1994

Nutrition for persons with HIV infection. [videorecording]
[Michigan] : University of Michigan, c1991 1 videocassette (19 min., 23 sec.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9430598
Bridges T; Church MJ; Collins T
Clinical update on HIV infection : recorded at DDW 1994 in New Orleans. [sound recording]
[Thorofare, N.J.] : American Gastroenterology [i.e. Gastroenterological] Association, [1994] 1 sound cassette (90 min.) : analog (AGA clinical symposium) Unique Identifier : AIDSLINE AV/9435489
Controlling your risks : HIV in the research laboratory : a video. [videorecording]
[Bethesda, Md.] : Howard Hughes Medical Institute, c1994 1 videocassette (28 min.) : sd., col. with b&w ; 1/2 in Unique Identifier : AIDSLINE AV/9433966
Schumann W; Barkley WE; Martin MA
(Producer) Designed for laboratory workers at risk of occupational exposure to HIV, the video promotes laboratory safety and highlights the practices and equipment used to protect against HIV transmission in the research environment. Thoughts of several prominent researchers, including Harold Varmus and Tony Fauci,


AIDS : knowledge, attitudes, and sexual practices among Hispanics in Chicago : results of a 1988 city-wide survey : preliminary analyses.
Chicago : The Alliance, [1988] 107, [106] leaves : ill Unique Identifier : AIDSLINE CAT/9415120
A:five year medium term plan for the prevention and control of AIDS in Malawi : (1989-1993).
Lilongwe, Malawi : National AIDS Control Programme, Ministry of Health, [1989] 128 p. : ill Unique Identifier : AIDSLINE CAT/9405518
Recommendations for prevention of HIV transmission in health care settings.
Education Services. HIV/AIDS and Infectious Diseases [Olympia, Wash.?] : HIV/AIDS and Infectious Diseases, Office of Prevention and Education Services, Washington State Dept. of Health, [1990?] 25, x p (DOH Pub. ; 410-004) Unique Identifier : AIDSLINE CAT/9431422
Malawi, HIV treatment guidelines for adults and children : national guidelines.
[Malawi? : s.n., 1991] 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9414530
Dragon within the gates : the once and future AIDS epidemic. 1st ed.
New York : Carroll & Graf Publishers, 1992 272 p Unique Identifier : AIDSLINE CAT/9405648
Joseph SC
[Drogues illicites et attitudes face au SIDA : resultats d'une enquete epidemiologique realisee dans le Sud-Haute-Marne.]
Paris : INSERM, c1992 87 p. : ill (Analyses et prospective) Unique Identifier : AIDSLINE CAT/9407705
Choquet M
Getting to the point : HIV, drug abuse, and syringe exchange in the United States.
Denver, Colo. (1560 Broadway, Suite 700, Denver 80202) : National Conference of State Legislatures, 1992 17 p (State legislative report ; vol. 17, no. 14) Unique Identifier : AIDSLINE CAT/9405641
Hooker TA
Legal issues in pediatric HIV practice : a handbook for health care providers.
Newark, NJ : National Pediatric HIV Resource Center, [c1992] 1 v. (various pagings) Unique Identifier : AIDSLINE CAT/9415282
The:anarchist AIDS medical formulary : a guide to guerrilla immunology.
Berkeley, Calif. : North Atlantic Books, c1993 xv, 155 p. : ill Unique Identifier : AIDSLINE CAT/9423638
Caulfield CR; Goldberg B
HIV molecular organization, pathogenicity, and treatment.
Amsterdam ; New York : Elsevier, 1993 viii, 386 p. : ill Unique Identifier : AIDSLINE CAT/9423567
Morrow J; Haigwood NL
Sexuality, politics, and AIDS in Brazil : in another world?.
London ; Washington, D.C. : Falmer Press, 1993 xiv, 168 p (Social aspects of AIDS) Unique Identifier : AIDSLINE CAT/9417494
Daniel H; Parker RG
Sixth research project on AIDS : progress report : Orbetello (GR), 19-23 June 1993.
Roma : Ministerio della sanita, Istituto superiore di sanita, 1993 368 p. : ill (Rapporti ISTISAN, ISSN 0391-1675 ; ISTISAN 93/32) Unique Identifier : AIDSLINE CAT/9433707
AIDS and behavior : an integrated approach.
Washington, D.C. : National Academy Press, 1994 xvii, 338 p. : ill Unique Identifier : AIDSLINE CAT/9434637
Auerbach JG; Wypijewska C; Brodie HK; Mental Health Issues in AIDS Research
Treating AIDS with Chinese medicine.
Berkeley, Calif. : Pacific View Press, c1994 xx, 364 p Unique Identifier : AIDSLINE CAT/9431127
Ryan MK; Shattuck AD
Understanding the possible : policies for the prevention of HIV in South Africa.
Johannesburg : Centre for Health Policy, University of the Witwatersrand : Medical Research Council, [1994?] 27 p. : ill Unique Identifier : AIDSLINE CAT/9431805
Schneider H; Steinberg M; IJsselmuiden C
Dental management of patients with HIV.
Chicago : Quintessence Pub. Co., c1994 319 p. : ill Unique Identifier : AIDSLINE CAT/9435285
Glick M
HIV and your child.
Rockville, MD (Executive Office Center, Suite 501, 2101 E. Jefferson St., Rockville 20852) : U.S. Dept. of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, [1994] 21 p. : ill (Clinical practice guideline ; no. 7. Consumer guide) Unique Identifier : AIDSLINE CAT/9423491
HIV infection in women.
New York : Raven Press, c1995 xiv, 328 p. : ill Unique Identifier : AIDSLINE CAT/9434906
Minkoff HL; DeHovitz JA; Duerr A
Gynecologic oncology. 2nd ed.
Gynecologic Oncology. 2nd Ed. Coppleson M, ed. New York, Churchill Livingstone, 2 vol., 1525 p., 1992.. Unique Identifier : AIDSLINE ICDB/94696705
Anonymous; No affiliation given
Rapid advances in both scientific and clinical aspects of the specialty in the 10 yr since the 1st edition of Gynecologic Oncology mandated the present 2nd edition which, because of this growth, contains an additional 12 chapters. The bulk of the book deals in detail with the gynecologic malignancies, presenting clini


Regulation of transcription of the tax transgene and tax-induced genes in tumor cell lines of the LTR-tax transgenic mouse.
Diss Abstr Int [B]; 53(9):4501 1993. Unique Identifier : AIDSLINE ICDB/94690786
Fontes JD; Univ. of California, Davis
The LTR-tax transgenic mouse develops peripheral neurofibromas as its primary pathologic feature. An in vitro cell line (Px-1 cells) derived from one of these tumors provides an excellent model for the study of tax-driven neoplasia. Using these cells, the role of tax in the trans-activation of cellular genes and the t


Alternative dna structures in topoisomerase II-DNA interactions.
Diss Abstr Int [B]; 53(9):4481 1993. Unique Identifier : AIDSLINE ICDB/94690788
Howard MT; Univ. of North Carolina at Chapel Hill
The type II DNA topoisomerases are enzymes that can change the topological state of DNA. This is accomplished by passing DNA strands through each other via a transient break in the helix. The result of this reaction is to relax or introduce DNA supercoils and to resolve knotted or catenated DNAs. Topoisomerase activit


Dietary carotenoids, cigarette smoking and Kaposi's sarcoma in the San Francisco Men's Health Study.
Diss Abstr Int [B]; 53(9):4596 1993. Unique Identifier : AIDSLINE ICDB/94690808
Duncan DM; Univ. of California, Berkeley
This study utilized data from the San Francisco Men s Health Study (SFMHS) to explore the relationship between dietary intake and subsequent development of Kaposi s sarcoma (KS) in a cohort of men at high risk for acquired immunodeficiency syndrome (AIDS). The SFMHS is a prospective study observing the natural history


Sequence analysis of a viral gene found within the central nervous system of patients with human T-cell lymphotropic virus type I-associated disease.
Diss Abstr Int [B]; 53(10):5067 1993. Unique Identifier : AIDSLINE ICDB/94690940
Maroushek SR; Univ. of Minnesota
Human T-cell lymphotropic virus type I (HTLV-I) is a type C retrovirus endemic to portions of Japan , the Caribbean, Africa, South America, and the United States . Although infection with HTLV-I causes predominantly asymptomatic infections, HTLV-I is t


The epidemiology of hepatitis C virus transmission.
Diss Abstr Int [B]; 53(10):5160 1993. Unique Identifier : AIDSLINE ICDB/94690954
Osmond DH; Univ. of California, Berkeley
Hepatitis C virus (HCV) is a newly identified virus that is the most important agent of non-A non-B hepatitis and is associated with cirrhosis and hepatocellular carcinoma. HCV is readily transmitted intravenously by blood and blood products, but preliminary reports have disagreed about the importance of perinatal and


An epidemiological approach to the etiology of Hodgkin's disease.
Diss Abstr Int [C]; 54(2):506 1993. Unique Identifier : AIDSLINE ICDB/94696103
Merk KF; Karolinska Institutet, Sweden
In focus of this thesis were factors of potential importance for the development and outcome of Hodgkin s disease (HD), especially the cause of the immunodeficiency (ID) and its relation to HD. The epidemiological features of HD in Cuba and Sweden


Function of the human T-cell leukemia virus Rex response element in viral RNA processing.
Diss Abstr Int [B]; 53(12):6110 1993. Unique Identifier : AIDSLINE ICDB/94696128
Ahmed YF; Duke Univ.
The type I human T cell leukemia virus (HTLV-I) is the etiologic agent of an aggressive malignancy of human CD4+ T lymphocytes known as adult T cell leukemia. In addition to the gag, pol and env genes present in all replication-competent retroviruses, HTLV contains two additional regulatory genes tax and rex. The HTLV


Analysis of three distinct stages of replication in human retroviruses.
Diss Abstr Int [B]; 53(12):6113 1993. Unique Identifier : AIDSLINE ICDB/94696141
Hammes SR; Duke Univ.
The type 1 human immunodeficiency and human T-cell leukemia viruses (HIV-1 and HTLV-I, respectively) use many mechanisms at various stages throughout their life cycles to regulate replication. Three of these processes were examined in detail in order to better understand some of the complexities of this regulation. Th


Increased survival and development of lymphoma in murine immunodeficiency disease (MAIDS): effects of lithium and magnesium in vivo (Meeting abstract).
FASEB J; 7(4):A692 1993. Unique Identifier : AIDSLINE ICDB/94696889
Gallicchio VS; Cibull ML; Hughes NK; Tse KF; Univ. of Kentucky and Veterans Administration Medical Centers,; Lexington, KY 40536
Murine immunodeficiency disease (MAIDS) induced with LP-BM5 strain of MuLV is a disease that shows many similarities to human HIV-infection. Lithium (Li) influences many aspects of immunohematopoietic cellular proliferation and differentiation and is an antagonist to magnesium (Mg) dependent reactions. We describe her


Cationic liposomes for direct gene transfer in therapy of cancer and other diseases (Meeting abstract).
Gene Therapy for Neoplastic Diseases. June 26-29, 1993, Washington, DC, A5, 1993.. Unique Identifier : AIDSLINE ICDB/94698152
Huang L; Gao X; Farhood H; Son K; Dept. of Pharmacology, Univ. of Pittsburgh Sch. of Medicine,; Pittsburgh, PA
Cationic liposomes can mediate efficient delivery of DNA and DNA/protein complex to mammalian cells in vitro and in vivo. Cationic cholesterol derivatives mixed with phosphatidylethanolamine and sonicated to form small unilamellar vesicles can complex with DNA and mediate the entry into the cytosol from the endosome c


The retroviral life cycle and safety considerations for retroviral mediated gene therapy (Meeting abstract).
Gene Therapy for Neoplastic Diseases. June 26-29, 1993, Washington, DC, A7, 1993.. Unique Identifier : AIDSLINE ICDB/94698154
Boris-Lawrie K; Temin HM; McArdle Lab. for Cancer Res., Univ. of Wisconsin, Madison, WI
The life cycle of retroviruses makes them uniquely suited as vectors for gene therapy. Safety is the primary consideration when designing retroviral vectors and helper cells. Retroviral vectors used for gene therapy are based on simpler retroviruses (SRV), which do not cause disease in humans and ungulates. Retroviral


HTLV-I and -II natural history and disease associations (Meeting abstract).
International Association for Comparative Research on Leukemia and Related Diseases, 16th Symposium. July 11-16, 1993, Montreal, Quebec, Canada, A52, 1993.. Unique Identifier : AIDSLINE ICDB/94698650
Blattner WA; Viral Epidemiology Section, NCI, Bethesda, MD
In 1980 HTLV-I and in 1982 HTLV-II were isolated. Considerable progress has been gained in defining the natural history of HTLV-I, while for HTLV-II progress has been slow. Recent studies have helped to clarify mechanisms of virus transmission. Breast milk feeding is the major route for transmission of HTLV-I in the f


HTLV-I LTR 21 bp repeat-specific and neuroglial cell-specific DNA-protein complexes (Meeting abstract).
International Association for Comparative Research on Leukemia and Related Diseases, 16th Symposium. July 11-16, 1993, Montreal, Quebec, Canada, A54, 1993.. Unique Identifier : AIDSLINE ICDB/94698652
Tillmann M; Hinkel R; Wigdahl B; Dept. of Microbiology and Immunology, Pennsylvania State Univ.; Coll. of Medicine, Hershey, PA
Human T-cell leukemia virus type I (HTLV-I) is an etiologic agent of adult T-cell leukemia and a chronic neurologic disorder, tropical spastic paraparesis. An HTLV-I-encoded protein, Tax, is capable of transcriptionally trans-activating HTLV-I by interacting with specific sequences in the HTLV-I long terminal repeat (


Molecular and biochemical effects of novel drugs derived from photoactivated compounds for chemotherapy of leukemia (Meeting abstract).
International Association for Comparative Research on Leukemia and Related Diseases, 16th Symposium. July 11-16, 1993, Montreal, Quebec, Canada, A60, 1993.. Unique Identifier : AIDSLINE ICDB/94698657
Gulliya KS; Sharma RK; Wiggs RB; Baylor Univ. Medical Center, Baylor Res. Inst., 3812 Elm, Dallas,; TX 75226
The novel technology termed preactivation in which optical radiation is used to produce heretofore unknown therapeutic compounds has been reported (Gulliya et al, 1991). Because of this invention, photoactive compound-derived photoproducts can now be used, for the first time, for systemic therapy (independent of lig


A Phase I study of an angiogenesis inhibitor, TNP-470 (AGM-1470), administered to patients (pts) with HIV-associated Kaposi's sarcoma (KS) (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A8 1994. Unique Identifier : AIDSLINE ICDB/94600005
Pluda JM; Wyvill K; Figg WD; Whitcup SM; Lietzau J; Saville MW; Cohen R; Feigal E; Parks D; Foli A; et al; NCI, Bethesda, MD
The fumagillin analogue TNP-470 is a potent inhibitor of angiogenesis in vitro (Ingber, et al Nature 348, 555, 1990). Anti-tumor inhibitory activity in animal models has been shown to be dose- but not schedule-dependent. We have found that TNP-470 inhibits in vitro KS-derived spindle cell proliferation (Saville, et al


Novel combination chemotherapy for HIV-related non-Hodgkin's lymphoma (HIV-NHL) (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A13 1994. Unique Identifier : AIDSLINE ICDB/94600010
Sawka C; Shepherd F; Brandwein J; Berinstein N; Singer J; Canadian HIV Trials Network, Vancouver, Canada
Conventional-dose chemotherapy is poorly tolerated in HIV-NHL; even low-dose programs including our half-dose weekly drug program (Leukemia and Lymphoma 1992, 8:213-220) have been associated with significant febrile neutropenia rates. We designed a novel chemotherapy program to attempt to reduce this complication whil


A trial of Paclitaxel (TAXOL) in patients with HIV-associated Kaposi's sarcoma (KS) (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A20 1994. Unique Identifier : AIDSLINE ICDB/94600017
Saville MW; Lietzau J; Wilson W; Pluda J; Bailey J; Cohen R; Feigal E; Broder S; Yarchoan R; NCI, Bethesda, MD 20892
KS is a frequent cause of severe morbidity and death in patients with human immunodeficiency virus (HIV) infection. Current therapies are often poorly tolerated, and new drugs are needed for this condition. It has been observed that inhibitors of microtubule assembly are active against KS, and this led us to consider


Epidemiological, virological and clinicopathological data from 114 patients (pts) with Hodgkin's disease and HIV infection (HD-HIV) evidence of significant relation to Epstein-Barr virus (EBV), increase of mixed cellularity (MC) and lymphocyte depletion (LD) subtypes and feasibility of combined treatment with chemotherapy (CT) and zidovudine (AZT) (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A22 1994. Unique Identifier : AIDSLINE ICDB/94600019
Errante D; Tirelli U; Serraino D; Boiocchi M; Carbone A; Italian Cooperative Study Group on AIDS and Tumors (GICAT),; C.R.O. Aviano, Italy
Since November 1986, 114 cases (103 m, 11 f) of HD-HIV have been collected by the GICAT. The median age was 29 years (19-57), 80% were IVDU in accordance to the overall epidemiology of HIV infection in Italy . At the diagnosis of HD, 17% of pts had AIDS, 22% ARC, 29% PGL and 34% were


Primary central nervous system lymphoma (PCNSL) in Saskatchewan (SK): A 30-year trend (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A513 1994. Unique Identifier : AIDSLINE ICDB/94600509
Williams CK; Allan Blair Memorial Clinic, Saskatchewan Cancer Foundation,; Regina, SK, S4T 7T1, Canada
The incidence of PCNSL has recently been increasing world-wide primarily among AIDS patients, but also in immune competent population (ICP). The epidemiology of PCNSL in SK, a region of Canada where AIDS s impact on community health has been negligible, was evaluated by identifying


Changing trends of primary malignant neoplasms (PMN) in children (C) 0-15 yr and young adults (YA) 16-35 yr (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A535 1994. Unique Identifier : AIDSLINE ICDB/94600531
Samuel J; Goyal V; Cook County Hosp., Chicago, IL 60612
From January 1984 to December 1991, 7949 patients (pts) with cancer were reported in the tumor registry. 822 pts (10%) were up to age 35, of which 90 (10%) were in C, females (54%). The common PMN were cervix 23%, lymphoma and leukemia (L) 18%, Kaposi s Sarcoma (KS) (10%), breast 6% and brain 6%. In C, it was L 36% fo


Immunologic correlates in patients (pts) with head and neck cancer (SCCHN) treated with interferon alpha (IFN): association between natural killer cell (NK) activity and prolonged survival (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A900 1994. Unique Identifier : AIDSLINE ICDB/94600896
Vlock D; Andersen J; Whiteside T; Herberman R; Kirkwood J; Adams G; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; 02115
71 pts with recurrent or metastatic SCCHN were entered onto a phase II noncomparative randomized trial of IFN at 2 dosage schedules (EST P-Z386): low dose IFN, 6 x 10(6) U/m2 daily x 3 every 4 wk or high dose IFN, 12 x 10(6) U/m2, 3x/wk (Proc ASCO, 10:205). While the overall response rates were low (3 CRs) disease sta


Epstein-barr virus-associated lymphoproliferative disease (EBV-LPD) in the severe combined immune deficient human/mouse model: prevention with low dose interleukin-2 suppresses production of human interleukin-6 and interleukin-10 (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A969 1994. Unique Identifier : AIDSLINE ICDB/94600965
Baiocchi R; Sullivan L; Tan J; Narula S; Caligiuri M; Dept of Medicine, Roswell Park Cancer Inst., Buffalo, NY 14263
When severe combined immune deficient (SCID) mice are reconstituted with human PBL (hu-PBL-SCID) from individuals seropositive for Epstein-Barr virus (EBV), a fatal EBV-associated lymphoproliferative disease (EBV-LPD) of human B cell origin develops in the majority of the hu-PBL-SCID mice. These EBV-LPD tumors have a


Results in adults with small noncleaved cell (SNCL) lymphoma treated with a short duration. Intensive chemotherapy protocol also used in pediatric patients (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A1252 1994. Unique Identifier : AIDSLINE ICDB/94601248
Magrath IT; Adde M; Shad A; Wittes RE; Horak ID; NCI, Bethesda, MD
We have treated 20 adult patients with SNCL (12 BL, 7 non-BL, and 1 indeterminate) with an intensive chemotherapy protocol. None of the patients were infected with HIV. The protocol consisted of two regimens, A and B. Regimen A included CTX, ADR, VCR, and high dose MTX, and regimens B: IFOS, VP16 and high dose Ara-C.


Phase III trial of chemotherapy (CT) concomitantly with didanosine (DDI) versus chemotherapy alone in patients (pts) with AIDS-non Hodgkin's lymphoma (NHL) (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A1265 1994. Unique Identifier : AIDSLINE ICDB/94601261
Ucar A; Harrington WJ; Cabral L; Hurley J; Cohen J; Lai S; Byrnes J; Sylvester Comprehensive Cancer Center, Miami, FL
This study was designed to explore the hypothesis that combined antiretroviral and antitumor chemotherapy is feasible and more effective in terms of response and survival. Eligibility criteria included: HIV seropositivity; measurable Stage II-IV intermediate or high grade lymphoma; no prior therapy; Karnofsky PS great


Hypercalcemia in intermediate grade non-Hodgkin's lymphoma (NHL) (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A1285 1994. Unique Identifier : AIDSLINE ICDB/94601281
Jendiroba DB; Seymour JF; Swan F; Cabanillas F; UT MD Anderson Cancer Center, Houston, TX 77030
The incidence, features and prognostic significance of hypercalcemia complicating NHL have not been determined. We analyzed 183 consecutive patients (pts) with untreated intermediate-grade NHL treated on protocol between 1988 and 1992. Hypercalcemia was defined as a corrected serum calcium (CCa) of greater than 10 mg/


Cost-benefit analysis of bone marrow (BM) immunophenotyping (IP) in the staging of non-Hodgkin's lymphoma (NHL) (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A1332 1994. Unique Identifier : AIDSLINE ICDB/94601328
Denes AE; Hathaway C; St. John's Mercy Medical Center, St. Louis, MO 63141
BM IP is often used in conjunction with light microscopy (LM) in the staging evaluation of patients (pts) with NHL. We conducted a retrospective review of 50 BM staging procedures to determine the sensitivity of IP in the detection of occult BM involvement in pts with NHL. IP was performed on an Epics II Profile flow


Granulocytopenic fever (GCPF) associated with CHOP chemotherapy for intermediate grade non-Hodgkin's lymphoma (IGL); implications for the use of hematopoietic growth factors (HGF) (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A1474 1994. Unique Identifier : AIDSLINE ICDB/94601468
Rigden J; Gonin R; Nichols CR; Indiana University School of Medicine, Indianapolis, IN 46202
While Phase II trials suggested a role for dose intensive treatments in IGL, randomized comparisons have suggested that CHOP represents standard treatment (Fisher, NEJM 328(14):1002-6, 1993). Despite two decades of study, clinical aspects of CHOP treatment are not completely defined. In particular, the incidence of GC


Early lymphopenia is a risk factor for chemotherapy induced febrile neutropenia: description of a prognostic index (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A1506 1994. Unique Identifier : AIDSLINE ICDB/94601499
Blay J-Y; Anglaret B; Lasset C; Freyer G; Chauvin F; Biron P; Center L. Berard (CLB), 28 rue Laennec, 69008 Lyon, France
Febrile neutropenia (FN) is a frequent life threatening complication of cytotoxic chemotherapy (CT) whose incidence depends on the doses and drugs and individual factors. Here, we have investigated risk factors (RF) for FN in a retrospective series of 112 cancer patients (pts) treated at the CLB in 1992. Pts were over


Sharing the patient experience in the classroom with the Art for Recovery program (AFR) (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A1552 1994. Unique Identifier : AIDSLINE ICDB/94601545
Perlis C; Wallace D; Rosenbaum E; UCSF/Mount Zion Medical Center, 1600 Divisidaro St., San; Francisco CA 94120
Beginning in September of 1992, a co-operative learning/healing project was initiated involving 24 7th and 8th grade students from Brandeis Hillel Day School and 12 adult AFR participants with cancer or AIDS from the medical center. Ms Perlis delivered patients art work and letters to the students each month, facilit


Phase IV clinical evaluation of recombinant human erythropoietin (r-HuEPO) in anemic cancer patients receiving chemotherapy (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A1594 1994. Unique Identifier : AIDSLINE ICDB/94601587
Bukowski R; Glaspy J; Steinberg D; Taylor CW; Vadhan-Raj S; Sarokhan B; Lonczak L; Cleveland Clinic Foundation, Cleveland, OH
In a series of controlled clinical trials, r-HuEPO increased hematocrit and decreased transfusion requirements after the first month of therapy in anemic cancer patients undergoing chemotherapy. The present open label Phase IV study, conducted mainly in community-based oncology practices, was undertaken to confirm the


Incidence of Kaposi's sarcoma (KS), non-Hodgkin's lymphoma (NHL), and other malignancies in a cohort of gay men with human immunodeficiency virus (HIV) infection (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A2 1994. Unique Identifier : AIDSLINE ICDB/94699998
Lyter D; Bryant J; Thackeray R; Zhao P; Rinaldo C; Kingsley L; Univ. of Pittsburgh, Div. of Medical Oncology, Pittsburgh, PA
Between October 1, 1984 and November 15, 1993, 1199 gay men were followed by the Pitt Men s Study, the Pittsburgh component of the MACS, a study of the natural history of HIV infection. The cohort included 769 HIV seronegative (SN) participants and 430 who were either seropositive (SP) at enrollment or who seroconvert


Pilot study-photodynamic therapy (PDT) for treatment of AIDS-associated Kaposi's sarcoma (AIDS/KS) (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A6 1994. Unique Identifier : AIDSLINE ICDB/94600003
Bernstein ZP; Wilson D; Mang TS; Dept. of Medicine and Radiation Medicine, Roswell Park Cancer; Inst.
Lesions of AIDS/KS are often painful and cosmetically disfiguring. Treatment options are often limited by the patient s poor immune status. In an attempt to offer palliative therapy which would not further compromise the patient s immune system, we initiated a pilot study of PDT in AIDS/KS. The therapy is predicated o


Clinical trial and post-marketing safety profile of Filgrastim in oncology patients (Neupogen) (Meeting abstract).
Proc Annu Meet Am Soc Clin Oncol; 13:A543 1994. Unique Identifier : AIDSLINE ICDB/94600539
McLeish S; Decoster G; Rich W; Amgen Inc., Thousand Oaks, CA 91320-1789
Filgrastim (Neupogen) is widely used in oncology patients to decrease the incidence of infection as manifested by febrile neutropenia. We have reviewed the safety profile for Filgrastim from pre-marketing studies in oncology patients. This included data from 638 patients who participated in 14 clinical studies. These


Value of lymph node biopsy in the treatment of patients with the human immunodeficiency virus.
Am J Surg. 1991 Dec;162(6):590-2; discussion 592-3. Unique Identifier : AIDSLINE MED/94270435
Wong R; Rappaport W; Gorman S; Darragh M; Hunter G; Witzke D; University of Arizona, Department of Surgery, Tucson 85724.
The indications and value of lymph node biopsy in patients infected with the human immunodeficiency virus (HIV) are not clearly defined. We reviewed 29 consecutive lymph node biopsies performed on 24 patients with the HIV over a 4-year period. Indications for biopsy included: (1) new or worsening medical symptoms with


Drug misuse.
Occas Pap R Coll Gen Pract. 1992 Dec;(58):44-9. Unique Identifier : AIDSLINE MED/94258139
Waller T
1. Assessment by history and examination should include: a history of all drugs taken during each day for the previous 7 days (including alcohol), length of drug use and route (including the sharing of needles or syringes), the possibility of pregnancy if female, previous psychiatric history and treatment of drug misu


Is the Centers for Disease Control's latest move a cop-out or political posturing? [editorial]
AORN J. 1992 Sep;56(3):419-20. Unique Identifier : AIDSLINE MED/94280166
Palmer PN
Position on HIV and nursing students defined [news]
AORN J. 1992 Sep;56(3):506. Unique Identifier : AIDSLINE MED/94280177
[Health benefits of contraception]
Duodecim. 1992;108(23-24):2083-7. Unique Identifier : AIDSLINE MED/94283191
Luukkainen T; Helsingin yliopiston laaketieteellisen kemian laitos, Helsinki,; Finland.
[Beyond system (interview by Siv Barstad)]
J Sykepleien. 1993 Oct 5;81(16):20-1. Unique Identifier : AIDSLINE MED/94250495
Meyer M
[Operated on for panic (interview by Siv Barstad)]
J Sykepleien. 1993 Oct 5;81(16):30-1. Unique Identifier : AIDSLINE MED/94250500
Blomhoff S
[Valiant effort against AIDS (news)]
J Sykepleien. 1993 Oct 5;81(16):35. Unique Identifier : AIDSLINE MED/94250503
Global programme on AIDS. A study on the effect of blood transfusion on survival among children in a Kenyan hospital.
Wkly Epidemiol Rec. 1994 Mar 11;69(10):69-71. Unique Identifier : AIDSLINE MED/94250523
Tuberculosis in the Caribbean 1983-1992.
Wkly Epidemiol Rec. 1994 Mar 11;69(10):73-4. Unique Identifier : AIDSLINE MED/94250525
[Euthanasia--even a hopeless prognosis does not justify controlled killing]
Kinderkrankenschwester. 1994 Mar;13(3):114. Unique Identifier : AIDSLINE MED/94250540
Schell W
HIV infection and the gynaecologist [editorial]
Br J Obstet Gynaecol. 1994 Mar;101(3):187-9. Unique Identifier : AIDSLINE MED/94250610
Shah PN; Smith JR; Kitchen VS; Barton SE
Working towards a European strategy for intervention to reduce vertical transmission of HIV.
Br J Obstet Gynaecol. 1994 Mar;101(3):192-6. Unique Identifier : AIDSLINE MED/94250612
Newell ML; Peckham CS; Department of Paediatric Epidemiology, Institute of Child Health,; London.
[Usefulness of the detection of antigens and antibodies for the diagnosis of the infection by the human immunodeficiency virus (editorial)]
An Med Interna. 1994 Feb;11(2):53-5. Unique Identifier : AIDSLINE MED/94250765
Rodriguez Iglesias MA; Gutierrez Fernandez J
Pharmacokinetics of zidovudine and acetaminophen in a patient on chronic acetaminophen therapy.
Ann Pharmacother. 1994 Mar;28(3):327-30. Unique Identifier : AIDSLINE MED/94250987
Burger DM; Meenhorst PL; Koks CH; Beijnen JH; Department of Pharmacy, Slotervaart Hospital, Amsterdam, The; Netherlands.
OBJECTIVE: To report a case of a potential interaction between acetaminophen and zidovudine in a patient who had used high daily doses of acetaminophen over many years. CASE SUMMARY: A 43-year-old man presented with HIV-1 infection, recurrent oral candidiasis, and chronic use of acetaminophen, codeine, and diazepam be


Otic administration of amphotericin B 0.25% in sterile water.
Ann Pharmacother. 1994 Mar;28(3):333-5. Unique Identifier : AIDSLINE MED/94250989
Kintzel PE; Trausch DE; Copfer AL; Inpatient Pharmacy, University Medical Center, University of; Arizona Health Sciences Center, Tucson 85724.
OBJECTIVE: To report otic administration of parenteral amphotericin B 0.25% in sterile water. CASE SUMMARY: A 44-year-old HIV+ man was diagnosed with otitis externa. The patient s past medical history was remarkable for positive Coccidioides immitis serology for more than five months, essential hypertension, and Barre


Ten years after acquiring an HIV-1 infection: a study in a cohort of eleven neonates infected by aliquots from a single plasma donation.
Acta Paediatr. 1994 Feb;83(2):173-8. Unique Identifier : AIDSLINE MED/94251071
van den Berg H; Gerritsen EJ; van Tol MJ; Dooren LJ; Vossen JM; Department of Paediatrics, Leiden University Hospital, The; Netherlands.
We present data from a 10-year follow-up study of 11 children who had been infected in the neonatal period by small aliquots of plasma from a single donation. Three of the children died within the first 2.5 years of life, 5 other children died between 6.2 and 11 years after infection and 3 are alive at present. The la


Unilocular toxoplasmosis simulating intracerebral tumor.
Bildgebung. 1994 Mar;61(1):44-6. Unique Identifier : AIDSLINE MED/94251092
Fellner F; Schmitt R; Helmberger T; Busing CM; Obletter N; Institut fur Strahlendiagnostik, Klinikum Ingolstadt.
Toxoplasmosis is a common infection with increased incidence in patients suffering from AIDS. In this paper we report a rare case of toxoplasmosis without evidence of AIDS: The patient had a singular tumor-like lesion in the right parietal lobe in CT and MRI. In neurosurgical intervention no tumor was found. Finally,


Trichosanthin, a ribosome inactivating and anti-HIV protein, does not alter the concentration of beta-endorphin in the mouse brain.
Biochem Mol Biol Int. 1993 Dec;31(6):1101-4. Unique Identifier : AIDSLINE MED/94251174
Ng TB; Kwong WH; Yeung HW; Department of Biochemistry, Faculty of Medicine, Chinese; University of Hong Kong.
Trichosanthin was administered intramuscularly into mature male ICR mice at a dosage of 0.2mg/25g, daily for three days. The mice were sacrificed four hours after the last injection. Their brains were dissected out and divided into three regions: A(thalamus and hypothalamus), B(cerebral cortex) and C(cerebellum and br


Isoniazid prophylaxis of tuberculosis.
Monaldi Arch Chest Dis. 1994 Feb;49(1):88. Unique Identifier : AIDSLINE MED/94251223
Nardini S; Divisione di Pneumologia, Ospedale Civile, USL, Venezia-Mestre,; Italy.
Markedly reduced mortality associated with corticosteroid therapy of Pneumocystis carinii pneumonia in children with acquired immunodeficiency syndrome [see comments]
Arch Pediatr Adolesc Med. 1994 Jun;148(6):638-41. Unique Identifier : AIDSLINE MED/94251314
Bye MR; Cairns-Bazarian AM; Ewig JM; Division of Pediatric Pulmonary Medicine, Columbia Presbyterian; Medical Center, New York, NY.
BACKGROUND: Pneumocystis carinii pneumonia is a common opportunistic infection in pediatric acquired immunodeficiency syndrome (AIDS). Mortality rates of 34% have been reported for the acute infection, with much higher mortality rates occurring in the presence of respiratory failure. Corticosteroids reduce the morbidi


The nurse and the HIV patient--what should the healthcare policy be?
Revolution. 1993 Winter;3(4):12-6, 81. Unique Identifier : AIDSLINE MED/94251446
Monteith SK
The healing relationship.
Revolution. 1993 Winter;3(4):18-9. Unique Identifier : AIDSLINE MED/94251447
Aylor R
Recent advances in the development and use of plasma concentrates.
Br J Hosp Med. 1994 Feb 2-15;51(3):119-22. Unique Identifier : AIDSLINE MED/94251506
Soutar RL; Aberdeen Royal Infirmary.
The consequences of blood donations infected with human immunodeficiency virus, the rapid advances in protein fractionation and the introduction of recombinant DNA technology have revolutionized the range of plasma products available to the clinician. This article reviews these developments and describes recent recomm


[Drug addiction and AIDS]
Bull Acad Natl Med. 1993 Nov;177(8):1353-69. Unique Identifier : AIDSLINE MED/94251630
Gentilini M; Duneton P
[Inter- and intra-cephalic variations in pathogenicity in Toxoplasma gondii. Clinical and epidemiologic consequences]
Bull Acad Natl Med. 1993 Nov;177(8):1411-9; discussion 1419-21. Unique Identifier : AIDSLINE MED/94251636
Ambroise-Thomas P; Okay T; Departement de Parasitologie-Mycologie Medicale et; Moleculaire, Faculte de Medecine, Universite Joseph Fourier,; Grenoble.
Clinical and epidemiological studies, especially the ones conducted in HIV+ patients indicate that the pathogenicity of Toxoplasma gondii varies according to the strain considered. The differences observed among strains are represented by distinct genomic DNA patterns which could be experimentally evaluated by means o


Significance of soluble interleukin-2 receptor levels for evaluation of the progression of adult T-cell leukemia.
Cancer. 1994 Jun 1;73(11):2753-8. Unique Identifier : AIDSLINE MED/94251714
Kamihira S; Atogami S; Sohda H; Momita S; Yamada Y; Tomonaga M; Blood Transfusion Service, Nagasaki University Hospital, Japan.
BACKGROUND. The authors conducted a survey of a large cohort of patients with adult T-cell leukemia (ATL) and a group of human T-cell leukemia virus type 1 (HTLV-1) carriers to elucidate whether measurements of soluble interleukin-2 receptor (sIL-2R) levels are indicative of ATL tumor burden and correlate with clinica


Ultraviolet irradiation and cytokines as regulators of HIV latency and expression.
Chem Biol Interact. 1994 Jun;91(2-3):101-9. Unique Identifier : AIDSLINE MED/94251836
Vicenzi E; Poli G; AIDS Immunopathogenesis Unit, San Raffaele Hospital, Centro San; Luigi, Milan, Italy.
The ability of the human immunodeficiency virus (HIV) to persist and replicate in human CD4+ T lymphocytes and mononuclear phagocytes is under the control of both virally encoded proteins and a variety of host-related factors. Ultraviolet (UV) light has been shown to induce transcription and expression of HIV. Both DN


Effect of human immunodeficiency virus type 1 (HIV-1) monocyte-derived macrophages infection on the manganous superoxide dismutase gene expression.
Chem Biol Interact. 1994 Jun;91(2-3):123-31. Unique Identifier : AIDSLINE MED/94251838
Raoul H; Mabondzo A; Le Naour R; Dormont D; Laboratoire de Neuropathologie experimentale et Neurovirologie,; CRSSA/DSV/DPTE, Commissariat a l'Energie Atomique, Fontenay aux; Roses, France.
Clinical and biological features indicate that a dysregulation of microbicidal activity occurs in the cells of mononuclear phagocytic lineage of HIV-1-infected patients. Thus, the regulation of MnSOD gene expression has been investigated during the 10 h following in vitro HIV macrophage infection. As previously report


Oxygen radical release by neutrophils of HIV-infected patients.
Chem Biol Interact. 1994 Jun;91(2-3):141-6. Unique Identifier : AIDSLINE MED/94251840
Jarstrand C; Akerlund B; Department for Clinical Microbiology, Huddinge University; Hospital, Sweden.
Neutrophils from asymptomatic HIV-infected patients have an increased Nitroblue tetrazolium (NBT) reduction, that is an increased production of oxygen radicals. Plasma from these patients can activate normal neutrophils to an increased NBT-reduction and the neutrophil activating factor thus seems to be mainly plasma b


Imbalance between oxidants and antioxidants in the lungs of HIV-seropositive individuals.
Chem Biol Interact. 1994 Jun;91(2-3):147-58. Unique Identifier : AIDSLINE MED/94251841
Buhl R; Pulmonary Department/ZIM, Frankfurt University Hospital, Germany.
Following the initial infection with HIV, there is evidence of immune dysfunction despite an apparent normal clinical state. In the context that the lung is a major site affected by opportunistic infection, and that some components of the immune system are activated during early HIV infection, we hypothesized that the


Increased production of reactive oxygen species in pharmacologically-immunosuppressed patients.
Chem Biol Interact. 1994 Jun;91(2-3):159-64. Unique Identifier : AIDSLINE MED/94251842
de Lorgeril M; Richard MJ; Arnaud J; Boissonnat P; Guidollet J; Dureau G; Renaud S; Favier A; Institut National pour la Sante et la Recherche Medicale U.63,; Bron, France.
HIV-infected patients and transplanted patients share similar immunosuppressed status. Recent insights gained through the field of heart transplantation may help to clarify the role of reactive oxygen species in HIV-infected patients.


Antioxidant status and lipid peroxidation in patients infected with HIV.
Chem Biol Interact. 1994 Jun;91(2-3):165-80. Unique Identifier : AIDSLINE MED/94251843
Favier A; Sappey C; Leclerc P; Faure P; Micoud M; GREPO: Groupe de Recherches sur les Pathologies Oxydatives,; Faculte de Pharmacie, Universite de Grenoble, La Tronche,; France.
Deficiency in antioxidant micronutrients have been observed in patients with AIDS. These observations concerning only some isolated nutrients demonstrate a defect in zinc, selenium, and glutathione. An increase in free radical production and lipid peroxidation has been also found in these patients, and takes a great i


Selenium deficiency in HIV infection and the acquired immunodeficiency syndrome (AIDS).
Chem Biol Interact. 1994 Jun;91(2-3):181-6. Unique Identifier : AIDSLINE MED/94251844
Dworkin BM; Section of Nutrition, New York Medical College, Valhalla 10595.
Selenium is required for activity of the enzyme glutathione peroxidase, and selenium deficiency may be associated with myopathy, cardiomyopathy and immune dysfunction including oral candidiasis, impaired phagocytic function and decreased CD4 T-cells. We assessed selenium status in 12 patients with AIDS compared to nor


Could oxidative stress initiate programmed cell death in HIV infection? A role for plant derived metabolites having synergistic antioxidant activity [published erratum appears in Chem Biol Interact 1994 Nov;93(2):173 and 1995 Feb;94(2):165]
Chem Biol Interact. 1994 Jun;91(2-3):187-97. Unique Identifier : AIDSLINE MED/94251845
Greenspan HC; Aruoma OI; Arouma O [corrected to Aruoma OI]; LGD Biomedical Group, Annandale, NJ 08801.
Evidence supports the premise that a pro-oxidant condition exists in HIV-seropositive patients, a result of an overabundance in production of reactive oxygen forms combined with a multilevel deficiency in nutritional and metabolic sources of antioxidants. Apoptosis (a programmed cell death) is recognized as a possible


Effects of glutathione precursors on human immunodeficiency virus replication.
Chem Biol Interact. 1994 Jun;91(2-3):217-24. Unique Identifier : AIDSLINE MED/94251848
Simon G; Moog C; Obert G; Laboratoire common Universite Louis Pasteur/Synthelabo,; Strasbourg, France.
Asymptomatic human immunodeficiency virus (HIV)-seropositive individuals have reduced glutathione (GSH) levels. This has led to the suggestion that elevated intracellular thiols levels may inhibit HIV replication and progression of the disease. We confirmed that N-acetyl-L-cysteine (NAC), a cysteine prodrug which main


HIV-1 reactivation after an oxidative stress mediated by different reactive oxygen species.
Chem Biol Interact. 1994 Jun;91(2-3):79-89. Unique Identifier : AIDSLINE MED/94251850
Piette J; Legrand-Poels S; Laboratory of Fundamental Virology, University of Liege,; Belgium.
An important aspect of infection by the human immunodeficiency virus (HIV-1) type 1 is its long clinical latency period, suggesting that the provirus may remain latent for extended periods of time after primary infection. Numerous factors such as cytokines, tumor promoters, co-infection by several viruses and physical


Attitudes toward childbearing and changes in sexual and contraceptive practices among HIV-infected women.
Cleve Clin J Med. 1994 Mar-Apr;61(2):132-6; quiz 161. Unique Identifier : AIDSLINE MED/94251909
Lai KK; Department of Medicine, University of Massachusetts Medical; Center, Worcester 01655.
BACKGROUND: Women now constitute 12% of persons with acquired immunodeficiency syndrome (AIDS), and three quarters of them are well within their childbearing age. OBJECTIVE: To determine if women infected with human immunodeficiency virus (HIV) change their attitudes toward childbearing and their sexual and contracept


Human bone and tissue allografts. Preparation and safety.
Clin Orthop. 1994 Jun;(303):8-17. Unique Identifier : AIDSLINE MED/94251991
Buck BE; Malinin TI; Department of Orthopaedics and Rehabilitation, University of; Miami School of Medicine, FL 33101.
Currently, modern tissue banks routinely supply requested bone and soft-tissue allografts. These allografts are safe if tissue-bank personnel adhere to the existing methodology for excluding any donors with potential for disease transmission. The authors discard rate after excision of tissues has been approximately 1


Incidence and morbidity of infection by hepatitis C virus in children with acute lymphoblastic leukaemia.
Eur J Pediatr. 1994 Apr;153(4):271-5. Unique Identifier : AIDSLINE MED/94252360
Dibenedetto SP; Ragusa R; Sciacca A; Di Cataldo A; Miraglia V; D'Amico S; Lo Nigro L; Ippolito AM; Division of Paediatric Haematology-Oncology, University of; Catania, Italy.
A group of 90 patients with acute lymphoblastic leukaemia (ALL) in first continuous complete remission (CCR), admitted in our hospital between January 1986 and September 1992, were tested for the presence of antibodies against hepatitis C virus (HCV), antibodies against hepatitis B virus and antibodies against HIV-1 d


Visceral leishmaniasis in a child with HIV-1 infection [letter]
Eur J Pediatr. 1994 Apr;153(4):301-2. Unique Identifier : AIDSLINE MED/94252370
Guarino A; Castaldo A; Di Martino L; Rubino A; Gaeta GB; Gradoni L
Identification of the U-937 membrane-associated proteinase interacting with the V3 loop of HIV-1 gp120 as cathepsin G.
FEBS Lett. 1994 May 23;345(1):81-6. Unique Identifier : AIDSLINE MED/94252410
Avril LE; Di Martino-Ferrer M; Pignede G; Seman M; Gauthier F; Laboratoire d'Enzymologie, Centre National de la Recherche; Scientifique URA 1334, University Francois Rabelais, Faculty of; Medicine, Tours, France.
We have purified a serine proteinase from the membrane of U-937 cells that was inhibited in a tight-binding manner by recombinant gp120 and by peptides mimicking the V3 loop of gp120 [(1993) FEBS Lett. 317, 167-172]. This proteinase has now been characterized, both structurally and functionally. It has a dual trypsin-


Expression of foreign genes in cultured human primary macrophages using recombinant vaccinia virus vectors.
Gene. 1994 May 16;142(2):167-74. Unique Identifier : AIDSLINE MED/94252563
Broder CC; Kennedy PE; Michaels F; Berger EA; Laboratory of Viral Diseases, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.
Recombinant vaccinia viruses (re-VVs) provide an extremely versatile method for the expression of foreign genes in a wide range of cultured cell types of different lineages and species. In the present report, we examine the utility of re-VV vectors for re-protein production in cultured human primary macrophages obtain


[Reformulation regarding dementia. Alzheimer's disease--HIV dementia (news)]
Fortschr Med. 1994 Mar 20;112(8):20-2. Unique Identifier : AIDSLINE MED/94252642
Moosmann EB
[Treatment of patients with acquired (non-HIV) immune deficiencies]
Fortschr Med. 1994 Mar 30;112(9):117-21. Unique Identifier : AIDSLINE MED/94252646
Wilhelm M; Tony HP; Medizinische Poliklinik, Universitat Wurzburg.
Infection continues to remain a major problem in immunodeficient patients. The spectrum of pathogens differs, depending on whether one is dealing with an unspecific immune defect or a specific hormonal or cellular defect. This means that a knowledge of the type of deficiency presenting is of importance for the empiric


[Soon a fully automated HIV test will be ready for marketing (news)]
Fortschr Med. 1994 Mar 30;112(9):13. Unique Identifier : AIDSLINE MED/94252649
HTLV-I messenger RNA is expressed in vivo in adult T-cell leukemia/lymphoma patients: an in situ hybridization study.
Int J Cancer. 1994 Jun 1;57(5):760-4. Unique Identifier : AIDSLINE MED/94252726
Setoyama M; Fujiyoshi T; Mizoguchi S; Katahira Y; Yashiki S; Tara M; Kanzaki T; Sonoda S; Department of Dermatology, Faculty of Medicine, Kagoshima; University, Japan.
Adult T-cell leukemia/lymphoma (ATLL) is a malignancy involving peripheral blood, lymph nodes, skin and other organs. Human T-cell leukemia virus type I (HTLV-I) is etiologically associated with ATLL but cannot be detected by conventional methods in fresh samples of peripheral blood and skin taken from ATLL. The aim o


The knowledge, attitudes and perceived support of Tanzanian nurses when caring for patients with AIDS.
Int J Nurs Stud. 1994 Feb;31(1):77-86. Unique Identifier : AIDSLINE MED/94252792
Kohi TW; Horrocks MJ; Faculty of Nursing, Muhimbili University College of Health; Sciences, Dar es Salaam, Tanzania.
In the literature on AIDS, much attention has been paid to the Western health care workers knowledge of and attitudes toward AIDS. Little is known of the knowledge and attitudes of health care workers of developing countries. This study provides a descriptive and comparative examination of Tanzanian nurses knowledge


Planning home care services for people living with AIDS.
Home Healthc Nurse. 1994 Mar-Apr;12(2):17-23. Unique Identifier : AIDSLINE MED/94252845
Ungvarski PJ; Schmidt J; Neville S
As the number of individuals infected with the human immunodeficiency virus (HIV) increases, so does the demand for healthcare services. The debilitating manifestations seen in the later stages of illness, in association with the diagnosis of acquired immune deficiency syndrome (AIDS), often require the assistance of


Nutrition interventions for the HIV positive client.
Home Healthc Nurse. 1994 Mar-Apr;12(2):35-8. Unique Identifier : AIDSLINE MED/94252848
Merrill A
Several factors contribute to malnutrition during HIV infection. These factors can be grouped into three categories: hypermetabolism, inadequate intake, and malabsorption. This article presents a brief overview of these categories and offers suggestions to help the home healthcare nurse manage nutritional interference


Home care of a malnourished AIDS client.
Home Healthc Nurse. 1994 Mar-Apr;12(2):39-42. Unique Identifier : AIDSLINE MED/94252849
Merrill A
Many HIV positive clients experience malnutrition that may decrease the quality and length of life. The case study in this article includes study questions that provide the home healthcare nurse an opportunity to plan interventions that may increase nutrient intake.


Hospice nursing and the AIDS epidemic.
Home Healthc Nurse. 1994 Mar-Apr;12(2):54-5. Unique Identifier : AIDSLINE MED/94252853
Amenta MO; Shubert V
A rapid and simple screening method for HIV-1 protease inhibitors using recombinant Escherichia coli.
J Antibiot (Tokyo). 1994 Apr;47(4):492-5. Unique Identifier : AIDSLINE MED/94252940
Kaneto R; Kojima I; Shibamoto N; Nishida H; Okamoto R; Akagawa H; Mizuno S; Central Research Laboratories, Mercian Corporation, Fujisawa,; Japan.
Immunomodulation during treatment of polymyositis with plasmapheresis and immunosuppressive drugs.
J Clin Apheresis. 1994;9(1):21-5. Unique Identifier : AIDSLINE MED/94253025
Dau PC; Department of Medicine, Evanston Hospital, IL 60201.
Immunologic studies were carried out in a patient with polymyositis (PM), who showed increasing muscle strength and decreasing serum creatine phosphokinase levels during 20 weeks of treatment with plasmapheresis in conjunction with prednisone and cyclophosphamide. After an initial rise, serum IgG declined with treatme


Tax proteins of human T-cell leukemia virus type 1 and 2 induce expression of the gene encoding erythroid-potentiating activity (tissue inhibitor of metalloproteinases-1, TIMP-1).
J Biol Chem. 1994 May 27;269(21):14946-50. Unique Identifier : AIDSLINE GENBANK/D26513
Uchijima M; Sato H; Fujii M; Seiki M; Department of Molecular Virology and Oncology, Kanazawa; University, Ishikawa, Japan.
A growth factor-like activity for erythroid cells (erythroid-potentiating activity) is produced by the T-cells infected with human T-cell leukemia virus type 2 (HTLV-2) (Gasson, J. C., Golde, D. W., Kaufman, S. E., Westbrook, C. A., Hewick, R. M., Kaufmann, R. J., Wong, G. G., Temple, P. A., Leary, A. C., Brown, E. L.


Molecular cloning and sequencing of a 58-kDa membrane- and microfilament-associated protein from ascites tumor cell microvilli with sequence similarities to retroviral Gag proteins.
J Biol Chem. 1994 May 27;269(21):15067-75. Unique Identifier : AIDSLINE GENBANK/U15425
Juang SH; Huang J; Li Y; Salas PJ; Fregien N; Carraway CA; Carraway KL; Department of Biochemistry and Molecular Biology, University of; Miami School of Medicine, Florida 33101.
The MAT-C1 subline of the 13762 rat mammary adenocarcinoma has highly stable, branched microvilli and immobile cell surface receptors. A membrane- and microfilament-associated 58-kDa protein (p58) in the MAT-C1 microvilli has been implicated in the stabilization of the microvilli and microfilament-membrane interaction


Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein.
J Biol Chem. 1994 Jun 3;269(22):15577-82. Unique Identifier : AIDSLINE MED/94253140
Zhao LJ; Mukherjee S; Narayan O; Department of Microbiology, Molecular Genetics, and Immunology,; University of Kansas Medical Center, Kansas City 66160-7424.
vpr is an accessory gene of human immunodeficiency virus I (HIV-I). Although unnecessary for viral replication in T cell lines, growing evidence suggests that it is essential for virus replication in monocytes/macrophages and for replication in vivo. We expressed HIV-I vpr in Escherichia coli and purified Vpr by affin


Evaluation of a p21e-spiked western blot (immunoblot) in confirming human T-cell lymphotropic virus type I or II infection in volunteer blood donors. The Retrovirus Epidemiology Donor Study Group.
J Clin Microbiol. 1994 Mar;32(3):603-7. Unique Identifier : AIDSLINE MED/94253317
Kleinman SH; Kaplan JE; Khabbaz RF; Calabro MA; Thomson R; Busch M; Southern California Region American Red Cross Blood Services, Los; Angeles 90006.
Current algorithms for the serologic confirmation of human T-cell lymphotropic virus type I and II (HTLV-I/II) antibody reactivity are complicated. We evaluated the performance of an HTLV-I Western blot (immunoblot) spiked with recombinant p21e protein (p21e WB) as an alternative to current confirmatory methods. These


Detection of microsporidia by indirect immunofluorescence antibody test using polyclonal and monoclonal antibodies.
J Clin Microbiol. 1994 Mar;32(3):608-12. Unique Identifier : AIDSLINE MED/94253318
Aldras AM; Orenstein JM; Kotler DP; Shadduck JA; Didier ES; Department of Microbiology, Tulane University Regional Primate; Research Center, Covington, Louisiana 70433.
During a screening for monoclonal antibodies (MAbs) to the microsporidian Encephalitozoon hellem, three murine hybridoma cell lines producing strong enzyme-linked immunosorbent assay (ELISA) reactivities were cloned twice, were designated C12, E9, and E11, and were found to secrete MAbs to the immunoglobulin M isotype


Dilution assay statistics.
J Clin Microbiol. 1994 Mar;32(3):732-9. Unique Identifier : AIDSLINE MED/94253340
Myers LE; McQuay LJ; Hollinger FB; Research Triangle Institute, Research Triangle Park, North; Carolina 27709.
A parametric method of statistical analysis for dilution assays is developed in detail from first principles of probability and statistics. The method is based on a simple product binomial model for the experiment and produces an estimate for the concentration of target entities, a confidence interval for this concent


Comparison of PCR with direct examination of bone marrow aspiration, myeloculture, and serology for diagnosis of visceral Leishmaniasis in immunocompromised patients.
J Clin Microbiol. 1994 Mar;32(3):746-9. Unique Identifier : AIDSLINE MED/94253342
Piarroux R; Gambarelli F; Dumon H; Fontes M; Dunan S; Mary C; Toga B; Quilici M; Laboratoire de Parasitologie-Mycologie, Faculte de Medecine de; la Timone, Marseille, France.
A PCR assay amplifying a repeated sequence from the Leishmania infantum genome was compared with direct examination of bone marrow aspirate, myeloculture, and serology for the diagnosis of visceral leishmaniasis in immunocompromised patients. Of 73 patients living in an area endemic for leishmaniasis and where viscera


Bias of culture techniques for diagnosing mixed Mycobacterium genavense and Mycobacterium avium infection in AIDS.
J Clin Microbiol. 1994 Mar;32(3):828-31. Unique Identifier : AIDSLINE MED/94253357
Kirschner P; Vogel U; Hein R; Bottger EC; Institut fur Medizinische Mikrobiologie, Medizinische Hochschule; Hannover, Germany.
Disseminated Mycobacterium avium infection is a common complication in late-stage AIDS. We describe a patient seropositive for human immunodeficiency virus with a disseminated infection caused by mycobacteria. Acid-fast rods were visible by microscopy in stool and bone marrow and in specimens from skin, liver, spleen,


Utility of paired blood cultures and smears in diagnosis of disseminated Mycobacterium avium complex infections in AIDS patients.
J Clin Microbiol. 1994 Mar;32(3):841-2. Unique Identifier : AIDSLINE MED/94253361
Stone BL; Cohn DL; Kane MS; Hildred MV; Wilson ML; Reves RR; Denver Disease Control Service, Denver Health and Hospital,; Colorado 80204.
For 273 patients evaluated for disseminated Mycobacterium avium complex infection, a total of 1,047 mycobacterial blood cultures (MBCs) were submitted; the M. avium complex was recovered from 140 (13%) of the specimens. Results for the paired MBCs were highly concordant: in 392 of 462 (85%) culture sets, both MBCs wer


Report of the Committee on Infectious Diseases.
J Clin Neurophysiol. 1994 Jan;11(1):128-32. Unique Identifier : AIDSLINE MED/94253377
Periodontal diseases in HIV-infected patients.
J Clin Periodontol. 1994 Apr;21(4):270-80. Unique Identifier : AIDSLINE MED/94253406
Holmstrup P; Westergaard J; Department of Periodontology, School of Dentistry, Faculty of; Health Sciences, University of Copenhagen, Denmark.
Periodontal diseases may be the first clinical sign of human immunodeficiency virus (HIV)-infection. Since the immunosuppression and subsequent susceptibility may alter the responses of the oral tissues as well as the microflora, both periodontal treatment and result of therapy may be modified. The periodontal disease


An evaluation of the treatment effectiveness of the Chicago Health Outreach Acupuncture Clinic.
J Holist Nurs. 1994 Jun;12(2):171-83. Unique Identifier : AIDSLINE MED/94253547
Johnstone H; Marcinak J; Luckett M; Scott J
Acupuncture is a treatment modality that is particularly applicable for homeless clients because of its low cost and portability as well as because of its effectiveness in treating the symptomatology of pain syndromes, substance abuse, and human immunodeficiency virus infection. A two-part descriptive study was conduc


The influence of attitudes on the response to AIDS in the United States.
J Infect Dis. 1994 Jun;169(6):1201-5. Unique Identifier : AIDSLINE MED/94253576
Rogers DE; Department of Medicine, Cornell University Medical College, New; York, New York 10021.
Associations between HLA frequencies and pathogenic features of human immunodeficiency virus type 1 infection in seroconverters from the Amsterdam cohort of homosexual men.
J Infect Dis. 1994 Jun;169(6):1244-9. Unique Identifier : AIDSLINE MED/94253581
Klein MR; Keet IP; D'Amaro J; Bende RJ; Hekman A; Mesman B; Koot M; de Waal LP; Coutinho RA; Miedema F; Department of Clinical Viro-Immunology, Central Laboratory of The; Netherlands, Red Cross Blood Transfusion Service, Amsterdam.
HLA-disease associations may be important for understanding the pathogenesis of human immunodeficiency virus type 1 (HIV-1) infection. Therefore, 106 homosexual men from the Amsterdam Cohort Study on AIDS with a known date of HIV-1 seroconversion were serologically typed for HLA. Several significant associations betwe


Analysis of potential risk factors associated with the development of pancreatitis in phase I patients with AIDS or AIDS-related complex receiving didanosine [see comments]
J Infect Dis. 1994 Jun;169(6):1250-5. Unique Identifier : AIDSLINE MED/94253582
Grasela TH; Walawander CA; Beltangady M; Knupp CA; Martin RR; Dunkle LM; Barbhaiya RH; Pittman KA; Dolin R; Valentine FT; et al; Department of Pharmacy and Social and Preventive Medicine, State; University of New York at Buffalo, School of Pharmacy 14260.
Phase I dose-escalating trials of didanosine revealed dose-limiting toxicities, including pancreatitis, and established a total daily dose of 12.5 mg/kg/day as the maximum tolerated dose. Clinical and pharmacokinetic data of 61 patients from two trials were analyzed to further evaluate the risk of pancreatitis: 1 (6.3


The role of the major histocompatibility complex in human immunodeficiency virus infection--ever more complex? [editorial]
J Infect Dis. 1994 Jun;169(6):1332-3. Unique Identifier : AIDSLINE MED/94253594
Kaslow RA; Mann DL
Alternating nevirapine and zidovudine treatment of human immunodeficiency virus type 1-infected persons does not prolong nevirapine activity.
J Infect Dis. 1994 Jun;169(6):1346-50. Unique Identifier : AIDSLINE MED/94253598
de Jong MD; Loewenthal M; Boucher CA; van der Ende I; Hall D; Schipper P; Imrie A; Weigel HM; Kauffmann RH; Koster R; et al; Department of Virology, Academic Medical Centre, University of; Amsterdam, Netherlands.
The potential use of an alternating treatment strategy with nevirapine and zidovudine in prolonging the antiretroviral effects of nevirapine was evaluated. Ten human immunodeficiency virus type 1 (HIV-1)-infected p24 antigen-positive persons who had n


False-positive rapid plasma reagin tests in human immunodeficiency virus infection and relationship to anti-cardiolipin antibody and serum immunoglobulin levels [see comments]
J Infect Dis. 1994 Jun;169(6):1356-9. Unique Identifier : AIDSLINE MED/94253600
Rusnak JM; Butzin C; McGlasson D; Blatt SP; Department of Infectious Diseases, Wilford Hall Medical Center,; Lackland Air Force Base, Texas 78236-5300.
The incidence of biologic false-positive rapid plasma reagin (RPR) tests may be increased in human immunodeficiency virus (HIV) infection; however, injecting drug use has not been excluded as the cause. Review of 3371 periodic syphilis serology results from 1077 HIV-seropositive patients in the


Glycoforms of alpha 1-acid glycoprotein in sera of human immunodeficiency virus-infected persons.
J Infect Dis. 1994 Jun;169(6):1360-3. Unique Identifier : AIDSLINE MED/94253601
Mackiewicz A; Khan MA; Gorny A; Kapcinska M; Juszczyk J; Calabrese LH; Espinosa LR; Department of Cancer Immunology, Academy of Medicine, GreatPoland; Cancer Center, Poznan.
In acute infections thus far studied, there is a relative increase in plasma protein glycoforms rich in biantennary complex type N-glycans (type I), while in some diseases with chronic inflammatory changes, there is increase in glycoforms with more branched N-glycans (type II). In sera of 109 human immunodeficiency vi


Capacity of human immunodeficiency virus type 1 to infect chimpanzee monocytes in vitro [letter; comment]
J Infect Dis. 1994 Jun;169(6):1407-9. Unique Identifier : AIDSLINE MED/94253613
Mannhalter JW; Husch B; Kupcu Z; Eibl MM
Lymphocyte subset alterations associated with increased spontaneous lymphocyte proliferation in human T lymphotropic virus (HTLV) infection: distinctive patterns for HTLV-I versus HTLV-II infection [letter]
J Infect Dis. 1994 Jun;169(6):1409-10. Unique Identifier : AIDSLINE MED/94253614
Prince HE; Golding J; York J
Role of Fc gamma receptors in cancer and infectious disease.
J Leukoc Biol. 1994 Jun;55(6):816-26. Unique Identifier : AIDSLINE MED/94253701
Wallace PK; Howell AL; Fanger MW; Department of Microbiology, Dartmouth Medical School, Lebanon,; New Hampshire 03756.
Receptors for the Fc domain of immunoglobulin G (Fc gamma R) provide an interface between specific humoral immunity and the cellular branch of the immune system through their interaction with antibody. Cross-linking Fc gamma R on myeloid cells triggers such diverse functions as clearance of immune complexes, phagocyto


Coordinate defects in human histocompatibility leukocyte antigen class II expression and antigen presentation in bare lymphocyte syndrome.
J Exp Med. 1994 Jun 1;179(6):2017-22. Unique Identifier : AIDSLINE MED/94253742
Kovats S; Drover S; Marshall WH; Freed D; Whiteley PE; Nepom GT; Blum JS; Immunology and Diabetes Programs, Virginia Mason Research Center,; Seattle, Washington 98101.
The human immunodeficiency, type II bare lymphocyte syndrome (BLS), has been attributed to a defect in the transcription of class II histocompatibility genes. Immunocompetence, as assessed by functional exogenous antigen presentation, was not restored in immortalized B cells, derived from a BLS patient, after transfec


Florida's tuberculosis epidemic. Public health response.
J Fla Med Assoc. 1994 Mar;81(3):178-82. Unique Identifier : AIDSLINE MED/94253795
Witte JJ; Bigler WJ; State Health Office, Department of Health and Rehabilitative; Services, Tallahassee.
Florida ranked fourth in the nation with 1,707 tuberculosis cases reported in 1992 for a rate of 12.7 per 100,000 population. Thirteen percent of these patients had AIDS. Recent cases in prisons, shelters, hospitals and schools have stimulated interest and media coverage. Resurgence of strains of multiple-drug resista


Cerebrovascular and neurological disorders associated with antiphospholipid antibodies in CSF and serum.
J Neurol Sci. 1994 Mar;122(1):97-101. Unique Identifier : AIDSLINE MED/94253843
Gallo P; Sivieri S; Ferrarini AM; Giometto B; Ruffatti A; Ritter E; Chizzolini C; Tavolato B; Institute of Neurology, University of Padua, School of Medicine,; Italy.
Paired serum and cerebrospinal fluid (CSF) samples from 70 patients with inflammatory and non-inflammatory neurological diseases, as well as 10 sera from patients with primary antiphospholipid syndrome (PAS), six of which presented with cerebrovascular ischemic syndromes, were studied for the presence of anticardiolip


Immunoscintigraphy of Pneumocystis carinii pneumonia in AIDS patients [see comments]
J Nucl Med. 1994 Jun;35(6):1028-34. Unique Identifier : AIDSLINE MED/94253898
Goldenberg DM; Sharkey RM; Udem S; Vagg R; Levine GM; Conte P; Swayne LC; Hansen HJ; Cunniff D; Anton J; et al; Garden State Cancer Center at Center for Molecular Medicine and; Immunology, Newark, New Jersey 07103.
The diagnosis of Pneumocystis carinii pneumonia (PCP) currently relies upon cytological demonstration of the organism in sputum or bronchoscopy specimens. The purpose of this study was to develop a radiolabeled monoclonal antibody (Mab) against Pneumocystis carinii (P. carinii) and to evaluate its use for imaging PCP.


PCP, AIDS and nuclear medicine [editorial; comment]
J Nucl Med. 1994 Jun;35(6):1034-7. Unique Identifier : AIDSLINE MED/94253899
Kramer EL
Pneumocystis carinii pneumonia presenting as focal bibasilar uptake on gallium scan during aerosolized pentamidine prophylaxis [see comments]
J Nucl Med. 1994 Jun;35(6):1038-40. Unique Identifier : AIDSLINE MED/94253900
Katial R; Honeycutt W; Oswald SG; Department of Medicine, Dwight D. Eisenhower Army Medical Center,; Fort Gordon, Georgia.
Radionuclide imaging with gallium is commonly performed in the evaluation of patients with suspected Pneumocystis carinii pneumonia (PCP) and is known to be highly sensitive for detection of PCP. We present a patient with acquired immunodeficiency who developed PCP in the bases of both lungs while on aerosolized penta


Hyperperfusion and early technetium-99m-HMPAO SPECT appearance of central nervous system toxoplasmosis.
J Nucl Med. 1994 Jun;35(6):1041-3. Unique Identifier : AIDSLINE MED/94253901
Catafau AM; Sola M; Lomena FJ; Guelar A; Miro JM; Setoain J; Department of Nuclear Medicine, Hospital Clinic i Provincial,; University of Barcelona, Spain.
Three correlative 99mTc-HMPAO brain SPECT studies were performed on an AIDS patient from the early stage of a CNS toxoplasma lesion to its resolution after specific therapy. A hyperactive area in the right parieto-occipital lobe appeared in the first SPECT study, matching the heterogeneous T2-weighted image with Gd-DT


Occupationally acquired tuberculosis: what's known.
J Occup Med. 1994 Mar;36(3):320-5. Unique Identifier : AIDSLINE MED/94253937
Bowden KM; McDiarmid MA; National Naval Medical Center, Bethesda, Maryland.
Tuberculosis (TB) morbidity and mortality have increased substantially since the mid-1980s in areas with a high prevalence of medically underserved populations, human immunodeficiency virus, foreign-born persons, residents of long-term care facilities and crowded correctional institutions, and alcoholics and intraveno


Empyema thoracis in AIDS [editorial]
J R Soc Med. 1994 Feb;87(2):65-7. Unique Identifier : AIDSLINE MED/94254071
Coker RJ
Alternative native flap conformation revealed by 2.3 A resolution structure of SIV proteinase.
J Mol Biol. 1994 May 27;239(1):97-103. Unique Identifier : AIDSLINE MED/94254094
Wilderspin AF; Sugrue RJ; Department of Crystallography, Birkbeck College, London, England.
A large conformational change is observed between HIV-1 proteinase in the ligand-free state and in complexes with transition-state inhibitors. Crystal structures of this enzyme have either the flaps open for the native or ligand-free enzyme or the flaps closed for peptidomimetic ligand-bound enzyme. We describe the st


Syringe and needle exchange to prevent HIV infection [letter; comment]
JAMA. 1994 Jun 15;271(23):1825-6; discussion 1826-7. Unique Identifier : AIDSLINE MED/94254187
Heimer R; Lopes M
[Pathogenesis of Graves' disease]
Nippon Rinsho. 1994 Apr;52(4):1110-7. Unique Identifier : AIDSLINE MED/94254232
Yokoyama N; Nagataki S; First Department of Internal Medicine, Nagasaki University School; of Medicine.
The discovery of long acting thyroid stimulator in Graves disease and autoantibodies specific for the thyroid in Hashimoto disease in 1956, were the earliest examples of autoimmune responses. Autoimmune thyroid disease has many important advantages in the investigation of autoimmune disease when compared to the other


[Research from practice--for your work]
Krankenpfl Soins Infirm. 1994 Mar;87(3):14-8, 55-8. Unique Identifier : AIDSLINE MED/94254418
Brechbuhler M
The use of a scanning proton microprobe to observe anti-HIV drugs within cells.
Life Sci. 1994;54(21):1607-12. Unique Identifier : AIDSLINE MED/94254632
Cholewa M; Legge GJ; Weigold H; Holan G; Birch CJ; Micro Analytical Research Centre (MARC), School of Physics,; University of Melbourne, Parkville, Vic., Australia.
A series of inorganic polyanions (viz. heteropolytungstates) has been shown to have antiviral activity but there was no evidence to indicate that the drugs reached their site of antiviral (HIV) activity intact. We have shown that with a scanning proton microprobe it is possible to analyse the metal content of individu


[Ecology of Cryptococcus neoformans in central Africa]
Med Trop (Mars). 1994;54(1):53-5. Unique Identifier : AIDSLINE MED/94254704
Swinne D; Taelman H; Batungwanayo J; Bigirankana A; Bogaerts J; Laboratoire de Mycologie, Institut de Medecine Tropicale; d'Anvers, Belgique.
Cryptococcosis associated with AIDS is mainly due to Cryptococcus neoformans var. neoformans which is found in saprophytic form in pigeon droppings. This variety has been isolated in Central Africa, particularly in Zaire , Burundi and


[Tuberculosis at the time of AIDS in sub-Saharan Africa. Experience in a central African country: Burundi]
Med Trop (Mars). 1994;54(1):67-74. Unique Identifier : AIDSLINE MED/94254708
Aubry P; Kamanfu G; Mlika-Cabanne N; Nikoyagize E; Fagard C; Niyongabo T; Larouze B; Service de Medecine, Centre Hospitalier Universitaire de; Kamenge, Faculte de Medecine de Bujumbura, Burundi.
Mucosal origin of AIDS.
Med Hypotheses. 1994 Jan;42(1):43-4. Unique Identifier : AIDSLINE MED/94254744
Bourinbaiar AS; Department of Pediatrics, NYU Medical Center, NY 10016.
The natural history of AIDS implies sexual and breast-milk transmission of HIV across the mucosal lining of digestive and reproductive organs. Intraepithelial mucosal lymphocytes specialized in handling foods, air-borne, and microbial pathogens crossing the mucosal barrier represent up to 90% of immunocompetent cells


[Primary and secondary prevention of Pneumocystis carinii pneumonia with pentamidine aerosol. Effectiveness, side effects and incidence of extrapulmonary Pneumocystis carinii manifestations]
Med Klin. 1994 Mar 15;89(3):132-5. Unique Identifier : AIDSLINE MED/94254759
Stoehr A; Plettenberg A; Albrecht H; Stellbrink HJ; Meigel W; Begemann F; Allgemeines Krankenhaus St. Georg, Interdisziplinare; HIV-Ambulanz Hamburg.
BACKGROUND: We report on a retrospective study in 544 HIV-positive patients, (42 women, 502 men, mean age 35 years) showing CD4 lymphocyte counts below 200 c/mcl or after their cure of Pneumocystis carinii pneumonia, who received 300 mg pentamidine aerosol as prophylaxis against Pneumocystis carinii pneumonia every fo


Presence of negative and positive cis-acting RNA splicing elements within and flanking the first tat coding exon of human immunodeficiency virus type 1.
Mol Cell Biol. 1994 Jun;14(6):3960-70. Unique Identifier : AIDSLINE MED/94254853
Amendt BA; Hesslein D; Chang LJ; Stoltzfus CM; Department of Microbiology, University of Iowa, Iowa City 52242.
The human immunodeficiency virus type 1 (HIV-1) RNA follows a complex splicing pathway in which a single primary transcript either remains unspliced or is alternatively spliced to more than 30 different singly and multiply spliced mRNAs. We have used an in vitro splicing assay to identify cis elements within the viral


Constitutive NF-kappa B activity in neurons.
Mol Cell Biol. 1994 Jun;14(6):3981-92. Unique Identifier : AIDSLINE MED/94254855
Kaltschmidt C; Kaltschmidt B; Neumann H; Wekerle H; Baeuerle PA; Institute of Biochemistry, Albert-Ludwigs-Universitat, Freiburg,; Germany.
NF-kappa B is inducible transcription factor present in many cell types in a latent cytoplasmic form. So far, only immune cells including mature B cells, thymocytes, and adherent macrophages have been reported to contain constitutively active forms of NF-kappa B in the nucleus. A recent study showed that the human imm


Jacalin, a lectin with anti-HIV-1 properties, and HIV-1 gp120 envelope protein interact with distinct regions of the CD4 molecule.
Mol Immunol. 1994 Jun;31(8):569-75. Unique Identifier : AIDSLINE MED/94254890
Corbeau P; Haran M; Binz H; Devaux C; CRBM-UPR 9008 du CNRS, Institut de Biologie-Faculte de; Medecine, Montpellier, France.
Jacalin is a multimeric plant lectin able to interact with the lymphocyte cell-surface molecule CD4, a known receptor for the human immunodeficiency virus type 1 (HIV-1). Moreover, jacalin is able to block HIV-1 infection of CD4+ lymphoblastoid cells. Here we studied whether jacalin prevents HIV-1 gp120-CD4 interactio


Movement disorders with cerebral toxoplasmosis and AIDS [letter; comment]
Mov Disord. 1994 Mar;9(2):244-5. Unique Identifier : AIDSLINE MED/94254924
Linazasoro G
[Medical secrecy does not count in AIDS patients (news)]
Ned Tijdschr Geneeskd. 1994 Apr 30;138(18):929. Unique Identifier : AIDSLINE MED/94255034
Meijer van Putten JB
[Bell's palsy in HIV infection]
Minerva Med. 1994 Mar;85(3):117-9. Unique Identifier : AIDSLINE MED/94255098
Mastroianni A; Coronado O; Manfredi R; Chiodo F; Istituto Malattie Infettive, Universita degli Studi di Bologna.
Neurological complications represent one of the most important causes of morbidity and mortality in patients with HIV infection or AIDS. The peripheral nervous system is frequently involved in different stages of HIV disease, and the etiopathogenetic mechanisms are various. Idiopathic peripheral facial nerve palsy (Be


Intravitreal use of foscarnet: retinotoxicity of repeated injections in the rabbit eye.
Ophthalmic Res. 1994;26(2):110-5. Unique Identifier : AIDSLINE MED/94255196
Turrini B; Tognon MS; De Caro G; Secchi AG; Institute of Ophthalmology, University of Padua, School of; Medicine, Italy.
Cytomegalovirus retinitis is the most frequent ocular opportunistic infection in AIDS patients. In selected cases intravitreal injections of foscarnet may be the sole therapeutic possibility. The retinal toxicity of the drug, however, has not yet been thoroughly investigated. Our present study in the rabbit eye concer


Identification of the primary site of the human immunodeficiency virus type 1 RNA dimerization in vitro.
Proc Natl Acad Sci U S A. 1994 May 24;91(11):4945-9. Unique Identifier : AIDSLINE MED/94255445
Skripkin E; Paillart JC; Marquet R; Ehresmann B; Ehresmann C; Unite Propre de Recherche 9002 du Centre National de la; Recherche Scientifique, Institut de Biologie Moleculaire et; Cellulaire, Strasbourg, France.
The diploid genome of all retroviruses is made of two homologous copies of RNA intimately associated near their 5 end, in a region called the dimer linkage structure. Dimerization of genomic RNA is thought to be important for crucial functions of the retroviral life cycle (reverse transcription, translation, encapsid


Potent inhibition of human immunodeficiency virus type 1 replication by an intracellular anti-Rev single-chain antibody.
Proc Natl Acad Sci U S A. 1994 May 24;91(11):5075-9. Unique Identifier : AIDSLINE MED/94255473
Duan L; Bagasra O; Laughlin MA; Oakes JW; Pomerantz RJ; Dorrance H. Hamilton Laboratories, Department of Medicine,; Jefferson Medical College, Thomas Jefferson University,; Philadelphia, PA 19107.
Human immunodeficiency virus type 1 (HIV-1) has a complex life cycle, which has made it a difficult target for conventional therapeutic modalities. A single-chain antibody moiety, directed against the HIV-1 regulatory protein Rev, which rescues unspliced viral RNA from the nucleus of infected cells, has now been devel


Neurovirulent strains of Alphavirus induce apoptosis in bcl-2-expressing cells: role of a single amino acid change in the E2 glycoprotein.
Proc Natl Acad Sci U S A. 1994 May 24;91(11):5202-6. Unique Identifier : AIDSLINE MED/94255499
Ubol S; Tucker PC; Griffin DE; Hardwick JM; Department of Neurology, Johns Hopkins University School of; Medicine, Baltimore, MD 21287.
The isolation and sequence comparison of avirulent and neurovirulent strains of polio virus, alpha virus, herpes virus, immunodeficiency virus, and other viruses have identified genetic changes that are required to cause disease in the nervous system. The molecular mechanisms by which these genetic changes result in n


[Antimalarial 10 H-indolo(3,2-b)quinolin-11-yl-amines. 1. Phenol-Mannich-bases of the amodiaquine and cycloquine type.
Pharmazie. 1994 Apr;49(4):231-5. Unique Identifier : AIDSLINE MED/94255521
Gorlitzer K; Stockmann R; Walter RD; Institut fur Pharmazeutische Chemie, Technischen Universitat; Braunschweig.
The 11-chloro-quinoline derivatives 3 react with 4-aminophenol and the mono- and bis-phenol-Mannich-bases 6 to yield the 10H-indolo[3,2-b]quinoline-11-yl-amines 4 and 7. The amodiaquine analogue 7a as the best of all compounds shows a comparable activity with choroquine and inhibits a multiresistant Plasmodium falcipa


[Schizophrenia as a metaphor (editorial)]
Psychiatr Prax. 1994 Mar;21(2):47-9. Unique Identifier : AIDSLINE MED/94255557
Finzen A
Association of demographic characteristics, knowledge, and worry about HIV infection with occupational and nonoccupational behaviors of medical students.
Psychol Rep. 1994 Apr;74(2):587-93. Unique Identifier : AIDSLINE MED/94255598
Toennies LM; Zagumny MJ; Sorokin G; Tesch B; Medical College of Wisconsin.
The authors surveyed a sample of 132 medical students to assess their behaviors related to the risk of HIV infection. Scale measures were computed for survey questions relating to both occupational and nonoccupational behavior and also for questions relating to knowledge of any worry about HIV infection. Regression an


Clinically significant cognitive dysfunction in medically asymptomatic human immunodeficiency virus-infected (HIV+) individuals? [editorial; comment]
Psychosom Med. 1994 Jan-Feb;56(1):18-9. Unique Identifier : AIDSLINE MED/94255613
Martin A
Neuropsychological impairment in human immunodeficiency virus-infection: implications for employment. HNRC Group. HIV Neurobehavioral Research Center [see comments]
Psychosom Med. 1994 Jan-Feb;56(1):8-17. Unique Identifier : AIDSLINE MED/94255622
Heaton RK; Velin RA; McCutchan JA; Gulevich SJ; Atkinson JH; Wallace MR; Godfrey HP; Kirson DA; Grant I; University of California, San Diego, School of Medicine.
Individuals infected with the human immunodeficiency virus-Type 1 (HIV-1), are at increased risk for neurobehavioral impairment, particularly in later stages of the disease. Even patients in the medically asymptomatic or minimally symptomatic stages of infection may show mild deficits on comprehensive neuropsychologic


[Knowledge about HIV infection in a group of professional nursing students]
Riv Inferm. 1994 Jan-Mar;13(1):16-21. Unique Identifier : AIDSLINE MED/94255667
Villa A; De Gobbis M; Capuzzi M; Esposito A; Zanotto G; Confalonieri F
A confidential questionnaire was given to 241 students of the nursing school of a Milano Hospital to record the knowledge on HIV infection and their experience with HIV patients during their training in wards different from Infectious Departments. The results evidence a good level of knowledge, comparable to the itali


Zidovudine reduces HIV transmission from mother to infant [news]
RN. 1994 May;57(5):81. Unique Identifier : AIDSLINE MED/94255696
[HIV and blood donors: past, present and future]
Sangre (Barc). 1994 Feb;39(1):15-21. Unique Identifier : AIDSLINE MED/94255827
Leon de Gonzalez G; Hernandez T; Arias F; Celis S; Acosta V; Semprun O; Lugo de Moron M; Banco Municipal de Sangre del D.F. Servicio de; Inmunohematologia, San Jose Caracas, Venezuela.
PURPOSE: To evaluate the changes in the spectrum of HIV-positive blood donors along seven years. PATIENTS AND METHODS: The municipal Blood Bank of Caracas Federal District examined 193,796 blood donors between 1986 and 1992. Anti-HIV antibodies were determined by the following methods: Ortho HIV-Elisa Test System (59.


[Bone marrow granulomas]
Sangre (Barc). 1994 Feb;39(1):35-8. Unique Identifier : AIDSLINE MED/94255831
Vijnovich Baron IA; Barazzutti L; Tartas N; Korin J; Sanchez Avalos JC; Departamento de Patologiay Citologia, Sanatorio Guemes, Buenos; Aires, Argentina.
PURPOSE: To evaluate bone marrow granulomatous lesions in order to establish their etiology. MATERIAL AND METHODS: 2,250 bone marrow biopsies were studied during the period of March 1983-March 1991. Granulomas and/or granulomatous lesions were found in 24 of them (1.06%). A correlation between histological characteris


Infections in the immunocompromised patient.
Surg Clin North Am. 1994 Jun;74(3):609-20. Unique Identifier : AIDSLINE MED/94255849
Howard RJ; Department of Surgery, University of Florida College of Medicine,; Gainesville.
Specific microorganisms have certain types of host defenses directed at them. Inhibition of different host defenses, therefore, leads to an increased risk of the host for infection with different organisms. This article discusses the types of infections present in immunocompromised patients as well as a general approa


[Therapy of HIV infection with nucleoside analogs]
Z Gastroenterol. 1993 Nov;31 Suppl 5:60-6. Unique Identifier : AIDSLINE MED/94256156
Jablonowski H; Mauss S; Armbrecht C; Manegold C; Szelenyi H; Hengels KJ; Abteilung fur Gastroenterologie, Medizinische Klinik und; Poliklinik, Heinrich-Heine-Universitat, Dusseldorf.
[Brazil: street children in the risk zone for HIV and AIDS]
Vardfacket. 1993 Aug 26;17(13):24-5. Unique Identifier : AIDSLINE MED/94256173
Ommundsen C
Alcohol and drug use and sexual behaviors placing runaways at risk for HIV infection.
Addict Behav. 1994 Jan-Feb;19(1):95-103. Unique Identifier : AIDSLINE MED/94256250
Koopman C; Rosario M; Rotheram-Borus MJ; Department of Psychiatry & Behavioral Sciences, Stanford; University School of Medicine, CA 94305-5544.
Lifetime and current alcohol and drug use and sexual risk acts were examined among 154 male and 148 female runaways, aged 11-19, predominantly Black and Hispanic, residing at four residential shelters in the New York City area. Most runaways reported alcohol (71%) and drug use (46%), with about a quarter (27%) using e


Idiopathic, herpetic, and HIV-associated facial nerve palsies: abnormal MR enhancement patterns.
AJNR Am J Neuroradiol. 1994 Mar;15(3):479-85. Unique Identifier : AIDSLINE MED/94256300
Sartoretti-Schefer S; Wichmann W; Valavanis A; Department of Neuroradiology, University Hospital of Zurich,; Switzerland.
PURPOSE: To determine specific criteria that can be used to define normal versus abnormal MR contrast enhancement of the facial nerve. METHODS: Twenty-three patients with acute unilateral inflammatory peripheral facial nerve palsy were examined on a 1.5-T MR using multiplanar T1-weighted spin-echo sequences before and


Intestinal permeability in patients infected with the human immunodeficiency virus.
Am J Gastroenterol. 1994 Jun;89(6):878-82. Unique Identifier : AIDSLINE MED/94256460
Tepper RE; Simon D; Brandt LJ; Nutovits R; Lee MJ; Division of Gastroenterology, Bronx Municipal Hospital Center,; New York.
OBJECTIVE: The etiology of acquired immunodeficiency syndrome (AIDS) enteropathy is unknown. This condition has been associated with malabsorption and villous atrophy. Other disorders with similar findings, including celiac disease, are characterized by altered intestinal permeability. Our objective was to confirm (or


Combined daily therapy with intravenous ganciclovir and foscarnet for patients with recurrent cytomegalovirus retinitis.
Am J Ophthalmol. 1994 Jun 15;117(6):776-82. Unique Identifier : AIDSLINE MED/94256533
Weinberg DV; Murphy R; Naughton K; Department of Ophthalmology, Northwestern University Medical; School, Chicago, Illinois.
We treated seven patients (nine eyes) who had cytomegalovirus retinitis with daily intravenous ganciclovir plus foscarnet. All patients had demonstrated multiple progressions of retinitis on single-drug therapy, and some were intolerant to induction doses of one or both medications


Risk factors for development of rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis [letter; comment]
Am J Ophthalmol. 1994 Jun 15;117(6):820-1. Unique Identifier : AIDSLINE MED/94256550
Geier SA; Klauss V; Goebel FD
Flow cytometric analysis of lymphocyte subsets of mice maintained on an ethanol-containing liquid diet.
Alcohol Clin Exp Res. 1994 Feb;18(1):12-20. Unique Identifier : AIDSLINE MED/94256579
Hsiung L; Wang J; Waltenbaugh C; Department of Microbiology-Immunology, Northwestern University; Medical School, Chicago, IL 60611.
Alcoholic patients often have impaired immune function, yet little is known about the precise mechanism(s) of this impairment. We have previously shown that ethanol consumption by mice alters copolymer-specific humoral and cellular immune responses. In this study, we asked whether alcohol consumption by mice would phe


Effect of postnatal ethanol exposure on expression of differentiation antigens of murine splenic lymphocytes.
Alcohol Clin Exp Res. 1994 Feb;18(1):21-8. Unique Identifier : AIDSLINE MED/94256594
Giberson PK; Blakley BR; Department of Veterinary Physiological Sciences, Western College; of Veterinary Medicine, University of Saskatchewan, Saskatoon,; Canada.
Ethanol is a recognized immunosuppressive agent in the chronic alcoholic. However, the effects of ethanol exposure on the developing immune system have not been extensively investigated. This study evaluated the effects of early postnatal ethanol exposure, via breast milk, on splenic lymphocyte differentiation antigen


Modification of lymphocyte subsets in the intestinal-associated immune system and thymus by chronic ethanol consumption.
Alcohol Clin Exp Res. 1994 Feb;18(1):8-11. Unique Identifier : AIDSLINE MED/94256603
Lopez MC; Huang DS; Borgs P; Wang Y; Watson RR; Department of Family and Community Medicine, Arizona Health; Sciences Center, Tucson 85724.
Modification of the mucosa-associated intestinal immune system of female C57BL/6 mice was studied during consumption of the Lieber-DeCarli diet supplemented with 5% v/v ethanol or laboratory chow with ethanol (20% w/v) in the drinking water. All groups received ethanol for 11 weeks. Mice fed the Lieber-DeCarli diet ha


Allergen-induced expression of cell surface markers on lymphocytes of Chi t I-sensitized patients.
Allergy. 1994 Mar;49(3):163-9. Unique Identifier : AIDSLINE MED/94256625
Liebers V; Raulf M; Baur X; Berufsgenossenschaftliches Forschungsinstitut fur Arbeitsmedizin; (BGFA), Ruhr-Universitat Bochum, Germany.
Lymphocyte cultures of persons sensitized to the hemoglobin allergen Chi t I show a highly significant response to the allergen measured in the lymphocyte stimulation assay by (3H)-thymidine uptake. In this study, we investigated by flow cytometry the expression of different cell surface markers on lymphocytes after i


The HIV-positive physician and disability insurance.
Ann Emerg Med. 1994 Jun;23(6):1355-62. Unique Identifier : AIDSLINE MED/94256695
Lavely R; Department of Public Health, Yale School of Medicine, New Haven,; Connecticut.
Occupational exposure to HIV is becoming a daily hazard in many emergency departments. Emergency physicians who are protected by disability insurance policies are likely to believe that if they are unable to continue working because of HIV-positive status, their disability policies will provide them with a source of i


Induction of apoptosis in a T lymphoblastoid cell line infected with feline immunodeficiency virus.
Arch Virol. 1994;135(1-2):153-8. Unique Identifier : AIDSLINE MED/94256834
Ohno K; Okamoto Y; Miyazawa T; Mikami T; Watari T; Goitsuka R; Tsujimoto H; Hasegawa A; Department of Veterinary Internal Medicine, Faculty of; Agriculture, University of Tokyo, Japan.
The mechanism of cell death induced by feline immunodeficiency virus (FIV) infection was investigated in an interleukin 2( IL-2 )-dependent T-lymphoblastoid cell line (MYA-1). DNA extracted from FIV-infected MYA-1 cells showed a ladder of nucleosomal DNA, indicating that


Expression of env gene of bovine leukemia virus in rodent cells.
Arch Virol. 1994;135(1-2):201-7. Unique Identifier : AIDSLINE MED/94256841
Zajac V; Slavikova K; Babusikova O; Department of Experimental Pathology, Slovak Academy of Sciences,; Bratislava.
The BamHI-BamHI fragment of the env gene of bovine leukemia virus (BLV) cloned in pMMEx expression vector was transfected into Chinese hamster cells. Monoclonal antibodies (MAbs) directed against both conformational and sequential epitopes of gp51 of BLV recognized viral polypeptides expressed in hamster cells in West


Salmonella typhimurium activates human immunodeficiency virus type 1 in chronically infected promonocytic cells by inducing tumor necrosis factor-alpha production.
Biochem Biophys Res Commun. 1994 May 30;201(1):16-23. Unique Identifier : AIDSLINE MED/94256973
Andreana A; Gollapudi S; Kim CH; Gupta S; Division of Basic and Clinical Immunology, University of; California, Irvine 92717.
The effect of phagocytosis of Salmonella typhimurium on human immunodeficiency virus type 1 (HIV-1) production was investigated using a chronically infected promonocytic cell line (U1) that contains HIV-1 provirus but produces little or no HIV-1. The phagocytosis of virulent S. typhimurium by U1 cells resulted in an i


Competitive inhibition of HIV-1 protease by warfarin derivatives.
Biochem Biophys Res Commun. 1994 May 30;201(1):290-4. Unique Identifier : AIDSLINE MED/94256992
Tummino PJ; Ferguson D; Hupe D; Department of Biochemistry, Parke-Davis Pharmaceutical Research,; Division of Warner-Lambert Company, Ann Arbor, Michigan 48105.
The oral anticoagulant warfarin (4-hydroxy-3-(3-oxo-1-phenylbutyl)- benzopyran-2-one) is a structurally novel low micromolar competitive inhibitor of HIV-1 protease in vitro. It was recently reported that warfarin inhibits HIV-1 infection in U-1 monocytes and viral production in ACH-2 lymphocytes (Bourinbaiar, A.S. et


Macrogolgin--a new 376 kD Golgi complex outer membrane protein as target of antibodies in patients with rheumatic diseases and HIV infections.
J Autoimmun. 1994 Feb;7(1):67-91. Unique Identifier : AIDSLINE GENBANK/X75304
Seelig HP; Schranz P; Schroter H; Wiemann C; Renz M; Institute of Immunology and Molecular Genetics, Karlsruhe,; Germany.
Antibodies against the Golgi complex (GC) were found by indirect immunofluorescence microscopy in the serum of two patients with sclerodermia and Sjogren syndrome. Serum from one patient was used to screen clones from an oligo (dT) primed HeLa cDNA expression library. Four overlapping cross hybridizing clones (G1, G12


History of the Euro Skin Bank: the innovation of preservation technologies.
Burns. 1994;20 Suppl 1:S43-7. Unique Identifier : AIDSLINE MED/94257162
Hoekstra MJ; Kreis RW; du Pont JS; Euro Skin Bank, Research Department, Beverwijk, The Netherlands.
A skin bank facility is indispensable for burn care. In Holland, a skin bank was established in October 1976 on a national basis for economical reasons. Since 1981, overcoming early rejection by innovation of existing, and development of new, preservation technologies became the main scientific objective. The immunolo


Virucidal effect of glycerol as used in donor skin preservation [see comments]
Burns. 1994;20 Suppl 1:S77-80. Unique Identifier : AIDSLINE MED/94257169
van Baare J; Buitenwerf J; Hoekstra MJ; du Pont JS; Euro Skin Bank, Research Department, Beverwijk, The Netherlands.
Glycerol has been used for a long time as a viral preservation medium in tissue samples at a 50 per cent concentration, however after a limited time span viruses could no longer be detected. This fact combined with the dehydrating action of glycerol, raised the suspicion that glycerol in a higher concentration could b


Cohort study of HIV infection among drug users in Ruili, Longchuan and Luxi of Yunnan Province, China.
Biomed Environ Sci. 1993 Dec;6(4):348-51. Unique Identifier : AIDSLINE MED/94257171
Zheng XW; Zhang JP; Tian CQ; Cheng HH; Yang XZ; Duan S; Li DQ; Institute of Epidemiology and Microbiology, Chinese Academy of; Preventive Medicine, Beijing.
In March 1992, KAP investigation and HIV blood test were carried out for 860 drug users and 82 spouses in Ruili, Luxi, Longchuan of Yunnan Province, China . The results showed that there were 285 injecting drug users (IDUs) (33.1%) among 860 drug users. Among 282 blood samples of IDU


Molecular biology of HIV: challenges for the second decade.
AIDS Res Hum Retroviruses. 1994 Feb;10(2):111-2. Unique Identifier : AIDSLINE MED/94257313
Poeschla E; Wong-Staal F; Department of Medicine, University of California, San Diego, La; Jolla 92093-0665.
Human immunodeficiency virus type 1 infection of neonatal severe combined immunodeficient mice xenografted with human cord blood cells.
AIDS Res Hum Retroviruses. 1994 Feb;10(2):131-41. Unique Identifier : AIDSLINE MED/94257317
Reinhardt B; Torbett BE; Gulizia RJ; Reinhardt PP; Spector SA; Mosier DE; Department of Pediatrics, University of California, San Diego, La; Jolla 92037-0672.
In these studies, neonatal C.B-17 severe combined immunodeficient (nSCID) mice were reconstituted with human cord blood leukocytes (hu-CBLs). The resulting hu-CBL-nSCID mice contained readily detectable human CD3+ T lymphocytes and CD20+ human B cells, and produced substantial levels of human IgM and IgG (including al


Identification of novel neutralization-inducing regions of the human T cell lymphotropic virus type I envelope glycoproteins with human HTLV-I-seropositive sera.
AIDS Res Hum Retroviruses. 1994 Feb;10(2):163-73. Unique Identifier : AIDSLINE MED/94257321
Desgranges C; Souche S; Vernant JC; Smadja D; Vahlne A; Horal P; INSERM U271, Lyon, France.
The humoral immune response in sera from 30 human T cell lymphotropic virus type I (HTLV-I)-positive individuals from Martinique in the French West Indies was studied. The subjects were subdivided into those suffering from TSP/HAM a


Human herpesvirus 6 envelope glycoproteins B and H-L complex are undetectable on the plasma membrane of infected lymphocytes.
AIDS Res Hum Retroviruses. 1994 Feb;10(2):175-9. Unique Identifier : AIDSLINE MED/94257322
Cirone M; Campadelli-Fiume G; Foa-Tomasi L; Torrisi MR; Faggioni A; Department of Experimental Medicine, University of Rome La; Sapienza, Italy.
Membrane immunofluorescence analysis of cells infected with either variant (A or B) of human herpesvirus 6 revealed a typical punctate staining, after labeling with several HHV-6-positive human sera or with two monoclonal antibodies directed to gB and gH. Immunoprecipitation studies showed a sharp difference in glycop


In vitro susceptibility of Macaca nemestrina to human herpesvirus 6: a potential animal model of coinfection with primate immunodeficiency viruses.
AIDS Res Hum Retroviruses. 1994 Feb;10(2):181-7. Unique Identifier : AIDSLINE MED/94257323
Lusso P; Secchiero P; Crowley RW; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.
Human herpesvirus 6 (HHV-6), a lymphotropic herpesvirus, has been suggested as a potential cofactor in the acquired immunodeficiency syndrome (AIDS). Previous studies indicate that HHV-6 has a restricted range of susceptible species. In this study, we tested the in vitro susceptibility to HHV-6 of Macaca nemestrina (p


Passive immunization of cynomolgus macaques with immune sera or a pool of neutralizing monoclonal antibodies failed to protect against challenge with SIVmac251.
AIDS Res Hum Retroviruses. 1994 Feb;10(2):189-94. Unique Identifier : AIDSLINE MED/94257324
Kent KA; Kitchin P; Mills KH; Page M; Taffs F; Corcoran T; Silvera P; Flanagan B; Powell C; Rose J; et al; National Institute for Biological Standards and Control, South; Mimms, Potters Bar, Herts, England.
In the first of two passive transfer experiments, three groups of four macaques were injected intraperitoneally with a normal serum pool, an immune serum pool (pool 1) collected 132-172 weeks postinfection with the 11/88 pool of SIVmac251, or with a pool of four neutralizing monoclonal antibodies (KK9, 17, 54, and 56)


Reduced virus load in rhesus macaques immunized with recombinant gp160 and challenged with simian immunodeficiency virus.
AIDS Res Hum Retroviruses. 1994 Feb;10(2):195-204. Unique Identifier : AIDSLINE MED/94257325
Ahmad S; Lohman B; Marthas M; Giavedoni L; el-Amad Z; Haigwood NL; Scandella CJ; Gardner MB; Luciw PA; Yilma T; Department of Pathology, Microbiology, and Immunology, University; of California at Davis 95616.
As a safe alternative to inactivated and live-attenuated whole-virus SIV vaccines, we have evaluated the potential of SIVmac239 gp160 expressed by recombinant vaccinia virus (vSIVgp160) and baculovirus (bSIVgp160) to protectively immunize rhesus macaques against intravenous (i.v.) infection with pathogenic SIVmac isol


Production of long-lived neutralizing antibodies to HIV-1 IIIB in mice with a vaccinia recombinant virus-infected cell vaccine expressing gp160.
AIDS Res Hum Retroviruses. 1994 Feb;10(2):205-12. Unique Identifier : AIDSLINE MED/94257326
Parry C; McLain L; Dimmock NJ; Department of Biological Sciences, University of Warwick,; Coventry, England.
A formaldehyde-fixed cell vaccine in adjuvant (syngeneic cells infected with a vaccinia virus recombinant expressing gp160: vacc-gp160) stimulated only nonneutralizing antibody when used on its own in four strains of mice, but a similar nonfixed cell vaccine stimulated neutralizing antibodies up to a titer of 1/320 in


Titration and characterization of two rhesus-derived SIVmac challenge stocks.
AIDS Res Hum Retroviruses. 1994 Feb;10(2):213-20. Unique Identifier : AIDSLINE MED/94257327
Lewis MG; Bellah S; McKinnon K; Yalley-Ogunro J; Zack PM; Elkins WR; Desrosiers RC; Eddy GA; Henry M. Jackson Foundation, Rockville, Maryland 20850.
Simian immunodeficiency virus infection of macaques is a model for human immunodeficiency virus infection of humans. In vivo-titrated stocks of SIV are essential for the utilization of this model for vaccine development. The elicitation of anti-human cell antibodies by some vaccines prepared in human cells and the rel


Feasibility of developing live attenuated HIV vaccines: conclusions and recommendations. World Health Organization Working Group.
AIDS Res Hum Retroviruses. 1994 Feb;10(2):221-2. Unique Identifier : AIDSLINE MED/94257328
Guidelines on HIV testing [news]
Nurs Stand. 1994 Apr 13-19;8(29):8. Unique Identifier : AIDSLINE MED/94257468
Adult T-cell leukaemia/lymphoma featuring a large granular lymphocyte leukaemia morphologically.
Br J Haematol. 1994 Feb;86(2):383-5. Unique Identifier : AIDSLINE MED/94257503
Sakamoto Y; Kawachi Y; Uchida T; Abe T; Mori M; Setsu K; Indo N; Department of Internal Medicine, Takamatsu Red Cross Hospital,; Kagawa, Japan.
A 70-year-old man from an endemic area of human T-cell lymphotropic virus type I (HTLV-I) developed rapid generalized lymphadenopathy and abdominal tumours. The white blood cell count was 198.3 x 10(9)/l with 93% lymphocytes, 66.3% of which expressed large granular lymphocytes (LGLs). Bone marrow and lymph nodes were


XrelA, a Xenopus maternal and zygotic homologue of the p65 subunit of NF-kappa B. Characterisation of transcriptional properties in the developing embryo and identification of a negative interference mutant.
Mech Dev. 1994 Feb;45(2):173-89. Unique Identifier : AIDSLINE MED/94257534
Richardson JC; Garcia Estrabot AM; Woodland HR; Department of Biological Sciences, University of Warwick,; Coventry, UK.
We have isolated two clones (XrelA.1 and XrelA.2) from Xenopus ovary representing differentially processed mRNAs homologous throughout their translated regions to the mammalian p65 subunit of NF-kappa B. The transcripts are ubiquitously present throughout development, but are most abundant in late blastulae and gastru


Aggressive orbital lymphoma in AIDS.
Br J Ophthalmol. 1994 Apr;78(4):319-21. Unique Identifier : AIDSLINE MED/94257606
Rahhal FM; Rosberger DF; Heinemann MH; Department of Ophthalmology, New York Hospital-Cornell University; Medical College, New York.
Oligonucleotide-poly(L-lysine)-heparin complexes: potent sequence-specific inhibitors of HIV-1 infection.
Bioconjug Chem. 1994 Jan-Feb;5(1):8-13. Unique Identifier : AIDSLINE MED/94257725
Degols G; Devaux C; Lebleu B; Institut de Genetique Moleculaire Montpellier,; CNRS-Universite de Montpellier, France.
Poly(L-lysine)-conjugated oligonucleotides complementary to the translation initiation region of the tat protein were tested for their capacity to inhibit HIV-1 replication in de novo infected cells. Sequence-specific antiviral effects were observed with these conjugates at 0.5 microM; their activity was transient, an


Acquired heart disease in children.
Curr Opin Cardiol. 1994 Jan;9(1):121-9. Unique Identifier : AIDSLINE MED/94257868
Bezold LI; Bricker JT; Baylor College of Medicine, Texas Children's Hospital, Houston.
Recent advances have been made in understanding Kawasaki disease, acute rheumatic fever and rheumatic heart disease, cardiomyopathy, and acquired immunodeficiency syndrome. Immune-mediated tissue injury in Kawasaki disease is likely caused by response to a superantigen. Persistent functional and anatomic coronary abno


Inadequate dietary intake and altered nutrition status in early HIV-1 infection.
Nutrition. 1994 Jan-Feb;10(1):16-20. Unique Identifier : AIDSLINE MED/94257925
Baum M; Cassetti L; Bonvehi P; Shor-Posner G; Lu Y; Sauberlich H; Department of Epidemiology and Public Health, University of Miami; School of Medicine, Florida 33101.
Recent studies indicate that multiple nutritional abnormalities occur relatively early in the course of human immunodeficiency virus (HIV-1) infection. Decreased plasma levels of vitamins B6, B12, A, and E and zinc have been correlated with dietary intake and associated with significant alterations in immune response


[HIV and travel. Advice concerning immunizations and pre-travel evaluation]
Can Fam Physician. 1994 Apr;40:740-5. Unique Identifier : AIDSLINE MED/94258038
Tessier D; Gervais F; Clinique sante-voyage de l'Hopital Saint-Luc.
HIV and AIDS infection has reached epidemic proportions; however, advances in treatment have made it possible for an increasing number of infected individuals to travel. These patients should be given travel advice before they leave. Mainly for political reasons, they should be advised to avoid certain countries. For


BC's AIDS road show. Evolution of a good idea [news]
Can Fam Physician. 1994 Apr;40:842-3. Unique Identifier : AIDSLINE MED/94258042
McNeil L
[Predictors of sexual behavior in a group of heterosexual university students at risk for AIDS in Montreal]
Contracept Fertil Sex. 1994 Feb;22(2):123-8. Unique Identifier : AIDSLINE MED/94258234
Levy JJ; Frigault LR; Samson JM; Dupras A; Cappon P; Departement de sexologie, Universite du Quebec a Montreal,; Canada.
In order to evaluate the predictors of risky sexual behavior and AIDS, 573 male and female college students enrolled in French speaking universities in Montreal answered a questionnaire dealing with their sexual behaviors, from which an index of risks was computed (CASH). The analyses show that the best predictors of


Risk of infection from blood and blood products in the context of the AIDS scandal in Germany.
Int J Clin Pharmacol Ther. 1994 Jan;32(1):2-6. Unique Identifier : AIDSLINE MED/94258370
Kretschmer V; Abteilung fur Transfusionsmedizin und Gerinnungsphysiologie,; Universitats-Klinikums in Marburg, Germany.
The association of physical and sexual abuse with HIV risk behaviors in adolescence and young adulthood: implications for public health.
Child Abuse Negl. 1994 Mar;18(3):233-45. Unique Identifier : AIDSLINE MED/94258556
Cunningham RM; Stiffman AR; Dore P; Earls F; George Warren Brown School of Social Work, Washington University,; St. Louis, MO 63130.
This paper explores the relationship between changes in HIV risk behaviors and physical and sexual abuse. A stratified random sampling procedure selected 602 youths from a sample of 2,787 patients seen consecutively at public health clinics in 10 cities. Face-to-face structured interviews conducted since 1984-85 provi


Keep facts from patients at your peril, Ontario court warns doctors.
Can Med Assoc J. 1994 Jun 1;150(11):1863-5. Unique Identifier : AIDSLINE MED/94258619
Capen K
Epstein-Barr virus in patients with polymorphic reticulosis (lethal midline granuloma) from China and Japan.
Cancer. 1994 Jun 15;73(12):3041-6. Unique Identifier : AIDSLINE MED/94258673
Mishima K; Horiuchi K; Kojya S; Takahashi H; Ohsawa M; Aozasa K; Department of Pathology, Nara Medical College, Kashihara, Japan.
BACKGROUND. Polymorphic reticulosis is one of several diseases constituting lethal midline granuloma (LMG). Previous immunohistochemical studies suggested a T-cell nature of proliferating cells; the term nasal T-cell lymphoma (NTL-LMG) has since been used widely. The authors previous study in Asian countries showed t


Posttransplant T-cell lymphoma. Report of three cases and a review of the literature.
Cancer. 1994 Jun 15;73(12):3064-72. Unique Identifier : AIDSLINE MED/94258676
van Gorp J; Doornewaard H; Verdonck LF; Klopping C; Vos PF; van den Tweel JG; Department of Pathology, University Hospital, Utrecht, The; Netherlands.
BACKGROUND. Although 14% of the malignant lymphomas after organ transplantation are reported to be T-cell lymphomas, only a few cases are described in the literature. METHODS. The authors presented three new cases. They summarized the clinical data and analyzed histologic and immunochemical findings. The presence of E


Synthetic peptides of human CD4 enhance binding of immunoglobulins to monocyte/macrophage cells. II. Mechanisms of enhancement.
Cell Immunol. 1994 Jun;156(1):146-54. Unique Identifier : AIDSLINE MED/94258711
Mehta RL; Lenert P; Zanetti M; Department of Medicine, University of California, San Diego, La; Jolla 92093.
We have previously shown that a synthetic peptide corresponding to amino acid residues 21-49 of the first extracellular domain of human CD4 binds immunoglobulins (Ig) and antibody: antigen (Ab:Ag) complexes, and greatly enhances the uptake of aggregated Ig by monocyte/macrophage U937 cells. In this report, we investig


Leukocytes migrate through three-dimensional gels of midcycle cervical mucus.
Cell Immunol. 1994 Jun;156(1):77-94. Unique Identifier : AIDSLINE MED/94258727
Parkhurst MR; Saltzman WM; Department of Chemical Engineering, Johns Hopkins University,; Baltimore, Maryland 21218.
The migration of leukocytes through mucus must be an essential factor in the mucosal immune response, particularly during mucosal invasion by pathogens. We used two methods to evaluate the ability of neutrophils to migrate through human midcycle cervical mucus: (i) direct visualization of cell migration within freshly


Induction of graft versus host disease in SCID mice by MRL/lpr cell transfer.
Clin Immunol Immunopathol. 1994 Jun;71(3):265-72. Unique Identifier : AIDSLINE MED/94258819
Fraziano M; Montesano C; Sammarco I; di Cesare S; Caroleo MC; Mattei M; Cannata S; Poccia F; Bellavia A; Salerno A; et al; Department of Biology, University of Rome, Tor Vergata, Italy.
We have investigated the graft versus host (GvH) disease induced in immunodeficient SCID (H-2d) mice by intravenous (iv) or intraperitoneal (ip) transfer of either spleen or lymph node cells from autoimmune (MRL/lpr and MRL/++ mice, H-2k) and normal (CBA, H-2k) mice. Rapid and lethal GvH disease was observed when cell


Structural and functional similarities between synthetic HIV gp41 peptides and defensins.
Clin Immunol Immunopathol. 1994 Jun;71(3):315-24. Unique Identifier : AIDSLINE MED/94258826
Monell CR; Strand M; Department of Pharmacology and Molecular Sciences, Johns Hopkins; University School of Medicine, Baltimore, Maryland 21205.
Synthetic peptides derived from the putative immunosuppressive region of HIV-1 gp41 were examined to identify the amino acids required for suppressive activity. The active sequence was similar to the pseudosubstrate regulatory peptide of protein kinase C and to a sequence from the cyclic immune peptides known as defen


Fulminant amebic colitis. A morphologic study of four cases.
Dis Colon Rectum. 1994 Jun;37(6):535-9. Unique Identifier : AIDSLINE MED/94258928
Chun D; Chandrasoma P; Kiyabu M; Department of Pathology, Los Angeles County-University of; Southern California Medical Center, University of Southern; California School of Medicine, 90033.
PURPOSE: The morphologic features of fulminant amebic colitis are poorly documented. In this report, we describe the clinical and pathologic findings in four of these cases. METHODS: The surgical pathology reports and accompanying histologic slides were examined from four patients who underwent surgical resections for


[Biotechnology vaccines--development of new disease prevention. Research progress of Biocine in Siena--HIV, herpes, Helicobacter]
Fortschr Med. 1994 Apr 20;112(11):53-4. Unique Identifier : AIDSLINE MED/94259369
Keil TU
[AIDS: management still inadequate. Ambulatory care--AIDS counseling]
Fortschr Med. 1994 Apr 30;112(12):32. Unique Identifier : AIDSLINE MED/94259374
Karcher HL
An assessment of Arab American knowledge, attitudes, and beliefs about AIDS.
Image J Nurs Sch. 1994 Spring;26(1):13-7. Unique Identifier : AIDSLINE MED/94259455
Kulwicki A; Cass PS; Oakland University School of Nursing, Rochester, MI 48309-4401.
An important component of an effective AIDS prevention program is the dissemination of relevant information concerning AIDS risk behaviors. The purpose of this study was to identify the knowledge, attitudes, and beliefs of 411 randomly selected Arab Americans. The results indicate a low level of self-assessed knowledg


Contributing factors to fear of HIV contagion in registered nurses.
Image J Nurs Sch. 1994 Spring;26(1):65-9. Unique Identifier : AIDSLINE MED/94259463
Meisenhelder JB; Center for Nursing Research, New England Deaconess Hospital,; Boston, MA 02215.
This study tested the relationships of homophobia, fear of the unknown, fear of death, and fear of punishment as predictors of fear of HIV contagion. Knowledge of transmission and emotional involvement with a person at risk for HIV were hypothesized as decreasing fear among 114 randomly-selected RNs. Results supported


Transcription of individual genes in eukaryotic cells occurs randomly and infrequently.
Immunol Cell Biol. 1994 Apr;72(2):177-85. Unique Identifier : AIDSLINE MED/94259476
Ross IL; Browne CM; Hume DA; Centre for Molecular Biology and Biotechnology, University of; Queensland, Brisbane, Australia.
Experimental evidence is presented indicating that the expression of a lacZ reporter gene driven by the HIV-1 long terminal repeat in a series of stably transfected, cloned macrophage cell lines occurs in a very small proportion of cells. The proportion of cells expressing lacZ, rather than the level of expression in


The incidence of the acquired immunodeficiency syndrome (AIDS) has peaked [editorial]
J Am Osteopath Assoc. 1994 Mar;94(3):215. Unique Identifier : AIDSLINE MED/94259623
Lethal midline granuloma in Okinawa with special emphasis on polymorphic reticulosis.
Jpn J Cancer Res. 1994 Apr;85(4):384-8. Unique Identifier : AIDSLINE MED/94259652
Kojya S; Itokazu T; Maeshiro N; Esu H; Noda Y; Mishima K; Ohsawa M; Aozasa K; Department of Otorhinolaryngology, University of the Ryukyus; Faculty of Medicine, Okinawa.
Lethal midline granuloma (LMG) is a clinical term used to describe a condition which may be manifested histologically as Wegener s granulomatosis (WG), polymorphic reticulosis (PR), and malignant lymphoma (ML). WG is an inflammatory disease, and PR and ML are considered to represent a neoplastic proliferation of lymph


African American college students' health behaviors and perceptions of related health issues.
J Am Coll Health. 1994 Mar;42(5):206-10. Unique Identifier : AIDSLINE MED/94259976
Ford DS; Goode CR; Department of Physical Education and Recreation, Howard; University, Washington, DC.
The authors identify specific health-related behaviors of African American college students and compare them with the students perceptions of corresponding health issues. Among students surveyed, the rate of cigarette smoking (4%) was very low compared with smoking rates found in a national survey (14%); but alcohol


Challenging heterosexism in college health service delivery.
J Am Coll Health. 1994 Mar;42(5):211-6. Unique Identifier : AIDSLINE MED/94259977
McKee MB; Hayes SF; Axiotis IR; Stonewall Recovery Services in Seattle, Washington.
The empowerment and affirmation of lesbian, bisexual, and gay students is long overdue. This article explores how human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS), substance abuse, violence and hate-related crimes, suicide, and heterosexism all adversely affect the physical and emotional


A model for HIV risk reduction and prevention among African American college students.
J Am Coll Health. 1994 Mar;42(5):220-3. Unique Identifier : AIDSLINE MED/94259978
McLean DA; School of Social Work, Syracuse University, New York.
Training African American student leaders as peer educator-mentors to reach African American students in the traditional workshop setting as well as in informal, one-to-one occasions is an effective method of managing students risks of human immunodeficiency virus (HIV) infection. The Ujima project, developed and imp


Blinking and the release reflexes: are they clinically useful?
J Am Geriatr Soc. 1994 Jun;42(6):609-13. Unique Identifier : AIDSLINE MED/94259989
Thomas RJ; Department of Internal Medicine, East Tennessee State University,; Johnson City 37614.
OBJECTIVE: To review the clinical utility of blinking and the release reflexes, palmomental, glabellar, grasp, and snout, as an important part of the bedside neurological examination. DESIGN: Articles published from 1966 to 1993 that addressed blinking or the release reflexes were identified by searching the MEDLINE d


Review of the risk of HIV infection through corneal transplantation in the United States.
J Am Optom Assoc. 1994 Mar;65(3):173-8. Unique Identifier : AIDSLINE MED/94260015
Caron MJ; Wilson R; New England College of Optometry, Boston, MA 02115.
BACKGROUND: Human immunodeficiency virus (HIV), the pathogen that causes acquired immunodeficiency syndrome (AIDS), has been isolated in the corneal epithelium of some HIV-positive patients. This observation raises concern about the risk of HIV transmission through corneal transplantation surgery (penetrating keratopl


Candida tenosynovitis in an AIDS patient: a case report.
J Hand Surg [Am]. 1994 Mar;19(2):293-4. Unique Identifier : AIDSLINE MED/94260052
Townsend DJ; Singer DI; Doyle JR; Department of Surgery, John A. Burns School of Medicine,; University of Hawaii, Honolulu 96813.
Distribution of HIV-contaminated blood prompts closer monitoring of blood supply programs [news]
Infect Control Hosp Epidemiol. 1994 Feb;15(2):132. Unique Identifier : AIDSLINE MED/94260092
Philosophy matters to medicine.
J Med Philos. 1994 Feb;19(1):1-5. Unique Identifier : AIDSLINE MED/94260163
McCullough LB; Center for Ethics, Medicine, and Public Issues, Baylor College of; Medicine, Houston, TX 77030.
Conflicts over post-exposure testing for human immunodeficiency virus: can negotiated settlements help?
J Med Philos. 1994 Feb;19(1):41-59. Unique Identifier : AIDSLINE MED/94260166
Asch DA; Patton JP; Division of General Internal Medicine, University of; Pennsylvania, Philadelphia.
Health care workers with needlestick exposures to patients blood often request a test of the patient for evidence of infection with human immunodeficiency virus. If the patient refuses the test, a conflict develops between the interests of the health care worker and those of the patient. Traditional approaches to thi


The morality of clinical research--a case study.
J Med Philos. 1994 Feb;19(1):7-21. Unique Identifier : AIDSLINE MED/94260168
Tannsjo T; Department of Philosophy, Stockholm University, Sweden.
The paper is a record of a debate which took place between a group of clinicians and the author concerning a clinical trial of a drug supposed to postpone the time when HIV-patients develop AIDS. A problem with the trial was that on available (inconclusive) evidence it appeared that one patient out of 500 was killed b


AIDS-related Kaposi's sarcoma: still a problem, still an opportunity [editorial]
J Clin Oncol. 1994 Jun;12(6):1109-10. Unique Identifier : AIDSLINE MED/94260254
Northfelt DW
Invasive bacterial infections in children born to women infected with human immunodeficiency virus type 1.
J Pediatr. 1994 Jun;124(6):846-52. Unique Identifier : AIDSLINE MED/94260357
Andiman WA; Mezger J; Shapiro E; Department of Pediatrics and Epidemiology, Yale University School; of Medicine, New Haven, Connecticut 06510.
To determine the rates and characteristics of invasive bacterial infections in children infected with the human immunodeficiency virus type 1 (HIV-1), we conducted a prospective, longitudinal, observational cohort study of infants born to HIV-1-infected mothers between Dec. 1, 1985, and Sept. 30, 1989. Of 104 subjects


Invasive pneumococcal disease among infected and uninfected children of mothers with human immunodeficiency virus infection.
J Pediatr. 1994 Jun;124(6):853-8. Unique Identifier : AIDSLINE MED/94260358
Farley JJ; King JC Jr; Nair P; Hines SE; Tressler RL; Vink PE; Department of Pediatrics, University of Maryland School of; Medicine, Baltimore 21201.
OBJECTIVE: To describe the incidence and clinical presentation of invasive pneumococcal disease in a cohort of children infected with human immunodeficiency virus (HIV) who were prospectively followed from birth, in comparison with uninfected children born to HIV-infected mothers and control children. DESIGN: Prospect


Delayed somatic growth and pubertal development in human immunodeficiency virus-infected hemophiliac boys: Hemophilia Growth and Development Study.
J Pediatr. 1994 Jun;124(6):896-902. Unique Identifier : AIDSLINE MED/94260365
Gertner JM; Kaufman FR; Donfield SM; Sleeper LA; Shapiro AD; Howard C; Gomperts ED; Hilgartner MW; Department of Pediatrics, New York Hospital-Cornell Medical; Center, New York 10021.
As part of the Hemophilia Growth and Development Study, we investigated the impact of human immunodeficiency virus (HIV) infection on statural growth, weight gain, and skeletal and sexual maturity in more than 300 boys with moderate to severe hemophilia, of whom 62% were infected with HIV. Age-adjusted height and weig


Multiple folded conformations of a hammerhead ribozyme domain under cleavage conditions.
J Mol Biol. 1994 Jun 10;239(3):366-70. Unique Identifier : AIDSLINE MED/94260543
Woisard A; Fourrey JL; Favre A; Institut Jacques Monod, CNRS-Universite Paris 7, France.
The conformation of a hammerhead ribozyme domain, formed between a 35-mer ribozyme and its 14-mer substrate, was studied under cleavage conditions with non-cleavable substrate analogues. Each analogue substrate contained a single 2 -deoxy-4-thiouridine that formed specific intermolecular crosslinks within the ribozyme


The 1993 distinguished lecturer in substance abuse.
J Subst Abuse Treat. 1994 Jan-Feb;11(1):3-7. Unique Identifier : AIDSLINE MED/94260557
Rosenthal MS
A description of the Maternal Addiction Program of the University of Miami/Jackson Memorial Medical Center.
J Subst Abuse Treat. 1994 Jan-Feb;11(1):55-60. Unique Identifier : AIDSLINE MED/94260560
Malow RM; Ireland SJ; Halpert ES; Szapocznik J; McMahon RC; Haber L; Department of Psychiatry, University of Miami/Jackson Memorial; Medical Center, Florida.
The MAP of the University of Miami/Jackson Memorial Medical Center/Highland Park Pavilion is a comprehensive inpatient and outpatient chemical dependency rehabilitation program that serves mostly lower socioeconomic, African-American perinatal substance-abusing women. The multidisciplinary treatment team incorporates


Dealing with violent behavior among AIDS patients [letter]
J Subst Abuse Treat. 1994 Jan-Feb;11(1):62. Unique Identifier : AIDSLINE MED/94260562
Alter CL; Fornari VM; Deucher R; Chen IL
From the Centers for Disease Control and Prevention. Human immunodeficiency virus transmission in household settings--United States.
JAMA. 1994 Jun 22-29;271(24):1897-9. Unique Identifier : AIDSLINE MED/94260656
A randomized placebo-controlled trial of Saccharomyces boulardii in combination with standard antibiotics for Clostridium difficile disease [published erratum appears in JAMA 1994 Aug 17;272(7):518]
JAMA. 1994 Jun 22-29;271(24):1913-8. Unique Identifier : AIDSLINE MED/94260673
McFarland LV; Surawicz CM; Greenberg RN; Fekety R; Elmer GW; Moyer KA; Melcher SA; Bowen KE; Cox JL; Noorani Z; et al; Department of Medicinal Chemistry, School of Pharmacy, University; of Washington, Seattle 98195.
OBJECTIVE--To determine the safety and efficacy of a new combination treatment for patients with Clostridium difficile-associated disease (CDD). The treatment combines the yeast Saccharomyces boulardii with an antibiotic (vancomycin hydrochloride or metronidazole). DESIGN--A double-blind, randomized, placebo-controlle


HIV/AIDS policies and sports: the National Football League [see comments]
Med Sci Sports Exerc. 1994 Apr;26(4):403-7. Unique Identifier : AIDSLINE MED/94260892
Brown LS Jr; Phillips RY; Brown CL Jr; Knowlan D; Castle L; Moyer J; Department of Medicine, Harlem Hospital/College of Physicians and; Surgeons, Columbia University, New York, NY.
With the assistance of highly respected experts in the field of HIV/AIDS, the NFL has developed a comprehensive policy that should decrease the spread of HIV and any other blood-borne pathogens among its players and medical staff. Transmission of HIV infection is likely to be rare in the NFL. This is supported by the


[Antigenemia and CD4+ cell count in HIV-1 infected patients (letter)]
Medicina (B Aires). 1993;53(5):474-5. Unique Identifier : AIDSLINE MED/94260949
Montero A; Albrecht A; Shujman LE; Suita G; Bartolomeo M; Rozin RH
Genesee County's HIV programs serve as a model for community cooperation.
Mich Med. 1994 Feb;93(2):18-9. Unique Identifier : AIDSLINE MED/94261006
Baker TA
Preventing HIV infection, particularly in women and infants, an urgent public health priority, MDPH reports.
Mich Med. 1994 Feb;93(2):35-6. Unique Identifier : AIDSLINE MED/94261010
Hall WN
Monitoring heterosexual transmission of HIV through testing of antenatal women [editorial] [see comments]
Med J Aust. 1994 Jun 6;160(11):667-8. Unique Identifier : AIDSLINE MED/94261015
Garland S; Kaldor J
Unlinked anonymous screening of antenatal patients for antibody to human immunodeficiency virus type 1 (HIV-1).
Med J Aust. 1994 Jun 6;160(11):693-6. Unique Identifier : AIDSLINE MED/94261022
Chew CB; Downie JC; Cunningham AL; Virology Department, ICPMR, Westmead Hospital, NSW.
OBJECTIVES: To determine the prevalence of HIV-1 infection in the general community by using a target population (antenatal patients) as an indicator of infection, to monitor any change in the prevalence of HIV infection in this population and provide baseline information on heterosexual spread of HIV infection into t


Evidence of HIV transmission in an Australian prison [letter] [see comments]
Med J Aust. 1994 Jun 6;160(11):734. Unique Identifier : AIDSLINE MED/94261042
Dolan K; Hall W; Wodak A; Gaughwin M
Knowledge and practices among injecting-drug users of bleach use for equipment disinfection--New York City, 1993.
MMWR Morb Mortal Wkly Rep. 1994 Jun 24;43(24):439, 445-6. Unique Identifier : AIDSLINE MED/94261099
Sharing (i.e., multiperson use) of drug-injection equipment among injecting-drug users (IDUs) is a major risk factor in the transmission of human immunodeficiency virus (HIV) and other bloodborne pathogens. Abstaining from injection of drugs eliminates this risk; disinfection of needles and syringes with household ble


HIV-1 integrase blocks infection of bacteria by single-stranded DNA and RNA bacteriophages.
Mol Gen Genet. 1994 May 25;243(4):417-25. Unique Identifier : AIDSLINE MED/94261109
Levitz R; Drlica K; Murphy E; Public Health Research Institute, New York, NY 10016.
Expression of human immunodeficiency virus-1 integrase in Escherichia coli, at levels that had no effect on bacterial cell growth, blocked plaque formation by bacteriophages having single-stranded genomic DNA (M13) or RNA (R17, Q beta, PRR1). Plaque formation by phages having double-stranded genomic DNA (T4, PR4) was


Concern over 'invisible problem' of HIV blood in developing countries [news]
Nature. 1994 Jun 9;369(6480):429. Unique Identifier : AIDSLINE MED/94261161
Butler D
Critic still lays blame for AIDS on lifestyle, not HIV [news]
Nature. 1994 Jun 9;369(6480):434. Unique Identifier : AIDSLINE MED/94261167
Dickson D
Disseminated Penicillium marneffei infection as an imported disease in HIV-1 infected patients. Description of two cases and a review of the literature.
Neth J Med. 1994 Jan;44(1):18-22. Unique Identifier : AIDSLINE MED/94261254
Kok I; Veenstra J; Rietra PJ; Dirks-Go S; Blaauwgeers JL; Weigel HM; Department of Internal Medicine, Onze Lieve Vrouwe Gasthuis,; Amsterdam, Netherlands.
Two cases of disseminated Penicillium marneffei infection, as an imported disease, in HIV-1-infected patients with a severe immunodeficiency are reported. These patients had a history of travel in Southeast Asia where P. marneffei is endemic. Fever, cough, malaise, hepatosplenomegaly, anaemia, skin lesions and mucosal


WESTPAC, AIDS, and the Navy [editorial]
Mil Med. 1994 Feb;159(2):171-3. Unique Identifier : AIDSLINE MED/94261308
Wallace D
HIV clinical guidelines [news]
N J Med. 1994 Apr;91(4):203-4. Unique Identifier : AIDSLINE MED/94261320
AIDS [news]
N J Med. 1994 Apr;91(4):208. Unique Identifier : AIDSLINE MED/94261321
Research shows AZT therapy reduces mother-child AIDS transmission [news]
N J Med. 1994 Apr;91(4):274. Unique Identifier : AIDSLINE MED/94261334
Oleske J; Bardequez A
Tuberculous jejunal lymphadenitis in HIV infection [letter]
N Z Med J. 1994 Mar 9;107(973):89-90. Unique Identifier : AIDSLINE MED/94261357
Keating JP; Romeril KR
The unusual nucleotide content of the HIV RNA genome results in a biased amino acid composition of HIV proteins.
Nucleic Acids Res. 1994 May 11;22(9):1705-11. Unique Identifier : AIDSLINE MED/94261442
Berkhout B; van Hemert FJ; Department of Virology, University of Amsterdam, The Netherlands.
Extremely high frequencies of the A nucleotide are found in the RNA genomes of the lentivirus group of retroviruses. It is presently unknown what molecular force is responsible for this A-pressure. In this manuscript, we demonstrate a correlation between this A-pressure and the amino acid-usage of the lentivirus fam


Human immunodeficiency virus type 1 may preferentially integrate into chromatin occupied by L1Hs repetitive elements.
Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5557-61. Unique Identifier : AIDSLINE MED/94261625
Stevens SW; Griffith JD; Department of Microbiology and Immunology, University of North; Carolina, Chapel Hill 27599.
Human DNA flanking sites of eight human immunodeficiency virus type 1 (HIV-1) proviral integrations have been analyzed in isolates derived both from integrations in an infected individual and from tissue culture. Sequence analysis encompassing 80-3000 bp of human DNA on one or both sides of the site of integration rev


Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease.
Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5597-601. Unique Identifier : AIDSLINE MED/94261633
Kaplan AH; Michael SF; Wehbie RS; Knigge MF; Paul DA; Everitt L; Kempf DJ; Norbeck DW; Erickson JW; Swanstrom R; Lineberger Comprehensive Cancer Center, University of North; Carolina, Chapel Hill 27599.
Inhibitors of the human immunodeficiency virus type 1 (HIV-1) protease represent a promising addition to the available agents used to inhibit virus replication in a therapeutic setting. HIV-1 is capable of generating phenotypic variants in the face of a variety of selective pressures. The potential to generate variant


A synthetic retinoid antagonist inhibits the human immunodeficiency virus type 1 promoter [published erratum appears in Proc Natl Acad Sci U S A 1994 Nov 22;91(24):11767]
Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5632-6. Unique Identifier : AIDSLINE MED/94261640
Lee MO; Hobbs PD; Zhang XK; Dawson MI; Pfahl M; Cancer Center, La Jolla Cancer Research Foundation, CA 92037.
Retinoids regulate a broad range of biological processes and affect cell growth and differentiation of many cell types, including the immune system. Recently, it was reported that human immunodeficiency virus type 1 (HIV-1) expression in macrophages is enhanced by retinoic acid (RA). Retinoid signals are mediated by t


Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB.
Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5642-6. Unique Identifier : AIDSLINE MED/94261642
Adya N; Zhao LJ; Huang W; Boros I; Giam CZ; Department of Medicine, Case Western Reserve University School of; Medicine, Cleveland, OH 44106-4984.
The transactivator protein of human T-lymphotropic virus type I (HTLV-I), Tax, forms multiprotein complexes with the ubiquitous transcription factor CREB and the CREB/ATF-1 heterodimer. The interaction between Tax and CREB is highly specific and results in increased binding of the Tax/CREB complexes to the HTLV-I 21-b


Seronegative spondylarthropathies in HIV-infected patients: further evidence of uncommon clinical features.
Rheumatol Int. 1994;13(5):211-3. Unique Identifier : AIDSLINE MED/94261778
Kellner H; Fuessl HS; Herzer P; Medical Policlinic, University of Munich, Germany.
Reiter s syndrome and reactive arthritis in individuals with human immunodeficiency virus (HIV) infection are characterized by severe and persistent arthritis, intense enthesopathy, and poor response to treatment. These uncommon clinical features suggest a direct role of HIV in the pathogenesis of seronegative spondyl


U.N. set to merge AIDS programs [news]
Science. 1994 Jun 10;264(5165):1523. Unique Identifier : AIDSLINE MED/94261821
Immunologic aspects of blood transfusion.
Semin Oncol. 1994 Apr;21(2 Suppl 3):16-20. Unique Identifier : AIDSLINE MED/94261846
Klein HG; Warren G. Magnuson Clinical Center, National Institutes of; Health, Bethesda, MD 20892.
For 20 years, clinical reports and laboratory observations have suggested that allogeneic blood transfusion effects important changes in the recipient s immune response. The seminal clinical studies involved dose-dependent improvement in renal allograft survival in patients transfused with allogeneic whole blood, red


Tolerating reality: the experience of parents of HIV positive sons.
Soc Sci Med. 1994 Apr;38(7):959-71. Unique Identifier : AIDSLINE MED/94261869
Siegl D; Morse JM; School of Nursing, University of Alberta Hospitals, Edmonton.
In this study, the experience of parents as they discover that their son is HIV+ or has AIDS, witness their deterioration and death, is described. Using the methods of grounded theory, 13 parents (8 mothers and 5 fathers) were interviewed and a model depicting the basic social psychological process (BSSP), keeping rea


The geography of AIDS: patterns of urban and rural migration.
South Med J. 1994 Jun;87(6):599-606. Unique Identifier : AIDSLINE MED/94261892
Cohn SE; Klein JD; Mohr JE; van der Horst CM; Weber DJ; Department of Medicine, University of Rochester Medical Center,; NY 14642.
We sought to describe the migration patterns of patients infected with the human immunodeficiency virus (HIV) who seek health services in North Carolina. Of 390 consecutive adult patients with HIV seen at one tertiary care medical center in the southeastern United States in the summer


Toxoplasma gondii pneumonia in patients with the acquired immunodeficiency syndrome: diagnosis by bronchoalveolar lavage.
South Med J. 1994 Jun;87(6):659-63. Unique Identifier : AIDSLINE MED/94261904
Bonilla CA; Rosa UW; Mount Sinai Services, Elmhurst Hospital Center, NY.
We describe the cases of two individuals with advanced AIDS who sought treatment for rapidly progressive respiratory failure due to T gondii pneumonia. The first patient responded to specific therapy after an early diagnosis but died 2 months later of bacterial sepsis. In the second case, the diagnosis was made at aut


Possible use of Betadine in HIV-positive patients.
Ther Hung. 1993;41(3):111-3. Unique Identifier : AIDSLINE MED/94261999
Miskovits E; Gerlei Z; Korchma E; First Department of Medicine, Municipal St Laszlo Hospital,; Budapest.
The results of Betadine treatment obtained in the course of a one-year period proved the usefulness of the bacteriostatic and bactericidal product as a disinfectant of the skin and mucosa in immuno-deficiency diseases, in our cases in AIDS (but supposedly in other similar diseases as well). In these diseases this new


Community acquired lobar pneumonia in patients with HIV infection and AIDS.
Thorax. 1994 Apr;49(4):367-8. Unique Identifier : AIDSLINE MED/94262045
Miller RF; Foley NM; Kessel D; Jeffrey AA; Department of Medicine, University College London Medical School.
BACKGROUND--Community acquired bacterial pneumonia is increasingly encountered in HIV infected individuals and some patients have a radiographic lobar pneumonia. METHODS--A retrospective review of clinical features, microbiological diagnosis, and outcome of community acquired lobar pneumonia was carried out in HIV pos


Tropical respiratory medicine. 1. Pulmonary infections in the tropics: impact of HIV infection.
Thorax. 1994 Apr;49(4):370-8. Unique Identifier : AIDSLINE MED/94262046
Daley CL; Division of Pulmonary and Critical Care Medicine, University of; California, San Francisco 94143-0841.
Multistage carcinogenesis utilizing human genital cells and human papillomaviruses.
Toxicol Lett. 1994 Jun;72(1-3):7-11. Unique Identifier : AIDSLINE MED/94262099
Di Paolo JA; Popescu NC; Ablashi DV; Lusso P; Zimonjic DB; Woodworth CD; National Cancer Institute, Laboratory of Biology, Bethesda, MD; 20892.
The preponderance of evidence indicates that a subset of human papillomaviruses are important etiological agents for cervical cancer. However, the necessity of other agents as well as cellular events is recognized because not all women with papillomaviruses develop cancer. Therefore, the exact role of papillomaviruses


gag- and env-specific serum antibodies in cats after natural and experimental infection with feline immunodeficiency virus.
Vet Microbiol. 1994 Mar;39(1-2):153-65. Unique Identifier : AIDSLINE MED/94262283
Rimmelzwaan GF; Siebelink KH; Broos H; Drost GA; Weijer K; van Herwijnen R; Osterhaus AD; Laboratory of Immunobiology, National Institute of Public Health; and Environmental Protection, Bilthoven, Netherlands.
In order to monitor the antibody response to feline immunodeficiency virus (FIV) in cats, following experimental and natural infection, enzyme-linked immunosorbent assays (ELISAs) were developed using recombinant env and gag proteins and p24-specific monoclonal antibodies. It was shown that in experimentally infected


Antibody response to Brucella melitensis outer membrane antigens in naturally infected and Rev1 vaccinated sheep.
Vet Microbiol. 1994 Mar;39(1-2):33-46. Unique Identifier : AIDSLINE MED/94262288
Zygmunt MS; Debbarh HS; Cloeckaert A; Dubray G; Laboratoire de Pathologie Infectieuse et Immunologie, Institut; National de la Recherche Agronomique, Nouzilly, France.
Sera from Brucella infected and B. melitensis Rev1 vaccinated sheep were analysed by immunoblotting using the cell envelope fraction (CEF) of B. melitensis B115. The CEF of B. melitensis B115 was analysed using a bank of monoclonal antibodies. The fraction consisted mainly of S-LPS like molecules, R-LPS and outer memb


ACP and IDSA issue statement on human immunodeficiency virus infection.
Am Fam Physician. 1994 Jun;49(8):1972-4. Unique Identifier : AIDSLINE MED/94262558
AIDS in heterosexuals [news]
Am Fam Physician. 1994 Jun;49(8):1982. Unique Identifier : AIDSLINE MED/94262560
HIV wasting. How to stop the cycle.
Am J Nurs. 1994 Jun;94(6):18-24; quiz 25. Unique Identifier : AIDSLINE MED/94262638
Anastasi JK; Lee VS; Columbia University School of Nursing, New York.
Donor insemination and human immunodeficiency virus: a risk/benefit analysis.
Am J Obstet Gynecol. 1994 Jun;170(6):1692-6; discussion 1696-8. Unique Identifier : AIDSLINE MED/94262665
Nachtigall RD; Department of Obstetrics, Gynecology and Reproductive Science,; University of California, San Francisco.
In 1988 the American Fertility Society revised its guidelines for the use of semen in donor insemination by stating that the use of fresh semen for donor insemination is no longer warranted. Although the consequences of this recommendation include an approximate doubling of the patient s cost of treatment, a 50% reduc


HIV-1 nucleic acids localize to the spermatogonia and their progeny. A study by polymerase chain reaction in situ hybridization.
Am J Pathol. 1994 Jun;144(6):1142-8. Unique Identifier : AIDSLINE MED/94262692
Nuovo GJ; Becker J; Simsir A; Margiotta M; Khalife G; Shevchuk M; Department of Pathology, SUNY at Stony Brook 11794-8691.
The purpose of this study was to determine the histological distribution of in situ polymerase chain reaction (PCR)-amplified HIV-1 nucleic acids in the male genital tract to elucidate the mechanism of sexual transmission of AIDS. Viral DNA was detected in the testicular tissue of 11 of 12 men with HIV-1 infection usi


Early stages of simian immunodeficiency virus infection in lymph nodes. Evidence for high viral load and successive populations of target cells.
Am J Pathol. 1994 Jun;144(6):1226-37. Unique Identifier : AIDSLINE MED/94262702
Chakrabarti L; Isola P; Cumont MC; Claessens-Maire MA; Hurtrel M; Montagnier L; Hurtrel B; Unite d'Oncologie Virale, Institut Pasteur, Paris, France.
Lymph nodes obtained from 14 macaques sacrificed at early time points following experimental inoculation with simian immunodeficiency virus were analyzed by in situ hybridization for virus load and virus cellular tropism. The lymph nodes presented a remarkably high viral load during the early phase of infection, as vi


Viral gene products and replication of the human immunodeficiency type 1 virus.
Am J Physiol. 1994 May;266(5 Pt 1):C1135-56. Unique Identifier : AIDSLINE MED/94262722
Morrow CD; Park J; Wakefield JK; Department of Microbiology, University of Alabama at Birmingham; 35294.
The acquired immunodeficiency syndrome (AIDS) epidemic represents a modern-day plague that has not only resulted in a tragic loss of people from a wide spectrum of society but has reshaped our viewpoints regarding health care, the treatment of infectious diseases, and social issues regarding sexual behavior. There is


Health insurance coverage among persons with AIDS: results from a multistate surveillance project.
Am J Public Health. 1994 Jun;84(6):1015-8. Unique Identifier : AIDSLINE MED/94262950
Diaz T; Chu SY; Conti L; Nahlen BL; Whyte B; Mokotoff E; Shields A; Checko PJ; Herr M; Mukhtar Q; et al; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, Ga. 30333.
To determine factors associated with health insurance coverage among persons with acquired immunodeficiency syndrome (AIDS), we interviewed 1958 persons 18 years of age or older who were reported to have AIDS in 11 states and cities. Overall, 25% had no insurance, 55% had public insurance, and 20% had private insuranc


The protective effect of nonoxynol-9 against HIV infection [letter] [see comments]
Am J Public Health. 1994 Jun;84(6):1032-4. Unique Identifier : AIDSLINE MED/94262956
Feldblum PJ; Weir SS
Formulating public health policy: the case of AIDS [editorial; comment] [see comments]
Am J Public Health. 1994 Jun;84(6):888-9. Unique Identifier : AIDSLINE MED/94262960
Gebbie KM
The urgent need for a vaginal microbicide in the prevention of HIV transmission [editorial; comment]
Am J Public Health. 1994 Jun;84(6):890-1. Unique Identifier : AIDSLINE MED/94262961
Potts M
AIDS prevention and cultural sensitivity: are they compatible? [see comments]
Am J Public Health. 1994 Jun;84(6):895-8. Unique Identifier : AIDSLINE MED/94262964
Bayer R; Division of Sociomedical Sciences, School of Public Health,; Columbia University, New York, NY 10032.
The role of state health departments in formulating policy: a survey on the case of AIDS [see comments]
Am J Public Health. 1994 Jun;84(6):905-9. Unique Identifier : AIDSLINE MED/94262966
Robins L; Backstrom C; Public Administration Program, Roosevelt University, Chicago,; Ill.
OBJECTIVES. Public health departments have been criticized for not being on the cutting edge of health policy formation in the United States and, in particular, for being ineffective in dealing with acquired immunodeficiency syndrome (AIDS). This study examines the attitudes and influe


Are bisexually identified men in San Francisco a common vector for spreading HIV infection to women?
Am J Public Health. 1994 Jun;84(6):915-9. Unique Identifier : AIDSLINE MED/94262968
Ekstrand ML; Coates TJ; Guydish JR; Hauck WW; Collette L; Hulley SB; Center for AIDS Prevention Studies, University of California, San; Francisco.
OBJECTIVES. This article examines sexual risk taking among self-identified bisexual men in San Francisco and whether risk reduction has occurred, with respect to both homosexual and heterosexual behaviors, among human immunodeficiency virus (HIV) antibody-positive and HIV antibody-negative men. It also examines psycho


Correlates of needle sharing among injection drug users.
Am J Public Health. 1994 Jun;84(6):920-3. Unique Identifier : AIDSLINE MED/94262969
Mandell W; Vlahov D; Latkin C; Oziemkowska M; Cohn S; Department of Mental Hygiene, Johns Hopkins School of Hygiene and; Public Health, Baltimore, MD 21205.
OBJECTIVES. The sharing of contaminated injection equipment is the primary mode of human immunodeficiency virus (HIV) transmission for injection drug users. This study examined demographic factors, life events, and drug use practices that are potential risk factors for sharing injection equipment. METHODS. Between Feb


Why did black life expectancy decline from 1984 through 1989 in the United States? [see comments]
Am J Public Health. 1994 Jun;84(6):938-44. Unique Identifier : AIDSLINE MED/94262972
Kochanek KD; Maurer JD; Rosenberg HM; Mortality Statistics Branch, National Center for Health; Statistics, Hyattsville, MD 20782.
OBJECTIVES. The objective of this study was to partition the change in US life expectancy into those major causes of death and age groups that contributed most to the decline in life expectancy for Black males and females and to the increase in life expectancy for White males and females in the period from 1984 throug


Social influences on the sexual behavior of youth at risk for HIV exposure.
Am J Public Health. 1994 Jun;84(6):977-85. Unique Identifier : AIDSLINE MED/94262978
Romer D; Black M; Ricardo I; Feigelman S; Kaljee L; Galbraith J; Nesbit R; Hornik RC; Stanton B; Center for International, Health, and Development Communication,; Annenberg School for Communication, University of Pennsylvania,; Philadelphia 19104.
OBJECTIVES. Adolescents are increasingly at risk for infection with human immunodeficiency virus (HIV) and other sexually transmitted diseases, especially in poor urban minority communities. To aid the design of interventions in these communities, this study investigated the role of knowledge, attitudes, perceived par


Human immunodeficiency virus infection and cryptosporidiosis: protective immune responses.
Am J Trop Med Hyg. 1994;50(5 Suppl):29-35. Unique Identifier : AIDSLINE MED/94263005
Flanigan TP; Miriam Hospital, Providence, Rhode Island.
Cryptosporidium parvum is an ubiquitous protozoan parasite that infects the gastrointestinal track, leading to enteritis. The course of the disease is closely linked to the immunocompetence of the host. In patients with human immunodeficiency virus (HIV) infections, the CD4 cell count is the best marker of the ability


Detection of HIV1 DNA in biological samples by an homogeneous assay: fluorescence measurement of double-stranded RNA synthesized from amplified DNA.
Anal Biochem. 1994 Mar;217(2):248-54. Unique Identifier : AIDSLINE MED/94263047
Livache T; Fouque B; Teoule R; Cis Bio International Laboratoire des Sondes Moleculaires, Gif; sur Yvette, France.
A nonisotopic homogeneous detection of nucleic acid sequences after amplification is described. We show that a DNA fragment bearing T7 RNA polymerase promoters on each extremity is able to be transcribed in two complementary RNAs, leading to a high yield direct synthesis of double-stranded RNA (dsRNA). Thus, this dsRN


The paradox of HIV/AIDS as expanding consciousness.
ANS Adv Nurs Sci. 1994 Mar;16(3):13-21. Unique Identifier : AIDSLINE MED/94263129
Lamendola FP; Newman MA; School of Nursing, University of Minnesota, Minneapolis.
A heuristic approach employing Newman s method for pattern identification was used to examine the theory of health as expanding consciousness in persons with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). Themes derived from the interview of nine gay men portrayed a pattern of alienation


Pharmacokinetics of antiviral polyoxometalates in rats.
Antimicrob Agents Chemother. 1994 Mar;38(3):504-10. Unique Identifier : AIDSLINE MED/94263151
Ni L; Boudinot FD; Boudinot SG; Henson GW; Bossard GE; Martellucci SA; Ash PW; Fricker SP; Darkes MC; Theobald BR; et al; Department of Pharmaceutics, College of Pharmacy, University of; Georgia, Athens 30602.
Polyoxometalates are soluble mineral compounds formed principally of oxide anions and early transition metal cations. The polyoxometalates K12H2[P2W12O48].24H2O (JM 1591), K10[P2W18Zn4(H2O)2O68].20H2O (JM 1596), and [(CH3)3NH]8[Si2W18Nb6O77] (JM 2820) demonstrate potent antiviral activity against human immunodeficienc


Impact of dosing schedule upon suppression of a retrovirus in a murine model of AIDS encephalopathy.
Antimicrob Agents Chemother. 1994 Mar;38(3):628-31. Unique Identifier : AIDSLINE MED/94263174
Bilello JA; Eiseman JL; Standiford HC; Drusano GL; Department of Microbiology and Immunology, University of Maryland; Cancer Center, Baltimore.
We studied the impact of zidovudine ( AZT ) in Cas-Br-M murine leukemia virus-infected NFS-N mice after administration by once-daily bolus or continuous infusion. While higher peak concentrations of AZT were achieved by once-daily dosing, continuous AZT


Psychological distress in family members living with human immunodeficiency virus/acquired immune deficiency syndrome [published erratum appears in Arch Psychiatr Nurs 1994 Jun;8(3):209]
Arch Psychiatr Nurs. 1994 Feb;8(1):53-61. Unique Identifier : AIDSLINE MED/94263265
McShane RE; Bumbalo JA; Patsdaughter CA; School of Nursing, University of Wisconsin-Milwaukee 53201.
This article describes the psychological distress experienced by family members living with human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS). Survey data were collected from 133 individuals, (47 parents, 53 siblings, 33 adult family members who have HIV/AIDS) representing 80 families. In-dep


Wider meaning for lactate dehydrogenase in acquired immunodeficiency syndrome [letter]
Arch Intern Med. 1994 Jun 13;154(11):1296, 1298. Unique Identifier : AIDSLINE MED/94263321
Romo-Garcia J; Salido Rengell F
Pulmonary veno-occlusive disease. Another vascular disorder associated with human immunodeficiency virus infection?
Arch Pathol Lab Med. 1994 Jun;118(6):664-6. Unique Identifier : AIDSLINE MED/94263344
Ruchelli ED; Nojadera G; Rutstein RM; Rudy B; Department of Pathology, Children's Hospital of Philadelphia, PA; 19104.
A variety of arterial lesions in both pulmonary and systemic circulations have been described in association with human immunodeficiency virus infection. Such lesions include plexogenic arteriopathy in patients with primary pulmonary hypertension and fibrocalcific arterial lesions described in a variety of organs. Les


Inhibition of the in vitro integration of Moloney murine leukemia virus DNA by the DNA minor groove binder netropsin.
Biochem Pharmacol. 1994 May 18;47(10):1821-6. Unique Identifier : AIDSLINE MED/94263434
Carteau S; Mouscadet JF; Goulaouic H; Subra F; Auclair C; Laboratoire de Physicochimie et Pharmacologie des Macromolecules; Biologiques, CNRS URA 147, Institut Gustave Roussy, Villejuif,; France.
In search of potential inhibitors of integration of retroviral DNA into host cells genome, we have investigated the effect of the external DNA binder netropsin on the in vitro insertion of long terminal repeat (LTR) ends of Moloney murine leukemia virus (M.MuLV) as catalysed by integrase purified from baculovirus stra


Effect of ethanol on the interaction between the macrophage and Mycobacterium avium.
Alcohol. 1994 Mar-Apr;11(2):69-73. Unique Identifier : AIDSLINE MED/94263472
Bermudez LE; Kuzell Institute for Arthritis and Infectious Diseases,; California Pacific Medical Center Research Institute, San; Francisco 94115.
Chronic ethanol ingestion predisposes to tuberculosis and bacterial pneumonia. Mycobacterium avium complex organisms cause bacteremia in patients with AIDS. Human macrophages and murine Kupffer cells exposed to ethanol are more permissive towards intracellular growth of M. avium than control mononuclear phagocytes. Et


Ethanol, immune responses, and murine AIDS: the role of vitamin E as an immunostimulant and antioxidant.
Alcohol. 1994 Mar-Apr;11(2):75-84. Unique Identifier : AIDSLINE MED/94263473
Wang Y; Watson RR; Nutritional Sciences Program, University of Arizona, Tucson; 85724.
Excessive alcohol consumption is a major health problem in the United States . Prolonged consumption of alcohol results in alterations of immune responses, ultimately manifested by increasing susceptibility to infectious agents. Such changes can be due to the direct effects of alcohol o


Selective effect of alcohol on cellular immune responses of lymphocytes from AIDS patients.
Alcohol. 1994 Mar-Apr;11(2):85-90. Unique Identifier : AIDSLINE MED/94263474
Nair MP; Kumar NM; Kronfol ZA; Saravolatz LA; Pottathil R; Greden JF; Schwartz SA; Department of Medicine, State University of New York at Buffalo.
In this study we examined the in vitro effects of alcohol on the proliferative responses of lymphocytes from healthy donors and AIDS patients to a recombinant fusion peptide, env-gag, corresponding to portions of the gp41 envelope (env) and internal core (gag) proteins of HIV. The effects of alcohol (ETOH) on the natu


Human studies on alcohol and susceptibility to HIV infection.
Alcohol. 1994 Mar-Apr;11(2):99-103. Unique Identifier : AIDSLINE MED/94263476
Balla AK; Lischner HW; Pomerantz RJ; Bagasra O; University of Oklahoma Health Sciences Center, Department of; Pathology, Oklahoma City 73190.
Here we review existing evidence that alcohol intake may influence the susceptibility to human immunodeficiency virus type 1 (HIV-1) infection and the effect that alcohol may have on accelerating the onset of AIDS after the initial infection. Possible immunological and psychosocial mechanisms to explain the increased


[Influence of hepatitis C virus infection and human immunodeficiency on the natural history of chronic delta hepatitis]
Rev Esp Enferm Dig. 1994 Mar;85(3):185-91. Unique Identifier : AIDSLINE MED/94263696
Crespo J; Lozano JL; Echevarria S; San Miguel G; Artinano E; Lopez Arias MJ; Pons Romero F; Servicio de Aparato Digestivo, Hospital Universitario, Marques; de Valdecilla.
OBJECTIVES: To analyze the prevalence and clinical significance of HCV an HIV infections among a group of patients with chronic delta hepatitis. METHODS: We have studied the clinical and the histological activity and the serological profile the HBV DNA was analyzed by dot blot and PCR and the HDV RNA by dot blot) in 4


Bacillary angiomatosis in a patient with lymphocytic leukaemia.
Br J Dermatol. 1994 May;130(5):665-8. Unique Identifier : AIDSLINE MED/94263802
Torok L; Viragh SZ; Borka I; Tapai M; Department of Dermatology, Bacs-Kiskun Country Hospital,; Kecskemet, Hungary.
A 78-year-old man, who suffered from chronic lymphocytic leukaemia and diabetes mellitus, but was human immunodeficiency virus (HIV)-negative, developed disseminated angiomatous papules following a cat scratch. Bacillary angiomatosis was diagnosed by light and electron microscopic demonstration of the causative bacter


HIV protease as an inhibitor target for the treatment of AIDS.
Adv Pharmacol. 1994;25:399-454. Unique Identifier : AIDSLINE MED/94263833
Darke PL; Huff JR; Department of Biological Chemistry, Merck Research Laboratories,; West Point, Pennsylvania 19486.
Lymphoma complicating immunodeficiency disorders.
Ann Oncol. 1994;5 Suppl 2:29-35. Unique Identifier : AIDSLINE MED/94263852
Levine AM; University of Southern California School of Medicine, Los; Angeles.
BACKGROUND: An increased incidence of lymphoma is seen in various types of immune deficiency or dysregulation, including congenital immune deficiency diseases, organ transplantation with iatrogenic immunosuppression, autoimmune disorders, endemic Burkitt s lymphoma, and AIDS-associated lymphoma. RESULTS: The lymphomas


Hodgkin's disease in patients with HIV infection and in the general population: comparison of clinicopathological features and survival.
Ann Oncol. 1994;5 Suppl 2:37-40. Unique Identifier : AIDSLINE MED/94263853
Errante D; Zagonel V; Vaccher E; Serraino D; Bernardi D; Sorio R; Trovo M; Carbone A; Monfardini S; Tirelli U; Division of Medical Oncology and AIDS, Centro di Riferimento; Oncologico, Aviano, Italy.
BACKGROUND: Hodgkin s disease (HD) has been described in patients with HIV infection in association with unfavourable prognostic factors. Similarly, HD in the older general population has a poorer prognosis than in younger patients. PATIENTS AND METHODS: With the aim of comparing the clinicopathological features and s


Stage, serum LDH, and performance status predict disease progression and survival in HIV-associated lymphomas.
Ann Oncol. 1994;5 Suppl 2:41-6. Unique Identifier : AIDSLINE MED/94263854
Hagemeister FB; Khetan R; Allen P; McLaughlin P; Rodriguez MA; Swan F Jr; Romaguera JE; Cabanillas F; Department of Hematology, University of Texas M. D. Anderson; Cancer Center, Houston.
PURPOSE: This is a review of treatment of 44 patients with positive HIV serology (positive HIV) and lymphoma. MATERIALS AND METHODS: Twenty patients had diffuse large-cell lymphoma (DLCL), and 18 had small noncleaved-cell lymphoma (SNCCL). Three had Hodgkin s disease (HD) and 3 had diffuse small- or mixed-cell lymphom


Structure, synthesis, and activity of dermaseptin b, a novel vertebrate defensive peptide from frog skin: relationship with adenoregulin.
Biochemistry. 1994 May 31;33(21):6642-50. Unique Identifier : AIDSLINE MED/94263975
Mor A; Amiche M; Nicolas P; Laboratoire de Bioactivation des Peptides, Institut Jacques; Monod, CRNS-Universite Paris 7.
A novel antimicrobial peptide, designated dermaseptin b, was isolated from the skin of the arboreal frog Phyllomedusa bicolor. This 27-residue peptide amide is basic, containing 3 lysine residues that punctuate an alternating hydrophobic and hydrophilic sequence. In helix-inducing solvent, dermaseptin b adopts an amph


Predictors of intoxicated sex in injecting drug users.
J Addict Dis. 1994;13(2):69-80. Unique Identifier : AIDSLINE MED/94264066
Ross MW; Kelaher M; Wodak A; Gold J; Center for Health Promotion Research and Development, School of; Public Health, University of Texas at Houston 77225.
Transmission of HIV by sexual contact as well as through sharing of contaminated injection equipment is a source of viral spread from injecting drug users (IDUs). We report on an analysis of data from 1,245 IDUs interviewed in Sydney, Australia in which half of the respondents r


Falling incidence of HIV infection in a cohort of clinic attenders [published erratum appears in Aust J Public Health 1994 Mar;18(1):118]
Aust J Public Health. 1993 Dec;17(4):334-8. Unique Identifier : AIDSLINE MED/94264111
Kaldor J; Williamson P; Guinan JJ; Imrie A; Gold J; National Centre in HIV Epidemiology and Clinical Research,; University of NSW, Sydney.
It is widely accepted that changes in sexual behaviour in the mid-1980s drastically reduced the spread of human immunodeficiency virus (HIV) through male homosexual contact in Western countries, but documentation of changes in infection rates has been based on observation of subjects enrolled in cohort studies, who ma


Report from Berlin: ninth AIDS conference--prevention.
Aust J Public Health. 1993 Dec;17(4):390-2. Unique Identifier : AIDSLINE MED/94264122
Kelaher M; National Drug and Alcohol Research Centre, University of New; South Wales, Sydney.
Comparison of the Rev transactivation of feline immunodeficiency virus in feline and non-feline cell lines.
J Vet Med Sci. 1994 Feb;56(1):199-201. Unique Identifier : AIDSLINE MED/94264157
Tomonaga K; Miyazawa T; Kawaguchi Y; Kohmoto M; Inoshima Y; Mikami T; Department of Veterinary Microbiology, Faculty of Agriculture,; University of Tokyo, Japan.
The Rev protein of feline immunodeficiency virus (FIV) differentially transactivates the expression of viral structural proteins by allowing the accumulation of unspliced and singly spliced viral mRNA in cytoplasm via the Rev response element (RRE) at the end of env. To investigate the role of rev gene of FIV for the


Disease due to the Mycobacterium avium complex in patients with AIDS: epidemiology and clinical syndrome.
Clin Infect Dis. 1994 Apr;18 Suppl 3:S218-22. Unique Identifier : AIDSLINE MED/94264183
Benson CA; Department of Medicine, Rush Medical; College/Rush-Presbyterian-St. Luke's Medical Center, Chicago,; Illinois 60612.
Infection due to the Mycobacterium avium complex (MAC) is the most common opportunistic disease of bacterial origin among patients with AIDS in the United States . The incidence of disseminated disease due to MAC (DMAC) has risen dramatically in recent years. The risk of developing DMAC


Prophylaxis of Mycobacterium avium complex bacteremia in patients with AIDS.
Clin Infect Dis. 1994 Apr;18 Suppl 3:S223-6. Unique Identifier : AIDSLINE MED/94264184
Gordin F; Masur H; Division of Infectious Diseases, Veterans Administration Medical; Center, Washington, D.C. 20422.
Prevention of opportunistic infections is an integral part of caring for patients infected with human immunodeficiency virus. Mycobacterium avium complex (MAC) bacteremia can cause severe morbidity and excess mortality among these patients. Controlled trials of rifabutin for the prophylaxis of MAC bacteremia have been


Assessment of new therapies for infection due to the Mycobacterium avium complex: appropriate use of in vitro and in vivo testing.
Clin Infect Dis. 1994 Apr;18 Suppl 3:S233-6. Unique Identifier : AIDSLINE MED/94264186
Grosset JH; Department of Bacteriology and Virology, Groupe Hospitalier,; Paris, France.
Laboratory testing is a prerequisite to predictions about the potential value of human clinical trials--the gold standard for the assessment of new therapies for infection with the Mycobacterium avium complex (MAC). These laboratory assessments must be made in the proper sequence, with appropriate models and methodolo


Treatment of disseminated disease due to the Mycobacterium avium complex in patients with AIDS.
Clin Infect Dis. 1994 Apr;18 Suppl 3:S237-42. Unique Identifier : AIDSLINE MED/94264187
Benson CA; Department of Medicine, Rush Medical; College/Rush-Presbyterian-St. Luke's Medical Center, Chicago,; Illinois 60612.
Perhaps the most important recent advance in the field of infections due to the Mycobacterium avium complex (MAC) is the identification and development of more effective agents for the treatment and prevention of disseminated disease. These agents include clarithromycin, azithromycin, rifabutin and other rifamycins, e


[Preparing bifunctional antibodies to human IGG and horseradish peroxidase and their utilization for testing of antibodies to HIV]
Biull Eksp Biol Med. 1994 Mar;117(3):291-3. Unique Identifier : AIDSLINE MED/94264276
Massino IuS; Sukhanova LL; Kizim EA; Segal OL; Smirnova MB; Monakhov VV; Koliaskina GI; Dmitriev AD
Molecular characterization of CD30+ anaplastic large-cell lymphoma: high frequency of c-myc proto-oncogene activation.
Blood. 1994 Jun 15;83(12):3581-90. Unique Identifier : AIDSLINE MED/94264311
Inghirami G; Macri L; Cesarman E; Chadburn A; Zhong J; Knowles DM; Division of Surgical Pathology, College of Physicians and; Surgeons of Columbia University, New York, NY.
Anaplastic large-cell lymphoma (ALCL) represents a morphologically distinct type of non-Hodgkin s lymphoma (NHL) characterized phenotypically by the expression of the CD30 antigen, a new member of the nerve growth factor gene family. The lymphoid origin of ALCL has been documented


Circulating immune profile in patients with pre-cancer and cancer of the cervix: a cross sectional study among Indian women.
Bull Cancer (Paris). 1993 Oct;80(10):852-6. Unique Identifier : AIDSLINE MED/94264425
Gupta MM; Jain R; Parashari A; Singh V; Sharma S; Division of Immunology and Virology, Institute of Cytology &; Preventive Oncology (ICMR), India.
To fully understand immune competence in subjects with precancerous and cancerous lesions of the uterine cervix, various markers of T and B cells in peripheral blood were evaluated. The cellular measures were the absolute numbers of CD2, CD3, CD22, CD25, CD4, CD8 and CD4/CD8 T cell ratio and serologic measures were th


Reactive arthritis. May develop in patients with HIV infection [letter; comment]
BMJ. 1994 May 14;308(6939):1302. Unique Identifier : AIDSLINE MED/94264567
Winceslaus SJ
Evaluation of lymphadenopathy in children.
Curr Opin Pediatr. 1994 Feb;6(1):68-76. Unique Identifier : AIDSLINE MED/94264746
Grossman M; Shiramizu B; University of California, San Francisco.
This chapter provides an approach to the evaluation of lymphadenopathy in children. Malignant etiologies, including HIV-associated malignancies are reviewed. In discussing infectious agents or causes of lymphadenopathy, particular emphasis is placed on chronic regional lymphadenopathy with a focus on new advances in c


Skeletal infections in children.
Curr Opin Pediatr. 1994 Feb;6(1):90-3. Unique Identifier : AIDSLINE MED/94264750
Hughes LO; Aronson J; Department of Pediatric Orthopedics, Arkansas Children's; Hospital, Little Rock 72202-3591.
Bacteremia is an almost daily occurrence in childhood. Fortunately, infections in children are usually easily controlled and seldom produce serious sequelae. The prompt diagnosis and treatment of osteomyelitis is especially important to prevent catastrophic complications. Recent articles have pointed out that fine-nee


Ethics, epidemiology, and women's health.
Ann Epidemiol. 1994 Mar;4(2):159-65. Unique Identifier : AIDSLINE MED/94264865
Levine C; Orphan Project, New York, NY 10013.
Ethical issues arise throughout the conduct of epidemiologic studies, in the processes of determining the study question, designing the protocol, and implementing the study. There also is an ethical dimension when studies are not done, for example, in studies of the effect of drugs and chemicals on male reproductive c


Transcriptional elongation by RNA polymerase II is stimulated by transactivators.
Cell. 1994 Jun 3;77(5):749-59. Unique Identifier : AIDSLINE MED/94265264
Yankulov K; Blau J; Purton T; Roberts S; Bentley DL; Molecular Genetics of Differentiation Laboratory, Imperial Cancer; Research Fund, Lincoln's Inn Fields, London, England.
We report that a variety of transactivators stimulate elongation by RNA polymerase II. Activated transcription complexes have high processivity and are able to read through pausing and termination sites efficiently. In contrast, nonactivated and squelched transcription mostly arrests prematurely. Activators differ in


AIDS-related fear: beliefs, attitudes, behaviors.
CDS Rev. 1993 Mar;86(2):18-23. Unique Identifier : AIDSLINE MED/94265267
Horowitz LG; Cohen P; Lewis PL
Global tuberculosis incidence and mortality during 1990-2000.
Bull World Health Organ. 1994;72(2):213-20. Unique Identifier : AIDSLINE MED/94265282
Dolin PJ; Raviglione MC; Kochi A; Imperial Cancer Research Fund, Radcliffe Infirmary, University of; Oxford, England.
Forecasts of tuberculosis morbidity and mortality are presented for the decade 1990-99. An estimated 88 million new cases of tuberculosis, of which 8 million will be attributable to HIV infection, will occur in the world during the decade; 30 million people are predicted to die of tuberculosis in the same period, incl


Quality of sexually transmitted disease services in Jamaica: evaluation of a clinic-based approach. Collaborative Working Group on Indicators of STD Case Management.
Bull World Health Organ. 1994;72(2):239-47. Unique Identifier : AIDSLINE MED/94265286
Bryce J; Vernon A; Brathwaite AR; Perry S; Figueroa JP; Emerson RB; Social and Behavioral Sciences Branch, Technical Support; Division, Centers for Disease Control and Prevention, Atlanta, GA; 30333.
As part of a larger strategy to develop global indicators of HIV (human immunodeficiency virus) infection prevention programmes, a clinic-based method for the assessment of sexually transmitted disease (STD) service quality was developed and field tested by trained observers who visited a random sample of public-secto


Tuberculosis preventive therapy in HIV-infected individuals [news]
Bull World Health Organ. 1994;72(2):305-7, 309-11. Unique Identifier : AIDSLINE MED/94265292
Pulmonary hypertension in patients with human immunodeficiency virus infection. Comparison with primary pulmonary hypertension.
Circulation. 1994 Jun;89(6):2722-7. Unique Identifier : AIDSLINE MED/94265329
Petitpretz P; Brenot F; Azarian R; Parent F; Rain B; Herve P; Simonneau G; Hopital Antoine Beclere, Clamart, France.
BACKGROUND: Previously reported cases of patients with pulmonary hypertension (PH) and human immunodeficiency virus (HIV) infection are poorly documented regarding baseline hemodynamics and potential for pulmonary vasodilatation. The purpose of this report was to compare HIV-infected patients who had PH with non-HIV-i


Two organizations develop new HIV early intervention guidelines [news]
Colo Med. 1994 Apr;91(4):158. Unique Identifier : AIDSLINE MED/94265389
[The use of intravenous 7S immunoglobulins at high doses in HIV-related immunological pathology]
Clin Ter. 1994 Apr;144(4):301-5. Unique Identifier : AIDSLINE MED/94265402
Fiori GP; Divisione di Malattie Infettive, Ospedale Multizonale di Varese.
24 AIDS patients, both males and females, aged from 3 to 52 years, received high-dose i.v. 7S immunoglobulin (220-400 mg/kg, range 7.5-20 g/die). These patients were affected by HIV-related thrombocytopenia and antibiotic-resistant severe hyperpyrexia; three HIV-positive asymptomatic children with severe immunodeficie


Controlled utilization of induced sputum analysis in the diagnosis of Pneumocystis carinii pneumonia.
Chest. 1994 Jun;105(6):1770-4. Unique Identifier : AIDSLINE MED/94265541
Wehner JH; Jensen WA; Kirsch CM; Kagawa FT; Campagna AC; Stanford University School of Medicine, Division of Pulmonary and; Critical Care Medicine, Calif.
We investigated the outcome and potential cost savings of a system designed to limit physician access to induced sputum analysis (ISA) for the diagnosis of Pneumocystis carinii pneumonia (PCP). Four respiratory medicine physicians screened all requests for ISA to determine the pretest likelihood of PCP. Twenty-two of


Recovery of viruses other than cytomegalovirus from bronchoalveolar lavage fluid [see comments]
Chest. 1994 Jun;105(6):1775-81. Unique Identifier : AIDSLINE MED/94265542
Connolly MG Jr; Baughman RP; Dohn MN; Linnemann CC Jr; Department of Internal Medicine, University of Cincinnati Medical; Center.
STUDY DESIGN: To determine the yield and diagnostic significance of performing viral cultures on specimens obtained by bronchoalveolar lavage (BAL) in immunocompromised patients. DESIGN: Review of all BAL specimens submitted for viral culture over a six-year period. SETTING: Referral laboratory within a university hos


Relationships between structure and antiretroviral activity of thiosemicarbazone derivatives.
Chemotherapy. 1994 May-Jun;40(3):195-200. Unique Identifier : AIDSLINE MED/94265614
Teitz Y; Barko N; Abramoff M; Ronen D; Department of Human Microbiology, Sackler School of Medicine, Tel; Aviv University, Israel.
In an attempt to develop anti-AIDS drugs, the compound isatin beta-thiosemicarbazone has been subjected to systematic structural modifications. The resulting synthesized thiosemicarbazone derivatives (TSCDs) were examined for their ability to act as antiretrovirus agents in a model system--2M3/M cell system--consistin


[The problem of recurrence of enzootic bovine leukosis in previously cured herds]
DTW Dtsch Tierarztl Wochenschr. 1994 Apr;101(4):158-62. Unique Identifier : AIDSLINE MED/94265654
Lorenz RJ; Straub OC; Bundesforschungsanstalt fur Viruskrankheiten der Tiere,; Tubingen.
Within nine months, enzootic bovine leukosis (EBL) occurred in 23 well documented herds. Eight of them (= 35%) had previously conducted the eradication programme as laid down by law. This proportion is tenfold higher than anticipated from the average incidence rate since 1978. The conclusion is drawn that a higher ris


AIDS and gastrointestinal endoscopy.
Endoscopy. 1994 Jan;26(1):175-84. Unique Identifier : AIDSLINE MED/94265708
Dancygier H; Department of Internal Medicine II, Municipal Hospital Offenbach,; J. W. Goethe University, Frankfurt am Main, Germany.
Human papillomavirus infections of the genital region in human immunodeficiency virus seropositive women: integration of type 16 correlates with rapid progression.
Eur J Gynaecol Oncol. 1994;15(1):50-8. Unique Identifier : AIDSLINE MED/94265795
Del Mistro A; Insacco E; Cinel A; Bonaldi L; Minucci D; Chieco-Bianchi L; Institute of Oncology, University of Padua, Italy.
The efficacy of treatment of HPV infections was evaluated in 14 HIV-1 seropositive women. Disease evolution was evaluated at follow-up examinations, and findings were compared to those in 14 historic HIV-negative women who had received similar treatment. HPV sequences were demonstrated by Southern blot in 13/14 HIV-po


Crystallization and biochemical characterisation of simian immunodeficiency virus proteinase mutant.
Biochem Soc Trans. 1994 Feb;22(1):55S. Unique Identifier : AIDSLINE MED/94266051
Corr BR; Wilderspin AF; Department of Crystallography, Birkbeck College, London.
Regional specificity of HTLV-I proviral integration in the human genome.
Gene. 1994 Jun 10;143(2):155-63. Unique Identifier : AIDSLINE MED/94266147
Zoubak S; Richardson JH; Rynditch A; Hollsberg P; Hafler DA; Boeri E; Lever AM; Bernardi G; Laboratoire de Genetique Moleculaire, Institut Jacques Monod,; Paris, France.
The location of HTLV-I (human T-cell leukemia virus type 1) proviral sequences in the genome of infected human cells was explored by hybridization of a viral probe with compositional fractions of host-cell DNAs. In the twelve cases examined, HTLV-I sequences were absent from the GC-poorest 40% of the host genome (name


Contraceptive methods and the transmission of HIV: implications for family planning.
Genitourin Med. 1994 Apr;70(2):110-7. Unique Identifier : AIDSLINE MED/94266271
Daly CC; Helling-Giese GE; Mati JK; Hunter DJ; Department of Epidemiology, Harvard School of Public Health,; Boston, MA.
Heterosexual transmission is the predominant mode of spread of the Human Immunodeficiency Virus (HIV) in most of the world. Whether the use of hormonal contraceptives, IUDs and spermicides is associated with an increased or decreased risk for HIV acquisition remains controversial. Several mechanisms whereby contracept


Infectious osteitis pubis in an HIV seropositive female.
Genitourin Med. 1994 Apr;70(2):127-9. Unique Identifier : AIDSLINE MED/94266275
Desmond N; Bignardi GE; Coker RJ; Grech P; Harris JR; Department of Genitourinary Medicine, St Mary's Hospital, London,; UK.
We report a case of infectious osteitis pubis following a first trimester abortion in a female seropositive for the human immunodeficiency virus (HIV). Joint aspiration yielded Pseudomonas aeruginosa and the patient was successfully treated with oral ciprofloxacin.


Disseminated histoplasmosis in patients with acquired immunodeficiency syndrome [clinical conference]
Genitourin Med. 1994 Apr;70(2):132-7. Unique Identifier : AIDSLINE MED/94266277
Miller RF; Lucas SB; Pinching AJ; Department of Medicine, University College London Medical School,; Middlesex Hospital, UK.
Sexually transmitted diseases in the history of Uganda.
Genitourin Med. 1994 Apr;70(2):138-45. Unique Identifier : AIDSLINE MED/94266278
Lyons M; Institute of Commonwealth Studies, University of London, UK.
First noticed in Uganda in 1863 by a European explorer, sexually transmitted diseases (STDs) were cited as a major cause of morbidity and mortality throughout this century. In 1908 the venereal diseases campaign was launched marking the real introduction of western medicine. By the


Periareolar breast abscess due to Pseudomonas aeruginosa in an HIV antibody positive male [letter] [published erratum appears in Genitourin Med 1994 Jun;70(3):230]
Genitourin Med. 1994 Apr;70(2):147-8. Unique Identifier : AIDSLINE MED/94266281
Higgins SP; Stedman YF; Bundred NJ; Woolley PD; Chandiok P; Chandler P [corrected to Chandiok P]
Lactic acidosis, non-Hodgkins lymphoma and the acquired immunodeficiency syndrome [letter]
Genitourin Med. 1994 Apr;70(2):148-9. Unique Identifier : AIDSLINE MED/94266282
Bergin C; Pilkington R; McCreary C; Mulcahy F; Crowley V
The natural history of HIV infection in women attending a sexually transmitted disease clinic in Dublin.
Genitourin Med. 1994 Apr;70(2):81-3. Unique Identifier : AIDSLINE MED/94266283
Mulcahy F; Kelly G; Tynan M; Genitourinary Medicine Clinic, St. James Hospital, Dublin.
OBJECTIVE--To determine the progression rates to AIDS in women in Dublin. SUBJECTS AND METHODS--109 HIV-1 seropositive women who presented to the Department of Genitourinary Medicine, St. James s Hospital, Dublin, were included in a retrospective analysis. Of these 101 (93%) were intravenous drug users (IVDUs), 7 were


Ceftriaxone in the treatment of chronic donovanosis in central Australia.
Genitourin Med. 1994 Apr;70(2):84-9. Unique Identifier : AIDSLINE MED/94266284
Merianos A; Gilles M; Chuah J; National Centre for Epidemiology and Population Health,; Australian National University, Canberra.
OBJECTIVES--To determine the effectiveness of intramuscular (IM) ceftriaxone sodium in the treatment of chronic donovanosis, and the acceptability to patients and staff of supervised outpatient treatment in rural clinics. METHODS--We collected demographic and sexual health data from participants using a standard quest


Chlamydia trachomatis in women: the more you look, the more you find.
Genitourin Med. 1994 Apr;70(2):97-100. Unique Identifier : AIDSLINE MED/94266287
Hay PE; Thomas BJ; Horner PJ; MacLeod E; Renton AM; Taylor-Robinson D; Division of Sexually Transmitted Diseases, Clinical Research; Centre, Harrow, Middlesex, UK.
OBJECTIVE--To determine the extent to which testing of multiple sites and samples is required to define whether a woman is Chlamydia trachomatis-positive. DESIGN--One-hundred and fifty women attending the Genitourinary Medicine clinic at St Mary s Hospital were enrolled; they had not received antichlamydial antibiotic


Anti-IL-2 receptor monoclonal antibody (anti-Tac) treatment of T-cell lymphoma.
Important Adv Oncol. 1994;:131-41. Unique Identifier : AIDSLINE MED/94266289
Waldmann TA; Metabolism Branch, National Cancer Institute, Bethesda, Maryland.
The abnormal and activated T cells in certain neoplasms of mononuclear cells, select autoimmune disorders, and organ allograft rejection express the IL-2R alpha subunit identified by the anti-Tac monoclonal antibody. In contrast, normal resting cells do not express this inducible receptor. Patients with ATL were treat


Human immunodeficiency virus-1 recombinant gp120 induces changes in protein kinase C isozymes--a preliminary report.
Int J Immunopharmacol. 1994 Mar;16(3):197-204. Unique Identifier : AIDSLINE MED/94266524
Gupta S; Aggarwal S; Kim C; Gollapudi S; Division of Basic and Clinical Immunology, University of; California, Irvine 92717.
Human immunodeficiency virus 1 (HIV-1) and its purified proteins activate target cell functions. Because protein kinase C (PKC) plays a crucial role in signal transduction and there is a molecular heterogeneity of PKC, we compared the effect of recombinant HIV-1 gp120 and phorbol ester (PMA) on PKC isozymes in monocyt


HIV-related ocular microangiopathic syndrome and color contrast sensitivity.
Invest Ophthalmol Vis Sci. 1994 Jun;35(7):3011-21. Unique Identifier : AIDSLINE MED/94266569
Geier SA; Hammel G; Bogner JR; Kronawitter U; Berninger T; Goebel FD; Augenklinik, Klinikum Innenstadt der; Ludwig-Maximilians-Universitat, Germany.
PURPOSE. Color vision deficits in patients with acquired immunodeficiency syndrome (AIDS) or human immunodeficiency virus (HIV) disease were reported, and a retinal pathogenic mechanism was proposed. The purpose of this study was to evaluate the association of color vision deficits with HIV-related retinal microangiop


Kinetic and modeling studies of subsites S4-S3' of Moloney murine leukemia virus protease.
J Biol Chem. 1994 Jun 17;269(24):16795-801. Unique Identifier : AIDSLINE MED/94266899
Menendez-Arias L; Weber IT; Soss J; Harrison RW; Gotte D; Oroszlan S; Laboratory of Molecular Virology and Carcinogenesis,; Institute-Frederick Cancer Research and Development Center,; Maryland 21702.
The substrate specificity of the Moloney murine leukemia virus protease (Mo-MuLV PR) was analyzed by using the oligopeptide substrate Val-Ser-Gln-Asn-Tyr decreases Pro-Ile-Val-Gln-NH2 and a series of analogs containing single amino acid substitutions in the P4-P3 positions. Mo-MuLV PR appears to act similarly to the


Melanoma: 1. Clinical characteristics.
Hosp Pract (Off Ed). 1994 Jun 15;29(6):37-40, 43-4, 47-50. Unique Identifier : AIDSLINE MED/94267027
Hoffman S; Yohn J; Robinson W; Norris D; University of Colorado, Denver.
The disease is perhaps the clearest instance of a cancer for which early treatment is crucial. Increasing knowledge of risk factors (including brief, intense sun exposure and sunburn damage early in life) aids the identification of persons at highest risk--one reason for physicians not to be pessimistic about the valu


Increased levels of soluble tumor necrosis factor receptor in patients with multiple sclerosis and HTLV-1-associated myelopathy.
J Neuroimmunol. 1994 Jun;52(1):33-40. Unique Identifier : AIDSLINE MED/94267058
Matsuda M; Tsukada N; Miyagi K; Yanagisawa N; Department of Medicine (Neurology), Shinshu University, School of; Medicine, Matsumoto, Japan.
Tumor necrosis factor-alpha (TNF-alpha) is a potent mediator produced by activated T lymphocytes and macrophages, which may play a role in the pathogenesis and development of multiple sclerosis (MS) and HTLV-1-associated myelopathy (HAM). The first step in the induction of many biological effects elicited by TNF-alpha


HIV transmission from surgeons and dentists to patients: can models predict the risk? [editorial; comment]
Infect Control Hosp Epidemiol. 1994 Mar;15(3):144-6. Unique Identifier : AIDSLINE MED/94267131
Mishu B; Schaffner W
Screening surgeons for HIV infection: assessment of a potential public health program [see comments]
Infect Control Hosp Epidemiol. 1994 Mar;15(3):147-55. Unique Identifier : AIDSLINE MED/94267132
Schulman KA; McDonald RC; Lynn LA; Frank I; Christakis NA; Schwartz JS; Clinical Economics Research Unit, Georgetown University Medical; Center, Washington, DC 20007.
OBJECTIVE: To develop a model to assess the impact of a program of testing surgeons for human immunodeficiency virus (HIV) on the risk of HIV acquisition by their patients. DESIGN: A Monte Carlo simulation model of physician-to-patient transmission of human immunodeficiency virus (HIV) infection using three different


HIV testing without consent determined unconstitutional in Alabama [news]
Infect Control Hosp Epidemiol. 1994 Mar;15(3):212. Unique Identifier : AIDSLINE MED/94267142
Pugliese G
Patient-to-patient transmission of hepatitis B in a dermatology practice [news]
Infect Control Hosp Epidemiol. 1994 Mar;15(3):212. Unique Identifier : AIDSLINE MED/94267143
Pugliese G
Use of infection control guidelines by workers in healthcare facilities to prevent occupational transmission of HBV and HIV: results from a national survey [see comments]
Infect Control Hosp Epidemiol. 1994 Apr;15(4 Pt 1):243-52. Unique Identifier : AIDSLINE MED/94267152
Hersey JC; Martin LS; Centers for Public Health Research and Evaluation of Battelle; Inc, Arlington, Virginia.
OBJECTIVE: Develop national estimates of compliance with infection control guidelines by workers in healthcare facilities to prevent occupational transmission of hepatitis B virus (HBV) and human immunodeficiency virus. DESIGN: A national survey of 3,094 workers in hospitals. SETTINGS: Uni


Female-to-female sexual transmission of HIV reported [news]
Infect Control Hosp Epidemiol. 1994 Apr;15(4 Pt 1):278-9. Unique Identifier : AIDSLINE MED/94267156
LFA-1-mediated antigen-independent T cell adhesion is regulated by CD4 and p56lck tyrosine kinase.
J Immunol. 1994 Jun 15;152(12):5670-9. Unique Identifier : AIDSLINE MED/94267172
Mazerolles F; Barbat C; Meloche S; Gratton S; Soula M; Fagard R; Fischer S; Hivroz C; Bernier J; Sekaly RP; et al; National Institute of Health and Medical Research (INSERM) U 132,; Necker Hospital for Sick Children, Paris, France.
We examined the role of CD4 and p56lck in the regulation of LFA-1-dependent T cell adhesion to B cells and to fibroblasts expressing ICAM-1 and HLA-DR by using various transfectant constructions. Although CD4 transfection in CD4low HUT78 T cell lines did not significantly modify their maximal binding to B cells and fi


TNF-beta produced by human T lymphotropic virus type I-infected cells influences the proliferation of human endothelial cells and fibroblasts.
J Immunol. 1994 Jun 15;152(12):5930-8. Unique Identifier : AIDSLINE MED/94267201
Yu F; Itoyama Y; Kira J; Fujihara K; Kobayashi T; Kitamoto T; Suzumura A; Yamamoto N; Nakajima Y; Goto I; Department of Neurology, Faculty of Medicine, Kyushu University,; Fukuoka, Japan.
Human T lymphotropic virus type I (HTLV-I) is linked to adult T cell leukemia as well as to HTLV-I-associated myelopathy/tropical spastic paraparesis. In this report, we studied the effects of HTLV-I-infected cell supernatants on HUVEC, fibroblasts, and glioma cells. The HTLV-I-infected cell supernatants (HUT102 and M


Overexpression of zinc-finger transcription factor Z-225/Egr-1 in synoviocytes from rheumatoid arthritis patients [published erratum appears in J Immunol 1994 Dec 1;153(11):5347]
J Immunol. 1994 Jun 15;152(12):5940-8. Unique Identifier : AIDSLINE MED/94267202
Aicher WK; Heer AH; Trabandt A; Bridges SL Jr; Schroeder HW Jr; Stransky G; Gay RE; Eibel H; Peter HH; Siebenlist U; et al; Clinical Research Group for Rheumatology (KFR), University of; Freiburg Medical School, Germany.
In rheumatoid arthritis (RA) the proliferation of synovial lining cells appears to be one of the initial pathologic changes that contributes to the destruction of articular joints. To understand the pathomechanisms involved in these functional changes, we analyzed the transcriptional regulation of the zinc-finger gene


Altered tissue distribution of viral replication and T cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of IFN-alpha/beta.
J Immunol. 1994 Jul 1;153(1):220-31. Unique Identifier : AIDSLINE MED/94267228
Sandberg K; Kemper P; Stalder A; Zhang J; Hobbs MV; Whitton JL; Campbell IL; Department of Neuropharmacology, Scripps Research Institute, La; Jolla, CA 92037.
IFN-alpha/beta have been shown to play a central role in the development of lymphocytic choriomeningitis and increasing attention has been focused on this group of cytokines as early regulatory factors directing T lymphocyte responses. In the present study, injection of antiserum to IFN-alpha/beta prevented the develo


CTL responses to the gag polyprotein encoded by the murine AIDS defective retrovirus are strain dependent.
J Immunol. 1994 Jul 1;153(1):436-41. Unique Identifier : AIDSLINE MED/94267252
Schwarz DA; Green WR; Department of Microbiology, Dartmouth Medical School, Lebanon, NH; 03756.
Murine AIDS (MAIDS) is induced by a mixture of retroviruses, of which a replication defective virus is the proximal agent of disease. This defective virus harbors a single intact gene that encodes an aberrant gag polyprotein. Certain mouse strains are genetically resistant to MAIDS, with several genes, including H-2Dd


Management of patients with HIV/AIDS: need for comprehensive care.
J Indian Med Assoc. 1994 Jan;92(1):11-4. Unique Identifier : AIDSLINE MED/94267275
Narain JP; Pattanayak S; WHO, South-East Asia Regional Office, New Delhi.
Women and AIDS.
J Indian Med Assoc. 1994 Jan;92(1):15-6, 38. Unique Identifier : AIDSLINE MED/94267276
Balaji LN; UNICEF, New Delhi.
AIDS and the gateway of the body.
J Indian Med Assoc. 1994 Jan;92(1):17-9. Unique Identifier : AIDSLINE MED/94267277
Bandyopadhyay P; Bhowal RN; Sikdar SN; Roy AK; Roy JG; Bandyopadhyay D; Pal NC; Chatterjee BD; Department of Dental Surgery, Medical College, Calcutta.
Campaigning against AIDS [editorial]
J Indian Med Assoc. 1994 Jan;92(1):2. Unique Identifier : AIDSLINE MED/94267278
Roy UK
Laboratory diagnosis of HIV infection.
J Indian Med Assoc. 1994 Jan;92(1):20-1. Unique Identifier : AIDSLINE MED/94267279
Shriniwas; Srivastava L; Lal S; National AIDS Control Organisation, Ministry of Health and Family; Welfare, New Delhi.
Blood safety and rational use of blood.
J Indian Med Assoc. 1994 Jan;92(1):22-3. Unique Identifier : AIDSLINE MED/94267280
Chawla SC; Lal S; Department of Preventive and Social Medicine, Lady Hardinge; Medical College and Associated Hospitals, New Delhi.
Opportunistic infection in AIDS.
J Indian Med Assoc. 1994 Jan;92(1):24-6. Unique Identifier : AIDSLINE MED/94267281
Sengupta D; Lal S; Shrinivas; National AIDS Control Organisation, Ministry of Health and Family; Welfare, New Delhi.
Vaccines for control of HIV infections.
J Indian Med Assoc. 1994 Jan;92(1):27-8. Unique Identifier : AIDSLINE MED/94267282
Sharma KB; WHO, New Delhi.
AIDS-case surveillance.
J Indian Med Assoc. 1994 Jan;92(1):29-30. Unique Identifier : AIDSLINE MED/94267283
Lal S; Khodakevich L; Sengupta D; National AIDS Control Organisation, New Delhi.
Current status of AIDS and HIV infection in India.
J Indian Med Assoc. 1994 Jan;92(1):3-4. Unique Identifier : AIDSLINE MED/94267284
Lal S; National AIDS Control Organisation, Ministry of Health and Family; Welfare, New Delhi.
HIV infection and health care worker.
J Indian Med Assoc. 1994 Jan;92(1):31-2. Unique Identifier : AIDSLINE MED/94267285
Munjal YP; IMA, New Delhi.
HIV infection control in health care settings.
J Indian Med Assoc. 1994 Jan;92(1):33-6. Unique Identifier : AIDSLINE MED/94267286
Shriniwas; Srivastva L; Sengupta D; Lal S; National AIDS Control Organisation, Ministry of Health and Family; Welfare, Government of India, New Delhi.
Safe sex.
J Indian Med Assoc. 1994 Jan;92(1):37-8. Unique Identifier : AIDSLINE MED/94267287
Mukherjee G; Ghosh TK; Department of Sexually Transmitted Disease, Calcutta National; Medical College.
Strategies for prevention and control of HIV infection/AIDS in the country.
J Indian Med Assoc. 1994 Jan;92(1):5-7. Unique Identifier : AIDSLINE MED/94267288
Dasgupta PR; National AIDS Control Organisation, Ministry of Health and Family; Welfare, New Delhi.
Sexually transmitted diseases and HIV infection: implications for control and prevention.
J Indian Med Assoc. 1994 Jan;92(1):8-10. Unique Identifier : AIDSLINE MED/94267289
van Dam CJ; WHO/GPA-India, New Delhi.
Deletion of a single N-linked glycosylation site from the transmembrane envelope protein of human immunodeficiency virus type 1 stops cleavage and transport of gp160 preventing env-mediated fusion.
J Gen Virol. 1994 Jun;75 ( Pt 6):1389-97. Unique Identifier : AIDSLINE MED/94267422
Dash B; McIntosh A; Barrett W; Daniels R; Division of Virology, National Institute for Medical Research,; Mill Hill, London, U.K.
The transmembrane envelope glycoprotein (gp41) of human immunodeficiency virus type 1 possesses four consensus sites (Asn-X-Ser/Thr) for the incorporation of N-linked sugars situated on the extracellular domain of the molecule. The purpose of this investigation was to determine the significance of each of these sites


Antibody-dependent cellular cytotoxicity and neutralization of human immunodeficiency virus type 1 by high affinity cross-linking of gp41 to human macrophage Fc IgG receptor using bispecific antibody.
J Gen Virol. 1994 Jun;75 ( Pt 6):1451-6. Unique Identifier : AIDSLINE MED/94267430
Mabondzo A; Boussin F; Raoul H; Le Naour R; Gras G; Vaslin B; Bartholeyns J; Romet-Lemonne JL; Dormont D; Laboratoire de Neuropathologie experimentale et Neurovirologie,; CRSSA, DSV/DPTE, Commissariat a l'Energie Atomique,; Fontenay-aux-Roses, France.
Human monocytes/macrophages, which express Fc receptors for IgG are involved in human immunodeficiency virus type 1 (HIV-1) infection and pathogenesis. These receptors are known to mediate numerous immunological functions including cell-mediated killing and possibly targeting of HIV to the lysophagosome monocyte-deriv


Single- and multi-hit kinetics of immunoglobulin G neutralization of human immunodeficiency virus type 1 by monoclonal antibodies.
J Gen Virol. 1994 Jun;75 ( Pt 6):1457-60. Unique Identifier : AIDSLINE MED/94267431
McLain L; Dimmock NJ; Department of Biological Sciences, University of Warwick,; Coventry, U.K.
A quantal assay, based on syncytium formation in the human T cell leukaemia-derived C8166 cell line, was used to determine the kinetics of human immuno-deficiency virus type 1 (HIV-1) strain IIIB neutralization. Three rat monoclonal antibodies (MAbs) were used, under physiological conditions of temperature and antibod


Basal and Tat-transactivated expression from the human immunodeficiency virus type 1 long terminal repeat in human placental trophoblast rules out promoter-enhancer activation as the partial block to viral replication.
J Gen Virol. 1994 Jun;75 ( Pt 6):1461-8. Unique Identifier : AIDSLINE GENBANK/S72421
Zachar V; Ebbesen P; Thomas RA; Zacharova V; Goustin AS; Center for Molecular Biology, Wayne State University, Detroit,; Michigan 48202.
We have analysed the capacity of the trophoblast-derived malignant cell lines BeWo, JAR and JEG-3, and primary cultures of highly purified trophoblast cells to support the basal and Tat-mediated trans-activation-enhanced transcriptional activity of two distinct human immunodeficiency virus type 1 (HIV-1) isolates. Kin


Inhibition of infectious human immunodeficiency virus type 1 particle formation by Gag protein-derived peptides.
J Gen Virol. 1994 Jun;75 ( Pt 6):1469-74. Unique Identifier : AIDSLINE MED/94267433
Niedrig M; Gelderblom HR; Pauli G; Marz J; Bickhard H; Wolf H; Modrow S; Behringwerke AG, Marburg, Germany.
Sequential overlapping Gag protein-derived oligopeptides of human immunodeficiency virus type 1 (HIV-1) 22 to 24 amino acids long, were synthesized and tested in vitro for antiviral activity. Two synthetic peptides, one derived from the matrix protein p17 (NPGLLETSEGCRQ, amino acids 47 to 59) and one located in the ca


Induction of neutralizing antibodies against human immunodeficiency virus type 1 using synthetic peptide constructs containing an immunodominant T-helper cell determinant from vpr.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):635-40. Unique Identifier : AIDSLINE MED/94267704
Sarobe P; Lasarte JJ; Golvano JJ; Prieto I; Gullon A; Soto MJ; Labarga P; Prieto J; Borras-Cuesta F; Departamento de Medicina Interna, Universidad de Navarra,; Pamplona, Spain.
Identification of immunodominant T-helper-cell determinants after natural infection is an important step in the design of immunogens for potential use in vaccination. Using cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals and a panel of peptides encompassing the sequence of the regulatory pr


Effects of HIV infection on VH3 (D12 idiotope) B cells in vivo.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):641-6. Unique Identifier : AIDSLINE MED/94267705
Berberian L; Shukla J; Jefferis R; Braun J; Department of Pathology and Laboratory Medicine, Jonsson; Comprehensive Cancer Center, University of California, Los; Angeles.
The abnormalities of B lymphocytes in human immunodeficiency virus (HIV) infection usually have been attributed to secondary consequences of disturbed immunoregulation. However, recent work has revealed avid binding of HIV gp120 to a conserved immunoglobulin motif unique to the VH3 gene family and the selective gp120-


Stimulation of HIV replication in mononuclear phagocytes by leukemia inhibitory factor.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):647-54. Unique Identifier : AIDSLINE MED/94267706
Broor S; Kusari AB; Zhang B; Seth P; Richman DD; Carson DA; Wachsman W; Lotz M; Department of Medicine, University of California, San Diego, La; Jolla.
This study examined the effects of leukemia inhibitory factor (LIF) on human immunodeficiency virus (HIV) replication in mononuclear phagocytes (MNP). LIF induced a dose-dependent increase in p24 antigen production in the chronically infected promonocytic cell line U1. The magnitude and time kinetics of the LIF effect


Construction and characterization of a potent HIV-2 Tat transdominant mutant protein.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):655-64. Unique Identifier : AIDSLINE MED/94267707
Echetebu CO; Rhim H; Herrmann CH; Rice AP; Division of Molecular Virology, Baylor College of Medicine,; Houston, Texas 77030.
The human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) Tat proteins Tat-1 and Tat-2 stimulate transcription of the viral long terminal repeat (LTR) sequences and are required for efficient viral replication. A class of mutant Tat proteins, termed transdominant mutants, has been described that possesses relat


Predicting progression of HIV disease: usefulness of acid-dissociated p24 antigen.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):676-80. Unique Identifier : AIDSLINE MED/94267709
Morand-Joubert L; Costagliola D; Bludau H; Petit JC; Lefrere JJ; Service de Bacterio-Virologie, Hopital Saint-Antoine, Paris,; France.
To ascertain whether immune complex dissociation (ICD) improves the value of p24 antigen as a prognostic marker for progression of HIV infection, 53 patients were followed over a 3-year period, including at least one visit per year. All had CD4+ counts at entry > 400/mm3; progressors (n = 18) were defined as having CD


The HIV wasting syndrome: a review.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):681-94. Unique Identifier : AIDSLINE MED/94267710
Coodley GO; Loveless MO; Merrill TM; Oregon Health Sciences University, Portland.
The HIV wasting syndrome and other HIV-associated weight loss is a major problem in HIV-infected patients. The available data strongly suggest that wasting is associated with decreased survival. It may also further impair immune function. A variety of etiologies probably contribute to this wasting, including hypermeta


Bleach use and HIV seroconversion among New York City injection drug users.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):700-4. Unique Identifier : AIDSLINE MED/94267712
Titus S; Marmor M; Des Jarlais D; Kim M; Wolfe H; Beatrice S; Department of Environmental Medicine, New York University School; of Medicine, NY 10010-2598.
We employed a nested case-control study design to evaluate the efficacy of bleach-cleaning of needles and syringes among injecting drug users (IDUs) as a means of preventing human immunodeficiency virus (HIV) infection. Sixteen HIV-seroconverters who responded to bleach use questions and who reported injecting with sh


Heterosexual transmission of human immunodeficiency virus type 1 from transfusion recipients to their sex partners.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):705-10. Unique Identifier : AIDSLINE MED/94267713
O'Brien TR; Busch MP; Donegan E; Ward JW; Wong L; Samson SM; Perkins HA; Altman R; Stoneburner RL; Holmberg SD; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, Georgia.
Using lookback procedures and other methods, we identified and then prospectively followed human immunodeficiency virus type 1 (HIV-1)-infected transfusion recipients and their sex partners to determine AIDS incidence and risks of heterosexual transmission of HIV-1. At enrollment, 7 of 32 (21.9%) female partners of ma


Risk factors for HIV-1 and HIV-2 infection in pregnant women in Dakar, Senegal.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):711-7. Unique Identifier : AIDSLINE MED/94267714
Abbott RC; NDour-Sarr A; Diouf A; NDoye T; Ba D; Tall N; MBaye N; Kebe F; Diadhiou F; Essex ME; et al; Department of Cancer Biology, Harvard School of Public Health,; Boston, Massachusetts 02115.
This study examines the prevalence and risk factors for Human Immunodeficiency Virus type 1 (HIV-1) and type 2 (HIV-2) infection in pregnant women in Dakar, Senegal . From April 1991 to January 1993, 9,518 pregnant women were interviewed and serologically tested for antibodies to H


Mycobacterium tuberculosis and its purified protein derivative activate expression of the human immunodeficiency virus.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):727-33. Unique Identifier : AIDSLINE MED/94267716
Lederman MM; Georges DL; Kusner DJ; Mudido P; Giam CZ; Toossi Z; Department of Medicine, Case Western Reserve University School of; Medicine, University Hospitals of Cleveland, Ohio 44106-4984.
To examine the effects of Mycobacterium tuberculosis on human immunodeficiency virus type 1 (HIV-1) expression, the monocytoid cell line U1 containing integrated provirus was incubated with the H37Ra strain of M. tuberculosis. This resulted in heightened expression of virus in supernatant that was partially inhibited


Polymorphism at the tumor necrosis factor-alpha locus and susceptibility to toxoplasmic encephalitis, ultraviolet B-induced immune impairment, and mouse AIDS [letter]
J Acquir Immune Defic Syndr. 1994 Jul;7(7):734-5. Unique Identifier : AIDSLINE MED/94267717
Vincek V; Kurimoto I; Streilein JW
Hiccups in people with AIDS [letter]
J Acquir Immune Defic Syndr. 1994 Jul;7(7):735. Unique Identifier : AIDSLINE MED/94267718
Albrecht H; Stellbrink HJ
HTLV-II infection is rare in patients with large granular lymphocyte leukemia [letter]
J Acquir Immune Defic Syndr. 1994 Jul;7(7):736-7. Unique Identifier : AIDSLINE MED/94267719
Heneine W; Chan WC; Lust JA; Sinha SD; Zaki SR; Khabbaz RF; Kaplan JE
Interpreting the power law relationship observed in studies of sexual behaviour [letter]
J Acquir Immune Defic Syndr. 1994 Jul;7(7):737-8. Unique Identifier : AIDSLINE MED/94267720
Brunham RC; Nagelkerke NJ; Plummer FA; Moses S
HIV prevalence and incidence among injection drug users in Los Angeles [letter]
J Acquir Immune Defic Syndr. 1994 Jul;7(7):738-9. Unique Identifier : AIDSLINE MED/94267721
Longshore D; Anglin MD
HIV, drug-use paraphernalia, and bleach.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):741-2. Unique Identifier : AIDSLINE MED/94267722
Haverkos HW; Jones TS; National Institute on Drug Abuse, Rockville, Maryland 20857.
Historical perspective on the use of bleach in HIV/AIDS prevention.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):743-6. Unique Identifier : AIDSLINE MED/94267724
Watters JK; Department of Family and Community Medicine, School of Medicine,; University of California, San Francisco 94143-1304.
In 1986, community outreach workers began distributing small bleach bottles to injection drug users (IDUs) in San Francisco as a simple means for them to reduce their risk of infection with HIV and other pathogens by quickly flushing their syringes with bleach. At inception, the intervention was based on four assumpti


In vitro activity of readily available household materials against HIV-1: is bleach enough?
J Acquir Immune Defic Syndr. 1994 Jul;7(7):747-53. Unique Identifier : AIDSLINE MED/94267725
Flynn N; Jain S; Keddie EM; Carlson JR; Jennings MB; Haverkos HW; Nassar N; Anderson R; Cohen S; Goldberg D; Department of Internal Medicine (Divisions of General Medicine; and Infectious Diseases), University of California Davis Medical; Center, Sacramento.
This report describes experiments assessing the effectiveness against HIV of potential disinfecting agents that are commonly available to IDU when they are sharing syringes. We exposed cell-free HIV, HIV-infected cells, and HIV-infected blood containing known quantities of HIV to household cleaning agents, alcohols, p


Preliminary laboratory studies of inactivation of HIV-1 in needles and syringes containing infected blood using undiluted household bleach.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):754-9. Unique Identifier : AIDSLINE MED/94267726
Shapshak P; McCoy CB; Shah SM; Page JB; Rivers JE; Weatherby NL; Chitwood DD; Mash DC; Comprehensive Drug Research Center, University of Miami, Florida.
To evaluate the effectiveness of bleach disinfection of injection equipment, we tested HIV-1 inactivation by household bleach in needles and syringes. We obtained blood from HIV-1 infected injecting drug users (IDUs), placed small aliquots in needles and syringes. Blood with and without anticoagulant was incubated at


Field effectiveness of needle disinfection among injecting drug users.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):760-6. Unique Identifier : AIDSLINE MED/94267727
Vlahov D; Astemborski J; Solomon L; Nelson KE; Department of Epidemiology, Johns Hopkins School of Hygiene and; Public Health, Baltimore, Maryland.
To examine the putative protective effect of disinfectant use on HIV seroconversion among injecting drug users, we conducted a nested case-control study of black heterosexuals comparing 34 HIV seroconverters with 154 persistent seronegatives matched on gender, cocaine injection (yes/no), date of study entry, and durat


Inadequate bleach contact times during syringe cleaning among injection drug users.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):767-72. Unique Identifier : AIDSLINE MED/94267728
Gleghorn AA; Doherty MC; Vlahov D; Celentano DD; Jones TS; Department of Health Policy and Management, Johns Hopkins; University School of Hygiene and Public Health, Baltimore,; Maryland.
Objectives were to measure syringe cleaning strategies used by injection drug users (IDUs) and to assess syringe contact with bleach during cleaning demonstrations. IDUs were interviewed about cleaning activities during their most recent injection episode; they demonstrated these activities on videotape. Coders review


Compliance to bleach disinfection protocols among injecting drug users in Miami.
J Acquir Immune Defic Syndr. 1994 Jul;7(7):773-6. Unique Identifier : AIDSLINE MED/94267729
McCoy CB; Rivers JE; McCoy HV; Shapshak P; Weatherby NL; Chitwood DD; Page JB; Inciardi JA; McBride DC; Comprehensive Drug Research Center, University of Miami, Florida.
Bleach cleansing of injection equipment has been recommended to reduce the risk of human immunodeficiency virus (HIV) transmission associated with the reuse of injection equipment by injecting drug users (IDUs). We evaluated the recall and performance of the most commonly recommended bleach cleansing procedure of two


Prodrugs of 2',3'-didehydro-3'-deoxythymidine (D4T): synthesis, antiviral activity, and rapid pharmacokinetic evaluation.
J Pharm Sci. 1994 Mar;83(3):339-43. Unique Identifier : AIDSLINE MED/94267748
Tortolani DR; Russell JW; Whiterock VJ; Hitchcock MJ; Ghazzouli I; Martin JC; Mansuri MM; Starrett JE Jr; Bristol-Myers Squibb Company, Pharmaceutical Research Institute,; Wallingford, CT 06492-7660.
A series of 5 -derivatives and modified pyrimidine analogues of 2 ,3 -didehydro-3 -deoxythymidine ( d4T , stavudine , 1) were synthesized to determine their potential as oral prodrugs of


Antimicrobial properties of alkaloids from Xanthorhiza simplicissima.
J Pharm Sci. 1994 Mar;83(3):404-6. Unique Identifier : AIDSLINE MED/94267760
Okunade AL; Hufford CD; Richardson MD; Peterson JR; Clark AM; Department of Pharmacognosy, School of Pharmacy, University of; Mississippi, University 38677.
The organic extract of the whole plant Xanthorhiza simplicissima was found to exhibit good activity against the AIDS-related opportunistic pathogens Candida albicans, Cryptococcus neoformans, and Mycobacterium intracellularae. Bioassay-directed fractionation of the extract led to the isolation of the known alkaloid be


LIP-model-based three-dimensional reconstruction and visualization of HIV-infected entire cells.
J Microsc. 1994 Apr;174 ( Pt 1):31-8. Unique Identifier : AIDSLINE MED/94267828
Gremillet P; Jourlin M; Pinoli JC; Misis Image, Saint-Etienne, France.
This paper presents a global solution from acquisition to visualization for the three-dimensional reconstruction of cell sections. Original techniques are proposed for the correct handling of geometrical section distortions, and a new interpretation based on the logarithmic image processing (LIP) model is applied in o


Evolution of chest radiographs in treated patients with pulmonary tuberculosis and HIV infection.
J Thorac Imaging. 1994 Spring;9(2):74-7. Unique Identifier : AIDSLINE MED/94267864
Small PM; Hopewell PC; Schecter GF; Chaisson RE; Goodman PC; Medical Service, San Francisco General Hospital Medical Center,; California.
A large number of patients with coexisting tuberculosis and HIV infection has been reported. The chest radiographic findings are well described and primarily consist of bilateral, medium-to-coarse reticulonodular opacities often associated with hilar and mediastinal adenopathy. The evolution of chest radiographic abno


Pulmonary manifestations of cryptococcosis in patients with AIDS: CT features.
J Thorac Imaging. 1994 Spring;9(2):78-84. Unique Identifier : AIDSLINE MED/94267865
Sider L; Westcott MA; Department of Diagnostic Radiology, Northwestern University; Medical School, Chicago, IL 60611.
The computed tomographic (CT) scans and chest radiographs of 10 patients with AIDS and proven pulmonary cryptococcal infections were reviewed. In seven patients (70%), CT demonstrated pulmonary opacities that ranged in appearance from a perihilar interstitial pattern to an area of dense alveolar consolidation. Corresp


Human immunodeficiency virus type 1 Tat upregulates interleukin-2 secretion in activated T cells.
J Virol. 1994 Jul;68(7):4177-85. Unique Identifier : AIDSLINE MED/94267876
Westendorp MO; Li-Weber M; Frank RW; Krammer PH; Division of Immunogenetics, Tumorimmunology Program, German; Cancer Research Center, Heidelberg.
Dysregulation of cytokines secreted by T cells may play an important role in the pathogenesis of AIDS. To investigate the effects of human immunodeficiency virus type 1 (HIV-1) Tat on interleukin-2 ( IL-2 ) expression, we used IL-2 promoter-chloramphenicol acetyltransfer


Characterization of replication-competent retroviruses from nonhuman primates with virus-induced T-cell lymphomas and observations regarding the mechanism of oncogenesis.
J Virol. 1994 Jul;68(7):4241-50. Unique Identifier : AIDSLINE GENBANK/S70177
Vanin EF; Kaloss M; Broscius C; Nienhuis AW; Genetic Therapy Inc., Gaithersburg, Maryland 20878.
Rapidly progressive T-cell lymphomas were observed in 3 of 10 rhesus monkeys several months after autologous transplantation of enriched bone marrow stem cells that had been transduced with a retroviral vector preparation containing replication-competent virus (R. E. Donahue, S. W. Kessler, D. Bodice, K. McDonagh, C.


The tumor suppressor protein p53 strongly alters human immunodeficiency virus type 1 replication.
J Virol. 1994 Jul;68(7):4302-13. Unique Identifier : AIDSLINE MED/94267889
Duan L; Ozaki I; Oakes JW; Taylor JP; Khalili K; Pomerantz RJ; Dorrance H. Hamilton Laboratories, Department of Medicine,; Jefferson Medical College, Thomas Jefferson University,; Philadelphia, Pennsylvania 19107.
The p53 tumor suppressor gene product, a sequence-specific DNA-binding protein, has been shown to act as a transcriptional activator and repressor both in vitro and in vivo. Consistent with its role in regulating transcription are recent observations that the N-terminal acidic domain of p53 binds directly to the TATA


Functional exchange of an oncoretrovirus and a lentivirus matrix protein.
J Virol. 1994 Jul;68(7):4442-9. Unique Identifier : AIDSLINE MED/94267905
Deminie CA; Emerman M; Program in Molecular Medicine, Fred Hutchinson Cancer Research; Center, Seattle, Washington 98104.
To map functional domains in the retroviral Gag protein we have constructed chimeric viruses where regions of the murine leukemia virus (MuLV) Gag protein have been replaced with analogous sequences from human immunodeficiency virus type 1 (HIV-1). Here we describe the chimeric virus MuLV(MAHIV) which contains the HIV


Serum neutralization of feline immunodeficiency virus is markedly dependent on passage history of the virus and host system.
J Virol. 1994 Jul;68(7):4572-9. Unique Identifier : AIDSLINE MED/94267920
Baldinotti F; Matteucci D; Mazzetti P; Giannelli C; Bandecchi P; Tozzini F; Bendinelli M; Department of Biomedicine, University of Pisa, Italy.
Sera from feline immunodeficiency virus (FIV)-infected cats exhibited extremely low levels of neutralizing antibodies against virus passaged a few times in vitro (low passage), when residual infectivity was assayed in the CD3+ CD4- CD8- MBM lymphoid cell line or mitogen-activated peripheral blood mononuclear cells. By


In vivo leukocyte tropism of bovine leukemia virus in sheep and cattle.
J Virol. 1994 Jul;68(7):4589-96. Unique Identifier : AIDSLINE MED/94267922
Schwartz I; Bensaid A; Polack B; Perrin B; Berthelemy M; Levy D; URA-Institut National de la Recherche Agronomique,; Immuno-Pathologie Cellulaire et Moleculaire, Ecole Nationale; Veterinaire, Maisons-Alfort, France.
Bovine leukemia virus (BLV), an oncovirus related to human T-cell leukemia virus type I, causes a B-cell lymphoproliferative syndrome in cattle, leading to an inversion of the T-cell/B-cell ratio and, more rarely, to a B-cell lymphosarcoma. Sheep are highly sensitive to BLV experimental infection and develop B-cell pa


Identification of human T-cell lymphotropic virus type I 21-base-pair repeat-specific and glial cell-specific DNA-protein complexes.
J Virol. 1994 Jul;68(7):4597-608. Unique Identifier : AIDSLINE MED/94267923
Tillmann M; Wessner R; Wigdahl B; Department of Microbiology and Immunology, College of Medicine,; Pennsylvania State University, Hershey 17033.
The human T-cell lymphotropic virus type I (HTLV-I)-encoded protein, Tax, is capable of trans-activating HTLV-I transcription by interacting with specific sequences in the HTLV-I long terminal repeat (LTR) which comprise an inducible enhancer containing three imperfect tandem repeats of a 21-bp sequence. There is no e


Postassembly cleavage of a retroviral glycoprotein cytoplasmic domain removes a necessary incorporation signal and activates fusion activity.
J Virol. 1994 Jul;68(7):4620-7. Unique Identifier : AIDSLINE MED/94267925
Brody BA; Rhee SS; Hunter E; Department of Microbiology, University of Alabama at Birmingham; 35294.
Viral protease-mediated cleavage within the cytoplasmic domain of the transmembrane (TM) glycoprotein of the type D retrovirus, Mason- Pfizer monkey virus, removes approximately 16 amino acids from the carboxy terminus of the protein. To determine the functional significanc


Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxin.
J Virol. 1994 Jul;68(7):4628-35. Unique Identifier : AIDSLINE MED/94267926
Gelbard HA; Nottet HS; Swindells S; Jett M; Dzenko KA; Genis P; White R; Wang L; Choi YB; Zhang D; et al; Department of Neurology, University of Rochester Medical Center,; Rochester, New York 14642.
The pathogenesis of central nervous system disease during human immunodeficiency virus type 1 (HIV-1) infection revolves around productive viral infection of brain macrophages and microglia. Neuronal losses in the cortex and subcortical gray matter accompany macrophage infection. The question of how viral infection of


Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences.
J Virol. 1994 Jul;68(7):4643-49. Unique Identifier : AIDSLINE MED/94267928
Power C; McArthur JC; Johnson RT; Griffin DE; Glass JD; Perryman S; Chesebro B; Department of Neurology, Johns Hopkins University, Baltimore,; Maryland 21287.
Human immunodeficiency virus (HIV) dementia is a common clinical syndrome of uncertain pathogenesis in patients with AIDS. In several animal models of retrovirus-induced brain disease, specific viral envelope sequences have been found to influence the occurrence of central nervous


Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome.
J Virol. 1994 Jul;68(7):4650-5. Unique Identifier : AIDSLINE MED/94267929
Koup RA; Safrit JT; Cao Y; Andrews CA; McLeod G; Borkowsky W; Farthing C; Ho DD; Aaron Diamond AIDS Research Center, New York University School of; Medicine, New York 10016.
Virologic and immunologic studies were performed on five patients presenting with primary human immunodeficiency virus type 1 (HIV-1) infection. CD8+ cytotoxic T lymphocyte (CTL) precursors specific for cells expressing antigens of HIV-1 Gag, Pol, and Env were detected at or within 3 weeks of presentation in four of t


Changes in the cytopathic effects of human immunodeficiency virus type 1 associated with a single amino acid alteration in the ectodomain of the gp41 transmembrane glycoprotein.
J Virol. 1994 Jul;68(7):4662-8. Unique Identifier : AIDSLINE MED/94267931
Cao J; Vasir B; Sodroski JG; Dana-Farber Cancer Institute, Department of Pathology, Harvard; Medical School, Boston, Massachusetts 02115.
A human immunodeficiency virus type 1 mutant with a single amino acid change (designated 596 W/M) in the ectodomain of the gp41 transmembrane envelope glycoprotein replicated in T-cell lines and in CD4-positive peripheral blood mononuclear cells identically to the wild-type virus. However, the cytopathic effects assoc


Adoptive transfer of polyclonal and cloned cytolytic T lymphocytes (CTL) specific for mouse AIDS-associated tumors is effective in preserving CTL responses: a measure of protection against LP-BM5 retrovirus-induced immunodeficiency.
J Virol. 1994 Jul;68(7):4679-84. Unique Identifier : AIDSLINE MED/94267934
Green WR; Green KA; Crassi KM; Department of Microbiology, Dartmouth Medical School, Lebanon,; New Hampshire 03756.
Cytolytic T lymphocytes (CTL) can be raised against C57BL/6 B-cell lymphomas from mice with LP-BM5 murine leukemia virus-induced AIDS (MAIDS). Adoptive transfer of polyclonal anti-MAIDS tumor CTL or two CTL clones specific for the B6-1710 MAIDS lymphoma caused preservation of major histocompatibility complex-restricte


Stimulation of virus production and induction of self-syncytium formation in human T-cell leukemia virus type I- and type II-infected T cells by 12-O-tetradecanoylphorbol-13-acetate.
J Virol. 1994 Jul;68(7):4695-9. Unique Identifier : AIDSLINE MED/94267937
Wolfson M; Lev M; Avinoah I; Malik Z; Lochelt M; Flugel RM; Dombrovski A; Aboud M; Department of Microbiology and Immunology, Faculty of Health; Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.
Treatment of human T-cell leukemia virus type I (HTLV-I)- and HTLV-II-infected T-cell lines with 12-O-tetradecanoylphorbol-13-acetate (TPA) stimulated virus release. However, this stimulation was mainly detected at 42 to 48 h of treatment, whereas later virus release declined rapidly. During the first 48 h, TPA had no


Prototypical HTLV-I/II infection is rare in LGL leukemia.
Leuk Res. 1994 Jun;18(6):423-9. Unique Identifier : AIDSLINE MED/94268111
Loughran TP Jr; Sherman MP; Ruscetti FW; Frey S; Coyle T; Montagna RA; Jones B; Starkebaum G; Poiesz BJ; Veterans Affairs Medical Center, Syracuse, NY 13210.
The etiology of LGL leukemia is not known; however, we recently detected HTLV-II in a patient with LGL leukemia. In this study, we found that sera from 6 of 28 patients with LGL leukemia were positive for HTLV-I/II using a whole virus ELISA; moreover, the ELISA-negative sera were near the positive cut-off value. There


Lymph, lymphomania, lymphotrophy, and HIV lymphocytopathy: an historical perspective.
Lymphology. 1994 Mar;27(1):21-40. Unique Identifier : AIDSLINE MED/94268119
Shields JW; Department of Medicine and Hematology, Santa Barbara Medical; Foundation Clinic, California.
From 1578-1628, Fabricius and his pupils, Asellius and Harvey, sequentially laid the foundations for the modern sciences of comparative anatomy, lymphology and circulation, as well as a state of lympho-philia or -mania which persists to the present time. Lymphomania persists because there remains a fundamental controv


Environmental induction of tumor phenotype in a putative Kaposi sarcoma progenitor cell.
Lymphology. 1994 Mar;27(1):45-8. Unique Identifier : AIDSLINE MED/94268121
Mallery SR; Lantry LE; Hegtvedt A; Lazo A; Titterington LC; Hout BL; Brierley GP; Stephens RE; College of Dentistry, Department of Pathology, Ohio State; University, Columbus.
Many features of AIDS-related Kaposi sarcoma (AIDS-KS), e.g., multifocal lesional presentation at sites perfused by the microvasculature, suggest that AIDS-KS is initially a hyperplasia that subsequently progresses to a neoplasia. We propose that the unique AIDS environment, which contains high levels of circulating f


[Cardiac tamponade and Kaposi's sarcoma]
Med Clin (Barc). 1994 Apr 9;102(13):495-7. Unique Identifier : AIDSLINE MED/94268174
Just M; Raventos A; Romeu J; Larrousse E; Santos J; Ojanguren I; Servicio de Medicina Interna, Hospital Germans Trias i Pujol.; Badalona, Universidad Autonoma, Barcelona.
The case of a 31 year-old intravenous drug addict female patient with infection by the human immunodeficiency virus who had recurrent cardiac tamponade and who was diagnosed by pericardic biopsy as Kaposi s sarcoma is reported. The patient demonstrated involvement by cutaneous, mucosal, lymph node and probably pleurop


[Pentoxifylline in patients with AIDS and oral aphthous ulcers (letter; comment)]
Med Clin (Barc). 1994 Apr 9;102(13):519. Unique Identifier : AIDSLINE MED/94268183
Santos J; Marquez M; Rivero A; Salgado F
[Disseminated infection caused by Mycobacterium avium complex and stereotaxic cerebral biopsy. Diagnosis and treatment in a patient with AIDS (letter)]
Med Clin (Barc). 1994 Apr 16;102(14):556. Unique Identifier : AIDSLINE MED/94268193
Garcia-Ruiz F; Benito-Leon J; Palenque E; Mon-Mon C
[Primary prevention of toxoplasmosis in patients with HIV infection (editorial)]
Med Clin (Barc). 1994 Apr 30;102(16):621-3. Unique Identifier : AIDSLINE MED/94268205
Pena JM; Vazquez JJ
HIV western blot test [letter]
Med J Aust. 1994 Jun 20;160(12):807-8. Unique Identifier : AIDSLINE MED/94268397
Turner VF
More on the declining age at HIV infection [letter]
N Engl J Med. 1994 Jul 14;331(2):134. Unique Identifier : AIDSLINE MED/94268524
Hugues-Davies TH
Images in clinical medicine. Wallerian degeneration of the pyramidal tract on magnetic resonance imaging.
N Engl J Med. 1994 Jul 14;331(2):88. Unique Identifier : AIDSLINE MED/94268530
Dol JA; Louwerse ES; Academic Medical Center, Amsterdam, The Netherlands.
Diseases of the retina.
N Engl J Med. 1994 Jul 14;331(2):95-106. Unique Identifier : AIDSLINE MED/94268532
D'Amico DJ; Department of Ophthalmology, Harvard Medical School, Boston, MA.
US puts large-scale AIDS vaccine trials on ice as 'premature' [news]
Nature. 1994 Jun 23;369(6482):593. Unique Identifier : AIDSLINE MED/94268533
Macilwain C
Long PCR.
Nature. 1994 Jun 23;369(6482):684-5. Unique Identifier : AIDSLINE GENBANK/M22639
Cheng S; Chang SY; Gravitt P; Respess R; Department of Human Genetics, Roche Molecular Systems, Inc.,; Alameda, California 94501.
Waiting lists for coronary artery surgery: can they be better organised? [see comments]
N Z Med J. 1994 Jun 8;107(979):211-5. Unique Identifier : AIDSLINE MED/94268765
Agnew TM; Whitlock RM; Neutze JM; Kerr AR; Green Lane Hospital, Auckland.
AIM. To determine whether a numerical ranking system can provide an equitable basis for prioritising patients awaiting coronary artery bypass grafting. METHODS. A review of the current coronary surgery waiting list was undertaken using a newly developed scoring system. The factors included in the score were age, sympt


Identification of human immunodeficiency virus type 2 in a New Zealand resident.
N Z Med J. 1994 Jun 8;107(979):217-9. Unique Identifier : AIDSLINE MED/94268767
Shroeder BA; Bridle M; Croxson MC; Franklin R; Department of Virology and Immunology, Auckland Hospital.
AIMS. To determine the human immunodeficiency virus (HIV) types infecting a West African immigrant to New Zealand . To develop an HIV type 2 specific polymerase chain reaction (PCR). METHODS. The HIV antibody status of the patient was determined using both HIV-1 and dual HIV-1 a


Aspects of central venous access catheter usage in patients with malignancy.
N Z Med J. 1994 Jun 8;107(979):224-6. Unique Identifier : AIDSLINE MED/94268770
Hardman D; Englund R; Hanel K; Department of Vascular Surgery, St George's Hospital, Sydney,; NSW, Australia.
AIMS. A review of 5 years experience with central venous access catheters (CVAC) to examine the results of catheter placement technique (open or percutaneous) on subsequent CVAC performance. In addition the catheter function and utilisation of both Hickman type and Access Port type of CVAC were reviewed to assess the


Effect of abasic linker substitution on triplex formation, Sp1 binding, and specificity in an oligonucleotide targeted to the human Ha-ras promoter.
Nucleic Acids Res. 1994 May 25;22(10):1909-16. Unique Identifier : AIDSLINE MED/94268916
Mayfield C; Miller D; Department of Medicine, University of Alabama at Birmingham.
A region of the human Ha-ras promoter (-8 to -28) which contains two of the three Sp1 binding sites essential for transcriptional activity forms a sequence specific oligonucleotide-directed pur*pur:pyr triple helix. The relative binding of oligonucleotides containing different substitutions, including an abasic propan


[Latent virus infections of cells in the immune system]
Postepy Hig Med Dosw. 1993;47(6):403-13. Unique Identifier : AIDSLINE MED/94268932
Blach-Olszewska Z; Instytut Immunologii i Terapii Doswiadczalnej im. L. Hirszfelda; PAN, Wroclawiu.
The article concerns the latent infections of cells of immune system caused by herpesviruses and retroviruses. Molecular basis of latency maintained by Epstein-Barr virus in B lymphocytes as well as by human immunodeficiency virus in TCD4 lymphocytes is described. The switch between latency and replication of the viru


[Biology and therapy of hairy cell leukemia]
Postepy Hig Med Dosw. 1993;47(6):437-61. Unique Identifier : AIDSLINE MED/94268934
Robak T; II Klinika Chorob Wewnetrznych AM, Lodzi.
In the paper recent advances in etiology and pathogenesis of hairy cell leukaemia (HCL) are reviewed. Role of human T-cell leukaemia virus II (HTLV-II) and Epstein-Barr virus as well as benzene and other environmental factors in the etiology of this leukaemia is presented. The new achievements in diagnosis including e


[New perspective antisense strategies--regulation of protein biosynthesis]
Postepy Biochem. 1994;40(1):18-22. Unique Identifier : AIDSLINE MED/94268939
Bohun E; Twardowski T; Instytut Chemii Bioorganicznej PAN, Poznan.
[Microsporidioses]
Presse Med. 1994 Feb 19;23(7):332-8. Unique Identifier : AIDSLINE MED/94269008
Beauvais B; Sarfati C; Lariviere M; Derouin F; Laboratoire de Parasitologie-Mycologie, Hopital Saint-Louis,; Paris.
Microsporidia are worldwide ubiquitous intracellular protozoan parasites infecting most major groups of the animal kingdom. In humans, microsporidiosis has recently emerged as a significant cause of morbidity in immunocompromised patients, and particularly in patients


[Cacosmia during treatment with zidovudine (letter)]
Presse Med. 1994 Feb 26;23(8):393. Unique Identifier : AIDSLINE MED/94269024
Caron F; Marie I; Gueit I; Borsa-Lebas F; Humbert G
Association of severe haemophilia A with osteoporosis: a densitometric and biochemical study.
Q J Med. 1994 Mar;87(3):181-6. Unique Identifier : AIDSLINE MED/94269255
Gallacher SJ; Deighan C; Wallace AM; Cowan RA; Fraser WD; Fenner JA; Lowe GD; Boyle IT; University Department of Medicine, Glasgow Royal Infirmary, UK.
Following a femoral neck fracture and vertebral compression fractures in two patients with severe haemophilia A, bone density and turnover were measured in 19 males with severe haemophilia A (all HIV negative, 18/19 hepatitis C antibody positive) and in 19 age/sex matched controls. Bone density at the lumbar spine (L2


[Neuroradiology of infective diseases in the immunocompromised host]
Radiol Med (Torino). 1994 May;87(5 Suppl 2):13-25. Unique Identifier : AIDSLINE MED/94269383
Cecchini A; Pricca P; Poggi P; Servizio di Radiodiagnostica, Policlinico San Matteo, IRCCS,; Pavia.
Just like the lung, the brain and the spinal cord are target organs for opportunistic infections and tumors in immunocompromised patients. HIV infections and AIDS-related conditions represent the most common cause of immunodeficiency: other causes are hemoproliferative disorders and organ transplantation, but especial


[Nuclear imaging in AIDS-related neurologic diseases]
Radiol Med (Torino). 1994 May;87(5 Suppl 2):26-33. Unique Identifier : AIDSLINE MED/94269384
Scopinaro G; Pigorini F; Servizio di Medicina Nucleare, Ospedali Galliera, Genova.
A total of 356 patients with HIV-1 infection at different immunological and neurologic stages were included in this study. Patients with CNS opportunistic signs were excluded. All patients underwent SPET with HMPAO-99mTc; 166 patients were submitted to brain CT and 48 to MRI no later than 30 days after SPET examinatio


[Lung infections in acquired immunodeficiency. Clinico-radiologic correlations]
Radiol Med (Torino). 1994 May;87(5 Suppl 2):34-51. Unique Identifier : AIDSLINE MED/94269385
Cecconi L; Busi Rizzi E; Mazzuoli G; Schinina V; Servizio di Radiologia, Ospedale L. Spallanzani, USL RM 10, Roma.
Over the last decade the number of subjects with acquired immunodeficiencies has markedly increased; this phenomenon depends on both the large number of patients receiving organ transplants or antiblastic therapy and the spread of infections caused by the HIV virus. In 70-90% of these patients primary diseases include


[Abdominal manifestations in immunocompromised patients]
Radiol Med (Torino). 1994 May;87(5 Suppl 2):52-61. Unique Identifier : AIDSLINE MED/94269387
Cornalba GP; Dore R; Colombo E; Servizio di Radiologia, Ospedale L. Sacco, Milano.
Abdominal infections or tumors in the immunocompromised host are both common in AIDS but uncommon in transplant recipients. The role of diagnostic imaging modalities differs in the patients with specific symptoms such as dysphagia, diarrhea, malabsorption and jaundice and in the patients with aspecific clinical findin


[Diagnostic imaging in immunosuppressed subjects: malignant tumors]
Radiol Med (Torino). 1994 May;87(5 Suppl 2):62-72. Unique Identifier : AIDSLINE MED/94269388
Morassut S; Servizio di Radiologia, Centro di Riferimento Oncologico di; Aviano, Pordenone.
Each state of immunodeficiency is complicated by an increased incidence of certain types of cancer. The risk factors in the development of malignancies increase in a time-dependent relationship with the age of the defect in cell-mediated immunity and some tumors will develop at fairly distinct time intervals during im


[AIDS in childhood]
Radiol Med (Torino). 1994 May;87(5 Suppl 2):73-6. Unique Identifier : AIDSLINE MED/94269389
Bellini F; Plebani A; Barbaccia P; Bolzoni S; Grumieri GP; Pavesi MA; Servizio di Radiologia, Universita di Milano.
HIV infection in infants is transmitted through the placenta. Antibodies reduce and annul in nearly 18 months: HIV + subjects older than 18 months are considered as infected and divided into two classes--i.e., P1: infected and P2: AIDS. The most interesting clinical and diagnostic imaging findings are reported relativ


[Interventional modalities in immunosuppressed patients]
Radiol Med (Torino). 1994 May;87(5 Suppl 2):77-89. Unique Identifier : AIDSLINE MED/94269390
Dore R; Cornalba GP; Di Maggio EM; Di Giulio G; Preda L; Istituto di Radiologia, Policlinico San Matteo, IRCCS, Pavia.
In immunocompromised patients interventional modalities have diagnostic and/or therapeutic purposes--in both cases they are justified on the basis of the frequently aspecific clinical and instrumental findings and because of the clinical need to carry out the most specific treatment as soon as possible. The authors st


[AIDS: organizational and medico-legal problems]
Radiol Med (Torino). 1994 May;87(5 Suppl 2):90-4. Unique Identifier : AIDSLINE MED/94269391
Papagni L; Minoli L; Servizio di Radiologia, Ospedale San Luca, Milano.
The medical imaging of AIDS patients may turn out a major challenge for hospital organization, since the specific problems related to this syndrome in terms of abnormal changes and increased diagnostic burden are to be matched with infection control procedures. Data obtained from 12 radiology departments in Lombardia


Chemoprophylaxis for tuberculosis [letter; comment]
Respir Med. 1993 Jul;87(5):398-9. Unique Identifier : AIDSLINE MED/94269425
Stanford JL; Stanford CA; Rook GA; Carswell JW; Grange JM; Pozniak A
Pneumothorax in patients with AIDS [letter; comment]
Respir Med. 1993 Jul;87(5):400-1. Unique Identifier : AIDSLINE MED/94269428
Munro NC; Wood A; Scott D; Turner G; Hamilton P
[The contribution of PCR to the diagnosis and follow-up of HIV infection]
Schweiz Rundsch Med Prax. 1994 May 17;83(20):615-8. Unique Identifier : AIDSLINE MED/94269497
Burgisser P; Division d'immunologie et allergie, Centre hospitalier; universitaire vaudois, Lausanne.
PCR permits diagnosis of HIV infection by the detection of proviral DNA sequences in circulating lymphocytes. It is the method of choice for diagnosing infection in children born to seropositive mothers. PCR is also a helpful tool when the result of serodiagnosis remains indeterminate of atypical. It may allow the dia


[Range of neuromuscular involvement in 47 patients infected with the human immunodeficiency virus]
Schweiz Med Wochenschr. 1994 May 14;124(19):791-800. Unique Identifier : AIDSLINE MED/94269574
Ghika-Schmid F; Kuntzer T; Chave JP; Miklossy J; Regli F; Service de neurologie, Centre hospitalier universitaire vaudois,; Lausanne.
Over a 30 month period, 47 out of 749 patients infected with the human immunodeficiency virus had various neuromuscular symptoms. Based on clinical and electrophysiological data, 47% had distal symmetric polyneuropathy, 11% chronic inflammatory demyelinating polyneuropathy (CIDP), 8.5% toxic neuropathy related to 2-3-


AIDS vaccines. Will media reports KO upcoming real-life trials? [news]
Science. 1994 Jun 17;264(5166):1660. Unique Identifier : AIDSLINE MED/94269622
Cohen J
The impact of condom prices on sales in social marketing programs.
Stud Fam Plann. 1994 Jan-Feb;25(1):52-8. Unique Identifier : AIDSLINE MED/94269790
Harvey PD; DKT International, Washington, DC 20036.
The issue of pricing contraceptives in family planning programs is becoming more and more important. What is the relationship between consumer prices and demand, and how can we strike the correct balance between the two? This report examines the correlation between consumer prices for condoms, expressed as a percentag


Signal transduction defect in the acquired immunodeficiency syndrome and AIDS-related complex.
Thymus. 1993 Sep;22(2):83-90. Unique Identifier : AIDSLINE MED/94269795
Gupta S; Division of Basic and Clinical Immunology, University of; California, Irvine.
Peripheral blood mononuclear cells from patients with the acquired immunodeficiency syndrome (AIDS), AIDS-related complex (ARC), and heterosexual controls were stimulated with anti-CD3 monoclonal antibody, phorbol myristate acetate (PMA), or both and 3H thymidine incorporation and


[A method for transporting blood samples for the determination of antibodies to HIV infection]
Vrach Delo. 1993 Apr;(4):102-3. Unique Identifier : AIDSLINE MED/94269842
Bogomolov FI; Tomashuk VS; Sheleva VM
More than 80,000 blood samples are annually transported to the Lutsk diagnostic center for assessment of antibodies to HIV. A polystyrol container for 50 vials is used for transportation of the blood samples for these purpose. The advantages of this way of transportation are discussed.


[Initial clinical results with heat-treated homologous bone transplants]
Z Orthop Ihre Grenzgeb. 1994 Mar-Apr;132(2):102-11. Unique Identifier : AIDSLINE MED/94270001
Kuhne JH; Refior HJ; Jansson V; DeToma G; Liepold KP; Verpoorten U; Orthopadischen Klinik und Poliklinik,; Ludwig-Maximilians-Universitat Munchen.
Several ways for HIV inactivation in bone allografts are being discussed. These methods must be efficient, but they must not compromise biologic properties of the allografts. According to animal studies, moderate heat treatment of bone allografts in a 65 degrees C waterbath has no adverse effects on osseointegration.


[An original experience through the creation of a new functional rehabilitation center for Vietnamese lepers]
Acta Leprol. 1994;9(1):35-43. Unique Identifier : AIDSLINE MED/94270092
Vu DL; Chabaud B; Nguyen KK; Nguyen VT; Hoang TQ; Centre de dermato-venerologie d'Ho Chi Minh-Ville, Vietnam.
Since 1990, the creation of a Rehabilitation Center for Vietnamese leprosy patients under the aegis of Oeuvres Hospitalieres Francaises de l Ordre de Malte is the result of emphasized collaboration between governmental and non-governmental organizations, and between medical and paramedical specialists. This humanitari


Esophageal dysphagia.
Acta Otorhinolaryngol Belg. 1994;48(2):171-90. Unique Identifier : AIDSLINE MED/94270145
Kahrilas PJ; Ergun GA; Department of Medicine, Northwestern University, Chicago,; Illinois.
This paper is a review of esophageal anatomy, physiology and pathophysiology. The diagnosis and therapy of benign and malignant esophageal strictures are discussed including the specifics of esophageal dilation and tumor ablation procedures. The diagnosis and therapy of esophagitis in the immunocompromised (HIV, chemo


Use of semiquantitative human immunodeficiency virus type 1 culture to guide therapy in a premature infant.
Am J Clin Pathol. 1994 Jun;101(6):753-5. Unique Identifier : AIDSLINE MED/94270352
Toltzis P; Marx CM; Balfour HH Jr; Jackson JB; Division of Infectious Diseases, Case Western Reserve University; School of Medicine, Cleveland, OH 44106.
Semiquantitative cultures for human immunodeficiency virus type 1 were used to initiate and guide therapy in an asymptomatic, heavily infected premature infant. The cultures were performed on fivefold serial dilutions of peripheral blood mononuclear cells, and viral growth was detected by the appearance of p24 antigen


High frequency of Epstein-Barr virus latent membrane protein-1 expression in acquired immunodeficiency syndrome-related Ki-1 (CD30)-positive anaplastic large-cell lymphomas. Italian Cooperative Group on AIDS and Tumors.
Am J Clin Pathol. 1994 Jun;101(6):768-72. Unique Identifier : AIDSLINE MED/94270355
Carbone A; Gloghini A; Volpe R; Boiocchi M; Tirelli U; Division of Pathology, Istituto Nazionale di Ricovero e Cura a; Carattere Scientifico, Aviano Italy.
Immunohistochemical detection of Epstein-Barr virus (EBV)-encoded latent membrane protein-1 (LMP-1) was used to identify EBV-associated Ki-1-positive anaplastic large-cell (ALC) lymphomas occurring in 11 patients with and 29 patients without human immunodeficiency virus (HIV) infection. In addition, 18 representative


Immunophenotypic and genotypic analysis of acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas. Correlation with histologic features in 36 cases. French Study Group of Pathology for HIV-Associated Tumors.
Am J Clin Pathol. 1994 Jun;101(6):773-82. Unique Identifier : AIDSLINE MED/94270356
Raphael MM; Audouin J; Lamine M; Delecluse HJ; Vuillaume M; Lenoir GM; Gisselbrecht C; Lennert K; Diebold J; Haematology Department, Pitie-Salpetriere Hospital, Paris,; France.
High-grade B-cell-type non-Hodgkin s lymphomas are observed in 5% to 8% of patients positive for the human immunodeficiency virus. Nearly all cases belong to one of the three major histologic types: centroblastic or large noncleaved cell, immunoblastic and Burkitt s lymphoma, or small noncleaved cell. Some cases that


Risk factors for the transition from noninjection to injection drug use and accompanying AIDS risk behavior in a cohort of drug users.
Am J Epidemiol. 1994 Jun 15;139(12):1153-63. Unique Identifier : AIDSLINE MED/94270362
van Ameijden EJ; van den Hoek JA; Hartgers C; Coutinho RA; Department of Public Health and Environment, Amsterdam, The; Netherlands.
Although injection drug users have been shown to reduce high-risk injection behaviors in response to the epidemic of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS), the total elimination of risk behaviors has not been achieved. A more fundamental preventive measure may be to


The application of saliva, sweat and tear fluid for diagnostic purposes.
Ann Biol Clin (Paris). 1993;51(10-11):903-10. Unique Identifier : AIDSLINE MED/94270601
Haeckel R; Hanecke P; Institute for Laboratory Medicine Zentralkrankenhaus, Bremen,; Germany.
Despite anatomical and biochemical similarities, salivary, sweat and lacrimal glandulas differ in their physiological functions. Salivary and tear fluid are required for the proper function of the epithelial layer from which they are secreted. The physiological function of sweat is the elimination of excess heat. The


[Microsporida microsporidiosis]
Ann Biol Clin (Paris). 1994;52(1):37-44. Unique Identifier : AIDSLINE MED/94270606
Deluol AM; Cenac J; Laboratoire de microbiologie, hopital Rothschild, Paris, France.
Microsporidia were infrequent in man until 1985. A new species, Enterocytozoon bieneusi, responsible for diarrhea, was described in AIDS patients in 1985. Little is known about the parasite; its diagnosis is difficult, and its incidence certainly underestimated. This work summarizes current knowledge on microsporidia


[Acral erythema occurring after didanosine (Videx) therapy]
Ann Dermatol Venereol. 1993;120(11):837-40. Unique Identifier : AIDSLINE MED/94270672
Pedailles S; Launay V; Surbled M; Sentias C; Bazin A; Service de Dermatologie, Hopital Pasteur, Cherbourg.
[Ultrasonographic data of the solid organs of the abdomen in stage IV human immunodeficiency virus infection. A prospective study of 101 cases in central Africa]
Ann Gastroenterol Hepatol (Paris). 1994 Mar-Apr;30(2):43-52. Unique Identifier : AIDSLINE MED/94270742
Aubry P; Reynaud JP; Nbonyingingo C; Ndabaneze E; Mucikere E; Hopital d'Instruction des Armees Robert Picque,; Bordeaux-Armees.
A systematic abdominal study of the solid organs of the abdomen (liver, spleen, pancreas, kidneys) carried out in one hundred patients from Central Africa suffering from full blown AIDS revealed disseminated hyperechoic liver in 37 cases and hypoechoic nodules of the spleen in 10 cases. The combination with abdominal


Indurated plaques and persistent ulcers in an HIV-1 seropositive man. Silicone granulomas (reaction to silicone injection).
Arch Dermatol. 1994 Jun;130(6):785-6, 788-9. Unique Identifier : AIDSLINE MED/94270845
Baselga E; Pujol R; Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Human immunodeficiency virus infection in long-distance truck drivers in east Africa.
Arch Intern Med. 1994 Jun 27;154(12):1391-6. Unique Identifier : AIDSLINE MED/94270886
Bwayo J; Plummer F; Omari M; Mutere A; Moses S; Ndinya-Achola J; Velentgas P; Kreiss J; Department of Medical Microbiology, University of Nairobi, Kenya.
BACKGROUND: A cross-sectional survey was performed to determine the seroprevalence and correlates of human immunodeficiency virus (HIV) infection among long-distance truck drivers in Kenya . METHODS: Truck drivers along the Mombasa-Nairobi highway were enrolled at a roadside research


Generation of multiple drug resistance by sequential in vitro passage of the human immunodeficiency virus type 1.
Arch Virol. 1994;136(1-2):111-22. Unique Identifier : AIDSLINE MED/94270977
Gao Q; Gu Z; Salomon H; Nagai K; Parniak MA; Wainberg MA; Lady Davis Institute, Jewish General Hospital, Montreal, Quebec,; Canada.
We have sequentially passaged both laboratory and clinical isolates of the human immunodeficiency virus type 1 (HIV-1) in MT-4 cells in the presence of increasing concentrations of different drugs to derive viral variants that are multiply resistant to various combinations of


HIV-1 infection of in vitro cultured human monocytes: early events and influence of anti HIV-1 antibodies.
Arch Virol. 1994;136(1-2):35-52. Unique Identifier : AIDSLINE MED/94270989
Arendrup M; Olofsson S; Nielsen JO; Hansen JE; Department of Infectious Diseases, University of Copenhagen,; Hvidovre Hospital, Denmark.
To characterize the role of the humoral immune response on HIV-1 infection of monocytes and macrophages (M phi s) we examined the susceptibility of in vitro cultured monocyte/M phi s to various HIV-1 isolates and the influence of heterologous and particularly autologous anti HIV-1 sera on this infection. Depending on


[Tropical spastic paraparesis in the tropics and Brazil. A historical analysis]
Arq Neuropsiquiatr. 1994 Mar;52(1):106-9. Unique Identifier : AIDSLINE MED/94271000
de Castro-Costa CM; Carton H; Goubau P; de Figueiredo EG; Giffoni SD; Servico de Neurologia, Hospital Universitario Walter Cantidio,; Universidade Federal do Ceara (UFCE), Fortaleza, Brasil.
The tropical spastic paraparesis (TSP) is a chronic myelopathy, predominant in the tropics, recently known to be of retroviral origin (HTLV-I). This paper aims at delineating the clinico-etiological evolution of this entity. The historical analysis of it showed that the TSP has had, along decades, many different denom


Genetic tests to reveal TAT homodimer formation and select TAT homodimer inhibitor.
Biochem Biophys Res Commun. 1994 Jun 15;201(2):701-8. Unique Identifier : AIDSLINE MED/94271221
Battaglia PA; Longo F; Ciotta C; Del Grosso MF; Ambrosini E; Gigliani F; Dipartimento di Biopatologia Umana, Universita La Sapienza,; Policlinico Umberto I, Roma, Italy.
The HIV Tat protein is essential for productive infection and is a potent activator of viral gene expression. By constructing a genetic fusion between the amino-terminal DNA-binding domain of the lambda repressor (as a reporter for dimerization) and Tat, we show that Tat forms dimers in vivo. By deletion analysis and


Interferon-gamma induces resistance in primary monocytes against human immunodeficiency virus type-1 infection.
Biochem Biophys Res Commun. 1994 Jun 15;201(2):756-61. Unique Identifier : AIDSLINE MED/94271229
Dhawan S; Heredia A; Lal RB; Wahl LM; Epstein JS; Hewlett IK; Laboratory of Molecular Virology, Food and Drug Administration; (HFM-310), Rockville, MD 20852.
Treatment of monocytes with interferon-gamma 1 day before, or at the time of infection with human immunodeficiency virus type-1 (HIV-1) induced complete resistance in monocytes against HIV-1 infection. There was no evidence of viral RNA, proviral DNA, p24 antigen, or reverse transcriptase activity through 2 weeks afte


Birth outcomes following zidovudine therapy in pregnant women [published erratum appears in MMWR Morb Mortal Wkly Rep 1994 Jun 24;43(24):450]
MMWR Morb Mortal Wkly Rep. 1994 Jun 10;43(22):409, 415-6. Unique Identifier : AIDSLINE MED/94254774
Approximately 100,000 childbearing-aged women in the United States are infected with human immunodeficiency virus (HIV), and an estimated 7000 infants are born to HIV-positive mothers each year. In the United States, the rate of perinatal transmission of HIV among mothers who do not re


The effects of 4 Mrad of gamma irradiation on the initial mechanical properties of bone-patellar tendon-bone grafts.
Arthroscopy. 1994 Apr;10(2):188-97. Unique Identifier : AIDSLINE MED/94271372
Rasmussen TJ; Feder SM; Butler DL; Noyes FR; Orthopedic and Sports Medicine Consultants, Shawnee Mission,; Kansas.
Pairs of frozen human patellar tendon-bone (PTB) ligament allografts were exposed to either 0 or 4 Mrad of gamma irradiation sterilization, the latter value based on recent reports suggesting higher dosage levels for adequate sterilization against the human immunodeficiency virus. All specimens were subjected to three


[Emergent pathologies: Rhodococcus equi infection in the acquired immunodeficiency syndrome (editorial)]
Ann Ital Med Int. 1994 Jan-Mar;9(1):10-1. Unique Identifier : AIDSLINE MED/94271659
Fiaccadori F
Rhodococcus equi is an intracellular facultative, gram-positive, partially acid-fast, cocco-bacillary microorganism of increasing importance as a pathogen in severely immunocompromised HIV-positive patients. Rhodococcus equi may cause invasive pulmonary infection, bacteremia and disseminated infection. Rhodococcus equ


The syndrome of idiopathic CD4+ lymphocytopenia.
Ann Ital Med Int. 1994 Jan-Mar;9(1):22-6. Unique Identifier : AIDSLINE MED/94271662
Famularo G; Giacomelli R; De Simone C; Tonietti G; Cattedra di Clinica Medica, Universita degli Studi de L'Aquila.
The syndrome of idiopathic CD4+ lymphocytopenia has recently been recognized and referred to as the persistent depletion of peripheral blood CD4+ T lymphocytes below 300 cells per cubic millimeter or less than 20% of total lymphocytes in the absence of either HIV infection or other known causes of immunodeficiency. Th


A comprehensive central register of more than 700 HIV/AIDS initiatives [news]
Nurs Stand. 1994 Apr 6-12;8(28):12. Unique Identifier : AIDSLINE MED/94271682
New drug for exposure to HIV goes on trial [news]
Nurs Stand. 1994 Apr 6-12;8(28):15. Unique Identifier : AIDSLINE MED/94271683
AIDS focus. The second decade in South East Asia.
Nurs Stand. 1994 Apr 6-12;8(28):42-3. Unique Identifier : AIDSLINE MED/94271690
Weller B
AIDS focus. Developing staff support.
Nurs Stand. 1994 Apr 6-12;8(28):44-6. Unique Identifier : AIDSLINE MED/94271691
Jamieson S
AIDS focus. Training for the front line.
Nurs Stand. 1994 Apr 6-12;8(28):47-8. Unique Identifier : AIDSLINE MED/94271692
Scott M
Aromatherapy. Working with clients who are HIV positive [letter]
Nurs Stand. 1994 Apr 20-26;8(30):83. Unique Identifier : AIDSLINE MED/94271703
Toomer S
Determination of 2'-deoxy-3'-thiacytidine (3TC) in human urine by liquid chromatography: direct injection with column switching.
J Pharm Biomed Anal. 1994 Feb;12(2):255-64. Unique Identifier : AIDSLINE MED/94271851
Morris DM; Selinger K; Department of Clinical Pharmacology, Glaxo Inc. Research; Institute, Research Triangle Park, NC 27709.
3TC (GR109714X) is a cytidine dideoxynucleoside analogue which has been shown to have in vitro activity against a variety of strains of HIV-1 and is currently being investigated in clinical trials as a treatment for HIV infection. An HPLC method for t


[Bowenoid papulosis. Review of 4 cases in a health center]
Aten Primaria. 1994 Apr 30;13(7):367-71. Unique Identifier : AIDSLINE MED/94271904
Manzano de Arostegui JA; Borbujo Martinez J; Juez Juez AA; Calderon Ubeda J; Manget Velasco S; Casado Jimenez M; Centro de Salud V Centenario, San Sebastian de los Reyes,; Madrid.
OBJECTIVE. To check the clinical, histological, evolutionary and therapeutic characteristics of Bowen s Disease. DESIGN: A descriptive study of a crossover type. SETTING. Primary Care and a Dermatology clinic at a Health Centre. PATIENTS. There were 4 adult males, aged between 25 and 31, with pigmented papulosis lesio


[Attitudes of primary health personnel towards HIV infected patients (letter)]
Aten Primaria. 1994 Apr 30;13(7):399-400. Unique Identifier : AIDSLINE MED/94271912
Lozano Padilla C; Laynez Bretones F; Diez Garcia F
Necrolytic migratory erythema without glucagonoma in a heroin-dependent patient.
Dermatology. 1994;189(1):72-4. Unique Identifier : AIDSLINE MED/94272129
Bencini PL; Vigo GP; Caputo R; Istituto di Clinica Dermatologica I, Universita di Milano, IRCCS; Ospedale Maggiore, Italia.
We described a case of necrolytic migratory erythema without glucagonoma in a 33-year-old man. The patient had been heroin-dependent, HIV negative since the age of 23. He had no medical history of note and all the investigations revealed normal parameters. This is the first case of necrolytic migratory erythema withou


The risk of varicella-zoster infections in different patient populations: a critical review.
Transfus Med Rev. 1994 Apr;8(2):96-116. Unique Identifier : AIDSLINE MED/94272200
Rusthoven JJ; Department of Medical Oncology, Ontario Cancer Treatment and; Research Foundation, Hamilton Regional Cancer Centre, Canada.
Primary mesenteric tumor of adult T-cell leukemia/lymphoma: report of a case.
Surg Today. 1994;24(3):263-7. Unique Identifier : AIDSLINE MED/94272213
Nishimura Y; Takenaka H; Yoshidome K; Iwase K; Oshima S; Tanaka T; Department of Surgery, Kinan General Hospital, Wakayama, Japan.
A rare case of primary mesenteric tumor of adult T-cell leukemia/lymphoma (ATLL) is reported. A 64-year-old man was admitted to our hospital after the diagnosis of a palpable ileocecal tumor. Although the serologic test for human T-cell lymphotrophic virus type I (HTLV-I) antibody was positive, neither ATLL cells in t


[Tests for an early detection of pulmonary cryptococcosis by sputum culture]
Bull Soc Pathol Exot. 1994;87(1):41-4. Unique Identifier : AIDSLINE MED/94272248
Mukamurangwa P; Bogaerts J; Taelman H; Batungwanayo J; Kagame A; van de Perre P; Swinne D; Laboratoire de Mycologie, Institut de Medecine tropicale,; Anvers, Belgique.
Cryptococcosis is a serious opportunistic infection occurring in acquired immunodeficiency syndrome (AIDS) patients. As the number of infected patients with the human immunodeficiency virus (HIV) in Central Africa and especially in Rwanda increases, the prevalence of cryptococcosis


FDI policy statement on the human immunodeficiency virus (HIV), the acquired immune deficiency syndrome (AIDS), and dentistry. Revised August 1992. Federation Dentaire Internationale.
Dent World. 1993 Mar-Apr;2(2):11-8. Unique Identifier : AIDSLINE MED/94272254
Age related effects of lectins on GAG metabolism in cultured embryonic fibroblasts.
Cell Mol Biol (Noisy-le-grand). 1994 Mar;40(2):183-92. Unique Identifier : AIDSLINE MED/94272313
Becchetti E; Locci P; Marinucci L; Lilli C; Pezzetti F; Carinci P; Dipartimento di Medicina Sperimentale, Universita di Perugia,; Italy.
Lectins (WGA, SBA or PNA) were administered to 7 and 14 days chick embryo fibroblasts to evaluate their ability to influence GAG cellular and extracellular accumulation. HA and sulphated GAG were differently affected by lectins. WGA addition to culture medium enhanced HA and sulphated GAG in the two examined compartme


Sculpting proteins interactively: continual energy minimization embedded in a graphical modeling system.
Protein Sci. 1994 Feb;3(2):198-210. Unique Identifier : AIDSLINE MED/94272322
Surles MC; Richardson JS; Richardson DC; Brooks FP Jr; San Diego Supercomputer Center, California 92186-9784.
We describe a new paradigm for modeling proteins in interactive computer graphics systems--continual maintenance of a physically valid representation, combined with direct user control and visualization. This is achieved by a fast algorithm for energy minimization, capable of real-time performance on all atoms of a sm


A structural role for arginine in proteins: multiple hydrogen bonds to backbone carbonyl oxygens.
Protein Sci. 1994 Apr;3(4):541-8. Unique Identifier : AIDSLINE MED/94272337
Borders CL Jr; Broadwater JA; Bekeny PA; Salmon JE; Lee AS; Eldridge AM; Pett VB; Department of Chemistry, College of Wooster, Ohio 44691.
We propose that arginine side chains often play a previously unappreciated general structural role in the maintenance of tertiary structure in proteins, wherein the positively charged guanidinium group forms multiple hydrogen bonds to backbone carbonyl oxygens. Using as a criterion for a structural arginine one that f


Pulmonary disease associated with the human immunodeficiency virus in Kigali, Rwanda. A fiberoptic bronchoscopic study of 111 cases of undetermined etiology.
Am J Respir Crit Care Med. 1994 Jun;149(6):1591-6. Unique Identifier : AIDSLINE MED/94272737
Batungwanayo J; Taelman H; Lucas S; Bogaerts J; Alard D; Kagame A; Blanche P; Clerinx J; van de Perre P; Allen S; Department of Internal Medicine, Centre Hospitalier de Kigali,; Rwanda.
All human immunodeficiency virus type 1 (HIV-1) infected adult patients referred to the Division of Pulmonary Diseases of the Centre Hospitalier de Kigali, Rwanda for evaluation of a pulmonary disease of undetermined etiology (PDUE) were investigated by fiberoptic bronchoscopy usin


Nontuberculous mycobacteria. An underappreciated cause of geriatric lung disease [see comments]
Am J Respir Crit Care Med. 1994 Jun;149(6):1654-8. Unique Identifier : AIDSLINE MED/94272747
Kennedy TP; Weber DJ; Division of Respiratory and Critical Care Medicine, Duke; University Medical Center, Durham, North Carolina.
Nontuberculous mycobacteria (NTM) infection is a frequent opportunistic infection in patients infected with the human immunodeficiency virus. However, NTM infection may also occur in nonimmunocompromised hosts. In order to determine the spectrum of mycobacterial infection in the nonacademic setting, we analyzed the de


UCSF AIDS research RNs protest layoffs.
Calif Nurse. 1994 Apr;90(4):7. Unique Identifier : AIDSLINE MED/94272998
AIDS and dentistry [letter; comment]
J Can Dent Assoc. 1994 May;60(5):362. Unique Identifier : AIDSLINE MED/94273000
Hardie J
MR imaging evaluation of bone marrow signal change in post-irradiation patients with nasopharyngeal carcinoma.
Chung Hua I Hsueh Tsa Chih (Taipei). 1994 Apr;53(4):208-13. Unique Identifier : AIDSLINE MED/94273019
Shen WC; Chen CC; Chiang CM; Liu CK; Lee SK; Lin JC; Jan JS; Department of Radiology, Taichung Veterans General Hospital,; Taiwan, R.O.C.
BACKGROUND. The normal distribution of red and yellow marrow can be altered by therapeutic irradiation, which causes a well-documented sequence of bone marrow changes. This study measured the T1 signal intensity of the clivus and cervical vertebral bodies of NPC patients who had received a complete course of radiation


The spectrum of chronic lymphoproliferative disorders in Chinese people. An analysis of 64 cases.
Cancer. 1994 Jul 1;74(1):174-81. Unique Identifier : AIDSLINE MED/94273084
Kwong YL; Wong KF; Chan LC; Liang RH; Chan JK; Wei D; Chiu EK; Chan CH; Todd D; Chan TK; University Department of Medicine, Queen Mary Hospital, Hong; Kong.
BACKGROUND. Chronic lymphoproliferative disorders are considered rare in Oriental patients and are thought to constitute only 2% of all leukemias in these patients, compared to 20-30% in Western patients. We conducted a retrospective analysis of Chinese patients with chronic lymphoproliferative disorders to define the


Studies of human immunodeficiency virus type 1 (HIV-1) protease inhibitors. III. Structure-activity relationship of HIV-1 protease inhibitors containing cyclohexylalanylalanine hydroxyethylene dipeptide isostere.
Chem Pharm Bull (Tokyo). 1994 Mar;42(3):534-40. Unique Identifier : AIDSLINE MED/94273216
Sakurai M; Higashida S; Sugano M; Handa H; Komai T; Yagi R; Nishigaki T; Yabe Y; Biological Research Laboratories, Sankyo Co., Ltd., Tokyo, Japan.
Systematic replacement of the P4-P2 subsites of substrate-based human immunodeficiency virus type 1 protease (HIV-1 PR) inhibitors containing cyclohexylalanylalanine hydroxyethylene dipeptide isostere (Cha-psi [H.E.]-Ala) at positions corresponding to the scissile sites of substrates was carried out. The structure-act


Synthesis and hypnotic and anti-human immunodeficiency virus-1 activities of N3-substituted 2'-deoxy-2'-fluorouridines.
Chem Pharm Bull (Tokyo). 1994 Mar;42(3):595-8. Unique Identifier : AIDSLINE MED/94273225
Sato Y; Utsumi K; Maruyama T; Kimura T; Yamamoto I; Richman DD; Department of Pharmaceutical Sciences, Tokushima Bunri; University, Japan.
Reaction of 9-[3,5-di-O-(tetrahydropyran-2-yl)-beta-D-arabinofuranosyl]uracil (2) with diethylaminosulfur trifluoride in the presence of pyridine afforded 2 -deoxy-2 -fluororiboside 3a, from which 2 -deoxy-2 -fluorocytidine (4b) has been synthesized in good yield. Compound 3a was deprotected and subsequently treated w


Structural and conformational studies of [Ile7] and [Leu7]surfactins from Bacillus subtilis natto.
Chem Pharm Bull (Tokyo). 1994 Mar;42(3):604-7. Unique Identifier : AIDSLINE MED/94273227
Itokawa H; Miyashita T; Morita H; Takeya K; Hirano T; Homma M; Oka K; Tokyo College of Pharmacy, Japan.
A novel [Ile7]surfactin (1), which showed anti-human immunodeficiency virus activity, has been isolated from Bacillus subtilis natto. Structural and conformational analysis of the peptide backbone of [Ile7]surfactin was conducted by a combination of various two-dimensional (2D) nuclear magnetic resonance (NMR), circul


Antibody-dependent enhancement of HIV-1 infection in human term syncytiotrophoblast cells cultured in vitro.
Clin Exp Immunol. 1994 Jun;96(3):389-94. Unique Identifier : AIDSLINE MED/94273337
Toth FD; Mosborg-Petersen P; Kiss J; Aboagye-Mathiesen G; Zdravkovic M; Hager H; Aranyosi J; Lampe L; Ebbesen P; Danish Cancer Society, Department of Virus and Cancer, Aarhus.
We examined if Fc receptor-mediated antibody-dependent enhancement (FcR-ADE) or complement-mediated antibody-dependent enhancement (C -ADE) of virus infection can contribute to increasing replication of HIV-1 in human syncytiotrophoblast (ST) cells. Here we report that both FcR-ADE and C -ADE may result in enhanced vi


Diffuse thallium lung uptake in Pneumocystis carinii pneumonia [see comments]
Clin Nucl Med. 1994 Apr;19(4):287-91. Unique Identifier : AIDSLINE MED/94273396
Abdel-Dayem HM; Di Fabrizio L; Kowalsky W; Aras T; Sadik A; Kempf J; Habbab MN; Pescatore F; Bag R; Department of Nuclear Medicine, St. Vincent's Hospital & Medical; Center, New York, NY 10011.
Five patients with AIDS with Pneumocystis carinii pneumonia (PCP) showed diffuse bilateral lung uptake on sequential thallium and gallium scans. This creates a problem in the sequential use of these tests for the differentiation of Kaposi s sarcoma from acute inflammatory or other malignant diseases. In Kaposi s sarco


Periportal fibrosis secondary to transfusion siderosis in two patients with acquired immune deficiency syndrome (AIDS) treated with zidovudine--a confusing ultrasound appearance.
Clin Radiol. 1993 Aug;48(2):125-6. Unique Identifier : AIDSLINE MED/94273431
Wetton CW; Goldin R; Crofton ME; Department of Radiology, St Mary's Hospital, London.
We present the confusing sonographic features of periportal fibrosis in two AIDS patients who had zidovudine-induced transfusion siderosis of the liver. To our knowledge this has not been previously reported in the literature. The clinical, pathological and sonographic features are described.


Lymphocyte colony formation by aleukemic sheep infected with bovine leukemia virus.
Comp Immunol Microbiol Infect Dis. 1994 Feb;17(1):1-13. Unique Identifier : AIDSLINE MED/94273471
Johnson R; Kaneene JB; Lloyd JW; Department of Clinical Sciences, College of Veterinary Medicine,; E. Lansing, MI 48824-1316.
The objective of this study was to investigate the effects of bovine leukemia virus (BLV) infection in sheep. A prospective study of the serologic, hematologic, and histologic changes of sheep infected with BLV was conducted. Antibodies to BLV were detectable in the sheep 3 weeks after exposure to blood from an infect


Cell-mediated and humoral immunity in sheep exposed to bovine immunodeficiency-like virus.
Comp Immunol Microbiol Infect Dis. 1994 Feb;17(1):29-39. Unique Identifier : AIDSLINE MED/94273473
Smith HE; Jacobs RM; Mallard B; Department of Pathology, University of Guelph, Ontario, Canada.
Six sheep were transfused intraperitoneally with whole blood from two sheep chronically infected with the bovine immunodeficiency-like virus (BIV). Five sheep were transfused intraperitoneally (i.p.) with normal ovine whole blood and served as controls. Five of six BIV-inoculated sheep seroconverted; four were transie


Nephropathy in HIV-transgenic mice.
Contrib Nephrol. 1994;107:194-204. Unique Identifier : AIDSLINE MED/94273509
Kopp JB; Ray PE; Adler SH; Bruggeman LA; Mangurian CV; Owens JW; Eckhaus MA; Bryant JL; Klotman PE; Laboratory of Developmental Biology, National Institute of Dental; Research, National Institutes of Health, Bethesda, Md.
Integrative agnosia following progressive multifocal leukoencephalopathy.
Cortex. 1994 Mar;30(1):145-58. Unique Identifier : AIDSLINE MED/94273526
Butter CM; Trobe JD; Department of Psychology, University of Michigan.
A 43 year-old man with presumed progressive multifocal leukoencephalopathy developed difficulty recognizing objects and faces in the presence of adequate visual acuity and visual fields. His copying and matching of line drawings was intact, suggesting that his agnosia was associative. However, he had difficulty percei


A multi-institutional study of interobserver agreement in the evaluation of dementia with rCBF/SPET technetium-99m exametazime (HMPAO).
Eur J Nucl Med. 1994 Apr;21(4):306-13. Unique Identifier : AIDSLINE MED/94273721
Hellman RS; Tikofsky RS; Van Heertum R; Coade G; Carretta R; Hoffmann RG; Department of Radiology, Medical College of Wisconsin, Milwaukee.
Although specific patterns of technetium-99m exametazime [99mTc-hexamethylpropylene amine oxime (HMPAO)] brain single-photon emission tomography (SPET) uptake have been described for patients with dementia , no multi-institutional study has evaluated interobserver agreement. Interob


Subtyping of Mycobacterium avium complex (MAC) isolates by thin-layer chromatography--distribution of subtypes from patients with AIDS compared with clinically non-significant isolates.
Epidemiol Infect. 1994 Jun;112(3):543-9. Unique Identifier : AIDSLINE MED/94273794
Chew W; Sorrell TC; Gilbert GL; Department of Clinical Microbiology, Westmead Hospital, New South; Wales, Australia.
Thin-layer chromatography (TLC) was compared with seroagglutination for subtyping of Mycobacterium avium complex (MAC) bacteria. Seventy-five significant MAC isolates from patients with AIDS were typed by both methods and 36 isolates, judged to be clinically non-significant, were examined by TLC only. Overall, 75% of


Eosinophilia in patients with HIV-1 infection [letter]
Eur J Haematol. 1994 Apr;52(4):246-7. Unique Identifier : AIDSLINE MED/94273813
van der Graaf W; Borleffs JC
Local antibodies against Pneumocystis carinii in bronchoalveolar lavage fluid.
Eur Respir J. 1994 Apr;7(4):679-85. Unique Identifier : AIDSLINE MED/94273825
Laursen AL; Jensen BN; Andersen PL; Dept of Medicine and Infectious Diseases, Marselisborg Hospital,; University of Aarhus, Denmark.
Pneumocystis carinii pneumonia (PCP) is a frequent cause of pneumonia among human immunodeficiency virus (HIV)-infected patients. Little is known, however, about the role played by humoral immunity to control the infection. This study was undertaken to elucidate the role played by local antibodies. Bronchoalveolar lav


Successful treatment of AIDS-related pulmonary Kaposi's sarcoma with liposomal daunorubicin.
Eur Respir J. 1994 Apr;7(4):824-5. Unique Identifier : AIDSLINE MED/94273846
Schurmann D; Dormann A; Grunewald T; Ruf B; 2nd Dept of Internal Medicine (Dept for Infectious Diseases),; Rudolf Virchow University Hospital, Freie Universitat Berlin,; Germany.
We report a 35 year old male, human immunodeficiency virus (HIV)-infected patient with acquired immune deficiency syndrome (AIDS), who presented with rapidly progressive pulmonary Kaposi s sarcoma. The tumour regressed with treatment with liposomal daunorubicin and remained in partial remission until the patient died


AHCPR announces two new guidelines. Clinical practice guidelines on the evaluation and management of early HIV infection.
Fla Nurse. 1994 Apr;42(4):11. Unique Identifier : AIDSLINE MED/94273904
A community benefit plan.
Fla Nurse. 1994 Apr;42(4):8. Unique Identifier : AIDSLINE MED/94273906
Edwards BB
Antiviral drugs: present status and future prospects.
Int J Biochem. 1994 May;26(5):621-30. Unique Identifier : AIDSLINE MED/94273928
van der Sijs IH; Wiltink EH; Academic Medical Centre, Department of Pharmacy, Amsterdam, The; Netherlands.
1. There is a limited number of antiviral drugs available for therapy. Many investigations and new analytical techniques have unraveled the development and progression of a viral infection. Nowadays there is a good understanding of the multiplication cycle of viruses, including the human immunodeficiency virus. 2. In


Cell surface down-modulation of CD4 after infection by HIV-1.
FASEB J. 1994 Jun;8(9):593-600. Unique Identifier : AIDSLINE MED/94273974
Geleziunas R; Bour S; Wainberg MA; McGill AIDS Centre, Lady Davis Institute, Jewish General; Hospital, Montreal, Quebec, Canada.
Entry of HIV-1 into host cells is generally mediated by the cell surface CD4 receptor after specific interaction with the viral envelope glycoprotein gp120. Infection by HIV-1 commonly leads to the disappearance of CD4 from the plasma membrane, a phenomenon referred to as receptor down-modulation. This, in turn, rende


HIV infection and necrotizing stomatitis.
Gen Dent. 1994 Jan-Feb;42(1):66-8. Unique Identifier : AIDSLINE MED/94273996
Muzyka BC; Glick M; Department of Oral Medicine, Infectious Disease Center, Temple; University School of Dentistry, Philadelphia.
[Ultrastructural study of placentas from HIV seropositive women]
Ginecol Obstet Mex. 1994 May;62:136-42. Unique Identifier : AIDSLINE MED/94274108
Villegas Castrejon H; Carrillo Farga J; Paredes Y; Barron A; Karchmer S; Depto. de Microscopia Electronica, Fac. de Medicina, UNAM.,; Mexico, D.F.
Eleven placentas from seropositive women for HIV, were analyzed. In three cases the material came from first trimester abortions and the other eight from term pregnancies. In five cases retroviruses were identified, similar to HIV in the placental tissue. It was demonstrated for the first time the internalization of a


Polymorphisms in the 3' untranslated region of the I kappa B/MAD-3 (NFKBI) gene located on chromosome 14.
Hum Genet. 1994 Jun;93(6):694-6. Unique Identifier : AIDSLINE MED/94274208
Glavac D; Ravnik-Glavac M; O'Brien SJ; Dean M; Biological Carcinogenesis and Development Program, Program; Resources, Inc./DynCorp, Frederick, MD 21702-1201.
The NF-kappa B transcription factor regulates the expression of a number of genes, including immune function and growth control loci, and several viruses. For example, the long terminal repeat of the human immunodeficiency virus contains NF-kappa B binding sites. NF-kappa B activity in the nucleus is regulated by a ce


Why our patients don't trust us about infection control.
Ill Dent J. 1993 Sep-Oct;62(5):335-6. Unique Identifier : AIDSLINE MED/94274225
Neiburger EJ
Transfusion associated HIV infection in patients with haematologic disorders in southern India.
Indian J Med Res. 1994 Feb;99:57-60. Unique Identifier : AIDSLINE MED/94274255
Bhushan V; Chandy M; Babu PG; Dennison D; Srivastava A; Saraswathi NK; John TJ; Department of Haematology, Christian Medical College & Hospital,; Vellore.
Seventy patients with congenital coagulation disorders (group A) and 202 other patients (group B) attending the Haematology clinic at the Christian Medical College and Hospital, Vellore ( India ) were screened for HIV infection between March 1989 and April 1991. Fifty five patients in


Occurrences, immunoglobulin classes, and biological activities of antibodies in normal human serum that are reactive with Cryptococcus neoformans glucuronoxylomannan.
Infect Immun. 1994 Jul;62(7):2857-64. Unique Identifier : AIDSLINE MED/94274302
Houpt DC; Pfrommer GS; Young BJ; Larson TA; Kozel TR; Department of Microbiology, University of Nevada, Reno 89557.
Serum obtained from normal human subjects contains antibodies reactive in an enzyme-linked immunosorbent assay with the glucuronoxylomannan (GXM) of Cryptococcus neoformans. The frequency of occurrence of class-specific antibodies among normal subjects was 28% for immunoglobulin G (IgG), 98% for IgM, and 3% for IgA. A


House calls: a support group for individuals with AIDS in a community residential setting.
Int J Group Psychother. 1994 Apr;44(2):133-52. Unique Identifier : AIDSLINE MED/94274350
Daniolos PT
The author describes a support group led by two psychiatrists for individuals with AIDS set in the participants residence, the AIDS Community Residence Association (ACRA) House. Similar to other AIDS groups described in the literature, the residents spoke of existential fears such as losing their physical beauty or i


Autoantibodies in thalassaemia major: relationship with oral iron chelator L1 [see comments]
J Assoc Physicians India. 1993 Jun;41(6):339-41. Unique Identifier : AIDSLINE MED/94274643
Mehta J; Chablani A; Reporter R; Singhal S; Mehta BC; Blood Research Centre, Bombay.
Ninety patients with thalassaemia major were investigated for the occurrence of antinuclear antibodies (ANA), and those with ANA were tested for antibodies to histones (AHA). ANA were detected in 7 of 27 thalassemics on oral iron chelator L1, and in 2 of 63 thalassaemics not on L1 (p


High-performance liquid chromatographic assay for the measurement of atovaquone in plasma.
J Chromatogr. 1994 Feb 11;652(2):211-9. Unique Identifier : AIDSLINE MED/94274808
DeAngelis DV; Long JD; Kanics LL; Woolley JL; Division of Pharmacokinetics and Drug Metabolism, Wellcome; Research Laboratories, Research Triangle Park, NC 27709.
A rapid and efficient isocratic high-performance liquid chromatographic assay for the measurement of atovaquone in plasma has been developed and validated. The drug was extracted from plasma with organic solvents, assayed on a C1 column with a mobile phase of methanol-0.1% acetic acid (70:30, v/v), and detected by ult


Detection of HIV-p24 antigen in body fluids by immunotrapping on Staphylococcus aureus (Cowan 1) bacteria, gold immunolabelling and backscattered electron analysis in a scanning electron microscope.
J Virol Methods. 1994 Mar;46(3):313-32. Unique Identifier : AIDSLINE MED/94274815
Katz D; Herrera MI; Cuevas L; Santa-Maria I; Casado C; Varela JM; Najera R; Department of Virology, Israel Institute for Biological Research,; Ness-Ziona.
An immunosorbent electron microscopical (ISEM) method, the Protein A-coated bacteria technique/gold, (PA-CBT/G), was developed for the detection of non-particulate soluble antigens. The method is based on immunotrapping of antigens on antibody coated, glutaraldehyde cross-linked, Protein A-rich, Staphylococcus aureus


Unusual pattern of reversible renal hyperechogenicity associated with acute myoglobinuric renal failure.
J Clin Ultrasound. 1994 May;22(4):279-81. Unique Identifier : AIDSLINE MED/94274897
Gollub MJ; Yee JM; Department of Radiology, New York University/Bellevue Hospital; Center, New York.
Desensitization to trimethoprim/sulfamethoxazole in HIV-infected patients.
J Allergy Clin Immunol. 1994 Jun;93(6):1001-5. Unique Identifier : AIDSLINE MED/94275029
Absar N; Daneshvar H; Beall G; Department of Medicine, Harbor-UCLA Medical Center, Torrance; 90509.
BACKGROUND: Trimethoprim-sulfamethoxazole (T/S) is an effective and important prophylactic medication for HIV-infected patients that must frequently be discontinued because of allergic reactions. OBJECTIVE: Our objective was to assess the safety, the frequency of success, and the duration of desensitization to T/S in


Gatekeeping through media format: strategies of voice for the HIV-positive via human interest news formats and organizations.
J Homosex. 1994;26(4):111-34. Unique Identifier : AIDSLINE MED/94275157
Hallett MA; Cannella D; Department of Criminal Justice Administration, Middle Tennessee; State University, Murfreesboro 37132.
This research examines the extent to which HIV-positive voices are marginalized in the mainstream versus the alternative press. The central claim of this research is that news media format considerations, constructed around what has come to be called media logic, leave persons who are HIV-positive with comparatively l


Integration of one's religion and homosexuality: a weapon against internalized homophobia?
J Homosex. 1994;26(4):91-110. Unique Identifier : AIDSLINE MED/94275164
Wagner G; Serafini J; Rabkin J; Remien R; Williams J; New York State Psychiatric Institute, NY 10032.
Internalized homophobia as a psychological phenomenon has attracted little systematic research despite its destructive impact on the mental health of the gay community. This study looks at the relationship between internalized homophobia and the process of integrating one s religious faith and homosexuality by compari


Epidemiology of psoriasis: clinical issues.
J Invest Dermatol. 1994 Jun;102(6):14S-18S. Unique Identifier : AIDSLINE MED/94275199
Krueger GG; Duvic M; Department of Medicine, University of Utah School of Medicine,; Salt Lake City.
Psoriasis is a genetically inherited spectrum of skin diseases characterized by epidermal proliferation and inflammation, which are reversible. Although many have reported that psoriasis is triggered by trauma, infections, stress, drugs, etc., the epidemiology of psoriasis remains poorly understood. Linkage to human l


Epidemiology of skin disease in HIV infection: a cohort study of health maintenance organization members.
J Invest Dermatol. 1994 Jun;102(6):34S-37S. Unique Identifier : AIDSLINE MED/94275204
Stern RS; Department of Dermatology, Beth Israel Hospital, Harvard Medical; School, Boston, Massachusetts 02215.
The medical literature suggests that persons infected with human immunodeficiency virus (HIV) have an increased risk of many common and uncommon cutaneous diseases. Further, it has been suggested that in HIV-infected people these conditions may be more persistent and they may be more prone to developing adverse cutane


Opposing regulatory effects of thioredoxin and eosinophil cytotoxicity-enhancing factor on the development of human immunodeficiency virus 1.
J Exp Med. 1994 Jul 1;180(1):359-63. Unique Identifier : AIDSLINE MED/94275391
Newman GW; Balcewicz-Sablinska MK; Guarnaccia JR; Remold HG; Silberstein DS; Department of Rheumatology and Immunology, Brigham and Women's; Hospital, Boston, Massachusetts 02115.
Exogenous recombinant human thioredoxin (rTRX, > or = 500 nM), a dithiol reductase enzyme, inhibited the expression of human immunodeficiency virus (HIV) 1BaL in human macrophages (M phi) by 71% (range, 26-100%), as evaluated by p24 antigen production and the integration of provirus at 14 d after infection. The stoich


Brief report: sexual transmission of hepatitis C.
J Med Virol. 1994 Mar;42(3):247-8. Unique Identifier : AIDSLINE MED/94275452
Skidmore SJ; Collingham KE; Drake SM; Regional Virus Laboratory/PHLS Birmingham, United Kingdom.
Inhibition of human immunodeficiency virus type 1 replication by nonionic block polymer surfactants.
J Med Virol. 1994 Mar;42(3):249-54. Unique Identifier : AIDSLINE MED/94275453
Hirschman SZ; Zucker ML; Garfinkel E; Department of Medicine, Mount Sinai School of Medicine, City; University of New York, New York 10029.
Eight block copolymers of hydrophilic polyoxyethylene and hydrophobic polyoxypropylene were examined for their effects on the replication of human immunodeficiency virus type 1 (HIV-1) in H9 cells. Although the polymers decreased cellular replication, they did not appear to be toxic to the cells; rather, they seemed t


Suppression of simian immunodeficiency virus replication in primary peripheral mononuclear cells by antisense RNA.
J Med Virol. 1994 Mar;42(3):255-8. Unique Identifier : AIDSLINE MED/94275454
Tung FY; Department of Pathology and Laboratory Medicine, College of; Medicine, University of Florida, Gainesville 32610-0275.
It has been demonstrated that human immunodeficiency virus (HIV) replication can be effectively blocked by an antisense sequence that was introduced into the lymphoid cell line through retroviral-mediated gene transfer. In this study, it is demonstrated that antisense RNA can also inhibit simian immunodeficiency virus


A study of oral candidiasis in HIV-positive patients.
J Dent Hyg. 1994 Jan-Feb;68(1):30-4. Unique Identifier : AIDSLINE MED/94275518
Van Meter F; Gallo JW; Garcia-Rojas G; Tan MM; Silverman S Jr; Division of Oral Medicine, Department of Stomatology, University; of California, San Francisco, School of Dentistry.
PURPOSE. Candidiasis may occur as the first clinical sign or symptom of HIV disease. Oral candidiasis was studied with respect to immunological status, and response to antifungal therapy in a group of HIV-positive individuals with a history of recurrent oral candidal infections. METHODS. Yeast cultures were obtained f


Throwing stones--choosing to care for PWA.
J Christ Nurs. 1994 Summer;11(3):30-2. Unique Identifier : AIDSLINE MED/94275615
Coles SM
Genomic alignment.
J Mol Evol. 1994 Mar;38(3):310-6. Unique Identifier : AIDSLINE MED/94275875
Hein J; Stovlbaek J; Institute of Biological Sciences, Aarhus University, Denmark.
As sequencing techniques become increasingly efficient, the average length of a sequence is bound to grow. Traditional sequence-comparison algorithms can either compare DNA or protein, but not a mixture, which is actually a common situation. Most obtained DNA sequences contain coding regions, and it is more reliable t


From the Centers for Disease Control and Prevention. Birth outcomes following zidovudine therapy in pregnant women [published erratum appears in JAMA 1994 Aug 3;272(5):349]
JAMA. 1994 Jul 6;272(1):17. Unique Identifier : AIDSLINE MED/94275946
[Adult T-cell leukemia, HTLV-I associated bronchopneumonopathy]
Nippon Rinsho. 1994 Mar;Suppl 4:673-5. Unique Identifier : AIDSLINE MED/94276158
Tashiro T; Second Department of Internal Medicine, Oita Medical University.
[Pulmonary lesions in AIDS]
Nippon Rinsho. 1994 Mar;Suppl 4:683-6. Unique Identifier : AIDSLINE MED/94276161
Koike M; Department of pathology, Tokyo Metropolitan Komagome Hospital.
[Interstitial pneumonia in patients with human T-cell lymphotropic virus type-1 infection]
Nippon Kyobu Shikkan Gakkai Zasshi. 1993 Dec;31 Suppl:36-41. Unique Identifier : AIDSLINE MED/94276373
Sugimoto M; Department of Medicine, Kumamoto City Hospital, Japan.
Pulmonary involvement has been demonstrated in patients with human T-cell lymphotropic virus type-1 (HTLV-1)-associated myelopathy (HAM/TSP) or with HTLV-1 uveitis. Pulmonary lesions in these patients are characterized by T-lymphocyte alveolitis. Interestingly, HLTV-1-infected cells were markedly increased in bronchoa


[Two pulmonary tuberculosis cases with HIV infection]
Kekkaku. 1994 May;69(5):367-74. Unique Identifier : AIDSLINE MED/94276427
Wada M; Yamamoto S; Ogata H; Sugita N; Kino T; Hayashi A; Research Institute of Tuberculosis, Japan Anti-Tuberculosis; Association, Tokyo.
It was reported that HIV-infected persons were at much higher risk to develop active tuberculosis than HIV-none-infected persons, about 10% of whom might develop active tuberculosis through their lives, almost identical percentage of HIV-infected persons had developed active tuberculosis annually. In


[9th International AIDS Conference in Berlin]
Kango. 1993 Sep;45(11):22-3. Unique Identifier : AIDSLINE MED/94276439
Toida M
K(+)-sparing diuretic actions of trimethoprim: inhibition of Na+ channels in A6 distal nephron cells.
Kidney Int. 1994 Apr;45(4):1070-6. Unique Identifier : AIDSLINE MED/94276480
Schlanger LE; Kleyman TR; Ling BN; Emory University School of Medicine, Department of Medicine,; Atlanta, Georgia.
Hyperkalemia complicates trimethoprim-sulfamethoxazole (TMP-SMX) therapy in over 20% of HIV-infected patients. TMP is a heterocyclic weak base, similar to amiloride, a K(+)-sparing diuretic and Na+ channel blocker. Apical TMP is known to inhibit amiloride-sensitive short circuit current in A6 cells, a tissue culture m


Tuberculosis: medical students at risk [see comments]
Med J Aust. 1994 Apr 4;160(7):395-7. Unique Identifier : AIDSLINE MED/94276907
Wilkins D; Woolcock AJ; Cossart YE; Student Health Services, University of Sydney, NSW.
In 1979 an outbreak of tuberculosis occurred in medical students at the University of Sydney. Eight of 35 Mantoux-negative students who attended the autopsy of an immunosuppressed patient with unsuspected active tuberculosis became infected and one developed clinical disease. A report of the incident was prepared for


Needlestick injury in medical students [see comments]
Med J Aust. 1994 Apr 4;160(7):398-400. Unique Identifier : AIDSLINE MED/94276908
deVries B; Cossart YE; Department of Infectious Diseases, University of Sydney, NSW.
OBJECTIVE: To determine the incidence of needlestick injuries and the prevalence of hepatitis B vaccination among medical students, dentistry students, and hospital staff. DESIGN AND SUBJECTS: Anonymous survey of final year medical students and dentistry students enrolled at Sydney University in 1992, and nursing staf


Relative infrequency of microsporidial infection in HIV infected patients in Queensland [letter]
Med J Aust. 1994 Apr 4;160(7):452-3. Unique Identifier : AIDSLINE MED/94276932
Cominos D; Paterson DL; Walker NI; Allworth AM; Kemp RJ
AZT reduces HIV transmission to newborns [news]
Minn Med. 1994 Apr;77(4):57. Unique Identifier : AIDSLINE MED/94276984
Minnesota reports 2,000th AIDS case [news]
Minn Med. 1994 Apr;77(4):57. Unique Identifier : AIDSLINE MED/94276985
Novel interactions between human T-cell leukemia virus type I Tax and activating transcription factor 3 at a cyclic AMP-responsive element.
Mol Cell Biol. 1994 Jul;14(7):4958-74. Unique Identifier : AIDSLINE MED/94277101
Low KG; Chu HM; Schwartz PM; Daniels GM; Melner MH; Comb MJ; Laboratory of Molecular Neurobiology, Massachusetts General; Hospital, Charlestown 02129.
Human proenkephalin gene transcription is transactivated by human T-cell leukemia virus type I (HTLV-I) Tax in human Jurkat T lymphocytes. This transactivation was further enhanced in Jurkat cells treated with concanavalin A, cyclic AMP, or 12-O-tetradecanoylphorbol-13-acetate. Deletion and cis-element transfer analys


Report prompts US to enter talks on new split of AIDS patent royalties [news]
Nature. 1994 Jun 30;369(6483):693. Unique Identifier : AIDSLINE MED/94277186
Macilwain C; Butler D
Allain loses appeal and faces threat of new charges [news]
Nature. 1994 Jun 30;369(6483):694. Unique Identifier : AIDSLINE MED/94277188
Butler D
Malaria and AIDS [letter]
Nature. 1994 Jun 30;369(6483):700. Unique Identifier : AIDSLINE MED/94277192
Sharma VP
The pattern and cost of hospital care for persons with HIV/AIDS in Guilford County, NC, 1987-1991.
N C Med J. 1994 Apr;55(4):131-4. Unique Identifier : AIDSLINE MED/94277219
Allison-Cooke S; National Perinatal Information Center, Providence, Rhode Island.
Screening for human immunodeficiency virus in physicians. Who should we test and what will it cost [see comments]
N C Med J. 1994 Apr;55(4):136-40. Unique Identifier : AIDSLINE MED/94277220
Levine AA; Sandler RS; Department of Nutrition, UNC School of Public Health, Chapel Hill; 27599.
[HIV-positive blood donors, 1985-1993]
Ned Tijdschr Geneeskd. 1994 May 28;138(22):1135. Unique Identifier : AIDSLINE MED/94277269
Dudok de Wit C; College voor de Bloedtransfusie van het Nederlandse Rode Kruis,; Amsterdam.
It's time to take another look at New York's confidentiality law [see comments]
N Y State Dent J. 1994 May;60(5):14-5. Unique Identifier : AIDSLINE MED/94277458
Kotlow LA
AMA releases HIV, smoking guidelines [news]
Pa Med. 1994 Apr;97(4):30. Unique Identifier : AIDSLINE MED/94277581
Q&A supplements new state HIV guidelines [news]
Pa Med. 1994 Apr;97(4):30. Unique Identifier : AIDSLINE MED/94277582
Evaluation and management of early HIV infection.
Pa Nurse. 1994 May;49(5):14-5. Unique Identifier : AIDSLINE MED/94277588
Important things to remember about early HIV infection.
Pa Nurse. 1994 May;49(5):15. Unique Identifier : AIDSLINE MED/94277589
AZT reduced rate of maternal transmission of HIV [news]
Pa Nurse. 1994 May;49(5):6. Unique Identifier : AIDSLINE MED/94277593
New findings and symptomatic treatment for neurolathyrism, a motor neuron disease occurring in north west Bangladesh.
Paraplegia. 1994 Mar;32(3):193-5. Unique Identifier : AIDSLINE MED/94277618
Haque A; Hossain M; Khan JK; Kuo YH; Lambein F; De Reuck J; Department of Neurology, Institute of Postgraduate Medicine and; Research, Dhaka, Bangladesh.
Neurolathyrism is a form of spastic paraparesis caused by the neuroexcitatory amino acid 3-N-oxalyl-L-2,3-diaminopropanoic acid (beta-ODAP) present in the seeds and foliage of Lathyrus sativus. The disease is irreversible and usually nonprogressive. Tolperisone HCl, a centrally acting muscle relaxant, has been shown t


A 26-year-old HIV-positive hemophiliac with knee pain.
Orthop Rev. 1994 Apr;23(4):339-43. Unique Identifier : AIDSLINE MED/94277641
Heim M; Horoszowski H; Department of Orthopaedic Rehabilitation, Chaim Sheba Medical; Center, Tel-Hashomer Hospital, Israel.
The following case is presented to illustrate the roentgenographic and clinical findings of a condition of interest to the orthopaedic surgeon. Initial history, physical findings, and roentgenographic examinations are found on the first page. The final clinical and roentgenographic differential diagnoses are presented


Hepatic spindle cell tumors in HIV positive children.
Pediatr Radiol. 1994;24(1):78-9. Unique Identifier : AIDSLINE MED/94277708
Levin TL; Adam HM; van Hoeven KH; Goldman HS; Department of Radiology, Babies Hospital, Columbia-Presbyterian,; New York, NY 10032.
Spindle cell tumors (leiomyoma, leiomyosarcoma) have been described in HIV infected children involving the gastrointestinal tract, respiratory tract and liver. The same tumor has been reported in immunocompromised children following liver and renal transplantation. A case of hepatic spindle cell tumor in an HIV infect


The incidence of prenatal syphilis at the Boston City Hospital: a comparison across four decades.
Pediatrics. 1994 Jul;94(1):24-8. Unique Identifier : AIDSLINE MED/94277734
Klass PE; Brown ER; Pelton SI; Department of Pediatrics, Boston University School of Medicine,; MA.
OBJECTIVE. To examine the incidence and epidemiologic correlates of congenital syphilis at an inner-city Boston hospital, and draw comparisons with the situation at the same hospital 40 years ago. DESIGN. Chart review and comparison with data collected in 1951. SETTING. Maternity and pediatric services at Boston City


Let's talk about sex [news]
Nurs Times. 1994 May 11-17;90(19):20. Unique Identifier : AIDSLINE MED/94277764
Cohen P
HIV/AIDS--lessons from Zimbabwe.
Nurs Times. 1994 May 25-31;90(21):46-8. Unique Identifier : AIDSLINE MED/94277803
Stephen S
Infection control. Safe practice.
Nurs Times. 1994 May 25-31;90(21):64, 66, 68. Unique Identifier : AIDSLINE MED/94277807
Pratt R
Gulf nurses face enforced HIV tests to renew contracts [news]
Nurs Times. 1994 May 25-31;90(21):8. Unique Identifier : AIDSLINE MED/94277808
Retroviral synthetic peptide serum antibodies in human sporadic amyotrophic lateral sclerosis.
Peptides. 1994;15(2):207-14. Unique Identifier : AIDSLINE MED/94277849
Westarp ME; Foring B; Rasmussen H; Schraff S; Mertens T; Kornhuber HH; Ulm University Department of Neurology, Germany.
We examined 101 sera from 32 adult sporadic amyotrophic lateral sclerosis (ALS) patients, including nine with positive enzyme-linked immunosorbent assay (ELISA) serum antibodies against human spuma retrovirus (HSRV) [human foamy virus (HFV)] envelope (env) and/or capsid (gag) proteins, for peptide seroreactivity. Synt


Naked megakaryocyte nuclei in bone marrows of patients with acquired immunodeficiency syndrome: a somewhat specific finding.
Mod Pathol. 1994 Feb;7(2):166-8. Unique Identifier : AIDSLINE MED/94277970
Gordon S; Lee S; Department of Pathology and Laboratory Medicine, Cedars-Sinai; Medical Center, Los Angeles, California.
Naked megakaryocyte nuclei (NMN) were studied retrospectively in 100 bone marrow biopsy sections and aspirates from patients with acquired immunodeficiency syndrome (AIDS) and 124 non-AIDS controls. An NMN score was developed to semiquantitate the NMN. The AIDS bone marrows had an incidence of 97% and a mean NMN score


A crisis offering an opportunity for growth. Burnout in AIDS care.
Prof Nurse. 1994 May;9(8):544-8. Unique Identifier : AIDSLINE MED/94278004
Tavares M
The intense and demanding nature of Aids/HIV care makes burnout hard to avoid. This article describes how professionals suffering from burnout can access new sources of energy that offer the potential for growth and renewal.


But the horse has left the stable [editorial]
Quintessence Int. 1994 Mar;25(3):151-2. Unique Identifier : AIDSLINE MED/94278047
Neidle EA
[Scintigraphy with gallium-67 citrate in patients with AIDS: pathologic extrapulmonary uptake]
Radiol Med (Torino). 1994 May;87(5):683-7. Unique Identifier : AIDSLINE MED/94278150
Brunetti A; Mangoni di S Stefano ML; Chirianni A; Bonadies G; Celentano L; Foggia M; Tedeschi E; Cataldo PT; Piazza M; Salvatore M; Cattedra di Medicina Nucleare, Universita Federico II, Napoli.
67Gallium citrate can accumulate in different inflammatory and neoplastic lesions. The mechanisms of 67Gallium uptake in abnormal tissue are still partially unknown and the tracer is considered a nonspecific indicator of disease. In AIDS patients, 67Gallium citrate is used in the diagnosis and characterization of oppo


Leptospirosis patient with AIDS: the first case reported.
Rev Soc Bras Med Trop. 1994 Jan-Mar;27(1):39-42. Unique Identifier : AIDSLINE MED/94278168
Neves E de S; Pereira MM; Galhardo MC; Caroli A; Andrade J; Morgado MG; Mendes RP; Hospital Evandro Chagas, Department of Bacteriology, Instituto; Oswaldo Cruz/Fundacao Oswaldo Cruz, Rio de Janeiro, Brasil.
A case of renal icterohemorrhagic leptospirosis involving a patient with acquired immunodeficiency syndrome (AIDS) is reported. Despite the low levels of CD4+ T lymphocytes, the clinical course of leptospirosis was similar to that observed in non-immunodepressed patients, and no worsening of AIDS occurred due to the i


[HTLV-II infection in parenteral drug addicts from western Andalucia]
Rev Clin Esp. 1994 Feb;194(2):104-6. Unique Identifier : AIDSLINE MED/94278180
Merino Munoz D; Marquez P; Ollero Baturone M; Alcoucer Diaz R; Gimeno A; Martin Suarez I; Pujol de la Llave E; Servicio de Medicina Interna, Hospital Manuel Lois, Huelva.
The epidemiology of retrovirus HTLV-II is scarcely known even though it appears to be narrowly related to parenteral drug addiction. In order to find out the prevalence of HTLV-II among IVDU in our area, the sera of 137 subjects who came to our center for clinical evaluation were analyzed. The presence of HTLV-I/II an


[Pneumococcal endocarditis and Pneumocystis carinii pneumonia in a patient with HIV infection (letter)]
Rev Clin Esp. 1994 Feb;194(2):136. Unique Identifier : AIDSLINE MED/94278186
Miguelez M; Linares Feria M; Laynez P
[Prolonged survival in patients with progressive multifocal leukoencephalopathy associated with AIDS treated with high doses of zidovudine (letter)]
Rev Clin Esp. 1994 Feb;194(2):136-8. Unique Identifier : AIDSLINE MED/94278187
Martin-Suarez I; Aguayo Canela M; Merino Munoz D; Pujol de la Llave E
[AIDS in the elderly (letter)]
Rev Clin Esp. 1994 Feb;194(2):138-9. Unique Identifier : AIDSLINE MED/94278188
Galindez J; Soriano V; Gonzalez-Lahoz J
[Tuberculous pericarditis. Clinical aspects in patients with or without AIDS (letter; comment)]
Rev Clin Esp. 1994 Feb;194(2):139-40. Unique Identifier : AIDSLINE MED/94278189
de Miguel J; Pedreira JD
[Human immunodeficiency virus infection and tuberculosis: who should receive chemoprophylaxis? (editorial; comment)]
Rev Clin Esp. 1994 Feb;194(2):73-4. Unique Identifier : AIDSLINE MED/94278191
Moreno Guillen S
[Decision regarding chemoprophylaxis with isoniazid in patients using parenteral drugs and infected with HIV (see comments)]
Rev Clin Esp. 1994 Feb;194(2):81-6. Unique Identifier : AIDSLINE MED/94278193
Sanchez Fuentes D; Barragan Casas JM; Garcinuno Jimenez MA; Martin Casado M; Martin Marcos M; Servicio de Medicina Interna, Hospital Nuestra Senora de; Sonsoles, Avila.
OBJECTIVES: Analyze the decision to enact or to refrain from chemoprophylaxis (CP) with isoniazide (INH) in patients who are intravenous drug users (IVDU) in Spain infected by the human immunodeficiency virus (HIV), either classified or not with hypersensitive skin tests. METHODS: W


[Clinical characteristicsand course of extrapulmonary/disseminated tuberculosis in patients with AIDS. Study of 103 cases diagnosed in the province of Cadiz]
Rev Clin Esp. 1994 Feb;194(2):87-97. Unique Identifier : AIDSLINE MED/94278194
Canueto Quintero J; Bascunana Quirell A; Vergara de Campos A; Torres-Tortosa M; Escribano Moriana JC; Sanchez Porto A; Perez Cortes S; Perez Jimenez J; Lorente Campos J
Tuberculosis constitutes a public health problem that has become more serious in the past couple of years primarily due to the pandemic of human immunodeficiency virus (HIV). This study analyzes the evolutionary, clinical, and epidemiological characteristics of the extrapulmonary and disseminated forms of tuberculosis


Impairment of exercise capacity in various groups of HIV-infected patients.
Respiration. 1994;61(2):80-5. Unique Identifier : AIDSLINE MED/94278246
Pothoff G; Wassermann K; Ostmann H; Medical Clinic III, University of Cologne, FRG.
It is known that pulmonary function is impaired during the course of HIV infection even in early stages. In order to estimate the resulting reduction of exercise capacity, different groups of HIV patients were investigated. Group 1 consisted of 20 patients without a history of respiratory disease and without actual lu


[Prognostic role of pregnancy on the course of HIV infection: a retrospective cohort study (1985-92)]
Rev Med Interne. 1993;14(10):1000. Unique Identifier : AIDSLINE MED/94278252
Morlat P; Hocke C; Chene G; Lasseur C; Dupon M; Monlun E; Bonnal F; Constans J; Lacoste D; Ragnaud JM; et al; Centre d'information et de soins de l'immunodeficience humaine,; CHRU de Bordeaux.
In a hospital-based cohort study of HIV-infected patients, we compare the progression of the disease (occurrence of CDC group IV, death, decline of CD4 below 200/mm3) between 55 women with delivery and 89 matched control HIV positive women with no history of pregnancy. After a mean follow-up of three years, no signifi


[Risk factors of cerebral toxoplasmosis in patients with HIV infection: data of a primary prevention trial]
Rev Med Interne. 1993;14(10):1001. Unique Identifier : AIDSLINE MED/94278253
Pueyo S; Leport C; Chene G; Morlat P; Hafner R; Vilde JL; Luft B; Salamon R; Aubertin J; Inserm U330, Universite de Bordeaux II.
To identify risk factors for cerebral toxoplasmosis (CT) in HIV patients (pts) with positive serology for Toxoplasma gondii and CD4


[Primary prevention of cerebral toxoplasmosis in patients with HIV infection: results of a double-blind randomized trial, pyrimethamine versus placebo]
Rev Med Interne. 1993;14(10):1002. Unique Identifier : AIDSLINE MED/94278254
Morlat P; Chene G; Leport C; Rousseau F; Luft B; Aubertin J; Hafner R; Salamon R; Vilde JL; Service de medecine interne, hopital Saint-Andre, Bordeaux.
To assess the efficacy of pyrimethamine (Pyr) for primary prophylaxis of cerebral toxoplasmosis (CT) in HIV patients (pts), 554 pts were randomized in a double-blind, placebo-controlled trial (mean follow-up: 14 months). The intent-to-treat analysis found no significant difference in the incidence of ct at 1 year: 12%


[Membrane fatty acids and blood antioxidants in 77 patients with HIV infection]
Rev Med Interne. 1993;14(10):1003. Unique Identifier : AIDSLINE MED/94278255
Constans J; Pellegrin JL; Peuchant E; Thomas MF; Dumon MF; Sergeant C; Simonoff M; Pellegrin I; Brossard G; Barbeau P; et al; Service de medecine interne et pathologie vasculaire, hopital; Saint-Andre, Bordeaux.
We have measured the fatty acid (FA) composition of erythrocyte membranes and plasma anti-oxidants in HIV+ patients. Saturated FA are higher and poly-unsaturated FA lower than in controls (P = 0.02). Selenium (Se) is lower in patients less than 400 CD4 cells/mm3 (P = 0.002). Vitamin A is lower in the HIV+ regardless o


[Interferon and blood tumor necrosis factor in 95 patients with HIV infection]
Rev Med Interne. 1993;14(10):1004. Unique Identifier : AIDSLINE MED/94278256
Constans J; Pellegrin JL; Pellegrin I; Peuchant E; Dumon MF; Sergeant C; Simonoff M; Brossard G; Barbeau P; Clerc M; et al; Service de medecine interne et pathologie vasculaire, hopital; Saint-Andre, Bordeaux.
We have measured TNF-alpha and interferon alpha in 95 HIV positive patients and 20 healthy subjects. TNF-alpha was higher in the HIV+ patients (P = 0.0001) and was correlated to the CD4 cell count (P = 0.02) and cholesterol (negatively) (P = 0.04). Interferon-alpha was correlated to the wasting syndrome (P = 0.002), h


[Value and limitations of the endomyocardial biopsy in HIV infection]
Rev Med Interne. 1993;14(10):1032. Unique Identifier : AIDSLINE MED/94278283
Barbeau P; Pellegrin JL; Labouyrie E; Brossard G; Rispal P; Lasseur C; Leng B; Clinique de medecine interne et Maladies Infectieuses, CHU de; Bordeaux, hopital Haut Leveque, Pessac.
The authors evaluated the interest of endomyocardial biopsy in 19 consecutively hospitalized patients with AIDS. Histopathological study dit not exhibit opportunistic infection but showed aspecific myocarditis in nine patients.


[Hodgkin's disease and HIV infection. Study of 40 cases]
Rev Med Interne. 1993;14(10):959. Unique Identifier : AIDSLINE MED/94278312
Khennane M; Jaccard A; Gabarre J; d'Agay MF; Oksenhendler E; Clauvel JP; Service d'immuno-hematologie, hopital Saint-Louis, Paris.
Hodgkin s disease seems to be more frequent in HIV infected patients than in general population with peculiar clinical and pathological aspects. We describe 40 cases of Hodgkin s disease in HIV infected patients followed between 1983 and 1993.


[Pulmonary pneumocystosis in immunodepression: apropos of 78 consecutive cases seen at the CHRU of Clermont-Ferrand from 1984 to 1993]
Rev Med Interne. 1993;14(10):963. Unique Identifier : AIDSLINE MED/94278316
Laurichesse H; Cambon M; Conductier R; Fouilhoux A; Jannicot H; Roux D; Deteix P; Demeocq F; Travade P; Beytout J; Service des maladies infectieuses et tropicales, Hotel-Dieu,; CHRU de Clermont-Ferrand.
78 consecutive cases of PCP have been analysed: 59 (75.6%) cases were associated with HIV infection and 19 (24.4%) cases were associated with solid tumors and hematologic malignancies at advanced stage of the disease and renal transplantation. It could suggest primary prevention for such patients.


[Evaluation of the epidemic caused by the human immunodeficiency virus in Cambodia]
Rev Med Interne. 1993;14(10):997. Unique Identifier : AIDSLINE MED/94278347
Guerin B; L'Her P; Lenegre-Thourin I; Kruy SL; Tea P; Tea P; Oung C; Service de Medecine, hopital Calmette, Phnom Penh, Cambodge.
The infection by the human immunodeficiency virus is in the process of expanding to a dramatical level in South East Asia. At the moment, the few available datas on Cambodia are increasingly worrying, with a rate of seropositivity of prostitutes higher than 9% in 1992 and a clear


[HIV infection in intravenous drug addicts]
Rev Med Interne. 1993;14(10):998. Unique Identifier : AIDSLINE MED/94278348
Boissonnas A; Wautelet V; Salmon D; Sereni D; Sicard D; Christoforov B; Departement de medecine interne, hopital Cochin, Paris.
Clinical course of HIV infection was studied among 156 intravenous drug users (IVDU). Mean follow up was 22.7 months. Characteristics of HIV infection in IVDU were frequent oral candidiasis and bacterial infections (BI), more frequent progression to AIDS after a second BI, rapid decline of CD4+ in a group of current I


[Behaviors at risk of the intravenous drug addicts and prevention of HIV infection]
Rev Med Interne. 1993;14(10):999. Unique Identifier : AIDSLINE MED/94278349
Boissonnas A; Pinquier JL; Christoforov B; Service de medecine interne, hopital Cochin, Paris.
Needle sharing and sexual behaviour were studied in 396 intraveinous drug addicts (IVDA). Only 20% stopped needle sharing and used condoms. They were 6% before 1990 and 23% after. Both preventive measures were adopted by 32 of 78 HIV positive and only 25 of 210 HIV negative IVDA. Attention is drawn on the need for spe


Lethal cytomegalovirus adrenalitis in a case of AIDS.
Scand J Urol Nephrol. 1994 Mar;28(1):105-6. Unique Identifier : AIDSLINE MED/94278448
Angulo JC; Lopez JI; Flores N; Department of Urology, Basurto Hospital, Bilbao, Spain.
The clinico-pathologic report of a case of cytomegalovirus ( CMV ) necrotizing adrenalitis arising in an intravenous drug-abuser and HIV-infected young is presented. CMV urinary tract infection, genital Kaposi s, and demyelinat


AIDS vaccine research. U.S. panel votes to delay real-world vaccine trials [news]
Science. 1994 Jun 24;264(5167):1839. Unique Identifier : AIDSLINE MED/94278471
Cohen J
[The work of the nurse's aide. Care of an AIDS patient]
Soins. 1994 Mar;(582):30-2. Unique Identifier : AIDSLINE MED/94278585
Bouche F
[Mother-child AIDS: nursing care]
Soins Gynecol Obstet Pueric Pediatr. 1993 Dec-1994 Jan;(151-152):49-60. Unique Identifier : AIDSLINE MED/94278661
Guyonnet M
[Neuromuscular disorders of the extremities after heroin-induced rhabdomyolysis]
Tidsskr Nor Laegeforen. 1994 Feb 10;114(4):432-4. Unique Identifier : AIDSLINE MED/94278760
Rasmussen FO; Rand-Henriksen S; Stanghelle JK; Sunnaas sykehus, Ulleval sykehus, Oslo.
We describe four patients with neuromuscular deficiencies after heroin-induced rhabdomyolysis. Such deficiencies have a good prognosis, but all our patients continued to have sequelae. In an emergency situation one should always consider fasciotomy for acute compartment syndromes. Two of our patients developed a Volkm


[AIDS in Africa can be conquered]
Tidsskr Nor Laegeforen. 1994 Apr 10;114(9):1038. Unique Identifier : AIDSLINE MED/94278796
Bergstrom S; Kvinneklinikken Ulleval sykehus, Oslo.
[Sexually transmitted diseases, HIV infection and AIDS in Mudzi, Zimbabwe. A study of knowledge, attitudes and practice in a rural area in southern Africa]
Tidsskr Nor Laegeforen. 1994 Apr 10;114(9):1045-9. Unique Identifier : AIDSLINE MED/94278799
Rygnestad T; Hana J; Myhre AK; Ministry of Health and Child Welfare, Mudzi, Zimbabwe.
We describe a study conducted in a rural area of Zimbabwe . We examined all patients who attend for treatment of a presenting sexually transmitted disease for a period of one month in 1989 and 1992. In addition we studied the knowledge of, attitudes towards and practices as regard


[HIV-prevalence in Mutoko, Zimbabwe. A study among pregnant women and patients with sexually transmitted diseases]
Tidsskr Nor Laegeforen. 1994 Apr 10;114(9):1050-2. Unique Identifier : AIDSLINE MED/94278800
Forland F; Eriksen K; Mutoko District Hospital, Zimbabwe.
The Ministry of Health and Child Welfare in Zimbabwe has carried out a number of surveys in different districts of Zimbabwe to determine the extent of the HIV-epidemic. In Mutoko district such a study was carried out to determine the HIV-prevalence among pregnant women and patien


[Experiences and strategies of AIDS preventive work in Mudzi and Mutoko. Experiences from 2 rural districts in Zimbabwe]
Tidsskr Nor Laegeforen. 1994 Apr 10;114(9):1089-91. Unique Identifier : AIDSLINE MED/94278810
Eriksen K; Forland F; Rygnestad T; Mutoko District Hospital, Zimbabwe.
[Priority decisions in hospital departments (letter; comment)]
Tidsskr Nor Laegeforen. 1994 Apr 10;114(9):1107-8. Unique Identifier : AIDSLINE MED/94278821
Froland SS
Evaluation and management of early HIV infection.
Todays OR Nurse. 1994 May-Jun;16(3):50-1. Unique Identifier : AIDSLINE MED/94278870
Moore AS
[AIDS and heart disease]
Ugeskr Laeger. 1994 Mar 28;156(13):1940-4. Unique Identifier : AIDSLINE MED/94278980
Lindvig K; Nielsen TL; Hansen BF; Kardiologisk laboratorium, Kobenhavns Amts Sygehus i Gentofte.
This article reviews cardiac manifestations of AIDS in terms of etiology, pathogenesis, pathoanatomic lesions and heart function. Hypothetically the prevalence of myocarditis and disperse fibrosis of the myocardium are correlated to increasing rates of dilated cardiomyopathy and cardiac insufficiency. Echocardiography


[AIDS with apoplectic onset]
Ugeskr Laeger. 1994 Feb 28;156(9):1313-4. Unique Identifier : AIDSLINE MED/94279057
Gam J; Korbo L; Andersen J; Neuromedicinsk afdeling, Bispebjerg Hospital, Kobenhavn.
Four cases with an apoplectic debut of AIDS are reported. Two of the patients had not earlier been identified as being HIV-positive. In three patients, the underlying cause was probably cerebral toxoplasmosis. It is important to consider AIDS in the differential diagnosis of stroke, particularly in young adults.


[AIDS-risk and blood transfusion (letter)]
Ugeskr Laeger. 1994 Feb 28;156(9):1325. Unique Identifier : AIDSLINE MED/94279063
Larsen MO
Bovine immunodeficiency-like virus--a potential cause of disease in cattle?
Vet Rec. 1994 Mar 19;134(12):289-91. Unique Identifier : AIDSLINE MED/94279088
Brownlie J; Collins ME; Heaton P; Agricultural and Food Research Council, Institute for Animal; Health, Compton, Newbury, Berkshire.
Clinical aspects of Chlamydia psittaci infection in cats infected with feline immunodeficiency virus.
Vet Rec. 1994 Apr 9;134(15):365-8. Unique Identifier : AIDSLINE MED/94279102
O'Dair HA; Hopper CD; Gruffydd-Jones TJ; Harbour DA; Waters L; Department of Veterinary Medicine, School of Veterinary Science,; University of Bristol, Langford.
Two groups of six cats were established, one a control group and one infected with feline immunodeficiency virus (FIV) 18 months previously. The cats in both groups were inoculated with Chlamydia psittaci and the clinical progression of the infection was monitored by means of a clinical scoring system for 10 months. H


A Rev protein is expressed in caprine arthritis encephalitis virus (CAEV)-infected cells and is required for efficient viral replication.
Virology. 1994 Jul;202(1):1-15. Unique Identifier : AIDSLINE MED/94279130
Schoborg RV; Saltarelli MJ; Clements JE; Johns Hopkins University School of Medicine, Baltimore, Maryland; 21205.
Caprine arthritis encephalitis virus (CAEV) is a lentivirus that is closely related to visna virus and more distantly related to the human lentivirus human immunodeficiency virus 1 (HIV-1). Like other lentiviruses, the genome of CAEV contains multiple small ORFs that encode viral regulatory proteins. Sequence analysis


Functional significance of the dinucleotide bulge in stem-loop1 and stem-loop2 of HIV-2 TAR RNA.
Virology. 1994 Jul;202(1):202-11. Unique Identifier : AIDSLINE MED/94279141
Rhim H; Rice AP; Division of Molecular Virology, Baylor College of Medicine,; Houston, Texas 77030.
Human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) encode related proteins called Tat-1 and Tat-2, respectively, that bind directly to the TAR RNA element contained at the 5 ends of viral transcripts and thereby stimulate transcription through an as yet unidentified mechanism. The determinants in the HIV-1


Primate T-lymphotropic virus type I LTR sequence variation and its phylogenetic analysis: compatibility with an African origin of PTLV-I.
Virology. 1994 Jul;202(1):212-23. Unique Identifier : AIDSLINE GENBANK/Z32527
Vandamme AM; Liu HF; Goubau P; Desmyter J; Rega Institute for Medical Research, Leuven, Belgium.
Due to the low evolutionary rate and the limited horizontal transmission of human T-lymphotrophic virus type I (HTLV-I), its phylogenetic analysis reveals the movements and contacts of ancient populations. Since simian strains cannot be distinguished from human strains by phylogenetic criteria, this virus has appropri


Analysis of binding elements in the human immunodeficiency virus type 1 genomic RNA and nucleocapsid protein.
Virology. 1994 Jul;202(1):233-46. Unique Identifier : AIDSLINE MED/94279144
Berkowitz RD; Goff SP; Department of Biochemistry and Molecular Biophysics, College of; Physicians and Surgeons, Columbia University, New York, New York; 10032.
We previously used RNA gel mobility shift assays to demonstrate specific binding of the HIV-1 gag precursor polyprotein and nucleocapsid (NC) protein to HIV-1 RNA and to map the binding elements in each species by mutagenesis. Here we report finer mapping of binding elements in the HIV-1 genomic RNA and NC protein, pe


Biological importance and cooperativity of HIV-1 regulatory gene splice acceptors.
Virology. 1994 Jul;202(1):264-71. Unique Identifier : AIDSLINE MED/94279148
Riggs NL; Little SJ; Richman DD; Guatelli JC; Department of Medicine, University of California at San Diego.
The replication of HIV-1 mutants containing altered splice acceptor sequences was studied. The splice acceptor sites 5 of the essential tat and rev AUG codons were altered to eliminate specifically spliced species from the viral repertoire of mRNAs. All splice site mutants were attenuated or fully defective. Mutation


HIV-2 EHO isolate has a divergent envelope gene and induces single cell killing by apoptosis.
Virology. 1994 Jul;202(1):471-6. Unique Identifier : AIDSLINE GENBANK/U27200
Rey-Cuille MA; Galabru J; Laurent-Crawford A; Krust B; Montagnier L; Hovanessian AG; Department of AIDS and Retroviruses, UA CNRS 1157, Institut; Pasteur, Paris, France.
The human immunodeficiency virus type 2 (HIV-2)-related isolate, referred to as HIV-2 EHO, has been isolated from an Ivory Coast patient with acquired immunodeficiency syndrome (AIDS). Infection of CD4 expressing cells with this highly infectious virus mediates a cytopathic ef


The Rev protein of visna virus is localized to the nucleus of infected cells.
Virology. 1994 Jul;202(1):485-90. Unique Identifier : AIDSLINE MED/94279175
Schoborg RV; Clements JE; Johns Hopkins University School of Medicine, Baltimore, Maryland; 21205.
Visna virus is a lentivirus of sheep that is distantly related to the human lentivirus HIV-1. Like other lentiviruses, the genome of visna virus contains multiple small open reading frames that encode viral regulatory proteins. The product of one of these regulatory genes is the visna virus Rev protein, Rev-V. In this


Induction of developmentally programmed cell death and activation of HIV by sodium butyrate.
Virology. 1994 Jul;202(1):513-8. Unique Identifier : AIDSLINE MED/94279181
Sadaie MR; Hager GL; Division of Transfusion Transmitted Diseases, Food and Drug; Administration, Rockville, Maryland 20852.
Apoptosis is an important regulatory process during normal development and maturation. We find that the proliferation-arresting and differentiation-inducing compound sodium n-butyrate (NaB) triggers a marked host chromatin degradation. This apoptotic process is independent of, but commensurate with, a rapid increase i


A truncated HTLV-I envelope protein, lacking the hydrophobic membrane anchor domain, is associated with cellular membranes and virions.
Virology. 1994 Jul;202(1):61-9. Unique Identifier : AIDSLINE MED/94279182
Carrington CV; Weiss RA; Schulz TF; Chester Beatty Laboratories, Institute of Cancer Research,; London, United Kingdom.
The HTLV-I producer cell line C10/MJ2 does not induce syncytium formation with HTLV-I receptor expressing cells. Here we show that this cell line produces a truncated envelope protein, which, because of a premature stop codon, lacks the hydrophobic membrane anchor domain of the transmembrane protein (TM). Despite lack


The surgeon, needle-sticks, and HIV [see comments]
Wis Med J. 1994 Mar;93(3):109-13. Unique Identifier : AIDSLINE MED/94279196
Kranendonk DH
This review article looks at needle-stick injuries and human immunodeficiency virus (HIV) conversion from a surgical perspective. Is the risk high or low? That depends on: the rate of HIV in your patients (varies by region); the likelihood of getting injured (varies by specialty); and the HIV conversion rate from the


African crescendo. Statistical aspects of a lethal epidemic [editorial]
Acta Obstet Gynecol Scand. 1994 May;73(5):369-70. Unique Identifier : AIDSLINE MED/94279289
Bergsjo P
Synthesis of a new hydroxyethylene dipeptide isostere Phe psi [CH2CH (OH)]Phe as HIV-1 protease inhibitor.
Chung Kuo Yao Li Hsueh Pao. 1994 Jan;15(1):33-5. Unique Identifier : AIDSLINE MED/94279416
Chen HG; Sawyer TK; Wuts PG; Upjohn Laboratories, Upjohn Company, Kalamazoo, MI 49001.
A new type of pseudopeptide isostere exampled by Phe psi[CH2CH(OH)]Phe was synthesized from phenylalanine. The HIV protease inhibitory activity (IC50) of Noa-His-Phe psi[CH2CH(OH)]Phe-Ile-Amp was 0.8 pmol.L-1.


Effects of tubeimoside-1 on HIV core protein p24 and cytopathogenesis in vitro.
Chung Kuo Yao Li Hsueh Pao. 1994 Mar;15(2):103-6. Unique Identifier : AIDSLINE MED/94279434
Yu LJ; Ma RD; Jiang SB; Department of Biochemistry, Shaanxi Provincial Academy of; Traditional Chinese Medicine and Pharmacology, Xi-an, China.
Tubeimoside-1 (Tub) is a triterpenoid saponin first isolated in China from Bolbostemma paniculatum (Maxim) Franquet, Cucurbitaceae. To find out whether Tub has any anti-infective activity on human immunodeficiency virus (HIV), we tested its effects on HIV core protein p24 (with an E


Relationship between nutritional status and immune function of elderly people.
Age Ageing. 1994 Jan;23(1):49-53. Unique Identifier : AIDSLINE MED/94279525
Roebothan BV; Chandra RK; Department of Biochemistry, Memorial University of Newfoundland,; St John's, Canada.
Thirty-four malnourished subjects between the ages of 61 and 97 years were given appropriate food supplement(s) for a period of 6 consecutive months. They were followed for a subsequent 6 months during which time there was no nutritional intervention. Nutritional assessment and immunological evaluation were performed


Study of T-lymphocyte subpopulation in HBsAg-positive pregnant women.
Acta Virol. 1993 Dec;37(6):459-65. Unique Identifier : AIDSLINE MED/94279538
Kotmire S; Gupta I; Ganguly NK; Koicha M; Postgraduate Institute of Medical Education and Research,; Chandigarh, India.
Pregnancy can alter the immunologic status, especially it can suppress the cell-mediated immunity. The super-imposition of viral infection on the pregnant state leading to further immunosuppression was the subject of this study. 1109 pregnant women were enrolled and screened for hepatitis B surface antigen (HBsAg) car


Symptomatic interleukin-2-induced cholecystopathy in patients with HIV infection.
AJR Am J Roentgenol. 1994 Jul;163(1):117-21. Unique Identifier : AIDSLINE MED/94279552
Powell FC; Spooner KM; Shawker TH; Premkumar A; Thakore KN; Vogel SE; Kovacs JA; Masur H; Feuerstein IM; University of Illinois College of Medicine, Peoria, IL 61656.
OBJECTIVE. This study reports the clinical and radiologic findings in seven patients infected with HIV who had 10 consecutive episodes of symptomatic cholecystopathy induced by infusion of interleukin-2. SUBJECTS AND METHODS. Ten episodes of right upper quadrant pain associated with gallbladder wall thickening were se


Clinical experience with atovaquone: a new drug for treating Pneumocystis carinii pneumonia.
Am J Med Sci. 1994 Jul;308(1):5-8. Unique Identifier : AIDSLINE MED/94279699
Epstein LJ; Mohsenifar Z; Daar ES; Yeh V; Meyer RD; Division of Pulmonary and Critical Care Medicine, Wilford Hall; Medical Center, Lackland Air Force Base, San Antonio, Texas.
Atovaquone is a new hydroxynapthoquinone antiprotozoal agent active against Pneumocystis carinii in vitro and in animal models. The authors report an experience using atovaquone to treat 25 patients with mild to moderate P. carinii pneumonia. Eligible patients were treated for 21 days with 750 mg of atovaquone orally


Tuberculous choroiditis and acquired immunodeficiency syndrome.
Ann Ophthalmol. 1994 Mar-Apr;26(2):50-4. Unique Identifier : AIDSLINE MED/94280095
Perez Blazquez E; Montero Rodriguez M; Mendez Ramos MJ; Hospital 12 de Octubre, Madrid, Spain.
Tuberculosis is a common illness among patients with acquired immunodeficiency syndrome (AIDS), and therefore, choroidal tubercles are expected to be found in these patients. Nevertheless, this association (AIDS-induced choroidal tuberculosis) is infrequently reported in the literature. We report four cases of patient


[Cystic lymphoepithelial lesions in the head and neck area in HIV-infected patients]
Laryngorhinootologie. 1994 Apr;73(4):209-14. Unique Identifier : AIDSLINE MED/94280475
Riederer A; Zietz C; Ihrler S; Vogl T; Klinik und Poliklinik fur Hals-Nasen-Ohren-Kranke, Universitat; Munchen.
Benign lymphoepithelial cysts (BLC) are rare disorders of salivary glands (0.6%). In patients infected by HIV, they are seen more often. In comparison to sporadic BLC, the patients are younger, the diameter of the cysts is up to 5 cm and they are often located bilaterally. At the Department of ENT, Head and Neck Surge


[HIV-associated parotid cysts]
Laryngorhinootologie. 1994 Apr;73(4):215-8. Unique Identifier : AIDSLINE MED/94280476
Rosanowski F; Walther EK; Rockstroh J; Huck P; Oldenburg J; Universitats-Hals-Nasen-Ohren-Klinik Bonn.
20 seropositive HIV patients were examined for the detection of parotid cysts by means of B-mode sonography. In three cases bilateral cysts were found, in three cases unilateral. Only one patient showed clinical symptoms with a bilateral and painless parotideal mass. The cysts were 0.32 to 3.8 cm in diameter. No corre


[Primary clinical manifestation of tuberculosis as an incidental finding in the head and neck area]
Laryngorhinootologie. 1994 Apr;73(4):222-6. Unique Identifier : AIDSLINE MED/94280478
Issing PR; Kempf HG; Ruck P; Lenarz T; Medizinische Hochschule Hannover, Klinik fur HNO-Heikunde.
Between 1988 and 1992 12 patients were seen who had findings leading subsequently to the diagnosis of tuberculosis. The average age was 50 with a range from 22 to 88 years. Women outnumbered the male by 10 to 2 cases. The number of German patients equalled that of foreign patients. Tuberculosis was mainly localised in


A spontaneous point mutation in the human T-cell leukemia virus type 1 pX gene leads to expression of a novel doubly spliced pX-mRNA that encodes a 25-kD, amino-terminal deleted rex protein.
DNA Cell Biol. 1994 Apr;13(4):353-64. Unique Identifier : AIDSLINE GENBANK/D13005
Orita S; Kobayashi H; Saiga A; Kubota R; Osame M; Igarashi H; Shionogi Institute for Medical Science, Osaka, Japan.
Primary RNA transcripts of the human T-cell leukemia virus type 1 (HTLV-1) are processed into mature mRNA by a complex series of splicing events. In this paper, we report the finding of a novel doubly spliced pX mRNA in two out of eight HTLV-1-infected cell lines and in one out of 13 peripheral blood mononuclear cells


Challenges for the development of female-controlled vaginal microbicides [editorial]
AIDS. 1994 Jan;8(1):1-9. Unique Identifier : AIDSLINE MED/94280682
Elias CJ; Heise LL
Dominant situational determinants of sexual risk behaviour in gay men.
AIDS. 1994 Jan;8(1):101-5. Unique Identifier : AIDSLINE MED/94280683
Kelaher M; Ross MW; Rohrsheim R; Drury M; Clarkson A; National Drug and Alcohol Research Center, Sydney, Australia.
OBJECTIVE: To examine the interplay between situational, social and psychological factors in gay men s decisions about HIV risk behaviour, using multiple hypothetical situations. METHOD: The sample included 79 gay men from Sydney recruited through flyers, press advertisements or personal contact at gay venues. Subject


Current status of prophylaxis for opportunistic infections in HIV-infected patients [editorial]
AIDS. 1994 Jan;8(1):11-20. Unique Identifier : AIDSLINE MED/94280685
Decker CF; Masur H
Desire to treat HIV-infected patients: similarities and differences across health-care professions.
AIDS. 1994 Jan;8(1):117-21. Unique Identifier : AIDSLINE MED/94280686
Weyant RJ; Bennett ME; Simon M; Palaisa J; University of Pittsburgh School of Dental Medicine, Department of; Public Health and Community Dentistry, PA 15261.
OBJECTIVES: To determine attitudinal predictors of health-care providers willingness to treat HIV-infected patients. We also tested the hypothesis that differences between dental and medical students in their expressed desire to treat HIV-infected patients result from differences in their clinical exposure to bloodbo


Time from safer to unsafe sexual behaviour among homosexual men.
AIDS. 1994 Jan;8(1):123-6. Unique Identifier : AIDSLINE MED/94280687
de Wit JB; van Griensven GJ; Utrecht University, Department of Gay and Lesbian Studies, The; Netherlands.
OBJECTIVE: To study relapse into unsafe sex among homosexual men using a novel method. DESIGN: Time from safer to unsafe sexual behaviour was analysed using Kaplan-Meier procedures. Cox proportional hazard analysis was performed to quantify the relation between duration of safer sex and several covariates. SUBJECTS: S


Measuring the impact of HIV/AIDS in Africa [editorial]
AIDS. 1994 Jan;8(1):127-8. Unique Identifier : AIDSLINE MED/94280688
De Cock KM
Vertical transmission of HIV: detection of proviral DNA in placental trophoblast [letter]
AIDS. 1994 Jan;8(1):129-30. Unique Identifier : AIDSLINE MED/94280689
Zachar V; Thomas RA; Jones T; Goustin AS
Normal triglyceride levels in early HIV-1 infection [letter; comment]
AIDS. 1994 Jan;8(1):131-2. Unique Identifier : AIDSLINE MED/94280691
Baum MK; Shor-Posner G; Lu Y
Systematic screening for HIV infection--a reply [letter; comment]
AIDS. 1994 Jan;8(1):132-3. Unique Identifier : AIDSLINE MED/94280692
Monteith SK
HIV-1 prevalence among Israeli and Palestinian blood donors [letter]
AIDS. 1994 Jan;8(1):133-4. Unique Identifier : AIDSLINE MED/94280693
Maayan S; Shinar E; Aefani M; Soughayer M; Alkhoudary R; Barshany S; Manny N
Conjunctival microvasculopathy and Kaposi's sarcoma in patients with AIDS [letter]
AIDS. 1994 Jan;8(1):134-5. Unique Identifier : AIDSLINE MED/94280694
Baumann S; Geier SA; Thoma-Gerber E; Bogner JR; Gurtler L; Klauss V; Goebel FD
The use of the flarephotometry in the detection of cytomegalic virus retinitis in AIDS patients [letter]
AIDS. 1994 Jan;8(1):135-6. Unique Identifier : AIDSLINE MED/94280695
Nussenblatt RB; De Smet M; Podgor M; Lane C; Polis M; Pizzo P; Perry C; Belfort R Jr
Corticosteroid therapy for AIDS patients with Mycobacterium avium-intracellulare infection [letter]
AIDS. 1994 Jan;8(1):136-8. Unique Identifier : AIDSLINE MED/94280696
Steven N; Pithie A; Wood M; Innes J
Splenectomy in patients with AIDS [letter; comment]
AIDS. 1994 Jan;8(1):138. Unique Identifier : AIDSLINE MED/94280697
Levin M
Passage to India: the HIV blockade on Kenyan students [letter]
AIDS. 1994 Jan;8(1):138-9. Unique Identifier : AIDSLINE MED/94280698
Songok EM; Oogo SA; Mutura CW; Muniu EM; Koimett EC; Libondo DL; Tukei PM; Koech DK
Premature removal of condoms by young men in Abidjan, Cote d'Ivoire: an example of an AIDS prevention dilemma [letter]
AIDS. 1994 Jan;8(1):140. Unique Identifier : AIDSLINE MED/94280699
Deniaud F
Molecular phylogeny of part of the env gene of HIV-1 strains isolated in Cote d'Ivoire.
AIDS. 1994 Jan;8(1):21-6. Unique Identifier : AIDSLINE GENBANK/X72053
Janssens W; Heyndrickx L; Van de Peer Y; Bouckaert A; Fransen K; Motte J; Gershy-Damet GM; Peeters M; Piot P; van der Groen G; Department of Infection and Immunity, University of Antwerp,; Belgium.
OBJECTIVES: To examine the genetic variation of HIV-1 isolates in Abidjan, Cote d Ivoire , and to determine the extent to which phylogenetic trees based on sequence information of part of the env gene containing the principal neutralizing domain are representative for documenti


Progressive multifocal leukoencephalopathy diagnosed by amplification of JC virus-specific DNA from cerebrospinal fluid.
AIDS. 1994 Jan;8(1):49-57. Unique Identifier : AIDSLINE MED/94280704
Weber T; Turner RW; Frye S; Luke W; Kretzschmar HA; Luer W; Hunsmann G; Neurologische Klinik und Poliklinik, Georg-August-Universitat; Gottingen, Germany.
OBJECTIVE: To study the diagnostic sensitivity and specificity of polymerase chain reaction (PCR) for the non-invasive diagnosis of progressive multifocal leukoencephalopathy (PML) in HIV-1-infected individuals. DESIGN: Retrospective analysis of stored cerebrospinal fluid (CSF) samples by PCR of HIV-1-infected patient


A phase I study of subcutaneous recombinant interleukin-2 in patients with advanced HIV disease while on zidovudine.
AIDS. 1994 Jan;8(1):59-66. Unique Identifier : AIDSLINE MED/94280705
McMahon DK; Armstrong JA; Huang XL; Rinaldo CR Jr; Gupta P; Whiteside TL; Pazin GJ; Tripoli C; Ho M; Department of Infectious Diseases and Microbiology, Graduate; School of Public Health, University of Pittsburgh, Pennsylvania; 15261.
OBJECTIVE: A Phase I study of subcutaneous recombinant interleukin-2 (rIL-2). DESIGN: Sixteen patients with advanced HIV infection receiving 600-1200 mg zidovudine per day were divided into three groups, which received sequentially 0.2 x 10(6), 0.7 x 10(6) or 2 x 10(6) units/m2 per day of rIL-2 subcutaneously 5 consec


Cerebrospinal fluid dopamine in HIV-1 infection.
AIDS. 1994 Jan;8(1):67-71. Unique Identifier : AIDSLINE MED/94280706
Berger JR; Kumar M; Kumar A; Fernandez JB; Levin B; Department of Neurology, University of Miami School of Medicine,; Florida 33151.
BACKGROUND: Increasing evidence suggests significant involvement of the basal ganglia in patients with HIV-1 infection. OBJECTIVE: To study the effect of HIV-1 infection on cerebrospinal fluid (CSF) dopamine levels. DESIGN: CSF dopamine levels were measured by high-performance liquid chromatography. SETTING: A univers


Time from HIV seroconversion to oral candidiasis or hairy leukoplakia among homosexual and bisexual men enrolled in three prospective cohorts.
AIDS. 1994 Jan;8(1):73-9. Unique Identifier : AIDSLINE MED/94280707
Lifson AR; Hilton JF; Westenhouse JL; Canchola AJ; Samuel MC; Katz MH; Buchbinder SP; Hessol NA; Osmond DH; Shiboski S; et al; Department of Epidemiology and Biostatistics, University of; California, San Francisco.
OBJECTIVES: We evaluated time from HIV seroconversion to diagnosis of two common oral lesions associated with HIV infection and disease progression. DESIGN: Oral examinations were performed on homosexual and bisexual men enrolled in prospective cohorts. SETTING: Homosexual and bisexual men were followed in three epide


Risk factors for HIV-1 infection in adults in a rural Ugandan community: a population study.
AIDS. 1994 Jan;8(1):81-6. Unique Identifier : AIDSLINE MED/94280708
Nunn AJ; Kengeya-Kayondo JF; Malamba SS; Seeley JA; Mulder DW; Medical Research Council Programme on AIDS in Uganda, Uganda; Virus Research Institute, Entebbe.
OBJECTIVE: To determine sociodemographic risk factors associated with HIV-1 infection in a rural Ugandan population. DESIGN: A population-based survey. METHODS: All adult residents (aged > or = 13 years) in a cluster of 15 neighbouring villages of the Masaka District of south-west Uganda were invited to participate in


HIV-1 incidence and HIV-1-associated mortality in a rural Ugandan population cohort.
AIDS. 1994 Jan;8(1):87-92. Unique Identifier : AIDSLINE MED/94280709
Mulder DW; Nunn AJ; Wagner HU; Kamali A; Kengeya-Kayondo JF; Medical Research Council Programme on AIDS in Uganda, Uganda; Virus Research Institute, Entebbe.
OBJECTIVE: To determine the incidence of HIV-1 infection and HIV-1-associated mortality in a rural Ugandan population. DESIGN: A prospective cohort study. METHODS: A cohort consisting of the population (de jure census 9820) of a cluster of 15 villages in Masaka District, south-west Uganda was enrolled between 1989 and


Sexual behavior, sexually transmitted diseases, male circumcision and risk of HIV infection among women in Nairobi, Kenya.
AIDS. 1994 Jan;8(1):93-9. Unique Identifier : AIDSLINE MED/94280710
Hunter DJ; Maggwa BN; Mati JK; Tukei PM; Mbugua S; Department of Epidemiology, Harvard School of Public Health,; Boston, MA 02115.
OBJECTIVE: To study risk factors for HIV infection among women in Nairobi, Kenya , as the epidemic moves beyond high-risk groups. DESIGN: A cross-sectional case-control study among women attending two peri-urban family planning clinics. METHODS: A total of 4404 women were enrolled af


Treating depression in HIV-positive patients [editorial]
AIDS. 1994 Apr;8(4):403-12. Unique Identifier : AIDSLINE MED/94280711
Markowitz JC; Rabkin JG; Perry SW
Peptide serology for analysis of the inter- and intra-individual variation in the HIV-1 V3 domain.
AIDS. 1994 Apr;8(4):413-21. Unique Identifier : AIDSLINE MED/94280712
Jansson M; Wahren B; Albert J; Scarlatti G; Franzen L; Kataaha PK; Katabira E; Mubiro F; Wigzell H; Rossi P; Department of Immunology, Karolinska Institute, Stockholm,; Sweden.
OBJECTIVE: To investigate whether the specificity of antibody responses to the gp120 V3 domain in HIV-1-infected individuals is related to the variability of this region. METHODS: Sera from a cohort of 22 HIV-1-infected Ugandans were tested against peptides derived from each individual s autologous proviral V3 apex se


Enhancement of HIV-1 replication in peripheral blood mononuclear cells by Cryptococcus neoformans is monocyte-dependent but tumour necrosis factor-independent.
AIDS. 1994 Apr;8(4):423-9. Unique Identifier : AIDSLINE MED/94280713
Orendi JM; Nottet HS; Visser MR; Verheul AF; Snippe H; Verhoef J; Department of Clinical Microbiology, University Hospital Utrecht,; The Netherlands.
OBJECTIVE: To investigate the possible role of Cryptococcus neoformans in HIV-1 pathogenesis. DESIGN: An in vitro system was developed to study HIV-1 replication in freshly HIV-1-infected peripheral blood mononuclear cells (PBMC) incubated with whole azide-killed C. neoformans. METHODS: Human PBMC or peripheral blood


Lymphocyte activation in HIV-1 infection. II. Functional defects of CD28- T cells.
AIDS. 1994 Apr;8(4):431-41. Unique Identifier : AIDSLINE MED/94280714
Borthwick NJ; Bofill M; Gombert WM; Akbar AN; Medina E; Sagawa K; Lipman MC; Johnson MA; Janossy G; Department of Clinical Immunology, Royal Free Hospital and School; of Medicine, London, UK.
OBJECTIVES AND DESIGN: The expression of the accessory molecule CD28 was compared in various populations of T and natural killer (NK) cells from HIV-1-negative and HIV-1-positive individuals and correlated with activation using mitogens in vitro. METHODS: Multiparameter flow cytometric analysis using combinations of C


Lack of evidence for a superantigen in lymphocytes from HIV-discordant monozygotic twins.
AIDS. 1994 Apr;8(4):443-9. Unique Identifier : AIDSLINE MED/94280715
Nisini R; Aiuti A; Matricardi PM; Fattorossi A; Ferlini C; Biselli R; Mezzaroma I; Pinter E; D'Amelio R; Dipartimento di Biopatologia Umana, Universita La Sapienza di; Roma, Italy.
OBJECTIVE: An HIV-associated superantigen (SAg) has been hypothesized. Here we test whether an SAg is functionally detectable in peripheral blood mononuclear cells (PBMC) from monozygotic twins discordant for HIV infection. DESIGN AND METHODS: The V beta selective T-cell depletion found in minor lymphocyte stimulation


Phase II dose-ranging trial of foscarnet salvage therapy for cytomegalovirus retinitis in AIDS patients intolerant of or resistant to ganciclovir (ACTG protocol 093). AIDS Clinical Trials Group of the National Institute of Allergy and Infectious Diseases.
AIDS. 1994 Apr;8(4):451-9. Unique Identifier : AIDSLINE MED/94280716
Jacobson MA; Wulfsohn M; Feinberg JE; Davis R; Power M; Owens S; Causey D; Heath-Chiozzi ME; Murphy RL; Cheung TW; et al; Department of Medicine, University of California, San Francisco.
OBJECTIVE: To document response to foscarnet salvage therapy in patients with cytomegalovirus ( CMV ) retinitis who are intolerant of or resistant to ganciclovir. METHODS: Patients with AIDS and CMV retinitis who had documented


Cytomegalovirus colitis in HIV-1-infected patients: a prospective research in 55 patients.
AIDS. 1994 Apr;8(4):461-7. Unique Identifier : AIDSLINE MED/94280717
Mentec H; Leport C; Leport J; Marche C; Harzic M; Vilde JL; Department of Infectious and Tropical Diseases, Claude Bernard; Hospital, Paris, France.
OBJECTIVE: To determine criteria for the diagnosis of cytomegalovirus ( CMV ) colitis and to analyse stages of the course and prognosis of CMV colonic involvement in HIV-1-infected patients. DESIGN: Prospective search for CMV c


Purified protein derivative tuberculin and delayed-type hypersensitivity skin testing in migrant farm workers at risk for tuberculosis and HIV coinfection.
AIDS. 1994 Apr;8(4):477-81. Unique Identifier : AIDSLINE MED/94280719
Villarino ME; Geiter LJ; Schulte JM; Castro KG; Division of Tuberculosis Elimination, Centers for Disease Control; and Prevention, Atlanta, Georgia 30333.
OBJECTIVE: To assess the joint use of purified protein derivative (PPD) and delayed-type hypersensitivity (DTH) antigens in screening individuals of unknown HIV serostatus for tuberculosis (TB) preventive therapy eligibility. DESIGN: Population-based survey. METHODS: A group of migrant farm workers were screened for H


Toxoplasma gondii infection in advanced HIV infection.
AIDS. 1994 Apr;8(4):483-7. Unique Identifier : AIDSLINE MED/94280720
Oksenhendler E; Charreau I; Tournerie C; Azihary M; Carbon C; Aboulker JP; INSERM SC10, Villejuif, France.
OBJECTIVE: To study Toxoplasma encephalitis (TE) in advanced HIV infection, including predictive factors, possible prophylactic regimens and impact on survival. DESIGN: Epidemiological analysis of data collected prospectively during the Alpha study, a double-blind, randomized clinical trial, comparing two doses of did


Zidovudine therapy and HIV encephalitis: a 10-year neuropathological survey.
AIDS. 1994 Apr;8(4):489-93. Unique Identifier : AIDSLINE MED/94280721
Gray F; Belec L; Keohane C; De Truchis P; Clair B; Durigon M; Sobel A; Gherardi R; Laboratoire d'Anatomie Pathologique (Neuropathologie), Hopital; Raymond Poincare, Garches, France.
OBJECTIVE: To assess the effect of zidovudine on productive HIV infection of the brain. DESIGN: To correlate the incidence of HIV-specific neuropathology with zidovudine therapy. PATIENTS: We examined 192 AIDS cases neuropathologically; 97 had never been treated with zidovudine, 72 had received zidovudine for over 3 m


Altered cortical blood flow in HIV-seropositive individuals with and without dementia: a single photon emission computed tomography study.
AIDS. 1994 Apr;8(4):495-9. Unique Identifier : AIDSLINE MED/94280722
Harris GJ; Pearlson GD; McArthur JC; Zeger S; LaFrance ND; Department of Psychiatry, Tufts University School of Medicine/New; England Medical Center, Boston, Massachusetts.
OBJECTIVE: To quantitatively demonstrate the pattern of cerebral perfusion abnormalities in HIV-1-infected individuals described as patchiness or inhomogeneity in previous qualitative emission tomographic imaging studies. DESIGN: We aimed to create a quantitative measure of inhomogeneity in HIV-infected individuals.


Diet-induced thermogenesis in HIV infection.
AIDS. 1994 Apr;8(4):501-4. Unique Identifier : AIDSLINE MED/94280723
Poizot-Martin I; Benourine K; Philibert P; Boulet JM; Badetti C; Tramier M; Vollot F; Dalmas AM; Manelli JC; Gastaut JA; Departement d'Hematologie, Institut Paoli-Calmettes, Marseille,; France.
OBJECTIVE: To assess whether postprandial dietary thermogenesis contributes to weight loss during HIV infection. METHODS: The thermogenic response to a test meal (15 kcal/kg) was evaluated with indirect calorimetry in 16 HIV-infected patients in a stable condition and compared with a control group. Patients were compa


The incidence of HIV infection among men in the United States Army Reserve Components, 1985-1991.
AIDS. 1994 Apr;8(4):505-11. Unique Identifier : AIDSLINE MED/94280724
Cowan DN; Brundage JF; Pomerantz RS; SRA Technologies, Inc., Falls Church, VA 22042.
OBJECTIVE: To evaluate the incidence of HIV infection among men in the Army Reserve Components (RC) in the United States . METHODS: A prospective follow-up evaluating HIV seroconversions among men in the RC. Men who were initially seronegative were followed over time and periodically re


The pattern of diagnosed HIV infection in Australia, 1984-1992.
AIDS. 1994 Apr;8(4):513-9. Unique Identifier : AIDSLINE MED/94280725
McDonald AM; Crofts N; Blumer CE; Gertig DM; Patten JJ; Roberts M; Davey T; Mullins SE; Chuah JC; Bailey KA; et al; National Centre in HIV Epidemiology and Clinical Research,; Sydney, New South Wales, Australia.
OBJECTIVE: To describe the pattern of newly diagnosed HIV infection in Australia , between 1984 and 1992. METHODS: State and Territory health authorities reported cases of newly diagnosed HIV infection to the national HIV surveillance centre. Information sought on each case inclu


Edinburgh drug users: are they injecting and sharing less?
AIDS. 1994 Apr;8(4):521-8. Unique Identifier : AIDSLINE MED/94280726
Peters AD; Reid MM; Griffin SG; Community Drug Problems Service, Lothian Health Board, Edinburgh,; UK.
OBJECTIVE: To describe epidemiological trends in injecting and equipment sharing among a sample drawn from a drug-using population with a high rate of HIV infection. DESIGN: A structured interview was administered prior to treatment to cross-sectional samples of drug users over the period 1988-1991. Reports of injecti


Was the 1988 HIV epidemic among Bangkok's injecting drug users a common source outbreak?
AIDS. 1994 Apr;8(4):529-32. Unique Identifier : AIDSLINE MED/94280727
Wright NH; Vanichseni S; Akarasewi P; Wasi C; Choopanya K; UMD-Robert Wood Johnson Medical School, Piscataway, New Jersey; 08854.
OBJECTIVE: To describe and understand the genesis of the explosive 1988 HIV epidemic among Thai injecting drug users (IDU) in Bangkok. DESIGN: Two cross-sectional HIV seroprevalence sample surveys (SP-1 and SP-2) of drug users, including IDU at various stages of treatment. SP-1, a 10-week estimate of prevalence, was c


HIV-1 infection among lower class commercial sex workers in Chiang Mai, Thailand.
AIDS. 1994 Apr;8(4):533-7. Unique Identifier : AIDSLINE MED/94280728
Celentano DD; Akarasewi P; Sussman L; Suprasert S; Matanasarawoot A; Wright NH; Theetranont C; Nelson KE; Johns Hopkins University School of Hygiene and Public Health,; Baltimore, Maryland 21205.
OBJECTIVE: To determine risk factors for HIV-1 infection in female commercial sex workers (CSW) in northern Thailand . METHODS: A cross-sectional survey of female CSW from 11 sex establishments frequented by military conscripts that included an interview and serological testing fo


Modeling the impact and cost-effectiveness of HIV prevention efforts.
AIDS. 1994 Apr;8(4):539-48. Unique Identifier : AIDSLINE MED/94280729
Rowley JT; Anderson RM; Biology Department, Imperial College of Science, Technology and; Medicine, London, UK.
OBJECTIVES: This study explores how mathematical models can be used to examine the relationship between the effectiveness and costs of different prevention strategies. The analysis, based on a model designed to simulate the spread of HIV in sub-Saharan Africa, illustrates how the impact and relative cost-effectiveness


High rate of HIV seroconversion among patients attending urban sexually transmitted disease clinics.
AIDS. 1994 Apr;8(4):549-53. Unique Identifier : AIDSLINE MED/94280730
Otten MW Jr; Zaidi AA; Peterman TA; Rolfs RT; Witte JJ; Division of STD/HIV Prevention, Centers for Disease Control and; Prevention, Atlanta, Georgia 30333.
OBJECTIVE: To study rates of documented HIV seroconversion and syphilis as a cofactor for seroconversion in sexually transmitted disease (STD) clinics. In the main clinic the HIV seroprevalence rate was 12% and most infections had been shown to be acquired by heterosexual contact. METHODS: We analyzed computer records


Cryptosporidiosis of the nasal mucosa in a patient with AIDS [letter]
AIDS. 1994 Apr;8(4):555-6. Unique Identifier : AIDSLINE MED/94280731
Giang TT; Pollack G; Kotler DP
Insulin-dependent diabetes in AIDS [letter]
AIDS. 1994 Apr;8(4):556-7. Unique Identifier : AIDSLINE MED/94280732
Ioannidis JP; Iacoviello VR; Samore MH
Clostridium difficile-associated diarrhoea in HIV-infected patients [letter; comment]
AIDS. 1994 Apr;8(4):557-8. Unique Identifier : AIDSLINE MED/94280733
McBride MO; Horner PJ; Coker RJ; Harris JR
Diffuse cutaneous leishmaniasis with visceral dissemination in an AIDS patient in Guadeloupe, West Indies [letter]
AIDS. 1994 Apr;8(4):559-60. Unique Identifier : AIDSLINE MED/94280735
Cnudde F; Raccurt C; Boulard F; Terron-Aboud B; Nicolas M; Juminer B
Complementary therapies used by people with HIV infection [letter]
AIDS. 1994 Apr;8(4):561. Unique Identifier : AIDSLINE MED/94280736
Barton SE; Davies S; Schroeder K; Arthur G; Gazzard BG
Hypomagnesaemia associated with pentamidine therapy [letter]
AIDS. 1994 Apr;8(4):561-3. Unique Identifier : AIDSLINE MED/94280737
Nielsen H
Incidence and prophylaxis of non-tuberculous mycobacteriosis in HIV-infected patients [letter]
AIDS. 1994 Apr;8(4):563-4. Unique Identifier : AIDSLINE MED/94280738
Opravil M; Hachler I; Luthy R
Risk of HIV infection and AIDS in women and girls with coagulation disorders [letter]
AIDS. 1994 Apr;8(4):564-5. Unique Identifier : AIDSLINE MED/94280739
Goedert JJ; Garvey L; Hilgartner MW; Blatt PM; Aledort LM; Cohen AR; Kessler CM; White GC; Mandalaki T; Cook RA; et al
DoH distributes HIV/AIDS packs for primary carers [news]
Nurs Stand. 1994 Apr 27-May 3;8(31):15. Unique Identifier : AIDSLINE MED/94280975
Rifampicin resistance may threaten therapy [news]
Nurs Stand. 1994 Apr 27-May 3;8(31):17. Unique Identifier : AIDSLINE MED/94280976
Plans for sex education attacked [news]
Nurs Stand. 1994 Apr 27-May 3;8(31):7. Unique Identifier : AIDSLINE MED/94280988
Variation in AIDS survival in Europe [news]
Nurs Stand. 1994 May 11-17;8(33):14. Unique Identifier : AIDSLINE MED/94280989
Expression of fos proto-oncogene product by monoclonal antibody FO-120 in smouldering adult T-cell leukaemia (ATL).
Br J Haematol. 1994 Jan;86(1):193-4. Unique Identifier : AIDSLINE MED/94281077
Iwahashi M; Otsuka M; Shimotakahara S; Uozumi K; Hanada S; Arima T; Matsumoto M; Second Department of Internal Medicine, Oita Medical University,; Japan.
We investigated the expression of c-fos gene product in peripheral blood mononuclear cells of patients with smouldering adult T-cell leukaemia (ATL) and healthy human T-lymphotropic virus type-I (HTLV-I) carriers by an immunofluorescence assay, using a mouse monoclonal antibody (FO-120) specific for fos gene product.


Etiology, epidemiology, risk factors, and public health issues of melanoma.
Curr Opin Oncol. 1994 Mar;6(2):179-87. Unique Identifier : AIDSLINE MED/94281281
Elwood JM; Koh HK; Department of Preventive and Social Medicine, University of; Otago, Otago Medical School, Dunedin, New Zealand.
Evidence from several countries suggests that the long-continued increase in melanoma-related mortality is slowing or has ceased. In some countries, decreasing rates are now seen particularly in women. These trends are probably due to successful primary prevention and early diagnosis. However, incidence continues to i


[Incidence of lymphoid neoplasms in patients with HIV infection]
Enferm Infecc Microbiol Clin. 1994 Feb;12(2):86-9. Unique Identifier : AIDSLINE MED/94281303
Olivera M; Teira R; Munoz J; Olabarria I; Zubero Z; Cisterna R; Santamaria JM; Servicio de Medicina Interna, Hospital Civil de Bilbao.
BACKGROUND: The incidence, histologic type and clinical characteristics of the lymphoid neoplasms found in patients with HIV infection may be influenced by environmental factors. These characteristics were herewith investigated in the authors medium. METHODS: The medical records of the patients in whom lymphoma was di


[HIV vaccines: difficulties and perspectives (editorial)]
Enferm Infecc Microbiol Clin. 1994 Mar;12(3):119-21. Unique Identifier : AIDSLINE MED/94281306
Casabona J
[Therapeutic alternatives for cases of cerebral toxoplasmosis in patients with AIDS: clarithromycin and atovaquone]
Enferm Infecc Microbiol Clin. 1994 Mar;12(3):137-40. Unique Identifier : AIDSLINE MED/94281310
Guelar A; Miro JM; Mallolas J; Zamora L; Cardenal C; Gatell JM; Soriano E; Servicio de Infecciones, Hospital Clinic i Provincial,; Barcelona.
BACKGROUND: Cerebral toxoplasmosis is the most common opportunistic infection of the central nervous system in AIDS patients. Its rate varies between 3-40% according to the prevalence of toxoplasmosis in the different geographic areas. Conventional treatments used for this pathology are: sulphadiacin or clindamycin pl


[Splenic abscesses caused by Mycobacterium tuberculosis in AIDS]
Enferm Infecc Microbiol Clin. 1994 Mar;12(3):146-9. Unique Identifier : AIDSLINE MED/94281312
Salazar A; Carratala J; Santin M; Meco F; Rufi G; Servicio de Enfermedades Infecciosas, Hospital de; Bellvitge-Princeps d'Espanya, Universidad de Barcelona.
BACKGROUND: Up to 70% of the patients with tuberculosis and HIV infection develop extrapulmonary disease. Abdominal participation is generally of the lymph node type with splenic tuberculosis being rare. METHODS: Two cases of splenic tuberculosis from a series of 557 patients diagnosed with AIDS in a general hospital


[Tuberculous meningitis caused by resistant microorganisms. Therapeuticfailure in 2 patients with HIV infection and disseminated tuberculosis (see comments)]
Enferm Infecc Microbiol Clin. 1994 Mar;12(3):150-3. Unique Identifier : AIDSLINE MED/94281313
Fortun J; Gomez-Mampaso E; Navas E; Hermida JM; Antela A; Guerrero A; Seccion de Enfermedades Infecciosas, Hospital Ramon y Cajal,; Madrid.
BACKGROUND: Tuberculosis in HIV infected patients does not carry a worse therapeutic response rate. Treatment failure is usually due to incomplete schedule, with development of acquired resistance. Two patients with HIV infection and disseminated tuberculosis who developed fatal meningitis are presented. METHODS: In v


[Treatment and primary and secondary prevention of cerebral toxoplasmosis in patients with HIV infection]
Enferm Infecc Microbiol Clin. 1994 Mar;12(3):158-63. Unique Identifier : AIDSLINE MED/94281315
Podzamczer D; Servicio de Enfermedades Infecciosas, Hospital de; Bellvitge-Princeps d'Espanya, Barcelona.
[Thumb-nail lesion in a patient with AIDS]
Enferm Infecc Microbiol Clin. 1994 Mar;12(3):167-8. Unique Identifier : AIDSLINE MED/94281317
Belinchon I; Ramos JM; Unidad de Dermatologia, Hospital Universitari Sant Joan,; Alicante.
[Bacteremia caused by quinolone-resistant Campylobacter jejuni in a patient with HIV infection (letter)]
Enferm Infecc Microbiol Clin. 1994 Mar;12(3):170-2. Unique Identifier : AIDSLINE MED/94281320
Elcuaz R; Lluch-Perales JF; Gomez E; Suarez J; Hernandez M; LaFarga B
[Cryptococcal gastrointestinal ulcerations in an HIV-positive patient (letter)]
Enferm Infecc Microbiol Clin. 1994 Mar;12(3):176-7. Unique Identifier : AIDSLINE MED/94281324
de Otero J; Flor A; Cortes E; Cuenca A; de Torres I; Capdevilea JA
Evaluation of neurosyphilis in human immunodeficiency virus-infected individuals.
Clin Infect Dis. 1994 Mar;18(3):288-94. Unique Identifier : AIDSLINE MED/94281403
Tomberlin MG; Holtom PD; Owens JL; Larsen RA; Department of Medicine, Los Angeles County-University of Southern; California Medical Center.
The diagnosis of neurosyphilis in patients infected with the human immunodeficiency virus (HIV) remains problematic. We examined the use of the Treponema pallidum hemagglutination (TPHA) index and quantitative tests of CSF by means of microhemagglutination-T. pallidum for diagnosis of neurosyphilis in 58 HIV-infected


Diagnosing neurosyphilis [editorial]
Clin Infect Dis. 1994 Mar;18(3):295-7. Unique Identifier : AIDSLINE MED/94281404
Hook EW 3rd
Effect of corticosteroids on the incidence of adverse cutaneous reactions to trimethoprim-sulfamethoxazole during treatment of AIDS-associated Pneumocystis carinii pneumonia.
Clin Infect Dis. 1994 Mar;18(3):319-23. Unique Identifier : AIDSLINE MED/94281409
Caumes E; Roudier C; Rogeaux O; Bricaire F; Gentilini M; Departement des Maladies Infectieuses, Parasitaires, Tropicales,; et Sante Publique, Hopital Pitie-Salpetriere, Paris, France.
We retrospectively studied all courses of treatment with trimethoprim-sulfamethoxazole (TMP-SMZ) alone and with adjuvant corticosteroids for AIDS-associated Pneumocystis carinii pneumonia. The corticosteroids were administered for 8-21 days (mean, 14 days) because of hypoxemia. We evaluated the influence of corticoste


Clinical aspects of the interactions between human immunodeficiency virus and the hepatotropic viruses.
Clin Infect Dis. 1994 Mar;18(3):339-47. Unique Identifier : AIDSLINE MED/94281412
Horvath J; Raffanti SP; Division of Infectious Diseases, Vanderbilt University School of; Medicine, Nashville, Tennessee 37232-2605.
The hepatitis viruses A through D are prevalent among patients at risk for human immunodeficiency virus (HIV) infection. The courses of hepatitis B, C, and D are modified by HIV infection. With hepatitis B, increased carriage rates, increased viral replication, and milder liver injury are seen. The degree of HIV-induc


Nocardiosis in 30 patients with advanced human immunodeficiency virus infection: clinical features and outcome.
Clin Infect Dis. 1994 Mar;18(3):348-53. Unique Identifier : AIDSLINE MED/94281413
Uttamchandani RB; Daikos GL; Reyes RR; Fischl MA; Dickinson GM; Yamaguchi E; Kramer MR; Department of Medicine, University of Miami School of Medicine,; Florida.
A total of 30 patients (aged 6-56 years) with nocardiosis and infection due to human immunodeficiency virus type 1 (HIV-1) were identified in our institution between January 1985 and June 1989. Eighteen patients had an AIDS-defining illness before or concurrently with nocardiosis. The mean CD4 lymphocyte count was 109


Relationship between human immunodeficiency virus infection and salmonellosis in 20- to 59-year-old residents of New York City.
Clin Infect Dis. 1994 Mar;18(3):358-63. Unique Identifier : AIDSLINE MED/94281415
Gruenewald R; Blum S; Chan J; Enteric Bacteriology Laboratory, New York City Department of; Health, New York 10016.
Among 20- to 59-year-old residents of New York City who have septicemia, gastroenteritis, urinary tract infection, and multiple site infections due to Salmonella, those listed in the New York City AIDS Registry were highly overrepresented. Among the patients listed in the registry, males outnumbered females by 4:1 (se


Clinical epidemiological study of 171 cases of cryptococcosis.
Clin Infect Dis. 1994 Mar;18(3):369-80. Unique Identifier : AIDSLINE MED/94281417
Rozenbaum R; Goncalves AJ; Servico de Doencas Infecciosas e Parasitarias, Hospital dos; Servidores do Estado do Rio de Janeiro, Brazil.
We retrospectively studied 171 patients with cryptococcosis who were divided into three groups according to their associated predisposing conditions (if any): group 1 comprised nonimmunosuppressed patients, group 2 comprised patients with AIDS, and group 3 comprised those patients with other conditions and/or who were


Mycobacterium kansasii among patients infected with human immunodeficiency virus in Kansas City. Kansas City AIDS Research Consortium.
Clin Infect Dis. 1994 Mar;18(3):395-400. Unique Identifier : AIDSLINE MED/94281421
Bamberger DM; Driks MR; Gupta MR; O'Connor MC; Jost PM; Neihart RE; McKinsey DS; Moore LA; University of Missouri-Kansas City School of Medicine, Kansas; City, Missouri.
Previous reports of infection due to Mycobacterium kansasii among patients infected with human immunodeficiency virus (HIV) have conflicted with regard to the significance of the isolate; the clinical, radiographic, and laboratory features of the disease; and the response to therapy. To clarify the spectrum of M. kans


Paromomycin: an effective treatment for cryptosporidial diarrhea in patients with AIDS.
Clin Infect Dis. 1994 Mar;18(3):447-9. Unique Identifier : AIDSLINE MED/94281432
Bissuel F; Cotte L; Rabodonirina M; Rougier P; Piens MA; Trepo C; AIDS and Hepatogastroenterology Unit, Hopital de l'Hotel-Dieu,; Lyon, France.
Cryptosporidiosis is a common cause of diarrhea in patients with AIDS but remains one of the most challenging AIDS-related conditions to treat. We therefore carried out an open, uncontrolled, prospective study to evaluate the efficacy of oral paromomycin for the treatment of chronic diarrhea due to Cryptosporidium in


Toxoplasma-induced cystitis in a patient with AIDS.
Clin Infect Dis. 1994 Mar;18(3):453-4. Unique Identifier : AIDSLINE MED/94281434
Welker Y; Geissmann F; Benali A; Bron J; Molina JM; Decazes JM; Department of Infectious Diseases, Hopital Saint Louis, Paris,; France.
We report a case of cystitis due to Toxoplasma gondii in a patient with AIDS who presented with dysuria and urinary frequency. To our knowledge, this is the first reported case of cystitis due to this organism. Microscopy of bladder specimens revealed inflammatory cystitis, with Toxoplasma cysts disseminated within th


Successful treatment of disseminated Mycobacterium haemophilum infection in a patient with AIDS [letter]
Clin Infect Dis. 1994 Mar;18(3):475-6. Unique Identifier : AIDSLINE MED/94281443
Soubani AO; al-Marri M; Forlenza S
Detection of Pneumocystis carinii in urinary samples from a patient with AIDS despite prophylactic treatment with aerosolized pentamidine [letter]
Clin Infect Dis. 1994 Mar;18(3):477-8. Unique Identifier : AIDSLINE MED/94281445
Contini C; Romani R; Vullo V; Delia S; Sorice F
Serum adenosine deaminase levels in intravenous drug users with and without infection due to human immunodeficiency virus [letter; comment]
Clin Infect Dis. 1994 Mar;18(3):478-9. Unique Identifier : AIDSLINE MED/94281446
Inigo MA; Lopez de Tejada MR; Torres-Tortosa M; Sanchez-Porto A
Pyrimethamine as primary prophylaxis of toxoplasmic encephalitis in patients infected with human immunodeficiency virus: open study [letter]
Clin Infect Dis. 1994 Mar;18(3):479-80. Unique Identifier : AIDSLINE MED/94281447
Bachmeyer C; Gorin I; Deleuze J; Morini JP; Escande JP
[Characteristics and factors associated to the presence of fever in tuberculosis]
An Med Interna. 1994 Mar;11(3):123-5. Unique Identifier : AIDSLINE MED/94281475
Knobel H; Galofre N; Pena MJ; Shaat M; Salvado M; Diez A; Servicio de Medicina Interna, Hospital de la Esperanza,; Barcelona.
The aim of this study was to determine the characteristics and factors associated to the presence of fever in the tuberculous disease. One hundred and three patients were included in the study (29 infected by the HIV, 24 old patients with more than 65 years of age and 50 adults). Fever was present in 59.2% of the pati


[Terminal ileitis due to cryptosporidium and cytomegalovirus in a patient with AIDS]
An Med Interna. 1994 Mar;11(3):139-41. Unique Identifier : AIDSLINE MED/94281480
Gonzalez Anglada MI; Barbado FJ; Arribas JR; Perez G; Casal V; Vazquez JJ; Garcia Viera M; Servicio de Medicina Interna, Hospital La Paz, Universidad; Autonoma, Madrid.
Terminal patients with infection by the Human Immunodeficiency Virus (HIV), gastrointestinal affection is frequently observed, caused by many etiological agents. However, the affection of the terminal ileon is and generally associated to cytomegalovirus (


[Malignant histiocytoma in a patient infected with the human immunodeficiency virus (letter) (see comments)]
An Med Interna. 1994 Mar;11(3):150-1. Unique Identifier : AIDSLINE MED/94281484
Povar Marco J; Alvarez Alegret R; Arazo Garces P; Ramos Paesa C; Aguirre Errasti JM
Late renal allograft failure secondary to thrombotic microangiopathy-human immunodeficiency virus nephropathy.
J Am Soc Nephrol. 1994 Mar;4(9):1643-8. Unique Identifier : AIDSLINE MED/94281578
Frem GJ; Rennke HG; Sayegh MH; Department of Medicine, Brigham and Women's Hospital, Boston, MA; 02115.
The case of a renal transplant recipient with a known history of iv drug abuse but unknown human immunodeficiency virus (HIV) status who presents after having a stable renal allograft function for 4 yr, with acute/subacute advanced renal failure, nephrotic syndrome, and hypertension, as well as clinical and histologic


Disseminated herpes zoster with multifocal neurologic involvement in an HTLV-1 carrier.
Intern Med. 1993 Nov;32(11):854-6. Unique Identifier : AIDSLINE MED/94281720
Fujii N; Itoh Y; Tomoda H; Department of Neurology, Iizuka Hospital, Fukuoka.
A 56-year-old previously healthy man suffered from an attack of disseminated herpes zoster, followed by multifocal neurologic involvement. The patient was a human T-cell lymphotropic virus type 1 (HTLV-1) carrier. HTLV-1 infection, even though normally asymptomatic, has been suggested to be one of the risk factors for


AIDS and dementia: 10 years on [editorial]
Br J Hosp Med. 1994 Feb 16-Mar 1;51(4):144, 147. Unique Identifier : AIDSLINE MED/94282417
Riccio M; Burgess A
Molecular biology of human herpesviruses 6A and 6B.
Infect Agents Dis. 1993 Dec;2(6):343-60. Unique Identifier : AIDSLINE MED/94282499
Inoue N; Dambaugh TR; Pellett PE; Centers for Disease Control and Prevention, Atlanta, Georgia; 30333.
Human herpesvirus 6 variant A (HHV-6A) and human herpesvirus 6 variant B (HHV-6B) are closely related herpesviruses. No disease has been specifically associated with HHV-6A, whereas HHV-6B is the major etiologic agent of exanthem subitum. Both viruses may be opportunistic pathogens in the immunocompromised patient. HH


Molecular properties of feline immunodeficiency virus (FIV).
Infect Agents Dis. 1993 Dec;2(6):361-74. Unique Identifier : AIDSLINE MED/94282500
Elder JH; Phillips TR; Department of Molecular Biology, Scripps Research Institute, La; Jolla, California 92037.
Marriage patterns among HTLV-I seropositive women in Japan [letter]
Cancer Lett. 1994 Jun 30;81(2):237-40. Unique Identifier : AIDSLINE MED/94282727
Umemoto M; Take H; Kusuhara K; Kuraya K
A significantly higher percentage of asymptomatic HTLV-I seropositive pregnant women in the Kagoshima prefecture were married to men who were also born in that prefecture compared with seronegative women [138/166(83.1%), 221/306 (72.2%); P


Mutations in the coding region of c-MYC in AIDS-associated and other aggressive lymphomas.
Cancer Res. 1994 Jul 1;54(13):3383-6. Unique Identifier : AIDSLINE MED/94282742
Clark HM; Yano T; Otsuki T; Jaffe ES; Shibata D; Raffeld M; Hematopathology Section, National Cancer Institute, NIH,; Bethesda, MD 20892.
Our previous studies of the translocated MYC gene in Burkitt s lymphoma showed the existence of clustered somatic mutations located in the transcriptional activation domain. We now report that aggressive lymphomas arising in the acquired immunodeficiency syndrome (AIDS) contain similar mutations and that the presence


Synthesis of galactosyl phosphate diester derivatives of nucleosides.
Carbohydr Res. 1994 May 5;257(2):323-30. Unique Identifier : AIDSLINE MED/94282804
Ma TW; Min JM; Zhang LH; School of Pharmaceutical Sciences, Beijing Medical University,; China.
ELISA-type titertray assay of IgM anti-GM1 autoantibodies.
Clin Chem. 1994 Jul;40(7 Pt 1):1331-4. Unique Identifier : AIDSLINE MED/94282916
Bech E; Jakobsen J; Orntoft TF; Department of Clinical Chemistry, Aarhus University Hospital,; Denmark.
We report an ELISA-type titertray assay for autoantibodies against the ganglioside GM1. Trays were coated with ganglioside GM1 and reacted with patients sera; bound IgM was detected with rabbit antibody to human IgM. High-titer serum from a patient was used as calibrator, another patient s serum as the positive contr


Prevalence of lymphopenia in children with AIDS.
Clin Pediatr (Phila). 1994 Apr;33(4):204-8. Unique Identifier : AIDSLINE MED/94282987
Suarez AD; Rao SP; Miller ST; Division of Hematology and Oncology, Children's Medical Center,; Brooklyn, New York.
Hematologic abnormalities, such as anemia, neutropenia, lymphopenia, and thrombocytopenia, are frequently observed in patients with acquired immunodeficiency syndrome (AIDS). While lymphopenia has been noted in up to 80% of adults, only 50% of children with AIDS are reported to be lymphopenic. We reviewed the blood co


Expanding the pediatrician's role in HIV prevention for adolescents.
Clin Pediatr (Phila). 1994 Apr;33(4):235-40. Unique Identifier : AIDSLINE MED/94282993
DiClemente RJ; Brown LK; School of Public Health, Department of Health Behavior,; University of Alabama, Birmingham 35294-2025.
The growing impact of the HIV/AIDS pandemic on children born to HIV-infected women.
Clin Perinatol. 1994 Mar;21(1):1-14. Unique Identifier : AIDSLINE MED/94283001
Chin J; School of Public Health, Department of BioMedical and; Environmental Sciences, University of California, Berkeley.
The increasing numbers of children born to HIV-infected women poses formidable problems for maternal and child health programs throughout the world. Between 20% and 40% of these children will be infected with HIV and most are expected to die by the age of 5 years as a result. The vast majority of the uninfected childr


Imaging of HIV infection in the prenatal and postnatal period.
Clin Perinatol. 1994 Mar;21(1):125-47. Unique Identifier : AIDSLINE MED/94283003
Marquis JR; Bardeguez AD; Department of Radiology, Children's Hospital of New Jersey,; Newark.
Prenatal diagnosis of maternal diseases common to HIV infection may alert the clinician to potential HIV infection in the infant, with resultant early diagnosis and treatment. Although of limited value in the first months of life, imaging studies can be beneficial in selected cases and may be the first clue to the dia


Congenital syphilis.
Clin Perinatol. 1994 Mar;21(1):149-62. Unique Identifier : AIDSLINE MED/94283004
Evans HE; Frenkel LD; Department of Pediatrics, University of Medicine and Dentistry of; New Jersey-New Jersey Medical School, Newark.
Congenital syphilis offers many parallels with perinatal HIV infection. Both affect multiple organs including the central nervous system, may be asymptomatic for months to years, and pose diagnostic dilemmas, especially from a laboratory perspective. Syphilis is a co-infection in some cases of HIV. Public policy issue


Ethical issues in perinatal HIV.
Clin Perinatol. 1994 Mar;21(1):15-28. Unique Identifier : AIDSLINE MED/94283005
Bonkovsky FO; National Institutes of Health, Bethesda, Maryland.
Perinatal HIV raises difficult ethical issues and value conflicts for practitioners, patients, and the public. Part I gives an overview of US infant HIV realities and the devastating worldwide HIV and tuberculosis pandemics. In part II, the major ethical issues regarding perinatal HIV including confidentiality, advanc


Quo vadis: perinatal AIDS issues--2004.
Clin Perinatol. 1994 Mar;21(1):179-98. Unique Identifier : AIDSLINE MED/94283007
Weiss SH; Louria DB; Department of Preventive Medicine and Community Health,; University of Medicine and Dentistry of New Jersey-New Jersey; Medical School, Newark.
The HIV problem will inexorably increase over the next decade, with an increasing proportionate impact upon women and children over the next decade. HIV will become endemic, essentially worldwide. Some regions in the developed world may be relatively spared if current trends continue. This may reduce the willingness t


Public policy and AIDS.
Clin Perinatol. 1994 Mar;21(1):29-38. Unique Identifier : AIDSLINE MED/94283008
Evans HE; Department of Pediatrics, New Jersey Medical School, University; of Medicine and Dentistry of New Jersey, Newark.
In summary of some of the major issues raised by AIDS (Table 1), social, political, and economic forces all impact on the global outbreak of AIDS. Conversely the epidemiologic and medical realities of this disease have forced a reconsideration of moral and ethical values, prioritization of resource allocation, and per


The molecular biology of HIV. Insights into pathogenesis and targets for therapy.
Clin Perinatol. 1994 Mar;21(1):39-73. Unique Identifier : AIDSLINE MED/94283009
Zeichner SL; Pediatric Branch, National Cancer Institute, National Institutes; of Health, Bethesda, Maryland.
In the past 10 years, a large number of investigators have produced an enormous amount of information concerning the molecular biology of HIV. These studies at the most basic biological level have provided essential insights into the pathogenesis of the disease. They have supplied the information necessary for the cre


HIV in adolescents.
Clin Perinatol. 1994 Mar;21(1):75-84. Unique Identifier : AIDSLINE MED/94283010
Kaplan ME; Schonberg SK; Division of Adolescent Medicine, Albert Einstein College of; Medicine/Montefiore Medical Center, Bronx, New York.
Although the number of adolescents with diagnosed AIDS in the United States remains less than 1000, many more have HIV infection that has not yet manifested as clinical illness. In addition, most adolescents are involved in risk behaviors that potentially expose them to the virus. Medi


Perinatal HIV infection and AIDS.
Clin Perinatol. 1994 Mar;21(1):95-107. Unique Identifier : AIDSLINE MED/94283012
Frenkel LD; Gaur S; Department of Pediatrics, University of Medicine and Dentistry of; New Jersey, Robert Wood Johnson Medical School, New Brunswick.
This article provides a comprehensive review of the current understanding of the epidemiologic trends, diagnosis, and management of pediatric HIV infection and AIDS. Special emphasis is placed on the multisystem manifestations of pediatric HIV disease, and a rational systematic approach to management is discussed.


Social networks and daily activities of street youth in Belo Horizonte, Brazil. Street Youth Study Group.
Child Dev. 1994 Apr;65(2 Spec No):319-30. Unique Identifier : AIDSLINE MED/94283062
Campos R; Raffaelli M; Ude W; Greco M; Ruff A; Rolf J; Antunes CM; Halsey N; Greco D; Universidade Federal de Minas Gerais, Belo Horizonte.
Social networks and daily activities of children and adolescents living and/or working on the streets of a large Brazilian city were examined. Drawing on data collected through structured surveys, in-depth interviews, focus group discussions, and field observations, we described street youths family situation, social


Evolution of a disrupted TAR RNA hairpin structure in the HIV-1 virus.
EMBO J. 1994 Jun 1;13(11):2650-9. Unique Identifier : AIDSLINE MED/94283390
Klaver B; Berkhout B; University of Amsterdam, Department of Virology, Academic Medical; Center, The Netherlands.
Human immunodeficiency virus type 1 (HIV-1) RNA contains an extended hairpin structure at the 5 end (the TAR element) that is essential for viral replication. The upper part of the stem-loop structure binds the virally encoded transcriptional activator protein Tat and cellular co-factors, but no clear function for th


Thrombotic primary pulmonary hypertension in an HIV+ patient.
Eur Heart J. 1994 Mar;15(3):394-6. Unique Identifier : AIDSLINE MED/94283443
Heron E; Laaban JP; Capron F; Quieffin J; Brechot JM; Rochemaure J; Department of Pneumonology, Hotel-Dieu Hospital, Paris, France.
We report a case of severe primary pulmonary hypertension occurring in an HIV+ patient in whom lung biopsy and post-mortem examination were consistent with thrombotic pulmonary arteriopathy. To the best of our knowledge, this histological pattern has not been previously reported in HIV+ patients with primary pulmonary


Effect of sputum induction on arterial oxygen saturation and spirometry in HIV-infected patients.
Eur Respir J. 1994 Mar;7(3):453-8. Unique Identifier : AIDSLINE MED/94283558
Leigh TR; Kirby K; Gazzard BG; Collins JV; Dept of Respiratory Medicine, Chelsea and Westminster Hospital,; London, UK.
We wanted to study the effect of sputum induction on forced expiratory volume in one second (FEV1) and on oxygen saturation in normal controls, asymptomatic human immunodeficiency virus (HIV)-seropositive individuals, and HIV-seropositive patients under investigation for suspected Pneumocystis carinii pneumonia (PCP).


Inhibition of activity of the protease from bovine leukemia virus.
FEBS Lett. 1994 Jun 13;346(2-3):268-72. Unique Identifier : AIDSLINE MED/94283610
Menard A; Leonard R; Llido S; Geoffre S; Picard P; Berteau F; Precigoux G; Hospital M; Guillemain B; INSERM Unite 328, fondation Bergonie, Bordeaux, France.
In view of the close similarity between bovine leukemia virus (BLV) and human T-cell leukemia virus type I (HTLV-I) we investigated the possibility of developing specific inhibitors of the proteases of these retroviruses using the purified enzyme from BLV. We tested the ability of this protease to specifically cleave


Corneal endothelial changes in cytomegalovirus retinitis.
Eye. 1994;8 ( Pt 1):41-3. Unique Identifier : AIDSLINE MED/94283687
Mitchell SM; Barton K; Lightman S; Department of Clinical Science, Moorfields Eye Hospital, London,; UK.
Reticular deposits on the corneal endothelium together with fundus changes typical of cytomegalovirus ( CMV ) retinitis have been noted in patients with acquired immune deficiency syndrome (AIDS). The aim of this study was to c


[AIDS and abscess of the right iliac fossa (letter)]
Gastroenterol Clin Biol. 1994;18(2):179-80. Unique Identifier : AIDSLINE MED/94283786
Lironi A; Savioz D; Balavoine JF; Rohner A
Laparoscopic and histologic findings in patients with the human immunodeficiency virus.
Gastrointest Endosc. 1994 Mar-Apr;40(2 Pt 1):160-4. Unique Identifier : AIDSLINE MED/94283794
Jeffers LJ; Alzate I; Aguilar H; Reddy KR; Idrovo V; Cheinquer H; Hasan FA; Parker T; Montero C; Dickinson G; et al; Division of Hepatology, University of Miami School of Medicine,; Florida.
Hepatic dysfunction frequently develops in patients infected with the human immunodeficiency virus (HIV). This retrospective study was undertaken to determine the laparoscopic and histologic findings in a group of HIV-seropositive patients with or without the acquired immune deficiency syndrome (AIDS). Fifty-four pati


International workshop. Microsporidiosis and cryptosporidiosis in immunodeficient patients. September 28-October 1, 1993, Ceske Budejovice, Czech Republic. Proceedings.
Folia Parasitol (Praha). 1993;40(4):249-320. Unique Identifier : AIDSLINE MED/94283915
Introductory remarks on microsporidia in the AIDS era.
Folia Parasitol (Praha). 1993;40(4):255-6. Unique Identifier : AIDSLINE MED/94283916
Lom J; Institute of Parasitology, Academy of Sciences of the Czech; Republic, Ceske Budejovice.
An extremely rapid method for detection of microsporidia in biopsy materials from AIDS patients.
Folia Parasitol (Praha). 1993;40(4):273-4. Unique Identifier : AIDSLINE MED/94283920
Vavra J; Nohynkova E; Machala L; Spala J; Department of Parasitology, Charles University, Prague, Czech; Republic.
The phospholipids in Enterocytozoon bieneusi: an electron spectroscopic imaging study.
Folia Parasitol (Praha). 1993;40(4):275-8. Unique Identifier : AIDSLINE MED/94283921
Desportes-Livage I; Harper F; Hilmarsdottir I; Benhamou Y; Ombrouck C; Gentilini M; INSERM U 313, CHU Pitie-Salpetriere, Paris, France.
The treatment with ferriosmium of meronts and sporonts of the microsporidian Enterocytozoon bieneusi has shown the lamellar organization of the membranes of the endoplasmic reticulum and of the nuclear envelope. The Electron Spectroscopy Imaging (ESI), (Ottensmeyer and Andrew 1980) of unstained ultrathin sections of m


A species of Encephalitozoon isolated from an AIDS patient: criteria for species differentiation.
Folia Parasitol (Praha). 1993;40(4):293-5. Unique Identifier : AIDSLINE MED/94283924
Hollister WS; Canning EU; Colbourn NI; Department of Biology, Imperial College of Science, Technology; and Medicine, London, U.K.
A microsporidium isolated in vitro from urine of an AIDS patient was identified as a species of Encephalitozoon. Investigation of the isolate by electron microscopy, amplification of DNA by RAPD PCR, protein analysis by SDS-PAGE and Western blotting and infectivity to athymic mice revealed that it differs from establi


Antigenic characterization of human isolates of cryptosporidia.
Folia Parasitol (Praha). 1993;40(4):301-5. Unique Identifier : AIDSLINE MED/94283926
Ditrich O; Kopacek P; Kucerova Z; Institute of Parasitology, Academy of Sciences of the Czech; Republic, Ceske Budejovice.
Isolates of cryptosporidia from immunodeficient patients and from immunocompetent children suffering from diarrhoea were sources for preparation of antigens. Altogether, antigens from 21 isolates were obtained, 19 from children and 2 from AIDS patients. With one exception, all children were under 4 years old and most


Epstein-Barr-encoded RNA in situ hybridization: diagnostic applications.
Hum Pathol. 1994 Jun;25(6):602-5. Unique Identifier : AIDSLINE MED/94283949
Ambinder RF; Mann RB; Department of Oncology, Johns Hopkins School of Medicine,; Baltimore, MD.
Latent Epstein-Barr virus (EBV) infection is associated with a variety of malignancies and other diseases. Highly restricted viral antigen expression and low viral genome copy number in infected tissues impede conventional immunohistochemical or in situ hybridization approaches to the detection of virus in these tissu


Adjuvant effect of liposomes and adamantylamide dipeptide on antigenicity of entrapped synthetic peptide derived from HIV-1 transmembrane region glycoprotein gp41.
Immunol Lett. 1994 Feb;39(2):157-61. Unique Identifier : AIDSLINE MED/94283963
Turanek J; Toman M; Novak J; Krchnak V; Horavova P; Veterinary Research Institute, Brno, Czech Republic.
The synthetic peptide antigen (Ag) (the primary structure Tyr-Leu-Lys-Asp-Gln-Gln-Leu-Leu-Gly-Ile-Trp-Gly-Cys-Ser-Gly-Lys-L- eu-Ile- Cys-Thr derived from the envelope glycoprotein gp41 of the human immunodeficiency virus type 1 (HIV-1) and exerting specificity with all HIV-1-positive sera available in the


The differential pattern of memory deficit in normal aging and dementias of different etiology.
J Clin Psychol. 1994 Mar;50(2):246-52. Unique Identifier : AIDSLINE MED/94284357
Mitrushina M; Satz P; Drebing C; Van Gorp W; Mathews A; Harker J; Chervinsky A; UCLA School of Medicine, California State University, Northridge; Olive View/UCLA Medical Center.
The study explored encoding, storage, and retrieval components of memory functioning in four groups of subjects: (1) normal elderly; (2) elderly subjects in the early prestages of DAT; (3) elderly subjects with a more advanced DAT; (4) younger subjects in the early prestages of AIDS de


Measuring dentists' willingness to treat HIV-positive patients.
J Am Dent Assoc. 1994 Jun;125(6):705-10. Unique Identifier : AIDSLINE MED/94284454
Sadowsky D; Kunzel C; Division of Community Health, Columbia University School of; Dental and Oral Surgery, New York 10032.
This survey of urban dentists found that willingness to treat HIV-positive patients was not a dichotomous decision. Variables that influence a dentist s willingness to treat these patients are identified. Other studies and the impact of willingness to care are considered.


Multiple herpesviruses in saliva of HIV-infected individuals.
J Am Dent Assoc. 1994 Jun;125(6):713-9. Unique Identifier : AIDSLINE MED/94284455
Fons MP; Flaitz CM; Moore B; Prabhakar BS; Nichols CM; Albrecht T; Department of Microbiology, University of Texas Medical Branch at; Galveston.
Oral infections with human herpesviruses cause increased morbidity in patients infected with HIV. In this study, multiple HHVs were often isolated from the saliva of HIV-seropositive dental patients, but their isolation rate did not differ substantially from rates reported for the general population, except for human


Controlling resurgent tuberculosis: public health agencies, public policy, and law.
J Health Polit Policy Law. 1994 Spring;19(1):107-47. Unique Identifier : AIDSLINE MED/94284534
Gittler J; University of Iowa.
The reappearance of tuberculosis as a serious public health threat points up the fallacy of the widely held assumption that medical science had conquered the communicable diseases that were once leading causes of morbidity and mortality. In devising a strategy to prevent the spread of TB, public policymakers must adap


Public health policy and tuberculosis.
J Health Polit Policy Law. 1994 Spring;19(1):149-54. Unique Identifier : AIDSLINE MED/94284535
Bayer R; Columbia University.
The importance of public health for twenty-first-century health care: lessons from tuberculosis.
J Health Polit Policy Law. 1994 Spring;19(1):155-63. Unique Identifier : AIDSLINE MED/94284536
Bovbjerg RR; Urban Institute.
Once epidemic, tuberculosis has re-emerged, often in newly drug-resistant forms. This public health threat calls for strong public action as well as improved private care. Action has been hampered by failures in public health infrastructure and legal-philosophical support for government intervention. Josephine Gittler


The $147,000 misunderstanding: repercussions of overestimating the cost of AIDS.
J Health Polit Policy Law. 1994 Spring;19(1):69-90. Unique Identifier : AIDSLINE MED/94284552
Green J; Oppenheimer GM; Wintfeld N; New York University Medical Center.
The increasing incidence of AIDS in the 1980s prompted inquiry into the resources required to meet projected needs. In the first economic study to appear on the illness, the Centers for Disease Control (CDC) estimated that the costs of inpatient care were $147,000 per AIDS patient, heightening concern that the health


Multidrug-resistant tuberculosis in the New York State prison system, 1990-1991.
J Infect Dis. 1994 Jul;170(1):151-6. Unique Identifier : AIDSLINE MED/94284630
Valway SE; Greifinger RB; Papania M; Kilburn JO; Woodley C; DiFerdinando GT; Dooley SW; Division of Tuberculosis Elimination, Centers for Disease Control; and Prevention, Atlanta, GA 30333.
Three epidemiologically linked multidrug-resistant (MDR) tuberculosis (TB) outbreaks in 1990-1991 involving New York State (NYS) inmates suggested MDR-TB was widespread in NYS prisons. Inmate lists were linked to 1990-1992 TB registries, medical records were reviewed, and movement histories for inmates with MDR-TB wer


The individual microbiologic effect of three antimycobacterial agents, clofazimine, ethambutol, and rifampin, on Mycobacterium avium complex bacteremia in patients with AIDS.
J Infect Dis. 1994 Jul;170(1):157-64. Unique Identifier : AIDSLINE MED/94284631
Kemper CA; Havlir D; Haghighat D; Dube M; Bartok AE; Sison JP; Yao Y; Yangco B; Leedom JM; Tilles JG; et al; Division of Infectious Diseases, Santa Clara Valley Medical; Center, San Jose, CA 95128.
The individual antibacterial activities of clofazimine, ethambutol, and rifampin in the treatment of Mycobacterium avium complex bacteremia in patients with AIDS were determined. Sixty human immunodeficiency virus 1-infected patients who had at least one blood culture positive for M. avium complex were randomized to r


Trimetrexate with leucovorin versus trimethoprim-sulfamethoxazole for moderate to severe episodes of Pneumocystis carinii pneumonia in patients with AIDS: a prospective, controlled multicenter investigation of the AIDS Clinical Trials Group Protocol 029/031.
J Infect Dis. 1994 Jul;170(1):165-72. Unique Identifier : AIDSLINE MED/94284632
Sattler FR; Frame P; Davis R; Nichols L; Shelton B; Akil B; Baughman R; Hughlett C; Weiss W; Boylen CT; et al; Department of Medicine, Los Angeles County-University of Southern; California Medical Center 90033.
Trimetrexate is a powerful inhibitor of the dihydrofolate reductase of Pneumocystis carinii. AIDS patients (n = 215) with moderate to severe P. carinii pneumonia were enrolled in a double-blind study of trimetrexate plus leucovorin versus trimethoprim-sulfamethoxazole (TMP-SMZ) for 21 days. By study day 10, study ther


Randomized phase I trial of two different combination foscarnet and ganciclovir chronic maintenance therapy regimens for AIDS patients with cytomegalovirus retinitis: AIDS clinical Trials Group Protocol 151.
J Infect Dis. 1994 Jul;170(1):189-93. Unique Identifier : AIDSLINE MED/94284635
Jacobson MA; Kramer F; Bassiakos Y; Hooton T; Polsky B; Geheb H; O'Donnell JJ; Walker JD; Korvick JA; van der Horst C
AIDS patients with newly diagnosed cytomegalovirus ( CMV ) retinitis who had just completed a 14-day course of ganciclovir induction therapy were randomly assigned to an alternating or concurrent combination regimen of chronic


Unsuspected primary human immunodeficiency virus type 1 infection in seronegative emergency department patients.
J Infect Dis. 1994 Jul;170(1):194-7. Unique Identifier : AIDSLINE MED/94284636
Clark SJ; Kelen GD; Henrard DR; Daar ES; Craig S; Shaw GM; Quinn TC; Department of Medicine, University of Alabama at Birmingham.
To estimate the number of recently infected patients in the window period before human immunodeficiency virus type 1 (HIV-1) seroconversion among patients seeking medical care, randomly selected adults presenting to an inner city emergency department were tested for HIV-1 antibody and p24 antigen. Of 2300 patients enr


Temporal trends of opportunistic infections and malignancies in homosexual men with AIDS.
J Infect Dis. 1994 Jul;170(1):198-202. Unique Identifier : AIDSLINE MED/94284637
Katz MH; Hessol NA; Buchbinder SP; Hirozawa A; O'Malley P; Holmberg SD; Department of Public Health, San Francisco, California; 94102-6033.
Temporal changes in the lifetime occurrence of opportunistic infections and malignancies among 1115 homosexual men diagnosed with AIDS were examined. Information from the AIDS surveillance registry, hospital pathology and microbiology logs, patient chart reviews, cancer registries, and death certificates was used to c


Rapid decrease in unintegrated human immunodeficiency virus DNA after the initiation of nucleoside therapy.
J Infect Dis. 1994 Jul;170(1):202-5. Unique Identifier : AIDSLINE MED/94284639
Donovan RM; Bush CE; Smereck SM; Baxa DM; Markowitz NP; Saravolatz LD; Department of Internal Medicine, Henry Ford Hospital, Detroit,; Michigan 48202.
Better markers for determining therapeutic efficacy of antiretroviral drugs are needed for human immunodeficiency virus (HIV) infection. The amounts of unintegrated HIV DNA (uDNA) were sequentially determined in peripheral blood mononuclear cells (PBMC) from 20 HIV-infected patients starting nucleoside therapy. HIV co


Transmission of human T cell lymphotropic virus (HTLV) type II by transfusion of HTLV-I-screened blood products.
J Infect Dis. 1994 Jul;170(1):206-10. Unique Identifier : AIDSLINE MED/94284640
Rios M; Khabbaz RF; Kaplan JE; Hall WW; Kessler D; Bianco C; New York Blood Center, NY 10021.
Blood donors have been screened for antibodies to human T cell lymphotropic virus (HTLV) type I since December 1988. Screening for HTLV-II has been simultaneously done because of cross-reactivity between antibodies to the two viruses. Currently,


Human herpesvirus 6: a survey of presence and variant distribution in normal peripheral lymphocytes and lymphoproliferative disorders.
J Infect Dis. 1994 Jul;170(1):211-5. Unique Identifier : AIDSLINE MED/94284641
Di Luca D; Dolcetti R; Mirandola P; De Re V; Secchiero P; Carbone A; Boiocchi M; Cassai E; Institute of Microbiology, University of Ferrara, Italy.
The presence and distribution of human herpesvirus 6 (HHV-6) variants was investigated by polymerase chain reaction in samples from healthy donors and biopsies from non-Hodgkin s lymphomas and Hodgkin s disease. HHV-6 DNA was present in peripheral blood lymphocytes of 17% of healthy donors, variant B three times more


High-dose fluconazole for treatment of cryptococcal disease in patients with human immunodeficiency virus infection. The California Collaborative Treatment Group.
J Infect Dis. 1994 Jul;170(1):238-42. Unique Identifier : AIDSLINE MED/94284648
Haubrich RH; Haghighat D; Bozzette SA; Tilles J; McCutchan JA; Department of Medicine, University of California, San Diego; 92103.
Eight patients (6, cryptococcal meningitis; 2, high-titer cryptococcal antigenemia) were treated with 800 mg/day fluconazole to assess the safety and efficacy of high-dose fluconazole as primary therapy. Five patients with meningitis had resolution of clinical symptoms and all 6 had negative cerebrospinal fluid (CSF)


Look-back investigation follow-up [letter; comment]
J Infect Dis. 1994 Jul;170(1):254. Unique Identifier : AIDSLINE MED/94284653
Danila RN; MacDonald KL; Osterholm MT
Clustering of human T lymphotropic virus type I seropositive in Montserrat, West Indies: evidence for an environmental factor in transmission of the virus.
J Infect Dis. 1994 Jul;170(1):44-50. Unique Identifier : AIDSLINE MED/94284660
Miller GJ; Lewis LL; Colman SM; Cooper JA; Lloyd G; Scollen N; Jones N; Tedder RS; Greaves MF; Medical Research Council Epidemiology and Medical Care Unit,; Medical College of St. Bartholomew's Hospital, London.
A community survey of human T cell lymphotropic virus type I (HTLV-I) in Montserrat , West Indies, identified 22 instances in which 2 HTLV-I-seropositive adults lived within 60 m of each other (close pairs), compared with 7.8 expecte


Prolonged clinical latency and survival of macaques given a whole inactivated simian immunodeficiency virus vaccine.
J Infect Dis. 1994 Jul;170(1):51-9. Unique Identifier : AIDSLINE MED/94284661
Hirsch VM; Goldstein S; Hynes NA; Elkins WR; London WT; Zack PM; Montefiori D; Johnson PR; Immunodeficiency Viruses Section, National Institute of Allergy; and Infectious Diseases, National Institutes of Health, Bethesda,; Maryland.
Simian immunodeficiency virus (SIV) infection of macaques is a useful and relevant model for evaluating candidate human immunodeficiency virus (HIV) vaccines. One important feature of this model is that SIV vaccines can be evaluated for their ability to prevent infection as well as to prevent or delay the onset of AID


Human immunodeficiency virus (HIV)-infected human blood monocytes and peritoneal macrophages have reduced anticryptococcal activity whereas HIV-infected alveolar macrophages retain normal activity.
J Infect Dis. 1994 Jul;170(1):60-7. Unique Identifier : AIDSLINE MED/94284662
Cameron ML; Granger DL; Matthews TJ; Weinberg JB; Division of Infectious Diseases, Duke University Medical Center,; Durham, NC 27710.
Human immunodeficiency virus type 1 (HIV-1) infection causes immune dysfunction. Mononuclear phagocytes (MNP) are immune effector cells against some intracellular pathogens and reservoirs for HIV-1. This study determined effects of HIV-1 on MNP-mediated antifungal function. MNP from seronegative volunteers were inocul


Phenotypic and genotypic characterization of acyclovir-resistant varicella-zoster viruses isolated from persons with AIDS.
J Infect Dis. 1994 Jul;170(1):68-75. Unique Identifier : AIDSLINE MED/94284663
Boivin G; Edelman CK; Pedneault L; Talarico CL; Biron KK; Balfour HH Jr; Dept. of Laboratory Medicine and Pathology, Minneapolis, MN; 55455-0392.
Phenotypic and genotypic analyses were done on 17 varicella-zoster virus (VZV) isolates recovered from 10 persons with AIDS (mean CD4 cell count, 16.4/mm3) who had chronic VZV lesions. Eleven acyclovir-resistant isolates were recovered from 10 patients after a mean of 20.1 weeks of therapy. Six susceptible isolates we


Electrolyte and acid-base disorders associated with AIDS: an etiologic review.
J Gen Intern Med. 1994 Apr;9(4):232-6. Unique Identifier : AIDSLINE MED/94284920
Perazella MA; Brown E; Yale Primary Care Residency Program, Department of Medicine, St.; Mary's Hospital, Waterbury, Connecticut 06706.
In summary, patients with HIV infection may develop a bewildering variety of electrolyte and acid-base disturbances. Hyponatremia from many causes is common and associated with an increased mortality. Potassium disorders are frequent, with hyperkalemia, even to life-threatening levels, more common than hypokalemia. Di


Acute arthritis and human immunodeficiency virus infection in Rwanda.
J Rheumatol. 1993 Dec;20(12):2123-7. Unique Identifier : AIDSLINE MED/94285162
Blanche P; Taelman H; Saraux A; Bogaerts J; Clerinx J; Batungwanayo J; Kagame A; Sicard D; Menkes CJ; Van de Perre P; Department of Internal Medicine, Centre Hospitalier de Kigali,; Rwanda.
OBJECTIVE. To determine the etiology of acute arthritis observed in adults and to define its relationship with human immunodeficiency virus 1 (HIV-1) infection in Kigali, capital city of Rwanda . METHODS. From September 1, 1989 until March 31, 1990 we conducted a study of all new pa


HTLV-I and Behcet's disease [letter]
J Rheumatol. 1993 Dec;20(12):2175-6. Unique Identifier : AIDSLINE MED/94285181
Igakura T; Kawahigashi Y; Kanazawa H; Nakagawa M; Osame M
Pediatric morbidity in a hospital of Kampala, Uganda from 1985 to 1990 [letter]
J Trop Pediatr. 1994 Apr;40(2):119-20. Unique Identifier : AIDSLINE MED/94285252
Muller O; Sen G; Moser R
Breastfeeding during the HIV epidemic. The dilemma: preventing vertical transmission or preventing death [editorial]
J Trop Pediatr. 1994 Apr;40(2):64-5. Unique Identifier : AIDSLINE MED/94285257
Cutting WA
[AIDS telephone counseling on night time, weekends and holidays by Niigata Prefectural Nursing Association]
Kango. 1993 Dec;45(15):73-81. Unique Identifier : AIDSLINE MED/94285442
Saitoh K
Characterization of caprine microglial cells and in vitro infection with caprine arthritis-encephalitis lentivirus.
Lab Invest. 1994 Jun;70(6):933-43. Unique Identifier : AIDSLINE MED/94285537
Baszler TV; Harwood WG; Lester KL; Davis WC; Knowles DP; Department of Veterinary Microbiology and Pathology, College of; Veterinary Medicine, Washington State University, Pullman.
BACKGROUND: Similar to human immunodeficiency virus-1 and simian immunodeficiency virus-1, microglial cells in brain tissue are a major cell target for infection with caprine arthritis-encephalitis lentivirus (CAEV) in vivo. These observations have raised interest in the role of microglial cells in the development of


Rat Rev-erbA alpha, an orphan receptor related to thyroid hormone receptor, binds to specific thyroid hormone response elements.
Mol Endocrinol. 1994 Mar;8(3):286-95. Unique Identifier : AIDSLINE MED/94285930
Spanjaard RA; Nguyen VP; Chin WW; Department of Medicine, Brigham and Women's Hospital, Boston, MA; 02115.
Rat Rev-erbA alpha (rRev), which is related to thyroid hormone receptor (TR), is a conserved member of the nuclear hormone receptor superfamily whose physiological roles are unknown (orphan receptor). We studied DNA binding of rRev in vitro by electrophoretic mobility shift assay. A fusion protein was constructed, cal


Multiple prolactin-responsive elements mediate G1 and S phase expression of the interferon regulatory factor-1 gene.
Mol Endocrinol. 1994 Mar;8(3):345-55. Unique Identifier : AIDSLINE GENBANK/X72020
Stevens AM; Yu-Lee LY; Department of Microbiology and Immunology, Baylor College of; Medicine, Houston, Texas 77030.
The interferon regulatory factor-1 (IRF-1) gene is both an immediate-early G1 phase gene and an S phase gene inducible by PRL in rat Nb2 T lymphocytes. To understand the mechanism by which PRL regulates the biphasic expression of IRF-1, we cloned the rat IRF-1 gene and functionally characterized the IRF-1 promoter. Up


Comparative efficacy and safety of bifonazole 1% cream and the corresponding base preparation in the treatment of seborrhoeic dermatitis.
Mycoses. 1993 Sep-Oct;36(9-10):325-31. Unique Identifier : AIDSLINE MED/94285960
Zienicke H; Korting HC; Braun-Falco O; Effendy I; Hagedorn M; Kuchmeister B; Meisel C; Dermatologische Klinik und Poliklinik,; Ludwig-Maximilians-Universitat, Munich, Germany.
Seborrhoeic dermatitis is a common entity that conventionally is difficult to treat. Recently, topical ketoconazole has been proven successful. To determine if other azoles, and in particular the more modern ones, are also helpful in this condition, a double-blind multicentre randomized controlled trial was performed


No news on Sunday [editorial]
Nature. 1994 Jul 7;370(6484):1-2. Unique Identifier : AIDSLINE MED/94285990
[Surgical treatment of anorectal disorders in 32 HIV-seropositive patients]
Ned Tijdschr Geneeskd. 1994 Jun 11;138(24):1227-30. Unique Identifier : AIDSLINE MED/94286024
Sars PR; Slors JF; Taat CW; Academisch Medisch Centrum, afd. Chirurgie, Amsterdam.
OBJECTIVE. To describe the presentation and surgical treatment of anorectal pathology in HIV seropositive patients. DESIGN. Retrospective study. SETTING. Department of surgery, University Medical Centre, Amsterdam, the Netherlands . METHODS. Retrospective review of the records


[Immunoprophylaxis in the patient at risk. Problems, available vaccines, responses]
Minerva Med. 1993 Nov;84(11):583-8. Unique Identifier : AIDSLINE MED/94286093
Soranzo ML; Busso M
[A case of Reiter syndrome in HIV infection]
Minerva Med. 1993 Nov;84(11):633-6. Unique Identifier : AIDSLINE MED/94286100
Riccio A; Farinaro C; Maisto G; Natale D; Pronesti G; Secondo Policlinico-Cattedra di Metodologia Clinica, Universita; degli Studi di Napoli.
The onset of Acquired Immunodeficiency Syndrome (AIDS) is often characterized by a variety of symptoms, with the involvement of several tissues and organs. In the present case a polyarthritic syndrome was the symptomatology at the onset. Clinical onset. A 26 year old man, drug abuser, anti HIV positive, with a CD4/CD8


[Laser conization guided by endocervical staining with methylene blue]
Minerva Ginecol. 1994 Mar;46(3):69-73. Unique Identifier : AIDSLINE MED/94286109
Sopracordevole F; Campagnutta E; Parin A; Scarabelli C; Divisione di Oncologia Chirurgica Ginecologica, Centro di; Riferimento Oncologico, Aviano, PN.
The authors report their experience of the use of a vital stain--methylene blue--as a surgical guide in laser cervical conization for CIN2-CIN3/CIS. During the period 1 October 1991-31 December 1992 a total of 40 laser cervical conizations were performed under local anesthesia using a CO2 laser connected to a microhan


Tetrodotoxin blocks HIV coat protein (gp120) toxicity in primary neuronal cultures.
Neurosci Lett. 1994 Jan 3;165(1-2):187-90. Unique Identifier : AIDSLINE MED/94286141
Diop AG; Lesort M; Esclaire F; Sindou P; Couratier P; Hugon J; Unite de Neurobiologie Cellulaire, Faculte de Medecine,; Limoges, France.
HIV-1-associated cognitive/motor complex is a frequent neurological complication of the acquired immunodeficiency syndrome (AIDS). The pathogenesis of this syndrome implicates immunopathological and toxic events such as the production of cytokines. The HIV envelope glycoprotein gp120 seems also to play a major role in


Prophylactic application of an intra-alveolar socket medicament to reduce postextraction complications in HIV-seropositive patients.
Oral Surg Oral Med Oral Pathol. 1994 Apr;77(4):331-4. Unique Identifier : AIDSLINE MED/94286221
Pankhurst CL; Lewis DA; Clark DT; Kings College School of Medicine and Dentistry, London, England.
A prospective, controlled trial was performed to investigate the effect of a prophylactic socket medicament containing chlortetracycline, aspirin, and local anesthetics, in reducing the incidence of postextraction pain and infection in patients who are HIV-seropositive. Fifty patients were in the study; 25 received th


Oral manifestations associated with HIV-related disease as markers for immune suppression and AIDS.
Oral Surg Oral Med Oral Pathol. 1994 Apr;77(4):344-9. Unique Identifier : AIDSLINE MED/94286224
Glick M; Muzyka BC; Lurie D; Salkin LM; Temple University School of Dentistry, Philadelphia, Pa.
BACKGROUND. Oral lesions are common findings in HIV-related disease, but little is known about their significance in predicting immune suppression among a representative group of HIV-infected persons. METHODS. Oral examinations were performed on 454 patients who came to an outpatient dental clinic for dental care. CD4


[Future possibilities of drug therapy of acquired immunodeficiency syndrome]
Orv Hetil. 1994 Jun 5;135(23):1235-42. Unique Identifier : AIDSLINE MED/94286246
Balint GS; Szent-Gyorgyi Albert Orvostudomanyi Egyetem, Szeged.
Human Immunodeficiency Virus replication offers several targets for inhibitory compounds, the foremost presently being the HIV reverse transcriptase. Since the beginning of the epidemic three nucleoside analogue drugs--Zidovudine, Didanosine and Zalcitabine--which act at the reverse transcriptase enzyme are already li


Pathogenesis of vertical HIV-1 infection: implications for intervention and management.
Pediatr Ann. 1994 Mar;23(3):159-66. Unique Identifier : AIDSLINE MED/94286294
Luzuriaga K; Sullivan JL; Dept of Pediatrics, University of Massachusetts Medical School,; Worcester 01605.
HIV/AIDS and related issues forum.
N J Nurse. 1994 Jun;24(5):7. Unique Identifier : AIDSLINE MED/94286336
HIV bills in the legislature.
N J Nurse. 1994 Jun;24(5):7-8. Unique Identifier : AIDSLINE MED/94286337
Wachter MB
HIV/AIDS professional education grant update.
N J Nurse. 1994 Jun;24(5):7-8. Unique Identifier : AIDSLINE MED/94286338
Wurmser T
Health promotion. Total tension.
Nurs Times. 1994 Jun 8-14;90(23):29-30. Unique Identifier : AIDSLINE MED/94286359
Jervis M
The role of the school nurse in providing sex education.
Nurs Times. 1994 Jun 8-14;90(23):36-8. Unique Identifier : AIDSLINE MED/94286361
Cohen P
School and family planning nurses are well placed to promote high quality sex education to children and young people. Parents and teachers are often seen as authority figures whereas the nurse is an independent health professional. Government guidelines encourage liaison with teachers and this article--the second in a


Poor most at risk from AIDS [interview]
Nurs Times. 1994 Jun 8-14;90(23):7. Unique Identifier : AIDSLINE MED/94286367
Gillies P
Inhibition of human immunodeficiency virus type 1 integrase by 3'-azido-3'-deoxythymidylate.
Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):5771-5. Unique Identifier : AIDSLINE MED/94286520
Mazumder A; Cooney D; Agbaria R; Gupta M; Pommier Y; Laboratory of Molecular Pharmacology, National Cancer Institute,; Bethesda, MD 20892.
The effects of 3 -azido-3 -deoxythymidine ( AZT ) and three of its intracellular metabolites, azido- thymidine mono-, di-, and triphosphates, on the human immunodeficiency virus type 1 integrase have been determined. AZT mono-, di-, and triphosphate hav


Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core.
Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):5913-7. Unique Identifier : AIDSLINE MED/94286548
Pruss D; Bushman FD; Wolffe AP; Laboratory of Molecular Embryology, National Institute of Child; Health and Human Development, National Institutes of Health,; Bethesda, MD 20892.
We have examined the consequences of DNA distortion and specific histone-DNA contacts within the nucleosome for integration mediated by the human immunodeficiency virus (HIV)-encoded integrase enzyme. We find that sites of high-frequency integration cluster in the most severely deformed, kinked DNA regions within the


Combined intra- and extracellular immunization against human immunodeficiency virus type 1 infection with a human anti-gp120 antibody.
Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):5932-6. Unique Identifier : AIDSLINE MED/94286552
Chen SY; Khouri Y; Bagley J; Marasco WA; Department of Medicine, Dana-Farber Cancer Institute, Harvard; Medical School, Boston, MA 02115.
In this study, a human CD4+ T lymphocyte line was transduced to secrete Fab fragments of a broadly neutralizing human monoclonal antibody F105 that reacts with the CD4-binding site of human immunodeficiency virus type 1 (HIV-1) envelope protein. In the transduced cells infected with HIV-1, the nascent Fab fragments bi


RNase inhibition of human immunodeficiency virus infection of H9 cells.
Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6012-6. Unique Identifier : AIDSLINE MED/94286568
Youle RJ; Wu YN; Mikulski SM; Shogen K; Hamilton RS; Newton D; D'Alessio G; Gravell M; Biochemistry Section, Surgical Neurology Branch, National; Institute of Neurological Disorders and Stroke, National; Institutes of Health, Bethesda, MD 20892.
Onconase and bovine seminal RNase, two members of the RNase A superfamily, inhibit human immunodeficiency virus type 1 replication in H9 leukemia cells 90-99.9% over a 4-day incubation at concentrations not toxic to uninfected H9 cells. Two other members of the same protein family, bovine pancreatic RNase A and human


Glucosidase inhibition assay as prescreen for natural products.
P R Health Sci J. 1994 Mar;13(1):13-5. Unique Identifier : AIDSLINE MED/94286767
Antoun MD; Rios YR; Mendoza NT; Proctor G; Department of Pharmaceutical Sciences, School of Pharmacy,; University of Puerto Rico, San Juan 00936-5067.
A glucosidase inhibition assay has been used to evaluate extracts from higher plants. An enzyme inhibition of fifty percent or more correlated with the observed cytotoxicity of the extracts.


[Molecular basis for HIV infection: implication for the therapy]
Tanpakushitsu Kakusan Koso. 1994 Jun;39(8):1411-24. Unique Identifier : AIDSLINE MED/94286858
Nakaya T; Fujinaga K; Nishino Y; Kishi M; Ikuta K; Section of Serology, Hokkaido University, Sapporo, Japan.
[Viral genes of simian immunodeficiency viruses and their roles on the infectivity and pathogenicity]
Tanpakushitsu Kakusan Koso. 1994 Jun;39(8):1425-37. Unique Identifier : AIDSLINE MED/94286859
Ido E; Hayami M; Research Center for Immunodeficiency Virus, Kyoto University,; Japan.
[Inhibition of gene expression by antisense DNA]
Tanpakushitsu Kakusan Koso. 1994 Jun;39(8):1466-73. Unique Identifier : AIDSLINE MED/94286863
Takaku H; Hatta T; Tsukahara S; Department of Industrial Chemistry, Chiba Institute of; Technology, Japan.
[Tuberculosis]
Rev Med Suisse Romande. 1994 May;114(5):483-5. Unique Identifier : AIDSLINE MED/94287067
Bonard EC
A human T-cell lymphotropic virus type I carrier with temporal arteritis terminating in acute myelogenous leukemia.
Scand J Rheumatol. 1994;23(3):151-3. Unique Identifier : AIDSLINE MED/94287130
Shimamoto Y; Matsunaga C; Suga K; Fukushima N; Nomura K; Yamaguchi M; Department of Internal Medicine, Saga Medical School, Japan.
A human T-cell lymphotropic virus type I (HTLV-I) carrier with temporal arteritis (TA) in whom acute myelogenous leukemia (AML) developed 1 year after successful treatment of the autoimmune disease is described. This case suggested that the induction of immunodeficiency by infection with HTLV-I may be related to the d


NIH AIDS office clings to power [news]
Science. 1994 Jul 1;265(5168):19. Unique Identifier : AIDSLINE MED/94287195
AIDS research. U.S.-French patent dispute heads for a showdown [news]
Science. 1994 Jul 1;265(5168):23-5. Unique Identifier : AIDSLINE MED/94287198
Cohen J
Case report 836: Malignant large cell lymphoma of sacrum.
Skeletal Radiol. 1994 Apr;23(3):232-5. Unique Identifier : AIDSLINE MED/94287227
Ackerman L; Van Drunen M; Reyes CV; Nuclear Medicine Service, Edward Jr. Hines Veterans; Administration Hospital, Hines, Illinois.
We present a case of PLB found in the sacrum in an HIV-seropositive patient who had low back pain radiating to the lower extremities. To the best of our knowledge this is the first report of this kind. Multiple imaging techniques, including MRI, could not reliably differentiate between neoplasm and infection. Both pro


Tropical respiratory medicine. 2. Impact of human immunodeficiency virus on tuberculosis in developing countries.
Thorax. 1994 May;49(5):511-8. Unique Identifier : AIDSLINE MED/94287326
Nunn PP; Elliott AM; McAdam KP; Department of Clinical Sciences, London School of Hygiene and; Tropical Medicine.
Endobronchial HIV associated lymphoma.
Thorax. 1994 May;49(5):525-6. Unique Identifier : AIDSLINE MED/94287330
Keys TC; Judson MA; Reed CE; Sahn SA; Division of Pulmonary and Critical Care Medicine, Medical; University of South Carolina, Charleston 29425.
A 27 year old HIV infected man presented with two days of haemoptysis. Flexible bronchoscopy revealed a large carinal mass partially obstructing the left and right main stem bronchi. Rigid bronchoscopy was required to make the diagnosis of large cell immunoblastic lymphoma.


Tuberculosis and HIV: light after darkness [editorial]
Thorax. 1994 Jun;49(6):537-9. Unique Identifier : AIDSLINE MED/94287339
Grange JM; Stanford JL; Rook G; Onyebujoh P; Bretscher PA
Tropical respiratory medicine. 3. Histoplasmosis and pulmonary involvement in the tropics.
Thorax. 1994 Jun;49(6):598-601. Unique Identifier : AIDSLINE MED/94287353
Houston S; Division of Infectious Diseases, Walter Mackenzie Centre,; University of Alberta Hospitals, Edmonton, Canada.
[School children's knowledge of, need for and use of contraception before and after the AIDS campaigns. Knowledge and sources of information]
Ugeskr Laeger. 1994 Mar 7;156(10):1442, 1445-7. Unique Identifier : AIDSLINE MED/94287522
Rasmussen KL; Knudsen HJ
The purpose of the present paper was to investigate the influence of the AIDS-campaigns on adolescents knowledge of contraception and pregnancy and their sources of information. All pupils in their ninth school year in the municipality of Viborg answered an identical questionnaire in 1986 and 1993, dealing with the m


[School children's knowledge of, need for and use of contraception before and after the AIDS campaigns. Sexual activity and contraception habits]
Ugeskr Laeger. 1994 Mar 7;156(10):1447-8, 1451. Unique Identifier : AIDSLINE MED/94287523
Rasmussen KL; Knudsen HJ
The purpose of the present investigation was to evaluate changes in contraceptional habits or sexual activity among adolescents as a consequence of the AIDS-campaigns. In 1986 and 1993 all pupils in their ninth school year in the municipality of Viborg answered an identical questionnaire concerning the mentioned subje


[AIDS--prognosis and treatment (editorial)]
Ugeskr Laeger. 1994 Apr 25;156(17):2551. Unique Identifier : AIDSLINE MED/94287555
Nielsen JO; Skinhoj P
[Antiviral treatment of HIV infection]
Ugeskr Laeger. 1994 Apr 25;156(17):2555-6, 2559-60, 2563-5. Unique Identifier : AIDSLINE MED/94287557
Gerstoft J; Pedersen C; Mathiesen LR; Frederiksberg Hospital, medicinsk afdeling B.
During the past six years Zidovudine has been the main antiviral drug directed against HIV. The indications for its use have slowly been extended and a reduced dose has limited the side effects. The therapeutical gain is a survival benefit of three to nine months. Other nucleoside analogues such as didanosin and zalci


[HIV infection in children]
Ugeskr Laeger. 1994 Apr 25;156(17):2568-70, 2573-5. Unique Identifier : AIDSLINE MED/94287558
Christiansen CB; Heilmann CJ; Statens Seruminstitut, virologisk afdeling, Kobenhavn.
More children will be born infected with HIV in the years to come. Children with early symptoms will come into quick contact with a hospital, while others may be infected for up to ten years without presenting HIV-related symptoms. HIV infection can be diagnosed early with a combination of methods that are currently a


[HIV antibody positive children in Denmark]
Ugeskr Laeger. 1994 Apr 25;156(17):2575-9. Unique Identifier : AIDSLINE MED/94287559
Olofsson MJ; Scheibel E; Clausen N; Pedersen FK; Peitersen B; Dansk Paediatrisk Selskabs AIDS-udvalg, Kobenhavn.
The AIDS-committee of The Danish Society of Paediatrics has done a nation-wide study among infants and children under the age of 15 with AIDS or HIV-antibodies in preparation for planning prevention and treatment. Clinical data have been collected from the Departments of Paediatrics and Infectious Diseases, Haemophili


[Primers for the nef gene in the diagnosis of HIV infection using the polymerase chain reaction]
Vopr Virusol. 1994 Mar-Apr;39(2):53-6. Unique Identifier : AIDSLINE MED/94287653
Radiuk SN; Matsevich GR; Tarantul VZ; Andzhaparidze OG
A new system of primers and internal probe identifying the nef gene of HIV-1 was selected and tested for the laboratory diagnosis of HIV infection by means of PCR. The proposed primers and probe by their characteristics approached the optimal ones for PCR diagnosis. The diagnostic value of the above system was confirm


[Immunocytophotometric and cytogenetic analyses of T-lymphoblastoid cell lines in experimental HIV Infection]
Vopr Virusol. 1994 Mar-Apr;39(2):77-80. Unique Identifier : AIDSLINE MED/94287661
Kushch AA; Shumai EP; Glukhova LA; Magakin IuA; Avetisian AS; Kapantsian AM; Karalova EM; Grabovskaia IL
The accumulation of viral proteins p24 and gp41 in MT-4 cells was shown to occur asynchronously. No increase in the number of polydiploid cells, no polyploid mitoses or chromosome defects were found indicating the antiproliferative effect of HIV on MT-4 cells. A cyclic pattern of the infection course was observed in i


[Home care of AIDS patients from the medical and nursing viewpoint--a project in Vienna]
Acta Med Austriaca. 1994;21(1):14-6. Unique Identifier : AIDSLINE MED/94287772
Armbruster C; Vetter N; II. Internen Abteilung, Pulmologischen Zentrums der Stadt Wien.
Based on the longer survival time of HIV-infected patients the spectrum of HIV associated complications changed. The frequency of neurological diseases, as AIDS dementia complex, is increasing. Therefore there is more need for nursing of AIDS patients. Aim of the study was to evalu


Pretest counseling, informed consent and HIV testing [letter]
Am Fam Physician. 1994 Jul;50(1):48. Unique Identifier : AIDSLINE MED/94287869
Wagner RA
Variation of blood flow in the thoracic aorta during cardiac tamponade.
Am Heart J. 1994 Jul;128(1):190-3. Unique Identifier : AIDSLINE MED/94287892
Ho GM; Eisenberg MJ; Schiller NB; Department of Cardiovascular Medicine, Western Heart Institute,; San Francisco, CA 94117.
Pericardial effusion and pericardiocentesis in human immunodeficiency virus infection.
Am J Cardiol. 1994 Jul 1;74(1):94-6. Unique Identifier : AIDSLINE MED/94287937
Hsia J; Ross AM; Department of Medicine, George Washington University, Washington,; D.C 20037.
AIDS-associated cryptosporidiosis with gastric stricture and a therapeutic response to paromomycin.
Am J Gastroenterol. 1994 Jul;89(7):1096-8. Unique Identifier : AIDSLINE MED/94287995
Forester G; Sidhom O; Nahass R; Andavolu R; Department of Medicine, Robert Wood Johnson Medical School and; Medical Center at Princeton, New Jersey.
AIDS-associated cryptosporidiosis has been associated with severe, watery diarrhea and with multifocal biliary stricture. Gastric involvement has not been reported prominently. We report here the case of a 28-yr-old AIDS patient who developed typical watery diarrhea, followed by subtotal gastric obstruction secondary


Prevention of relapse of histoplasmosis with fluconazole in patients with the acquired immunodeficiency syndrome.
Am J Med. 1994 Jun;96(6):504-8. Unique Identifier : AIDSLINE MED/94288074
Norris S; Wheat J; McKinsey D; Lancaster D; Katz B; Black J; Driks M; Baker R; Israel K; Traeger D; et al; Department of Medicine, Indiana University School of Medicine,; Indianapolis.
OBJECTIVE: To assess the effectiveness of fluconazole for suppression of relapse of histoplasmosis in patients with acquired immunodeficiency syndrome (AIDS). DESIGN: Retrospective, nonrandomized, open trial. SETTING: Multicenter at two university referral centers and in five private practices. PATIENTS: Seventy-six p


Management of hospitalized intravenous drug users: role of the internist.
Am J Med. 1994 Jun;96(6):551-8. Unique Identifier : AIDSLINE MED/94288081
O'Connor PG; Samet JH; Stein MD; Department of Medicine, Yale University School of Medicine, New; Haven, Connecticut 06520-8025.
Intravenous drug users present significant clinical challenges to internists. In this paper, we review common clinical dilemmas faced by internists when managing intravenous drug users in the inpatient hospital setting. Articles were identified through a MEDLINE search and bibliographies of published articles. Studies


Public health interventions to reduce pediatric AIDS [editorial; comment]
Am J Public Health. 1994 Jul;84(7):1065-6. Unique Identifier : AIDSLINE MED/94288156
Goedert JJ; Cote TR
Voluntary and involuntary capture-recapture samples--problems in the estimation of hidden and elusive populations [comment]
Am J Public Health. 1994 Jul;84(7):1068-9. Unique Identifier : AIDSLINE MED/94288158
Neugebauer R; Wittes J; Gertrude H. Sergievsky Center, Faculty of Medicine, Columbia; University, New York, NY 10032.
Estimating the number of HIV-infected injection drug users in Bangkok: a capture--recapture method [see comments]
Am J Public Health. 1994 Jul;84(7):1094-9. Unique Identifier : AIDSLINE MED/94288164
Mastro TD; Kitayaporn D; Weniger BG; Vanichseni S; Laosunthorn V; Uneklabh T; Uneklabh C; Choopanya K; Limpakarnjanarat K; HIV/AIDS Collaboration, Bangkok, Thailand.
OBJECTIVES. The purpose of the study was to estimate the number of injection drug users infected with the human immunodeficiency virus (HIV) in Bangkok to allow planning for health services for this population. METHODS. A two-sample capture-recapture method was used. The first capture listed all persons on methadone t


Maternal-infant HIV transmission and circumstances of delivery [see comments]
Am J Public Health. 1994 Jul;84(7):1110-5. Unique Identifier : AIDSLINE MED/94288167
Kuhn L; Stein ZA; Thomas PA; Singh T; Tsai WY; Division of Epidemiology, Columbia University, New York, NY; 10032.
OBJECTIVES. Circumstances of delivery among children with acquired immunodeficiency syndrome (AIDS) were investigated to assess whether they were consistent with predictions that intrapartum factors affect the risk of maternal-infant human immunodeficiency virus (HIV) transmission. METHODS. Pediatric AIDS patients (ma


Substance use and HIV-related sexual behaviors among US high school students: are they related?
Am J Public Health. 1994 Jul;84(7):1116-20. Unique Identifier : AIDSLINE MED/94288168
Lowry R; Holtzman D; Truman BI; Kann L; Collins JL; Kolbe LJ; Division of Adolescent and School Health Centers for Disease; Control and Prevention, Atlanta, GA 30333.
OBJECTIVES. This study was undertaken to examine whether use of alcohol, cigarettes, marijuana, cocaine, and other illicit drugs is related to the likelihood of sexual behaviors that increase risk for human immunodeficiency virus (HIV) infection among youth. METHODS. The 1990 national Youth Risk Behavior Survey was us


HIV and AIDS in Africa. 1. Assisting those in the early stages of HIV infection [letter; comment]
Am J Public Health. 1994 Jul;84(7):1178; discussion 1179. Unique Identifier : AIDSLINE MED/94288183
Foster S
HIV and AIDS in Africa. Research priorities should not be limited to prophylaxis [letter; comment]
Am J Public Health. 1994 Jul;84(7):1178-9. Unique Identifier : AIDSLINE MED/94288184
Colebunders R; Van Renterghem H; Buve A
Increasing the effectiveness of HIV counseling [letter; comment]
Am J Public Health. 1994 Jul;84(7):1179-80. Unique Identifier : AIDSLINE MED/94288185
Hirano D; Slaughter FR; Sands L; Gellert GA
State health departments' role in AIDS policy: a clarification [letter; comment]
Am J Public Health. 1994 Jul;84(7):1180. Unique Identifier : AIDSLINE MED/94288186
Robins L; Backstrom C
Trends in condom use among nonmonogamous heterosexual men in The Netherlands [letter]
Am J Public Health. 1994 Jul;84(7):1184. Unique Identifier : AIDSLINE MED/94288191
Dingelstad A; de Vroome E; Paalman M; Sandfort T
The effect of the interaction of acyclovir with zidovudine on progression to AIDS and survival. Analysis of data in the Multicenter AIDS Cohort Study.
Ann Intern Med. 1994 Jul 15;121(2):100-8. Unique Identifier : AIDSLINE MED/94288372
Stein DS; Graham NM; Park LP; Hoover DR; Phair JP; Detels R; Ho M; Saah AJ; National Institute of Allergy and Infectious Diseases, National; Institutes of Health, Bethesda, Maryland.
OBJECTIVE: To examine the effect of acyclovir use on disease progression and survival in human immunodeficiency virus (HIV)-seropositive persons treated with zidovudine. SETTING: Four university-based or -affiliated clinics. DESIGN: Prospective cohort study of homosexual and bis


Superinfection with rifampin-isoniazid-streptomycin-ethambutol (RISE)-resistant tuberculosis in three patients with AIDS: confirmation by polymerase chain reaction fingerprinting.
Ann Intern Med. 1994 Jul 15;121(2):115-6. Unique Identifier : AIDSLINE MED/94288375
Horn DL; Hewlett D Jr; Haas WH; Butler WR; Alfalla C; Tan E; Levine A; Nayak A; Opal SM; Lincoln Medical and Mental Health Center, Bronx, New York.
Don't share razors or toothbrushes [letter; comment]
Ann Intern Med. 1994 Jul 15;121(2):153-4. Unique Identifier : AIDSLINE MED/94288392
Frothingham R
Helicobacter cinaedi-associated bacteremia and cellulitis in immunocompromised patients.
Ann Intern Med. 1994 Jul 15;121(2):90-3. Unique Identifier : AIDSLINE MED/94288394
Kiehlbauch JA; Tauxe RV; Baker CN; Wachsmuth IK; Centers for Disease Control and Prevention, Atlanta, Georgia.
OBJECTIVE: To define the clinical spectrum of illness associated with Helicobacter cinaedi infection in the United States and to determine associated epidemiologic risk factors and optimal laboratory methods for recovery of H. cinaedi. DESIGN: A retrospective epidemiologic study of 23


Neck swellings which mimic branchial cysts in HIV-positive patients [letter; comment]
Ann R Coll Surg Engl. 1994 May;76(3):212. Unique Identifier : AIDSLINE MED/94288490
Clunie GJ; Macleish DG
Demyelination and ethnicity: experience at the University of British Columbia Multiple Sclerosis Clinic with special reference to HTLV-I-associated myelopathy in British Columbian natives.
Ann Neurol. 1994;36 Suppl:S22-4. Unique Identifier : AIDSLINE MED/94288567
Oger J; Lai H; Multiple Sclerosis Clinic, University Hospital, University of; British Columbia, Vancouver, Canada.
Since its creation in 1980, the Multiple Sclerosis Clinic at the University of British Columbia has actively followed over 2,500 patients from the Canadian province of British Columbia (BC) who have clinically definite multiple sclerosis (MS). These patients include 2,496 European Caucasians from a BC population of 3,


The virology of demyelinating diseases.
Ann Neurol. 1994;36 Suppl:S54-60. Unique Identifier : AIDSLINE MED/94288574
Johnson RT; Department of Neurology, Johns Hopkins University School of; Medicine, Baltimore, MD.
Infectious agents have been postulated as causes of multiple sclerosis for over a century. The possible role of a virus or viruses is supported by data that (1) a childhood exposure is involved and viral infections may precipitate exacerbations of disease, (2) experimental infections in animals and natural infections


Absence of an association between antibodies to retroviral proteins and anticardiolipin antibody and/or lupus anticoagulant in systemic lupus erythematosus [letter]
Ann Rheum Dis. 1994 May;53(5):352-3. Unique Identifier : AIDSLINE MED/94288703
Matsuda J; Gotoh M; Gohchi K; Tsukamoto M; Saitoh N
Implications of generalists' slow adoption of zidovudine in clinical practice [see comments]
Arch Intern Med. 1994 Jul 11;154(13):1497-504. Unique Identifier : AIDSLINE MED/94288717
Markson LE; Cosler LE; Turner BJ; Center for Research in Medical Education and Health Care,; Jefferson Medical College, Philadelphia, Pa.
BACKGROUND: The lag time for adoption of new acquired immunodeficiency syndrome (AIDS) therapies into the clinical practices of different types of ambulatory care providers can be estimated from patient use of zidovudine therapy during the first few years after approval by the Food and Drug Administration. METHODS: We


Reporting recent sexual practices: gay men's disclosure of HIV risk by questionnaire and interview.
Arch Sex Behav. 1994 Apr;23(2):217-30. Unique Identifier : AIDSLINE MED/94288737
Siegel K; Krauss BJ; Karus D; Memorial Sloan-Kettering Cancer Center, New York, New York 10021.
AIDS-related research relies primarily on self-reports of sexual practices. Therefore, determining which data collection methods yield more candid information is critical. Data from a study of gay men s sexual adaptations to the AIDS epidemic provided an opportunity to explore the congruence of data collected using a


Neuropsychological characterization of the AIDS dementia complex and rationalization of a test battery.
Arch Neurol. 1994 Jul;51(7):689-95. Unique Identifier : AIDSLINE MED/94288755
Maruff P; Currie J; Malone V; McArthur-Jackson C; Mulhall B; Benson E; Neurophysiology and Neurovisual Research Unit, Mental Health; Research Institute of Victoria, Parkville, Australia.
OBJECTIVE: To define the neuropsychological deficits present in mild human immunodeficiency virus type 1 (HIV-1) associated with the acquired immunodeficiency syndrome (AIDS) dementia complex (ADC) and to develop a rational neuropsychological test battery for its diagnosis. DESIGN:


Choreoathetosis/ballismus associated with pentamidine-induced hypoglycemia in a patient with the acquired immunodeficiency syndrome.
Arch Neurol. 1994 Jul;51(7):723-5. Unique Identifier : AIDSLINE MED/94288760
Sweeney BJ; Edgecombe J; Churchill DR; Miller RF; Harrison MJ; Academic Department of Neurology, University College London; (England) Medical School.
OBJECTIVE: To describe the association between acute choreoathetosis/ballismus and hypoglycemia related to pentamidine therapy in a patient with the acquired immunodeficiency syndrome. DESIGN: A single case report. MEASURES: Clinical observation, laboratory analysis of blood and cerebrospinal fluid, and magnetic reson


HIV infection and the dentist. 1. The presence of HIV in saliva and its implications to dental practice [see comments]
Aust Dent J. 1994 Apr;39(2):67-72. Unique Identifier : AIDSLINE MED/94288779
Serb P; Yeung S; Department of Preventive Dentistry, University of Sydney.
The human immunodeficiency virus (HIV) has been detected in all body fluids. The presence and the detection of HIV virus in human saliva are reviewed. Modes of HIV transmission are discussed with particular reference to the possibility and risk of virus transmission via saliva. This risk is considered to be extremely


HIV infection and the dentist. 2. The diagnosis and management of gingivitis and periodontitis.
Aust Dent J. 1994 Apr;39(2):73-6. Unique Identifier : AIDSLINE MED/94288780
Yeung S; Serb P; Department of Preventive Dentistry, University of Sydney.
In HIV infected patients, a distinct form of gingivitis and periodontitis was reported recently. This paper reviews the clinical and microbiological features of these lesions and makes recommendations regarding their clinical management. The need for early treatment and control of periodontitis in HIV seropositive pat


Syringe and needle exchange to prevent HIV infection [letter; comment]
JAMA. 1994 Jun 15;271(23):1825; discussion 1826-7. Unique Identifier : AIDSLINE MED/94254186
Fernando D
Mycobacterium avium strains resistant to clarithromycin and azithromycin [letter; comment]
Antimicrob Agents Chemother. 1994 Mar;38(3):635. Unique Identifier : AIDSLINE MED/94263176
Wolinsky E
HIV-1 in newborns [letter; comment]
N Engl J Med. 1994 Jun 30;330(26):1905-6. Unique Identifier : AIDSLINE MED/94254985
Speiser DE; Wyler CA; Siegrist CA
Will education prevent human immunodeficiency virus infection? [letter; comment]
Arch Fam Med. 1994 Apr;3(4):309-10. Unique Identifier : AIDSLINE MED/94282346
Wetzel R
Molecular characterization of the env gene from a non-syncytium-inducing HIV-2 isolate (HIV-2ALI) [published erratum appears in AIDS Res Hum Retroviruses 1994 Apr;10(4):431]
AIDS Res Hum Retroviruses. 1994 Feb;10(2):223-4. Unique Identifier : AIDSLINE GENBANK/L25445
Taveira NC; Bex F; Burny A; Robertson D; Ferreira MO; Moniz-Pereira J; Department of Microbiology, Faculty of Pharmacy of Lisbon,; Portugal.
Selective effects of human immunodeficiency virus (HIV) gp120 on invertebrate neurons.
Cell Mol Neurobiol. 1993 Dec;13(6):569-77. Unique Identifier : AIDSLINE MED/94251782
Stefano GB; Sawada M; Smith EM; Hughes TK; Old Westbury Neuroscience Research Institute, State University of; New York at Old Westbury 11568-0210.
1. HIV gp120 selectively reduces the glutamate-induced inward current and the acetylcholine-induced outward current in specific and identified Aplysia neurons without affecting dopamine (DA)- and serotonin (5-HT)-induced responses. 2. gp120 specifically decreases DA levels without significantly altering norepinephrine


The Place of Oxygen Free Radicals in HIV Infections. Proceedings of a conference. Les Deux Alpes, France, January 1993.
Chem Biol Interact. 1994 Jun;91(2-3):77-224. Unique Identifier : AIDSLINE MED/94251849
Naive and memory T-cells in HIV-infected children [letter]
Eur J Pediatr. 1994 Apr;153(4):301. Unique Identifier : AIDSLINE MED/94252369
Duse M; Airo P; Prati E; Soresina A; Notarangelo LD; Cattaneo R; Ugazio AG
Treatment with interferon for genital HPV in HIV-positive and HIV-negative women.
Eur J Obstet Gynecol Reprod Biol. 1994 Feb;53(2):135-7. Unique Identifier : AIDSLINE MED/94252455
Semprini AE; Stillo A; Marcozzi S; Castagna C; Fiore S; Radaelli U; Department of Obstetrics and Gynecology, San Paolo Biomedical; Institute, University of Milan Medical School, Italy.
The administration of interferons can be resorted to, either on its own or in combination with physical destruction methods, when the extent of genital HPV is widespread. Extensive genital HPV involvement is often seen in HIV-positive patients as a consequence of their immunodeficiency. The extension of these lesions


[CD26--a new receptor for HIV (news)]
Fortschr Med. 1994 Mar 30;112(9):14. Unique Identifier : AIDSLINE MED/94252650
The neglected global tuberculosis problem: a report of the 1992 World Congress on Tuberculosis.
J Infect Dis. 1994 Jun;169(6):1189-96. Unique Identifier : AIDSLINE MED/94253574
Snider DE Jr; La Montagne JR; National Center for Prevention Services, Centers for Disease; Control and Prevention, Atlanta, Georgia 30333.
Tuberculosis is the single leading cause of death from any single infectious agent. A world congress on tuberculosis was held to highlight the problem and to discuss recent scientific advances and global strategies for prevention and control. About one-third of the world population is latently infected with Mycobacter


Characteristics of long-term asymptomatic infection with human immunodeficiency virus type 1 in men with normal and low CD4+ cell counts.
J Infect Dis. 1994 Jun;169(6):1236-43. Unique Identifier : AIDSLINE MED/94253580
Keet IP; Krol A; Klein MR; Veugelers P; de Wit J; Roos M; Koot M; Goudsmit J; Miedema F; Coutinho RA; Municipal Health Service, Department of Public Health and; Environment, Amsterdam, Netherlands.
From a cohort study of homosexual men in Amsterdam, 61 human immunodeficiency virus (HIV)-infected men who had remained asymptomatic for at least 7 years were identified. In a nested case control study, these men were compared with 142 men who progressed symptomatic HIV infection (CDC class IV) within 7 years, regardi


Effect of immunization with inactivated gp120-depleted human immunodeficiency virus type 1 (HIV-1) immunogen on HIV-1 immunity, viral DNA, and percentage of CD4 cells.
J Infect Dis. 1994 Jun;169(6):1256-64. Unique Identifier : AIDSLINE MED/94253583
Trauger RJ; Ferre F; Daigle AE; Jensen FC; Moss RB; Mueller SH; Richieri SP; Slade HB; Carlo DJ; Immune Response Corporation, Carlsbad, California 92008.
A 1-year study measured the effect of administration of an inactivated human immunodeficiency virus type 1 (HIV-1) immunogen in incomplete Freund s adjuvant (IFA) on HIV-1-specific immunity and viral burden in asymptomatic HIV-1-infected patients. A total of 103 patients were enrolled in this double-blind, randomized


Human herpesvirus 6 DNA in blood cells of human immunodeficiency virus-infected men: correlation of high levels with high CD4 cell counts.
J Infect Dis. 1994 Jun;169(6):1342-5. Unique Identifier : AIDSLINE MED/94253597
Fairfax MR; Schacker T; Cone RW; Collier AC; Corey L; Department of Laboratory Medicine, University of Washington; School of Medicine, Seattle 98144.
The relationship between human herpesvirus 6 (HHV-6) and the progression of human immunodeficiency virus type 1 (HIV-1) infection to AIDS was evaluated using the polymerase chain reaction to quantitate HHV-6 genome equivalents in peripheral blood mononuclear cells (PBMC) and saliva of 32 HIV-1-seropositive men. Unlike


Zidovudine and interferon-alpha combination therapy versus zidovudine monotherapy in subjects with symptomatic human immunodeficiency virus type 1 infection.
J Infect Dis. 1994 Jun;169(6):1351-5. Unique Identifier : AIDSLINE MED/94253599
Frissen PH; van der Ende ME; ten Napel CH; Weigel HM; Schreij GS; Kauffmann RH; Koopmans PP; Hoepelman AI; de Boer JB; Weverling GJ; et al; Department of Internal Medicine, Academic Medical Center,; Amsterdam, Netherlands.
Forty-five subjects with symptomatic human immunodeficiency virus type 1 (HIV-1) infection, CD4+ lymphocyte counts of > or = 150 x 10(6)/L, and Karnofsky scores > or = 60 were enrolled in a multicenter, randomized, controlled trial that compared zidovudine monotherapy and


HIV-1 variants: yet another challenge to public health [comment]
Lancet. 1994 Jun 4;343(8910):1376. Unique Identifier : AIDSLINE MED/94254516
Dondero TJ; Hu DJ; George JR; Division of HIV/AIDS, Center for Infectious Diseases, Centers for; Disease Control and Prevention, Atlanta, Georgia.
HIV-1/HIV-2 seronegativity in HIV-1 subtype O infected patients [see comments]
Lancet. 1994 Jun 4;343(8910):1393-4. Unique Identifier : AIDSLINE MED/94254523
Loussert-Ajaka I; Ly TD; Chaix ML; Ingrand D; Saragosti S; Courouce AM; Brun-Vezinet F; Simon F; Virology Department, Bichat-Claude Bernard Hospital, Paris,; France.
Nine patients with atypical HIV-1 western blot profiles were diagnosed as having HIV-1 subtype O infection. All the patients were living in France ; eight originated from Cameroon and one from France. Lymphocyte DNA amplification by the polymer


US tuberculosis figures [news]
Lancet. 1994 Jun 4;343(8910):1420. Unique Identifier : AIDSLINE MED/94254533
Horton R
Emerging and new infectious diseases [news]
Lancet. 1994 Jun 4;343(8910):1423. Unique Identifier : AIDSLINE MED/94254536
McConnell J
Antiretroviral prevention of HIV perinatal transmission [letter]
Lancet. 1994 Jun 4;343(8910):1429-30. Unique Identifier : AIDSLINE MED/94254546
Lallemant M; Le Coeur S; Tarantola D; Mann J; Essex M
HIV lookback: a forward glance? [letter; comment]
Lancet. 1994 Jun 4;343(8910):1430. Unique Identifier : AIDSLINE MED/94254547
Gill ON; Heptonstall J; Noone A; Mortimer J
Polymerase chain reaction to diagnose HIV-1 [letter]
Lancet. 1994 Jun 4;343(8910):1431. Unique Identifier : AIDSLINE MED/94254548
Tosswill JH; Barlow KL; Parry JV; Clewley JP
Multidrug-resistant tuberculosis and AIDS [letter]
Lancet. 1994 Jun 4;343(8910):1431-2. Unique Identifier : AIDSLINE MED/94254549
Sharp V; Chiliade P; Sepkowitz KA
The lucky ones. How do some HIV-positive people avoid getting AIDS? [news]
Sci Am. 1994 May;270(5):20, 24, 28. Unique Identifier : AIDSLINE MED/94255749
Beardsley T
AIDS vaccines. Immune Response Corp.--take two [news]
Science. 1994 Jun 3;264(5164):1402. Unique Identifier : AIDSLINE MED/94255759
Cohen J
[Infection by human T-cell lymphotropic virus type I/II in polytransfused patients in the state of Yucatan, Mexico]
Sangre (Barc). 1994 Feb;39(1):45-8. Unique Identifier : AIDSLINE MED/94255833
Gonzalez-Martinez P; Castro-Sansores C; Vivas-Rosel ML; Gongora-Biachi RA; Centro de Investigaciones Regionales, Dr. Hideyo Noguchi,; Universidad Autonoma de Yucatan, Mexico.
The relationship between several disorders, including adult T-cell leukaemia, and HTLV I/II virus infection has been clearly demonstrated. In order to assess the prevalence of such viral infection in a group of multiple-transfusion patients in the State of Yucatan, Mexico , a study


[Gastrointestinal manifestations of HIV infection]
Z Gastroenterol. 1994 Mar;32(3):174-81. Unique Identifier : AIDSLINE MED/94256165
Schneider T; Ullrich R; Zeitz M; Abteilung fur Innere Medizin mit Schwerpunkt Gastroenterologie,; Medizinische Klinik und Poliklinik, Klinikum Steglitz der Freien; Universitat Berlin.
The intestinal (in particular rectal) mucosa is the main portal of entry for HIV in homosexual men, who represent the vast majority of HIV-infected patients in Europe and North America. There are several possibilities for HIV to reach the CD4-positive T cells, macrophages and follicular-dendritic cells in the intestin


Crohn's ileitis in a patient with longstanding HIV infection [see comments]
Am J Gastroenterol. 1994 Jun;89(6):937-9. Unique Identifier : AIDSLINE MED/94256472
Bernstein BB; Gelb A; Tabanda-Lichauco R; Division of Gastroenterology, Beth Israel Medical Center, New; York, N.Y.
The differential diagnosis of diarrhea in patients infected with HIV is broad, and includes a variety of bacterial, viral, and parasitic pathogens, as well as malignancies including lymphoma and Kaposi s sarcoma. Idiopathic non-specific inflammatory bowel disease rarely occurs in association with HIV infection. A rece


CD26: a surface protease involved in T-cell activation.
Immunol Today. 1994 Apr;15(4):180-4. Unique Identifier : AIDSLINE MED/94257126
Fleischer B; Dept of Medical Microbiology and Immunology,; Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany.
CD26 is a proteolytic enzyme (dipeptidylpeptidase IV) with a wide tissue distribution and a unique specificity. Recent developments indicate that CD26 is a multifunctional molecule that may have important functions in the immune system. Here, Bernhard Fleischer reviews the current knowledge of CD26 and discusses the p


In vitro lymphocyte proliferative response to HIV-1 p24 is associated with a lack of CD4+ cell decline [letter]
AIDS Res Hum Retroviruses. 1994 Feb;10(2):113-4. Unique Identifier : AIDSLINE MED/94257314
Pontesilli O; Carlesimo M; Varani AR; Ferrara R; D'Offizi G; Aiuti F
HIV antigen-reactive T cells detected by antigen-induced interferon gamma secretion.
AIDS Res Hum Retroviruses. 1994 Feb;10(2):115-20. Unique Identifier : AIDSLINE MED/94257315
Lolli F; Chen LB; Sundqvist VA; Link H; Holmberg V; Wahren B; Department of Virology, National Bacteriological Laboratory,; Solna, Stockholm, Sweden.
The T cell repertoire to human immunodeficiency virus (HIV) was studied in HIV-infected patients of different clinical stages by the detection and enumeration of cells that secreted interferon gamma (IFN-gamma) in short-term cultures of blood mononuclear cells after stimulation in vitro with the HIV recombinant antige


Beta-2 microglobulin as a predictor of prognosis in HIV-infected men with haemophilia: a proposed strategy for use in clinical care.
Br J Haematol. 1994 Feb;86(2):366-71. Unique Identifier : AIDSLINE MED/94257499
Sabin CA; Phillips AN; Lee CA; Elford J; Timms A; Bofill M; Janossy G; Department of Public Health and Primary Care, Royal Free Hospital; School of Medicine, London.
Whilst the prognostic value of serum beta-2 microglobulin (s-beta 2m) is well documented, the lack of a simple strategy for its use means that it is rarely ever measured in clinical practice. The prognosis associated with s-beta 2m at two different points in HIV infection, as defined by the CD4 count, was studied in a


Correlation of body mass index with urinary neopterin in individuals infected with human immunodeficiency virus.
Int Arch Allergy Immunol. 1994;104(2):150-4. Unique Identifier : AIDSLINE MED/94257967
Zangerle R; Sarcletti M; Gallati H; Reibnegger G; Wachter H; Fuchs D; Department of Dermatology and Venerology, University of; Innsbruck, Austria.
We assessed correlations between body mass index and plasma lipids, immune activation markers and the CD4+ T-cell count. The subjects of this cross-sectional study were randomly selected and comprised all those who attended the AIDS Out-Patient Clinic at the University Hospital in Innsbruck in March and April 1992. Pa


Lymphokine-activated killer (LAK) precursor cell activity is present in infused peripheral blood stem cells and in the blood after autologous peripheral blood stem cell transplantation.
Bone Marrow Transplant. 1994 Mar;13(3):311-6. Unique Identifier : AIDSLINE MED/94258093
Neubauer MA; Benyunes MC; Thompson JA; Bensinger WI; Lindgren CG; Buckner CD; Fefer A; Division of Oncology, University of Washington, Seattle 98195.
Immunotherapy with interleukin-2 ( IL-2 ) early after peripheral blood stem cell transplantation (PBSCT) is being considered as a potential way to eradicate minimal residual disease. The aim of this study was to determine whether lymphocytes which can acquire lymphokine-


Modulation of HTLV-II-associated spontaneous lymphocyte proliferation by beta 2 integrin CD11a/CD18 involves interaction with its cognate ligand, CD54.
Cell Immunol. 1994 Jun;156(1):113-23. Unique Identifier : AIDSLINE MED/94258707
Dezzutti CS; Rudolph DL; Dhawan S; Lal RB; Retrovirus Diseases Branch, CDC, Atlanta, Georgia 30333.
In vitro culture of lymphocytes from persons infected by human T-lymphocyte virus type II (HTLV-II) results in spontaneous proliferation in the absence of any exogenous stimuli. The present investigation examined the role of integrin molecules in spontaneous lymphocyte proliferation (SLP) in persons infected with HTLV


HIV-1 and reproductive health in Africa.
Int J Gynaecol Obstet. 1994 Feb;44(2):107-12. Unique Identifier : AIDSLINE MED/94259205
Temmerman M; Chomba EN; Piot P; Department of Medical Microbiology, University of Nairobi, Kenya.
Factors predictive of maternal-fetal transmission of HIV-1. Preliminary analysis of zidovudine given during pregnancy and/or delivery [see comments]
JAMA. 1994 Jun 22-29;271(24):1925-30. Unique Identifier : AIDSLINE MED/94260675
Boyer PJ; Dillon M; Navaie M; Deveikis A; Keller M; O'Rourke S; Bryson YJ; Department of Obstetrics and Gynecology, UCLA School of Medicine.
OBJECTIVE--To assess maternal risk factors potentially influencing vertical transmission of human immunodeficiency virus, type 1 (HIV-1), including maternal CD4 cell count; presence of immune complex dissociated (ICD) p24 antigen; maternal zidovudine therapy during pregnancy and/or delivery; complications of pregnancy


Caesarean section and risk of vertical transmission of HIV-1 infection. The European Collaborative Study [see comments]
Lancet. 1994 Jun 11;343(8911):1464-7. Unique Identifier : AIDSLINE MED/94260786
Indirect evidence suggests that a significant proportion of vertical transmission of HIV infection occurs late in pregnancy or during delivery. Caesarean section, therefore, may protect the fetus from infection. We looked at 1254 HIV-infected mothers and their children and the effects of different modes of delivery on


Childhood tuberculosis in the Bronx, New York.
Lancet. 1994 Jun 11;343(8911):1482-5. Unique Identifier : AIDSLINE MED/94260792
Drucker E; Alcabes P; Bosworth W; Sckell B; Department of Epidemiology and Social Medicine, Monteflore; Medical Center/Albert Einstein College of Medicine, Bronx, New; York 10467-2490.
The resurgence of tuberculosis (TB) in New York City in the period 1978-92 has been closely linked to the AIDS epidemic but the increase of active TB in areas of urban poverty also implies increased community exposure. We have examined the ecological relation between community rates of AIDS and residential crowding an


Deaths in US fialuridine trial [news]
Lancet. 1994 Jun 11;343(8911):1494-5. Unique Identifier : AIDSLINE MED/94260796
Brahams D
Personal screening for HIV in developing countries [letter]
Lancet. 1994 Jun 11;343(8911):1506. Unique Identifier : AIDSLINE MED/94260817
Frerichs RR
Immune activation, a co-factor for HIV transmission in Thailand? [letter; comment]
Lancet. 1994 Jun 11;343(8911):1506-7. Unique Identifier : AIDSLINE MED/94260818
Kalinkovich A; Maayan S; Weisman Z; Harpaz N; Bentwich Z
Phenotype switch and activation of T lymphocytes in patients with allergic rhinitis.
ORL J Otorhinolaryngol Relat Spec. 1994 May-Jun;56(3):166-72. Unique Identifier : AIDSLINE MED/94261378
Karlsson MG; Hellquist HB; Department of Pathology, Orebro Medical Center Hospital, Sweden.
The peripheral blood of 17 patients with seasonal allergic rhinitis (birch pollen) and of 10 healthy subjects were analysed before and during a provocation study in the non-pollen season as well as during the pollen season. Analytical flow cytometry comprised a panel of monoclonal antibodies investigating helper/suppr


Estimation of time since infection using longitudinal disease-marker data.
Stat Med. 1994 Feb 15;13(3):231-44. Unique Identifier : AIDSLINE MED/94261762
Dubin N; Berman S; Marmor M; Tindall B; Des Jarlais D; Kim M; Department of Environmental Medicine, New York University Medical; Center, NY 10016.
We propose a method to estimate the usually unknown time since infection for individuals infected with human immunodeficiency virus type 1 (HIV-1). If we assume the time since infection has an exponential prior distribution, then under the model the conditional distribution of time since infection, given the CD4 level


Foscarnet for suppression of human immunodeficiency virus replication.