Incidence of Kaposi's sarcoma (KS), non-Hodgkin's lymphoma (NHL), and other malignancies in a cohort of gay men with human immunodeficiency virus (HIV) infection (Meeting abstract).

Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

Incidence of Kaposi's sarcoma (KS), non-Hodgkin's lymphoma (NHL), and other malignancies in a cohort of gay men with human immunodeficiency virus (HIV) infection (Meeting abstract).

Proc Annu Meet Am Soc Clin Oncol; 13:A2 1994. Unique Identifier : AIDSLINE ICDB/94699998
Lyter D; Bryant J; Thackeray R; Zhao P; Rinaldo C; Kingsley L; Univ. of Pittsburgh, Div. of Medical Oncology, Pittsburgh, PA

Abstract: Between October 1, 1984 and November 15, 1993, 1199 gay men were followed by the Pitt Men's Study, the Pittsburgh component of the MACS, a study of the natural history of HIV infection. The cohort included 769 HIV seronegative (SN) participants and 430 who were either seropositive (SP) at enrollment or who seroconverted during the course of the study. Cancer incidence data were collected via semi-annual visits, phone interviews, medical records, and death certificates. 2344 person-years and 5708 person-years were contributed to the study by the SP and SN, respectively. In addition to 44 cases of KS in the SP and 14 NHL's (13 in SP and 1 in SN), malignancies that occurred are shown in a table. Age-adjusted rates were calculated for both groups and compared with rates for the general population (GP). There were no differences between the SN and the GP. Rates of KS and NHL in the SP were 400 and 73 times higher (respectively) as compared to the GP. The total number of other cancers was significantly increased in the SP versus the GP, due to an increased rate of testicular cancer. There were no significant increases in rates of Hodgkin's disease, skin cancer or cancer of the anus in the SP.

Keywords: Cohort Studies Cross-Sectional Studies Homosexuality/*STATISTICS & NUMER DATA Human HIV Infections/*EPIDEMIOLOGY Incidence Lymphoma, AIDS-Related/*EPIDEMIOLOGY Male Neoplasms/*EPIDEMIOLOGY Pennsylvania/EPIDEMIOLOGY Sarcoma, Kaposi's/*EPIDEMIOLOGY Skin Neoplasms/*EPIDEMIOLOGY ABSTRACT MULTICENTER STUDY

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