique Identifier : AIDSLINE MED/95108075; Prospero-Garcia O; Herold N; Phillips TR; Elder JH; Bloom FE; Henriksen SJ; Department of Neuropharmacology, Scripps Research Institute, La; Jolla, CA 92037.; Human immunodeficiency virus (HIV)-related sleep disturbances have been reported early in AIDS. Likewise, the feline immunodeficiency virus (FIV), a natural lentivirus pathogen of cats, produces a similar immunodeficiency syndrome with neurological sequelae. To identify the neurophysiological substrate of FIV infectio
Metabolic suicide genes in gene therapy.: Pharmacol Ther. 1994 Aug;63(2):199-207. Unique Identifier : AIDSLINE MED/95108107; Mullen CA; Division of Cancer Biology, National Cancer Institute, National; Institutes of Health, Bethesda, MD 20892.; This article reviews uses of metabolic suicide genes in gene therapy. Suicide genes encode novel nonmammalian enzymes that can convert a relatively nontoxic prodrug into a highly toxic agent. Cells genetically transduced to express such genes essentially commit metabolic suicide in the presence of the appropriate prod
Tuberculosis in New York City's homeless population: a public health nightmare [see comments]: Pharos. 1994 Fall;57(4):2-8. Unique Identifier : AIDSLINE MED/95108110; Fusco M; Hospital of the University of Pennsylvania.
Tuberculosis epidemic: forgotten rules for its control [editorial; comment]: Pharos. 1994 Fall;57(4):32. Unique Identifier : AIDSLINE MED/95108113; Wassersug JD
Localized Mycobacterium avium-intracellulare mastitis in an immunocompetent woman with silicone breast implants.: Plast Reconstr Surg. 1995 Jan;95(1):142-4. Unique Identifier : AIDSLINE MED/95108155; Lee D; Goldstein EJ; Zarem HA; Department of Family Practice, Santa Monica Hospital Medical; Center, Calif.; While M. avium-intracellulare has received increasing recognition due to its association with AIDS, silicone breast implants have come under increased FDA scrutiny, requiring new safety and efficacy protocols. We report a case of localized M. avium-intracellulare mastitis associated w
Cognitive-behavioral and experiential group psychotherapy for HIV-infected homosexual men: a comparative study.: Psychosom Med. 1994 Sep-Oct;56(5):423-31. Unique Identifier : AIDSLINE MED/95108271; Mulder CL; Emmelkamp PM; Antoni MH; Mulder JW; Sandfort TG; de Vries MJ; Helen Dowling Institute for Biopsychosocial Medicine, Rotterdam,; The Netherlands.; The knowledge of being infected with the human immunodeficiency virus type 1 (HIV-1) brings about psychological distress and social problems including anxiety, depression, and social isolation. Participating in psychosocial intervention programs can help to reduce these problems. To date, however, very little is known
Pulmonary tuberculosis in overseas students of higher education is increasing in Edinburgh.: Respir Med. 1994 Oct;88(9):669-70. Unique Identifier : AIDSLINE MED/95108374; Faccenda J; Watt B; Leitch AG; Department of Medicine, University of Edinburgh, U.K.; In Edinburgh in 1991 a relative excess of pulmonary TB cases in the 15-34 year age group was recorded. Five of 17 notifications in this age group were of overseas students of higher education: three aged 21-29 from Central Africa, one 27-year-old Asian and one 26-year-old Western European. One of the African students
Laboratory and clinical aspects of the Mycobacterium avium epidemic: contributing factors associated with variability of drug susceptibility and immune responsiveness, and the multifaceted nature of pathogenicity.: Res Microbiol. 1994 Mar-Apr;145(3):167-8. Unique Identifier : AIDSLINE MED/95108403; Rastogi N; Barrow WW; Laboratoire de la Tuberculose et des Mycobacteries, Institut; Pasteur, Pointe-a-Pitre, Guadeloupe, French West Indies.
Epidemiology of Mycobacterium avium infections in the pre- and post-HIV era.: Res Microbiol. 1994 Mar-Apr;145(3):169-72. Unique Identifier : AIDSLINE MED/95108404; Falkinham JO 3rd; Department of Biology, Virginia Polytechnic Institute, State; University, Blacksburg 24061-0406.
Prevention and treatment of Mycobacterium avium complex infection.: Res Microbiol. 1994 Mar-Apr;145(3):181-7. Unique Identifier : AIDSLINE MED/95108407; Mangura BT; Reichman LB; University of Medicine and Dentistry of New Jersey, New Jersey; Medical School-National Tuberculosis Center, Department of; Medicine, University Hospital, Newark 07102.
Quantitative cultures and drug susceptibility testing of Mycobacterium avium clinical isolates before and during the antimicrobial therapy.: Res Microbiol. 1994 Mar-Apr;145(3):188-96. Unique Identifier : AIDSLINE MED/95108408; Heifets LB; National Jewish Center for Immunology and Respiratory Medicine,; Denver, CO 80206.
Clinical trials in Mycobacterium avium therapy: lessons to take home.: Res Microbiol. 1994 Mar-Apr;145(3):197-206. Unique Identifier : AIDSLINE MED/95108409; Dautzenberg B; Groupe hospitalier Pitie-Salpetriere, Paris.
Practical issues in the antibiotic and immunotherapy of Mycobacterium avium disease in immunocompromised patients.: Res Microbiol. 1994 Mar-Apr;145(3):206-9. Unique Identifier : AIDSLINE MED/95108410; Young LS; Bermudez LE; Inderlied CB; Kuzell Institute for Arthritis and Infectious Diseases,; California Pacific Medical Center Research Institute, San; Francisco 94115.
Immunomodulatory events in Mycobacterium avium infections.: Res Microbiol. 1994 Mar-Apr;145(3):225-9. Unique Identifier : AIDSLINE MED/95108413; Denis M; Departement d'anatomie et de biologie cellulaire, Universite de; Sherbrooke, Canada.
Mycobacterium avium: pathogenicity in HIV1 infection.: Res Microbiol. 1994 Mar-Apr;145(3):230-6. Unique Identifier : AIDSLINE MED/95108414; Shiratsuchi H; Johnson JL; Ellner JJ; Case Western Reserve University, University Hospital, Cleveland,; OH 44106.
[Tropical spastic paraparesis (HAM/TSP) in different regions of the world. Subclinical and geographic differences in neurophysiologic studies]: Rev Med Chil. 1994 Mar;122(3):265-73. Unique Identifier : AIDSLINE MED/95108454; Leon FE; Zaninovic V; Osame M; Arimura K; Arimura Y; Third Department of Internal Medicine, Kagoshima University; School of Medicine, Japan.; Tropical spastic paraparesis is the same clinical entity all over the world. It has been suggested that some clinical presentation differences are due to not well defined environmental factors that act along with the virus, modifying the start and progression of the disease. We analyzed 25 publications on the disease
The Duesberg phenomenon: what does it mean? [letter; comment]: Science. 1995 Jan 13;267(5195):157. Unique Identifier : AIDSLINE MED/95108559; Andrews C
The Duesberg phenomenon: what does it mean? [letter; comment]: Science. 1995 Jan 13;267(5195):157. Unique Identifier : AIDSLINE MED/95108560; Van Rompay K; Marthas ML
The Duesberg phenomenon: what does it mean? [letter; comment]: Science. 1995 Jan 13;267(5195):157-8. Unique Identifier : AIDSLINE MED/95108561; Strohman RC
The Duesberg phenomenon: what does it mean? [letter; comment]: Science. 1995 Jan 13;267(5195):158-9. Unique Identifier : AIDSLINE MED/95108562; Rubin H
The Duesberg phenomenon: what does it mean? [letter; comment]: Science. 1995 Jan 13;267(5195):159-60. Unique Identifier : AIDSLINE MED/95108564; Root-Bernstein RS
High turnover of HIV in blood revealed by new studies [news]: Science. 1995 Jan 13;267(5195):179. Unique Identifier : AIDSLINE MED/95108570; Cohen J
Will AIDS be contained within U.S. minority urban populations?: Soc Sci Med. 1994 Oct;39(8):1051-62. Unique Identifier : AIDSLINE MED/95108606; Wallace R; Fullilove M; Fullilove R; Gould P; Wallace D; Rutgers University Institute for Health.; Recent empirical research, and a simple stochastic modeling exercise, suggest that affluent suburban communities are at increased risk for the diffusion of HIV from present inner city epicenters, while the core group construct of sexually transmitted disease theory suggests, somewhat counter-intuitively, that the hy
Common childhood illnesses and HIV infection in Africa [letter]: S Afr Med J. 1994 May;84(5):296,298. Unique Identifier : AIDSLINE MED/95108740; Zumla A; Chintu C; Luo C
HIV testing in the insurance industry--the gap between theory and practice [letter] [see comments]: S Afr Med J. 1994 May;84(5):301-2. Unique Identifier : AIDSLINE MED/95108743; London L; Frieslaar J; Schelhase M
[Time for realism]: Tidsskr Nor Laegeforen. 1994 Nov 10;114(27):3212-4. Unique Identifier : AIDSLINE MED/95108828; Rosok B; Universitetet i Bergen.
Lymphocyte membrane modifications induced by HIV infection.: Tohoku J Exp Med. 1994 May;173(1):115-31. Unique Identifier : AIDSLINE MED/95108853; Kashiwagi N; Gill MJ; Adachi M; Church D; Wong SJ; Poon MC; Hakomori S; Tamaoki T; Shiozawa C; Department of Medical Biochemistry, Foothills Hospital,; University of Calgary, Alberta, Canada.; Novel carbohydrate antigen expressions were observed on T lymphocytes from HIV infected patients using flowcytometric analysis with four mAbs; BM-1, ACFH-18, FH-2 and C-6. These carbohydrate antigens were also expressed on oncogenic transformed cells but were either not expressed or were weakly expressed in lymphocyte
Graft-versus-host reaction and GvH disease.: Tohoku J Exp Med. 1994 May;173(1):171-81. Unique Identifier : AIDSLINE MED/95108858; Harada T; Department of Pathology I, Shimane Medical University, Izumo,; Japan.; Chronic GvHR was induced by inoculating parental lymphoid cells into F1 hybrid mouse. Combination of ATL and ATH, which were congenic recombinant strains differing only in H-2I and S region from each other, was chosen to induce class II-GvHR. Selective activation against partner s alloantigen of graft CD4+ T cells was
The role of T cell subsets in regulating the in vivo efficacy of CTLA4-Ig in preventing graft-versus-host disease in recipients of fully MHC or multiple minor histocompatibility-disparate donor inocula.: Transplantation. 1994 Dec 27;58(12):1422-6. Unique Identifier : AIDSLINE MED/95108896; Blazar BR; Taylor PA; Gray GS; Vallera DA; Department of Pediatrics, University of Minnesota Hospital and; Clinic, Minneapolis 55455.
Does the HIV-1 coat protein gp120 produce brain damage? [letter]: Trends Pharmacol Sci. 1994 Oct;15(10):362-3. Unique Identifier : AIDSLINE MED/95108910; Bagetta G; Corasaniti TM; Finazzi-Agro A; Nistico G
[Localization of the CD4 receptor gene in the chromosomes of clone cells of the monocytoid line U-937 characterized by different sensitivities to HIV]: Tsitologiia. 1994;36(1):71-4. Unique Identifier : AIDSLINE MED/95108921; Glukhova LA; Kushch AA; Mamaeva SE; Zverev VV; Tsvetkova TG; Liapunova NA; Karyotypes of two clones of U-937 line, with high and low sensitivity to HIV-1, were studied. The CD4-receptor gene-cellular receptor of HIV-1 was mapped. CD4-receptor gene was located according to in situ hybridization method, in locus 12 p11-p12, both in cells of high-sensitive clone U-937/16, and in cells of low-se
Submicroscopic profile of Isospora belli enteritis in a patient with acquired immune deficiency syndrome.: Ultrastruct Pathol. 1994 Sep-Oct;18(5):473-82. Unique Identifier : AIDSLINE MED/95108957; Comin CE; Santucci M; Institute of Anatomic Pathology, University of Florence Medical; School, Italy.; Small bowel mucosal fragments from a human immunodeficiency virus-positive female patient with chronic diarrhea were investigated by transmission electron microscopy, and Isospora belli enteritis was documented. The submicroscopic profile was characterized by a moderate abnormality of mucosal architecture with reducti
Ultrastructural pathology of human T-cell lymphotropic virus type I encephalomyelopathy in a white patient with adult T-cell leukemia/lymphoma.: Ultrastruct Pathol. 1994 Sep-Oct;18(5):511-8. Unique Identifier : AIDSLINE MED/95108962; Liberski PP; Rodgers-Johnson P; Yanagihara R; Lee JW; Kramer BS; Piccardo P; Mora CA; Gibbs CJ Jr; Gajdusek DC; Laboratory of Central Nervous System Studies, National Institute; of Neurological Disorders and Stroke, National Institutes of; Health, Bethesda, Maryland 20892.; A white patient with human T-cell lymphotropic virus type I (HTLV-I)-associated adult T-cell leukemia/lymphoma for 10 years died 4 months after the onset of spastic myelopathy. Ultrastructurally, the neuropathologic findings consisted of dystrophic neurites (spheroids) filled with neurofilaments or electron-dense bodi
Autologous red cell agglutination test for antibodies to feline immunodeficiency virus.: Vet Immunol Immunopathol. 1994 Sep;42(3-4):253-63. Unique Identifier : AIDSLINE MED/95109047; Wilson KM; Robinson WF; Mitchelhill KI; Bundesen PG; Kemp BE; St. Vincent's Institute of Medical Research, Fitzroy, Vic.,; Australia.; The T-lymphotropic lentivirus, feline immunodeficiency virus (FIV) is now recognised as a major viral pathogen affecting domestic cat populations worldwide. A rapid, autologous red cell agglutination test for antibodies to FIV has been developed. A synthetic peptide analog corresponding to the immunodominant epitope w
The acquired immunodeficiency syndrome in older persons [letter]: West J Med. 1994 Nov;161(5):526. Unique Identifier : AIDSLINE MED/95109131; Rozance CP; Kizer KW
[Drug fatalities from the forensic medicine viewpoint. 10 years experiences of the Vienna Institute of Forensic Medicine]: Wien Klin Wochenschr. 1994;106(21):677-80. Unique Identifier : AIDSLINE MED/95109146; Risser D; Bonsch A; Schneider B; Vycudilik W; Bauer G; Institut fur Gerichtliche Medizin, Universitat Wien.; The problem of illicit drug abuse has of course not spared Austria . In fact, considering only the increase in the official figures on drug-related deaths over the past few years, this problem has dramatically worsened in Austria. Drug-related deaths represent the most serious cons
The effects of azidothymidine therapy on pseudocholinesterase concentrations in asymptomatic HIV-positive patients.: AANA J. 1994 Aug;62(4):337-41. Unique Identifier : AIDSLINE MED/95109282; Barker GM; Holland C; Katz JA; The purpose of this study was to determine if a correlation exists between long-term azidothymidine ( AZT ) therapy and low pseudocholinesterase concentrations in patients who are infected with the human immunodeficiency virus (HIV). A pilot study was c
Influence of management technology and parturition on antibody levels in cows with bovine leukosis.: Acta Vet Hung. 1994;42(1):57-67. Unique Identifier : AIDSLINE MED/95109405; Tekes L; Central Veterinary Institute, Budapest, Hungary.; Sera from 97 Holstein-Friesian cows kept in isolation (herd I) were tested on 9 occasions with an interval of 90 days. The cows had previously given a positive reaction with bovine leukaemia virus antigen in the agar gel immunodiffusion (AGID) test. During the period of loose housing (at tests 1-3) 0-3 cows per test (
Eradication of bovine leukosis from a heavily infected herd by the use of own offspring.: Acta Vet Hung. 1994;42(4):421-32. Unique Identifier : AIDSLINE MED/95109445; Meszaros J; Antal T; Polner AT; Sumeghy L; Szabo I; Vajda G; Veterinary Medical Research Institute, Hungarian Academy of; Sciences, Budapest.; In a Holstein-Friesian dairy herd (n = 1,248) kept in loose housing system and showing 62% prevalence of infection with bovine leukosis virus (BLV), the newborn calves were separated from their dams and placed into individual pens. They were given freeze-stored colostrum derived from a BLV-free farm and then a calf st
[Markers in the evolution and control of HIV infection]: An R Acad Nac Med (Madr). 1994;111(2):273-87. Unique Identifier : AIDSLINE MED/95109877; Piedrola Angulo G
[Apoptosis in HIV infection]: An R Acad Nac Med (Madr). 1994;111(2):289-311; discussion 311-6. Unique Identifier : AIDSLINE MED/95109878; Maroto Vela M del C
Prevention across the life span: healthy people for the twenty-first century.: ANA Publ. 1993 Nov;(CH-27 5M):ix-x. Unique Identifier : AIDSLINE MED/95109885; Hinshaw AS; Heinrich J
Children: a community in crisis.: Am Nurse. 1994 Nov-Dec;26(10):1, 20-1. Unique Identifier : AIDSLINE MED/95109965; Cassetta RA
Profession mourns loss of Barbara Fassbinder.: Am Nurse. 1994 Nov-Dec;26(10):3. Unique Identifier : AIDSLINE MED/95109973
Host-directed and immune-based therapies for human immunodeficiency virus infection [see comments]: Ann Intern Med. 1995 Feb 1;122(3):218-22. Unique Identifier : AIDSLINE MED/95109986; Lederman MM; Department of Medicine, University Hospitals of Cleveland, OH; 44106.; This essay reviews the rationale underlying host-directed or immune-based therapeutic strategies for human immunodeficiency virus (HIV) infection and its complications. These approaches have seen only limited trial in the past 10 years, but as more is learned about the immunopathogenesis of HIV disease and as the limi
Clinical research in the acquired immunodeficiency syndrome [editorial; comment]: Ann Intern Med. 1995 Feb 1;122(3):232-3. Unique Identifier : AIDSLINE MED/95109990; Powderly WG
Selective inhibition of topoisomerases from Pneumocystis carinii compared with that of topoisomerases from mammalian cells.: Antimicrob Agents Chemother. 1994 Sep;38(9):1890-8. Unique Identifier : AIDSLINE MED/95110042; Dykstra CC; McClernon DR; Elwell LP; Tidwell RR; Department of Pathology, University of North Carolina at Chapel; Hill 27599.; Type I and II topoisomerase activities were partially purified from Pneumocystis carinii. The catalytic (strand-passing) activities of both enzymes were selectively inhibited by members of a series of dicationic-substituted bis-benzimidazoles compared with those of topoisomerases of mammalian (calf thymus) origin. The
Assays to detect and characterize human immunodeficiency virus type 1 (HIV-1) receptor antagonists, compounds that inhibit binding of the HIV-1 surface glycoprotein, gp120, to the CD4 receptor on human T lymphocytes.: Antimicrob Agents Chemother. 1994 Sep;38(9):2008-13. Unique Identifier : AIDSLINE MED/95110060; Clancy J; Tait-Kamradt A; Petitpas J; Manousos M; McGuirk PR; Subashi T; Watts P; Wondrack L; Central Research Division, Pfizer, Inc., Groton, Connecticut; 06340.; Human immunodeficiency virus type 1 infects human helper T lymphocytes by an interaction between gp120, the viral coat protein, and the T-cell receptor CD4. Two microtiter-based immunoassays, an enzyme-linked immunosorbent assay (ELISA) and a particle concentration fluorescence assay, were developed to measure gp120-C
Antiprotozoal activities of benzimidazoles and correlations with beta-tubulin sequence.: Antimicrob Agents Chemother. 1994 Sep;38(9):2086-90. Unique Identifier : AIDSLINE MED/95110072; Katiyar SK; Gordon VR; McLaughlin GL; Edlind TD; Medical College of Pennsylvania, Philadelphia 19129.; Benzimidazoles have been widely used since the 1960s as anthelmintic agents in veterinary and human medicine and as antifungal agents in agriculture. More recently, selected benzimidazole derivatives were shown to be active in vitro against two protozoan parasites, Trichomonas vaginalis and Giardia lamblia, and clinic
Low-dose dexamethasone as adjunctive therapy for disseminated Mycobacterium avium complex infections in AIDS patients.: Antimicrob Agents Chemother. 1994 Sep;38(9):2215-7. Unique Identifier : AIDSLINE MED/95110101; Wormser GP; Horowitz H; Dworkin B; Division of Infectious Diseases, Westchester County Medical; Center, Valhalla, New York.; Five human immunodeficiency virus-infected patients with disseminated Mycobacterium avium complex infection had progressive weight loss and persistent fever despite multidrug antimycobacterial therapy. These patients were given daily low-dose oral dexamethasone (typically 2 mg/day) as adjunctive therapy. All had subst
Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes.: Antiviral Res. 1994 Sep;25(1):13-25. Unique Identifier : AIDSLINE MED/95110107; Zelphati O; Wagner E; Leserman L; Centre d'Immunologie, Institut National de la Sante et de la; Recherche Medicale, Centre National de la Recherche Scientifique; de Marseille, France.; Encapsulation of oligonucleotides in antibody-targeted liposomes (immunoliposomes) which bind to target cells permits intracellular delivery of the oligonucleotides. This approach circumvents problems of extracellular degradation by nucleases and poor membrane permeability which free phosphodiester oligonucleotides ar
Unrecognized human immunodeficiency virus infection in the elderly.: Arch Intern Med. 1995 Jan 23;155(2):184-6. Unique Identifier : AIDSLINE MED/95110182; el-Sadr W; Gettler J; Department of Medicine, Harlem Hospital Center, New York, NY.; BACKGROUND: Human immunodeficiency virus (HIV) infection among the elderly has not been appreciated in the United States . This is the result of their exclusion from targeted HIV-testing programs and the perception that they were not at significant risk. METHODS: To assess the extent of
Oral mucosal ulceration due to cytomegalovirus associated with human immunodeficiency virus infection. Case report and brief review.: Aust Dent J. 1994 Oct;39(5):273-5. Unique Identifier : AIDSLINE MED/95110256; Firth NA; Rich AM; Reade PC; University of Melbourne.; Reports of oral lesions associated with cytomegalovirus ( CMV ) infection in human immunodeficiency virus (HIV) infected patients are uncommon. In this article a case of CMV infection associated with oral mucosal ulceration and
HIV infection and the dentist ... costs [letter; comment]: Aust Dent J. 1994 Oct;39(5):329. Unique Identifier : AIDSLINE MED/95110272; Bowell G
Aetiology and pathogenesis of hormonal and metabolic disorders in HIV infection.: Baillieres Clin Endocrinol Metab. 1994 Oct;8(4):735-55. Unique Identifier : AIDSLINE MED/95110274; Grinspoon SK; Donovan DS Jr; Bilezikian JP; Massachusetts General Hospital, Neuroendocrine Unit, Boston; 02114.; Many hormonal and metabolic disturbances are documented in HIV infection, the most important of which is the wasting syndrome associated with progressive HIV infection. We are only now beginning to understand the pathogenesis of these disturbances. In rare cases, infiltration of endocrine tissue by secondary infectiou
Hypothalamic and pituitary function in AIDS.: Baillieres Clin Endocrinol Metab. 1994 Oct;8(4):757-67. Unique Identifier : AIDSLINE MED/95110275; Merenich JA; Division of Endocrinology, Metabolism & Diabetes, University of; Colorado, Health Sciences Center, Denver 80262.; Clinically relevant HP dysfunction occurs infrequently in the course of HIV infection and AIDS, and is usually due to destruction or infiltration of the region by opportunistic infections. However, more subtle defects occur with much greater frequency. Since these impairments, especially in the gonadotrophic and corti
Adrenal complications of HIV infection.: Baillieres Clin Endocrinol Metab. 1994 Oct;8(4):769-76. Unique Identifier : AIDSLINE MED/95110276; Opocher G; Mantero F; Instituto di Semeiotica Medica, Padua, Italy.
The syndrome of acquired glucocorticoid resistance in HIV infection.: Baillieres Clin Endocrinol Metab. 1994 Oct;8(4):777-87. Unique Identifier : AIDSLINE MED/95110277; Norbiato G; Galli M; Righini V; Moroni M; Luigi Sacco Hospital, Milan, Italy.; A certain number of HIV-infected patients (about 17% in our series) manifest symptoms of cortisol resistance--weakness, weight loss, hypertension, chronic fatigue and intense mucocutaneous melanosis--symptoms which are also typical of Addison s disease. The diagnosis of cortisol resistance is determined through the in
Glucocorticoids and the immune system in AIDS.: Baillieres Clin Endocrinol Metab. 1994 Oct;8(4):789-802. Unique Identifier : AIDSLINE MED/95110278; Vago T; Clerici M; Norbiato G; Department of Endocrinology, Luigi Sacco Hospital, Milan, Italy.; Data reported in the literature show in the majority of cases an increased basal cortisol level in HIV-positive patients compared with controls, although the plasma concentration of cortisol in HIV-positive patients is generally within the physiological range. It is well known that pharmacological doses of glucocortic
Steroid hormone, cytokine, lipid and metabolic disturbances in HIV infection.: Baillieres Clin Endocrinol Metab. 1994 Oct;8(4):803-24. Unique Identifier : AIDSLINE MED/95110279; Nunez EA; Christeff N; Department of Clinical Biochemistry, Hopital X. Bichat, Paris,; France.
Thyroid dysfunction in HIV infection.: Baillieres Clin Endocrinol Metab. 1994 Oct;8(4):825-35. Unique Identifier : AIDSLINE MED/95110280; Lambert M; Division of General Internal Medicine, Saint-Luc University; Hospital, Catholic University of Louvain Medical School,; Brussels, Belgium.; During infection with HIV, overt clinical or biochemical thyroid dysfunctions are rare. When present, thyroid failure generally results from the destruction of the thyroid gland by opportunistic infections such as Pneumocystis carinii, or tumoural processes such as KS. Less frequently, hypothalamic-pituitary failure d
Hyponatraemia in AIDS.: Baillieres Clin Endocrinol Metab. 1994 Oct;8(4):837-48. Unique Identifier : AIDSLINE MED/95110281; Bevilacqua M; Department of Endocrinology, Luigi Sacco Hospital, Milan, Italy.; Hyponatraemia is very common in AIDS patients. It is observed in about 40-50% of hospitalized patients. It may contribute to overall mortality in advanced disease. Vasopressin measurements in these patients basically present two distinct syndromes: hyponatraemia and normal vasopressin levels (i.e. measurable vasopre
Gonadal function in AIDS.: Baillieres Clin Endocrinol Metab. 1994 Oct;8(4):849-57. Unique Identifier : AIDSLINE MED/95110282; Maggi M; Forti G; Andrology Unit, USL 10 D, Florence, Italy.
Pancreatic lesions in HIV-infected patients.: Baillieres Clin Endocrinol Metab. 1994 Oct;8(4):859-77. Unique Identifier : AIDSLINE MED/95110283; Brivet FG; Naveau SH; Lemaigre GF; Dormont J; Department of Intrernal Medicine, Hopital Antoine Beclere,; Clamart, France.; The pancreas is frequently involved during HIV infection, especially by disseminated infections or neoplasms. These lesions are generally asymptomatic and are discovered at autopsy. However, hypoglycaemia secondary to massive pancreatic infiltration by a tumour or tuberculous necrosis may occur. The most important cau
DNA topoisomerases I & II cleavage sites in the type 1 human immunodeficiency virus (HIV-1) DNA promoter region.: Biochem Biophys Res Commun. 1994 Dec 30;205(3):1601-9. Unique Identifier : AIDSLINE MED/95110298; Pommier Y; Poddevin B; Gupta M; Jenkins J; Laboratory of Molecular Pharmacology, National Cancer Institute,; NIH, Bethesda, MD 20892.; Topoisomerase sites were mapped in the 5 -long terminal repeat of HIV-1 DNA by agarose and sequencing gel electrophoresis. Topoisomerase II sites were observed in the absence and presence of teniposide and amsacrine in the transcription initiation region and the TATA box, consistent with a possible role of topoisomera
Construction of infectious molecular clones of HIV-1 containing defined mutations in the protease gene.: Biochem Biophys Res Commun. 1994 Dec 30;205(3):1651-7. Unique Identifier : AIDSLINE GENBANK/K03455; Winslow DL; Anton ED; Horlick RA; Zagursky RJ; Tritch RJ; Scarnati H; Ackerman K; Bacheler LT; DuPont Merck Pharmaceutical Company, Wilmington, DE 19880-0026.; A DNA clone of HIV-1 containing the full-length infectious viral sequence was cleaved at a unique Nco I restriction site within the viral genome, and DNA fragments containing the 5 and 3 portions of the HIV genome were subcloned into separate plasmid vectors. The 5 half-virus construct was further modified by inc
Rapid grouping of HIV-1 infection in subtypes A to E by V3 peptide serotyping and its relation to sequence analysis.: Biochem Biophys Res Commun. 1994 Dec 30;205(3):1658-64. Unique Identifier : AIDSLINE MED/95110306; Sherefa K; Sonnerborg A; Steinbergs J; Sallberg M; Department of Immunology, Karolinska Institutet, Huddinge; University Hospital, Sweden.; We developed a typing assay for HIV-1 using subtype specific peptides corresponding to the five major subtypes of HIV-1 (A to E). In eight patients serologically subtyped as A (n = 1), B (n = 3), C (n = 3) and E (n = 1) phyllogenetic analysis of sequenced V3 domain DNA completely correlated to the peptide serotyping.
Structure-activity relationships of an anti-HIV peptide, T22.: Biochem Biophys Res Commun. 1994 Dec 30;205(3):1729-35. Unique Identifier : AIDSLINE MED/95110316; Tamamura H; Murakami T; Masuda M; Otaka A; Takada W; Ibuka T; Nakashima H; Waki M; Matsumoto A; Yamamoto N; et al; Faculty of Pharmaceutical Sciences, Kyoto University, Japan.; T22 ([Tyr5,12,Lys7]-polyphemusin II) has been shown to have a strong anti-human immunodeficiency virus (HIV) activity comparable to that of 3 -azido-2 ,3 -dideoxythymidine ( AZT ). We studied the structure-anti-HIV activity relationships of T22 and dete
Membrane orientation of the SIV fusion peptide determines its effect on bilayer stability and ability to promote membrane fusion.: Biochem Biophys Res Commun. 1994 Dec 30;205(3):1938-43. Unique Identifier : AIDSLINE MED/95110345; Epand RF; Martin I; Ruysschaert JM; Epand RM; Department of Biochemistry, McMaster University Health Sciences; Centre, Hamilton, Ontario, Canada.; The amino terminal segment of the gp32 glycoprotein of SIV has been identified as an important region for membrane fusion. A synthetic dodecapeptide corresponding to this amino terminal segment, SIVwt, can promote the fusion of liposomes. This peptide inserts at an oblique angle into the membrane. If the amino acid se
Activation of human T helper 1 and DNAase expression in CD4+ T cells induced by short immunomodulating peptides.: Biochem Biophys Res Commun. 1994 Dec 30;205(3):2008-12. Unique Identifier : AIDSLINE MED/95110354; Lopez-Moratalla N; Migliacio M; Lopez-Zabalza MJ; Perez-Mediavilla LA; Santiago E; Department of Biochemistry, University of Navarra, Pamplona,; Spain.; Activation of human T helper 1 cells took place when lymphomononuclear cells from healthy donors were incubated in the presence of short synthetic peptides encompassing sequences present in extracellular matrix proteins. Active peptides conformed to a common structural pattern (2-6-11 motif) [N.Lopez-Moratalla et al.,
Rapid inactivation of HIV-1 in single donor preparations of human fresh frozen plasma by methylene blue/light treatment.: Biologicals. 1994 Sep;22(3):227-31. Unique Identifier : AIDSLINE MED/95110535; Lambrecht B; Norley SG; Kurth R; Mohr H; German Red Cross, Springe.; Human fresh frozen plasma (FFP) was spiked with highly titered HIV-1 and illuminated with visible light in the presence of 1 microM of the photoactive dye methylene blue (MB). As shown by titration on MT-4 cells, the infectivity of the virus containing plasma was rapidly lost during illumination: after 5 min the infec
Cellular distribution of HIV type 1 Nef protein: identification of domains in Nef required for association with membrane and detergent-insoluble cellular matrix.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):1003-10. Unique Identifier : AIDSLINE MED/95110624; Kaminchik J; Margalit R; Yaish S; Drummer H; Amit B; Sarver N; Gorecki M; Panet A; Biotechnology General, Ltd., Kiryat Weizmann Rehovot, Israel.; Cellular distribution of HIV-1 Nef protein was studied by expressing the protein in mammalian cells. Cell extracts were fractionated by low- and high-speed centrifugation and by nonionic detergents. Two Nef-related proteins were expressed in COS cells, Nef-27kD and Nef-25kD. Nef-27kD, an N-myristoylated form of Nef, w
Immunogenicity of Nef protein of SIVSMM-PBj14 expressed in a live vaccine strain of Salmonella species.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):1011-9. Unique Identifier : AIDSLINE MED/95110625; Cattozzo EM; Stocker BA; Department of Microbiology and Immunology, Stanford University; School of Medicine, California 94305.; The nef gene of an infectious molecular clone of SIVSMM isolate PBj14 was fused to the glutathione S-transferase gene of Schistosoma japonicum to generate plasmid pEMC100. The recombinant plasmid was placed in an aroA live vaccine Salmonella dublin strain, and the production of GST-Nef protein was induced by exposure
Persistent infection with SIVmac chimeric virus having tat, rev, vpu, env and nef of HIV type 1 in macaque monkeys.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):1021-9. Unique Identifier : AIDSLINE MED/95110626; Igarashi T; Shibata R; Hasebe F; Ami Y; Shinohara K; Komatsu T; Stahl-Hennig C; Petry H; Hunsmann G; Kuwata T; et al; Institute for Virus Research, Kyoto University, Japan.; A chimeric human and simian immunodeficiency virus carrying the tat, rev, vpu, env, and nef genes of human immunodeficiency virus type 1 was generated. The chimeric virus, NM-3n, grew competently in peripheral blood mononuclear cells from cynomolgus monkeys like the parental SIVmac. Two cynomolgus monkeys and one rhes
HIV type 2 proviral load measured by quantitative polymerase chain reaction correlates with CD4+ lymphopenia in HIV type 2-infected individuals.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):1031-7. Unique Identifier : AIDSLINE GENBANK/M15390; Berry N; Ariyoshi K; Jobe O; Ngum PT; Corrah T; Wilkins A; Whittle H; Tedder R; Division of Virology, University College London Medical School,; England.; The efficiency of detection of 2 sets of primer pairs from putatively conserved regions of the human immunodeficiency virus type 2 (HIV-2) genome were assessed in 86 seropositive individuals from The Gambia by nested polymerase chain reaction (PCR). HIV-2 long terminal repeat (LTR)
Presence in India of HIV type 1 similar to North American strains.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):1039-41. Unique Identifier : AIDSLINE GENBANK/L29094; Baskar PV; Ray SC; Rao R; Quinn TC; Hildreth JE; Bollinger RC; Department of Pharmacology and Molecular Sciences, Johns Hopkins; University, Baltimore, Maryland 21205.
p17gag sequence of HIV-1GER, a new, highly replicative and highly cytopathic HIV type 1 strain of D genotype.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):1043-5. Unique Identifier : AIDSLINE GENBANK/U11549; Emiliani S; Blanc M; Devaux C; CRBM-UPR 9008 du CNRS, Montpellier.
Keynote address: variations in the natural history of HIV infection.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):883-5. Unique Identifier : AIDSLINE MED/95110630; Phair JP; Department of Medicine, Northwestern University School of; Medicine, Chicago, Illinois 60611.; In general, the natural history of HIV infection as revealed by prospective cohort studies such as the Multicenter AIDS Cohort Study (MACS) is consistent with our current understanding of the immunopathogenesis of HIV disease. Although the limitations of CD4+ T cell counts as a predictor of response to therapy are now
Evolving understanding of the immunopathogenesis of HIV.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):887-92. Unique Identifier : AIDSLINE MED/95110631; Saag MS; Department of Medicine, University of Alabama at Birmingham; 35294.; Understanding of the immunopathogenesis of HIV infection is becoming more advanced as the activity of HIV infection in lymph nodes is appreciated and as improved virological measures permit more accurate quantitation of viral burden in patients at all stages of HIV disease. Although CD4+ cell counts remain important p
Early intervention in HIV infection: where are we?: AIDS Res Hum Retroviruses. 1994 Aug;10(8):893-9. Unique Identifier : AIDSLINE MED/95110632; Collier AC; Department of Medicine, University of Washington School of; Medicine, Seattle.; Data about the virology and pathogenesis of HIV disease suggest that early therapeutic intervention, perhaps even before the CD4+ cell count has fallen substantially, would be a theoretically sound approach. A limited number of large clinical studies address early therapy with zidovudine. A European-Australian study,
Resistance, drug failure, and disease progression.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):901-5. Unique Identifier : AIDSLINE MED/95110633; Richman DD; Department of Pathology, University of California at San Diego,; La Jolla 92093-0679.; The clinical significance of the reduced in vitro susceptibility of HIV to antiretroviral agents has been difficult to elucidate for nucleoside analogs such as zidovudine. However, the virological significance of resistance to nevirapine and other HIV
Combination therapy: more effective control of HIV type 1?: AIDS Res Hum Retroviruses. 1994 Aug;10(8):907-12. Unique Identifier : AIDSLINE MED/95110634; Johnson VA; Department of Medicine, University of Alabama at Birmingham.; The rationale for combining anti-HIV-1 agents is to provide more complete viral suppression, to limit the emergence of drug resistance during chronic viral replication, and to provide more effective antiretroviral treatment even when mixtures of drug-resistant and drug-sensitive strains are present. In vitro experimen
Disseminated Mycobacterium avium complex disease in patients with AIDS.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):913-6. Unique Identifier : AIDSLINE MED/95110635; Benson C; Section of Infectious Disease, Rush Medical College, Chicago,; Illinois 60612.; Disseminated Mycobacterium avium complex (MAC) infection is a common complication of advanced HIV disease that is associated with significant morbidity. After diagnosis of MAC by recovery of organisms from blood or other normally sterile sites, specific treatment with multiple-drug regimens is appropriate and may redu
Current management of cytomegalovirus disease in patients with AIDS.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):917-23. Unique Identifier : AIDSLINE MED/95110636; Jacobson MA; Department of Medicine, University of California at San; Francisco, 94110.; Cytomegalovirus ( CMV ) infection is common in both homosexual and heterosexual HIV-infected patients, and causes disease in a substantial proportion of patients with AIDS and very low CD4+ cell counts. Both ganciclovir, an analog of the nucleoside guanosine, and
Resistant candidiasis.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):925-9. Unique Identifier : AIDSLINE MED/95110637; Powderly WG; Division of Infectious Diseases, Washington University School of; Medicine, St. Louis, Missouri 63110.; Mucosal (oropharyngeal, esophageal, and, in women, vaginal) candidiasis is a common infectious complication in HIV-infected patients. There is a wide range of drugs to treat or suppress Candida infections. However, with the increasingly common use of fluconazole as treatment or prophylaxis in patients with relatively
Wasting syndrome: nutritional support in HIV infection.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):931-4. Unique Identifier : AIDSLINE MED/95110638; Kotler DP; Department of Medicine, Columbia University of College of; Physicians and Surgeons, New York, New York 10025.; Malnutrition and wasting are common in patients with HIV infection. Nutritional needs vary with the stage of HIV disease. Severe weight loss is associated with increased mortality in patients with AIDS and is multifactorial in development. Possible causes of weight loss include decreased food intake due to oral or GI
Management of the female HIV-infected patient.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):935-8. Unique Identifier : AIDSLINE MED/95110639; Baker DA; Department of Obstetrics and Gynecology, HSC State University of; New York at Stony Brook 11794-8091.; Management of women with HIV infection or AIDS should follow the established guidelines for antiretroviral therapy and prevention and treatment of opportunistic complications of HIV infection. Gynecological manifestations of HIV are primarily cervical dysplasia and cancer associated with human papillomavirus (HPV) inf
Glutathione precursor and antioxidant activities of N-acetylcysteine and oxothiazolidine carboxylate compared in in vitro studies of HIV replication.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):961-7. Unique Identifier : AIDSLINE MED/95110643; Raju PA; Herzenberg LA; Herzenberg LA; Roederer M; Department of Genetics, Beckman Center B007, Stanford University; Medical School, California 94305-5125.; N-Acetyl-L-cysteine (NAC) and L-2-oxothiazolidine 4-carboxylate (OTC) are pro-GSH drugs that been proposed for AIDS therapy. In this article we compare the antiviral activities of these compounds in various in vitro HIV infection models. Although both compounds blocked cytokine induction of HIV in acute and chronic in
Inhibition of AIDS-associated Kaposi's sarcoma cell growth by DAB389-interleukin 6.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):969-75. Unique Identifier : AIDSLINE MED/95110644; Masood R; Lunardi-Iskandar Y; Jean LF; Murphy JR; Waters C; Gallo RC; Gill P; Department of Internal Medicine, University of Southern; California School of Medicine, Los Angeles 90033.; Acquired immune deficiency syndrome-associated Kaposi s sarcoma (AIDS-KS)-derived spindle cells produce and use interleukin 6 (IL-6) among several other cytokines as a growth factor. In this study we show that AIDS-KS cells express approximately 1100 high-affinity IL-6 receptors (IL-6R) per cell with a dissociation co
Prospective utility of cerebral proton magnetic resonance spectroscopy in monitoring HIV infection and its associated neurological impairment.: AIDS Res Hum Retroviruses. 1994 Aug;10(8):977-82. Unique Identifier : AIDSLINE MED/95110645; McConnell JR; Swindells S; Ong CS; Gmeiner WH; Chu WK; Brown DK; Gendelman HE; Department of Radiology, University of Nebraska Medical Center,; Omaha 68198.; Neurological manifestations of HIV disease occur in most adults and children with AIDS. Many of those affected will inevitably suffer clinical neurological deficits involving mental function, movement, and sensation. Surprisingly, there are not as yet adequate monitoring systems to predict the onset and/or progression
Oral cancer education and HIV-associated malignancies.: J Cancer Educ. 1994 Fall;9(3):152-4. Unique Identifier : AIDSLINE MED/95110707; Silverman S Jr; School of Dentistry, University of California, San Francisco; 94143.; Interest and participation in oral cancer education courses has been disappointingly low, probably because of the sparsity and low impact of cases of oral cancer relative to clinical practice. Interest and participation increase as subject matter relevant to clinical practice is included to create innovative programs.
Increased fears of HIV and bovine TB link [interview by Dina Leifer]: Nurs Stand. 1994 Nov 2-8;9(6):11. Unique Identifier : AIDSLINE MED/95110715; Grange J
HIV mortality linked to income [news]: Nurs Stand. 1994 Nov 2-8;9(6):12. Unique Identifier : AIDSLINE MED/95110716; Hogg RS
NHS market reforms: lessons from the US.: Nurs Stand. 1994 Nov 2-8;9(6):31-4. Unique Identifier : AIDSLINE MED/95110722; Smith P; Since their inception, the reforms of the National Health Service have been described by some commentators as having great similarities with the kind of healthcare services offered in the US. With the assistance of a Fulbright Scholarship, the author visited the US in 1993 to study the services offered there. This art
HVA launches new guidance booklet on AIDS and HIV [news]: Nurs Stand. 1994 Nov 2-8;9(6):8. Unique Identifier : AIDSLINE MED/95110727
Doctor's HIV comments 'insensitive' say nurses [news]: Nurs Stand. 1994 Nov 23-29;9(9):7. Unique Identifier : AIDSLINE MED/95110736; Leifer D
Outcomes of intensive AIDS education for male adolescent drug users in jail.: J Adolesc Health. 1994 Sep;15(6):457-63. Unique Identifier : AIDSLINE MED/95110793; Magura S; Kang SY; Shapiro JL; Institute for Treatment and Services Research, National; Development and Research Institutes, Inc., New York, NY 10013.; OBJECTIVES: The purpose of the study was to conduct and evaluate an intensive AIDS education program for incarcerated male adolescent drug users. METHODS: The study was conducted in New York City s main jail facility for detained and sentenced male youths aged 16-19 years. A four-session, group-oriented AIDS education
Characteristics of teens tested for HIV in a metropolitan area.: J Adolesc Health. 1994 Sep;15(6):479-84. Unique Identifier : AIDSLINE MED/95110796; Ilegbodu AE; Frank ML; Poindexter AN; Johnson D; Department of Obstetrics and Gynecology, Baylor College of; Medicine, Houston, TX 77030.; PURPOSE: This article describes the status of HIV infection in an adolescent population attending publicly supported HIV testing clinics in Houston. METHODS: Records were reviewed of 4017 teenagers receiving HIV counseling and testing services over a period of three years (January 1990 to December 1992). We analyzed d
Determinants of condom use by Australian secondary school students.: J Adolesc Health. 1994 Sep;15(6):503-10. Unique Identifier : AIDSLINE MED/95110800; Donald M; Lucke J; Dunne M; O'Toole B; Raphael B; National Centre for HIV Social Research, University of; Queensland, Australia.; PURPOSE: To identify factors that are associated with condom use to aid in the understanding of how to change the behavior of those young people who have sex without using condoms. METHODS: The article reports data from 932 sexually active grade 10-12 students from a sample of 72 public secondary schools in seven Aust
[Clinicoepidemiologic study of tuberculosis in the Ferrol area (1990-1991)]: Enferm Infecc Microbiol Clin. 1994 Nov;12(9):443-8. Unique Identifier : AIDSLINE MED/95110888; Sesma P; Diaz-Miguez MD; Deben M; Garcia-Rodriguez JF; Grandes J; Rodriguez-Mayo MD; Servicio de Medicina Interna, Hospital Arquitecto Marcide,; Ferrol.; BACKGROUND: To know about the main characteristics of tuberculous disease in our county. METHOD: A two-year period (1990-91), retrospective survey of the patients diagnosed of tuberculosis at a hospital from the north of La Coruna ( Spain ) was performed. A total of 322 cases were fou
[Pneumothorax in patients with AIDS]: Enferm Infecc Microbiol Clin. 1994 Nov;12(9):452-4. Unique Identifier : AIDSLINE MED/95110890; Rivero A; Lopez T; Santos J; Marquez M; Avisbal N; Gonzalez-Santos P; Unidad de Enfermedades Infecciosas (Servicio de Medicina Interna,; Hospital Universitario Virgen de la Victoria, Malaga.; METHODS: From January 1986 to 31 November 1993, 354 cases of AIDS (CDC criteria 1987) were diagnosed. The possible existence of spontaneous pneumothorax at any time during the evolution and its presumed cause were evaluated. RESULTS: During the period studied, 7 (1.9%) of AIDS patients presented pneumothorax. The exis
[The AIDS patient of the 90s (II)]: Enferm Infecc Microbiol Clin. 1994 Nov;12(9):455-64. Unique Identifier : AIDSLINE MED/95110891; Iribarren JA; Arrizabalaga J; Rodriguez Arrondo F; von Wichmann MA; Oyarbide J; Huarte I; Unidad de Enfermedades Infecciosas, Hospital Nuestra Senora de; Aranzazu, San Sebastian S.
[Skin nodules and epigastric pain in a patient with HIV infection]: Enferm Infecc Microbiol Clin. 1994 Nov;12(9):465-7. Unique Identifier : AIDSLINE MED/95110892; Cabrerizo JF; Perez-Cortes S; Sanchez-Angulo JI; Silva A; Unidad de Enfermedades Infecciosas, Hospital General del S.A.S.,; Jerez de la Frontera, Cadiz.
[Rhodococcus equi pneumonia in a patient with AIDS. Primary resistance to imipenem (letter)]: Enferm Infecc Microbiol Clin. 1994 Nov;12(9):471-2. Unique Identifier : AIDSLINE MED/95110897; Fernandez A; Santos J; Sanchez MA; Alfaro C
[HIV-2 AIDS in Guipuzcoa (letter)]: Enferm Infecc Microbiol Clin. 1994 Nov;12(9):473-5. Unique Identifier : AIDSLINE MED/95110900; Cilla G; Perez-Trallero E; Palacio L; Senosiain JM; de la Puente E
Routine analysis of induced sputum is not an effective strategy for screening persons infected with human immunodeficiency virus for Mycobacterium tuberculosis or Pneumocystis carinii. Pulmonary Complications of HIV Infection Study Group.: Clin Infect Dis. 1994 Sep;19(3):410-6. Unique Identifier : AIDSLINE MED/95110980; Kvale PA; Hansen NI; Markowitz N; Rosen MJ; Jordan MC; Meiselman L; Glassroth J; Reichman LB; Wallace JM; Stansell JD; et al; Henry Ford Hospital, Division of Pulmonary and Critical Care; Medicine, Detroit, Michigan 48202.; A prospective multicenter cohort study comprising 1,171 individuals who were seropositive for human immunodeficiency virus (HIV) but did not have AIDS at the time of enrollment and 182 HIV-seronegative controls, was studied by means of routine induced-sputum analysis in an attempt to detect occult tuberculosis or Pneu
Serious Pseudomonas aeruginosa infections in patients infected with human immunodeficiency virus: a case-control study.: Clin Infect Dis. 1994 Sep;19(3):417-22. Unique Identifier : AIDSLINE MED/95110981; Fichtenbaum CJ; Woeltje KF; Powderly WG; Department of Internal Medicine, Washington University School of; Medicine, St. Louis, Missouri 63110.; We conducted a case-control study to determine the incidence and clinical features of and risk factors for Pseudomonas aeruginosa infections in patients infected with human immunodeficiency virus (HIV). Twenty-five patients who had 37 episodes of P. aeruginosa infection from 1990 through 1992 were identified. Most of
Trimethoprim-induced aseptic meningitis in a patient with AIDS: case report and review.: Clin Infect Dis. 1994 Sep;19(3):431-4. Unique Identifier : AIDSLINE MED/95110983; Harrison MS; Simonte SJ; Kauffman CA; Department of Internal Medicine, University of Michigan Medical; School, Ann Arbor.; We report the case of a 41-year-old man infected with human immunodeficiency virus who had two episodes of aseptic meningitis that occurred 2 weeks apart; the first was associated with ingestion of trimethoprim-sulfamethoxazole (TMP-SMZ) and the second was associated with ingestion of TMP alone. Onset of fever, headac
Sexual behavior and perceived risk of AIDS among men in Kenya attending a clinic for sexually transmitted diseases.: Clin Infect Dis. 1994 Sep;19(3):441-7. Unique Identifier : AIDSLINE MED/95110985; Tyndall MW; Agoki E; Malisa W; Ndinya-Achola JO; Ronald AR; Plummer FA; Department of Medical Microbiology, University of Nairobi, Kenya.; The sexual transmission of human immunodeficiency virus type 1 (HIV-1) continues at an alarming rate in sub-Saharan Africa despite the fact that awareness of AIDS is high. One explanation for this alarming rate may be that individuals do not believe that they are personally at risk for AIDS and are not sufficiently mo
Severe measles pneumonitis in adults: evaluation of clinical characteristics and therapy with intravenous ribavirin [see comments]: Clin Infect Dis. 1994 Sep;19(3):454-62. Unique Identifier : AIDSLINE MED/95110987; Forni AL; Schluger NW; Roberts RB; Department of Medicine, Cornell University Medical College, New; York, New York 10021.; Between February and April 1991, six adults were admitted to the New York Hospital because of measles pneumonitis. The diagnosis was confirmed by serology and/or viral culture. Uncommon clinical features among patients with this diagnosis included thrombocytopenia, hepatitis, myositis, and hypocalcemia. All patients w
Pilot study of azithromycin for treatment of primary and secondary syphilis.: Clin Infect Dis. 1994 Sep;19(3):486-8. Unique Identifier : AIDSLINE MED/95110990; Verdon MS; Handsfield HH; Johnson RB; Seattle-King County Department of Public Health, Washington.; Azithromycin has in vitro activity against Treponema pallidum and is effective against experimental syphilis in rabbits. We undertook an open, noncomparative pilot study of oral azithromycin (500 mg once daily for 10 days) to treat 16 patients with primary or secondary syphilis who were seronegative for human immunode
Antibody-dependent enhancement of infection and the pathogenesis of viral disease.: Clin Infect Dis. 1994 Sep;19(3):500-12. Unique Identifier : AIDSLINE MED/95110992; Morens DM; Department of Tropical Medicine, University of Hawaii School of; Medicine, Honolulu.; Antibody-dependent enhancement of infection (ADE) is an in vitro serological phenomenon--or a group of phenomena--in which viral infection of susceptible cells is modified by the addition of virus-reactive antibody. Evidence suggests that ADE reflects immunologic processes that occur in vivo. Various severe and even f
Enterocytozoon bieneusi infection in an immunocompetent patient who had acute diarrhea and who was not infected with the human immunodeficiency virus.: Clin Infect Dis. 1994 Sep;19(3):514-6. Unique Identifier : AIDSLINE MED/95110993; Sandfort J; Hannemann A; Gelderblom H; Stark K; Owen RL; Ruf B; Department of Infectious Diseases, Rudolf Virchow University; Hospital, Freie Universitat Berlin, Germany.; Enterocytozoon bieneusi is a microsporidian species that has been detected exclusively in patients infected with human immunodeficiency virus (HIV) who are severely immunocompromised. We report what we believe is the first case of E. bieneusi infection in an HIV-negative patient with acute, self-limited diarrhea whose
Microsporidial infections in immunodeficient and immunocompetent patients.: Clin Infect Dis. 1994 Sep;19(3):517-21. Unique Identifier : AIDSLINE MED/95110994; Weber R; Bryan RT; Department of Medicine, University Hospital, Zurich, Switzerland.; Microsporidia are obligate, intracellular, spore-forming protozoal parasites. Their host range is extensive and includes most invertebrates and all classes of vertebrates. Five microsporidial genera (Enterocytozoon, Encephalitozoon, Septata, Pleistophora, and Nosema) and unclassified microsporidia have been associated
Fungemia due to fluconazole-resistant Candida albicans in a patient with AIDS [letter]: Clin Infect Dis. 1994 Sep;19(3):542-3. Unique Identifier : AIDSLINE MED/95110998; Laguna F; Rodriguez-Tudela JL; Enriquez A
Transmission of hepatitis C virus but not human immunodeficiency virus type 1 by a human bite [letter]: Clin Infect Dis. 1994 Sep;19(3):546-7. Unique Identifier : AIDSLINE MED/95111001; Figueiredo JF; Borges AS; Martinez R; Martinelli A de L; Villanova MG; Covas DT; Passas AD
Prolonged concurrent use of ganciclovir and foscarnet in the treatment of polyradiculopathy due to cytomegalovirus in a patient with AIDS [letter]: Clin Infect Dis. 1994 Sep;19(3):548-9. Unique Identifier : AIDSLINE MED/95111003; Decker CF; Tarver JH 3rd; Murray DF; Martin GJ
Hypophyseal tuberculosis in a patient with AIDS [letter]: Clin Infect Dis. 1994 Sep;19(3):550-1. Unique Identifier : AIDSLINE MED/95111005; Eyer-Silva WA; Morais de Sa CA; de Oliveira CA; Pinto JF; Vaz LF; Gameiro CA
Polymicrobial pyomyositis and bacteremia in a patient with AIDS [letter]: Clin Infect Dis. 1994 Sep;19(3):552-3. Unique Identifier : AIDSLINE MED/95111007; Lortholary O; Jehl F; Petitjean O; Cohen P; Tarral E; Guillevin L
Pulmonary abscess due to non-typhi Salmonella in a patient with AIDS [letter]: Clin Infect Dis. 1994 Sep;19(3):555-7. Unique Identifier : AIDSLINE MED/95111010; Satue JA; Aguado JM; Ramon Costa J; Robledo M; De Miguel E; Hernandez J; Rioperez E
Relapse of visceral leishmaniasis in patients who were coinfected with human immunodeficiency virus and who received treatment with liposomal amphotericin B [letter; comment] [see comments]: Clin Infect Dis. 1994 Sep;19(3):560. Unique Identifier : AIDSLINE MED/95111014; Davidson RN; Russo R
Hospital care grievances and psychosocial needs expressed by PWAs: an analysis of qualitative data.: J Assoc Nurses AIDS Care. 1994 Sep-Oct;5(5):21-9. Unique Identifier : AIDSLINE MED/95111108; Foley ME; Fahs MC; Department of Community Medicine, Mount Sinai School of Medicine,; New York, NY.; Despite the growing number of HIV-related hospital admissions, reports of hospitalization experiences of persons with AIDS has been sparse. As part of a larger quantitative study to assess how arrangements of care of patients with AIDS are related to quality of care, the authors analyzed qualitative data collected dur
The content of ethical problems experienced by persons with AIDS.: J Assoc Nurses AIDS Care. 1994 Sep-Oct;5(5):32-42. Unique Identifier : AIDSLINE MED/95111109; Cameron ME; Crisham P; Lewis DE; School of Nursing, University of Minnesota, Minneapolis.; The purpose of this research was to describe and examine the basic nature (essences) and content (subject-matter) of ethical problems involving AIDS that are experienced by persons with AIDS (PWAs). The participants were 25 PWAs and 5 significant others, the latter included to provide contextual understanding. During
Infections related to venous access devices in patients with AIDS.: J Assoc Nurses AIDS Care. 1994 Sep-Oct;5(5):43-7. Unique Identifier : AIDSLINE MED/95111110; Settle JT; Neff-Smith M; Wan GJ; AIDS Program, Medical College of Virginia Hospitals, Richmond.; The use of implanted venous access devices (VADs) for long-term administration of medications and fluids in HIV/AIDS patients has become common. This retrospective study compared infection rates in implanted external catheters and totally implanted ports. The study also investigated possible relationships between infe
Evaluating interventions for fear of contagion.: J Assoc Nurses AIDS Care. 1994 Sep-Oct;5(5):48-55. Unique Identifier : AIDSLINE MED/95111111; Meisenhelder JB; Rice L; Center for Nursing Research, New England Deaconess Hosptial,; Boston, MA.; Fear of contagion, an anxious response to the perceived threat of catching HIV, has been shown to lessen with contact with persons with AIDS. Two different continuing educational offerings presented a panel of persons living with HIV as an intervention to decrease fear of contagion. Presession and postsession question
Bone marrow transplantation in major histocompatibility complex class II deficiency: a single-center study of 19 patients.: Blood. 1995 Jan 15;85(2):580-7. Unique Identifier : AIDSLINE MED/95111145; Klein C; Cavazzana-Calvo M; Le Deist F; Jabado N; Benkerrou M; Blanche S; Lisowska-Grospierre B; Griscelli C; Fischer A; Unite d'Immunologie et d'Hematologie, Hopital Necker Enfants; Malades, Paris, France.; Major histocompatibility complex (MHC) class II deficiency (bare lymphocyte syndrome) is a rare inborn error of the immune system characterized by impaired antigen presentation and combined immunodeficiency. It causes severe and unremitting infections leading to progressive liver and lung dysfunctions and death during
Kaposi's sarcoma and AIDS in Uganda: its frequency and gastrointestinal distribution.: Ital J Gastroenterol. 1994 Sep;26(7):329-33. Unique Identifier : AIDSLINE MED/95111157; Ravera M; Reggiori A; Cocozza E; Andreata M; Ciantia F; Hoima Hospital, Italian Cooperation, Kampala, Uganda.; The frequency and distribution of gastrointestinal Kaposi s sarcoma were investigated in 63 consecutive AIDS patients. The main risk factor for AIDS was heterosexual intercourse. Gastrointestinal lesions were found in 24 cases (38.1%): 12 patients (11.1%) had both upper and lower GI tract involvement, 7 patients (11.1
[HIV-1 and tears. Results of virus isolation and polymerase chain reaction (PCR)]: Ophthalmologe. 1994 Oct;91(5):663-7. Unique Identifier : AIDSLINE MED/95111242; Mueller AJ; Geier S; Gurtler L; Klauss V; Augenklinik, Universitat Munchen.; Beside the threat of infection via HIV-containing blood, the ophthalmologist is especially interested in the possibility of HIV infection via the tears of HIV-positive persons. In a first step, we tried to isolate HIV-1 from the peripheral blood lymphocytes (PBL) of 50 HIV-1-antibody-positive persons in different stag
[Ophthalmologic manifestations in early and late stages of AIDS]: Ophthalmologe. 1994 Oct;91(5):668-70. Unique Identifier : AIDSLINE MED/95111243; Schnaudigel OE; Gumbel H; Richter R; Subklew R; Garweg T; Zentrum der Augenheilkunde, Universitat Frankfurt/M.; In a prospective study of 101 patients with HIV infection and a medium CD4 lymphocyte cell count of 350 x 10(6)/l and a retrospective study of the records of 79 AIDS patients, we compared the first ocular symptoms in HIV-infected patients to the CD4 count. In Walter-Reed stages 2-4 (n = 101) we found sicca syndrome in
[No detection of mycoplasma in 205 conjunctival swabs]: Ophthalmologe. 1994 Oct;91(5):676-9. Unique Identifier : AIDSLINE MED/95111245; Grasbon T; Mino de Kaspar H; Klauss V; Augenklinik der Universitat Munchen.; Mycoplasma is known to cause pulmonary and urogenital infections in humans. A pathogenicity for the human eye never has been assessed, although they have been observed in the peripheral eye in a few cases of acute and non-specific conjunctivitis, in patients with Reiter s disease and in newborns. Due to the absence of
[Laser therapy of eyelid and conjunctival tumors, especially in AIDS patients]: Ophthalmologe. 1994 Oct;91(5):691-3. Unique Identifier : AIDSLINE MED/95111248; Rodenbach M; Gumbel H; Makabe R; Abteilung fur Funktionsdiagnostik und Lasertherapie; Universitats-Augenklinik Frankfurt.; We treated patients with Kaposi s sarcoma of the lid or conjunctiva, molluscum contagiosum and papilloma of the lid with dye laser photocoagulation. This therapeutic device is extremely efficient as the chosen wavelength of 577 nm is absorbed selectively by haemoglobin. Since Kaposi s sarcoma is a haemoglobin-containi
Trichomonas vaginalis: repeated DNA target for highly sensitive and specific polymerase chain reaction diagnosis.: Cell Mol Biol (Noisy-le-grand). 1994 Sep;40(6):819-31. Unique Identifier : AIDSLINE GENBANK/L23861; Kengne P; Veas F; Vidal N; Rey JL; Cuny G; Laboratoire Retrovirus-Parasites, Institut Francais de; Recherche Scientifique pour le Developpement en Cooperation; (ORSTOM), Montpellier, France.; Trichomoniasis is recognised as a major sexually transmitted disease (STD) in the world and may act as an acquired immunodeficiency syndromes (AIDS) co-factor by enhancing the transmission of human immunodeficiency virus (HIV). Diagnosis of Trichomonas vaginalis can be achieved by several methods, but sensitive detect
Hypercalcemia, parathyroid hormone-related protein expression and human T-cell leukemia virus infection.: Leuk Lymphoma. 1994 Aug;14(5-6):395-400. Unique Identifier : AIDSLINE MED/95111349; Prager D; Rosenblatt JD; Ejima E; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles,; California 90048.; Adult T-cell leukemia (ATL) associated with HTLV-1 infection is characterized by the development of hypercalcemia in over two thirds of patients. Dysregulation of cellular gene transcription by viral proteins is an emerging paradigm for molecular pathogenesis of disease. A recent example is the parathyroid hormone-rel
A patient with primary hypoparathyroidism developing hypercalcemia associated with adult T-cell leukemia/lymphoma.: Leuk Lymphoma. 1994 Aug;14(5-6):521-5. Unique Identifier : AIDSLINE MED/95111368; Kondo S; Tamura K; Makino S; Yokota T; Ishikawa E; Katakami H; Kohari S; Department of Internal Medicine, Miyazaki Prefectural Hospital,; Japan.; A 38-year-old woman was admitted to our hospital with symptoms and signs of hypocalcemia in 1977 and a diagnosis of primary hypoparathyroidism was made with a positive Ellsworth Howard test. She was then lost to follow up until 1992 when she returned this time with symptoms and signs of hypercalcemia. An inguinal lymp
Committee to Advise on Tropical Medicine and Travel (CATMAT). Statement on travellers and HIV/AIDS.: Can Commun Dis Rep. 1994 Sep 15;20(17):147-9. Unique Identifier : AIDSLINE MED/95111386
Detection of serum antibodies in tuberculosis patients.: Cent Eur J Public Health. 1994 Jun;2(1):60-1. Unique Identifier : AIDSLINE MED/95111406; Jarosikova T; Sow OY; Traore S; Krest'anpol M; Kubin M; Bruckova M; Department of Mycobacterial Diseases, National Institute of; Public Health, Prague, Czech Republic.; Sera of 14 bacteriological confirmed pulmonary tuberculosis and 16 non-tuberculotic or healthy controls were sampled in Ignace Deen University Hospital in Conakry, Quinea. Samples were examined for IgG and IgM antibodies by means of enzyme-linked immunosorbent assay (ELISA) using sonicated M. bovis BCG and M. avium an
Human resource needs, health care reform, and the practice of medicine/psychiatry.: Bull Menninger Clin. 1994 Fall;58(4):454-61. Unique Identifier : AIDSLINE MED/95111412; Arons BS; Georgetown University School of Medicine.; Health care reform, which is anticipated at the federal level and is ongoing at the state level, presents both challenges and opportunities for psychiatrists and other mental health practitioners. It is important that all the mental health professions examine their training programs in preparation for the changes that
Interaction of virulent and non-virulent Rhodococcus equi human isolates with phagocytes, fibroblast- and epithelial-derived cells.: FEMS Immunol Med Microbiol. 1994 Sep;9(3):199-205. Unique Identifier : AIDSLINE MED/95111429; Nordmann P; Zinzendorf N; Keller M; Lair I; Ronco E; Guenounou M; Laboratoire de Microbiologie, Hopital Raymond Poincare,; Faculte de Medecine Paris-Ouest, Universite Paris 5, Garches,; France.; Rhodococcus equi is a facultative, intracellular, Gram-positive coccobacillus, increasingly reported in pneumonia of AIDS-infected patients. We investigated killing resistance properties of human R. equi virulent and avirulent human strains. Avirulent beta-lactam-susceptible strains had lower intracellular colony form
[Does septic arthritis occur in human immunodeficiency virus infection?]: Rev Rhum Ed Fr. 1994 May;61(5):343-7. Unique Identifier : AIDSLINE MED/95111452; Saraux A; Blanche P; Taelman H; Batungwanayo J; van de Perre P; Le Goff P; Bogaerts J; Service de Rhumatologie, Hopital Morvan, Brest.; No prospective, longitudinal, cohort studies comparing septic arthritis in HIV-positive and HIV-negative individuals belonging to the various risk factor groups for HIV-infection are available. However, a review of the literature provided information on the main features of pyarthrosis in HIV-infected patients. The cl
Preventing 'needlesticks'.: Nurs N Z. 1994 Nov;2(10):29. Unique Identifier : AIDSLINE MED/95111494; Berkett L; O'Brien L
Methods in the Virtual Wetlab I: rule-based reasoning driven by nearest-neighbor lattice dynamics.: Artif Intell Med. 1994 Aug;6(4):301-19. Unique Identifier : AIDSLINE MED/95111598; Sieburg HB; Laboratory for Biological Informatics & Theoretical Medicine,; University of California, San Diego, La Jolla 92093-0603.; We describe a discrete dynamical systems approach to exploring the hypothesis-trees associated with wetlab experiments. On-going applications of the method to experimental research using a genetically engineered mouse animal model with severe combined immune deficiency (SCID) in the area of HIV infection are outlined
[Anti-HIV antibody screening kits and the difficulties of serology. Retrovirus Working Group of the Societe Francaise de la Transfusion Sanguine]: Transfus Clin Biol. 1994;1(5):387-95. Unique Identifier : AIDSLINE MED/95111648; Courouce AM; The combined HIV1 + HIV2 assays allow to screen simultaneously the subjects infected by HIV1 or by HIV2 (About 80 HIV1 for 1 HIV2 in blood donations in France ). An improvement of both sensitivity and specificity was obtained by using artificial proteins which have been selected for
Frequency of human immunodeficiency virus testing among rural US residents and why it is done.: Arch Fam Med. 1995 Jan;4(1):41-5. Unique Identifier : AIDSLINE MED/95111659; Mainous AG 3rd; Neill RA; Matheny SC; Department of Family Practice, University of Kentucky, Lexington.; OBJECTIVE: To examine the frequency with which rural residents undergo human immunodeficiency virus (HIV) antibody testing and the reasons why. DESIGN: Data are from the 1991 National Health Interview Survey s supplemental questions on knowledge and attitudes about acquired immunodeficiency syndrome. SUBJECTS: The re
Dexamethasone for intractable hiccoughs in a patient with AIDS and PML [letter]: Palliat Med. 1994 Oct;8(4):337-8. Unique Identifier : AIDSLINE MED/95111675; McKeogh M
Expression of human T-cell leukaemia virus type I and associated antigens, and interleukin-2 and receptor in lymph nodes of adult T-cell leukaemia/lymphoma.: Virchows Arch. 1994;425(3):249-58. Unique Identifier : AIDSLINE MED/95111701; Ohshima K; Kikuchi M; Kobari S; Shiraki H; Sumiyoshi Y; Yoneda S; Masuda Y; Takeshita M; Kimura N; Department of Pathology, School of Medicine, Fukuoka University,; Japan.; To examine the relationship between the expression of human T-cell leukaemia virus type (HTLV-I) mRNA and associated antigens and clinicopathological features, we studied 31 lymph nodes of patients with adult T-cell leukaemia/lymphoma (ATLL) and related diseases, using in situ hybridization and immunohistochemistry. W
Detection of Epstein Barr virus in an hepatic leiomyomatous neoplasm in an adult human immunodeficiency virus 1-infected patient.: Virchows Arch. 1994;425(3):321-5. Unique Identifier : AIDSLINE MED/95111710; Prevot S; Neris J; de Saint Maur PP; Department of Pathology, Saint-Antoine Hospital, Paris, France.; We report the first case of a human immunodeficiency virus (HIV)-related primary hepatic leiomyoma in an adult patient. The diagnosis was made at autopsy and confirmed by immunohistochemistry. Epstein Barr virus (EBV) was identified in tumour cells by in situ hybridization. Review of the literature revealed 13 cases o
[Ethics and public health]: Soins Form Pedagog Encadr. 1993 TRIMESTER 4;(8):3-9. Unique Identifier : AIDSLINE MED/95111718; Lery N; Lery L
Accelerated course of human immunodeficiency virus infection after tuberculosis.: Am J Respir Crit Care Med. 1995 Jan;151(1):129-35. Unique Identifier : AIDSLINE MED/95111733; Whalen C; Horsburgh CR; Hom D; Lahart C; Simberkoff M; Ellner J; Department of Medicine, Cleveland Veterans Affairs Medical; Center, Ohio.; To determine the effect of active tuberculosis on survival and the incidence of opportunistic infections in HIV-infected patients, we performed a retrospective cohort study at four U.S. medical centers to compare the survival and incidence rate of opportunistic infections in 106 HIV-infected patients with active tuber
Proinflammatory cytokines in hypersensitivity pneumonitis.: Am J Respir Crit Care Med. 1995 Jan;151(1):164-9. Unique Identifier : AIDSLINE MED/95111739; Denis M; Pulmonary Research Unit, Faculty of Medicine, University of; Sherbrooke, Quebec, Canada.; We examined the synthesis and release of the proinflammatory cytokines macrophage inflammatory protein-1 alpha (MIP-1 alpha) and interleukin-8 (IL-8) in the context of subjects with hypersensitivity pneumonitis (HP). Subjects with acute HP were found to have alveolar macrophages that released high levels of MIP-1 alph
Increased Pneumocystis carinii recovery from upper lobes in Pneumocystis pneumonia [letter; comment]: Am J Respir Crit Care Med. 1995 Jan;151(1):253-4. Unique Identifier : AIDSLINE MED/95111756; Baughman RB; Dohn MN
Infection by HIV-1 blocked by binding of dextrin 2-sulphate to the cell surface of activated human peripheral blood mononuclear cells and cultured T-cells.: Br J Pharmacol. 1994 Sep;113(1):151-8. Unique Identifier : AIDSLINE MED/95111798; Shaunak S; Gooderham NJ; Edwards RJ; Payvandi N; Javan CM; Baggett N; MacDermot J; Weber JN; Davies DS; Department of Infectious Diseases, Royal Postgraduate Medical; School, London.; 1. Structural analogues of a sulphated polysaccharide, dextrin sulphate, were synthesized and tested for their ability to block infection by HIV-1. Using the T-cell lines, C8166 and HPB-ALL, and the laboratory adapted strains of HIV-1.MN, HIV-1.IIIb and HIV-1.RF, dextrin 2-sulphate (D2S) combined the best combination
Infectious esophagitis.: Gastrointest Endosc Clin N Am. 1994 Oct;4(4):713-29. Unique Identifier : AIDSLINE MED/95111844; Sutton FM; Graham DY; Goodgame RW; Baylor College of Medicine, Houston, Texas.; This article presents the epidemiology, pathogenesis and pathology, clinical manifestations, and diagnosis and treatment of Candida, herpes simplex virus, cytomegalovirus , Mycobacterium tuberculosis, Aspergillus, histoplasmosis, blastomycosis, and HIV. Uncommon AIDS-related esophag
Benign and malignant esophageal tumors other than squamous and adenocarcinoma.: Gastrointest Endosc Clin N Am. 1994 Oct;4(4):791-801. Unique Identifier : AIDSLINE MED/95111848; Fockens P; Bartelsman JF; Tytgat GN; Academic Medical Center, Amsterdam, The Netherlands.; The spectrum of esophageal tumors is diverse, although most tumors are squamous and adenocarcinoma. In this article the benign esophageal tumors are discussed as well as the uncommon malignant tumors, including the metastatic ones. Endoscopic pictures of most of these tumors are presented.
RNA-sequence-mediated gene regulation in HIV-1.: Infect Agents Dis. 1994 Apr-Jun;3(2-3):68-76. Unique Identifier : AIDSLINE MED/95111891; Cullen BR; Howard Hughes Medical Institute, Duke University Medical Center,; Durham, North Carolina 27710.; The quantity and quality of human immunodeficiency virus type 1 (HIV-1) gene expression is controlled in large part by the action of two small nuclear viral regulatory proteins termed Tat and Rev. Tat is unique among transcriptional trans-activators in that it acts via a structured RNA target sequence, termed TAR, to
Role of bacteria-specific T cells in the immunopathogenesis of reactive arthritis.: Trends Microbiol. 1994 Sep;2(9):329-32. Unique Identifier : AIDSLINE MED/95111902; Probst P; Hermann E; Fleischer B; Bernhard-Nocht Institute for Tropical Medicine, Germany.; Reactive arthritis is a usually self-limited sterile inflammation of joints that follows certain bacterial gastrointestinal or urogenital infections. The immunopathogenesis involves CD4+ T cells, which mediate an antigen-specific TH1 response to bacterial constituents within the joint. Properties of the arthritogenic
A retroviral implication in multiple sclerosis?: Trends Microbiol. 1994 Sep;2(9):332-6. Unique Identifier : AIDSLINE MED/95111903; Christensen T; Moller-Larsen A; Haahr S; Institute of Medical Microbiology, University of Aarhus, Denmark.; The etiology of multiple sclerosis (MS) is still unexplained. Epidemiological studies indicate that environmental agents are involved, and MS shares both clinical and histopathological features with retrovirus-mediated neurological diseases in animals and humans. Thus, combining the fields of microbiology and epidemio
[Residual infectious risk of blood transfusion]: Cah Anesthesiol. 1994;42(3):357-60. Unique Identifier : AIDSLINE MED/95112179; Janot C; Botte C; Centre Regional de Transfusion Sanguine, Vandoeuvre-les-Nancy.
IL-4: a key cytokine in atopy.: Clin Exp Allergy. 1994 Sep;24(9):801-12. Unique Identifier : AIDSLINE MED/95112199; Ricci M; Istituto Clinica Medica III, University of Florence, Italy.
Dermatophagoides pteronyssinus II-induced interleukin-4 and interferon-gamma expression by freshly isolated lymphocytes of atopic individuals.: Clin Exp Allergy. 1994 Sep;24(9):878-83. Unique Identifier : AIDSLINE MED/95112206; Byron KA; O'Brien RM; Varigos GA; Wootton AM; Department of Biochemistry, Royal Melbourne Hospital, Victoria,; Australia.; Cytokines are known to play a major role in mediating many of the immunological and pathological features of allergic disease. Much of our understanding of cytokine production in response to allergens has come from studying allergen-specific T cell clones following long-term in vitro culture. This has largely been due
Human T-lymphotropic virus type-I influence on hepatotropic virus infections and the subsequent development of hepatocellular carcinoma.: Cancer Detect Prev. 1994;18(5):329-34. Unique Identifier : AIDSLINE MED/95112308; Kamihira S; Yamada Y; Sohda H; Atogami S; Tomonaga M; Egawa S; Fujii M; Chifu K; Blood Transfusion Service, School of Medicine, Nagasaki; University, Japan.; We studied the serologic status, with respect to hepatitis B virus (HBV), hepatitis C virus (HCV), and human T-lymphotropic virus type-I (HTLV-I) of blood donors in an area endemic for adult T-cell leukemia (ATL). Similarly, we studied the serologic status of hepatocellular carcinoma (HCC) patients from the same distr
Multistep alterations of human lymphocytes infected with HTLV-I and then exposed to carcinogens.: Cancer Detect Prev. 1994;18(5):335-42. Unique Identifier : AIDSLINE MED/95112309; Mochizuki S; Fukushima T; Maruyama K; Department of Pathology, Chiba Cancer Center Research Institute,; Japan.; Normal human lymphocytes achieved continuous growth in IL-2-containing medium in vitro following HTLV-I infection. They showed specific structural abnormalities of certain chromosomes. Subsequent to exposure to MNNG and TPA, or to UV, they achieved autonomous growth (transformation). Alterations in the signal transduc
Lung cancer in the young.: Cancer Detect Prev. 1994;18(5):349-55. Unique Identifier : AIDSLINE MED/95112311; Rocha MP; Fraire AE; Guntupalli KK; Greenberg SD; Department of Pulmonary Medicine, Baylor College of Medicine,; Houston, TX.; Lung cancer is uncommon in individuals age 40 or less. We reviewed the Cancer Registry files of the Ben Taub General Hospital (Houston, TX) from 1971 to 1989 and identified 1678 patients with a documented diagnosis of lung cancer. Among these 1678 patients, 50 (2.98%) were age 40 or less. Thirty-five (70%) of the 50 p
Hypothyroxinemia in acquired immune deficiency syndrome (AIDS).: Cent Afr J Med. 1994 Aug;40(8):226-9. Unique Identifier : AIDSLINE MED/95112333; Ezeala CC; Chukwurah E; Department of Radiation Medicine, University of Nigeria Teaching; Hospital, Enugu.; Serum thyroxine (T4) and thyroid stimulating hormone (TSH) were studied in 38 patients confirmed to be infected with HIV-1 virus and the results compared with values observed in age matched healthy subjects. The mean serum total T4 in the majority of the patients, 103 +/- 32 nmol/L, was similar to values observed in t
A prospective controlled crossover trial of a new heat-treated intravenous immunoglobulin.: Clin Exp Immunol. 1995 Jan;99(1):10-5. Unique Identifier : AIDSLINE MED/95112439; Zuhrie SR; Webster AD; Davies R; Fay AC; Wallington TB; Immunodeficiency Research Group, Clinical Research Centre,; Harrow, UK.; Twenty-one patients with primary immunoglobulin deficiency were enrolled in a crossover study to test the efficacy and safety of Alphaglobin in comparison with the licensed preparations Sandoglobulin and Gamimune. There was no statistical difference in these parameters between Alphaglobin and Sandoglobulin/Gamimune. T
Failure of IgG production due to a defect in the opening of the chromatin structure of I gamma 1 region in a patient with IgG and IgA deficiency.: Clin Exp Immunol. 1995 Jan;99(1):21-8. Unique Identifier : AIDSLINE MED/95112447; Kondo N; Inoue R; Kasahara K; Kaneko H; Kameyama T; Orii T; Department of Paediatrics, Gifu University School of Medicine,; Japan.; Patients with common variable immunodeficiency (CVID) display reduced levels of two or all three of the major immunoglobulin isotypes, and the deficiency is characterized by failure of B cells to differentiate into plasma cells in many cases. A patient (14 years old, female) showed normal serum IgM levels and low seru
Interferon-gamma (IFN-gamma) production by human T lymphocytes upon Legionella pneumophila stimulation in vitro.: Clin Exp Immunol. 1995 Jan;99(1):76-81. Unique Identifier : AIDSLINE MED/95112456; Kitsukawa K; Nakamoto A; Koito H; Matsuda Y; Saito A; Yamamoto H; Department of Immunology, National Institute of Neuroscience,; NCNP, Tokyo, Japan.; In vitro immune responses to Legionella pneumophila were investigated. When human peripheral blood lymphocytes (PBL) from healthy volunteers were stimulated with formalin-killed L. pneumophila for 7 days in vitro, strong proliferative responses were observed. The responding cells were shown to be a CD4 T cell subset.
Multifocal M. intracellulare osteomyelitis in an immunocompetent child.: Clin Pediatr (Phila). 1994 Oct;33(10):611-6. Unique Identifier : AIDSLINE MED/95112485; Raszka WV Jr; Trinh TT; Zawadsky PM; Department of Pediatrics, William Beaumont Army Medical Center,; El Paso, Texas 79920.; We report the successful treatment of disseminated Mycobacterium intracellulare osteomyelitis, without evidence of other visceral involvement, in a previously healthy, HIV-negative, 2-year-old female using a 23-month regimen of antimicrobial agents that included 18 months of oral therapy with azithromycin, rifabutin,
Human immunodeficiency virus (HIV) infection as a leading cause of death among young adults aged 25 to 44 years in Connecticut.: Conn Med. 1994 Nov;58(11):661-3. Unique Identifier : AIDSLINE MED/95112556; Checko PJ; AIDS Division, Connecticut Department of Public Health and; Addiction Services, Hartford 06106.
AIDS in Connecticut, annual surveillance report--executive summary.: Conn Med. 1994 Nov;58(11):665-6. Unique Identifier : AIDSLINE MED/95112557; Checko PJ; AIDS Division, Connecticut Department of Public Health and; Addiction Services, Hartford 06106.
Transbronchial biopsy in the diagnosis of pulmonary infiltrates in immunocompromised patients.: Chest. 1995 Jan;107(1):101-6. Unique Identifier : AIDSLINE MED/95112603; Cazzadori A; Di Perri G; Todeschini G; Luzzati R; Boschiero L; Perona G; Concia E; Endoscopy Unit, University of Verona, Italy.; Bronchoalveolar lavage (BAL) and transbronchial biopsy (TBB) frequently are performed in the investigation of immunocompromised patients with lung disorders. The risk-benefit ratio of TBB currently is debated, since several authors have found that the less invasive BAL may provide as much information as TBB, with the
Evaluation of a prognostic score. Pneumocystis carinii pneumonia in HIV-infected patients.: Chest. 1995 Jan;107(1):107-12. Unique Identifier : AIDSLINE MED/95112604; Vanhems P; Toma E; Department of Social and Preventive Medicine, University of; Montreal.; STUDY OBJECTIVE: (1) To evaluate a clinical score predicting the early death from Pneumocystis carinii pneumonia (PCP) in HIV-infected patients and to compare it with lactate dehydrogenase (LDH) levels and Karnofsky s performance score. (2) To compare the association of this score and partial oxygen pressure (PaO2) at
CD4 T lymphocyte count and the radiographic presentation of pulmonary tuberculosis. A study of the relationship between these factors in patients with human immunodeficiency virus infection.: Chest. 1995 Jan;107(1):74-80. Unique Identifier : AIDSLINE MED/95112664; Keiper MD; Beumont M; Elshami A; Langlotz CP; Miller WT Jr; Department of Diagnostic Radiology, Hospital of the University of; Pennsylvania, Philadelphia 19104.; BACKGROUND: Pulmonary infection and tumor in the AIDS population has a variable clinical and radiographic presentation. The association between the radiographic presentation of pulmonary tuberculosis and CD4 T lymphocyte count in the HIV-infected patient is investigated in order to provide an empirical approach for ea
Knowledge, attitudes and beliefs of European injecting drug users concerning preventive measures for HIV.: Eur J Epidemiol. 1994 Apr;10(2):135-42. Unique Identifier : AIDSLINE MED/95113083; Richardson SC; Papaevangelou G; Ancelle-Park R; Panteion University of Social and Political Sciences, Athens,; Greece.; Strategies for controlling the HIV epidemic include education and information campaigns for intravenous drug users (IDUs), as for all high-risk groups, and the provision of various public health measures and treatment. These can only be effective if the IDU is aware of them and has a favourable image of them. A study
HTLV-I and HTLV-II infections among HIV-1 seropositive patients in Sao Paulo, Brazil.: Eur J Epidemiol. 1994 Apr;10(2):165-71. Unique Identifier : AIDSLINE MED/95113087; de Araujo AC; Casseb JS; Neitzert E; de Souza ML; Mammano F; Del Mistro A; De Rossi A; Chieco-Bianchi L; Department of Immunology, Instituto Adolfo Lutz, Sao Paulo,; Brazil.; To estimate the presence of, and the risk factors for HTLV-I and HTLV-II infections among HIV-1 infected subjects in Sao Paulo, Brazil , a serosurvey was performed in 471 HIV-1 infected patients, including 216 intravenous drug addicts (IVDA), 229 homosexual/bisexual men, and 26 with
Structural features of mag, a gypsy-like retrotransposon of Bombyx mori, with unusual short terminal repeats.: Genetica. 1994;93(1-3):125-37. Unique Identifier : AIDSLINE MED/95113316; Garel A; Nony P; Prudhomme JC; Universite Claude Bernard, Lyon 1, Centre de Genetique; Moleculaire et Cellulaire, UMR 106, Villeurbanne, France.; Mag is a retrotransposon found as an insert in the Sericin 2 gene. It is present in a few copies--4 to 15--dispersed in the genome of different strains of Bombyx mori as well as in Bombyx mandarina. Flanked by a 5 bp target sequence with no sequence specificity, it is bordered by direct repeats of 77 nucleotides. Desp
[Bacterial arthritis with E. coli in an elderly patient]: Harefuah. 1994 Dec 15;127(12):522-3, 575. Unique Identifier : AIDSLINE MED/95113336; Aharon A; Langevici P; Dept. of Medicine B, Chaim Sheba Medical Center, Tel Hashomer and; Sackler School of Medicine, Tel Aviv University.; Infectious arthritis is mostly caused by hematogenous spread of Gram-positive bacteria, which often infects a previously damaged joint. During the past 20 years there has been a notable increase in joint infections caused Gram-negative bacteria. They develop mostly in patients with systemic diseases, such as malignanc
[Human T cell lymphoma/leukemia virus type I]: Harefuah. 1994 Dec 15;127(12):543-7. Unique Identifier : AIDSLINE MED/95113345; Kilim Y; Danon YL
Laterality, sexual orientation, and immune system functioning: is there a relationship?: Int J Neurosci. 1994 Aug;77(3-4):167-80. Unique Identifier : AIDSLINE MED/95113636; Halpern DF; Cass M; Department of Psychology, California State University, San; Bernardino 92407.; There have been numerous recent investigations of the possibility that laterality (the extent to which an individual is right or left-sided or, more usually, right- or left-handed), sexual orientation (homosexual, bisexual, or heterosexual), and immune system functioning are related. The reasons for inconsistencies in
Immunological aspects of HCV infection.: Intervirology. 1994;37(2):119-25. Unique Identifier : AIDSLINE MED/95113670; Cerny A; Chisari FV; Department of Internal Medicine, University Hospital,; Inselspital, Bern, Switzerland.; The hepatitis C virus (HCV) commonly causes persistent infection and chronic liver disease, and it is an important risk factor for the development of hepatocellular carcinoma (HCC). The mechanisms responsible for HCV persistence and disease pathogenesis are not well understood, although it is likely that both direct (
HIV prevention: factors that predict compliance with testing and counseling procedures.: J Am Osteopath Assoc. 1994 Oct;94(10):825-30. Unique Identifier : AIDSLINE MED/95113714; Fry LJ; Fernandez RA; Division of Rural Health and Research, Nova Southeastern; University College of Osteopathic Medicine, North Miami Beach, FL; 33162.; Human immunodeficiency virus (HIV) testing and pretest/posttest counseling are central components in prevention efforts in the United States . Yet, not all persons return for their test results and posttest counseling. Based on an exploratory study at four community health centers in So
Clinical response to the addition of clarithromycin in Pneumocystis carinii pneumonia refractory to high dose co-trimoxazole [letter]: J Antimicrob Chemother. 1994 Aug;34(2):303. Unique Identifier : AIDSLINE MED/95113736; Price DA; Hollings NP; Janes SM; Main J; Coker RJ
Reassessment of the impact of mucosal immunity in infection with the human immunodeficiency virus (HIV) and design of relevant vaccines.: J Clin Immunol. 1994 Sep;14(5):259-72. Unique Identifier : AIDSLINE MED/95113926; Mestecky J; Jackson S; Department of Microbiology, UAB, Birmingham, Alabama 35294-2170.
Age-related ranges of memory, activation, and cytotoxic markers on CD4 and CD8 cells in children.: J Clin Immunol. 1994 Sep;14(5):289-98. Unique Identifier : AIDSLINE MED/95113929; Aldhous MC; Raab GM; Doherty KV; Mok JY; Bird AG; Froebel KS; HIV Immunology Unit, University Department of Medicine,; Edinburgh, Scotland.; The expression of markers defining functional subpopulations on the surface of CD4 and CD8 cells changes with disease. To monitor these changes in children, it is important to establish the age-related normal changes in marker expression due to maturation of the immune system. We have studied the expression of several
Molecular typing of Cryptococcus neoformans serotype D clinical isolates.: J Clin Microbiol. 1994 Oct;32(10):2364-71. Unique Identifier : AIDSLINE MED/95113938; Dromer F; Varma A; Ronin O; Mathoulin S; Dupont B; Unite de Mycologie, Institut Pasteur, France.; Cryptococcus neoformans serotype A is responsible for the majority of cryptococcal infections in AIDS patients. In France , approximately 17% of the patients are infected with serotype D, regardless of their human immunodeficiency virus status. In a retrospective study of 273 patien
Sensitivities of radioimmunoprecipitation assay and PCR for detection of human T-lymphotropic type II infection.: J Clin Microbiol. 1994 Oct;32(10):2464-7. Unique Identifier : AIDSLINE MED/95113955; Gallo D; Penning LM; Diggs JL; Hanson CV; Viral and Rickettsial Disease Laboratory, State of California; Department of Health Services, Berkeley 94704.; Five hundred forty-eight uncoagulated blood specimens from intravenous drug users infected with human T-lymphotropic virus type II (HTLV-II) were used to evaluate the sensitivities of the radioimmunoprecipitation assay (RIPA) and PCR for detecting HTLV-II-infected people. The sensitivities of both RIPA and PCR were fo
Multicenter evaluation of a fully automated screening test, VIDAS HIV 1 + 2, for antibodies to human immunodeficiency virus types 1 and 2.: J Clin Microbiol. 1994 Oct;32(10):2559-63. Unique Identifier : AIDSLINE MED/95113973; Azevedo-Pereira JM; Lourenco MH; Barin F; Cisterna R; Denis F; Moncharmont P; Grillo R; Santos-Ferreira MO; Laboratory of Virology, Faculty of Pharmacy, University of; Lisbon, Portugal.; A multicenter study was done to evaluate the sensitivity, specificity, and efficiency of a new screening test for the simultaneous detection of human immunodeficiency virus type 1 and 2 (HIV-1 and HIV-2) antibodies. The VIDAS HIV 1 + 2 (bioMerieux, Marcy l Etoile, France ) is a full
Optimum recovery of Mycobacterium avium complex from blood specimens of human immunodeficiency virus-positive patients by using small volumes of isolator concentrate inoculated into BACTEC 12B bottles [see comments]: J Clin Microbiol. 1994 Oct;32(10):2576-7. Unique Identifier : AIDSLINE MED/95113977; Doern GV; Westerling JA; Department of Hospital Laboratories, University of Massachusetts; Medical Center, Worcester 01655.; Recovery of Mycobacterium avium complex organisms from 412 lysis-centrifugation (Isolator) concentrates of blood specimens obtained from human immunodeficiency virus-positive individuals was attempted with the following media (and Isolator concentrate inoculum volumes): BACTEC 12B broth (0.2 and 1.0 ml), Lowenstein-Je
Evaluation of two commercial human T-cell lymphotropic virus western blot (immunoblot) kits with problem specimens.: J Clin Microbiol. 1994 Sep;32(9):2046-9. Unique Identifier : AIDSLINE MED/95114002; Gallo D; Diggs JL; Hanson CV; Viral and Rickettsial Disease Laboratory, State of California; Department of Health Services, Berkeley 94704.; We evaluated two commercial human T-cell lymphotropic virus (HTLV) Western blot (WB; immunoblot) kits, Cambridge Biotech Corp. (CBC) and Diagnostic Biotechnology Ltd. (DBL). Both methods employ HTLV type I (HTLV-I) viral lysate and rgp21. The DBL WB kit also distinguishes between HTLV-I and HTLV-II antibodies, using a
Emergence of fluconazole-resistant strains of Candida albicans in patients with recurrent oropharyngeal candidosis and human immunodeficiency virus infection.: J Clin Microbiol. 1994 Sep;32(9):2092-8. Unique Identifier : AIDSLINE MED/95114011; Ruhnke M; Eigler A; Tennagen I; Geiseler B; Engelmann E; Trautmann M; Abt. fur Hamatologie/Onkologie Universitatsklinikum Rudolf; Virchow/Charlottenburg, Freie Universitat Berlin, Germany.; After repeated use of fluconazole for therapy of oropharyngeal candidosis, the emergence of in vitro fluconazole-resistant Candida albicans isolates (MIC, > or = 25 micrograms/ml) together with oral candidosis unresponsive to oral dosages of up to 400 mg of fluconazole were observed in patients with human immunodefici
Quantification of human immunodeficiency virus type 1-infected mononuclear cells in peripheral blood of seropositive subjects by newly developed flow cytometry analysis of the product of an in situ PCR assay.: J Clin Microbiol. 1994 Sep;32(9):2152-7. Unique Identifier : AIDSLINE MED/95114021; Re MC; Furlini G; Gibellini D; Vignoli M; Ramazzotti E; Lolli E; Ranieri S; La Placa M; Institute of Microbiology, University of Bologna Medical School,; St. Orsola General Hospital, Italy.; The presence of human immunodeficiency virus type 1 (HIV-1) proviral DNA in peripheral blood mononuclear cells (PBMC) of three groups (group 1, more than 500 CD4+ T cells per microliter; group 2, between 200 and 499 CD4+ T cells per microliter; group 3, fewer than 200 CD4+ T cells per microliter) of HIV-1-infected pat
Elimination of false-positive serum reactivity in latex agglutination test for cryptococcal antigen in human immunodeficiency virus-infected population.: J Clin Microbiol. 1994 Sep;32(9):2158-61. Unique Identifier : AIDSLINE MED/95114022; Whittier S; Hopfer RL; Gilligan P; Clinical Microbiology-Immunology Laboratories, University of; North Carolina Hospitals, Chapel Hill.; We recently tested serum from a human immunodeficiency virus-infected patient for the presence of cryptococcal antigen using the Meridian latex agglutination (LA) test (Cryptococcal Antigen Latex Agglutination System). Two pronase-treated serum specimens from the patient had LA titers of 80 and 160, but the patient ha
Stabilities of quantitative plasma culture for human immunodeficiency virus, RNA, and p24 antigen from samples collected in VACUTAINER CPT and standard VACUTAINER tubes.: J Clin Microbiol. 1994 Sep;32(9):2212-5. Unique Identifier : AIDSLINE MED/95114032; Mole L; Margolis D; Carroll R; Todd J; Holodniy M; ARC-AIDS Research Center, Veterans Affairs Medical Center, Palo; Alto, California 94304.; We evaluated the stability of human immunodeficiency virus (HIV) load markers from blood samples collected in VACUTAINER CPT or standard VACUTAINER brand tubes using sodium heparin or sodium citrate as anticoagulants. Quantitative plasma culture and p24 antigen concentrations were determined, and HIV RNA levels in pla
Distribution of viral genotypes in Italy determined by hepatitis C virus typing by DNA immunoassay.: J Clin Microbiol. 1994 Sep;32(9):2280-4. Unique Identifier : AIDSLINE MED/95114046; Ravaggi A; Zonaro A; Marin MG; Puoti M; Albertini A; Cariani E; Institute of Chemistry, School of Medicine, University of; Brescia, Italy.; The distribution of hepatitis C virus (HCV) genotypes in Italy was investigated by PCR amplification of the E1 region and hybridization with type I- and type II-specific nonisotopic probes. Positive PCR results were obtained for 65 of 72 patients (90.3%). Type I was detected in 13 o
Standardized microtiter assay for determination of syncytium-inducing phenotypes of clinical human immunodeficiency virus type 1 isolates.: J Clin Microbiol. 1994 Sep;32(9):2291-4. Unique Identifier : AIDSLINE MED/95114049; Japour AJ; Fiscus SA; Arduino JM; Mayers DL; Reichelderfer PS; Kuritzkes DR; Department of Medicine, Beth Israel Hospital, Boston,; Massachusetts 02215.; A standardized assay in 96-well microtiter plates for syncytium-inducing (SI) human immunodeficiency virus type 1 phenotype detection using MT-2 cells has been developed. SI variants were found in 67% of the patients with advanced human immunodeficiency virus disease. The occurrence of the SI phenotype increased with
Evaluation of new monoclonal antibody-based latex agglutination test for detection of cryptococcal polysaccharide antigen in serum and cerebrospinal fluid.: J Clin Microbiol. 1994 Sep;32(9):2309-11. Unique Identifier : AIDSLINE MED/95114055; Kiska DL; Orkiszewski DR; Howell D; Gilligan PH; Clinical Microbiology Laboratory, University of North Carolina; Hospitals, Chapel Hill 27514.; We evaluated the performance of CRYPTO-LEX (Trinity Laboratories, Inc., Raleigh, N. C.), a new mouse immunoglobulin M monoclonal antibody latex agglutination reagent which reacts with the capsular polysaccharide of the four serogroups of Cryptococcus neoformans. This test was compared with CALAS (Meridian Diagnostics,
Usefulness of PCR for detection of Pneumocystis carinii DNA [see comments]: J Clin Microbiol. 1994 Sep;32(9):2324-6. Unique Identifier : AIDSLINE MED/95114060; Roux P; Lavrard I; Poirot JL; Chouaid C; Denis M; Olivier JL; Nigou M; Miltgen M; Laboratoire de Parasitologie, CHU Saint-Antonie, Paris.; Diagnosis of Pneumocystis carinii pneumonia is based on the identification of the various stages of the parasite in lung samples by standard staining techniques. We therefore assessed the value of the PCR for detection of P. carinii in bronchoalveolar lavage, induced sputum, and blood samples relative to that of stand
Demonstration of persistence of Salmonella typhimurium in an AIDS patient by molecular methods.: J Clin Microbiol. 1994 Sep;32(9):2327-30. Unique Identifier : AIDSLINE MED/95114061; Fica AE; Horowitz HW; Lior H; Cabello FC; Department of Microbiology and Immunology, New York Medical; College, Valhalla.; We document microbiological persistence of the same Salmonella typhimurium strain in an AIDS patient during 7 months of clinical observation despite prolonged quinolone therapy. Persistence was demonstrated by phage types that closely resembled one another, similar antibiotic resistance patterns, conserved restriction
Utility of quantitative enzyme immunoassay reactivity for predicting human immunodeficiency virus seropositivity in low- and high-prevalence populations [letter; comment]: J Clin Microbiol. 1994 Sep;32(9):2340-1. Unique Identifier : AIDSLINE MED/95114067; Michalski FJ
Cytotoxic and proliferative T cell responses in HIV-1-infected Macaca nemestrina.: J Clin Invest. 1995 Jan;95(1):248-56. Unique Identifier : AIDSLINE MED/95114116; Kent SJ; Corey L; Agy MB; Morton WR; McElrath MJ; Greenberg PD; Department of Medicine, University of Washington, Seattle 98195.; Macaca nemestrina has been described as an animal model for acute HIV-1 infection. This animal, unlike most infected humans, appears to contain HIV-1 replication. Therefore analysis of HIV-1-specific proliferative and cytotoxic T lymphocyte (CTL) responses following HIV-1 challenge of M. nemestrina may provide informa
Mutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma.: J Clin Invest. 1995 Jan;95(1):257-63. Unique Identifier : AIDSLINE MED/95114117; Wolf DG; Smith IL; Lee DJ; Freeman WR; Flores-Aguilar M; Spector SA; University of California, San Diego, Department of Pediatrics,; San Diego, La Jolla 92093-0672.; Specific mutations in the UL97 region of human cytomegalovirus (HCMV) have been found to confer resistance to laboratory-adapted strains subjected to ganciclovir selection. In this study, mutations in the UL97 region of HCMV isolates obtained from patients receiving ganciclovir the
Tat-independent replication of human immunodeficiency viruses.: J Clin Invest. 1995 Jan;95(1):328-32. Unique Identifier : AIDSLINE MED/95114129; Luznik L; Kraus G; Guatelli J; Richman D; Wong-Staal F; Department of Medicine, University of California, School of; Medicine, San Diego 92093.; The replication of human immunodeficiency retroviruses involves a complex series of events that is regulated at both transcriptional and posttranscriptional levels. The tat gene product is a potent trans-activator of viral transcription and therefore an attractive target for the development of antiviral drugs. Tat-def
The treatment effect of alpha interferon in chronic hepatitis B is independent of pre-treatment variables. Results based on individual patient data from 10 clinical controlled trials. European Concerted Action on Viral Hepatitis (Eurohep).: J Hepatol. 1994 Oct;21(4):646-55. Unique Identifier : AIDSLINE MED/95114321; Krogsgaard K; Bindslev N; Christensen E; Craxi A; Schlichting P; Schalm S; Carreno V; Trepo C; Gerken G; Thomas HC; et al; Department of Infectious Diseases, Rigshospitalet, University of; Copenhagen, Denmark.; Alpha interferon induces HBeAg seroconversion in about one third of treated patients and has become an established treatment of chronic hepatitis B. A number of smaller studies have suggested that response to treatment is more likely to occur in patients with higher levels of transaminases, with recent (adult) onset,
Dermatologic manifestations of sexually transmitted diseases other than HIV.: Infect Dis Clin North Am. 1994 Sep;8(3):533-82. Unique Identifier : AIDSLINE MED/95114344; Martin DH; Mroczkowski TF; Department of Medicine, Louisiana State University School of; Medicine, New Orleans 70112.; This article focuses on the common skin manifestations of sexually transmitted diseases. A number of unusual skin lesions associated with these diseases are shown, and pathogenesis and treatment are briefly presented. This article will be most useful as a reference for the formulation of the differential diagnosis of
Dermatologic manifestations of HIV infection and AIDS.: Infect Dis Clin North Am. 1994 Sep;8(3):583-605. Unique Identifier : AIDSLINE MED/95114345; Ray MC; Gately LE 3rd; Ochsner Medical Institutions, New Orleans, Louisiana.; Infection with HIV can result in many cutaneous disorders, some of which may be the presenting sign of the disease. The cutaneous manifestations may be infectious or noninfectious. This article reviews the numerous cutaneous infectious findings, neoplasms, and dermatoses seen in HIV-infected individuals.
Activation-induced CD4+ T cell death by apoptosis in experimental Chagas' disease.: J Immunol. 1995 Jan 15;154(2):744-52. Unique Identifier : AIDSLINE MED/95114400; Lopes MF; da Veiga VF; Santos AR; Fonseca ME; DosReis GA; Department of Immunology, Federal University of Rio de Janeiro,; Brazil.; Infection of mice with Trypanosoma cruzi, the causative protozoan agent of human Chagas disease, leads to immunosuppression of the T cell compartment and to chronic cardiac inflammation which resembles the human infection. Recently, reinduction of programmed cell death by apoptosis in mature T cells has been demonstr
Divergent effects of chronic HIV-1 infection on human thymocyte maturation in SCID-hu mice.: J Immunol. 1995 Jan 15;154(2):907-21. Unique Identifier : AIDSLINE MED/95114417; Kollman TR; Kim A; Pettoello-Mantovani M; Hachamovitch M; Rubinstein A; Goldstein MM; Goldstein H; Department of Microbiology and Immunology, Albert Einstein; College of Medicine, Bronx, NY 10461.; We have recently developed a modified SCID-hu mouse model in which the implanted human thymus and liver (hu-thy/liv) and human peripheral T cells become infected with HIV-1 after i.p. inoculation. By using this model, we evaluated the effect of HIV-1 infection on thymic maturation and observed that different HIV-1 str
TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines.: J Immunol. 1995 Jan 15;154(2):944-53. Unique Identifier : AIDSLINE MED/95114421; Renno T; Krakowski M; Piccirillo C; Lin JY; Owens T; Montreal Neurological Institute, Quebec, Canada.; The inflammatory cytokines IFN-gamma and TNF-alpha have been demonstrated in various autoimmune diseases, and are thought to participate in the induction and pathogenesis of disease. TFN-alpha is a cytopathic cytokine that is cytotoxic for oligodendrocytes in vitro and has been implicated in the pathology of multiple
[AIDS and lung diseases--special reference to Pneumocystis carinii pneumonia]: Nippon Naika Gakkai Zasshi. 1994 Oct 10;83(10):1834-40. Unique Identifier : AIDSLINE MED/95114493; Goto H
Cancer in children with primary or secondary immunodeficiencies [see comments]: J Pediatr. 1995 Jan;126(1):1-10. Unique Identifier : AIDSLINE MED/95114743; Mueller BU; Pizzo PA; Pediatric Branch, National Cancer Institute, Bethesda, Maryland; 20892-1928.
Using a health education approach to develop and evaluate a program for parents of children with human immunodeficiency virus infection.: J Pediatr Nurs. 1994 Oct;9(5):343-4. Unique Identifier : AIDSLINE MED/95114847; Schwartz PL; Hirtz SA; Texas Children's Hospital, Houston, 77030.
Genetic analysis of human immunodeficiency virus type 1 envelope V3 region isolates from mothers and infants after perinatal transmission.: J Virol. 1995 Feb;69(2):1001-12. Unique Identifier : AIDSLINE +; Ahmad N; Baroudy BM; Baker RC; Chappey C; Division of Molecular Virology, James N. Gamble Institute of; Medical Research, Cincinnati, Ohio 45219.; The human immunodeficiency virus type 1 (HIV-1) sequences from variable region 3 (V3) of the envelope gene were analyzed from seven infected mother-infant pairs following perinatal transmission. The V3 region sequences directly derived from the DNA of the uncultured peripheral blood mononuclear cells from infected mot
Proteinase-resistant factors in human erythrocyte membranes mediate CD4-dependent fusion with cells expressing human immunodeficiency virus type 1 envelope glycoproteins.: J Virol. 1995 Feb;69(2):1013-8. Unique Identifier : AIDSLINE MED/95115055; Dragic T; Picard L; Alizon M; Institut National de la Sante et de la Recherche Medicale U332,; Institut Cochin de Genetique Moleculaire, Paris, France.; Murine CD4+ cells are resistant to human immunodeficiency virus type 1 (HIV-1) entry and to fusion with cells expressing HIV-1 envelope glycoproteins (Env). The role of human-specific factors in Env/CD4-mediated fusion is shown by the ability of transient cell hybrids formed between CD4+ murine cells and human HeLa ce
Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression.: J Virol. 1995 Feb;69(2):1059-70. Unique Identifier : AIDSLINE MED/95115062; Borrow P; Evans CF; Oldstone MB; Department of Neuropharmacology, Scripps Research Institute, La; Jolla, California 92037.; Despite the clinical importance of virus-induced immunosuppression, how virus infection may lead to a generalized suppression of the host immune response is poorly understood. To elucidate the principles involved, we analyzed the mechanism by which a lymphocytic choriomeningitis virus (LCMV) variant produces a general
Efficient in vivo and in vitro assembly of retroviral capsids from Gag precursor proteins expressed in bacteria.: J Virol. 1995 Feb;69(2):1093-8. Unique Identifier : AIDSLINE MED/95115066; Klikova M; Rhee SS; Hunter E; Ruml T; Department of Biochemistry and Microbiology, Institute of; Chemical Technology, Prague, Czech Republic.; The capsid precursor protein (Gag) of Mason- Pfizer monkey virus, the prototype type D retrovirus, has been expressed to high levels in bacteria under the control of the phage T7 promoter. Electron microscopic studies of induced cells revealed the assembly of capsid-like st
Structural interactions between retroviral Gag proteins examined by cysteine cross-linking.: J Virol. 1995 Feb;69(2):1150-9. Unique Identifier : AIDSLINE MED/95115073; Hansen MS; Barklis E; Vollum Institute for Advanced Biomedical Research, Oregon Health; Sciences University, Portland 97201-3098.; We have examined structural interactions between Gag proteins within Moloney murine leukemia virus (M-MuLV) particles by making use of the cysteine-specific cross-linking agents iodine and bis-maleimido hexane. Virion-associated wild-type M-MuLV Pr65Gag proteins in immature particles were intermolecularly cross-linked
Determinants of human immunodeficiency virus type 1 envelope glycoprotein oligomeric structure.: J Virol. 1995 Feb;69(2):1209-18. Unique Identifier : AIDSLINE MED/95115079; Poumbourios P; el Ahmar W; McPhee DA; Kemp BE; St. Vincent's Institute of Medical Research, Fitzroy, Victoria,; Australia.; Oligomerization of the human immunodeficiency virus type 1 envelope (env) glycoproteins is mediated by the ectodomain of the transmembrane glycoprotein gp41. We report that deletion of gp41 residues 550 to 561 resulted in gp41 sedimenting as a monomer in sucrose gradients, while the gp160 precursor sedimented as a mix
Extracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency.: J Virol. 1995 Feb;69(2):1243-52. Unique Identifier : AIDSLINE MED/95115082; Levy DN; Refaeli Y; Weiner DB; Department of Pathology and Laboratory Medicine, University of; Pennsylvania, Philadelphia 19104-4283.; The vpr gene product of human immunodeficiency virus (HIV) and simian immunodeficiency virus is a virion-associated regulatory protein that has been shown using vpr mutant viruses to increase virus replication, particularly in monocytes/macrophages. We have previously shown that vpr can directly inhibit cell prolifera
Protection against homologous but not heterologous challenge induced by inactivated feline immunodeficiency virus vaccines.: J Virol. 1995 Feb;69(2):1253-5. Unique Identifier : AIDSLINE MED/95115083; Hosie MJ; Osborne R; Yamamoto JK; Neil JC; Jarrett O; Department of Veterinary Pathology, University of Glasgow,; Bearsden, Scotland.; Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8) which is distinct from the Petaluma strain in virus neutralization. Protection was associated with a type-specific neutra
Regions required for CD4 binding in the external glycoprotein gp120 of simian immunodeficiency virus.: J Virol. 1995 Feb;69(2):1256-60. Unique Identifier : AIDSLINE MED/95115084; Doyle CB; Bhattacharyya U; Kent KA; Stott JE; Jones IM; NERC Institute of Virology, Oxford United Kingdom.; The external domain of the envelope glycoprotein, gp120, of simian immunodeficiency virus (SIV) has been expressed as a mature secreted product using recombinant baculoviruses and the expressed protein, which has an observed molecular mass of 110 kDa, was purified by monoclonal antibody (MAb) affinity chromatography.
Induction of interleukin-10 by human immunodeficiency virus type 1 and its gp120 protein in human monocytes/macrophages.: J Virol. 1995 Feb;69(2):1284-7. Unique Identifier : AIDSLINE MED/95115090; Borghi P; Fantuzzi L; Varano B; Gessani S; Puddu P; Conti L; Capobianchi MR; Ameglio F; Belardelli F; Laboratory of Virology, University La Sapienza, Rome, Italy.; In this study, we evaluated the effects of human immunodeficiency virus type 1 (HIV-1) and its gp120 protein on interleukin-10 (IL-10) expression in cultured human monocytes/macrophages. Infection of either 1-day monocytes or 7-day monocyte-derived macrophages with HIV-1 strain Ba-L resulted in clear-cut accumulation
Effects of the simian virus 40 origin of replication on transcription from the human immunodeficiency virus type 1 promoter.: J Virol. 1995 Feb;69(2):1296-301. Unique Identifier : AIDSLINE MED/95115093; Nahreini P; Mathews MB; Cold Spring Harbor Laboratory, New York 11724.; Positive and negative effects of DNA replication on gene transcription have been documented in a variety of systems. We examined the effects of the simian virus 40 (SV40) origin of replication on transcription from the human immunodeficiency virus type 1 (HIV-1) promoter, using a transient expression assay in COS-1 ce
Intrauterine transmission of human T-cell leukemia virus type I in rats.: J Virol. 1995 Feb;69(2):1302-5. Unique Identifier : AIDSLINE MED/95115094; Hori M; Ami Y; Kushida S; Kobayashi M; Uchida K; Abe T; Miwa M; Department of Biochemistry, University of Tsukuba, Ibaraki,; Japan.; To analyze intrauterine transmission, MT-2 cells, a human T-cell line producing human T-cell leukemia virus type I (HTLV-I), were injected into eight pregnant F344 rats, and cesarean section was performed at day 23 of pregnancy. HTLV-I provirus was detected by PCR in the liver and spleen taken from one of the eight fe
Evidence for coinfection by multiple strains of human immunodeficiency virus type 1 subtype B in an acute seroconvertor.: J Virol. 1995 Feb;69(2):1324-7. Unique Identifier : AIDSLINE GENBANK/U16388; Zhu T; Wang N; Carr A; Wolinsky S; Ho DD; Aaron Diamond AIDS Research Center, New York University School of; Medicine, New York 10016.; Sequences encoding the envelope glycoprotein of human immunodeficiency virus type 1 (HIV-1) were amplified by PCR from plasma and peripheral blood mononuclear cells obtained at four time points from an acute seroconvertor. Genetic analyses, including nucleotide sequencing and heteroduplex mobility studies, showed that
Potential role of natural killer cells in controlling tumorigenesis by human T-cell leukemia viruses.: J Virol. 1995 Feb;69(2):1328-33. Unique Identifier : AIDSLINE MED/95115100; Feuer G; Stewart SA; Baird SM; Lee F; Feuer R; Chen IS; Department of Medicine, UCLA School of Medicine.; Human T-cell leukemia virus (HTLV) is the etiologic agent of adult T-cell leukemia (ATL), a malignancy of T lymphocytes that is characterized by a long latency period after virus exposure. Intraperitoneal inoculation of severe combined immunodeficient (SCID) mice with HTLV-transformed cell lines and ATL tumor cells wa
Effects of second-site mutations on dominant interference by a human immunodeficiency virus type 1 envelope glycoprotein mutant.: J Virol. 1995 Feb;69(2):1344-8. Unique Identifier : AIDSLINE MED/95115103; Buchschacher GL Jr; Freed EO; Panganiban AT; McArdle Laboratory for Cancer Research, University of Wisconsin,; Madison 53706.; We have demonstrated previously that a human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein containing a Val-to-Glu substitution at the second amino acid of the transmembrane glycoprotein gp41 (termed the 41.2 mutant) dominantly interferes with wild-type envelope-mediated syncytium formation and virus inf
Identification of a new viral protein containing CAp30 and NCp10 sequences in murine and feline leukemia retroviruses.: J Virol. 1995 Feb;69(2):1353-8. Unique Identifier : AIDSLINE MED/95115105; Meyer MK; Nash MA; Arlinghaus RB; Department of Molecular Pathology, University of Texas M. D.; Anderson Cancer Center, Houston 77030.; Because Pr65gag is in part located in the nucleus and contains a putative bipartite nuclear targeting signal, we investigated the cellular location and structure of P55gag, a gag-encoded polyprotein known to lack the nucleocapsid (NC) protein NCp10. P55gag was found to be restricted to the cytoplasm of Moloney murine
Encapsidation and serial passage of a poliovirus replicon which expresses an inactive 2A proteinase.: J Virol. 1995 Feb;69(2):1359-66. Unique Identifier : AIDSLINE MED/95115106; Ansardi DC; Pal-Ghosh R; Porter D; Morrow CD; Department of Microbiology, University of Alabama at Birmingham; 35294.; The multiple roles of the viral proteinase 2A in poliovirus replication have been difficult to assess because, to date, it has not been possible to isolate and characterize a viral genome with an inactive 2Apro. We have previously reported that a poliovirus replicon containing an inactive 2Apro by virtue of a change a
Simian immunodeficiency virus SIVmac chimeric virus whose env gene was derived from SIV-encephalitic brain is macrophage-tropic but not neurovirulent.: J Virol. 1995 Feb;69(2):1367-9. Unique Identifier : AIDSLINE MED/95115107; Joag SV; Stephens EB; Galbreath D; Zhu GW; Li Z; Foresman L; Zhao LJ; Pinson DM; Narayan O; Marion Merrell Dow Laboratory of Viral Pathogenesis, Department; of Microbiology, University of Kansas Medical Center, Kansas City; 66160-7424.; We inoculated four rhesus macaques with molecularly cloned simian immunodeficiency virus SIVmac239/17E env, a chimeric virus whose env gene was derived from the brain of an SIV-encephalitic macaque. Blood and lymphoid tissues had high frequencies of infected cells. The virus was neuroinvasive, but productive virus rep
Phylogenetic relationship and geographic distribution of multiple human T-cell lymphotropic virus type II subtypes.: J Virol. 1995 Feb;69(2):621-32. Unique Identifier : AIDSLINE GENBANK/U10266; Switzer WM; Pieniazek D; Swanson P; Samdal HH; Soriano V; Khabbaz RF; Kaplan JE; Lal RB; Heneine W; Retrovirus Diseases Branch, Centers for Disease Control and; Prevention, Atlanta, Georgia 30333.; The current env-based subtyping of human T-cell lymphotropic virus type II (HTLV-II) identifies only two heterogenetic groups, HTLV-IIa and HTLV-IIb. To better understand the genetic diversity and phylogeny of HTLV-II, we examined the most divergent genomic region of HTLV-II, the long terminal repeat, by using restric
Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity.: J Virol. 1995 Feb;69(2):642-50. Unique Identifier : AIDSLINE MED/95115111; Reicin AS; Paik S; Berkowitz RD; Luban J; Lowy I; Goff SP; Department of Medicine, College of Physicians and Surgeons,; Columbia University, New York, New York 10032.; The phenotypes of a series of mutant human immunodeficiency virus type 1 proviruses with linker insertion and deletion mutations within the gag coding region were characterized. These mutants were tested for their ability to make and release viral particles in COS7 cells and for their viability in vivo. Of the 12 muta
Selection and analysis of human immunodeficiency virus type 1 variants with increased resistance to ABT-538, a novel protease inhibitor.: J Virol. 1995 Feb;69(2):701-6. Unique Identifier : AIDSLINE MED/95115118; Markowitz M; Mo H; Kempf DJ; Norbeck DW; Bhat TN; Erickson JW; Ho DD; Aaron Diamond AIDS Research Center, New York University School of; Medicine, New York 10016.; Inhibitors of the human immunodeficiency virus protease represent a promising new class of antiretroviral drugs for the treatment of AIDS. We now report the in vitro selection of viral variants with decreased sensitivity to a symmetry-based protease inhibitor, ABT-538, currently being tested in clinical trials. Molecu
Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses.: J Virol. 1995 Feb;69(2):773-8. Unique Identifier : AIDSLINE MED/95115128; van Doorn LJ; Capriles I; Maertens G; DeLeys R; Murray K; Kos T; Schellekens H; Quint W; Department of Molecular Biology, Diagnostic Centre SSDZ, Delft,; The Netherlands.; Sequence evolution of the hypervariable region 1 (HVR1) in the N terminus of E2/NS1 of hepatitis C virus (HCV) was studied retrospectively in six chimpanzees inoculated with the same genotype 1b strain, containing a unique predominant HVR1 sequence. Immediately after inoculation, all animals contained the same HVR pre
HPRS-103 (exogenous avian leukosis virus, subgroup J) has an env gene related to those of endogenous elements EAV-0 and E51 and an E element found previously only in sarcoma viruses.: J Virol. 1995 Feb;69(2):779-84. Unique Identifier : AIDSLINE GENBANK/Z46390; Bai J; Payne LN; Skinner MA; Division of Molecular Biology, Institute for Animal Health,; Compton, Berkshire, United Kingdom.; The avian leukosis and sarcoma virus (ALSV) group comprises eight subgroups based on envelope properties. HPRS-103, an exogenous retrovirus recently isolated from meat-type chicken lines, is similar to the viruses of these subgroups in group antigen but differs from them in envelope properties and has been assigned to
A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate.: J Virol. 1995 Feb;69(2):796-800. Unique Identifier : AIDSLINE MED/95115131; Baldanti F; Silini E; Sarasini A; Talarico CL; Stanat SC; Biron KK; Furione M; Bono F; Palu G; Gerna G; Virus Laboratory, University of Pavia, IRCCS Policlinico S.; Matteo, Italy.; Multiple human cytomegalovirus (HCMV) strains frequently coexist in patients with AIDS, and chronic ganciclovir treatment may favor the emergence of ganciclovir-resistant viral mutants. We report the molecular and biochemical characterization of a HCMV ganciclovir-resistant strain
Human foamy virus Bel1 transactivator contains a bipartite nuclear localization determinant which is sensitive to protein context and triple multimerization domains.: J Virol. 1995 Feb;69(2):801-8. Unique Identifier : AIDSLINE MED/95115132; Chang J; Lee KJ; Jang KL; Lee EK; Baek GH; Sung YC; Department of Life Science, Pohang University of Science and; Technology, Republic of Korea.; The Bel1 protein of human foamy virus is a 300-amino-acid nuclear regulatory protein which transactivates the gene expression directed by the homologous long terminal repeat and the human immunodeficiency virus type 1 long terminal repeat. While previous reports suggested that the single basic domain of Bel1 from resi
Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus type 1 (HIV-1): interference with early and late events in HIV-1 replication.: J Virol. 1995 Feb;69(2):814-24. Unique Identifier : AIDSLINE MED/95115134; Steinkasserer A; Harrison R; Billich A; Hammerschmid F; Werner G; Wolff B; Peichl P; Palfi G; Schnitzel W; Mlynar E; et al; Sandoz Forschungsinstitut GmbH, Vienna, Austria.; SDZ NIM 811 is a cyclosporin A analog that is completely devoid of immunosuppressive capacity but exhibits potent and selective anti-human immunodeficiency virus type 1 (HIV-1) activity. The mechanism of action of SDZ NIM 811 is clearly different from those of all other anti-HIV agents described so far. In cell-free a
Deletions in one domain of the Friend virus-encoded membrane glycoprotein overcome host range restrictions for erythroleukemia.: J Virol. 1995 Feb;69(2):856-63. Unique Identifier : AIDSLINE MED/95115139; Hoatlin ME; Ferro FE Jr; Geib RW; Fox MT; Kozak SL; Kabat D; Department of Biochemistry and Molecular Biology, Oregon Health; Sciences University, Portland 97201-3098.; Although the Friend virus-encoded membrane glycoprotein (gp55) activates erythropoietin receptors (EpoR) to cause erythroblastosis only in certain inbred strains of mice but not in other species, mutant viruses can overcome aspects of mouse resistance. Thus, mice homozygous for the resistance allele of the Fv-2 gene a
The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection.: J Virol. 1995 Feb;69(2):882-8. Unique Identifier : AIDSLINE MED/95115142; Rogel ME; Wu LI; Emerman M; Program in Molecular Medicine, Fred Hutchinson Cancer Research; Center, Seattle, Washington 98104.; Human immunodeficiency virus type 1 (HIV-1) is a retrovirus that can cause extensive cytopathicity in T cells. However, long-term productive infection of T-cell lines has been described. Here we show that although Vpr has no effect on the initial cytopathic effect of HIV-1, viruses that contain an intact vpr gene are
Immunopathogenic role of T-cell subsets in Borna disease virus-induced progressive encephalitis.: J Virol. 1995 Feb;69(2):896-903. Unique Identifier : AIDSLINE MED/95115144; Planz O; Bilzer T; Stitz L; Institut fur Virologie, Justus-Liebig-Universitat, Giessen,; Germany.; Borna disease is an immunopathological virus-induced encephalopathy comprising severe inflammation and degenerative brain cell lesions which results in organ atrophy and chronic debility in rats. CD4+ and CD8+ T cells have been reported to be involved in the development of this disease of the central nervous system. A
Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication.: J Virol. 1995 Feb;69(2):955-67. Unique Identifier : AIDSLINE MED/95115151; Hirsch VM; Dapolito G; Johnson PR; Elkins WR; London WT; Montali RJ; Goldstein S; Brown C; Immunodeficiency Viruses Section, National Institute of Allergy; and Infectious Diseases, NIH, Rockville, MD 20852.; Previous studies suggested that simian immunodeficiency viruses isolated from African green monkeys (SIVagm) are relatively nonpathogenic. The report describes the isolation and biologic and molecular characterization of a pathogenic SIVagm strain derived from a naturally infected African green monkey. This virus indu
HTLV-1 proviral DNA in oral aspirates of newborns born to seropositive mothers [letter]: JAMA. 1995 Jan 25;273(4):284. Unique Identifier : AIDSLINE MED/95115240; Sawada T; Taguchi T; Miyoshi I; Nakachi H; Nagayama T
Health status and function with zidovudine or zalcitabine as initial therapy for AIDS. A randomized controlled trial. Roche 3300/ACTG 114 Study Group.: JAMA. 1995 Jan 25;273(4):295-301. Unique Identifier : AIDSLINE MED/95115248; Bozzette SA; Kanouse DE; Berry S; Duan N; Health Sciences Program, RAND, Santa Monica, CA 90407-2138.; OBJECTIVE--To evaluate the functional and health status implications of prescribing zalcitabine or zidovudine for initial therapy of acquired immunodeficiency syndrome (AIDS). DESIGN--A substudy of a randomized controlled trial. SETTING--Private and public clinics and referral centers. PATIENTS--Had human immunodefici
Primary care approach to the newly diagnosed HIV-positive patient.: Kans Med. 1994 Oct;95(10):221-5. Unique Identifier : AIDSLINE MED/95115370; Johnson BE; Dept. of Internal Medicine, KUMC-KC 66160-7376.
Hepatitis E virus and HIV infection in homosexual men [letter; comment]: Lancet. 1995 Jan 14;345(8942):126-7. Unique Identifier : AIDSLINE MED/95115469; Nandwani R
HIV telephone consultation service [news]: Md Med J. 1994 Dec;43(12):1040. Unique Identifier : AIDSLINE MED/95115514
Newborn baby AIDS vaccine program [news]: Md Med J. 1994 Dec;43(12):1040. Unique Identifier : AIDSLINE MED/95115515
The yeast killer phenomenon: a hypothetical way to control Pneumocystis carinii pneumonia.: Med Hypotheses. 1994 Sep;43(3):167-71. Unique Identifier : AIDSLINE MED/95115587; Cailliez JC; Seguy N; Aliouat EM; Polonelli L; Camus D; Dei-Cas E; Unite 42 INSERM, Villeneuve d'Ascq, France.; Pneumocystis carinii is an important agent of pneumonia in immunocompromised individuals, especially in acquired immunodeficiency syndrome AIDS patients P. carinii attaches specifically to type 1 pneumocytes. Although this phenomenon must play a marked role in pneumocystosis pathophysiology, no therapeutic molecules a
The role of immunoglobulin binding factors in the pathogenesis and therapy of AIDS.: Med Hypotheses. 1994 Sep;43(3):172-6. Unique Identifier : AIDSLINE MED/95115588; Cowan FM; Madsen JM; Uppsala Inc., Colora, MD 21917.; The human immunodeficiency virus (HIV) gp120 and gp41 envelope proteins and Staphylococcus aureus protein A (SPA) all have Fc receptor (FcR)-like immunoglobulin binding factor (IBF) activity for the Fc constant fragments of human immunoglobulin G (IgG). Viral IBF may contribute to the pathology of HIV by jamming the n
High risk postmortems [editorial]: Med Leg J. 1994;62 ( Pt 3):97-9. Unique Identifier : AIDSLINE MED/95115594; Shepherd RT
Oral supplements in HIV-infected patients with chronic wasting. A prospective trial.: Med Klin. 1994 Nov 15;89(11):579-81, 633. Unique Identifier : AIDSLINE MED/95115598; Burger B; Schwenk A; Junger H; Ollenschlager G; Wessel D; Diehl V; Schrappe M; Department of Internal Medicine, University of Cologne, Germany.; AIM: Supplementation with polymeric formula diet was evaluated as second step of a nutritional intervention program for malnourished, but otherwise clinically stable HIV-infected patients. PATIENTS AND METHODS: 34 patients with weight loss, without opportunistic infections, diarrhea or fever, not responding to nutriti
Drug malabsorption and resistant tuberculosis in HIV-infected patients [letter]: N Engl J Med. 1995 Feb 2;332(5):336-7. Unique Identifier : AIDSLINE MED/95115735; Patel KB; Belmonte R; Crowe HM
AIDS. Virological mayhem [news; comment]: Nature. 1995 Jan 12;373(6510):102. Unique Identifier : AIDSLINE MED/95115741; Wain-Hobson S
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection [see comments]: Nature. 1995 Jan 12;373(6510):123-6. Unique Identifier : AIDSLINE MED/95115751; Ho DD; Neumann AU; Perelson AS; Chen W; Leonard JM; Markowitz M; Aaron Diamond AIDS Research Center, NYU School of Medicine, New; York 10016.; Treatment of infected patients with ABT-538, an inhibitor of the protease of human immunodeficiency virus type 1 (HIV-1), causes plasma HIV-1 levels to decrease exponentially (mean half-life, 2.1 +/- 0.4 days) and CD4 lymphocyte counts to rise substantially. Minimum estimates of HIV-1 production and clearance and of C
Duesberg and the new view of HIV [news] [see comments]: Nature. 1995 Jan 19;373(6511):189. Unique Identifier : AIDSLINE MED/95115781; Maddox J
Differential production of interferon-gamma and interleukin-4 in response to Th1- and Th2-stimulating pathogens by gamma delta T cells in vivo.: Nature. 1995 Jan 19;373(6511):255-7. Unique Identifier : AIDSLINE MED/95115801; Ferrick DA; Schrenzel MD; Mulvania T; Hsieh B; Ferlin WG; Lepper H; Department of Pathology, Microbiology and Immunology, School of; Veterinary Medicine, University of California, Davis 95616.; Exposure to various pathogens can stimulate at least two patterns of cytokine production by CD4-positive T cells. Responses that result in secretion of interferon-gamma (IFN-gamma), lymphotoxin and interleukin-2 ( IL-2 ) are classified as T-helper-1 (Th1); CD4+ T-cell pr
Care of the newly-diagnosed HIV positive patient [news]: Nurse Pract. 1994 Oct;19(10):4, 7-8, 11. Unique Identifier : AIDSLINE MED/95116044; Klaus BD
Counting the cost of HIV/AIDS prevention [interview]: Occup Health (Lond). 1994 Nov;46(11):368. Unique Identifier : AIDSLINE MED/95116084; Nakajima H
Visual changes in human immuno-deficiency virus infection.: Optom Vis Sci. 1994 Sep;71(9):557-61. Unique Identifier : AIDSLINE MED/95116113; Kozak LC; Bullimore MA; VA Medical Center, Optometry Section, Newington, Connecticut.; BACKGROUND. Many Human Immuno-Deficiency Virus (HIV) patients develop ocular involvement during the course of the disease, including HIV retinopathy and cytomegalovirus ( CMV ) retinitis. It is well established that contrast se
Epstein-Barr virus-infected marmoset cells do not form lymphomas in mice with severe combined immunodeficiency.: Pediatr Res. 1994 Oct;36(4):456-60. Unique Identifier : AIDSLINE MED/95116208; Katz BZ; Salimi B; Saini U; McNamara JG; Eisen R; Department of Pediatrics, Yale University School of Medicine, New; Haven, Connecticut 06510.; EBV has been associated with several malignancies in humans. EBV can also infect marmoset B lymphocytes, which, as opposed to human B cells, are permissive for lytic Epstein-Barr viral replication. Mice with a severe combined immunodeficiency phenotype (SCID mice) are extremely susceptible to EBV-induced lymphomagenes
Elimination of endogenous aberrant kappa chain transcripts from sp2/0-derived hybridoma cells by specific ribozyme cleavage: utility in genetic therapy of HIV-1 infections.: Nucleic Acids Res. 1994 Dec 11;22(24):5433-8. Unique Identifier : AIDSLINE MED/95116337; Duan L; Pomerantz RJ; Dorrance H. Hamilton Laboratories, Department of Medicine,; Jefferson Medical College, Thomas Jefferson University,; Philadelphia, PA 19107.; The pooled degenerate-primer polymerase chain reaction (PCR) technology is now widely used in the amplification and cloning of murine hybridoma-specific immunoglobulin gene cDNAs. The design of primers is mainly based on the highly conserved 5 terminus of immunoglobulin gene variable regions and the constant region i
Sexuality. A sensitive question.: Nurs Times. 1994 Dec 21-1995 Jan 3;90(51):31-2. Unique Identifier : AIDSLINE MED/95116369; Taylor I; Robertson A
Cytomegalovirus retinitis in persons with AIDS. Selecting therapy for a sight-threatening disease.: Postgrad Med. 1995 Jan;97(1):109-13, 117-8. Unique Identifier : AIDSLINE MED/95116414; Balfour HH Jr; Department of Laboratory Medicine and Pathology, University of; Minnesota Medical School, Minneapolis.; Almost one third of persons with AIDS acquire retinitis caused by the opportunistic cytomegalovirus ( CMV ). Both ganciclovir and foscarnet have been approved for treatment of CMV retinitis and are equally effective. However, t
Anti-human immunodeficiency virus 1 (HIV-1) activities of 3-deazaadenosine analogs: increased potency against 3'-azido-3'-deoxythymidine-resistant HIV-1 strains.: Proc Natl Acad Sci U S A. 1995 Jan 3;92(1):215-9. Unique Identifier : AIDSLINE MED/95116528; Mayers DL; Mikovits JA; Joshi B; Hewlett IK; Estrada JS; Wolfe AD; Garcia GE; Doctor BP; Burke DS; Gordon RK; et al; Walter Reed Army Institute of Research, Washington, DC; 20307-5100.; 3-Deazaadenosine (DZA), 3-deaza-(+/-)-aristeromycin (DZAri), and 3-deazaneplanocin A (DZNep) are powerful modulators of cellular processes. When tested against H9 cells infected acutely with two different strains of human immunodeficiency virus 1 (HIV-1) and in the chronically infected monocytoid cell lines U1 and THP
Human immunodeficiency virus (HIV) antigens: structure and serology of multivalent human mucin MUC1-HIV V3 chimeric proteins.: Proc Natl Acad Sci U S A. 1995 Jan 3;92(1):315-9. Unique Identifier : AIDSLINE MED/95116549; Fontenot JD; Gatewood JM; Mariappan SV; Pau CP; Parekh BS; George JR; Gupta G; Life Sciences Division, Los Alamos National Laboratory, NM 87545.; Molecular modeling and two-dimensional NMR techniques enable us to identify structural features in the third variable region (V3) loop of the human immunodeficiency virus (HIV) surface glycoprotein gp120, in particular the principal neutralizing determinant (PND), that remain conserved despite the sequence variation.
Synthesis of some new 1,6-dihydro-3-substituted 6-spiro-(9'-fluorene)-1,2,4-triazin-5-(4H)-ones as potential anti HIV and anticancer drugs.: Pharmazie. 1994 Oct;49(10):729-33. Unique Identifier : AIDSLINE MED/95116609; Abdel-Rahman RM; Seada M; Fawzy M; el-Baz I; Department of Chemistry, Faculty of Education, Ain Shams; University, Roxy, Cairo, Egypt.; 1,6-Dihydro-3(2H)-thioxo-6-spiro-(9 -fluorene)-1,2,4-triazin 5(4H)-one (1) has been used to synthesize several analogous compounds via nucleophilic substitution reactions. Spectroscopic data are given in support of the proposed structures. Some of the new products possessed good anti HIV and anticancer activities.
[Medical interns and AIDS: perceptions and attitudes in 3 French regions]: Rev Epidemiol Sante Publique. 1994;42(6):548-56. Unique Identifier : AIDSLINE MED/95116680; Guillemot D; Hayward RA; Jayle D; Mistralet L; Clavel T; Meunier C; Shapiro MF; INSERM-Unite 21, Villejuif, France.; This study has been conducted to clarify certain issues regarding residency training with regard to acquired immunodeficiency syndrome (AIDS). The objective was to evaluate resident physicians experiences in, and attitudes toward, the care of persons with AIDS in France . The desig
Flow cytometric analysis of bovine CD4 and CD8 lymphocytes: influence of blood sampling and processing methods.: Res Vet Sci. 1994 Sep;57(2):163-71. Unique Identifier : AIDSLINE MED/95116717; Abella N; Schelcher F; Delverdier M; Concordet D; Valarcher JF; Espinasse J; Cabanie P; Service d'Anatomie Pathologique, Ecole Nationale Veterinaire,; Toulouse, France.; Technical information to facilitate bovine blood treatment for optimum lymphocyte flow cytometry analysis is reported. Murine monoclonal antibodies CC8 and CC63 were used to identify phenotypes corresponding to bovine CD4 T cells and CD8 T cells. Blood samples collected in acid citrate dextrose (ACD) enhanced leucocyt
Effect of 3'azido-2',3'-deoxythymidine (AZT) on experimental feline immunodeficiency virus infection in domestic cats.: Res Vet Sci. 1994 Sep;57(2):220-4. Unique Identifier : AIDSLINE MED/95116725; Smyth NR; Bennett M; Gaskell RM; McCracken CM; Hart CA; Howe JL; Department of Veterinary Clinical Science, University of; Liverpool.; The compound 3 azido-2 ,3 -deoxythymidine ( AZT ) inhibits the replication of feline immunodeficiency virus (FIV) in cell culture, and treatment with the compound has been reported to induce some clinical improvement in some cases of feline FIV infectio
[Epidemiological and clinical development of HIV+ patients followed by the Lausanne University Hospital Center from 1982 to 1992]: Rev Med Suisse Romande. 1994 Dec;114(12):1067-74. Unique Identifier : AIDSLINE MED/95116788; Beck C; Chave JP; Glauser MP; Departement de medecine interne, CHUV, Lausanne.
Nursing's haven for HIV+ patients.: RN. 1994 Dec;57(12):55-7. Unique Identifier : AIDSLINE MED/95116861; Laxson LB
Try this drug when AIDS-related diarrhea won't quit.: RN. 1994 Dec;57(12):71. Unique Identifier : AIDSLINE MED/95116864
Dangerous sex. New signs of risk taking prompt rethinking about AIDS prevention [news]: Sci Am. 1995 Feb;272(2):10, 12. Unique Identifier : AIDSLINE MED/95116914; Yam P
The relationship of alcohol use to sexual activity in a U.S. national sample.: Soc Sci Med. 1994 Dec;39(11):1527-35. Unique Identifier : AIDSLINE MED/95116947; Leigh BC; Temple MT; Trocki KF; Alcohol Research Group, Medical Research Institute of San; Francisco, Berkeley, CA.; Recent reports have indicated that the use of alcohol is related to sexual behavior (such as unprotected intercourse) that is high-risk for HIV infection. However, most of these studies have collected data from convenience samples, using measures of varying specificity. This paper describes a study designed to investi
Psychological well-being of gay men with AIDS: contribution of positive and negative illness-related network interactions to depressive mood.: Soc Sci Med. 1994 Dec;39(11):1555-63. Unique Identifier : AIDSLINE MED/95116950; Siegel K; Raveis VH; Karus D; Memorial Sloan-Kettering Cancer Center, New York, NY 10021.; While the positive functions of social network interactions in ameliorating the effects of life stress are widely documented and acknowledged, a growing body of research investigations has demonstrated that social relationships can concurrently be a source of stress and that actions intended to be supportive may inste
HIV prevention education for lesbians and bisexual women: a cultural analysis of a community intervention.: Soc Sci Med. 1994 Dec;39(11):1565-78. Unique Identifier : AIDSLINE MED/95116951; Stevens PE; Department of Mental Health, Community & Administrative Nursing,; School of Nursing, University of California, San Francisco.; AIDS is increasing almost four times as fast among women, yet lesbians and bisexual women are among the least studied, least understood and most elusive populations affected by the AIDS epidemic. This paper reports the results of community-level HIV prevention research designed: (a) to examine the knowledge, perceptio
Behavioural change amongst drug injectors in Scottish prisons.: Soc Sci Med. 1994 Dec;39(11):1585-6. Unique Identifier : AIDSLINE MED/95116952; Shewan D; Gemmell M; Davies JB; Addiction Research Group, University of Strathclyde, Glasgow,; Scotland.; A study of injecting behaviour amongst a purposive sample of drug-users in Scottish prisons found that 32% reported injecting prior to current sentence. The percentage of these who were injecting during their current prison sentence (i.e. inside the prison) had fallen to 11%. Of those who were injecting prior to impri
Appearance of drug-resistant tuberculosis in rural Tennessee.: South Med J. 1995 Jan;88(1):60-4. Unique Identifier : AIDSLINE MED/95116960; Mehta J; Diaz C; Guha B; Harvill L; Krishnaswamy G; Department of Internal Medicine, James H. Quillen College of; Medicine, East Tennessee State University, Johnson City; 37614-0622.; Drug-resistant tuberculosis (DRTB) is a growing national health concern in both urban populations and rural areas and is exacerbated by the growing epidemic of human immunodeficiency virus (HIV) infection. Between 1989 and 1992, 7 cases of DRTB (5 with multidrug-resistance) were diagnosed in an eight-county region of
Thrombotic thrombocytopenic purpura and HIV infection [see comments]: South Med J. 1995 Jan;88(1):82-6. Unique Identifier : AIDSLINE MED/95116964; Chu QD; Medeiros LJ; Fisher AE; Chaquette RF; Crowley JP; Department of Medicine, Rhode Island Hospital, Providence 02903.; We report on a man who was HIV-seropositive and who was initially admitted following multiple episodes of syncope. He gradually developed fulminant thrombotic thrombocytopenic purpura (TTP). Twenty-one patients with TTP who were HIV-positive have been reported previously. Of these 22 patients, all treated with plasmap
HIV and pulmonary hypertension [letter; comment]: South Med J. 1995 Jan;88(1):94-5. Unique Identifier : AIDSLINE MED/95116968; Guerin JM; Vidal P
Characterization of the cytopathic effect of Haemophilus ducreyi.: Sex Transm Dis. 1994 Sep-Oct;21(5):247-57. Unique Identifier : AIDSLINE MED/95116989; Hollyer TT; DeGagne PA; Alfa MJ; Department of Medical Microbiology, University of Manitoba,; Winnipeg, Canada.; BACKGROUND AND OBJECTIVES: Haemophilus ducreyi is the etiologic agent of chancroid, which is a genital ulcer disease that increases the risk of acquiring and transmitting HIV. The pathogenesis of H. ducreyi is not well understood. GOAL OF THIS STUDY: The goal of this study was to use a quantitative tetrazolium-based X
Incidence and risk factors for acquisition of sexually transmitted diseases in heterosexuals with multiple partners.: Sex Transm Dis. 1994 Sep-Oct;21(5):258-67. Unique Identifier : AIDSLINE MED/95116990; Prins M; Hooykaas C; Coutinho RA; van Doornum GJ; van den Hoek AJ; Municipal Health Service, Department of Public Health and; Environment, Amsterdam, The Netherlands.; BACKGROUND AND OBJECTIVES: The incidence of four STDs that are mainly transmitted during vaginal intercourse, and risk factors for acquisition during follow-up were studied in a cohort of heterosexuals with multiple partners in Amsterdam, the Netherlands . These heterosexuals w
Seroepidemiological studies of Haemophilus ducreyi infection in Ethiopian women.: Sex Transm Dis. 1994 Sep-Oct;21(5):280-8. Unique Identifier : AIDSLINE MED/95116993; Duncan ME; Roggen E; Tibaux G; Pelzer A; Mehari L; Piot P; Department of Medical Microbiology, University of Edinburgh,; Scotland.; BACKGROUND AND OBJECTIVES: To measure prevalence of anti-Haemophilus ducreyi antibodies in sera from Ethiopian female attendees, and to determine significant socioeconomic associations. STUDY DESIGN: A modified ELISA immunoassay was used to test sera of 1,831 Ethiopian women attending gynecological, obstetric, and fam
Prevalence of HIV seropositivity among inner-city adolescents in 1988 and 1992.: Tex Med. 1994 Dec;90(12):48-51. Unique Identifier : AIDSLINE MED/95117059; Snabes MC; Weinman ML; Smith PB; Baylor College of Medicine, Department of Obstetrics/Gynecology,; Houston, TX 77030.; The purpose of this study was to document the change in prevalence of human immunodeficiency virus (HIV) infection among sexually active minority teens at a primary and reproductive teen health clinic. Both new and current patients were sampled in a seroprevalence study in 1988 and again in 1992. None of the 1200 adol
Persistent low plasma levels of HIV-1 in patients on AZT therapy and its implications [letter]: Therapie. 1994 Mar-Apr;49(2):146-7. Unique Identifier : AIDSLINE MED/95117074; Camsonne R; Bustany P; Bigot MC; Pottier D; Moulin MA
[Crystalluria induced by sulfadiazine in an AIDS patient (letter)]: Therapie. 1994 Mar-Apr;49(2):154-5. Unique Identifier : AIDSLINE MED/95117083; Bressollette L; Carlhant D; Bellein V; Morand C; Mottier D; Riche C
[Asymptomatic sexually transmitted infections among HIV-tested persons]: Ugeskr Laeger. 1994 Nov 21;156(47):7048-9. Unique Identifier : AIDSLINE MED/95117154; Munkvad S; Worm AM; Smith E; Osterlind AL; Dermato-venerologisk afdeling A, Bispebjerg Hospital, Kobenhavn.; We have prospectively determined the frequency of asymptomatic sexually transmitted diseases (STD) among patients seeking an HIV-test. In 246 patients, we observed 32 cases (13%) of asymptomatic STD, predominantly infections caused by Chlamydia trachomatis or human Papillomavirus. STD screening is of significance amon
Genitourinary manifestations of the acquired immunodeficiency syndrome.: Urology. 1995 Jan;45(1):13-27. Unique Identifier : AIDSLINE MED/95117206; Kwan DJ; Lowe FC; Department of Urology, St. Luke's-Roosevelt Hospital Center, New; York, New York.; As the number of HIV-1 infected individuals and AIDS patients continues to increase, more cases involving the genitourinary tract will be encountered. Often, genitourinary manifestations will be the initial presentation of AIDS. Proper diagnosis will require awareness and a high index of suspicion. In addition to rout
Mycobacterium avium-intracellulare and acute abdominal pain.: West J Med. 1994 Oct;161(4):415-7. Unique Identifier : AIDSLINE MED/95117308; Boyle EM Jr; Stephens K Jr; Pohlman TH; Department of Surgery, Harborview Medical Center, University of; Washington School of Medicine, Seattle.
The Swiss HIV Cohort Study: rationale, organization and selected baseline characteristics.: Soz Praventivmed. 1994;39(6):387-94. Unique Identifier : AIDSLINE MED/95117379; Ledergerber B; von Overbeck J; Egger M; Luthy R; Department of Medicine, University Hospital Zurich.; OBJECTIVES: This paper describes the rationale and design features of the Swiss HIV Cohort Study (SHCS) and the baseline characteristics of participants enrolled up to March 31st 1993. The objectives include epidemiological, clinical and laboratory research. DESIGN: The SHCS is a prospective cohort study of HIV infect
Application of polymerase chain reaction (PCR) to the microscopically identified cells on the slides: evaluation of specificity and sensitivity of single cell PCR.: Acta Med Okayama. 1994 Aug;48(4):189-93. Unique Identifier : AIDSLINE MED/95117529; Teramoto N; Tonoyama Y; Akagi T; Sarker AB; Yoshino T; Yamadori I; Takahashi K; Second Department of Pathology, Okayama University Medical; School, Japan.; The sensitivity and specificity of single cell polymerase chain reaction (PCR) were studied. Its high sensitivity enabled detection of a single-copy gene, such as human T-lymphotropic virus type I genome in paraffin sections. The rate of obtaining positive signals with this method was affected by the number of copies
Human immunodeficiency virus type 1-associated CD4 downmodulation.: Adv Virus Res. 1994;44:203-66. Unique Identifier : AIDSLINE MED/95117632; Geleziunas R; Bour S; Wainberg MA; Department of Microbiology and Immunology, McGill University,; Montreal, Quebec, Canada.
Estimation of current human immunodeficiency virus incidence rates from a cross-sectional survey using early diagnostic tests.: Am J Epidemiol. 1995 Jan 15;141(2):166-72. Unique Identifier : AIDSLINE MED/95117734; Brookmeyer R; Quinn TC; Department of Biostatistics, School of Hygiene and Public Health,; Johns Hopkins University, Baltimore, MD 21205.; In sharp contrast to the considerable worldwide epidemiologic data available on acquired immunodeficiency syndrome incidence and human immunodeficiency virus (HIV) seroprevalence, there is relatively little information about current levels of HIV incidence rates. The authors suggest a novel approach for estimating cur
Re: Bacterial pneumonia in adult populations with human immunodeficiency virus (HIV) infection [letter; comment] [published erratum appears in Am J Epidemiol 1995 Apr 1;141(7):697]: Am J Epidemiol. 1995 Jan 15;141(2):176-7. Unique Identifier : AIDSLINE MED/95117737; Clark R; Kissinger P
Cost analysis and HIV prevention interventions.: Am Psychol. 1994 Dec;49(12):1088-9. Unique Identifier : AIDSLINE MED/95117997; Holtgrave DR; Office of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, GA.
NIDA's HIV prevention programs.: Am Psychol. 1994 Dec;49(12):1089-90. Unique Identifier : AIDSLINE MED/95117998; Needle RH; Brown BS; Coyle SL; Weissman G; National Institute on Drug Abuse, Rockville, MD.
CDC behavioral interventions.: Am Psychol. 1994 Dec;49(12):1090-2. Unique Identifier : AIDSLINE MED/95117999; Cotton D; Higgins D; Person B; Darrow W; Behavioral and Prevention Research Branch, Centers for Disease; Control and Prevention, Atlanta, GA.
On the new call for HIV prevention research.: Am Psychol. 1994 Dec;49(12):1092-3. Unique Identifier : AIDSLINE MED/95118000; Truax SR; California Department of Health Services, Office of AIDS/HIV; Testing Section, Sacramento.
Adenosine stimulates DNA fragmentation in human thymocytes by Ca(2+)-mediated mechanisms.: Biochem J. 1994 Dec 15;304 ( Pt 3):877-85. Unique Identifier : AIDSLINE MED/95118307; Szondy Z; Department of Biochemistry, University Medical School of; Debrecen, Hungary.; Incubation of human thymocytes with an optimum concentration of adenosine and its receptor site agonist, 2-chloroadenosine, induced increases in intracellular cyclic AMP (cAMP) (from a resting 0.6 +/- 0.1 to 4.1 +/- 0.2 pmol/10(7) cells within 5 min) and Ca2+ (from the resting 85 +/- 7 nM to a peak of 210 +/- 25 nM) l
A novel approach to protein-protein interaction: complex formation between the p53 tumor suppressor and the HIV Tat proteins.: Biochem Biophys Res Commun. 1995 Jan 5;206(1):326-34. Unique Identifier : AIDSLINE MED/95118356; Longo F; Marchetti MA; Castagnoli L; Battaglia PA; Gigliani F; Dipartimento di Biopatologia Umana Sezione di Biologia Cellulare; Universita di Roma La Sapienza, Rome, Italy.; By using a novel genetic approach, based on the properties of lambda cl repressor, we demonstrate that the HIV-1 Tat protein specifically interacts with the human p53 protein via the p53 O2 dimerization domain. By random and site-specific mutagenesis, we also identify the residues in Tat and O2 peptides which are invo
Chronic ethanol consumption prior to retrovirus infection alters cytokine production by thymocytes during murine AIDS.: Alcohol. 1994 Sep-Oct;11(5):361-5. Unique Identifier : AIDSLINE MED/95118512; Wang Y; Watson RR; Nutritional Sciences Program, University of Arizona, Tucson; 85724.; Chronic ethanol (EtOH) consumption may be a cofactor in the development of acquired immune deficiency syndrome (AIDS). As the thymus is an unique site for T cell maturation, we investigated whether thymocytes from EtOH consuming mice were more predisposed to aberrant cytokine production due to retrovirus infection. Ad
Indirect costs of HIV/AIDS mortality in Canada.: AIDS. 1994 Oct;8(10):F7-11. Unique Identifier : AIDSLINE MED/95118526; Hanvelt RA; Ruedy NS; Hogg RS; Strathdee S; Montaner JS; O'Shaughnessy MV; Schechter MT; British Columbia Centre for Excellence in HIV/AIDS, St Paul's; Hospital, Vancouver, Canada.; OBJECTIVE: To estimate and compare the societal impact of HIV infection and AIDS with other selected causes of male mortality in terms of the indirect costs of future production lost. DESIGN: Descriptive, population-based economic evaluation study. PATIENTS: All men aged 25-64 years for whom HIV/AIDS or another select
Prevention indicators for evaluating the progress of national AIDS programmes [editorial]: AIDS. 1994 Oct;8(10):1359-69. Unique Identifier : AIDSLINE MED/95118527; Mertens T; Carael M; Sato P; Cleland J; Ward H; Smith GD
Prevention of HIV infection [editorial]: AIDS. 1994 Oct;8(10):1371-89. Unique Identifier : AIDSLINE MED/95118528; Choi KH; Coates TJ
T-cell proliferation to subinfectious SIV correlates with lack of infection after challenge of macaques.: AIDS. 1994 Oct;8(10):1391-5. Unique Identifier : AIDSLINE MED/95118529; Clerici M; Clark EA; Polacino P; Axberg I; Kuller L; Casey NI; Morton WR; Shearer GM; Benveniste RE; Experimental Immunology Branch, National Cancer Institute,; Bethesda, Maryland.; OBJECTIVES: To analyze correlates of protection in macaques exposed to SIV. METHODS: Peripheral blood mononuclear cells (PBMC) from macaques inoculated intrarectally with various dilutions of SIV were examined for their in vitro proliferative response to SIV envelope peptides and generation of SIV-specific antibodies.
Staphylococcal superantigens activate HIV-1 replication in naturally infected monocytes.: AIDS. 1994 Oct;8(10):1397-404. Unique Identifier : AIDSLINE MED/95118530; Goujard C; Wallon C; Rudent A; Boue F; Barre-Sinoussi F; Delfraissy JF; INSERM U131, Department of Medicine, Antoine Beclere Hospital,; Clamart, France.; OBJECTIVES: To study the effects of microbial superantigens, Staphylococcal exotoxins (SE), on HIV replication in monocytes following binding to and signalling through major histocompatibility complex (MHC) class II molecules. METHODS: We investigated the effects of SE on HIV replication and monokine production in thr
Genotypic subtypes of HIV-1 in Cameroon.: AIDS. 1994 Oct;8(10):1405-12. Unique Identifier : AIDSLINE GENBANK/X80454; Nkengasong JN; Janssens W; Heyndrickx L; Fransen K; Ndumbe PM; Motte J; Leonaers A; Ngolle M; Ayuk J; Piot P; et al; Department of Infection and Immunity, Institute of Tropical; Medicine, Antwerp, Belgium.; OBJECTIVE: The only two HIV-1 strains (ANT70 and MVP5180) reported to date from Cameroon are members of the outlier clade (group O). In this study, we assessed the prevalence of group O viruses and other HIV-1 subtypes in Cameroon. DESIGN: A phylogenetic analysis of 18 HIV-1 stra
Interleukin-12 enhances antigen-specific proliferation of peripheral blood mononuclear cells from HIV-positive and negative donors in response to Mycobacterium avium.: AIDS. 1994 Oct;8(10):1413-9. Unique Identifier : AIDSLINE MED/95118532; Newman GW; Guarnaccia JR; Vance EA 3rd; Wu JY; Remold HG; Kazanjian PH Jr; Department of Rheumatology/Immunology, Brigham & Women's; Hospital/Harvard Medical School, Boston 02115.; OBJECTIVE: To determine if the addition of recombinant (r) human interleukin (IL)-12 enhances in vitro proliferative responses to Mycobacterium avium of peripheral blood mononuclear cells (PBMC) from HIV-positive donors with CD4 cell counts
HIV-1 immunogen induction of HIV-1-specific delayed-type hypersensitivity: results of a double-blind, adjuvant-controlled, dose-ranging trial.: AIDS. 1994 Oct;8(10):1429-35. Unique Identifier : AIDSLINE MED/95118534; Turner JL; Trauger RJ; Daigle AE; Carlo DJ; Graduate Hospital, Philadelphia, Pennsylvania 19146.; OBJECTIVE: To investigate the capacity of an HIV-1 immunogen to induce or augment HIV-1-specific delayed-type hypersensitivity (DTH) over a range of doses in asymptomatic HIV-1-seropositive adults. DESIGN: A single center, double-blind, adjuvant-controlled, dose-ranging trial involving 48 HIV-1-seropositive asymptomat
Community-acquired Pseudomonas aeruginosa pneumonia in patients with HIV infection.: AIDS. 1994 Oct;8(10):1437-41. Unique Identifier : AIDSLINE MED/95118535; Schuster MG; Norris AH; Division of Infectious Diseases, University of Pennsylvania; Medical Center, Philadelphia.; OBJECTIVE: To describe the clinical and radiographic presentation, risk factors, response to therapy and outcome of 16 patients with HIV infection and pulmonary infections caused by Pseudomonas aeruginosa. DESIGN: Retrospective review of medical records. SETTING: An academic tertiary-care hospital. PATIENTS: Sixteen p
HIV-1 incidence determined retrospectively among drug users in Bangkok, Thailand [see comments]: AIDS. 1994 Oct;8(10):1443-50. Unique Identifier : AIDSLINE MED/95118536; Kitayaporn D; Uneklabh C; Weniger BG; Lohsomboon P; Kaewkungwal J; Morgan WM; Uneklabh T; HIV/AIDS Collaboration, Nonthaburi, Thailand.; OBJECTIVE: To measure trends in the incidence of HIV-1 infection among drug users in treatment at Thailand s largest drug detoxification unit. DESIGN: A retrospective cohort was established using computed, existing HIV-1 test results of 26,396 inpatients and outpatients admitted for 47,907 drug detoxification treatmen
Mother-to-child transmission of HIV-1 in Congo, central Africa. Congolese Research Group on Mother-to-Child Transmission of HIV [see comments]: AIDS. 1994 Oct;8(10):1451-6. Unique Identifier : AIDSLINE MED/95118537; Lallemant M; Le Coeur S; Samba L; Cheynier D; M'Pele P; Nzingoula S; Essex M; Department of Cancer Biology, Harvard School of Public Health,; Boston, Massachusetts 02115.; OBJECTIVE: To assess the risk of mother-to-child transmission of HIV-1 in a central African population and to study maternal factors associated with perinatal transmission. DESIGN: Prospective cohort study of infants born to HIV-1-positive women and controls born to HIV-1-negative women enrolled sequentially in two pr
Mortality of intravenous drug users living in Milan, Italy: role of HIV-1 infection. COMCAT Study Group.: AIDS. 1994 Oct;8(10):1457-63. Unique Identifier : AIDSLINE MED/95118538; Galli M; Musicco M; Clinic of Infectious Disease, Luigi Sacco Hospital, Milan, Italy.; OBJECTIVES: To study the trend in mortality from 1980 to 1991 in a cohort of 2432 intravenous drug users (IVDU) enrolled between 1 November 1980 and 31 December 1988. In addition, to evaluate the impact of HIV-1 infection on mortality. DESIGN: The vital status of people enrolled in the cohort was ascertained at regist
HIV infection among non-injecting drug users entering drug treatment, United States, 1989-1992. Field Services Branch.: AIDS. 1994 Oct;8(10):1465-9. Unique Identifier : AIDSLINE MED/95118539; Lehman JS; Allen DM; Green TA; Onorato IM; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, Georgia 30333.; OBJECTIVE: To describe HIV seroprevalence among non-injecting drug users (non-IDU) entering sentinel drug treatment centers in the United States . DESIGN: Anonymous, blinded (unlinked) HIV seroprevalence surveys. SETTING: Sixty-eight sentinel drug treatment centers in 37 United States m
Increasing age is associated with faster progression to neoplasms but not opportunistic infections in HIV-infected homosexual men.: AIDS. 1994 Oct;8(10):1471-5. Unique Identifier : AIDSLINE MED/95118540; Veugelers PJ; Strathdee SA; Tindall B; Page KA; Moss AR; Schechter MT; Montaner JS; van Griensven GJ; Municipal Health Service, Department of Public Health, Amsterdam,; The Netherlands.; OBJECTIVE: To characterize the associations of age and progression rates to AIDS-defining neoplasms and opportunistic infections (OI) in HIV-infected homosexual men. METHODS: Data from 407 homosexual men with documented dates of HIV seroconversion participating in cohort studies from four geographic locations were mer
Prevalence of HIV-1 infection in urban, semi-urban and rural areas in Arusha region, Tanzania.: AIDS. 1994 Oct;8(10):1477-81. Unique Identifier : AIDSLINE MED/95118541; Mnyika KS; Klepp KI; Kvale G; Nilssen S; Kissila PE; Ole-King'ori N; Department of Epidemiology and Biostatistics, Muhimbili; University College of Health Sciences, Dar-es-Salaam, Tanzania.; OBJECTIVE: To estimate HIV-1 prevalence among the adult population in the Arusha region, northern Tanzania . DESIGN: Cross-sectional study. METHODS: Clusters of 10 households were randomly selected from urban, semi-urban and rural areas in the Arusha region. Informed verbal consen
Family support for heterosexual partners in HIV-serodiscordant couples.: AIDS. 1994 Oct;8(10):1483-7. Unique Identifier : AIDSLINE MED/95118542; Foley M; Skurnick JH; Kennedy CA; Valentin R; Louria DB; Texas Department of Health, Austin.; OBJECTIVE: To ascertain the extent of family member support to heterosexual HIV-serodiscordant couples, and to identify associated sociodemographic and clinical characteristics. DESIGN: Discordant couples enrolled in a cohort study of heterosexual HIV transmission were interviewed with structured questionnaires to obt
Surveillance of AIDS-defining conditions in the United States. Adult/Adolescent Spectrum of HIV Disease Project Group.: AIDS. 1994 Oct;8(10):1489-93. Unique Identifier : AIDSLINE MED/95118543; Jones JL; Hanson DL; Chu SY; Fleming PL; Hu DJ; Ward JW; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, Georgia 30333.; OBJECTIVE: To examine the reporting of AIDS-defining illnesses using two national surveillance systems. METHODS: Comparison of AIDS indicator diseases reported to the national AIDS reporting system (ARS) for AIDS cases diagnosed from January 1990-December 1992 among individuals aged > 13 years in 10 metropolitan areas
Reasons for the wide variation in reported rates of mother-to-child transmission of HIV-1 [editorial; comment] [see comments]: AIDS. 1994 Oct;8(10):1495-7. Unique Identifier : AIDSLINE MED/95118544; Ryder RW; Behets F
The epidemiology of HIV infection among injecting drug users and other risk populations in Thailand [editorial; comment]: AIDS. 1994 Oct;8(10):1499-500. Unique Identifier : AIDSLINE MED/95118545; Nelson KE
Human T-cell leukaemia virus-I/II infection in Equatorial Guinea [letter]: AIDS. 1994 Oct;8(10):1501-3. Unique Identifier : AIDSLINE MED/95118546; Vallejo A; Benito A; Varela JM; Casado C; Roche J; Alvar J; Garcia-Saiz A
Influenza immunization of HIV-1-infected patients does not increase HIV-1 viral load [letter]: AIDS. 1994 Oct;8(10):1503-4. Unique Identifier : AIDSLINE MED/95118547; Yerly S; Wunderli W; Wyler CA; Kaiser L; Hirschel B; Suter S; Perrin LH; Siegrist CA
HIV-1 Tat induces cytokine synthesis by uninfected mononuclear cells [letter]: AIDS. 1994 Oct;8(10):1504-6. Unique Identifier : AIDSLINE MED/95118548; Rautonen N; Rautonen J; Martin NL; Wara DW
Resistance to trimethoprim-sulfamethoxazole and sensitivity to pentamidine therapy in an AIDS patient with hepatosplenic pneumocytosis [letter]: AIDS. 1994 Oct;8(10):1506-7. Unique Identifier : AIDSLINE MED/95118549; Lecuit M; Livartowski J; Vons C; Goujard C; Lemaigre G; Delfraissy JF; Dormont J
Anal cancer in patients with HIV infection: a report of two cases without evidence of immunological dysfunction [letter]: AIDS. 1994 Oct;8(10):1507-8. Unique Identifier : AIDSLINE MED/95118550; Nasti G; Santarossa S; Vaccher E; Serraino D; Carbone A; Tirelli U
Autoantibody-mediated platelet phagocytosis in SIV-infected macaques [letter]: AIDS. 1994 Oct;8(10):1509. Unique Identifier : AIDSLINE MED/95118551; Dittmer U; Coulibaly C; Sauermann U; Stahl-Hennig C; Petry H; Hunsmann G; Kaup FJ
The sharing of injecting paraphernalia among illicit drug users [letter]: AIDS. 1994 Oct;8(10):1509-11. Unique Identifier : AIDSLINE MED/95118552; Power R; Hunter GM; Jones SG; Donoghoe MC
Traditional healers in AIDS control [letter]: AIDS. 1994 Oct;8(10):1511-2. Unique Identifier : AIDSLINE MED/95118553; Berger RA; Porter L; Mekisini G; Courtright P
Infection with HIV, a risk factor for epidemic dysentery? A case-control study from Zambia [letter]: AIDS. 1994 Oct;8(10):1512-3. Unique Identifier : AIDSLINE MED/95118554; van Oosterhout JJ; van der Hoek W
Hemi-nested quantitative competitive PCR of HIV-1.: Biotechniques. 1994 Sep;17(3):440-2. Unique Identifier : AIDSLINE MED/95118626; Zimmermann K; Schogl D; Mannhalter JW; Department of Immunological Research, Immuno AG, Vienna, Austria.
A comparison of HIV risk between women and men who inject drugs.: AIDS Educ Prev. 1994 Oct;6(5):379-89. Unique Identifier : AIDSLINE MED/95118726; Dwyer R; Richardson D; Ross MW; Wodak A; Miller ME; Gold J; Kirketon Road Centre, Sydney Hospital, Australia.; Although there is growing evidence of differences between women and men who inject drugs (IDUs) in terms of level of risk for HIV infection, very little research has been conducted specifically addressing the risk practices of women IDUs. This study formed part of a national study of HIV infection risks in IDUs and th
HIV-infected women and sexual risk reduction: the relevance of existing models of behavior change.: AIDS Educ Prev. 1994 Oct;6(5):390-402. Unique Identifier : AIDSLINE MED/95118727; Kline A; VanLandingham M; New Jersey Department of Health, Trenton.; This article utilizes constructs of the AIDS Risk Reduction Model (ARRM) to examine condom use in a sample of 215 HIV-infected women in New Jersey. We find evidence that processes affecting condom use in HIV-infected individuals are similar to those found in HIV-negative individuals. Results suggest that partner-relat
Self-disclosure of HIV infection to sexual partners after repeated counseling.: AIDS Educ Prev. 1994 Oct;6(5):403-11. Unique Identifier : AIDSLINE MED/95118728; Perry SW; Card CA; Moffatt M Jr; Ashman T; Fishman B; Jacobsberg LB; HIV Clinical Research Program, Cornell University Medical; College, New York, NY 10021.; This study, with the objective of examining voluntary self-disclosure of HIV infection after repeated counseling, was conducted in a private setting, and designed to operate in conjunction with HIV testing. Counseling was provided at entry, and then at 3 months, 6 months, and every six months thereafter. The study was
Evaluation of a theory-based HIV prevention intervention for college students.: AIDS Educ Prev. 1994 Oct;6(5):412-24. Unique Identifier : AIDSLINE MED/95118729; Basen-Engquist K; Center for Health Promotion Research and Development, School of; Public Health, University of Texas Health Science Center at; Houston, 77225.; This study tested the effectiveness of a workshop for college students designed to increase HIV-preventive behavior by increasing participants self-efficacy concerning HIV-preventive behavior. The Safer Sex Efficacy Workshop (SSE workshop) was compared with a lecture on HIV (HIV lecture) and a lecture on an unrelated
Cognitive-behavioral group intervention to assist substance-dependent adolescents in lowering HIV infection risk.: AIDS Educ Prev. 1994 Oct;6(5):425-35. Unique Identifier : AIDSLINE MED/95118730; St. Lawrence JS; Jefferson KW; Banks PG; Cline TR; Alleyne E; Brasfield TL; Community Health Program, Jackson State University, MS; 39217-0105.; Substance dependent adolescents (N = 19), court referred into a residential drug treatment facility received a five-session HIV risk-reduction intervention that provided risk education, social competency skills (sexual assertion, partner negotiation, and communication skills), technical skills (condom use), and proble
Attitudes and practices of hemophilia care providers involved in HIV risk-reduction counseling.: AIDS Educ Prev. 1994 Oct;6(5):436-45. Unique Identifier : AIDSLINE MED/95118731; Meredith KL; Hannan JA; Green TA; Wiley SD; Division of HIV/AIDS, National Center for Infectious Diseases,; Centers for Disease Control and Prevention, Atlanta, GA 30341.; Hemophilia physicians, nurses, and social workers attending a national conference were asked to complete a questionnaire assessing their attitudes and practices regarding HIV risk-reduction counseling. All of the 150 respondents reported recommending the use of condoms to their clients, but only two-thirds felt comfor
Evaluating multicultural approaches in HIV/AIDS educational material.: AIDS Educ Prev. 1994 Oct;6(5):446-53. Unique Identifier : AIDSLINE MED/95118732; Walters JL; Canady R; Stein T; AIDS Education Project, Michigan State University, East Lansing; 48824.; In recent years health educators have become more aware of the impact of culture on the success of health education programs. This awareness has prompted experimentation with the use of cultural elements in HIV prevention and education efforts. The literature on multicultural education offers little guidance to the he
Evaluation of a thicker condom for use as a prophylactic against HIV transmission.: AIDS Educ Prev. 1994 Oct;6(5):454-8. Unique Identifier : AIDSLINE MED/95118733; Golombok S; Sheldon J; Clinical & Health Psychology Research Centre, City University,; London, England.; In an evaluation of the breakage rate of a thicker condom when used for anal intercourse, one hundred and eight gay men volunteered to use condoms which were 30% thicker than standard condoms. Of the 772 condoms used, 14 broke during anal sex, representing a breakage rate of 1.8%. When one subject was removed from the
Seventh International Conference on AIDS Education. November 13-17, 1993, Chicago, Illinois [news]: AIDS Educ Prev. 1994 Oct;6(5):459-61. Unique Identifier : AIDSLINE MED/95118734
Homologous blood transfusion: the risks and alternatives.: Br J Haematol. 1994 Nov;88(3):451-8. Unique Identifier : AIDSLINE MED/95118818; Williamson L; Division of Transfusion Medicine, University of Cambridge.
Dysplastic haemopoiesis following orthotopic liver transplantation: comparison with similar changes in HIV infection and primary myelodysplasia.: Br J Haematol. 1994 Dec;88(4):685-92. Unique Identifier : AIDSLINE MED/95118862; Clatch RJ; Krigman HR; Peters MG; Zutter MM; Department of Pathology, Washington University School of; Medicine, St. Louis, MO 63110.; To validate scientifically our prior empiric observations that patients develop significant haemopoietic dysplasia following solid organ transplantation, we developed a quantitative lineage-specific scoring system to evaluate dysplastic features of bone marrow aspirates and core biopsies. We used this scoring system t
The development of antiphospholipid antibodies in haemophilia is linked to infection with hepatitis C.: Br J Haematol. 1994 Dec;88(4):845-8. Unique Identifier : AIDSLINE MED/95118883; al-Saeed A; Makris M; Malia RG; Preston FE; Greaves M; Department of Haematology, Royal Hallamshire Hospital, Sheffield.; In haemophilia the presence of antibodies to antiphospholipid has been linked with HIV infection, but other possibilities have not been fully explored and the specificity for various phospholipids not established. In order to investigate further the pathogenesis and clinical significance of these antibodies, we have d
Cis-acting DNA elements and cell type-specific nuclear proteins which may play a role in regulation of mouse CD8 alpha (Lyt-2) gene transcription.: Int Immunol. 1994 Sep;6(9):1307-21. Unique Identifier : AIDSLINE MED/95118927; Lee WH; Banan M; Harriss JV; Hwang I; Woodward E; Youn HJ; Gottlieb PD; Department of Microbiology, University of Texas at Austin 78712.; Fusion of mouse CD8+ class I MHC-restricted T cells with the BW5147 thymoma invariably yields CD8- hybridomas in which RNA transcribed from the CD8 alpha (Lyt-2) gene is undetectable. To determine whether cis-acting DNA sequences may negatively regulate transcription of the Lyt-2 gene in BW5147 cells, one possible exp
cAMP up-regulates IL-4 and IL-5 production from activated CD4+ T cells while decreasing IL-2 release and NF-AT induction.: Int Immunol. 1994 Sep;6(9):1333-43. Unique Identifier : AIDSLINE MED/95118929; Lacour M; Arrighi JF; Muller KM; Carlberg C; Saurat JH; Hauser C; Department of Dermatology, Hopital Cantonal Universitaire de; Geneve, Switzerland.; Seven days after activation with concanavalin A and irradiated spleen cells, murine CD4+ T cells were re-stimulated with ionomycin and phorbol 12-myristate 13-acetate (PMA). IL-2 and IL-4 were determined in the supernatant. When cholera toxin, forskolin together with p
Alternative complement pathway activation by CD4+ T cells of HIV infected individuals: a possible role in AIDS pathogenesis.: Int Immunol. 1994 Sep;6(9):1361-6. Unique Identifier : AIDSLINE MED/95118932; Yefenof E; Magyarlaki T; Fenyo EM; Wahren B; Klein E; Lautenberg Center of Immunology, Hebrew University--Hadassah; Medical School, Jerusalem, Israel.; The mechanisms by which CD4+ T cells are eliminated during HIV infection are poorly understood. We have previously shown that HIV infected cell lines activate and fix C3 via the alternative complement pathway (ACP). In the present study we examined the ability of blood lymphocytes from 40 HIV+ individuals to fix C3. A
Preferential TCR V usage in rat repertoire selection: V alpha 8 imparts both positive thymic selection by and alloreactivity to RT1f.: Int Immunol. 1994 Sep;6(9):1367-73. Unique Identifier : AIDSLINE MED/95118933; Torres-Nagel NE; Herrmann T; Giegerich G; Wonigeit K; Hunig T; Institut fur Virologie und Immunbiologie, Universitat; Wurzburg, Germany.; Using a panel of newly developed mAb to two rat TCR V alpha and four TCR V beta segments, TCR V usage in CD4 and CD8 T cells of eight RT1 congenic strains sharing the LEW background was analyzed by flow cytometry. While no striking effects on V beta 8.2 and 8.5 usage were observed, a 3- to 4-fold over-representation o
Different types of in vivo induced cytolytic T lymphocytes are all LFA-Ihigh and lack CD45 exon 4 (CD45RA) but show distinct CD45RC profiles.: Int Immunol. 1994 Sep;6(9):1375-81. Unique Identifier : AIDSLINE MED/95118934; Hansson J; Ericsson PO; Widegren B; Dohlsten M; Sjogren HO; Hedlund G; Wallenberg Laboratory, Department of Tumor Immunology, University; of Lund, Sweden.; Due to alternate mRNA splicing of exons 4, 5 and 6 (or A, B and C respectively), the CD45 cell surface glycoprotein is structurally heterogeneic in lymphoid cells of different lineage or stage of activation. Previous studies show that in vivo induced allo- and superantigen reactive rat cytolytic T lymphocytes (CTL) pr
Prevention of insulitis and diabetes in beta 2-microglobulin-deficient non-obese diabetic mice.: Int Immunol. 1994 Sep;6(9):1445-9. Unique Identifier : AIDSLINE MED/95118942; Sumida T; Furukawa M; Sakamoto A; Namekawa T; Maeda T; Zijlstra M; Iwamoto I; Koike T; Yoshida S; Tomioka H; et al; Second Department of Internal Medicine, School of Medicine, Chiba; University, Japan.; beta 2-Microglobulin (beta 2m)-deficient non-obese diabetic (NOD) mice were established by crossing beta 2m-deficient 129/Sv mice with NOD mice, and used to examine the possible involvement of MHC class I molecules and CD8+ T cells in the development of insulitis and diabetes. In these mice, MHC class I molecules were
Implication of the common gamma chain of the IL-7 receptor in intrathymic development of pro-T cells.: Int Immunol. 1994 Sep;6(9):1451-4. Unique Identifier : AIDSLINE MED/95118943; Hozumi K; Kondo M; Nozaki H; Kobori A; Nishimura T; Nishikawa S; Sugamura K; Habu S; Department of Immunology, Tokai University School of Medicine,; Isehara, Japan.; The effects of IL-7 on the growth and differentiation of thymocytes were analyzed using murine fetal thymus organ cultures (FTOC) in the presence of mAbs specific for the conventional IL-7 receptor (IL-7R) and for the common gamma (gamma c) chain. In FTOC, the development of CD4-CD8- double-negative thymocytes to CD4+
Processing of viral glycoproteins by the subtilisin-like endoprotease furin and its inhibition by specific peptidylchloroalkylketones.: Biochimie. 1994;76(3-4):217-25. Unique Identifier : AIDSLINE MED/95119121; Garten W; Hallenberger S; Ortmann D; Schafer W; Vey M; Angliker H; Shaw E; Klenk HD; Institut fur Virologie, Philipps-Universitat Marburg, Germany.; The spike glycoproteins of many enveloped viruses are proteolytically cleaved at the carboxytermini of sequences containing the basic motif R-X-K/R-R. Cleavage is often necessary for the fusion capacity of the glycoproteins and, thus, for virus infectivity. Among these viruses are pathogenic avian influenza viruses, h
T4-lymphocyte endoprotease responsible for the proteolytic processing of HIV-1 gp160, like Kex2p endoprotease, is a calcium-dependent enzyme.: Biochimie. 1994;76(3-4):251-6. Unique Identifier : AIDSLINE MED/95119126; Moulard M; Achstetter T; Ikehara Y; Bahraoui E; Institut fur Virologie, Klinikum der Philipps-Universitat; Marburg, Germany.; In the present study we show that precursor gp160 is cleaved in the HIV-1 infected CEM (CD4+) cell line preferentially in the presence of calcium ions demonstrating that the responsible cellular endoprotease is a calcium-dependent enzyme. Taking into account this similarity, a synthetic peptide modelling the cleavage
AIDS and the adolescent [editorial]: Int J STD AIDS. 1994 Sep-Oct;5(5):305-9. Unique Identifier : AIDSLINE MED/95119141; Graham CA; Recent findings on young people s response to HIV/AIDS and its perceived relevance to their sexual lives are reviewed. Research into adolescent sexual behaviour suggests a trend, over the last 2 decades, for an earlier age of first intercourse and a greater number of recent and lifetime sexual partners. Older cohorts
Cerebrospinal fluid proteins in neurosyphilis and HIV infection [editorial]: Int J STD AIDS. 1994 Sep-Oct;5(5):310-7. Unique Identifier : AIDSLINE MED/95119142; Keir G; This paper briefly reviews the factors which influence the concentrations of proteins, particularly immunoglobulins, within the CSF and how antibodies which are locally synthesized within the central nervous system can be detected by the laboratory. The use of nitrocellulose immunoblotting for the identification of an
GPs, STDs and life insurance.: Int J STD AIDS. 1994 Sep-Oct;5(5):318-21; discussion 322-6. Unique Identifier : AIDSLINE MED/95119143; Keane FE; Young SM; Department of Genito-urinary Medicine, Leicester Royal Infirmary,; UK.; We sought to ascertain general practitioners (GPs) views on their patients attendances at genitourinary medicine (GUM) departments regarding methods of referral, record keeping and supplying of information to insurance companies. A questionnaire was sent to 429 local GPs of whom 294 (68%) responded. A written means
Attitudes towards and experience of general practice among HIV-positive patients in the Republic of Ireland.: Int J STD AIDS. 1994 Sep-Oct;5(5):327-31. Unique Identifier : AIDSLINE MED/95119144; Bradley F; Bury G; Mulcahy F; O'Kelly F; Shannon W; Langton-Burke D; HIV Primary Care Research Project, Dublin, Ireland.; In order to study their attitudes to and experience of general practitioner care, 150 attenders at the only HIV specialist clinic in the Republic of Ireland were asked to complete an anonymous, self administered questionnaire. (81%)
Seroprevalence and incidence of sexually transmitted diseases in a rural Ugandan population.: Int J STD AIDS. 1994 Sep-Oct;5(5):332-7. Unique Identifier : AIDSLINE MED/95119145; Wagner HU; Van Dyck E; Roggen E; Nunn AJ; Kamali A; Schmid DS; Dobbins JG; Mulder DW; Medical Research Council (UK) Programme on AIDS in Uganda,; Entebbe.; The aim of the study was to determine in a rural population the age- and sex-specific prevalence and incidence rates of serological reactivity of 5 common sexually transmitted diseases (STDs) and their association with HIV-1 antibody status. Of the adult population of two villages (529 adults aged 15 years or more) 29
Abdominal pain in women attending a genitourinary medicine clinic: who has PID?: Int J STD AIDS. 1994 Sep-Oct;5(5):338-42. Unique Identifier : AIDSLINE MED/95119146; Stacey CM; Munday PE; Department of Genitourinary Medicine, St Mary's Hospital, London.; Eighty-one women who presented to a genitourinary medicine clinic with mild to moderate acute or chronic abdominal pain were studied in order to compare the clinical features of those who had pelvic inflammatory disease (PID) and those who did not. The diagnosis was made by laparoscopy, and PID was detected in 14%, ad
The role of early colposcopy in the management of females with first episode anogenital warts.: Int J STD AIDS. 1994 Sep-Oct;5(5):343-5. Unique Identifier : AIDSLINE MED/95119147; Ward KA; Houston JR; Lowry BE; Maw RD; Dinsmore WW; Department of Genitourinary Medicine, Royal Victoria Hospital,; Belfast, UK.; 212 females attending a genitourinary medicine (GUM) clinic with first episode anogenital warts were screened by cervical cytology and colposcopy/histology for the presence of cervical epithelial abnormalities in keeping with infection by the human papillomavirus (HPV infection) and/or cervical intraepithelial neoplas
Sexual behaviour among London GUM clinic attenders: implications for HIV education.: Int J STD AIDS. 1994 Sep-Oct;5(5):346-52. Unique Identifier : AIDSLINE MED/95119148; Filipe EM; Strauss SB; Beck EJ; Whitaker L; Wadsworth J; Renton AM; Goldmeier D; Miller DL; Academic Department of Public Health, St Mary's Hospital and; Medical School, London, UK.; The aim of this study was to describe the sexual behaviour of a sample of genitourinary medicine (GUM) clinic attenders, 5 years after the launch of the UK government HIV media campaigns. A gender-specific and anonymous cross-sectional self-completion questionnaire was modified from the National Survey of Sexual Attit
The use of intravenous pentamidine as prophylaxis against Pneumocystis carinii pneumonia in patients with HIV infection.: Int J STD AIDS. 1994 Sep-Oct;5(5):353-5. Unique Identifier : AIDSLINE MED/95119149; Schroeder KE; Barton SE; Department of Genitourinary Medicine, St Stephen's Clinic,; Chelsea and Westminster Hospital, London, UK.; The purpose of this study is to report on the use of monthly intravenous pentamidine as prophylaxis against Pneumocystis carinii pneumonia (PCP) within a central London HIV unit. A retrospective case note analysis of HIV-seropositive individuals using intravenous pentamidine as PCP prophylaxis was carried out. Aspects
Sampling for vaginal candidosis: how good is it?: Int J STD AIDS. 1994 Sep-Oct;5(5):356-8. Unique Identifier : AIDSLINE MED/95119150; Emmerson J; Gunputrao A; Hawkswell J; Dexter A; Sykes R; Searle S; Cross A; Nathan PM; Department of Genitourinary Medicine, Retford Hospital, UK.; In defined patient populations attending a genitourinary medicine department, screening for vaginal candidosis resulted in 26.3% positive rate. Microscopy using Gram-stained slide was useful in early diagnosis and resulted in the detection of 64.8% of symptomatic cases. Samples from the anterior fornix proved most sen
High prevalence of herpes simplex virus type 1 in female anogenital herpes simplex in Newcastle upon Tyne 1983-92 [see comments]: Int J STD AIDS. 1994 Sep-Oct;5(5):359-61. Unique Identifier : AIDSLINE MED/95119151; Tayal SC; Pattman RS; Department of Genito-Urinary Medicine, Newcastle General; Hospital, Newcastle upon Tyne, UK.; This retrospective study was undertaken to evaluate the prevalence of the viral types and temporal epidemiology in patients with ano- genital herpes between 1983-92. One thousand one hundred and thirty-five patients with anogenital herpes were available for analysis. The annual i
Comparison of the influence of spermicidal and non-spermicidal contraception on bacterial vaginosis, candidal infection and inflammation of the vagina--a preliminary study.: Int J STD AIDS. 1994 Sep-Oct;5(5):362-4. Unique Identifier : AIDSLINE MED/95119152; Jones BM; Eley A; Hicks DA; Patel R; Wordsworth JM; Department of Experimental and Clinical Microbiology, University; Medical School, Sheffield, UK.; This preliminary study compared the signs, symptoms and prevalence of bacterial vaginosis (BV) and candidal infections in women using spermicides, with those using other forms of contraception, to establish whether nonoxynol-9 had any therapeutic value against BV or gave rise to vaginal candidiasis and inflammation. O
Risk behaviours for HIV infection and sexually transmitted diseases among female sex workers from Copenhagen.: Int J STD AIDS. 1994 Sep-Oct;5(5):365-7. Unique Identifier : AIDSLINE MED/95119153; Alary M; Worm AM; Kvinesdal B; Centre de Recherche, Hopital du Saint-Sacrement, Quebec,; Canada.; In 1990-91, 237 female sex workers from Copenhagen were enrolled in a larger study performed in 9 European countries. None of 206 women accepting serological testing was HIV-infected despite the fact that 36 (17.5%) were injecting drug users (IDU). Whereas 95% of the women always used condoms with clients over the las
Female genital schistosomiasis as a risk-factor for the transmission of HIV.: Int J STD AIDS. 1994 Sep-Oct;5(5):368-72. Unique Identifier : AIDSLINE MED/95119154; Feldmeier H; Krantz I; Poggensee G; Fachbereich Grundlagenmedizin, Freie Universitat Berlin,; Germany.; Sexually transmitted diseases increase the probability for HIV transmission, presumably through lesions in the genital mucosa. Female genital schistosomiasis, a special form of urinary schistosomiasis due to infection with Schistosoma haematobium, may be another risk-factor for transmission of HIV. From published data
An audit of safer sexual practice and knowledge in patients attending a genitourinary medicine department.: Int J STD AIDS. 1994 Sep-Oct;5(5):373. Unique Identifier : AIDSLINE MED/95119155; Carlin EM; Munn N; Meehan F; Murphy SM; Department of Genito-Urinary Medicine, Central Middlesex; Hospital, London, UK.
Audit of patients' knowledge of their oral contraceptive pill.: Int J STD AIDS. 1994 Sep-Oct;5(5):373-4. Unique Identifier : AIDSLINE MED/95119156; Schroeder K; Dwyer D; Barton SE; Department of Genitourinary Medicine, Chelsea & Westminster; Hospital, London, UK.
Audit evaluating the value of routine screening of Chlamydia trachomatis urethral infections in men [see comments]: Int J STD AIDS. 1994 Sep-Oct;5(5):374-5. Unique Identifier : AIDSLINE MED/95119157; Harry TC; Saravanamuttu KM; Rashid S; Shrestha TL; Department of Genito-Urinary Medicine, Microbiology Sunderland; City Hospitals, UK.
Surveillance of sexual behaviour and patients' reasons for requesting HIV tests.: Int J STD AIDS. 1994 Sep-Oct;5(5):375. Unique Identifier : AIDSLINE MED/95119158; Wardropper AG; Sankar KN; Ong EL; Newcastle General Hospital.
Time off work and financial implications of genitourinary medicine clinic attendance.: Int J STD AIDS. 1994 Sep-Oct;5(5):376. Unique Identifier : AIDSLINE MED/95119159; Lim CC; Maw RD; Dinsmore WW; Armstrong DK; Genito-Urinary Medicine Department, Royal Victoria Hospital,; Belfast, Northern Ireland.
A survey of Thai sexual behaviour and risk of HIV infection [letter]: Int J STD AIDS. 1994 Sep-Oct;5(5):377-8. Unique Identifier : AIDSLINE MED/95119160; Sittitrai W; Phanuphak P; Barry J; Brown T
Gonorrhoea in homosexual and bisexual men [letter]: Int J STD AIDS. 1994 Sep-Oct;5(5):379-80. Unique Identifier : AIDSLINE MED/95119162; Kinghorn GR
Cervical epithelial abnormalities in females with and without genital warts [letter]: Int J STD AIDS. 1994 Sep-Oct;5(5):380-1. Unique Identifier : AIDSLINE MED/95119163; Ward KA; Lowry BE; Houston JR; Maw RD
The prevalence of urogenital Chlamydia trachomatis infection in a refugee community in El Salvador [letter]: Int J STD AIDS. 1994 Sep-Oct;5(5):381-2. Unique Identifier : AIDSLINE MED/95119164; Shamomesh M; Shamanesh M
[Total hip endoprostheses--characteristic aspects from the anesthesiologic viewpoint (see comments)]: Anasthesiol Intensivmed Notfallmed Schmerzther. 1994 Nov;29(7):385-99. Unique Identifier : AIDSLINE MED/95119273; Ullrich W; Holz U; Krier C; Klinik fur Anasthesiologie und operative Intensivmedizin,; Katharinenhospital Stuttgart.; Total hip replacement is a frequently practised operation. Depending on age, circumstances and individual assessment, cemented, non-cemented and hybrid forms are used. Apart from general risks, such as vascular and/or neural injuries, thrombosis and infections, there are specific risks, depending on the surgical techn
What is the correlation between soluble CD23 and IgE levels in human immunodeficiency virus-1 infection? [letter]: Int J Clin Lab Res. 1994;24(3):180. Unique Identifier : AIDSLINE MED/95119432; Perrella O; Carrieri PB; Perrella A; Soscia E; Guarnaccia D; Finelli L
The Skeleton in the Hospital Closet--20 Years Late: Malnutrition in Patients with GI Disease, Cancer and AIDS. Los Angeles, California, October 1-2, 1994. Abstracts.: Nutrition. 1994 Sep-Oct;10(5):445-506. Unique Identifier : AIDSLINE MED/95119498
[The significance of AIDS for mortality in Berlin (West)]: Gesundheitswesen. 1994 Nov;56(11):611-6. Unique Identifier : AIDSLINE MED/95119506; Baier WK; Haberland J; Schott J; Bergmann KE; Robert Koch-Institut Berlin.; Following a long-term decline, death rates due to infectious diseases in West-Berlin men have dramatically increased since 1983. The Berlin mortality statistics introduced AIDS as a specific cause of death only in 1989. However, opportunistic infections, a negligible quantity until 1983, and pointing to AIDS as the un
[Female prostitution and HIV/AIDS--review of the literature on epidemiology and personal observations in a contact center for drug dependent patients]: Gesundheitswesen. 1994 Nov;56(11):617-21. Unique Identifier : AIDSLINE MED/95119507; Marquart KH; Gesundheitsamt der Landeshauptstadt Stuttgart.; Epidemiological studies show that intravenous drug use represents the main risk for HIV/AIDS infection among female prostitutes in Germany . According to current information, HIV/AIDS infections are not more prevalent among prostitutes who are not intravenous drug users than in the
[Infectious disease observed upon travel return. Retrospective and prospective investigation conducted in 1992 with 15 hospitals]: Bull Soc Pathol Exot. 1993;86(5 Pt 2):414-7. Unique Identifier : AIDSLINE MED/95119630; Cuzin-Ferrand L; Bequet L; Armengaud M; Service des Maladies Infectieuses et Tropicales, Hopital Purpan,; Toulouse, France.; We report 1,302 cases of patients observed in the Department of Infectious Diseases in 15 French hospitals: 1,036 in a retrospective study in 1991; 266 in a prospective study in 1992. 48% of patients suffered from malaria, diarrhoea or hepatitis; 50% were admitted in the hospital. We have numbered 191 cases of non tro
[Paraplegia associated with HTLV 1 in Martinique. Study of 271 cases including 70 with neuromuscular involvement]: Bull Soc Pathol Exot. 1993;86(5 Pt 2):433-8. Unique Identifier : AIDSLINE MED/95119634; Smadja D; Cabre P; Bellance R; Vernant JC; Service de neurologie, Hopital Pierre Zobda-Quitman,; Fort-de-France.; To date, 271 cases of HTLV1-associated paraplegia have been observed in Martinique (French West Indies). The clinical picture consisted mostly in a spastic paraparesis or paraplegia with sphincter disturbances (80%) and lower limbs
[Primitive Sjogren's syndrome in France and Ecuador. Possible involvement od HTLV 1]: Bull Soc Pathol Exot. 1993;86(5 Pt 2):439-41. Unique Identifier : AIDSLINE MED/95119635; Cevallos R; Geffray L; Guillevin L; Cevallos L; Veyssier P; Darnige L; Procel C; Service de medecine interne, CH de Compiegne.; The authors study the possible involvement of retrovirus in Sjogren s syndrome. They report a preliminary study of 20 French and 13 Ecuadorian patients with a primary Sjogren syndrome. A previous epidemiologic study showed a HTLV1 seroprevalence going from 0.04 to 6% on different regions of Ecuador. The results of thi
[Epidemiological characteristics of HIV infection in Martinique]: Bull Soc Pathol Exot. 1993;86(5 Pt 2):465-6. Unique Identifier : AIDSLINE MED/95119640; Cales-Quist D; Neisson-Vernant C; Chout R; Monplaisir N; Cesaire R; Andrillon B; Sobesky G; Dispensaire MST, Fort-de-France.; The epidemiologic study of HIV infected patients in Martinique from 1985 to 1992 allowed to point out a stability of new cases by year, and confirm the heterosexual transmission in this area. The sexual comportment of Martinicans se
[Prurigo in tropical area. Importance of its association with HIV infection]: Bull Soc Pathol Exot. 1993;86(5 Pt 2):512-6. Unique Identifier : AIDSLINE MED/95119650; Pradinaud R; Sainte-Marie D; Strobel M; Degarve B; Roul S; Service de Dermatologie-Venerologie, Centre Hospitalier; General, Cayenne.; The term prurigo applies to a classic chronic skin disease of children (P. strophulus) which is becoming found very seldom in developed countries, but remains extraordinarily prevalent in tropical areas. This striking geographical distribution relies on its ectoparasitic origin. Some peculiar aspects of prurigo, obser
German parliament investigates HIV infections [news]: BMJ. 1994 Nov 26;309(6966):1389-90. Unique Identifier : AIDSLINE MED/95119680; Karcher H
What's happening to AIDS? [editorial]: BMJ. 1994 Dec 10;309(6968):1523-4. Unique Identifier : AIDSLINE MED/95119725; Johnson AM; De Cock KM
Does symptomatic primary HIV-1 infection accelerate progression to CDC stage IV disease, CD4 count below 200 x 10(6)/l, AIDS, and death from AIDS?: BMJ. 1994 Dec 10;309(6968):1535-7. Unique Identifier : AIDSLINE MED/95119739; Lindback S; Brostrom C; Karlsson A; Gaines H; Department of Infectious Diseases, Huddinge Hospital, Karolinska; Institute, Stockholm, Sweden.; OBJECTIVE--To investigate the prognostic significance of symptomatic primary HIV-1 infection. DESIGN--Prospective study of homosexual men seroconverting to HIV in 1985 and 1986. Patients were followed up at least three times yearly with clinical examinations and T cell subset determinations for an average of 7.2 years
HIV disease progression in 854 women and men infected through injecting drug use and heterosexual sex and followed for up to nine years from seroconversion. Italian Seroconversion Study [see comments]: BMJ. 1994 Dec 10;309(6968):1537-42. Unique Identifier : AIDSLINE MED/95119740; Cozzi Lepri A; Pezzotti P; Dorrucci M; Phillips AN; Rezza G; Istituto Superiore di Sanita, Laboratorio di Epidemiologia e; Biostatistica, Centro Operativo AIDS, Rome, Italy.; OBJECTIVE--To compare the progression of HIV-1 infection in men and women followed up for up to nine years after an accurately estimated date of seroconversion. DESIGN--Prospective observational study. SETTING--16 HIV outpatient clinics across Italy . SUBJECTS--321 women and 533 men
Impact of HIV infection on Zambian businesses.: BMJ. 1994 Dec 10;309(6968):1549-50. Unique Identifier : AIDSLINE MED/95119743; Baggaley R; Godfrey-Faussett P; Msiska R; Chilangwa D; Chitu E; Porter J; Kelly M; Kara Counselling and Training Trust, Lusaka, Zambia.
Epitrochlear lymph nodes as marker of HIV disease in sub-Saharan Africa.: BMJ. 1994 Dec 10;309(6968):1550-1. Unique Identifier : AIDSLINE MED/95119744; Malin A; Ternouth I; Sarbah S; Department of Clinical Pharmacology, University of Zimbabwe,; Harare.
Sydney surgeon accused of HIV transfer [news]: BMJ. 1994 Dec 17;309(6969):1603. Unique Identifier : AIDSLINE MED/95119783; Zinn C
Heart muscle disease related to HIV infection: prognostic implications [see comments]: BMJ. 1994 Dec 17;309(6969):1605-7. Unique Identifier : AIDSLINE MED/95119785; Currie PF; Jacob AJ; Foreman AR; Elton RA; Brettle RP; Boon NA; Department of Cardiology, Royal Infirmary, Edinburgh.; OBJECTIVES--To determine the natural course of heart muscle disease in patients infected with HIV. DESIGN--Prospective echocardiographic survey and observational study over four years. SETTING--Edinburgh. SUBJECTS--296 adults infected with HIV (mean age 32.7 years (range 21.5 to 67.6) drawn from all the major groups a
Nasal absorption of zidovudine and its transport to cerebrospinal fluid in rats.: Biol Pharm Bull. 1994 Aug;17(8):1135-7. Unique Identifier : AIDSLINE MED/95119989; Seki T; Sato N; Hasegawa T; Kawaguchi T; Juni K; Faculty of Pharmaceutical Sciences, Josai University, Saitama,; Japan.; The nasal absorption of zidovudine ( AZT ) and its subsequent transport to cerebrospinal fluid (CSF) was examined in rats. Both rapid absorption and a high CSF concentration were observed after the nasal application. Plasma and CSF concentrations of AZT
Teleocidins and benzolactams inhibit cell killing by human immunodeficiency virus type 1 (HIV-1).: Biol Pharm Bull. 1994 Aug;17(8):1147-9. Unique Identifier : AIDSLINE MED/95119993; Endo Y; Ohno M; Hirano M; Fujiwara T; Sato A; Hinuma Y; Shudo K; Faculty of Pharmaceutical Sciences, University of Tokyo, Japan.; Teleocidin B-4 and structurally related synthetic benzolactams were found to be potent inhibitors of cell killing by HIV-1. One of the benzolactams, (-)-BL-V8-310, showed a high selectivity index.
[Clinical and epidemiological aspects of AIDS in the Hospital of the Federal University of Mato Grosso (letter)]: Rev Assoc Med Bras. 1994 Apr-Jun;40(2):137-9. Unique Identifier : AIDSLINE MED/95120017; Souto FJ; Hueb M; Conceicao YT; Maitelli A
Thyroid function in children with perinatally acquired antibodies to human immunodeficiency virus.: J Pediatr Endocrinol. 1994 Jul-Sep;7(3):201-4. Unique Identifier : AIDSLINE MED/95120090; Blethen SL; Nachman S; Chasalow FI; Department of Pediatrics, State University of New York at Stony; Brook, NY 11794-8111.; We measured T4, T3, TSH, and TBG in 53 children (both asymptomatic and symptomatic) with human immunodeficiency virus (HIV) antibodies, and 17 controls. Although most had normal T3 and T4 levels, two children with acquired immuno-deficiency syndrome (AIDS), who were very ill when studied, had low T3 values. TBG and TS
Isolation, identification and determination of sulfamethoxazole and its known metabolites in human plasma and urine by high-performance liquid chromatography.: J Chromatogr B Biomed Appl. 1994 Aug 19;658(2):327-40. Unique Identifier : AIDSLINE MED/95120147; Vree TB; van der Ven AJ; Verwey-van Wissen CP; van Ewijk-Beneken Kolmer EW; Swolfs AE; van Galen PM; Amatdjais-Groenen H; Department of Clinical Pharmacy, Academic Hospital Nijmegen Sint; Radboud, Netherlands.; From human urine the following metabolites of sulfamethoxazole (S) were isolated by preparative HPLC: 5-methylhydroxysulfamethoxazole (SOH), N4-acetyl-5-methylhydroxysulfamethoxazole (N4SOH) and sulfamethoxazole-N1-glucuronide (Sgluc). The compounds were identified by NMR, mass spectrometry, infrared spectrometry, hyd
Effects of frailty in survival analysis.: Stat Methods Med Res. 1994;3(3):227-43. Unique Identifier : AIDSLINE MED/95120180; Aalen OO; University of Oslo, Norway.; Unobserved individual heterogeneity, also called frailty, is a major concern in the application of survival analysis. Hazard rates do not give direct information on the change over time in the individual risk, but are strongly influenced by selection effects operating in the population. The individuals surviving up to
The influence of gastric pH on the pharmacokinetics of fluconazole: the effect of omeprazole.: Int J Clin Pharmacol Ther. 1994 Sep;32(9):491-6. Unique Identifier : AIDSLINE MED/95120233; Zimmermann T; Yeates RA; Riedel KD; Lach P; Laufen H; Department of Pharmacology, Pfizer/Mack Research and Development,; Illertissen.; AIDS patients may have achlorhydria, a condition that could result in drug malabsorption, especially of antifungals. The effect of a reduction in the production of gastric acid on the pharmacokinetics of the antimycotic fluconazole after a single 100 mg dose was investigated in a randomized two-way crossover study wit
Liposomes as carriers for vaccines.: Immunomethods. 1994 Jun;4(3):217-22. Unique Identifier : AIDSLINE MED/95120365; Wassef NM; Alving CR; Richards RL; Department of Membrane Biochemistry, Walter Reed Army Institute; of Research, Washington, District of Columbia 20307-5100.; A liposome vaccine formulation that has been successfully used in both animal immunization studies and clinical trials is described. Issues concerning the choice of components for the liposomal vaccine formulation are discussed, especially with respect to the lipid components and the adjuvant. A procedure is described
Experience with brain biopsy in acquired immune deficiency syndrome-related focal lesions of the central nervous system.: Br J Surg. 1994 Oct;81(10):1508-11. Unique Identifier : AIDSLINE MED/95120402; Iacoangeli M; Roselli R; Antinori A; Ammassari A; Murri R; Pompucci A; Scerrati M; Institute of Neurosurgery, Catholic University School of; Medicine, Rome, Italy.; Involvement of the central nervous system (CNS) in patients with acquired immune deficiency syndrome (AIDS) is an increasing clinical problem. The most common brain complications are toxoplasmosis (50-70 per cent), primary CNS lymphoma (20-30 per cent) and progressive multifocal le
Intraventricular administration of a FIV-envelope protein induces sleep architecture changes in rats.: Brain Res. 1994 Oct 3;659(1-2):254-8. Unique Identifier : AIDSLINE MED/95120602; Prospero-Garcia O; Herold N; Waters AK; Phillips TR; Elder JH; Henriksen SJ; Department of Neuropharmacology CVN-13, Scripps Research; Institute, La Jolla, CA 92037.; Fifteen adult male Sprague-Dawley rats were implanted with a set of electrodes for standard sleep recordings. A stainless steel cannula was also implanted into the lateral ventricle of these rats. Fifteen additional rats were implanted with a cannula alone. Rats with electrodes were habituated for 3 days or more to th
Bacterial esophagitis associated with CD4+ T-lymphocytopenia without HIV infection. Possible role of corticosteroid treatment.: Dig Dis Sci. 1995 Jan;40(1):183-5. Unique Identifier : AIDSLINE MED/95121089; Richert SM; Orchard JL; Department of Medicine and Gastroenterology, Mercy Hospital,; Pittsburgh, Pennsylvania 15219-5166.; Although infectious esophagitis is usually due to infection with Candida, herpes virus, or cytomegalovirus , bacterial esophagitis is occasionally observed. Recently, patients have been reported with CD4+ T-lymphocytopenia without HIV infection. Bacterial esophagitis per se has not
Cryptosporidium gastropathy. Presentation of a case and review of the literature.: Dig Dis Sci. 1995 Jan;40(1):186-90. Unique Identifier : AIDSLINE MED/95121090; Massimillo AJ; Chang J; Freedman L; Baxi R; Kanth N; Pellecchia C; Gastroenterology Division, Nassau County Medical Center, East; Meadow, New York 11554.
[Disseminated extrapulmonary tuberculosis in idiopathic CD4-lymphocytopenia]: Dtsch Med Wochenschr. 1995 Jan 5;120(1-2):23-8. Unique Identifier : AIDSLINE MED/95121188; Neukirch B; Kremer GJ; Innere Abteilung des St.-Josef-Hospitals, Oberhausen-Mitte.; A previously healthy, now 42-year-old man suddenly fell ill with bouts of septic fever up to 39.5 degrees C, sweats and weight loss without any demonstrable organ involvement. Physical examination on hospitalization 3 weeks after onset of the illness was unremarkable. Blood sedimentation rate at one hour was 123 mm. T
[New infectious diseases caused by viruses. Current knowledge and preliminary information]: Dtsch Med Wochenschr. 1995 Jan 5;120(1-2):37-44. Unique Identifier : AIDSLINE MED/95121192; Doerr HW; Institut fur Medizinische Virologie, Abteilung des Klinikums im; Zentrum der Hygiene der Universitat Frankfurt/Main.
HIV seropositivity in children admitted with diarrhoea at Eldoret District Hospital, Kenya.: East Afr Med J. 1994 Oct;71(10):631-4. Unique Identifier : AIDSLINE MED/95121231; Esamai F; Buku GM; Department of Child Health, Paediatrics and Adolescent Medicine,; Faculty of Health Sciences, Moi University, Eldoret, Kenya.; Fifty seven children aged 2 years and below admitted to Paediatric ward of Eldoret District Hospital with a diagnosis of diarrhoea were studied for HIV infection. A total of 29 (50.9%) cases were found to be positive with no gender difference. 17 (70.8%) of 24 cases with diarrhoea of over 14 days duration were positiv
Metabolic abnormalities and new-onset seizures in human immunodeficiency virus-seropositive patients.: Epilepsia. 1995 Feb;36(2):146-50. Unique Identifier : AIDSLINE MED/95121280; Van Paesschen W; Bodian C; Maker H; Department of Neurology, Mount Sinai Medical Center, New York,; New York.; Seizures are a recognized complication of human immunodeficiency virus (HIV)-type-1 infection. CNS disease processes in these patients include encephalitis, focal brain lesions, and meningitis. Metabolic causes of seizures have received little attention. In a retrospective study, we selected 68 HIV-seropositive patien
Detection of tryptase TL2 and CD26 antigen in brain-derived cells non-permissive to T-cell line-tropic human immunodeficiency virus type 1.: FEBS Lett. 1995 Jan 16;358(1):48-52. Unique Identifier : AIDSLINE MED/95121458; Shimizu N; Kobayashi M; Liu HY; Kido H; Hoshino H; Department of Hygiene and Virology, Gunma University School of; Medicine, Japan.; Tryptase TL2 purified from MOLT-4 human T cells binds to the envelope protein of human immunodeficiency virus type 1 (HIV-1). Tryptase TL2 and CD26 antigen are supposed to play roles in HIV-1 entry into cells. Although CD4 is a principal receptor for HIV-1, brain cells expressing the CD4 antigen are not permissive to
The effect of fetal infection with human immunodeficiency virus type 1 on birthweight and length of gestation. SIGO Study Group of HIV Infection in Pregnancy.: Eur J Obstet Gynecol Reprod Biol. 1994 Oct;57(1):13-7. Unique Identifier : AIDSLINE MED/95121526; Spinillo A; Iasci A; Dal Maso J; Di Lenardo L; Grella P; Guaschino S; Department of Obstetrics and Gynecology, University of Pavia,; IRCCS Policlinico S. Matteo, Italy.; We sought to evaluate the effect of vertical transmission of human immunodeficiency virus type 1 (HIV-1) on birthweight and length of gestation. For this purpose we used maternal and pregnancy data of 559 HIV-1-seropositive pregnant women delivered at 13 Italian centers from 1985 to 1991. The mother-to-child transmiss
The aspartic proteinase of equine infectious anaemia virus.: Biochem Soc Trans. 1994 Aug;22(3):304S. Unique Identifier : AIDSLINE MED/95121597; Powell DJ; Le Grice SJ; Kay J; Department of Biochemistry, University of Wales, Cardiff.
Antigenic peptides.: FASEB J. 1995 Jan;9(1):37-42. Unique Identifier : AIDSLINE MED/95121804; Dyson HJ; Wright PE; Department of Molecular Biology, Scripps Research Institute, La; Jolla, California 92037.; Although most short, linear peptide fragments of proteins are unstructured in aqueous solution, a number of immunogenic and antigenic peptides have been shown to have conformational preferences for structured forms. By using mainly NMR and CD spectroscopy, it has been possible to detect and quantify quite small popula
Characterization of hUCRBP (YY1, NF-E1, delta): a transcription factor that binds the regulatory regions of many viral and cellular genes.: Gene. 1994 Dec 15;150(2):259-66. Unique Identifier : AIDSLINE MED/95121912; Becker KG; Jedlicka P; Templeton NS; Liotta L; Ozato K; Laboratory of Molecular Growth Regulation, National Institute of; Child Health and Human Development, National Institutes of; Health, Bethesda, MD 20892.; The UCRBP (YY1, delta, NF-E1) protein has been isolated for its ability to bind to the UCR (upstream conserved region) site present in the conserved murine leukemia virus long terminal repeat. UCRBP carries a highly charged N-terminal domain and four C2-H2-type zinc fingers at its C-terminal end. The present study rev
Biological activity and intracellular location of the Tat protein of equine infectious anemia virus.: Gene. 1994 Dec 15;150(2):307-11. Unique Identifier : AIDSLINE MED/95121920; Rosin-Arbesfeld R; Mashiah P; Willbold D; Rosch P; Tronick SR; Yaniv A; Gazit A; Department of Human Microbiology, Sackler School of Medicine, Tel; Aviv University, Israel.; The Tat protein of equine infectious anemia virus (EIAV) was synthesized in Escherichia coli using the inducible expression plasmid, pET16b, which contains a His.Tag leader, thus allowing for rapid and efficient enrichment of the histidine-tagged protein by metal affinity chromatography. Yields of up to 20 mg of Tat w
Monoclonal antibody HML-1 reactivity with adult T-cell leukaemia/lymphoma and other lymphomas.: Histopathology. 1994 Sep;25(3):229-36. Unique Identifier : AIDSLINE MED/95122030; Kitajima S; Tokunaga M; Goto M; Sato E; Utsunomiya A; Ohtsuka M; Hanada S; Arima T; Department of Pathology, Kagoshima University Faculty of; Medicine, Japan.; Human T-cell leukaemia/lymphoma virus type 1 (HTLV-1), a causative virus of adult T-cell leukaemia/lymphoma (ATLL), is known to be transmitted by breast-feeding. Using a monoclonal antibody HML-1 which labels human intestinal intra-epithelial T lymphocytes, we have immunohistochemically examined ATLL tissues in order
Role of lymphoid organs in the pathogenesis of human immunodeficiency virus (HIV) infection.: Immunol Rev. 1994 Aug;140:105-30. Unique Identifier : AIDSLINE MED/95122080; Pantaleo G; Graziosi C; Demarest JF; Cohen OJ; Vaccarezza M; Gantt K; Muro-Cacho C; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.; The pathogenic mechanisms of HIV disease are multifactorial and multi-phasic. The common denominator of the disease is the profound immunosuppression that occurs in the vast majority of infected patients. Studies in lymphoid tissues in HIV disease have provided considerable insight into the pathogenic processes involv
Antigenic variation of primate lentiviruses in humans and experimentally infected macaques.: Immunol Rev. 1994 Aug;140:131-46. Unique Identifier : AIDSLINE MED/95122081; Fenyo EM; Department of Microbiology and Tumorbiology, MTC, Karolinska; Institute, Stockholm, Sweden.; Neutralizing antibodies in primate lentivirus infections closely parallel the pathogenic process. Fast progression to disease is concomitant with lack of neutralizing antibodies to autologous virus. Slow or no progression to disease is linked with production of neutralizing antibodies to autologous virus. Moreover, th
The role of CD4 and its downmodulation in establishment and maintenance of HIV-1 infection.: Immunol Rev. 1994 Aug;140:147-71. Unique Identifier : AIDSLINE MED/95122082; Bour S; Geleziunas R; Wainberg MA; Lady Davis Institute-Jewish General Hospital, Montreal, Quebec,; Canada.
Changing virus-host interactions in the course of HIV-1 infection.: Immunol Rev. 1994 Aug;140:35-72. Unique Identifier : AIDSLINE MED/95122083; Miedema F; Meyaard L; Koot M; Klein MR; Roos MT; Groenink M; Fouchier RA; Van't Wout AB; Tersmette M; Schellekens PT; et al; Department of Clinical Viro-immunology, Central Laboratory of The; Netherlands Red Cross Blood Transfusion Service, Amsterdam.
Cytokines from lymphoid organs of HIV-infected patients: production and role in the immune disequilibrium of the disease and in the development of B lymphomas.: Immunol Rev. 1994 Aug;140:5-34. Unique Identifier : AIDSLINE MED/95122084; Emilie D; Fior R; Llorente L; Marfaing-Koka A; Peuchmaur M; Devergne O; Jarrousse B; Wijdenes J; Boue F; Galanaud P; INSERM U131, Clamart, France.
Role of TH1/TH2 cytokines in HIV infection.: Immunol Rev. 1994 Aug;140:73-92. Unique Identifier : AIDSLINE MED/95122085; Romagnani S; Del Prete G; Manetti R; Ravina A; Annunziato F; De Carli M; Mazzetti M; Piccinni MP; D'Elios MM; Parronchi P; et al; Department of Allergy & Clinical Immunology, University of; Florence, Italy.; Different experimental approaches were used to prove or disprove the TH1/TH2 switch theory of HIV-infection. No increase, or even a decrease, in the production of TH2-type cytokines (IL-4, IL-5, and IL-10) by either bulk circulating mononuclear cells or CD4+ T-cell clones generated by PHA stimulation of single T cells
Structural rearrangements in the transmembrane glycoprotein after receptor binding.: Immunol Rev. 1994 Aug;140:93-104. Unique Identifier : AIDSLINE MED/95122086; Matthews TJ; Wild C; Chen CH; Bolognesi DP; Greenberg ML; Department of Surgery, Duke University Medical Center, Durham,; North Carolina 27710.
Relationship of HIV-1 provirus load, CD8+ CD11+ T cells and HIV-1 envelope-specific cytotoxic T lymphocytes in HIV-infected asymptomatic offients.: Immunology. 1994 Sep;83(1):81-5. Unique Identifier : AIDSLINE MED/95122129; Kundu SK; Merigan TC; Center for AIDS Research, Stanford University, CA 94305.; The course of human immunodeficiency virus (HIV) infection progresses from an acute infection, through a prolonged asymptomatic phase, to an immunocompromised state. Some of the possible mechanisms underlying immune dysfunction include decreased HIV-specific cytotoxic T lymphocyte (CTL) activity, increased suppressor
Role of CD8 T cells in primary Chlamydia infection.: Infect Immun. 1995 Feb;63(2):516-21. Unique Identifier : AIDSLINE MED/95122182; Magee DM; Williams DM; Smith JG; Bleicker CA; Grubbs BG; Schachter J; Rank RG; Department of Research Immunology, Texas Center for Infectious; Disease, San Antonio 78223.; The role of CD4 and CD8 T cells in primary Chlamydia trachomatis pneumonia was investigated by using in vivo depletion techniques to eliminate T-cell populations. Reduction of either CD4 T cells or CD8 T cells caused a significant increase in organism burden in the lungs, as measured by both quantitative culture and d
Mice immunized by primary vaginal Candida albicans infection develop acquired vaginal mucosal immunity.: Infect Immun. 1995 Feb;63(2):547-53. Unique Identifier : AIDSLINE MED/95122187; Fidel PL Jr; Lynch ME; Conaway DH; Tait L; Sobel JD; Division of Infectious Diseases, Wayne State University School of; Medicine, Detroit, Michigan.; It has been postulated that systemic cell-mediated immunity (CMI) is an important host defense mechanism against Candida infections of the vagina. However, in an estrogen-dependent murine model of experimental vaginal candidiasis, we recently showed that systemic Candida-specific Th1-type CMI induced by immunization w
Survey of infection control procedures in New Zealand dental practices.: Int Dent J. 1994 Aug;44(4):342-8. Unique Identifier : AIDSLINE MED/95122228; Treasure P; Treasure ET; Department of Restorative Dentistry, School of Dentistry,; University of Otago, Dunedin, New Zealand.; A national survey was conducted to investigate current procedures in New Zealand dental practices for control of cross-infection, and to gauge dentists perceptions of their current procedures. A questionnaire was sent to all dental practices in New Zealand, and non-returns wer
Ca2+, N-methyl-D-aspartate receptors, and AIDS-related neuronal injury.: Int Rev Neurobiol. 1994;36:1-27. Unique Identifier : AIDSLINE MED/95122286; Lipton SA; Department of Neurology, Children's Hospital, Boston,; Massachusetts.
Polyclonal use of T-cell receptor alpha for human T-cell lymphotropic virus type 1-infected T cells.: Invest Ophthalmol Vis Sci. 1995 Jan;36(1):254-8. Unique Identifier : AIDSLINE MED/95122326; Masuoka K; Sagawa K; Mochizuki M; Oizumi K; Itoh K; Department of Immunology, Kurume University School of Medicine,; Japan.; PURPOSE. To understand better the immunopathology of HTLV-I uveitis by investigating the clonality of HTLV-I-infected T-cell clones. METHODS. Eleven T-cell clones were established from the aqueous humor (six clones) and the peripheral blood (five clones) of a patient with HTLV-I uveitis, and the clonality of the HTLV-
Mycobacterium avium intracellulare infection [letter; comment]: J Bone Joint Surg Br. 1995 Jan;77(1):165. Unique Identifier : AIDSLINE MED/95122603; Spinner RJ; Sexton DJ; Vail TP
Robert Koch and the modern investigator.: Hosp Pract (Off Ed). 1995 Jan 15;30(1):99-101. Unique Identifier : AIDSLINE MED/95122679; Weller TH; Harvard School of Public Health, Boston.
A one-tube quantitative HIV-1 RNA NASBA nucleic acid amplification assay using electrochemiluminescent (ECL) labelled probes.: J Virol Methods. 1994 Sep;49(2):157-67. Unique Identifier : AIDSLINE MED/95122703; van Gemen B; van Beuningen R; Nabbe A; van Strijp D; Jurriaans S; Lens P; Kievits T; Organon Teknika B.V., Boxtel, The Netherlands.; Quantification of HIV-1 viral RNA based on co-amplification of an internal standard Q-RNA dilution series requires a number of NASBA nucleic acid amplification reactions. For each internal standard Q-RNA concentration a separate NASBA amplification has to be performed. The development of an electrochemiluminescent (EC
Quantitation of human cytomegalovirus DNA in leukocytes by end-point titration and duplex polymerase chain reaction.: J Virol Methods. 1994 Sep;49(2):195-208. Unique Identifier : AIDSLINE MED/95122707; Kulski JK; Department of Microbiology, Royal Perth Hospital, Western; Australia.; The presence of human cytomegalovirus ( CMV ) DNA and cellular DNA in leukocytes was detected by duplex polymerase chain reaction (PCR) and quantitated by end-point titration. Two different duplex PCR methods were used to co-am
Thrombomodulin in the sera of patients with multiple sclerosis and human lymphotropic virus type-1-associated myelopathy.: J Neuroimmunol. 1995 Jan;56(1):113-6. Unique Identifier : AIDSLINE MED/95122726; Tsukada N; Matsuda M; Miyagi K; Yanagisawa N; Department of Health Medical Center and Neurology, Shinshu; University, Matsumoto, Japan.; Damage to the blood-brain barrier, which mainly consists of cerebral endothelial cells, has been demonstrated in multiple sclerosis (MS) clinically and histochemically. To investigate the endothelial cell damage, we evaluated the presence of soluble thrombomodulin in the sera of patients with MS and human T lymphotrop
Hepatitis and HIV risk review [letter]: J Am Acad Dermatol. 1995 Jan;32(1):146. Unique Identifier : AIDSLINE MED/95122766; Catalano PM; Cullen SI
CNS Nocardia in AIDS patients: CT and MRI with pathologic correlation.: J Comput Assist Tomogr. 1995 Jan-Feb;19(1):15-22. Unique Identifier : AIDSLINE MED/95122791; LeBlang SD; Whiteman ML; Post MJ; Uttamchandani RB; Bell MD; Smirniotopolous JG; Department of Radiology, Jackson Memorial Hospital, Miami,; Florida.; OBJECTIVE: Since CNS nocardiosis is an often fatal yet potentially treatable infection in HIV patients, we sought to identify and characterize imaging features that may suggest the diagnosis in the appropriate clinical setting. MATERIALS AND METHODS: The CT scan (six), MR scans (one), or both (two) were evaluated in n
AIDS/HIV information hotline available [news]: J Am Dent Assoc. 1995 Jan;126(1):24. Unique Identifier : AIDSLINE MED/95122907
Direct immunofluorescence vs. culture for detecting HSV in oral ulcers: a comparison.: J Am Dent Assoc. 1995 Jan;126(1):74-8. Unique Identifier : AIDSLINE MED/95122913; MacPhail LA; Hilton JF; Heinic GS; Greenspan D; Department of Stomatology, School of Dentistry, University of; California, San Francisco 94143.; Diagnostic tests may be necessary to determine the cause of oral ulcers. Direct immunofluorescence staining of oral smears supplies results much more quickly than viral culture, the gold standard for diagnosing HSV lesions. This study compares the sensitivity and specificity of direct immunofluorescence staining vs. v
[Bouchut tubercles and AIDS. Apropos of 3 cases]: J Fr Ophtalmol. 1994;17(10):548-54. Unique Identifier : AIDSLINE MED/95122958; Campinchi-Tardy F; Darwiche A; Bergmann JF; Chedin P; Nemeth J; Campinchi R; Gaudric A; Service d'Ophtalmologie, Hopital Lariboisiere, Paris.; Tuberculosis choroidal granulomas (tubercules de Bouchut) are rare, even in patients with AIDS and active tuberculosis. The authors report the clinical and angiographical findings of three cases. Choroidal involvement was bilateral, with multiple lesions, mostly located at the posterior pole. The size of the granuloma
Morphologic and functional alterations of mucosal T cells by cholera toxin and its B subunit.: J Immunol. 1995 Feb 1;154(3):1032-40. Unique Identifier : AIDSLINE MED/95123053; Elson CO; Holland SP; Dertzbaugh MT; Cuff CF; Anderson AO; Department of Medicine, University of Alabama at Birmingham; 35294.; Despite the mucosal immunogenicity and adjuvanticity in vivo of cholera toxin (CT), both CT and CT B subunit are strong inhibitors of T cell activation in vitro. This study asked whether such T cell inhibition is relevant to the mucosal effects of CT in vivo. The activation of T cells pulsed in vitro for only 15 to 12
Role of TCR specificity in CD4 versus CD8 lineage commitment.: J Immunol. 1995 Feb 1;154(3):1057-68. Unique Identifier : AIDSLINE MED/95123056; Kersh GJ; Hedrick SM; Department of Biology, University of California, San Diego, La; Jolla 92093.; We have examined the role that TCR-alpha beta specificity plays in lineage commitment of thymocytes. Thymocytes in the process of selection have been distinguished by the expression of high levels of CD69 and CD5. The phenotype of most of these selected thymocytes is either CD4highCD8low or CD4lowCD8high, but some are
Requirement of CTLA-4 counter receptors for IL-4 but not IL-10 elevations during a primary systemic in vivo immune response.: J Immunol. 1995 Feb 1;154(3):1078-87. Unique Identifier : AIDSLINE MED/95123058; Lu P; Zhou XD; Chen SJ; Moorman M; Schoneveld A; Morris S; Finkelman FD; Linsley P; Claassen E; Gause WC; Department of Microbiology, Uniformed Services University of the; Health Sciences, Bethesda, MD 20814.; The CD28/CTLA-4 costimulatory signal is required for TCR-mediated T cell activation resulting in increased IL-2 production in vitro, but its role in IL-4 production is unclear and few studies have examined the function of CTLA-4/CD28 in the in vivo immune response. We
CD43 diminishes susceptibility to T lymphocyte-mediated cytolysis.: J Immunol. 1995 Feb 1;154(3):1097-104. Unique Identifier : AIDSLINE MED/95123060; McFarland TA; Ardman B; Manjunath N; Fabry JA; Lieberman J; Department of Medicine, New England Medical Center Hospitals,; Boston, MA 02111.; CD43 is a major membrane sialoglycoprotein expressed by cells of hematopoietic origin. One property of CD43 is its ability to interfere with heterotypic and homotypic cellular adhesion. To determine whether CD43 expression can affect cell functions requiring intercellular adhesion, we compared a CD43-positive human T
Induction of murine gamma delta T cells cytotoxic for xenogeneic rat cells.: J Immunol. 1995 Feb 1;154(3):1114-23. Unique Identifier : AIDSLINE MED/95123062; Okumura C; Suto R; Furukawa K; Ahmed SS; Furukawa K; Nakayama E; Fujii T; Shiku H; Department of Plastic and Reconstructive Surgery, Nagasaki; University School of Medicine, Japan.; C57BL/6 mice deprived or nondeprived of CD4+ and CD8+ T cells by mAbs were challenged with a rat T cell line, W7TM-1. Spleen cells obtained from CD4- and CD8-depleted animals rejecting W7TM-1 were examined by cytofluorometry, which demonstrated the presence of highly increased gamma delta type CD4-CD8- T cell populati
CDR3-independent gamma delta V delta 1+ T cell expansion in the peripheral blood of HIV-infected persons.: J Immunol. 1995 Feb 1;154(3):1418-31. Unique Identifier : AIDSLINE MED/95123095; Boullier S; Cochet M; Poccia F; Gougeon ML; AIDS and Retroviruses Department, Pasteur Institute, Paris,; France.; A majority of circulating gamma delta T cells in humans express the V delta 2 variable segment associated with the V gamma 9 segment. A minor subset uses the V delta 1 gene mainly paired with a V gamma-chain from group I. Although little is known about the function and the Ags recognized by V delta 1 T cells, their ex
Distinct signal transduction in mouse CD4+ and CD8+ splenic T cells after CD28 receptor ligation.: J Immunol. 1995 Feb 1;154(3):985-97. Unique Identifier : AIDSLINE MED/95123105; Abe R; Vandenberghe P; Craighead N; Smoot DS; Lee KP; June CH; Immune Cell Biology Program, Naval Medical Research Institute,; Bethesda, MD 20889.; Current evidence suggests that recognition of Ag/MHC by the TCR alone is insufficient to lead to T cell proliferation or effector function. For a Th cell to produce sufficient IL-2 to allow autocrine-driven clonal expansion, there is a requirement for so-called costimu
Evaluation of alternative CD4 technologies for the enumeration of CD4 lymphocytes.: J Immunol Methods. 1994 Dec 28;177(1-2):43-54. Unique Identifier : AIDSLINE MED/95123131; Nicholson JK; Velleca WM; Jubert S; Green TA; Bryan L; Division of HIV/AIDS, National Center for Infectious Diseases; 1-1202, Atlanta, GA 30333.; Enumeration of CD4+ T cells from persons infected with the human immunodeficiency virus (HIV) is important. Traditionally this measurement has been calculated by multiplying the percent of lymphocytes that are CD4+ T cells (from flow cytometry) and the number of lymphocytes per microliter of blood (from hematology mea
Balancing sexual partnerships in an age and activity stratified model of HIV transmission in heterosexual populations.: IMA J Math Appl Med Biol. 1994;11(3):161-92. Unique Identifier : AIDSLINE MED/95123186; Garnett GP; Anderson RM; Parasite Epidemiology Research Group, Imperial College, London,; UK.; A mathematical model of the transmission dynamics of HIV-1 in a heterosexual population stratified by age, sex, and sexual activity (defined by rates of sexual partner acquisition) is presented. The model represents an extension of previous studies with a special focus on patterns of mixing or contact between sexual a
HTLV-I antibody screening in donated blood and thalassemic patients.: J Med Assoc Thai. 1993 Oct;76 Suppl 2:103-5. Unique Identifier : AIDSLINE MED/95123281; Chiewsilp P; Iamsilp W; Hathirat P; Department of Pathology, Faculty of Medicine, Ramathibodi; Hospital, Mahidol University, Bangkok, Thailand.; The HTLV-I antibody screening by passive partial agglutination test, Serodia HTLV-I (Fuji-rebio Inc) was performed in a total of 1,225 male and 468 female blood donors from September 1992 to March 1993. In addition, a total of 64 multitransfused thalassemic patients were also studied. All of the sera from donors and p
Transmission of HIV infection by seronegative blood in Thailand.: J Med Assoc Thai. 1993 Oct;76 Suppl 2:106-13. Unique Identifier : AIDSLINE MED/95123282; Isarangkura P; Chiewsilp P; Tanprasert S; Nuchprayoon C; Department of Pediatrics, Faculty of Medicine, Ramathibodi; Hospital, Mahidol University, Bangkok, Thailand.; In Thailand , the prevalence of HIV infection in the general population and in donor blood (DB) has sharply increased since 1987. The HIV seropositive rate in DB was increased from 0.0065 per cent in 1987 to 0.95 per cent in 1993 (150 times in 6 years). Heterosexual transmission i
Disseminated Burkitt's lymphoma in a child with AIDS.: J Med Assoc Thai. 1993 Oct;76 Suppl 2:222-4. Unique Identifier : AIDSLINE MED/95123302; Sirinavin S; Hathirat P; Isarangkura P; Chuansumrit A; Division of Infectious Disease, Faculty of Medicine, Ramathibodi; Hospital, Mahidol University, Bangkok, Thailand.; Rarity of HIV-associated disseminated lymphomas in children initiated this report. The patient was an 18-month-old girl who had a history of chronic cervical lymphadenopathy since 6 months of age. She was first seen because of rapid enlargement of an inguinal lymphnode. The bone marrow aspirate was compatible with Bur
Imaging the adult brain.: J Neurol Neurosurg Psychiatry. 1995 Jan;58(1):7-21. Unique Identifier : AIDSLINE MED/95123378; Moseley I; Lysholm Department of Radiology, National Hospital for Neurology; and Neurosurgery, London, UK.
Legal concerns related to workers with HIV or AIDS.: J Nurs Adm. 1995 Jan;25(1):17-8. Unique Identifier : AIDSLINE MED/95123516; Blouin AS; Brent NJ; Ernst & Young Health Care Consulting, Chicago, IL.
HLA-DR antigen expression and lymphocyte subsets in transitional cell carcinoma of the urinary bladder. An immunohistological study on frozen sections.: J Pathol. 1994 Nov;174(3):183-9. Unique Identifier : AIDSLINE MED/95123572; Ioachim-Velogianni E; Stavropoulos NE; Kitsiou E; Stefanaki S; Agnantis NJ; Department of Pathology, University of Ioannina, Medical School,; Greece.; Lymphocyte subpopulations (B cells, CD4, CD8), interleukin-20 receptors ( IL-2 ), monocytes/macrophages (Leu M5), and HLA-DR antigen expression were studied immunohistochemically on frozen sections from 38 bladder cancer specimens. T cells predominated over B cells in al
Candida-associated palatal papillary hyperplasia in HIV infection.: J Oral Pathol Med. 1994 Oct;23(9):403-5. Unique Identifier : AIDSLINE MED/95123625; Reichart PA; Schmidt-Westhausen A; Samaranayake LP; Philipsen HP; Abteilung fur Zahnarztliche Chirurgie/Oralchirurgie, Freie; Universitat Berlin, Germany.; Oral Candida infections may appear in many guises, especially in HIV-infected individuals. Whereas the pseudomembranous and the erythematous forms of oral candidiasis are the most frequently encountered in such patients, there appear to be further clinical variants of this disease. This paper describes seven dentate h
Donor pool may rise as screening blood test falls [news]: JAMA. 1995 Feb 1;273(5):366. Unique Identifier : AIDSLINE MED/95123698; Marwick C
Maternal-fetal transmission of HIV-1 [letter; comment]: JAMA. 1995 Feb 1;273(5):377. Unique Identifier : AIDSLINE MED/95123709; Sarkar S
Lymphokine-activated killer cell function of lymphocytes from regional lymph nodes in patients with gastric carcinoma.: J Surg Oncol. 1995 Jan;58(1):44-9. Unique Identifier : AIDSLINE MED/95123913; Arinaga S; Karimine N; Nanbara S; Inoue H; Nakashima H; Ueo H; Akiyoshi T; Department of Surgery, Kyushu University, Beppu, Japan.; Lymphokine-activated killer (LAK) cells generated by culture of regional lymph node cells (LNC) with interleukin 2 (IL 2) for 4 and 11 days were examined for their functional capabilities in comparison with those of peripheral blood mononuclear cells (PBM) in 25 patients with gastric carcinoma. The cytotoxic activity
Radioactive body politics: AIDS as nuclear text.: Lit Med. 1994 Fall;13(2):229-42. Unique Identifier : AIDSLINE MED/95123978; Larabee A
Clinical aspects of psychoneuroimmunology [news] [published erratum appears in Lancet 1995 Mar 25;345(8952):804]: Lancet. 1995 Jan 21;345(8943):183-4. Unique Identifier : AIDSLINE MED/95124030; Goodkin K; Fletcher MA; Cohen N
Living wills in HIV infection and AIDS [letter; comment]: Lancet. 1995 Jan 21;345(8943):195. Unique Identifier : AIDSLINE MED/95124046; Noble G
Control of nosocomial transmission of multidrug-resistant Mycobacterium tuberculosis among healthcare workers and HIV-infected patients.: Lancet. 1995 Jan 28;345(8944):235-40. Unique Identifier : AIDSLINE MED/95124076; Wenger PN; Otten J; Breeden A; Orfas D; Beck-Sague CM; Jarvis WR; Hospital Infections Program, National Center for Infectious; Disease, Centers for Disease Control and Prevention, Atlanta, GA; 30333.; From 1988 to 1990, an outbreak of multidrug-resistant tuberculosis (MDR-TB) among patients, and an increased number of tuberculin-skin-test conversions among healthcare workers, occurred on the HIV ward of Jackson Memorial Hospital, Miami, Florida, USA. Measures similar to those subsequently recommended in the 1990 Ce
Lowering the US hurdles for AIDS drugs [news]: Lancet. 1995 Jan 28;345(8944):247-8. Unique Identifier : AIDSLINE MED/95124080; Rowe PM
Screening blood [news]: Lancet. 1995 Jan 28;345(8944):249. Unique Identifier : AIDSLINE MED/95124081; Rowe PM
Regimen containing short-term rifampicin for pulmonary tuberculosis in HIV-infection [letter; comment]: Lancet. 1995 Jan 28;345(8944):264-5. Unique Identifier : AIDSLINE MED/95124113; Harries AD; Mbewe LN; Maher D; Salaniponi FM; Nyangulu DS
Rifabutin prophylaxis against Mycobacterium avium complex infection [letter; comment]: Lancet. 1995 Jan 28;345(8944):265. Unique Identifier : AIDSLINE MED/95124114; Nightingale SD
Increased hematopoietic toxicity following administration of interferon-a with combination dideoxynucleoside therapy (zidovudine plus ddI) administered in normal mice.: Life Sci. 1995;56(3):PL71-81. Unique Identifier : AIDSLINE MED/95124132; Gallicchio VS; Scott KW; Hughes NK; Tse KF; Gaines H; Kirk PR; Birch NJ; Division of Hematology/Oncology, University of Kentucky,; Lexington 40536-0084.; Because of the urgency to develop drugs which will effectively combat HIV infection, many combination therapies which have proved effective against HIV in vitro have undergone, or are undergoing clinical trial. Unfortunately many of drugs are being used without rigorous and exhaustive preclinical evaluation to assess
Correlation between anti-V3 peptide and neutralizing antibodies in plasma from HIV-1 infected individuals resident in Brazil.: Mem Inst Oswaldo Cruz. 1994 Jan-Mar;89(1):113-4. Unique Identifier : AIDSLINE MED/95124189; Bongertz V; Morgado MG; Galvao-Castro B; Wigzell H; Hendry RM; Departamento de Immunologia, Instituto Oswaldo Cruz, Rio de; Janeiro, Brasil.
Parameter estimates from nonlinear models.: Methods Enzymol. 1994;240:23-36. Unique Identifier : AIDSLINE MED/95124217; Watts DG; Department of Mathematics and Statistics, Queen's University,; Kingston, Ontario, Canada.
Determining confidence intervals for parameters derived from analysis of equilibrium analytical ultracentrifugation data.: Methods Enzymol. 1994;240:459-78. Unique Identifier : AIDSLINE MED/95124227; Brooks I; Watts DG; Soneson KK; Hensley P; Department of Macromolecular Sciences, SmithKline Beecham; Pharmaceuticals, King of Prussia, Pennsylvania 19406.; In the above discussion, we have introduced the profiling approach of Bates and Watts. It is an easy to implement, empirical approach to the determination of confidence intervals for parameters in nonlinear models. We have applied the approach to the analysis of equilibrium sedimentation data and have demonstrated tha
Dental clinic fined for refusing to treat AIDS patient [news]: Minn Med. 1994 Dec;77(12):38. Unique Identifier : AIDSLINE MED/95124268
Transcriptional regulation of the mouse alpha A-crystallin gene: activation dependent on a cyclic AMP-responsive element (DE1/CRE) and a Pax-6-binding site.: Mol Cell Biol. 1995 Feb;15(2):653-60. Unique Identifier : AIDSLINE MED/95124323; Cvekl A; Kashanchi F; Sax CM; Brady JN; Piatigorsky J; Laboratory of Molecular and Developmental Biology, National Eye; Institute, Bethesda, Maryland 20892-2730.; Two cis-acting promoter elements (-108 to -100 and -49 to -33) of the mouse alpha A-crystallin gene, which is highly expressed in the ocular lens, were studied. Here we show that DE1 (-108 to 100; 5 TGACGGTG3 ), which resembles the consensus cyclic AMP (cAMP)-responsive element sequence (CRE; 5 TGACGT[A/C][A/G]3 ), be
How helpful is thoracic paraspinal EMG in HAM/TSP?: Muscle Nerve. 1995 Feb;18(2):248-50. Unique Identifier : AIDSLINE MED/95124397; Arimura K; Arimura Y; Moritoyo H; Tokimura Y; Takenaga S; Sonoda Y; Yamanaka H; Nakagawa M; Izumo S; Osame M; Third Department of Internal Medicine, Faculty of Medicine,; Kagoshima University, Japan.
Management of occupational exposures to blood-borne viruses.: N Engl J Med. 1995 Feb 16;332(7):444-51. Unique Identifier : AIDSLINE MED/95124435; Gerberding JL; Department of Medicine (Infectious Diseases), University of; California, San Francisco.
Knowledge of drugs for myocardial infarction: generalists versus specialists [letter; comment]: N Engl J Med. 1995 Feb 16;332(7):473; discussion 473-4. Unique Identifier : AIDSLINE MED/95124450; Markson LE; Turner BJ
Detection of Strongyloides stercoralis in the cerebrospinal fluid of a patient with acquired immunodeficiency syndrome.: Neurology. 1995 Jan;45(1):193-4. Unique Identifier : AIDSLINE MED/95124544; Takayanagui OM; Lofrano MM; Araugo MB; Chimelli L; Department of Neurology, Faculty of Medicine of Ribeirao Preto,; Sao Paulo University, Brazil.; We report a case of Strongyloides stercoralis hyperinfection syndrome in a patient with acquired immunodeficiency syndrome with CNS involvement who died despite prompt institution of thiabendazole.
Assessment of MRI criteria for MS in Japanese MS and HAM/TSP.: Neurology. 1995 Jan;45(1):30-3. Unique Identifier : AIDSLINE MED/95124557; Kuroda Y; Matsui M; Yukitake M; Kurohara K; Takashima H; Takashima Y; Endo C; Kato A; Mihara F; Department of Internal Medicine (Division of Neurology), Saga; Medical School, Japan.; We evaluated the usefulness of the MRI criteria for multiple sclerosis (MS) proposed by Paty et al and Fazekas et al in 36 Japanese MS patients, using HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) as the control. Although 30 of 36 HAM/TSP patients had multiple white matter lesions on T2-weighte
Glutamate production by cultured microglia: differences between rat and mouse, enhancement by lipopolysaccharide and lack effect of HIV coat protein gp120 and depolarizing agents.: Neurosci Lett. 1994 Sep 12;178(2):184-9. Unique Identifier : AIDSLINE MED/95124628; Patrizio M; Levi G; Laboratory of Pathophysiology, Istituto Superiore di Sanita,; Rome, Italy.; Glutamate release from rat and mouse microglia subcultures grown in a serum-free medium was substantially greater in the presence than in the absence of a physiological concentration of glutamine (0.5 mM). Mouse microglia produced and released more glutamate than rat microglia. Glutamate accumulation in the medium inc
AIDS newsletter [news]: N Z Dent J. 1994 Dec;90(402):162-3. Unique Identifier : AIDSLINE MED/95124659
[The host-opportunistic protozoa system. The dissemination of Pneumocystis infection in white rats under the influence of drug-induced and biological immunosuppression]: Parazitologiia. 1994 May-Jun;28(3):230-5. Unique Identifier : AIDSLINE MED/95124732; Lysenko AIa; Lavdovskaia MV; Kovalenko FP; Chernov IuV; Strelkova MV; The main purpose of the present study is the investigation of relationships of Pneumocystis carinii with the organism of white rat Wistar, which is natural carrier of this parasite. The series of experiments has shown that the immunosuppressor Tricort-40 (corticosteroid of prolonged activity) in a short time reactivat
Prevalence of HIV infections among patients attending a Parisian anonymous testing center between 1988 and 1993.: Pathol Biol (Paris). 1994 May;42(5):530-2. Unique Identifier : AIDSLINE MED/95124772; Mazeron MC; Cervoni J; Alain S; Honderlick P; Raskine L; Chassany O; Caulin C; Sanson-Le Pors MJ; Service de Bacteriologie-Virologie, Hopital Lariboisiere,; Universite Paris VII, France.; The prevalence of HIV infection was assessed among 15,611 consecutive patients attending a Parisian anonymous testing center from April 1988 to June 1993. Sera (17,910) were tested for the presence of anti-HIV antibodies using two different enzyme-linked immunosorbent assays. Seropositivity was verified by Western blo
[Vasculitis and neurologic manifestations related to HTLV-1]: Presse Med. 1994 Oct 15;23(31):1421-5. Unique Identifier : AIDSLINE MED/95124916; Vernant JC; Smadja D; Deforge-Lasseur C; Cabre P; Buisson G; Neisson-Vernant C; Desgranges C; Service de Neurologie, Hopital de jour (CNV), Fort-de-France.; OBJECTIVES: The most common neurological picture associated with HTLV-1 infection is a slowly progressive spastic paraplegia often involving nerve and muscle inflammation. We report here six cases of inflammatory vasculitis of the nervous system observed among HTLV-1 infected patients. METHODS: HTLV-1 infection was di
[Atypical mycobacterial infections (see comments)]: Presse Med. 1994 Oct 22;23(32):1483-8. Unique Identifier : AIDSLINE MED/95124931; Dautzenberg B; Mercat A; Service de Pneumologie, Groupe hospitalier Pitie-Salpetriere,; Paris.; Infrequent and forgotten before the advent of the acquired immune deficiency syndrome (AIDS), non-tuberculous mycobacterial infections are now often encountered, predominately in patients positive for the human immune deficiency virus (HIV). In non-AIDS patients, Mycobacterium kansasii, M. avium and M. xenopi are the
[Early reappearance of varicella-zona virus in the cerebrospinal fluid after treatment with foscarnet in AIDS (letter)]: Presse Med. 1994 Nov 5;23(34):1583. Unique Identifier : AIDSLINE MED/95124960; Marlier S; De Jaureguiberry JP; Drouet A; Muzellec Y; Jaubert D
[Have the incidence and resistance of tuberculosis increased? Epidemiologic follow-up based on diseases confirmed by culture]: Pneumologie. 1994 Nov;48(11):803-8. Unique Identifier : AIDSLINE MED/95124965; Schneider C; Lasch C; Brade V; Abt. fur Medizinische Mikrobiologie, Johann Wolfgang; Goethe-Universitat, Frankfurt am Main.; The unexpected increase in the incidence of tuberculosis in many industrialized countries, which was recorded in Germany for the first time in 1992, provided the incentive for this retrospective analysis over the past 13 years of the epidemiology and resistance situation for Tbc i
Microtube batch protein crystallization: applications to human immunodeficiency virus type 2 (HIV-2) protease and human renin.: Proteins. 1994 Sep;20(1):98-102. Unique Identifier : AIDSLINE MED/95124990; Pav S; Lubbe K; Do F; Lamarre D; Pargellis C; Tong L; Department of Biochemistry, Boehringer Ingelheim Pharmaceuticals,; Inc., Ridgefield, Connecticut 06877.; For therapeutically relevant targets, the evaluation of enzymes in complex with their inhibitors by cocrystallization and high resolution structural analysis has become a vital component of structure-driven drug design and development. Two approaches, hanging drop vapor diffusion and a novel microtube batch method, we
The emerging histories of AIDS: three successive paradigms.: Pubbl Stn Zool Napoli [II]. 1993;15(3):459-87. Unique Identifier : AIDSLINE MED/95125185; Fee E; Krieger N; Johns Hopkins University, School of Hygiene and Public Health,; Baltimore, MD 21205.; Thinking of AIDS as an emerging disease inevitably raises questions of comparison. In the United States , we see three main phases in understanding AIDS, with each having very different implications for health and social policy. In the first, AIDS was conceived of as an epidemic disea
Giant ulcers of the esophagus in patients with human immunodeficiency virus: clinical, radiographic, and pathologic findings.: Radiology. 1995 Feb;194(2):447-51. Unique Identifier : AIDSLINE MED/95125220; Sor S; Levine MS; Kowalski TE; Laufer I; Rubesin SE; Herlinger H; Department of Radiology, University of Pennslyvania, Philadelphia; 19104.; PURPOSE: To determine the causes of giant esophageal ulcers in patients with human immunodeficiency virus (HIV) and whether clinical or radiographic criteria can be used to differentiate the infections that cause these ulcers. MATERIALS AND METHODS: From January 1990 through December 1993, giant esophageal ulcers ( >
[Virology: diagnosis or screening?]: Rev Med Brux. 1994 Nov-Dec;15(6):355-8. Unique Identifier : AIDSLINE MED/95125333; Thiry L; Institut Pasteur, Bruxelles.; Andre Dachy is a sensitive clinician as well as a microbiologist who knows about hidden meanings of laboratory tests. Pediatrics was enriched by his dual interest in observation of the children and of the microbes which threaten them. As time went by, Dachy s interest for social medicine grew. Thus, it is justified to
[The child exposed to the human immunodeficiency virus]: Rev Med Brux. 1994 Nov-Dec;15(6):387-92. Unique Identifier : AIDSLINE MED/95125339; Levy J; Service de Pediatrie, Hopital Saint-Pierre, Bruxelles.; The care of the child exposed to human immunodeficiency virus extends beyond the treatment of the medical complications of the illness. It begins during the pregnancy by an individualised decision regarding the indication of a prophylactic intervention to reduce the risk of mother-to-child transmission of the virus, i
[Epidemiological expression of other sexually transmitted diseases among AIDS patients]: Rev Saude Publica. 1994 Apr;28(2):93-9. Unique Identifier : AIDSLINE MED/95125359; Gir E; Duarte G; Martinez R; Moriya TM; Figueiredo JF; da Costa JC; Machado AA; Departamento de Enfermagem Geral e Especializada da Escola de; Enfermagem de Ribeirao Preto da Universidade de Sao Paulo,; Brasil.; This study was carried out in order to estimate the frequency of other sexually transmitted diseases (STD) among AIDS patients and to identify their epidemiological association and possible relations to the groups most exposed to the virus. The data were collected from the medical case histories and the STD were ident
Subpopulations of T lymphocytes in the peripheral blood, dermal lesions and lymph nodes of post kala-azar dermal leishmaniasis patients.: Scand J Immunol. 1995 Jan;41(1):11-7. Unique Identifier : AIDSLINE MED/95125391; Ghosh MK; Nandy A; Addy M; Maitra TK; Ghose AC; Department of Microbiology, Bose Institute, Calcutta, India.; Distribution of different subpopulations of T cells in the dermal lesions, lymph nodes and peripheral blood of post kala-azar dermal lesihmaniasis (PKADL) patients was studied by using appropriate phenotypic markers for CD2+, CD4+ and CD8+ cells. Histopathological studies of skin lesions showed marginal to massive inf
Enhancement of infectivity of a non-syncytium inducing HIV-1 by sCD4 and by human antibodies that neutralize syncytium inducing HIV-1.: Scand J Immunol. 1995 Jan;41(1):18-22. Unique Identifier : AIDSLINE MED/95125392; Schutten M; Andeweg AC; Bosch ML; Osterhaus AD; Erasmus University Rotterdam, Institute of Virology, Rotterdam,; The Netherlands.; Enhancement of virus infectivity after sCD4 treatment has been documented for SIVagm and HIV-2. It has been suggested that a similar phenomenon may play a role in HIV-1 infection. In the present study we have analysed biological activities of virus neutralizing polyclonal and monoclonal human antibodies and of sCD4, t
The Duesberg phenomenon: Duesberg and other voices [letter; comment] [see comments]: Science. 1995 Jan 20;267(5196):313-4; discussion 316. Unique Identifier : AIDSLINE MED/95125427; Duesberg PH
The Duesberg phenomenon: Duesberg and other voices [letter; comment]: Science. 1995 Jan 20;267(5196):314. Unique Identifier : AIDSLINE MED/95125428; Delaney M
The Duesberg phenomenon: Duesberg and other voices [letter; comment]: Science. 1995 Jan 20;267(5196):314-5. Unique Identifier : AIDSLINE MED/95125429; Cline FA Jr
The Duesberg phenomenon: Duesberg and other voices [letter; comment]: Science. 1995 Jan 20;267(5196):315. Unique Identifier : AIDSLINE MED/95125430; Birkett N
Finis to MicroGeneSys saga? [news]: Science. 1995 Jan 20;267(5196):335. Unique Identifier : AIDSLINE MED/95125440
HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy [see comments]: Science. 1995 Jan 27;267(5197):483-9. Unique Identifier : AIDSLINE MED/95125459; Coffin JM; Department of Molecular Biology and Microbiology, Tufts; University School of Medicine, Boston, MA 02111.; Several recent reports indicate that the long, clinically latent phase that characterizes human immunodeficiency virus (HIV) infection of humans is not a period of viral inactivity, but an active process in which cells are being infected and dying at a high rate and in large numbers. These results lead to a simple ste
Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators.: Science. 1995 Jan 27;267(5197):531-6. Unique Identifier : AIDSLINE GENBANK/U18062; Chiang CM; Roeder RG; Laboratory of Biochemistry and Molecular Biology, Rockefeller; University, New York, NY 10021.; TFIID is a multisubunit protein complex comprised of the TATA-binding protein (TBP) and multiple TBP-associated factors (TAFs). The TAFs in TFIID are essential for activator-dependent transcription. The cloning of a complementary DNA encoding a human TFIID TAF, TAFII55, that has no known homolog in Drosophila TFIID is
TH2 downregulation of macrophage HIV-1 replication [letter; comment]: Science. 1995 Jan 27;267(5197):538-9. Unique Identifier : AIDSLINE MED/95125467; Montaner LJ; Gordon S
Case report 865. Bacillary angiomatosis.: Skeletal Radiol. 1994 Oct;23(7):569-71. Unique Identifier : AIDSLINE MED/95125501; Standiford KN; Emery CD; Schiffman RJ; Department of Radiology, Pennsylvania Hospital, Philadelphia; 19107.; A case of bacillary angiomatosis was presented, characterized by subcutaneous lesions, systemic symptoms, and impressive periostitis which initially masked a small cortical lytic lesion. Review of the reported cases suggests that a diagnosis of bacillary angiomatosis should b
AIDS related attitudes and sexual practices of the Jakarta WARIA (male transvestites).: Southeast Asian J Trop Med Public Health. 1994 Mar;25(1):102-6. Unique Identifier : AIDSLINE MED/95125510; Lubis I; Master J; Bambang M; Papilaya A; Anthony RL; AIDS and STD Prevention Program, Indonesian Public Health; Association, Jakarta.; As part of a community based educational campaign to convey the risk of HIV infection and AIDS to commercial sex workers in Jakarta, over 600 male transvestites (WARIA) were questioned about their sexual behavior patterns and their knowledge and attitude towards HIV infection and AIDS. Most expressed a genuine fear ab
Cyclospora sp causing diarrhea in man.: Southeast Asian J Trop Med Public Health. 1994 Mar;25(1):221-3. Unique Identifier : AIDSLINE MED/95125534; Sinniah B; Rajeswari B; Johari S; Ramakrishnan K; Yusoff SW; Rohela M; Department of Parasitology, Faculty of Medicine, University of; Malaya.
Isolation of HIV-1 from Filipino commercial sex workers (CSWs).: Southeast Asian J Trop Med Public Health. 1994 Mar;25(1):96-101. Unique Identifier : AIDSLINE MED/95125548; Torres CA; Hayes CG; Manaloto CR; Gonzales VL; Anthony RL; US Naval Medical Research Unit No. 2 Detachment, Manila, Republic; of the Philippines.; Peripheral blood mononuclear cells (PBMC) from 36 HIV-1 antibody positive Filipino female commercial sex workers (CSWs) were co-cultivated at a 1:1 ratio with phytohemagglutinin-P activated PBMC from healthy, HIV-1 antibody negative donors. After 3-18 (mean 7.2) days of incubation at 37 degrees C in 5% CO2, 29 culture
Lymphoproliferative disorders in non-AIDS-associated Kaposi's sarcoma. The Johannesburg Hospital experience, 1980-1992.: S Afr Med J. 1994 Aug;84(8 Pt 1):484-8. Unique Identifier : AIDSLINE MED/95125597; Stein ME; Spencer D; Dansey R; Perner Y; Gunther K; Bezwoda WR; Department of Medical Oncology and Haematology, Johannesburg; Hospital.; The association of the non-AIDS-related, classic form of Kaposi s sarcoma (KS) with secondary malignancies, especially lymphoproliferative disorders, has frequently been noted. However, in endemic African-type KS, such an association has been reported only rarely. A review of 62 non-AIDS-related cases of KS treated an
HIV-2 and its neurological manifestations.: S Afr Med J. 1994 Aug;84(8 Pt 1):503-5. Unique Identifier : AIDSLINE MED/95125602; Rolfe M; Royal Victoria Hospital, Banjul, The Gambia, West Africa.; The human immunodeficiency virus type 2 (HIV-2) produces a similar spectrum of illness as HIV-1, including AIDS, and is clinically indistinguishable. There is evidence that it is less pathogenic, with a longer natural history. HIV-2 infection is endemic in West Africa, especially in the former Portuguese and French co
Time-course of toxicity of reactive sulfonamide metabolites.: Toxicology. 1995 Jan 6;95(1-3):141-6. Unique Identifier : AIDSLINE MED/95125705; Rieder MJ; Krause R; Bird IA; Child Health Research Institute/J.P. Robarts Research Institute,; Department of Paediatrics, University of Western Ontario, London,; Canada.; It has been suggested, on the basis of work in cell-free systems, that sulfonamide hydroxy-lamines are metabolized to nitroso metabolites which may be the proximate toxins mediating sulfonamide hypersensitivity reactions. We performed time-course experiments investigating the toxicity of the hydroxylamine and nitroso
Time course of detection of viral and serologic markers preceding human immunodeficiency virus type 1 seroconversion: implications for screening of blood and tissue donors.: Transfusion. 1995 Feb;35(2):91-7. Unique Identifier : AIDSLINE MED/95125745; Busch MP; Lee LL; Satten GA; Henrard DR; Farzadegan H; Nelson KE; Read S; Dodd RY; Petersen LR; Irwin Memorial Blood Centers, San Francisco, California.; BACKGROUND: Almost all human immunodeficiency virus (HIV) transmission via blood or tissues that has occurred since anti-HIV screening was implemented in 1985 is traceable to blood given after infection but before antibody seroconversion, a time that is referred to as the window period. In this study, the performance
Long-term follow-up of blood donors with indeterminate human immunodeficiency virus type 1 results on Western blot.: Transfusion. 1995 Feb;35(2):98-102. Unique Identifier : AIDSLINE MED/95125746; Jackson JB; Hanson MR; Johnson GM; Spahlinger TG; Polesky HF; Bowman RJ; Institute of Pathology, Case Western Reserve University School of; Medicine, Cleveland, Ohio.; BACKGROUND: At present, tens of thousands of United States blood donors who are at low risk for human immunodeficiency virus type 1 (HIV-1) infection are indefinitely deferred. These persons are repeatably reactive for HIV-1 antibody in enzyme immunoassay (EIA) and are indeterminate in
The hearing-aid battery: a hazard to elderly patients.: Age Ageing. 1994 Sep;23(5):425-6. Unique Identifier : AIDSLINE MED/95126024; Strachan DR; Kenny H; Hope GA; Ear, Nose and Throat Department, York District Hospital.; Owing to the severity of its corrosive effects, an alkaline hearing-aid battery in the external auditory meatus is an otological emergency. This report emphasizes the particular risk to confused elderly patients and points out that a delay in diagnosis is common. Aetiology, clinical features and treatment are discusse
[Acquired immunodeficiency syndrome and ophthalmology (editorial)]: Nippon Ganka Gakkai Zasshi. 1994 Nov;98(11):1047-8. Unique Identifier : AIDSLINE MED/95126027; Usui M; Department of Ophthalmology, Tokyo Medical College.
[Rapidly progressive outer retinal necrosis in a patient with acquired immunodeficiency syndrome]: Nippon Ganka Gakkai Zasshi. 1994 Nov;98(11):1141-6. Unique Identifier : AIDSLINE MED/95126044; Oshitari K; Arimoto H; Suzuki S; Oguchi Y; Department of Ophthalmology, Keio University School of Medicine,; Tokyo, Japan.; We report a case of rapidly progressive varicella zoster virus retinitis, which is distinct from acute retinal necrosis syndrome. The patient was a 52-year-old male and suffered acquired immunodeficiency syndrome. Two months after the varicella zoster dermatitis in the distribution of the first division of the left tr
[Early cytomegalovirus retinitis]: Nippon Ganka Gakkai Zasshi. 1994 Nov;98(11):1147-52. Unique Identifier : AIDSLINE MED/95126045; Nagata Y; Obata H; Fujino Y; Matsumoto S; Mochizuki M; Oka S; Kimura S; Shimada K; Okada T; Wakabayashi T; Department of Ophthalmology, University of Tokyo School of; Medicine, Japan.; We report the clinical course of cytomegalovirus ( CMV ) retinitis associated with acquired immunodeficiency syndrome (AIDS) from the initial onset. The patient was a 40-year-old human immunodeficiency virus antibody-positive m
Tumor necrosis factor and AIDS [letter; comment]: Am J Clin Nutr. 1995 Jan;61(1):161-2. Unique Identifier : AIDSLINE MED/95126063; Roubenoff R
Sudden unexpected death in a male homosexual cohort.: Am J Forensic Med Pathol. 1994 Sep;15(3):247-50. Unique Identifier : AIDSLINE MED/95126091; Ndimbie OK; Perper JA; Kingsley L; Harty L; Winkelstein A; Department of Pathology, University of Pittsburgh, PA.; There has been considerable debate as to the risk of suicide, accidents, and homicide in populations at high risk for HIV infection. The purpose of the present investigation was to determine the incidence of sudden and unexpected deaths in a well-defined cohort of homosexual and bisexual men prospectively studied sinc
Aerosolized pentamidine prophylaxis of Pneumocystis carinii pneumonia in HIV-infected patients [letter; comment]: Am J Med. 1995 Jan;98(1):101-2. Unique Identifier : AIDSLINE MED/95126148; Domingo P; Ris J; Serra J; Puig M; Martinez E; Sambeat MA
Avoiding false-negative results for HTLV-II using new serological assays [letter; comment]: Am J Med. 1995 Jan;98(1):103. Unique Identifier : AIDSLINE MED/95126150; Soriano V; Gutierrez M; Tuset C; Martinez-Zapico R; Calderon E; Gonzalez-Lahoz J
Didanosine-induced hypertriglyceridemia [letter; comment]: Am J Med. 1995 Jan;98(1):103. Unique Identifier : AIDSLINE MED/95126151; Tal A; Dall L
Fever, cough, and dyspnea in a 38-year-old man with acquired immunodeficiency syndrome [clinical conference]: Am J Med. 1995 Jan;98(1):85-94. Unique Identifier : AIDSLINE MED/95126162
My Own Country.: Am J Med. 1995 Jan;98(1):97-8. Unique Identifier : AIDSLINE MED/95126164; Van Peenen HJ
Comparisons of risk factors for HIV-1 infection in Jefferson and Mobile County, Alabama.: Am J Med Sci. 1995 Jan;309(1):1-4. Unique Identifier : AIDSLINE MED/95126188; Elliott M; Lee J; Hoff C; Ramsey KM; de Vivo V; King A; Holmes R; Eichold BH; Department of Sociology & Anthropology, University of South; Alabama, Mobile 36640-0130.; A study of the Alabama state AIDS database was conducted to determine whether differences exist in demographic and risk characteristics between patients with HIV-1 in Jefferson and Mobile County. The authors found that the age distribution of patients with HIV-1, the percent of those having AIDS, and the percent of th
Case report: inhalation therapy of paromomycin is effective for respiratory infection and hypoxia by cryptosporidium with AIDS.: Am J Med Sci. 1995 Jan;309(1):60-2. Unique Identifier : AIDSLINE MED/95126196; Mohri H; Fujita H; Asakura Y; Katoh K; Okamoto R; Tanabe J; Harano H; Noguchi T; Inayama Y; Amano T; et al; First Department of Internal Medicine, Yokohama City University; School of Medicine, Japan.; A 24-year-old man with AIDS and hemophilia A had intractable diarrhea and fever. Upon examination of stool and of a sigmoidal biopsy specimen, cryptosporidium was revealed. Approximately 2 months after admission, respiratory infection with hypoxia due to cryptosporidium developed. Paromomycin inhalation was effective
Poor correlation between reactive syphilis serology and human immunodeficiency virus testing among potential cornea donors [see comments]: Am J Ophthalmol. 1995 Jan;119(1):1-6. Unique Identifier : AIDSLINE MED/95126214; Goldberg MA; Laycock KA; Kinard S; Wang H; Pepose JS; Department of Ophthalmology and Visual Sciences, Washington; University School of Medicine, St. Louis, Missouri 63110.; PURPOSE: The current practice in which eye banks screen cornea donors for syphilis is based mainly on the potential utility of positive syphilis serology as a surrogate marker for human immunodeficiency virus-1 (HIV-1) infection. We examined the correlation between positive syphilis and HIV-1 serologies within the pot
Human T-cell lymphotropic virus type I-associated uveitis in an African American.: Am J Ophthalmol. 1995 Jan;119(1):104-5. Unique Identifier : AIDSLINE MED/95126218; Beilke MA; Section of Infectious Diseases, Tulane University Medical School,; New Orleans, LA 70112.; PURPOSE/METHODS: In an African American woman with the human T-cell lymphotropic virus type I associated with uveitis, clinical and ocular findings were correlated with detection of viral genome by polymerase chain reaction, and by viral antigen detection in cultured peripheral blood mononuclear cells. RESULTS/CONCLUS
Corneal lipidosis in patients with the acquired immunodeficiency syndrome [see comments]: Am J Ophthalmol. 1995 Jan;119(1):14-9. Unique Identifier : AIDSLINE MED/95126225; Wilhelmus KR; Keener MJ; Jones DB; Font RL; Department of Ophthalmology, Baylor College of Medicine, Houston,; TX.; PURPOSE: Certain drugs bind to anionic phospholipids of lysosomal membranes and produce progressive intracellular accumulation of lamellar inclusions. We studied two patients treated for opportunistic infections associated with the acquired immunodeficiency syndrome (AIDS), who developed bilateral ocular surface chang
Screening corneas for human immunodeficiency virus type 1 proviral DNA by polymerase chain reaction [see comments]: Am J Ophthalmol. 1995 Jan;119(1):7-13. Unique Identifier : AIDSLINE MED/95126233; Garcia-Ferrer FJ; Laycock KA; Buerger DG; Flowers BE; Foos RY; Pepose JS; Department of Ophthalmology and Visual Science, Washington; University School of Medicine, St. Louis, Missouri 63110.; PURPOSE: We evaluated the sensitivity of the polymerase chain reaction as a technique to directly screen potential donor corneas for human immunodeficiency virus type 1 (HIV-1) proviral DNA. METHODS: DNA from the central 8.0-mm cornea, limbal cornea, aqueous humor, and retina from 22 eyes of 11 cadavers seropositive f
Syphilis, serologic testing, and the setting of standards for eye banks [editorial; comment]: Am J Ophthalmol. 1995 Jan;119(1):93-5. Unique Identifier : AIDSLINE MED/95126237; Mannis MJ; Sugar J
Classification of HIV infection and disease in women from Rwanda. Evaluation of the World Health Organization HIV staging system and recommended modifications.: Ann Intern Med. 1995 Feb 15;122(4):262-70. Unique Identifier : AIDSLINE MED/95126306; Lifson AR; Allen S; Wolf W; Serufilira A; Kantarama G; Lindan CP; Hudes ES; Nsengumuremyi F; Taelman H; Batungwanayo J; University of California, San Francisco.; OBJECTIVE: To develop a human immunodeficiency virus (HIV) staging system for sub-Saharan Africa on the basis of an evaluation of the World Health Organization (WHO) system and predictors of mortality. DESIGN: Prospective cohort study with 4 years of follow-up. SETTING: Kigali,
Bleeding injuries in professional football: estimating the risk for HIV transmission.: Ann Intern Med. 1995 Feb 15;122(4):273-4. Unique Identifier : AIDSLINE MED/95126307; Brown LS Jr; Drotman DP; Chu A; Brown CL Jr; Knowlan D; Addiction Research and Treatment Corporation, Brooklyn, New York.; OBJECTIVE: To determine the risk for bleeding injuries in professional football and to estimate the risk for transmission of the human immunodeficiency virus (HIV) through such injuries. DESIGN: A prospective, observational study. PARTICIPANTS: Professional football players from 11 teams of the National Football Leagu
Transmission of blood-borne pathogens during sports: risk and prevention [see comments]: Ann Intern Med. 1995 Feb 15;122(4):283-5. Unique Identifier : AIDSLINE MED/95126310; Mast EE; Goodman RA; Bond WW; Favero MS; Drotman DP; Centers for Disease Control and Prevention, Atlanta, Georgia.; Publicity about human immunodeficiency virus (HIV) infection in athletes has focused attention on the potential for transmission of blood-borne pathogens during sports and athletic competitions. Existing information suggests that the potential risk for such transmission is extremely low and that the principal risks at
Atovaquone for Pneumocystis carinii pneumonia [letter; comment]: Ann Intern Med. 1995 Feb 15;122(4):314; discussion 314-5. Unique Identifier : AIDSLINE MED/95126316; Lederman MM; van der Horst C
Atovaquone for Pneumocystis carinii pneumonia [letter; comment]: Ann Intern Med. 1995 Feb 15;122(4):314; discussion 314-5. Unique Identifier : AIDSLINE MED/95126317; Stoeckle M; Tennenberg A
[AIDS: ethical drift]: Ann Med Psychol (Paris). 1994 Nov;152(9):627-30. Unique Identifier : AIDSLINE MED/95126337; Koupernik C; AIDS is not merely a new viral disease, or an unprecedented variety of acquired immune deficiency. It is an STD equally transmitted by blood and birth, it has for the last eleven years, baffled all the assault attempted by the most competent researchers, it is lethal in the vas majority of cases, it has reached a plan
[Biological tests in the hospital and human rights: concerning HIV serology]: Ann Med Psychol (Paris). 1994 Nov;152(9):630-3. Unique Identifier : AIDSLINE MED/95126338; Prevost X; Garrabe J; Institut National M. Riviere.; The spreading of a new pathology, highly involved in the medical and psychological fields, A.I.D.S., combined with the present biological achievements make the different hospital services face many ethical problems. Following the various stages in the making of H.I.V. serologies, the authors intend to describe behavio
Endotoxins, cytokines, and neuroimmune networks with special reference to HIV infection.: Ann N Y Acad Sci. 1994 Nov 25;741:174-84. Unique Identifier : AIDSLINE MED/95126350; Jirillo E; Covelli V; Maffione AB; Greco B; Pece S; Fumarola D; Antonaci S; De Simone C; Facolta di Medicina, Universita di Bari, Italy.
Prolonged asymptomatic states in HIV-seropositive persons with fewer than 50 CD4+ T cells per MM3. Psychoneuroimmunologic findings.: Ann N Y Acad Sci. 1994 Nov 25;741:185-90. Unique Identifier : AIDSLINE MED/95126351; Solomon GF; Benton D; Harker JO; Bonavida B; Fletcher MA; Department of Psychiatry & Biobehavioral Sciences, UCLA School of; Medicine.
Steroid effects on central neurons and implications for psychiatric and neurological disorders.: Ann N Y Acad Sci. 1994 Nov 30;746:345-59; discussion 359-61. Unique Identifier : AIDSLINE MED/95126437; Holsboer F; Grasser A; Friess E; Wiedemann K; Max Planck Institute of Psychiatry Clinical Institute, Munich,; Germany.; Acute and chronic stress as well as a number of psychiatric and neurological disorders are accompanied by profound disturbances of the HPA system. These neuroendocrine alterations act back on the central nervous tissue mainly via corticosteroids-affecting glucocorticoid and mineralocorticoid receptors. The major concl
AIDS-associated mycoplasmas.: Annu Rev Microbiol. 1994;48:687-712. Unique Identifier : AIDSLINE MED/95126575; Blanchard A; Montagnier L; Department of AIDS and Retroviruses, Institut Pasteur, Paris,; France.; Previously, we hypothesized that mycoplasmas could act as cofactors accelerating the progression of HIV disease. In the present paper, we review the current knowledge on three mycoplasmas (Mycoplasma fermentans, M. penetrans, and M. pirum) that have been implicated as these putative cofactors. All three mycoplasmas ha
Advanced Technologies in Research, Diagnosis and Treatment of AIDS and in Oncology. Proceedings of an international workshop. Naples, October 21-22, 1993.: Antibiot Chemother. 1994;46:1-169. Unique Identifier : AIDSLINE MED/95126580
Perspectives in research, diagnosis and treatment of AIDS and in oncology.: Antibiot Chemother. 1994;46:1-4. Unique Identifier : AIDSLINE MED/95126581; Giraldo G; Division of Viral Oncology, Istituto Nazionale Tumori Fondazione; G. Pascale, Naples, Italy.
Role of HIV as cofactor in HPV oncogenesis: in vitro evidences of virus interactions.: Antibiot Chemother. 1994;46:102-9. Unique Identifier : AIDSLINE MED/95126582; Buonaguro FM; Tornesello ML; Buonaguro L; Del Gaudio E; Beth-Giraldo E; Giraldo G; Division of Viral Oncology, Istituto Nazionale Tumori Fondazione; G. Pascale, Naples, Italy.
Molecular pathogenesis of AIDS-related lymphomas.: Antibiot Chemother. 1994;46:117-24. Unique Identifier : AIDSLINE MED/95126584; Gaidano G; Dalla-Favera R; Department of Pathology, College of Physicians and Surgeons,; Columbia University, New York, N.Y.
Detection and characterization of human T-lymphotropic viruses.: Antibiot Chemother. 1994;46:125-33. Unique Identifier : AIDSLINE MED/95126585; Calabro ML; Favero A; Chieco-Bianchi L; Institute of Oncology, University of Padua, Italy.
Convergent infections: human papillomavirus and human immunodeficiency virus.: Antibiot Chemother. 1994;46:134-49. Unique Identifier : AIDSLINE MED/95126586; Fisher SG; Gissmann L; Department of Obstetrics and Gynecology, Loyola University; Medical Center, Maywood, Ill.
Biological phenotypes of HIV-1 in pathogenesis and transmission.: Antibiot Chemother. 1994;46:18-24. Unique Identifier : AIDSLINE MED/95126588; Fenyo EM; Fiore J; Karlsson A; Albert J; Scarlatti G; Department of Microbiology and Tumor Biology, Karolinska; Institute, Stockholm, Sweden.
Human monoclonal antibodies for passive immunotherapy of HIV-1.: Antibiot Chemother. 1994;46:25-37. Unique Identifier : AIDSLINE MED/95126589; Katinger H; Institut fur Angewandte Mikrobiologie, Universitat fur; Bodenkultur, Wien, Osterreich.
Human monoclonal antibodies to HIV-1 define synergistic activities leading to enhanced neutralization.: Antibiot Chemother. 1994;46:38-47. Unique Identifier : AIDSLINE MED/95126590; Zolla-Pazner S; Laal S; Burda S; Buchbinder A; Laboratory Service, New York Veterans Affairs Medical Center.
Polyvalent, recombinant HIV-1 virus-like particles: novel HIV-1 vaccine strategies.: Antibiot Chemother. 1994;46:48-61. Unique Identifier : AIDSLINE MED/95126591; Wagner R; Deml L; Wolf H; Institut fur medizinische Mikrobiologie, Regensburg, BRD.
Pediatric HIV-1 infection: advances and perspectives in diagnosis and prognosis.: Antibiot Chemother. 1994;46:5-17. Unique Identifier : AIDSLINE MED/95126592; De Rossi A; Ometto L; Zanotto C; Salvatori F; Masiero S; Mammano F; Chieco-Bianchi L; Institute of Oncology, University of Padua, Italy.
Role of HIV-1 Tat in the pathogenesis of AIDS-associated Kaposi's sarcoma.: Antibiot Chemother. 1994;46:62-72. Unique Identifier : AIDSLINE MED/95126593; Buonaguro L; Buonaguro FM; Tornesello ML; Beth-Giraldo E; Del Gaudio E; Ensoli B; Giraldo G; Division of Viral Oncology, Istituto Nazionale Tumori Fondazione; G. Pascale, Naples, Italy.
Regulation of PDGF-B and PDGF receptor expression in the pathogenesis of Kaposi's sarcoma in AIDS.: Antibiot Chemother. 1994;46:73-87. Unique Identifier : AIDSLINE MED/95126594; Pistritto G; Ventura L; Mores N; Lacal PM; D'Onofrio C; Department of Experimental Medicine and Biochemical Sciences,; University of Rome Tor Vergata, Italy.
Human immunodeficiency virus and the Gianotti-Crosti syndrome [letter; comment]: Arch Dermatol. 1995 Jan;131(1):108-9. Unique Identifier : AIDSLINE MED/95126644; Stratte EG; Esterly NB
Polymerase chain reaction fails to incriminate exogenous retroviruses HTLV-I and HIV-1 in rheumatological diseases although a minority of sera cross react with retroviral antigens.: Ann Rheum Dis. 1994 Nov;53(11):749-54. Unique Identifier : AIDSLINE MED/95126699; Nelson PN; Lever AM; Bruckner FE; Isenberg DA; Kessaris N; Hay FC; Division of Immunology, St George's Hospital Medical School,; London, United Kingdom.; OBJECTIVES--To investigate the presence of antibodies to HTLV and HIV retroviral antigens in the rheumatological diseases rheumatoid arthritis (RA), polymyositis/dermatomyositis (PM/DM), primary Sjogren s syndrome (pSS), and systemic lupus erythematosus (SLE), and to use polymerase chain reaction (PCR) to seek these e
The Cambridge dilemma [letter; comment]: Ann Rheum Dis. 1994 Nov;53(11):780-1. Unique Identifier : AIDSLINE MED/95126706; Elling P; Elling H; Olsson AT
[Studies on 1,4-naphthoquinones. 23. 2-3-Halogen-2-3-nitrophenyljuglone derivatives, synthesis and cytotoxic properties]: Arch Pharm (Weinheim). 1994 Oct;327(10):627-30. Unique Identifier : AIDSLINE MED/95126764; Wurm G; Gurka HJ; Institut fur Pharmazie, Freien Universitat Berlin.; Radical arylation of 1,4-naphthoquinones is possible by oxidative decarboxylation of 2- and 4-nitrobenzoic acid. With 2- and 3-halogenojuglone derivatives the 4-nitrophenyl compounds 10-13 are prepared in good, the 2-nitrophenyl analogues 14-17 only in poor yields. All compounds are inactive against the virus types HS
Synthesis and antiviral evaluation of hydantoin analogues of AZT.: Arch Pharm (Weinheim). 1994 Oct;327(10):653-5. Unique Identifier : AIDSLINE MED/95126767; el-Barbary AA; Khodair AI; Pedersen EB; Department of Chemistry, Odense University, Denmark.; 3 -Azidonucleosides 4 have been synthesized by condensation of silylated (Z)-5-ethylidenehydantoin and (Z)-5-benzylidenehydantoin with methyl 3-azido-5-O-tert-butyldiphenylsilyl-2,3-dideoxy-D-erythro-pento furanoside (3). The nucleosides 4 were deblocked on treatment with tetrabutylammonium fluoride. The ethylidene gr
Spatial association of HIV-1 tat protein and the nucleolar transport protein B23 in stably transfected Jurkat T-cells.: Arch Virol. 1994;139(1-2):133-54. Unique Identifier : AIDSLINE MED/95126773; Marasco WA; Szilvay AM; Kalland KH; Helland DG; Reyes HM; Walter RJ; Division of Human Retrovirology, Dana-Farber Cancer Institute,; Harvard Medical School, Boston, Massachusetts.; The human immunodeficiency virus (HIV-1) encodes a transactivator protein, the product of the tat gene (tat), which is essential for virus replication. In this study, immunogold electron microscopy was used in a stably transfected Jurkat T-cell line that constitutively expresses HIV-1 tat protein to determine the subc
Analysis of long-term viral expression in CEM cells persistently infected with non syncytium-inducing HIV-1 strains.: Arch Virol. 1994;139(1-2):155-72. Unique Identifier : AIDSLINE MED/95126774; Yelle J; Morisset R; Thibodeau L; Centre de recherche en virologie, Institut Armand-Frappier,; Laval, Quebec, Canada.; CEM cells were infected with three HIV-1 non syncytium-inducing (NSI) strains obtained from AIDS patients or seropositive individuals. The surviving cells were followed for several months in the persistently infected cultures designated 65870/CEM, 65871/CEM and 3929/CEM, and analyzed for virus expression using light a
Biological and pharmacokinetic properties of a novel immunoglobulin-CD4 fusion protein.: Arch Virol. 1994;139(1-2):189-96. Unique Identifier : AIDSLINE MED/95126777; Lyczak JB; Morrison SL; Department of Microbiology and Molecular Genetics, University of; California, Los Angeles.; We report a CD4-immunoglobulin fusion protein in which the first two extracellular domains of human CD4 replace the Fc region of the immunoglobulin. When co-expressed with a gene encoding an immunoglobulin light chain, the protein was covalently assembled into a form having an M(r) consistent with that expected for tw
Phosphorothioate oligonucleotides inhibit the replication of lentiviruses and type D retroviruses, but not that of type C retroviruses [published erratum appears in Arch Virol 1995;140(4):809]: Arch Virol. 1994;139(1-2):97-109. Unique Identifier : AIDSLINE MED/95126788; Archambault D; Stein CA; Cohen JS; Universite du Quebec a Montreal, Departement des Sciences; Biologiques, Canada.; Phosphorothioate analogs of oligodeoxynucleotides at a concentration of 2 microM protected Himalayan tahr cells from infection by caprine arthritis encephalitis virus (CAEV) and equine dermis cells from infection by equine infectious anemia virus (EIAV). The characteristics of this inhibition against these lentiviruse
[A study on subpopulation of helper T cells in chronic inflammatory demyelinating polyneuropathy]: Arerugi. 1994 Oct;43(10):1270-6. Unique Identifier : AIDSLINE MED/95126794; Inoue A; Iwahashi T; Koh CS; Yanagisawa N; Department of Medicine (Neurology) Shinshu University School of; Medicine.; Chronic inflammatory demyelinating polyneuropathy (CIDP) is thought to be an inflammatory autoimmune disease against peripheral myelin. Recently several animal models have suggested that preferential activation of Th1 cell response is central to the pathogenesis of this disease. We studied the function of CD4 positive
[Hemiballismus as initial manifestation of acquired immunodeficiency syndrome: a case report]: Arq Neuropsiquiatr. 1994 Jun;52(2):263-5. Unique Identifier : AIDSLINE MED/95126830; Tedrus GM; Albertin MC; Fonseca LC; Departamento de Neuropsiquiatria, Faculdade de Ciencias Medicas,; Pontificia Universidade Catolica de Campinas (PUCCAMP), Brasil.; There are few descriptions of movement disorders as an initial presentation of acquired immunodeficiency syndrome (AIDS). The authors report the case of a 54-year-old man who presented with hemiballismus of gradual onset. The computed axial tomographic scan showed a deep seated enhancing lesion with mass effect. Inves
Correlation between computed tomographic brain scan abnormalities and neuropsychological function in children with symptomatic human immunodeficiency virus disease.: Arch Neurol. 1995 Jan;52(1):39-44. Unique Identifier : AIDSLINE MED/95126845; Brouwers P; DeCarli C; Civitello L; Moss H; Wolters P; Pizzo P; Pediatric Branch, National Cancer Institute, Bethesda, Md.; OBJECTIVE: To evaluate the clinical significance of computed tomographic brain scan abnormalities observed in children with symptomatic human immunodeficiency virus disease. PATIENTS: Eighty-seven previously untreated children with symptomatic human immunodeficiency virus type 1 disease. METHODS: General levels of cog
Cerebrospinal fluid treponemal antibodies in untreated early syphilis.: Arch Neurol. 1995 Jan;52(1):68-72. Unique Identifier : AIDSLINE MED/95126849; Marra CM; Critchlow CW; Hook EW 3rd; Collier AC; Lukehart SA; Department of Medicine, University of Washington, Seattle.; OBJECTIVE: Examine prevalence and diagnostic utility of cerebrospinal fluid (CSF) treponemal antibodies in early syphilis. DESIGN: Comparison study. SETTING: Sexually transmitted diseases clinic. PATIENTS: Forty patients with untreated early syphilis who underwent lumbar puncture. Fifteen were human immunodeficiency v
Cytomegalovirus retinitis in HIV-infected patients with elevated CD4+ counts [letter]: Arch Ophthalmol. 1995 Jan;113(1):18. Unique Identifier : AIDSLINE MED/95126860; Fekrat S; Dunn JP; Lee D; Miller T; Jabs DA
Intraocular sustained drug release devices [editorial]: Arch Ophthalmol. 1995 Jan;113(1):25-6. Unique Identifier : AIDSLINE MED/95126863; Irvine AR
The predictive value of cytomegalovirus retinitis for cytomegalovirus encephalitis in acquired immunodeficiency syndrome.: Arch Ophthalmol. 1995 Jan;113(1):89-95. Unique Identifier : AIDSLINE MED/95126872; Bylsma SS; Achim CL; Wiley CA; Gonzalez C; Kuppermann BD; Berry C; Freeman WR; Department of Ophthalmology, University of California-San Diego,; La Jolla.; Cytomegalovirus ( CMV ) infection of the brain, optic nerves, and retinas from 47 consecutive autopsies of patients with acquired immunodeficiency syndrome (AIDS) were examined. Immunocytochemistry demonstrated CMV infection in 11 (23%) brains, two (2%) of 94 opti
Induction of resistance to 1-beta-D-arabinofuranosylcytosine in human H9 cell line by simian immunodeficiency virus.: Biochem Biophys Res Commun. 1995 Jan 17;206(2):486-91. Unique Identifier : AIDSLINE MED/95126944; Yusa K; Oh-hara T; Tsuruo T; Cancer Chemotherapy Center, Japanese Foundation for Cancer; Research, Tokyo.; We examined drug sensitivity of human T cell acute lymphoblastic leukemia H9 cells chronically infected with simian immunodeficiency virus (SIVmac) and found that the retrovirus-infected H9 cells showed 8.2-fold resistance to 1-beta-D-arabinofuranosylcytosine (Ara-C). In the infected cells, Ara-CTP levels decreased to
[Synthesis and comparative analysis of antigenic activity of peptides from hypervariable region V3 of human immunodeficiency virus I gp120 surface glycoprotein]: Bioorg Khim. 1994 Oct;20(10):1070-9. Unique Identifier : AIDSLINE MED/95126991; Semiletov IuA; Rzhaninova AA; Garaev MM; A set of peptides (amino acid positions 10-23) corresponding to seven most widely spread variants of the gp120 V3 domain in the HIV-infected population of South Russia were prepared by the solid-phase synthesis. A laboratory variant of the indirect enzyme-linked immunosorbent assay
[4'-Branched nucleosides. II. Synthesis of 4'-hydroxymethyl derivatives of 2',3'-anhydronucleosides of the ribo- and lyxo-series]: Bioorg Khim. 1994 Oct;20(10):1114-24. Unique Identifier : AIDSLINE MED/95126993; Surzhikov SA; A general synthetic method for 4 -hydroxymethyl-2 ,3 -anhydronucleosides from 1,2-O-isopropylidene-4-hydroxymethyl-alpha-D-xylofuranose is described. The condensation of 1,2-di-O-acetyl-3-O-methanesulphonyl-4-benzoyloxymethyl-5-O- benzoyl-D-xylofuranose with trimethylsilyl derivatives of N6-benzoyladenine and N2-palmi
Efficacy trials of AIDS vaccines: how science can inform ethics [editorial]: Curr Opin Immunol. 1994 Oct;6(5):691-7. Unique Identifier : AIDSLINE MED/95127105; Fast PE; Mathieson BJ; Schultz AM
Cytokines and the Th1/Th2 paradigm in transplantation.: Curr Opin Immunol. 1994 Oct;6(5):757-64. Unique Identifier : AIDSLINE MED/95127114; Nickerson P; Steurer W; Steiger J; Zheng X; Steele AW; Strom TB; Harvard Medical School, Beth Israel Hospital, Boston.; With studies elucidating the cytokine programs associated with T-cell activation, allograft rejection and tolerance induction, the Th1/Th2 paradigm has become a unifying model to explain the observed cytokine profiles. The proof that these cytokines mediate allograft tolerance, however, is at best indirect. More recen
AIDS: endocrinologic and metabolic considerations [editorial]: Ann Med. 1994 Oct;26(5):321-3. Unique Identifier : AIDSLINE MED/95127177; Grinspoon S
Proliferation inhibition and CD4/CD8 thymocyte subset skewing by in vivo exposure of C57BL/6 mice to Ah receptor-binding 3,3',4,4'-tetrachlorobiphenyl.: Exp Clin Immunogenet. 1994;11(2-3):75-85. Unique Identifier : AIDSLINE MED/95127259; Esser C; Lai Z; Gleichmann E; Medical Institute of Environmental Hygiene, Dusseldorf, Germany.; 3,3 ,4,4 -Tetrachlorobiphenyl (TCB) and other Ah receptor-binding xenobiotics lead to thymus atrophy and immunosuppression, the former possibly causing the latter. In order to better understand the TCB-induced events in the murine thymus, we analyzed the effects of TCB on the proliferation capacity and maturation kine
Phylogenesis and genetic complexity of the nonhuman primate retroviridae.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1047-60. Unique Identifier : AIDSLINE MED/95127286; Franchini G; Reitz MS Jr; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.; The three known groups of nonhuman primate retroviruses (simian immunodeficiency virus, simian T cell lymphotropic/leukemic virus type I, and simian foamy virus) are thought to have equivalent human counterparts. This is clearly the case with human immunodeficiency virus types 1 and 2, the causative agents of acquired
Inhibition of alloreactive cytotoxic T cell activity by HIV-positive sera: potential role of circulating soluble HLA class I molecules.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1061-4. Unique Identifier : AIDSLINE MED/95127287; Puppo F; Brenci S; Montinaro E; Lanza L; Contini P; Scudeletti M; Indiveri F; Department of Internal Medicine, University of Genoa, Italy.
Binding of glycoprotein 120 and peptides from the HIV-1 envelope by autoantibodies in mice with experimentally induced systemic lupus erythematosus and in patients with the disease.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1071-7. Unique Identifier : AIDSLINE MED/95127289; Bermas BL; Petri M; Berzofsky JA; Waisman A; Shearer GM; Mozes E; Experimental Immunology Branch, National Cancer Institute, NIH,; Bethesda, Maryland 20892.; Systemic lupus erythematosus (SLE) and infection with the human immunodeficiency virus type 1 (HIV) are diseases that are characterized by immune dysregulation and autoantibody production. In this article we identify and characterize IgG antibodies from mice with SLE and SLE patients that bind HIV gp120 and HIV envelo
Enhancement of HIV type 1 infectivity in vitro by capsular polysaccharide of Cryptococcus neoformans and Haemophilus influenzae.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1079-87. Unique Identifier : AIDSLINE MED/95127290; Pettoello-Mantovani M; Casadevall A; Smarnworawong P; Goldstein H; Department of Pediatrics, Albert Einstein College of Medicine,; Bronx, New York 10461.; High concentrations of the cryptococcal capsular polysaccharide (CCP) are present in the serum, cerebrospinal fluid or both in the majority of AIDS patients infected with Cryptococcus neoformans. Because the prognosis of AIDS patients infected with cryptococcus is poor, we investigated whether the presence of CCP enha
Infectious virus with reduced cytopathogenicity resulting from persistent infection of normal lung fibroblasts by HIV type 1 strains.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1089-95. Unique Identifier : AIDSLINE MED/95127291; Dolei A; Serra C; Arca MV; Tilocca F; Riva E; Antonelli G; Dianzani F; Toniolo A; Institute of Microbiology and Virology, University of Sassari,; Italy.; We asked whether HIV-1 had the capacity to establish a persistent infection of cultured human diploid fibroblasts. Human strains of normal diploid embryo lung fibroblasts were infected with HIV-1 of the HTLV-IIIB and HIV-1P1 strains. Infection was followed over time, to analyze HIV expression. Virus production (intra-
Differential priming to programmed cell death of superantigen-reactive lymphocytes of HIV patients.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1097-103. Unique Identifier : AIDSLINE MED/95127292; Gorla R; Imberti L; Prati E; Brugnoni D; Caligaris S; Cattaneo R; Albertini A; Primi D; Clinical Immunology Units, Spedali Civili of Brescia, Italy.; Programmed cell death or apoptosis has been shown to play a central role in CD4+ T cell depletion following HIV infection. Because most apoptotic signals are delivered through T cell receptor stimulation, we investigated whether T cell depletion in AIDS is a stochastic phenomenon or if it preferentially affects T cell
Familial transmission and minimal sequence variability of human T-lymphotropic virus type I (HTLV-I) in Zaire.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1135-42. Unique Identifier : AIDSLINE MED/95127296; Liu HF; Vandamme AM; Kazadi K; Carton H; Desmyter J; Goubau P; Rega Institute for Medical Research and University Hospitals,; Katholieke Universiteit Leuven, Belgium.; Our group previously reported a strong familial clustering of HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Zaire , suggesting a familial transmission of the virus together with the presence of cofactors. In the present study among 84 relatives of 16 HTLV-I
Viral variability and serum antibody response in a laboratory worker infected with HIV type 1 (HTLV type IIIB).: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1143-55. Unique Identifier : AIDSLINE GENBANK/U12055; Reitz MS Jr; Hall L; Robert-Guroff M; Lautenberger J; Hahn BM; Shaw GM; Kong LI; Weiss SH; Waters D; Gallo RC; et al; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.; Molecular clones of HIV-1 were obtained from isolates cultured from peripheral blood mononuclear cells (PBMCs) and directly from uncultured PBMCs from a laboratory worker accidentally infected with the HIV-1 laboratory strain, HIV-1(HTLV-IIIB). Envelope sequences corresponding to the first 752 amino acids of HIV-1(HTL
Endemic transmission of HTLV type II among Kayapo Indians of Brazil.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1165-71. Unique Identifier : AIDSLINE MED/95127299; Black FL; Biggar RJ; Neel JV; Maloney EM; Waters DJ; Department of Epidemiology and Public Health, Yale University; School of Medicine, New Haven, Connecticut 06520-8034.; Serological studies on 926 blood samples from 703 Brazilian Kayapo (Cayapo) Indians showed, by conventional definition of HTLV seropositivity, a 28% prevalence of human T lymphotropic virus (HTLV) infection, the highest yet reported. Immunoblot (WB) and SYNTH-EIA patterns indicate that the predominant infecting agent
Cutaneous disease resembling mycosis fungoides in HIV-infected patients whose skin and blood cells also harbor proviral HTLV type I.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1173-7. Unique Identifier : AIDSLINE MED/95127300; Zucker-Franklin D; Pancake BA; Friedman-Kien AE; New York University Medical Center, New York 10016.; Two homosexual HIV-infected patients with lymphocyte counts of
Feline immunodeficiency virus infection of macrophages: in vitro and in vivo inhibition by dideoxycytidine-5'-triphosphate-loaded erythrocytes.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1179-86. Unique Identifier : AIDSLINE MED/95127301; Magnani M; Rossi L; Fraternale A; Silvotti L; Quintavalla F; Piedimonte G; Matteucci D; Baldinotti F; Bendinelli M; Istituto di Chimica Biologica, Universita di Urbino, Italy.; Although HIV-1 and other mammalian lentiviruses infect macrophages, they are not cytopathic. Consequently, these infected long-lived cells serve as major virus reservoirs with a key role in the propagation of the virus throughout the body as well as in the pathogenesis of AIDS. Furthermore, well-differentiated macroph
HIV type 1 V3 sequence diversity in contact-traced Swedish couples at the time of sexual transmission.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1187-9. Unique Identifier : AIDSLINE GENBANK/U10950; Furuta Y; Bergstrom T; Norkrans G; Horal P; Department of Clinical Virology, Goteborg University, Sweden.
Phylogenetic analysis of a new chimpanzee lentivirus SIVcpz-gab2 from a wild-captured chimpanzee from Gabon.: AIDS Res Hum Retroviruses. 1994 Sep;10(9):1191-2. Unique Identifier : AIDSLINE GENBANK/U11495; Janssens W; Fransen K; Peeters M; Heyndrickx L; Motte J; Bedjabaga L; Delaporte E; Piot P; van der Groen G; Department of Infection and Immunity, Institute of Tropical; Medicine, Antwerp, Belgium.
Transfer of dideoxyinosine across the human isolated placenta.: Br J Clin Pharmacol. 1994 Sep;38(3):237-42. Unique Identifier : AIDSLINE MED/95127427; Henderson GI; Perez AB; Yang Y; Hamby RL; Schenken RS; Schenker S; Department of Medicine, University of Texas Health Science Center; at San Antonio 78284-7878.; 1. Dideoxyinosine (ddI) has recently been approved for the treatment of patients with HIV infection. As increasing numbers of such patients are pregnant, we wished to define the rate and mechanism(s) of ddI transfer by the placenta to the foetus. Using isolated single perfused human term placental cotyledons, the drug
Preliminary results of HIV screening in sentinel facilities in Romania.: Rev Roum Virol. 1993 Jul-Dec;44(3-4):171-3. Unique Identifier : AIDSLINE MED/95127473; Cernescu C; Popescu A; Tirdei G; Alexandrescu R; Ruta SM; Stefan S. Nicolau Institute of Virology, Bucharest, Romania.; In the first months of 1994, 393 patients (random consecutive clinic attenders) from three sentinel clinics were tested for anti-V3 loop antibodies in ELISA with a branched synthetic peptide reproducing eight copies of full V3 sequence. Compared with a commercial HIV 1/2 ELISA kit the sensitivity of anti-V3 assay was
Relevance of the reactivity of HIV 1 positive sera with synthetic peptides for understanding antigenic differences between circulating strains.: Rev Roum Virol. 1993 Jul-Dec;44(3-4):175-86. Unique Identifier : AIDSLINE MED/95127474; Cernescu C; Ruta SM; Stefan S. Nicolau, Institute of Virology, Bucharest, Romania.; Several problems have arisen concerning the detection methodology of sources and chains of HIV transmission based on molecular and antigenic relatedness of HIV isolates. Great progress in mapping virus genome or provirus, especially in identifying the changes in the env gene provides interesting data for molecular epi
Neuroophthalmological examination in children with AIDS.: Rev Roum Virol. 1993 Jul-Dec;44(3-4):187-93. Unique Identifier : AIDSLINE MED/95127475; Constantinescu AF; Ruta SM; Constantinescu SN; Cernescu C; Department of Ophthalmology, Witting Hospital, Bueharest,; Romania.; Evaluation of HIV disease status includes physical examination (anthropomorphic measurements, neurological assessment, etc.) and laboratory examination. Consideration should be given to changes from baseline values, age adjusted normal values and the rapidity of changes. Here we compare results of neuroophthalmologic
Infection with human immunodeficiency viruses and human T-cell lymphotropic viruses in the same individuals in Nigeria.: Rev Roum Virol. 1993 Jul-Dec;44(3-4):233-6. Unique Identifier : AIDSLINE MED/95127481; Olaleye OD; Ekweozor CC; Department of Virology, College of Medicine, University College