1994

Nutrition for persons with HIV infection. [videorecording]: [Michigan] : University of Michigan, c1991 1 videocassette (19 min., 23 sec.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9430598; Bridges T; Church MJ; Collins T
Clinical update on HIV infection : recorded at DDW 1994 in New Orleans. [sound recording]: [Thorofare, N.J.] : American Gastroenterology [i.e. Gastroenterological] Association, [1994] 1 sound cassette (90 min.) : analog (AGA clinical symposium) Unique Identifier : AIDSLINE AV/9435489
Controlling your risks : HIV in the research laboratory : a video. [videorecording]: [Bethesda, Md.] : Howard Hughes Medical Institute, c1994 1 videocassette (28 min.) : sd., col. with b&w ; 1/2 in Unique Identifier : AIDSLINE AV/9433966; Schumann W; Barkley WE; Martin MA; (Producer) Designed for laboratory workers at risk of occupational exposure to HIV, the video promotes laboratory safety and highlights the practices and equipment used to protect against HIV transmission in the research environment. Thoughts of several prominent researchers, including Harold Varmus and Tony Fauci,
AIDS : knowledge, attitudes, and sexual practices among Hispanics in Chicago : results of a 1988 city-wide survey : preliminary analyses.: Chicago : The Alliance, [1988] 107, [106] leaves : ill Unique Identifier : AIDSLINE CAT/9415120
A:five year medium term plan for the prevention and control of AIDS in Malawi : (1989-1993).: Lilongwe, Malawi : National AIDS Control Programme, Ministry of Health, [1989] 128 p. : ill Unique Identifier : AIDSLINE CAT/9405518
Recommendations for prevention of HIV transmission in health care settings.: Education Services. HIV/AIDS and Infectious Diseases [Olympia, Wash.?] : HIV/AIDS and Infectious Diseases, Office of Prevention and Education Services, Washington State Dept. of Health, [1990?] 25, x p (DOH Pub. ; 410-004) Unique Identifier : AIDSLINE CAT/9431422
Malawi, HIV treatment guidelines for adults and children : national guidelines.: [Malawi? : s.n., 1991] 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9414530
Dragon within the gates : the once and future AIDS epidemic. 1st ed.: New York : Carroll & Graf Publishers, 1992 272 p Unique Identifier : AIDSLINE CAT/9405648; Joseph SC
[Drogues illicites et attitudes face au SIDA : resultats d'une enquete epidemiologique realisee dans le Sud-Haute-Marne.]: Paris : INSERM, c1992 87 p. : ill (Analyses et prospective) Unique Identifier : AIDSLINE CAT/9407705; Choquet M
Getting to the point : HIV, drug abuse, and syringe exchange in the United States.: Denver, Colo. (1560 Broadway, Suite 700, Denver 80202) : National Conference of State Legislatures, 1992 17 p (State legislative report ; vol. 17, no. 14) Unique Identifier : AIDSLINE CAT/9405641; Hooker TA
Legal issues in pediatric HIV practice : a handbook for health care providers.: Newark, NJ : National Pediatric HIV Resource Center, [c1992] 1 v. (various pagings) Unique Identifier : AIDSLINE CAT/9415282
The:anarchist AIDS medical formulary : a guide to guerrilla immunology.: Berkeley, Calif. : North Atlantic Books, c1993 xv, 155 p. : ill Unique Identifier : AIDSLINE CAT/9423638; Caulfield CR; Goldberg B
HIV molecular organization, pathogenicity, and treatment.: Amsterdam ; New York : Elsevier, 1993 viii, 386 p. : ill Unique Identifier : AIDSLINE CAT/9423567; Morrow J; Haigwood NL
Sexuality, politics, and AIDS in Brazil : in another world?.: London ; Washington, D.C. : Falmer Press, 1993 xiv, 168 p (Social aspects of AIDS) Unique Identifier : AIDSLINE CAT/9417494; Daniel H; Parker RG
Sixth research project on AIDS : progress report : Orbetello (GR), 19-23 June 1993.: Roma : Ministerio della sanita, Istituto superiore di sanita, 1993 368 p. : ill (Rapporti ISTISAN, ISSN 0391-1675 ; ISTISAN 93/32) Unique Identifier : AIDSLINE CAT/9433707
AIDS and behavior : an integrated approach.: Washington, D.C. : National Academy Press, 1994 xvii, 338 p. : ill Unique Identifier : AIDSLINE CAT/9434637; Auerbach JG; Wypijewska C; Brodie HK; Mental Health Issues in AIDS Research
Treating AIDS with Chinese medicine.: Berkeley, Calif. : Pacific View Press, c1994 xx, 364 p Unique Identifier : AIDSLINE CAT/9431127; Ryan MK; Shattuck AD
Understanding the possible : policies for the prevention of HIV in South Africa.: Johannesburg : Centre for Health Policy, University of the Witwatersrand : Medical Research Council, [1994?] 27 p. : ill Unique Identifier : AIDSLINE CAT/9431805; Schneider H; Steinberg M; IJsselmuiden C
Dental management of patients with HIV.: Chicago : Quintessence Pub. Co., c1994 319 p. : ill Unique Identifier : AIDSLINE CAT/9435285; Glick M
HIV and your child.: Rockville, MD (Executive Office Center, Suite 501, 2101 E. Jefferson St., Rockville 20852) : U.S. Dept. of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, [1994] 21 p. : ill (Clinical practice guideline ; no. 7. Consumer guide) Unique Identifier : AIDSLINE CAT/9423491
HIV infection in women.: New York : Raven Press, c1995 xiv, 328 p. : ill Unique Identifier : AIDSLINE CAT/9434906; Minkoff HL; DeHovitz JA; Duerr A
Gynecologic oncology. 2nd ed.: Gynecologic Oncology. 2nd Ed. Coppleson M, ed. New York, Churchill Livingstone, 2 vol., 1525 p., 1992.. Unique Identifier : AIDSLINE ICDB/94696705; Anonymous; No affiliation given; Rapid advances in both scientific and clinical aspects of the specialty in the 10 yr since the 1st edition of Gynecologic Oncology mandated the present 2nd edition which, because of this growth, contains an additional 12 chapters. The bulk of the book deals in detail with the gynecologic malignancies, presenting clini
Regulation of transcription of the tax transgene and tax-induced genes in tumor cell lines of the LTR-tax transgenic mouse.: Diss Abstr Int [B]; 53(9):4501 1993. Unique Identifier : AIDSLINE ICDB/94690786; Fontes JD; Univ. of California, Davis; The LTR-tax transgenic mouse develops peripheral neurofibromas as its primary pathologic feature. An in vitro cell line (Px-1 cells) derived from one of these tumors provides an excellent model for the study of tax-driven neoplasia. Using these cells, the role of tax in the trans-activation of cellular genes and the t
Alternative dna structures in topoisomerase II-DNA interactions.: Diss Abstr Int [B]; 53(9):4481 1993. Unique Identifier : AIDSLINE ICDB/94690788; Howard MT; Univ. of North Carolina at Chapel Hill; The type II DNA topoisomerases are enzymes that can change the topological state of DNA. This is accomplished by passing DNA strands through each other via a transient break in the helix. The result of this reaction is to relax or introduce DNA supercoils and to resolve knotted or catenated DNAs. Topoisomerase activit
Dietary carotenoids, cigarette smoking and Kaposi's sarcoma in the San Francisco Men's Health Study.: Diss Abstr Int [B]; 53(9):4596 1993. Unique Identifier : AIDSLINE ICDB/94690808; Duncan DM; Univ. of California, Berkeley; This study utilized data from the San Francisco Men s Health Study (SFMHS) to explore the relationship between dietary intake and subsequent development of Kaposi s sarcoma (KS) in a cohort of men at high risk for acquired immunodeficiency syndrome (AIDS). The SFMHS is a prospective study observing the natural history
Sequence analysis of a viral gene found within the central nervous system of patients with human T-cell lymphotropic virus type I-associated disease.: Diss Abstr Int [B]; 53(10):5067 1993. Unique Identifier : AIDSLINE ICDB/94690940; Maroushek SR; Univ. of Minnesota; Human T-cell lymphotropic virus type I (HTLV-I) is a type C retrovirus endemic to portions of Japan , the Caribbean, Africa, South America, and the United States . Although infection with HTLV-I causes predominantly asymptomatic infections, HTLV-I is t
The epidemiology of hepatitis C virus transmission.: Diss Abstr Int [B]; 53(10):5160 1993. Unique Identifier : AIDSLINE ICDB/94690954; Osmond DH; Univ. of California, Berkeley; Hepatitis C virus (HCV) is a newly identified virus that is the most important agent of non-A non-B hepatitis and is associated with cirrhosis and hepatocellular carcinoma. HCV is readily transmitted intravenously by blood and blood products, but preliminary reports have disagreed about the importance of perinatal and
An epidemiological approach to the etiology of Hodgkin's disease.: Diss Abstr Int [C]; 54(2):506 1993. Unique Identifier : AIDSLINE ICDB/94696103; Merk KF; Karolinska Institutet, Sweden; In focus of this thesis were factors of potential importance for the development and outcome of Hodgkin s disease (HD), especially the cause of the immunodeficiency (ID) and its relation to HD. The epidemiological features of HD in Cuba and Sweden
Function of the human T-cell leukemia virus Rex response element in viral RNA processing.: Diss Abstr Int [B]; 53(12):6110 1993. Unique Identifier : AIDSLINE ICDB/94696128; Ahmed YF; Duke Univ.; The type I human T cell leukemia virus (HTLV-I) is the etiologic agent of an aggressive malignancy of human CD4+ T lymphocytes known as adult T cell leukemia. In addition to the gag, pol and env genes present in all replication-competent retroviruses, HTLV contains two additional regulatory genes tax and rex. The HTLV
Analysis of three distinct stages of replication in human retroviruses.: Diss Abstr Int [B]; 53(12):6113 1993. Unique Identifier : AIDSLINE ICDB/94696141; Hammes SR; Duke Univ.; The type 1 human immunodeficiency and human T-cell leukemia viruses (HIV-1 and HTLV-I, respectively) use many mechanisms at various stages throughout their life cycles to regulate replication. Three of these processes were examined in detail in order to better understand some of the complexities of this regulation. Th
Increased survival and development of lymphoma in murine immunodeficiency disease (MAIDS): effects of lithium and magnesium in vivo (Meeting abstract).: FASEB J; 7(4):A692 1993. Unique Identifier : AIDSLINE ICDB/94696889; Gallicchio VS; Cibull ML; Hughes NK; Tse KF; Univ. of Kentucky and Veterans Administration Medical Centers,; Lexington, KY 40536; Murine immunodeficiency disease (MAIDS) induced with LP-BM5 strain of MuLV is a disease that shows many similarities to human HIV-infection. Lithium (Li) influences many aspects of immunohematopoietic cellular proliferation and differentiation and is an antagonist to magnesium (Mg) dependent reactions. We describe her
Cationic liposomes for direct gene transfer in therapy of cancer and other diseases (Meeting abstract).: Gene Therapy for Neoplastic Diseases. June 26-29, 1993, Washington, DC, A5, 1993.. Unique Identifier : AIDSLINE ICDB/94698152; Huang L; Gao X; Farhood H; Son K; Dept. of Pharmacology, Univ. of Pittsburgh Sch. of Medicine,; Pittsburgh, PA; Cationic liposomes can mediate efficient delivery of DNA and DNA/protein complex to mammalian cells in vitro and in vivo. Cationic cholesterol derivatives mixed with phosphatidylethanolamine and sonicated to form small unilamellar vesicles can complex with DNA and mediate the entry into the cytosol from the endosome c
The retroviral life cycle and safety considerations for retroviral mediated gene therapy (Meeting abstract).: Gene Therapy for Neoplastic Diseases. June 26-29, 1993, Washington, DC, A7, 1993.. Unique Identifier : AIDSLINE ICDB/94698154; Boris-Lawrie K; Temin HM; McArdle Lab. for Cancer Res., Univ. of Wisconsin, Madison, WI; The life cycle of retroviruses makes them uniquely suited as vectors for gene therapy. Safety is the primary consideration when designing retroviral vectors and helper cells. Retroviral vectors used for gene therapy are based on simpler retroviruses (SRV), which do not cause disease in humans and ungulates. Retroviral
HTLV-I and -II natural history and disease associations (Meeting abstract).: International Association for Comparative Research on Leukemia and Related Diseases, 16th Symposium. July 11-16, 1993, Montreal, Quebec, Canada, A52, 1993.. Unique Identifier : AIDSLINE ICDB/94698650; Blattner WA; Viral Epidemiology Section, NCI, Bethesda, MD; In 1980 HTLV-I and in 1982 HTLV-II were isolated. Considerable progress has been gained in defining the natural history of HTLV-I, while for HTLV-II progress has been slow. Recent studies have helped to clarify mechanisms of virus transmission. Breast milk feeding is the major route for transmission of HTLV-I in the f
HTLV-I LTR 21 bp repeat-specific and neuroglial cell-specific DNA-protein complexes (Meeting abstract).: International Association for Comparative Research on Leukemia and Related Diseases, 16th Symposium. July 11-16, 1993, Montreal, Quebec, Canada, A54, 1993.. Unique Identifier : AIDSLINE ICDB/94698652; Tillmann M; Hinkel R; Wigdahl B; Dept. of Microbiology and Immunology, Pennsylvania State Univ.; Coll. of Medicine, Hershey, PA; Human T-cell leukemia virus type I (HTLV-I) is an etiologic agent of adult T-cell leukemia and a chronic neurologic disorder, tropical spastic paraparesis. An HTLV-I-encoded protein, Tax, is capable of transcriptionally trans-activating HTLV-I by interacting with specific sequences in the HTLV-I long terminal repeat (
Molecular and biochemical effects of novel drugs derived from photoactivated compounds for chemotherapy of leukemia (Meeting abstract).: International Association for Comparative Research on Leukemia and Related Diseases, 16th Symposium. July 11-16, 1993, Montreal, Quebec, Canada, A60, 1993.. Unique Identifier : AIDSLINE ICDB/94698657; Gulliya KS; Sharma RK; Wiggs RB; Baylor Univ. Medical Center, Baylor Res. Inst., 3812 Elm, Dallas,; TX 75226; The novel technology termed preactivation in which optical radiation is used to produce heretofore unknown therapeutic compounds has been reported (Gulliya et al, 1991). Because of this invention, photoactive compound-derived photoproducts can now be used, for the first time, for systemic therapy (independent of lig
A Phase I study of an angiogenesis inhibitor, TNP-470 (AGM-1470), administered to patients (pts) with HIV-associated Kaposi's sarcoma (KS) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A8 1994. Unique Identifier : AIDSLINE ICDB/94600005; Pluda JM; Wyvill K; Figg WD; Whitcup SM; Lietzau J; Saville MW; Cohen R; Feigal E; Parks D; Foli A; et al; NCI, Bethesda, MD; The fumagillin analogue TNP-470 is a potent inhibitor of angiogenesis in vitro (Ingber, et al Nature 348, 555, 1990). Anti-tumor inhibitory activity in animal models has been shown to be dose- but not schedule-dependent. We have found that TNP-470 inhibits in vitro KS-derived spindle cell proliferation (Saville, et al
Novel combination chemotherapy for HIV-related non-Hodgkin's lymphoma (HIV-NHL) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A13 1994. Unique Identifier : AIDSLINE ICDB/94600010; Sawka C; Shepherd F; Brandwein J; Berinstein N; Singer J; Canadian HIV Trials Network, Vancouver, Canada; Conventional-dose chemotherapy is poorly tolerated in HIV-NHL; even low-dose programs including our half-dose weekly drug program (Leukemia and Lymphoma 1992, 8:213-220) have been associated with significant febrile neutropenia rates. We designed a novel chemotherapy program to attempt to reduce this complication whil
A trial of Paclitaxel (TAXOL) in patients with HIV-associated Kaposi's sarcoma (KS) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A20 1994. Unique Identifier : AIDSLINE ICDB/94600017; Saville MW; Lietzau J; Wilson W; Pluda J; Bailey J; Cohen R; Feigal E; Broder S; Yarchoan R; NCI, Bethesda, MD 20892; KS is a frequent cause of severe morbidity and death in patients with human immunodeficiency virus (HIV) infection. Current therapies are often poorly tolerated, and new drugs are needed for this condition. It has been observed that inhibitors of microtubule assembly are active against KS, and this led us to consider
Epidemiological, virological and clinicopathological data from 114 patients (pts) with Hodgkin's disease and HIV infection (HD-HIV) evidence of significant relation to Epstein-Barr virus (EBV), increase of mixed cellularity (MC) and lymphocyte depletion (LD) subtypes and feasibility of combined treatment with chemotherapy (CT) and zidovudine (AZT) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A22 1994. Unique Identifier : AIDSLINE ICDB/94600019; Errante D; Tirelli U; Serraino D; Boiocchi M; Carbone A; Italian Cooperative Study Group on AIDS and Tumors (GICAT),; C.R.O. Aviano, Italy; Since November 1986, 114 cases (103 m, 11 f) of HD-HIV have been collected by the GICAT. The median age was 29 years (19-57), 80% were IVDU in accordance to the overall epidemiology of HIV infection in Italy . At the diagnosis of HD, 17% of pts had AIDS, 22% ARC, 29% PGL and 34% were
Primary central nervous system lymphoma (PCNSL) in Saskatchewan (SK): A 30-year trend (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A513 1994. Unique Identifier : AIDSLINE ICDB/94600509; Williams CK; Allan Blair Memorial Clinic, Saskatchewan Cancer Foundation,; Regina, SK, S4T 7T1, Canada; The incidence of PCNSL has recently been increasing world-wide primarily among AIDS patients, but also in immune competent population (ICP). The epidemiology of PCNSL in SK, a region of Canada where AIDS s impact on community health has been negligible, was evaluated by identifying
Changing trends of primary malignant neoplasms (PMN) in children (C) 0-15 yr and young adults (YA) 16-35 yr (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A535 1994. Unique Identifier : AIDSLINE ICDB/94600531; Samuel J; Goyal V; Cook County Hosp., Chicago, IL 60612; From January 1984 to December 1991, 7949 patients (pts) with cancer were reported in the tumor registry. 822 pts (10%) were up to age 35, of which 90 (10%) were in C, females (54%). The common PMN were cervix 23%, lymphoma and leukemia (L) 18%, Kaposi s Sarcoma (KS) (10%), breast 6% and brain 6%. In C, it was L 36% fo
Immunologic correlates in patients (pts) with head and neck cancer (SCCHN) treated with interferon alpha (IFN): association between natural killer cell (NK) activity and prolonged survival (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A900 1994. Unique Identifier : AIDSLINE ICDB/94600896; Vlock D; Andersen J; Whiteside T; Herberman R; Kirkwood J; Adams G; Brigham and Women's Hospital, Harvard Medical School, Boston, MA; 02115; 71 pts with recurrent or metastatic SCCHN were entered onto a phase II noncomparative randomized trial of IFN at 2 dosage schedules (EST P-Z386): low dose IFN, 6 x 10(6) U/m2 daily x 3 every 4 wk or high dose IFN, 12 x 10(6) U/m2, 3x/wk (Proc ASCO, 10:205). While the overall response rates were low (3 CRs) disease sta
Epstein-barr virus-associated lymphoproliferative disease (EBV-LPD) in the severe combined immune deficient human/mouse model: prevention with low dose interleukin-2 suppresses production of human interleukin-6 and interleukin-10 (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A969 1994. Unique Identifier : AIDSLINE ICDB/94600965; Baiocchi R; Sullivan L; Tan J; Narula S; Caligiuri M; Dept of Medicine, Roswell Park Cancer Inst., Buffalo, NY 14263; When severe combined immune deficient (SCID) mice are reconstituted with human PBL (hu-PBL-SCID) from individuals seropositive for Epstein-Barr virus (EBV), a fatal EBV-associated lymphoproliferative disease (EBV-LPD) of human B cell origin develops in the majority of the hu-PBL-SCID mice. These EBV-LPD tumors have a
Results in adults with small noncleaved cell (SNCL) lymphoma treated with a short duration. Intensive chemotherapy protocol also used in pediatric patients (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A1252 1994. Unique Identifier : AIDSLINE ICDB/94601248; Magrath IT; Adde M; Shad A; Wittes RE; Horak ID; NCI, Bethesda, MD; We have treated 20 adult patients with SNCL (12 BL, 7 non-BL, and 1 indeterminate) with an intensive chemotherapy protocol. None of the patients were infected with HIV. The protocol consisted of two regimens, A and B. Regimen A included CTX, ADR, VCR, and high dose MTX, and regimens B: IFOS, VP16 and high dose Ara-C.
Phase III trial of chemotherapy (CT) concomitantly with didanosine (DDI) versus chemotherapy alone in patients (pts) with AIDS-non Hodgkin's lymphoma (NHL) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A1265 1994. Unique Identifier : AIDSLINE ICDB/94601261; Ucar A; Harrington WJ; Cabral L; Hurley J; Cohen J; Lai S; Byrnes J; Sylvester Comprehensive Cancer Center, Miami, FL; This study was designed to explore the hypothesis that combined antiretroviral and antitumor chemotherapy is feasible and more effective in terms of response and survival. Eligibility criteria included: HIV seropositivity; measurable Stage II-IV intermediate or high grade lymphoma; no prior therapy; Karnofsky PS great
Hypercalcemia in intermediate grade non-Hodgkin's lymphoma (NHL) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A1285 1994. Unique Identifier : AIDSLINE ICDB/94601281; Jendiroba DB; Seymour JF; Swan F; Cabanillas F; UT MD Anderson Cancer Center, Houston, TX 77030; The incidence, features and prognostic significance of hypercalcemia complicating NHL have not been determined. We analyzed 183 consecutive patients (pts) with untreated intermediate-grade NHL treated on protocol between 1988 and 1992. Hypercalcemia was defined as a corrected serum calcium (CCa) of greater than 10 mg/
Cost-benefit analysis of bone marrow (BM) immunophenotyping (IP) in the staging of non-Hodgkin's lymphoma (NHL) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A1332 1994. Unique Identifier : AIDSLINE ICDB/94601328; Denes AE; Hathaway C; St. John's Mercy Medical Center, St. Louis, MO 63141; BM IP is often used in conjunction with light microscopy (LM) in the staging evaluation of patients (pts) with NHL. We conducted a retrospective review of 50 BM staging procedures to determine the sensitivity of IP in the detection of occult BM involvement in pts with NHL. IP was performed on an Epics II Profile flow
Granulocytopenic fever (GCPF) associated with CHOP chemotherapy for intermediate grade non-Hodgkin's lymphoma (IGL); implications for the use of hematopoietic growth factors (HGF) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A1474 1994. Unique Identifier : AIDSLINE ICDB/94601468; Rigden J; Gonin R; Nichols CR; Indiana University School of Medicine, Indianapolis, IN 46202; While Phase II trials suggested a role for dose intensive treatments in IGL, randomized comparisons have suggested that CHOP represents standard treatment (Fisher, NEJM 328(14):1002-6, 1993). Despite two decades of study, clinical aspects of CHOP treatment are not completely defined. In particular, the incidence of GC
Early lymphopenia is a risk factor for chemotherapy induced febrile neutropenia: description of a prognostic index (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A1506 1994. Unique Identifier : AIDSLINE ICDB/94601499; Blay J-Y; Anglaret B; Lasset C; Freyer G; Chauvin F; Biron P; Center L. Berard (CLB), 28 rue Laennec, 69008 Lyon, France; Febrile neutropenia (FN) is a frequent life threatening complication of cytotoxic chemotherapy (CT) whose incidence depends on the doses and drugs and individual factors. Here, we have investigated risk factors (RF) for FN in a retrospective series of 112 cancer patients (pts) treated at the CLB in 1992. Pts were over
Sharing the patient experience in the classroom with the Art for Recovery program (AFR) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A1552 1994. Unique Identifier : AIDSLINE ICDB/94601545; Perlis C; Wallace D; Rosenbaum E; UCSF/Mount Zion Medical Center, 1600 Divisidaro St., San; Francisco CA 94120; Beginning in September of 1992, a co-operative learning/healing project was initiated involving 24 7th and 8th grade students from Brandeis Hillel Day School and 12 adult AFR participants with cancer or AIDS from the medical center. Ms Perlis delivered patients art work and letters to the students each month, facilit
Phase IV clinical evaluation of recombinant human erythropoietin (r-HuEPO) in anemic cancer patients receiving chemotherapy (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A1594 1994. Unique Identifier : AIDSLINE ICDB/94601587; Bukowski R; Glaspy J; Steinberg D; Taylor CW; Vadhan-Raj S; Sarokhan B; Lonczak L; Cleveland Clinic Foundation, Cleveland, OH; In a series of controlled clinical trials, r-HuEPO increased hematocrit and decreased transfusion requirements after the first month of therapy in anemic cancer patients undergoing chemotherapy. The present open label Phase IV study, conducted mainly in community-based oncology practices, was undertaken to confirm the
Incidence of Kaposi's sarcoma (KS), non-Hodgkin's lymphoma (NHL), and other malignancies in a cohort of gay men with human immunodeficiency virus (HIV) infection (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A2 1994. Unique Identifier : AIDSLINE ICDB/94699998; Lyter D; Bryant J; Thackeray R; Zhao P; Rinaldo C; Kingsley L; Univ. of Pittsburgh, Div. of Medical Oncology, Pittsburgh, PA; Between October 1, 1984 and November 15, 1993, 1199 gay men were followed by the Pitt Men s Study, the Pittsburgh component of the MACS, a study of the natural history of HIV infection. The cohort included 769 HIV seronegative (SN) participants and 430 who were either seropositive (SP) at enrollment or who seroconvert
Pilot study-photodynamic therapy (PDT) for treatment of AIDS-associated Kaposi's sarcoma (AIDS/KS) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A6 1994. Unique Identifier : AIDSLINE ICDB/94600003; Bernstein ZP; Wilson D; Mang TS; Dept. of Medicine and Radiation Medicine, Roswell Park Cancer; Inst.; Lesions of AIDS/KS are often painful and cosmetically disfiguring. Treatment options are often limited by the patient s poor immune status. In an attempt to offer palliative therapy which would not further compromise the patient s immune system, we initiated a pilot study of PDT in AIDS/KS. The therapy is predicated o
Clinical trial and post-marketing safety profile of Filgrastim in oncology patients (Neupogen) (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A543 1994. Unique Identifier : AIDSLINE ICDB/94600539; McLeish S; Decoster G; Rich W; Amgen Inc., Thousand Oaks, CA 91320-1789; Filgrastim (Neupogen) is widely used in oncology patients to decrease the incidence of infection as manifested by febrile neutropenia. We have reviewed the safety profile for Filgrastim from pre-marketing studies in oncology patients. This included data from 638 patients who participated in 14 clinical studies. These
Value of lymph node biopsy in the treatment of patients with the human immunodeficiency virus.: Am J Surg. 1991 Dec;162(6):590-2; discussion 592-3. Unique Identifier : AIDSLINE MED/94270435; Wong R; Rappaport W; Gorman S; Darragh M; Hunter G; Witzke D; University of Arizona, Department of Surgery, Tucson 85724.; The indications and value of lymph node biopsy in patients infected with the human immunodeficiency virus (HIV) are not clearly defined. We reviewed 29 consecutive lymph node biopsies performed on 24 patients with the HIV over a 4-year period. Indications for biopsy included: (1) new or worsening medical symptoms with
Drug misuse.: Occas Pap R Coll Gen Pract. 1992 Dec;(58):44-9. Unique Identifier : AIDSLINE MED/94258139; Waller T; 1. Assessment by history and examination should include: a history of all drugs taken during each day for the previous 7 days (including alcohol), length of drug use and route (including the sharing of needles or syringes), the possibility of pregnancy if female, previous psychiatric history and treatment of drug misu
Is the Centers for Disease Control's latest move a cop-out or political posturing? [editorial]: AORN J. 1992 Sep;56(3):419-20. Unique Identifier : AIDSLINE MED/94280166; Palmer PN
Position on HIV and nursing students defined [news]: AORN J. 1992 Sep;56(3):506. Unique Identifier : AIDSLINE MED/94280177
[Health benefits of contraception]: Duodecim. 1992;108(23-24):2083-7. Unique Identifier : AIDSLINE MED/94283191; Luukkainen T; Helsingin yliopiston laaketieteellisen kemian laitos, Helsinki,; Finland.
[Beyond system (interview by Siv Barstad)]: J Sykepleien. 1993 Oct 5;81(16):20-1. Unique Identifier : AIDSLINE MED/94250495; Meyer M
[Operated on for panic (interview by Siv Barstad)]: J Sykepleien. 1993 Oct 5;81(16):30-1. Unique Identifier : AIDSLINE MED/94250500; Blomhoff S
[Valiant effort against AIDS (news)]: J Sykepleien. 1993 Oct 5;81(16):35. Unique Identifier : AIDSLINE MED/94250503
Global programme on AIDS. A study on the effect of blood transfusion on survival among children in a Kenyan hospital.: Wkly Epidemiol Rec. 1994 Mar 11;69(10):69-71. Unique Identifier : AIDSLINE MED/94250523
Tuberculosis in the Caribbean 1983-1992.: Wkly Epidemiol Rec. 1994 Mar 11;69(10):73-4. Unique Identifier : AIDSLINE MED/94250525
[Euthanasia--even a hopeless prognosis does not justify controlled killing]: Kinderkrankenschwester. 1994 Mar;13(3):114. Unique Identifier : AIDSLINE MED/94250540; Schell W
HIV infection and the gynaecologist [editorial]: Br J Obstet Gynaecol. 1994 Mar;101(3):187-9. Unique Identifier : AIDSLINE MED/94250610; Shah PN; Smith JR; Kitchen VS; Barton SE
Working towards a European strategy for intervention to reduce vertical transmission of HIV.: Br J Obstet Gynaecol. 1994 Mar;101(3):192-6. Unique Identifier : AIDSLINE MED/94250612; Newell ML; Peckham CS; Department of Paediatric Epidemiology, Institute of Child Health,; London.
[Usefulness of the detection of antigens and antibodies for the diagnosis of the infection by the human immunodeficiency virus (editorial)]: An Med Interna. 1994 Feb;11(2):53-5. Unique Identifier : AIDSLINE MED/94250765; Rodriguez Iglesias MA; Gutierrez Fernandez J
Pharmacokinetics of zidovudine and acetaminophen in a patient on chronic acetaminophen therapy.: Ann Pharmacother. 1994 Mar;28(3):327-30. Unique Identifier : AIDSLINE MED/94250987; Burger DM; Meenhorst PL; Koks CH; Beijnen JH; Department of Pharmacy, Slotervaart Hospital, Amsterdam, The; Netherlands.; OBJECTIVE: To report a case of a potential interaction between acetaminophen and zidovudine in a patient who had used high daily doses of acetaminophen over many years. CASE SUMMARY: A 43-year-old man presented with HIV-1 infection, recurrent oral candidiasis, and chronic use of acetaminophen, codeine, and diazepam be
Otic administration of amphotericin B 0.25% in sterile water.: Ann Pharmacother. 1994 Mar;28(3):333-5. Unique Identifier : AIDSLINE MED/94250989; Kintzel PE; Trausch DE; Copfer AL; Inpatient Pharmacy, University Medical Center, University of; Arizona Health Sciences Center, Tucson 85724.; OBJECTIVE: To report otic administration of parenteral amphotericin B 0.25% in sterile water. CASE SUMMARY: A 44-year-old HIV+ man was diagnosed with otitis externa. The patient s past medical history was remarkable for positive Coccidioides immitis serology for more than five months, essential hypertension, and Barre
Ten years after acquiring an HIV-1 infection: a study in a cohort of eleven neonates infected by aliquots from a single plasma donation.: Acta Paediatr. 1994 Feb;83(2):173-8. Unique Identifier : AIDSLINE MED/94251071; van den Berg H; Gerritsen EJ; van Tol MJ; Dooren LJ; Vossen JM; Department of Paediatrics, Leiden University Hospital, The; Netherlands.; We present data from a 10-year follow-up study of 11 children who had been infected in the neonatal period by small aliquots of plasma from a single donation. Three of the children died within the first 2.5 years of life, 5 other children died between 6.2 and 11 years after infection and 3 are alive at present. The la
Unilocular toxoplasmosis simulating intracerebral tumor.: Bildgebung. 1994 Mar;61(1):44-6. Unique Identifier : AIDSLINE MED/94251092; Fellner F; Schmitt R; Helmberger T; Busing CM; Obletter N; Institut fur Strahlendiagnostik, Klinikum Ingolstadt.; Toxoplasmosis is a common infection with increased incidence in patients suffering from AIDS. In this paper we report a rare case of toxoplasmosis without evidence of AIDS: The patient had a singular tumor-like lesion in the right parietal lobe in CT and MRI. In neurosurgical intervention no tumor was found. Finally,
Trichosanthin, a ribosome inactivating and anti-HIV protein, does not alter the concentration of beta-endorphin in the mouse brain.: Biochem Mol Biol Int. 1993 Dec;31(6):1101-4. Unique Identifier : AIDSLINE MED/94251174; Ng TB; Kwong WH; Yeung HW; Department of Biochemistry, Faculty of Medicine, Chinese; University of Hong Kong.; Trichosanthin was administered intramuscularly into mature male ICR mice at a dosage of 0.2mg/25g, daily for three days. The mice were sacrificed four hours after the last injection. Their brains were dissected out and divided into three regions: A(thalamus and hypothalamus), B(cerebral cortex) and C(cerebellum and br
Isoniazid prophylaxis of tuberculosis.: Monaldi Arch Chest Dis. 1994 Feb;49(1):88. Unique Identifier : AIDSLINE MED/94251223; Nardini S; Divisione di Pneumologia, Ospedale Civile, USL, Venezia-Mestre,; Italy.
Markedly reduced mortality associated with corticosteroid therapy of Pneumocystis carinii pneumonia in children with acquired immunodeficiency syndrome [see comments]: Arch Pediatr Adolesc Med. 1994 Jun;148(6):638-41. Unique Identifier : AIDSLINE MED/94251314; Bye MR; Cairns-Bazarian AM; Ewig JM; Division of Pediatric Pulmonary Medicine, Columbia Presbyterian; Medical Center, New York, NY.; BACKGROUND: Pneumocystis carinii pneumonia is a common opportunistic infection in pediatric acquired immunodeficiency syndrome (AIDS). Mortality rates of 34% have been reported for the acute infection, with much higher mortality rates occurring in the presence of respiratory failure. Corticosteroids reduce the morbidi
The nurse and the HIV patient--what should the healthcare policy be?: Revolution. 1993 Winter;3(4):12-6, 81. Unique Identifier : AIDSLINE MED/94251446; Monteith SK
The healing relationship.: Revolution. 1993 Winter;3(4):18-9. Unique Identifier : AIDSLINE MED/94251447; Aylor R
Recent advances in the development and use of plasma concentrates.: Br J Hosp Med. 1994 Feb 2-15;51(3):119-22. Unique Identifier : AIDSLINE MED/94251506; Soutar RL; Aberdeen Royal Infirmary.; The consequences of blood donations infected with human immunodeficiency virus, the rapid advances in protein fractionation and the introduction of recombinant DNA technology have revolutionized the range of plasma products available to the clinician. This article reviews these developments and describes recent recomm
[Drug addiction and AIDS]: Bull Acad Natl Med. 1993 Nov;177(8):1353-69. Unique Identifier : AIDSLINE MED/94251630; Gentilini M; Duneton P
[Inter- and intra-cephalic variations in pathogenicity in Toxoplasma gondii. Clinical and epidemiologic consequences]: Bull Acad Natl Med. 1993 Nov;177(8):1411-9; discussion 1419-21. Unique Identifier : AIDSLINE MED/94251636; Ambroise-Thomas P; Okay T; Departement de Parasitologie-Mycologie Medicale et; Moleculaire, Faculte de Medecine, Universite Joseph Fourier,; Grenoble.; Clinical and epidemiological studies, especially the ones conducted in HIV+ patients indicate that the pathogenicity of Toxoplasma gondii varies according to the strain considered. The differences observed among strains are represented by distinct genomic DNA patterns which could be experimentally evaluated by means o
Significance of soluble interleukin-2 receptor levels for evaluation of the progression of adult T-cell leukemia.: Cancer. 1994 Jun 1;73(11):2753-8. Unique Identifier : AIDSLINE MED/94251714; Kamihira S; Atogami S; Sohda H; Momita S; Yamada Y; Tomonaga M; Blood Transfusion Service, Nagasaki University Hospital, Japan.; BACKGROUND. The authors conducted a survey of a large cohort of patients with adult T-cell leukemia (ATL) and a group of human T-cell leukemia virus type 1 (HTLV-1) carriers to elucidate whether measurements of soluble interleukin-2 receptor (sIL-2R) levels are indicative of ATL tumor burden and correlate with clinica
Ultraviolet irradiation and cytokines as regulators of HIV latency and expression.: Chem Biol Interact. 1994 Jun;91(2-3):101-9. Unique Identifier : AIDSLINE MED/94251836; Vicenzi E; Poli G; AIDS Immunopathogenesis Unit, San Raffaele Hospital, Centro San; Luigi, Milan, Italy.; The ability of the human immunodeficiency virus (HIV) to persist and replicate in human CD4+ T lymphocytes and mononuclear phagocytes is under the control of both virally encoded proteins and a variety of host-related factors. Ultraviolet (UV) light has been shown to induce transcription and expression of HIV. Both DN
Effect of human immunodeficiency virus type 1 (HIV-1) monocyte-derived macrophages infection on the manganous superoxide dismutase gene expression.: Chem Biol Interact. 1994 Jun;91(2-3):123-31. Unique Identifier : AIDSLINE MED/94251838; Raoul H; Mabondzo A; Le Naour R; Dormont D; Laboratoire de Neuropathologie experimentale et Neurovirologie,; CRSSA/DSV/DPTE, Commissariat a l'Energie Atomique, Fontenay aux; Roses, France.; Clinical and biological features indicate that a dysregulation of microbicidal activity occurs in the cells of mononuclear phagocytic lineage of HIV-1-infected patients. Thus, the regulation of MnSOD gene expression has been investigated during the 10 h following in vitro HIV macrophage infection. As previously report
Oxygen radical release by neutrophils of HIV-infected patients.: Chem Biol Interact. 1994 Jun;91(2-3):141-6. Unique Identifier : AIDSLINE MED/94251840; Jarstrand C; Akerlund B; Department for Clinical Microbiology, Huddinge University; Hospital, Sweden.; Neutrophils from asymptomatic HIV-infected patients have an increased Nitroblue tetrazolium (NBT) reduction, that is an increased production of oxygen radicals. Plasma from these patients can activate normal neutrophils to an increased NBT-reduction and the neutrophil activating factor thus seems to be mainly plasma b
Imbalance between oxidants and antioxidants in the lungs of HIV-seropositive individuals.: Chem Biol Interact. 1994 Jun;91(2-3):147-58. Unique Identifier : AIDSLINE MED/94251841; Buhl R; Pulmonary Department/ZIM, Frankfurt University Hospital, Germany.; Following the initial infection with HIV, there is evidence of immune dysfunction despite an apparent normal clinical state. In the context that the lung is a major site affected by opportunistic infection, and that some components of the immune system are activated during early HIV infection, we hypothesized that the
Increased production of reactive oxygen species in pharmacologically-immunosuppressed patients.: Chem Biol Interact. 1994 Jun;91(2-3):159-64. Unique Identifier : AIDSLINE MED/94251842; de Lorgeril M; Richard MJ; Arnaud J; Boissonnat P; Guidollet J; Dureau G; Renaud S; Favier A; Institut National pour la Sante et la Recherche Medicale U.63,; Bron, France.; HIV-infected patients and transplanted patients share similar immunosuppressed status. Recent insights gained through the field of heart transplantation may help to clarify the role of reactive oxygen species in HIV-infected patients.
Antioxidant status and lipid peroxidation in patients infected with HIV.: Chem Biol Interact. 1994 Jun;91(2-3):165-80. Unique Identifier : AIDSLINE MED/94251843; Favier A; Sappey C; Leclerc P; Faure P; Micoud M; GREPO: Groupe de Recherches sur les Pathologies Oxydatives,; Faculte de Pharmacie, Universite de Grenoble, La Tronche,; France.; Deficiency in antioxidant micronutrients have been observed in patients with AIDS. These observations concerning only some isolated nutrients demonstrate a defect in zinc, selenium, and glutathione. An increase in free radical production and lipid peroxidation has been also found in these patients, and takes a great i
Selenium deficiency in HIV infection and the acquired immunodeficiency syndrome (AIDS).: Chem Biol Interact. 1994 Jun;91(2-3):181-6. Unique Identifier : AIDSLINE MED/94251844; Dworkin BM; Section of Nutrition, New York Medical College, Valhalla 10595.; Selenium is required for activity of the enzyme glutathione peroxidase, and selenium deficiency may be associated with myopathy, cardiomyopathy and immune dysfunction including oral candidiasis, impaired phagocytic function and decreased CD4 T-cells. We assessed selenium status in 12 patients with AIDS compared to nor
Could oxidative stress initiate programmed cell death in HIV infection? A role for plant derived metabolites having synergistic antioxidant activity [published erratum appears in Chem Biol Interact 1994 Nov;93(2):173 and 1995 Feb;94(2):165]: Chem Biol Interact. 1994 Jun;91(2-3):187-97. Unique Identifier : AIDSLINE MED/94251845; Greenspan HC; Aruoma OI; Arouma O [corrected to Aruoma OI]; LGD Biomedical Group, Annandale, NJ 08801.; Evidence supports the premise that a pro-oxidant condition exists in HIV-seropositive patients, a result of an overabundance in production of reactive oxygen forms combined with a multilevel deficiency in nutritional and metabolic sources of antioxidants. Apoptosis (a programmed cell death) is recognized as a possible
Effects of glutathione precursors on human immunodeficiency virus replication.: Chem Biol Interact. 1994 Jun;91(2-3):217-24. Unique Identifier : AIDSLINE MED/94251848; Simon G; Moog C; Obert G; Laboratoire common Universite Louis Pasteur/Synthelabo,; Strasbourg, France.; Asymptomatic human immunodeficiency virus (HIV)-seropositive individuals have reduced glutathione (GSH) levels. This has led to the suggestion that elevated intracellular thiols levels may inhibit HIV replication and progression of the disease. We confirmed that N-acetyl-L-cysteine (NAC), a cysteine prodrug which main
HIV-1 reactivation after an oxidative stress mediated by different reactive oxygen species.: Chem Biol Interact. 1994 Jun;91(2-3):79-89. Unique Identifier : AIDSLINE MED/94251850; Piette J; Legrand-Poels S; Laboratory of Fundamental Virology, University of Liege,; Belgium.; An important aspect of infection by the human immunodeficiency virus (HIV-1) type 1 is its long clinical latency period, suggesting that the provirus may remain latent for extended periods of time after primary infection. Numerous factors such as cytokines, tumor promoters, co-infection by several viruses and physical
Attitudes toward childbearing and changes in sexual and contraceptive practices among HIV-infected women.: Cleve Clin J Med. 1994 Mar-Apr;61(2):132-6; quiz 161. Unique Identifier : AIDSLINE MED/94251909; Lai KK; Department of Medicine, University of Massachusetts Medical; Center, Worcester 01655.; BACKGROUND: Women now constitute 12% of persons with acquired immunodeficiency syndrome (AIDS), and three quarters of them are well within their childbearing age. OBJECTIVE: To determine if women infected with human immunodeficiency virus (HIV) change their attitudes toward childbearing and their sexual and contracept
Human bone and tissue allografts. Preparation and safety.: Clin Orthop. 1994 Jun;(303):8-17. Unique Identifier : AIDSLINE MED/94251991; Buck BE; Malinin TI; Department of Orthopaedics and Rehabilitation, University of; Miami School of Medicine, FL 33101.; Currently, modern tissue banks routinely supply requested bone and soft-tissue allografts. These allografts are safe if tissue-bank personnel adhere to the existing methodology for excluding any donors with potential for disease transmission. The authors discard rate after excision of tissues has been approximately 1
Incidence and morbidity of infection by hepatitis C virus in children with acute lymphoblastic leukaemia.: Eur J Pediatr. 1994 Apr;153(4):271-5. Unique Identifier : AIDSLINE MED/94252360; Dibenedetto SP; Ragusa R; Sciacca A; Di Cataldo A; Miraglia V; D'Amico S; Lo Nigro L; Ippolito AM; Division of Paediatric Haematology-Oncology, University of; Catania, Italy.; A group of 90 patients with acute lymphoblastic leukaemia (ALL) in first continuous complete remission (CCR), admitted in our hospital between January 1986 and September 1992, were tested for the presence of antibodies against hepatitis C virus (HCV), antibodies against hepatitis B virus and antibodies against HIV-1 d
Visceral leishmaniasis in a child with HIV-1 infection [letter]: Eur J Pediatr. 1994 Apr;153(4):301-2. Unique Identifier : AIDSLINE MED/94252370; Guarino A; Castaldo A; Di Martino L; Rubino A; Gaeta GB; Gradoni L
Identification of the U-937 membrane-associated proteinase interacting with the V3 loop of HIV-1 gp120 as cathepsin G.: FEBS Lett. 1994 May 23;345(1):81-6. Unique Identifier : AIDSLINE MED/94252410; Avril LE; Di Martino-Ferrer M; Pignede G; Seman M; Gauthier F; Laboratoire d'Enzymologie, Centre National de la Recherche; Scientifique URA 1334, University Francois Rabelais, Faculty of; Medicine, Tours, France.; We have purified a serine proteinase from the membrane of U-937 cells that was inhibited in a tight-binding manner by recombinant gp120 and by peptides mimicking the V3 loop of gp120 [(1993) FEBS Lett. 317, 167-172]. This proteinase has now been characterized, both structurally and functionally. It has a dual trypsin-
Expression of foreign genes in cultured human primary macrophages using recombinant vaccinia virus vectors.: Gene. 1994 May 16;142(2):167-74. Unique Identifier : AIDSLINE MED/94252563; Broder CC; Kennedy PE; Michaels F; Berger EA; Laboratory of Viral Diseases, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.; Recombinant vaccinia viruses (re-VVs) provide an extremely versatile method for the expression of foreign genes in a wide range of cultured cell types of different lineages and species. In the present report, we examine the utility of re-VV vectors for re-protein production in cultured human primary macrophages obtain
[Reformulation regarding dementia. Alzheimer's disease--HIV dementia (news)]: Fortschr Med. 1994 Mar 20;112(8):20-2. Unique Identifier : AIDSLINE MED/94252642; Moosmann EB
[Treatment of patients with acquired (non-HIV) immune deficiencies]: Fortschr Med. 1994 Mar 30;112(9):117-21. Unique Identifier : AIDSLINE MED/94252646; Wilhelm M; Tony HP; Medizinische Poliklinik, Universitat Wurzburg.; Infection continues to remain a major problem in immunodeficient patients. The spectrum of pathogens differs, depending on whether one is dealing with an unspecific immune defect or a specific hormonal or cellular defect. This means that a knowledge of the type of deficiency presenting is of importance for the empiric
[Soon a fully automated HIV test will be ready for marketing (news)]: Fortschr Med. 1994 Mar 30;112(9):13. Unique Identifier : AIDSLINE MED/94252649
HTLV-I messenger RNA is expressed in vivo in adult T-cell leukemia/lymphoma patients: an in situ hybridization study.: Int J Cancer. 1994 Jun 1;57(5):760-4. Unique Identifier : AIDSLINE MED/94252726; Setoyama M; Fujiyoshi T; Mizoguchi S; Katahira Y; Yashiki S; Tara M; Kanzaki T; Sonoda S; Department of Dermatology, Faculty of Medicine, Kagoshima; University, Japan.; Adult T-cell leukemia/lymphoma (ATLL) is a malignancy involving peripheral blood, lymph nodes, skin and other organs. Human T-cell leukemia virus type I (HTLV-I) is etiologically associated with ATLL but cannot be detected by conventional methods in fresh samples of peripheral blood and skin taken from ATLL. The aim o
The knowledge, attitudes and perceived support of Tanzanian nurses when caring for patients with AIDS.: Int J Nurs Stud. 1994 Feb;31(1):77-86. Unique Identifier : AIDSLINE MED/94252792; Kohi TW; Horrocks MJ; Faculty of Nursing, Muhimbili University College of Health; Sciences, Dar es Salaam, Tanzania.; In the literature on AIDS, much attention has been paid to the Western health care workers knowledge of and attitudes toward AIDS. Little is known of the knowledge and attitudes of health care workers of developing countries. This study provides a descriptive and comparative examination of Tanzanian nurses knowledge
Planning home care services for people living with AIDS.: Home Healthc Nurse. 1994 Mar-Apr;12(2):17-23. Unique Identifier : AIDSLINE MED/94252845; Ungvarski PJ; Schmidt J; Neville S; As the number of individuals infected with the human immunodeficiency virus (HIV) increases, so does the demand for healthcare services. The debilitating manifestations seen in the later stages of illness, in association with the diagnosis of acquired immune deficiency syndrome (AIDS), often require the assistance of
Nutrition interventions for the HIV positive client.: Home Healthc Nurse. 1994 Mar-Apr;12(2):35-8. Unique Identifier : AIDSLINE MED/94252848; Merrill A; Several factors contribute to malnutrition during HIV infection. These factors can be grouped into three categories: hypermetabolism, inadequate intake, and malabsorption. This article presents a brief overview of these categories and offers suggestions to help the home healthcare nurse manage nutritional interference
Home care of a malnourished AIDS client.: Home Healthc Nurse. 1994 Mar-Apr;12(2):39-42. Unique Identifier : AIDSLINE MED/94252849; Merrill A; Many HIV positive clients experience malnutrition that may decrease the quality and length of life. The case study in this article includes study questions that provide the home healthcare nurse an opportunity to plan interventions that may increase nutrient intake.
Hospice nursing and the AIDS epidemic.: Home Healthc Nurse. 1994 Mar-Apr;12(2):54-5. Unique Identifier : AIDSLINE MED/94252853; Amenta MO; Shubert V
A rapid and simple screening method for HIV-1 protease inhibitors using recombinant Escherichia coli.: J Antibiot (Tokyo). 1994 Apr;47(4):492-5. Unique Identifier : AIDSLINE MED/94252940; Kaneto R; Kojima I; Shibamoto N; Nishida H; Okamoto R; Akagawa H; Mizuno S; Central Research Laboratories, Mercian Corporation, Fujisawa,; Japan.
Immunomodulation during treatment of polymyositis with plasmapheresis and immunosuppressive drugs.: J Clin Apheresis. 1994;9(1):21-5. Unique Identifier : AIDSLINE MED/94253025; Dau PC; Department of Medicine, Evanston Hospital, IL 60201.; Immunologic studies were carried out in a patient with polymyositis (PM), who showed increasing muscle strength and decreasing serum creatine phosphokinase levels during 20 weeks of treatment with plasmapheresis in conjunction with prednisone and cyclophosphamide. After an initial rise, serum IgG declined with treatme
Tax proteins of human T-cell leukemia virus type 1 and 2 induce expression of the gene encoding erythroid-potentiating activity (tissue inhibitor of metalloproteinases-1, TIMP-1).: J Biol Chem. 1994 May 27;269(21):14946-50. Unique Identifier : AIDSLINE GENBANK/D26513; Uchijima M; Sato H; Fujii M; Seiki M; Department of Molecular Virology and Oncology, Kanazawa; University, Ishikawa, Japan.; A growth factor-like activity for erythroid cells (erythroid-potentiating activity) is produced by the T-cells infected with human T-cell leukemia virus type 2 (HTLV-2) (Gasson, J. C., Golde, D. W., Kaufman, S. E., Westbrook, C. A., Hewick, R. M., Kaufmann, R. J., Wong, G. G., Temple, P. A., Leary, A. C., Brown, E. L.
Molecular cloning and sequencing of a 58-kDa membrane- and microfilament-associated protein from ascites tumor cell microvilli with sequence similarities to retroviral Gag proteins.: J Biol Chem. 1994 May 27;269(21):15067-75. Unique Identifier : AIDSLINE GENBANK/U15425; Juang SH; Huang J; Li Y; Salas PJ; Fregien N; Carraway CA; Carraway KL; Department of Biochemistry and Molecular Biology, University of; Miami School of Medicine, Florida 33101.; The MAT-C1 subline of the 13762 rat mammary adenocarcinoma has highly stable, branched microvilli and immobile cell surface receptors. A membrane- and microfilament-associated 58-kDa protein (p58) in the MAT-C1 microvilli has been implicated in the stabilization of the microvilli and microfilament-membrane interaction
Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein.: J Biol Chem. 1994 Jun 3;269(22):15577-82. Unique Identifier : AIDSLINE MED/94253140; Zhao LJ; Mukherjee S; Narayan O; Department of Microbiology, Molecular Genetics, and Immunology,; University of Kansas Medical Center, Kansas City 66160-7424.; vpr is an accessory gene of human immunodeficiency virus I (HIV-I). Although unnecessary for viral replication in T cell lines, growing evidence suggests that it is essential for virus replication in monocytes/macrophages and for replication in vivo. We expressed HIV-I vpr in Escherichia coli and purified Vpr by affin
Evaluation of a p21e-spiked western blot (immunoblot) in confirming human T-cell lymphotropic virus type I or II infection in volunteer blood donors. The Retrovirus Epidemiology Donor Study Group.: J Clin Microbiol. 1994 Mar;32(3):603-7. Unique Identifier : AIDSLINE MED/94253317; Kleinman SH; Kaplan JE; Khabbaz RF; Calabro MA; Thomson R; Busch M; Southern California Region American Red Cross Blood Services, Los; Angeles 90006.; Current algorithms for the serologic confirmation of human T-cell lymphotropic virus type I and II (HTLV-I/II) antibody reactivity are complicated. We evaluated the performance of an HTLV-I Western blot (immunoblot) spiked with recombinant p21e protein (p21e WB) as an alternative to current confirmatory methods. These
Detection of microsporidia by indirect immunofluorescence antibody test using polyclonal and monoclonal antibodies.: J Clin Microbiol. 1994 Mar;32(3):608-12. Unique Identifier : AIDSLINE MED/94253318; Aldras AM; Orenstein JM; Kotler DP; Shadduck JA; Didier ES; Department of Microbiology, Tulane University Regional Primate; Research Center, Covington, Louisiana 70433.; During a screening for monoclonal antibodies (MAbs) to the microsporidian Encephalitozoon hellem, three murine hybridoma cell lines producing strong enzyme-linked immunosorbent assay (ELISA) reactivities were cloned twice, were designated C12, E9, and E11, and were found to secrete MAbs to the immunoglobulin M isotype
Dilution assay statistics.: J Clin Microbiol. 1994 Mar;32(3):732-9. Unique Identifier : AIDSLINE MED/94253340; Myers LE; McQuay LJ; Hollinger FB; Research Triangle Institute, Research Triangle Park, North; Carolina 27709.; A parametric method of statistical analysis for dilution assays is developed in detail from first principles of probability and statistics. The method is based on a simple product binomial model for the experiment and produces an estimate for the concentration of target entities, a confidence interval for this concent
Comparison of PCR with direct examination of bone marrow aspiration, myeloculture, and serology for diagnosis of visceral Leishmaniasis in immunocompromised patients.: J Clin Microbiol. 1994 Mar;32(3):746-9. Unique Identifier : AIDSLINE MED/94253342; Piarroux R; Gambarelli F; Dumon H; Fontes M; Dunan S; Mary C; Toga B; Quilici M; Laboratoire de Parasitologie-Mycologie, Faculte de Medecine de; la Timone, Marseille, France.; A PCR assay amplifying a repeated sequence from the Leishmania infantum genome was compared with direct examination of bone marrow aspirate, myeloculture, and serology for the diagnosis of visceral leishmaniasis in immunocompromised patients. Of 73 patients living in an area endemic for leishmaniasis and where viscera
Bias of culture techniques for diagnosing mixed Mycobacterium genavense and Mycobacterium avium infection in AIDS.: J Clin Microbiol. 1994 Mar;32(3):828-31. Unique Identifier : AIDSLINE MED/94253357; Kirschner P; Vogel U; Hein R; Bottger EC; Institut fur Medizinische Mikrobiologie, Medizinische Hochschule; Hannover, Germany.; Disseminated Mycobacterium avium infection is a common complication in late-stage AIDS. We describe a patient seropositive for human immunodeficiency virus with a disseminated infection caused by mycobacteria. Acid-fast rods were visible by microscopy in stool and bone marrow and in specimens from skin, liver, spleen,
Utility of paired blood cultures and smears in diagnosis of disseminated Mycobacterium avium complex infections in AIDS patients.: J Clin Microbiol. 1994 Mar;32(3):841-2. Unique Identifier : AIDSLINE MED/94253361; Stone BL; Cohn DL; Kane MS; Hildred MV; Wilson ML; Reves RR; Denver Disease Control Service, Denver Health and Hospital,; Colorado 80204.; For 273 patients evaluated for disseminated Mycobacterium avium complex infection, a total of 1,047 mycobacterial blood cultures (MBCs) were submitted; the M. avium complex was recovered from 140 (13%) of the specimens. Results for the paired MBCs were highly concordant: in 392 of 462 (85%) culture sets, both MBCs wer
Report of the Committee on Infectious Diseases.: J Clin Neurophysiol. 1994 Jan;11(1):128-32. Unique Identifier : AIDSLINE MED/94253377
Periodontal diseases in HIV-infected patients.: J Clin Periodontol. 1994 Apr;21(4):270-80. Unique Identifier : AIDSLINE MED/94253406; Holmstrup P; Westergaard J; Department of Periodontology, School of Dentistry, Faculty of; Health Sciences, University of Copenhagen, Denmark.; Periodontal diseases may be the first clinical sign of human immunodeficiency virus (HIV)-infection. Since the immunosuppression and subsequent susceptibility may alter the responses of the oral tissues as well as the microflora, both periodontal treatment and result of therapy may be modified. The periodontal disease
An evaluation of the treatment effectiveness of the Chicago Health Outreach Acupuncture Clinic.: J Holist Nurs. 1994 Jun;12(2):171-83. Unique Identifier : AIDSLINE MED/94253547; Johnstone H; Marcinak J; Luckett M; Scott J; Acupuncture is a treatment modality that is particularly applicable for homeless clients because of its low cost and portability as well as because of its effectiveness in treating the symptomatology of pain syndromes, substance abuse, and human immunodeficiency virus infection. A two-part descriptive study was conduc
The influence of attitudes on the response to AIDS in the United States.: J Infect Dis. 1994 Jun;169(6):1201-5. Unique Identifier : AIDSLINE MED/94253576; Rogers DE; Department of Medicine, Cornell University Medical College, New; York, New York 10021.
Associations between HLA frequencies and pathogenic features of human immunodeficiency virus type 1 infection in seroconverters from the Amsterdam cohort of homosexual men.: J Infect Dis. 1994 Jun;169(6):1244-9. Unique Identifier : AIDSLINE MED/94253581; Klein MR; Keet IP; D'Amaro J; Bende RJ; Hekman A; Mesman B; Koot M; de Waal LP; Coutinho RA; Miedema F; Department of Clinical Viro-Immunology, Central Laboratory of The; Netherlands, Red Cross Blood Transfusion Service, Amsterdam.; HLA-disease associations may be important for understanding the pathogenesis of human immunodeficiency virus type 1 (HIV-1) infection. Therefore, 106 homosexual men from the Amsterdam Cohort Study on AIDS with a known date of HIV-1 seroconversion were serologically typed for HLA. Several significant associations betwe
Analysis of potential risk factors associated with the development of pancreatitis in phase I patients with AIDS or AIDS-related complex receiving didanosine [see comments]: J Infect Dis. 1994 Jun;169(6):1250-5. Unique Identifier : AIDSLINE MED/94253582; Grasela TH; Walawander CA; Beltangady M; Knupp CA; Martin RR; Dunkle LM; Barbhaiya RH; Pittman KA; Dolin R; Valentine FT; et al; Department of Pharmacy and Social and Preventive Medicine, State; University of New York at Buffalo, School of Pharmacy 14260.; Phase I dose-escalating trials of didanosine revealed dose-limiting toxicities, including pancreatitis, and established a total daily dose of 12.5 mg/kg/day as the maximum tolerated dose. Clinical and pharmacokinetic data of 61 patients from two trials were analyzed to further evaluate the risk of pancreatitis: 1 (6.3
The role of the major histocompatibility complex in human immunodeficiency virus infection--ever more complex? [editorial]: J Infect Dis. 1994 Jun;169(6):1332-3. Unique Identifier : AIDSLINE MED/94253594; Kaslow RA; Mann DL
Alternating nevirapine and zidovudine treatment of human immunodeficiency virus type 1-infected persons does not prolong nevirapine activity.: J Infect Dis. 1994 Jun;169(6):1346-50. Unique Identifier : AIDSLINE MED/94253598; de Jong MD; Loewenthal M; Boucher CA; van der Ende I; Hall D; Schipper P; Imrie A; Weigel HM; Kauffmann RH; Koster R; et al; Department of Virology, Academic Medical Centre, University of; Amsterdam, Netherlands.; The potential use of an alternating treatment strategy with nevirapine and zidovudine in prolonging the antiretroviral effects of nevirapine was evaluated. Ten human immunodeficiency virus type 1 (HIV-1)-infected p24 antigen-positive persons who had n
False-positive rapid plasma reagin tests in human immunodeficiency virus infection and relationship to anti-cardiolipin antibody and serum immunoglobulin levels [see comments]: J Infect Dis. 1994 Jun;169(6):1356-9. Unique Identifier : AIDSLINE MED/94253600; Rusnak JM; Butzin C; McGlasson D; Blatt SP; Department of Infectious Diseases, Wilford Hall Medical Center,; Lackland Air Force Base, Texas 78236-5300.; The incidence of biologic false-positive rapid plasma reagin (RPR) tests may be increased in human immunodeficiency virus (HIV) infection; however, injecting drug use has not been excluded as the cause. Review of 3371 periodic syphilis serology results from 1077 HIV-seropositive patients in the
Glycoforms of alpha 1-acid glycoprotein in sera of human immunodeficiency virus-infected persons.: J Infect Dis. 1994 Jun;169(6):1360-3. Unique Identifier : AIDSLINE MED/94253601; Mackiewicz A; Khan MA; Gorny A; Kapcinska M; Juszczyk J; Calabrese LH; Espinosa LR; Department of Cancer Immunology, Academy of Medicine, GreatPoland; Cancer Center, Poznan.; In acute infections thus far studied, there is a relative increase in plasma protein glycoforms rich in biantennary complex type N-glycans (type I), while in some diseases with chronic inflammatory changes, there is increase in glycoforms with more branched N-glycans (type II). In sera of 109 human immunodeficiency vi
Capacity of human immunodeficiency virus type 1 to infect chimpanzee monocytes in vitro [letter; comment]: J Infect Dis. 1994 Jun;169(6):1407-9. Unique Identifier : AIDSLINE MED/94253613; Mannhalter JW; Husch B; Kupcu Z; Eibl MM
Lymphocyte subset alterations associated with increased spontaneous lymphocyte proliferation in human T lymphotropic virus (HTLV) infection: distinctive patterns for HTLV-I versus HTLV-II infection [letter]: J Infect Dis. 1994 Jun;169(6):1409-10. Unique Identifier : AIDSLINE MED/94253614; Prince HE; Golding J; York J
Role of Fc gamma receptors in cancer and infectious disease.: J Leukoc Biol. 1994 Jun;55(6):816-26. Unique Identifier : AIDSLINE MED/94253701; Wallace PK; Howell AL; Fanger MW; Department of Microbiology, Dartmouth Medical School, Lebanon,; New Hampshire 03756.; Receptors for the Fc domain of immunoglobulin G (Fc gamma R) provide an interface between specific humoral immunity and the cellular branch of the immune system through their interaction with antibody. Cross-linking Fc gamma R on myeloid cells triggers such diverse functions as clearance of immune complexes, phagocyto
Coordinate defects in human histocompatibility leukocyte antigen class II expression and antigen presentation in bare lymphocyte syndrome.: J Exp Med. 1994 Jun 1;179(6):2017-22. Unique Identifier : AIDSLINE MED/94253742; Kovats S; Drover S; Marshall WH; Freed D; Whiteley PE; Nepom GT; Blum JS; Immunology and Diabetes Programs, Virginia Mason Research Center,; Seattle, Washington 98101.; The human immunodeficiency, type II bare lymphocyte syndrome (BLS), has been attributed to a defect in the transcription of class II histocompatibility genes. Immunocompetence, as assessed by functional exogenous antigen presentation, was not restored in immortalized B cells, derived from a BLS patient, after transfec
Florida's tuberculosis epidemic. Public health response.: J Fla Med Assoc. 1994 Mar;81(3):178-82. Unique Identifier : AIDSLINE MED/94253795; Witte JJ; Bigler WJ; State Health Office, Department of Health and Rehabilitative; Services, Tallahassee.; Florida ranked fourth in the nation with 1,707 tuberculosis cases reported in 1992 for a rate of 12.7 per 100,000 population. Thirteen percent of these patients had AIDS. Recent cases in prisons, shelters, hospitals and schools have stimulated interest and media coverage. Resurgence of strains of multiple-drug resista
Cerebrovascular and neurological disorders associated with antiphospholipid antibodies in CSF and serum.: J Neurol Sci. 1994 Mar;122(1):97-101. Unique Identifier : AIDSLINE MED/94253843; Gallo P; Sivieri S; Ferrarini AM; Giometto B; Ruffatti A; Ritter E; Chizzolini C; Tavolato B; Institute of Neurology, University of Padua, School of Medicine,; Italy.; Paired serum and cerebrospinal fluid (CSF) samples from 70 patients with inflammatory and non-inflammatory neurological diseases, as well as 10 sera from patients with primary antiphospholipid syndrome (PAS), six of which presented with cerebrovascular ischemic syndromes, were studied for the presence of anticardiolip
Immunoscintigraphy of Pneumocystis carinii pneumonia in AIDS patients [see comments]: J Nucl Med. 1994 Jun;35(6):1028-34. Unique Identifier : AIDSLINE MED/94253898; Goldenberg DM; Sharkey RM; Udem S; Vagg R; Levine GM; Conte P; Swayne LC; Hansen HJ; Cunniff D; Anton J; et al; Garden State Cancer Center at Center for Molecular Medicine and; Immunology, Newark, New Jersey 07103.; The diagnosis of Pneumocystis carinii pneumonia (PCP) currently relies upon cytological demonstration of the organism in sputum or bronchoscopy specimens. The purpose of this study was to develop a radiolabeled monoclonal antibody (Mab) against Pneumocystis carinii (P. carinii) and to evaluate its use for imaging PCP.
PCP, AIDS and nuclear medicine [editorial; comment]: J Nucl Med. 1994 Jun;35(6):1034-7. Unique Identifier : AIDSLINE MED/94253899; Kramer EL
Pneumocystis carinii pneumonia presenting as focal bibasilar uptake on gallium scan during aerosolized pentamidine prophylaxis [see comments]: J Nucl Med. 1994 Jun;35(6):1038-40. Unique Identifier : AIDSLINE MED/94253900; Katial R; Honeycutt W; Oswald SG; Department of Medicine, Dwight D. Eisenhower Army Medical Center,; Fort Gordon, Georgia.; Radionuclide imaging with gallium is commonly performed in the evaluation of patients with suspected Pneumocystis carinii pneumonia (PCP) and is known to be highly sensitive for detection of PCP. We present a patient with acquired immunodeficiency who developed PCP in the bases of both lungs while on aerosolized penta
Hyperperfusion and early technetium-99m-HMPAO SPECT appearance of central nervous system toxoplasmosis.: J Nucl Med. 1994 Jun;35(6):1041-3. Unique Identifier : AIDSLINE MED/94253901; Catafau AM; Sola M; Lomena FJ; Guelar A; Miro JM; Setoain J; Department of Nuclear Medicine, Hospital Clinic i Provincial,; University of Barcelona, Spain.; Three correlative 99mTc-HMPAO brain SPECT studies were performed on an AIDS patient from the early stage of a CNS toxoplasma lesion to its resolution after specific therapy. A hyperactive area in the right parieto-occipital lobe appeared in the first SPECT study, matching the heterogeneous T2-weighted image with Gd-DT
Occupationally acquired tuberculosis: what's known.: J Occup Med. 1994 Mar;36(3):320-5. Unique Identifier : AIDSLINE MED/94253937; Bowden KM; McDiarmid MA; National Naval Medical Center, Bethesda, Maryland.; Tuberculosis (TB) morbidity and mortality have increased substantially since the mid-1980s in areas with a high prevalence of medically underserved populations, human immunodeficiency virus, foreign-born persons, residents of long-term care facilities and crowded correctional institutions, and alcoholics and intraveno
Empyema thoracis in AIDS [editorial]: J R Soc Med. 1994 Feb;87(2):65-7. Unique Identifier : AIDSLINE MED/94254071; Coker RJ
Alternative native flap conformation revealed by 2.3 A resolution structure of SIV proteinase.: J Mol Biol. 1994 May 27;239(1):97-103. Unique Identifier : AIDSLINE MED/94254094; Wilderspin AF; Sugrue RJ; Department of Crystallography, Birkbeck College, London, England.; A large conformational change is observed between HIV-1 proteinase in the ligand-free state and in complexes with transition-state inhibitors. Crystal structures of this enzyme have either the flaps open for the native or ligand-free enzyme or the flaps closed for peptidomimetic ligand-bound enzyme. We describe the st
Syringe and needle exchange to prevent HIV infection [letter; comment]: JAMA. 1994 Jun 15;271(23):1825-6; discussion 1826-7. Unique Identifier : AIDSLINE MED/94254187; Heimer R; Lopes M
[Pathogenesis of Graves' disease]: Nippon Rinsho. 1994 Apr;52(4):1110-7. Unique Identifier : AIDSLINE MED/94254232; Yokoyama N; Nagataki S; First Department of Internal Medicine, Nagasaki University School; of Medicine.; The discovery of long acting thyroid stimulator in Graves disease and autoantibodies specific for the thyroid in Hashimoto disease in 1956, were the earliest examples of autoimmune responses. Autoimmune thyroid disease has many important advantages in the investigation of autoimmune disease when compared to the other
[Research from practice--for your work]: Krankenpfl Soins Infirm. 1994 Mar;87(3):14-8, 55-8. Unique Identifier : AIDSLINE MED/94254418; Brechbuhler M
The use of a scanning proton microprobe to observe anti-HIV drugs within cells.: Life Sci. 1994;54(21):1607-12. Unique Identifier : AIDSLINE MED/94254632; Cholewa M; Legge GJ; Weigold H; Holan G; Birch CJ; Micro Analytical Research Centre (MARC), School of Physics,; University of Melbourne, Parkville, Vic., Australia.; A series of inorganic polyanions (viz. heteropolytungstates) has been shown to have antiviral activity but there was no evidence to indicate that the drugs reached their site of antiviral (HIV) activity intact. We have shown that with a scanning proton microprobe it is possible to analyse the metal content of individu
[Ecology of Cryptococcus neoformans in central Africa]: Med Trop (Mars). 1994;54(1):53-5. Unique Identifier : AIDSLINE MED/94254704; Swinne D; Taelman H; Batungwanayo J; Bigirankana A; Bogaerts J; Laboratoire de Mycologie, Institut de Medecine Tropicale; d'Anvers, Belgique.; Cryptococcosis associated with AIDS is mainly due to Cryptococcus neoformans var. neoformans which is found in saprophytic form in pigeon droppings. This variety has been isolated in Central Africa, particularly in Zaire , Burundi and
[Tuberculosis at the time of AIDS in sub-Saharan Africa. Experience in a central African country: Burundi]: Med Trop (Mars). 1994;54(1):67-74. Unique Identifier : AIDSLINE MED/94254708; Aubry P; Kamanfu G; Mlika-Cabanne N; Nikoyagize E; Fagard C; Niyongabo T; Larouze B; Service de Medecine, Centre Hospitalier Universitaire de; Kamenge, Faculte de Medecine de Bujumbura, Burundi.
Mucosal origin of AIDS.: Med Hypotheses. 1994 Jan;42(1):43-4. Unique Identifier : AIDSLINE MED/94254744; Bourinbaiar AS; Department of Pediatrics, NYU Medical Center, NY 10016.; The natural history of AIDS implies sexual and breast-milk transmission of HIV across the mucosal lining of digestive and reproductive organs. Intraepithelial mucosal lymphocytes specialized in handling foods, air-borne, and microbial pathogens crossing the mucosal barrier represent up to 90% of immunocompetent cells
[Primary and secondary prevention of Pneumocystis carinii pneumonia with pentamidine aerosol. Effectiveness, side effects and incidence of extrapulmonary Pneumocystis carinii manifestations]: Med Klin. 1994 Mar 15;89(3):132-5. Unique Identifier : AIDSLINE MED/94254759; Stoehr A; Plettenberg A; Albrecht H; Stellbrink HJ; Meigel W; Begemann F; Allgemeines Krankenhaus St. Georg, Interdisziplinare; HIV-Ambulanz Hamburg.; BACKGROUND: We report on a retrospective study in 544 HIV-positive patients, (42 women, 502 men, mean age 35 years) showing CD4 lymphocyte counts below 200 c/mcl or after their cure of Pneumocystis carinii pneumonia, who received 300 mg pentamidine aerosol as prophylaxis against Pneumocystis carinii pneumonia every fo
Presence of negative and positive cis-acting RNA splicing elements within and flanking the first tat coding exon of human immunodeficiency virus type 1.: Mol Cell Biol. 1994 Jun;14(6):3960-70. Unique Identifier : AIDSLINE MED/94254853; Amendt BA; Hesslein D; Chang LJ; Stoltzfus CM; Department of Microbiology, University of Iowa, Iowa City 52242.; The human immunodeficiency virus type 1 (HIV-1) RNA follows a complex splicing pathway in which a single primary transcript either remains unspliced or is alternatively spliced to more than 30 different singly and multiply spliced mRNAs. We have used an in vitro splicing assay to identify cis elements within the viral
Constitutive NF-kappa B activity in neurons.: Mol Cell Biol. 1994 Jun;14(6):3981-92. Unique Identifier : AIDSLINE MED/94254855; Kaltschmidt C; Kaltschmidt B; Neumann H; Wekerle H; Baeuerle PA; Institute of Biochemistry, Albert-Ludwigs-Universitat, Freiburg,; Germany.; NF-kappa B is inducible transcription factor present in many cell types in a latent cytoplasmic form. So far, only immune cells including mature B cells, thymocytes, and adherent macrophages have been reported to contain constitutively active forms of NF-kappa B in the nucleus. A recent study showed that the human imm
Jacalin, a lectin with anti-HIV-1 properties, and HIV-1 gp120 envelope protein interact with distinct regions of the CD4 molecule.: Mol Immunol. 1994 Jun;31(8):569-75. Unique Identifier : AIDSLINE MED/94254890; Corbeau P; Haran M; Binz H; Devaux C; CRBM-UPR 9008 du CNRS, Institut de Biologie-Faculte de; Medecine, Montpellier, France.; Jacalin is a multimeric plant lectin able to interact with the lymphocyte cell-surface molecule CD4, a known receptor for the human immunodeficiency virus type 1 (HIV-1). Moreover, jacalin is able to block HIV-1 infection of CD4+ lymphoblastoid cells. Here we studied whether jacalin prevents HIV-1 gp120-CD4 interactio
Movement disorders with cerebral toxoplasmosis and AIDS [letter; comment]: Mov Disord. 1994 Mar;9(2):244-5. Unique Identifier : AIDSLINE MED/94254924; Linazasoro G
[Medical secrecy does not count in AIDS patients (news)]: Ned Tijdschr Geneeskd. 1994 Apr 30;138(18):929. Unique Identifier : AIDSLINE MED/94255034; Meijer van Putten JB
[Bell's palsy in HIV infection]: Minerva Med. 1994 Mar;85(3):117-9. Unique Identifier : AIDSLINE MED/94255098; Mastroianni A; Coronado O; Manfredi R; Chiodo F; Istituto Malattie Infettive, Universita degli Studi di Bologna.; Neurological complications represent one of the most important causes of morbidity and mortality in patients with HIV infection or AIDS. The peripheral nervous system is frequently involved in different stages of HIV disease, and the etiopathogenetic mechanisms are various. Idiopathic peripheral facial nerve palsy (Be
Intravitreal use of foscarnet: retinotoxicity of repeated injections in the rabbit eye.: Ophthalmic Res. 1994;26(2):110-5. Unique Identifier : AIDSLINE MED/94255196; Turrini B; Tognon MS; De Caro G; Secchi AG; Institute of Ophthalmology, University of Padua, School of; Medicine, Italy.; Cytomegalovirus retinitis is the most frequent ocular opportunistic infection in AIDS patients. In selected cases intravitreal injections of foscarnet may be the sole therapeutic possibility. The retinal toxicity of the drug, however, has not yet been thoroughly investigated. Our present study in the rabbit eye concer
Identification of the primary site of the human immunodeficiency virus type 1 RNA dimerization in vitro.: Proc Natl Acad Sci U S A. 1994 May 24;91(11):4945-9. Unique Identifier : AIDSLINE MED/94255445; Skripkin E; Paillart JC; Marquet R; Ehresmann B; Ehresmann C; Unite Propre de Recherche 9002 du Centre National de la; Recherche Scientifique, Institut de Biologie Moleculaire et; Cellulaire, Strasbourg, France.; The diploid genome of all retroviruses is made of two homologous copies of RNA intimately associated near their 5 end, in a region called the dimer linkage structure. Dimerization of genomic RNA is thought to be important for crucial functions of the retroviral life cycle (reverse transcription, translation, encapsid
Potent inhibition of human immunodeficiency virus type 1 replication by an intracellular anti-Rev single-chain antibody.: Proc Natl Acad Sci U S A. 1994 May 24;91(11):5075-9. Unique Identifier : AIDSLINE MED/94255473; Duan L; Bagasra O; Laughlin MA; Oakes JW; Pomerantz RJ; Dorrance H. Hamilton Laboratories, Department of Medicine,; Jefferson Medical College, Thomas Jefferson University,; Philadelphia, PA 19107.; Human immunodeficiency virus type 1 (HIV-1) has a complex life cycle, which has made it a difficult target for conventional therapeutic modalities. A single-chain antibody moiety, directed against the HIV-1 regulatory protein Rev, which rescues unspliced viral RNA from the nucleus of infected cells, has now been devel
Neurovirulent strains of Alphavirus induce apoptosis in bcl-2-expressing cells: role of a single amino acid change in the E2 glycoprotein.: Proc Natl Acad Sci U S A. 1994 May 24;91(11):5202-6. Unique Identifier : AIDSLINE MED/94255499; Ubol S; Tucker PC; Griffin DE; Hardwick JM; Department of Neurology, Johns Hopkins University School of; Medicine, Baltimore, MD 21287.; The isolation and sequence comparison of avirulent and neurovirulent strains of polio virus, alpha virus, herpes virus, immunodeficiency virus, and other viruses have identified genetic changes that are required to cause disease in the nervous system. The molecular mechanisms by which these genetic changes result in n
[Antimalarial 10 H-indolo(3,2-b)quinolin-11-yl-amines. 1. Phenol-Mannich-bases of the amodiaquine and cycloquine type.: Pharmazie. 1994 Apr;49(4):231-5. Unique Identifier : AIDSLINE MED/94255521; Gorlitzer K; Stockmann R; Walter RD; Institut fur Pharmazeutische Chemie, Technischen Universitat; Braunschweig.; The 11-chloro-quinoline derivatives 3 react with 4-aminophenol and the mono- and bis-phenol-Mannich-bases 6 to yield the 10H-indolo[3,2-b]quinoline-11-yl-amines 4 and 7. The amodiaquine analogue 7a as the best of all compounds shows a comparable activity with choroquine and inhibits a multiresistant Plasmodium falcipa
[Schizophrenia as a metaphor (editorial)]: Psychiatr Prax. 1994 Mar;21(2):47-9. Unique Identifier : AIDSLINE MED/94255557; Finzen A
Association of demographic characteristics, knowledge, and worry about HIV infection with occupational and nonoccupational behaviors of medical students.: Psychol Rep. 1994 Apr;74(2):587-93. Unique Identifier : AIDSLINE MED/94255598; Toennies LM; Zagumny MJ; Sorokin G; Tesch B; Medical College of Wisconsin.; The authors surveyed a sample of 132 medical students to assess their behaviors related to the risk of HIV infection. Scale measures were computed for survey questions relating to both occupational and nonoccupational behavior and also for questions relating to knowledge of any worry about HIV infection. Regression an
Clinically significant cognitive dysfunction in medically asymptomatic human immunodeficiency virus-infected (HIV+) individuals? [editorial; comment]: Psychosom Med. 1994 Jan-Feb;56(1):18-9. Unique Identifier : AIDSLINE MED/94255613; Martin A
Neuropsychological impairment in human immunodeficiency virus-infection: implications for employment. HNRC Group. HIV Neurobehavioral Research Center [see comments]: Psychosom Med. 1994 Jan-Feb;56(1):8-17. Unique Identifier : AIDSLINE MED/94255622; Heaton RK; Velin RA; McCutchan JA; Gulevich SJ; Atkinson JH; Wallace MR; Godfrey HP; Kirson DA; Grant I; University of California, San Diego, School of Medicine.; Individuals infected with the human immunodeficiency virus-Type 1 (HIV-1), are at increased risk for neurobehavioral impairment, particularly in later stages of the disease. Even patients in the medically asymptomatic or minimally symptomatic stages of infection may show mild deficits on comprehensive neuropsychologic
[Knowledge about HIV infection in a group of professional nursing students]: Riv Inferm. 1994 Jan-Mar;13(1):16-21. Unique Identifier : AIDSLINE MED/94255667; Villa A; De Gobbis M; Capuzzi M; Esposito A; Zanotto G; Confalonieri F; A confidential questionnaire was given to 241 students of the nursing school of a Milano Hospital to record the knowledge on HIV infection and their experience with HIV patients during their training in wards different from Infectious Departments. The results evidence a good level of knowledge, comparable to the itali
Zidovudine reduces HIV transmission from mother to infant [news]: RN. 1994 May;57(5):81. Unique Identifier : AIDSLINE MED/94255696
[HIV and blood donors: past, present and future]: Sangre (Barc). 1994 Feb;39(1):15-21. Unique Identifier : AIDSLINE MED/94255827; Leon de Gonzalez G; Hernandez T; Arias F; Celis S; Acosta V; Semprun O; Lugo de Moron M; Banco Municipal de Sangre del D.F. Servicio de; Inmunohematologia, San Jose Caracas, Venezuela.; PURPOSE: To evaluate the changes in the spectrum of HIV-positive blood donors along seven years. PATIENTS AND METHODS: The municipal Blood Bank of Caracas Federal District examined 193,796 blood donors between 1986 and 1992. Anti-HIV antibodies were determined by the following methods: Ortho HIV-Elisa Test System (59.
[Bone marrow granulomas]: Sangre (Barc). 1994 Feb;39(1):35-8. Unique Identifier : AIDSLINE MED/94255831; Vijnovich Baron IA; Barazzutti L; Tartas N; Korin J; Sanchez Avalos JC; Departamento de Patologiay Citologia, Sanatorio Guemes, Buenos; Aires, Argentina.; PURPOSE: To evaluate bone marrow granulomatous lesions in order to establish their etiology. MATERIAL AND METHODS: 2,250 bone marrow biopsies were studied during the period of March 1983-March 1991. Granulomas and/or granulomatous lesions were found in 24 of them (1.06%). A correlation between histological characteris
Infections in the immunocompromised patient.: Surg Clin North Am. 1994 Jun;74(3):609-20. Unique Identifier : AIDSLINE MED/94255849; Howard RJ; Department of Surgery, University of Florida College of Medicine,; Gainesville.; Specific microorganisms have certain types of host defenses directed at them. Inhibition of different host defenses, therefore, leads to an increased risk of the host for infection with different organisms. This article discusses the types of infections present in immunocompromised patients as well as a general approa
[Therapy of HIV infection with nucleoside analogs]: Z Gastroenterol. 1993 Nov;31 Suppl 5:60-6. Unique Identifier : AIDSLINE MED/94256156; Jablonowski H; Mauss S; Armbrecht C; Manegold C; Szelenyi H; Hengels KJ; Abteilung fur Gastroenterologie, Medizinische Klinik und; Poliklinik, Heinrich-Heine-Universitat, Dusseldorf.
[Brazil: street children in the risk zone for HIV and AIDS]: Vardfacket. 1993 Aug 26;17(13):24-5. Unique Identifier : AIDSLINE MED/94256173; Ommundsen C
Alcohol and drug use and sexual behaviors placing runaways at risk for HIV infection.: Addict Behav. 1994 Jan-Feb;19(1):95-103. Unique Identifier : AIDSLINE MED/94256250; Koopman C; Rosario M; Rotheram-Borus MJ; Department of Psychiatry & Behavioral Sciences, Stanford; University School of Medicine, CA 94305-5544.; Lifetime and current alcohol and drug use and sexual risk acts were examined among 154 male and 148 female runaways, aged 11-19, predominantly Black and Hispanic, residing at four residential shelters in the New York City area. Most runaways reported alcohol (71%) and drug use (46%), with about a quarter (27%) using e
Idiopathic, herpetic, and HIV-associated facial nerve palsies: abnormal MR enhancement patterns.: AJNR Am J Neuroradiol. 1994 Mar;15(3):479-85. Unique Identifier : AIDSLINE MED/94256300; Sartoretti-Schefer S; Wichmann W; Valavanis A; Department of Neuroradiology, University Hospital of Zurich,; Switzerland.; PURPOSE: To determine specific criteria that can be used to define normal versus abnormal MR contrast enhancement of the facial nerve. METHODS: Twenty-three patients with acute unilateral inflammatory peripheral facial nerve palsy were examined on a 1.5-T MR using multiplanar T1-weighted spin-echo sequences before and
Intestinal permeability in patients infected with the human immunodeficiency virus.: Am J Gastroenterol. 1994 Jun;89(6):878-82. Unique Identifier : AIDSLINE MED/94256460; Tepper RE; Simon D; Brandt LJ; Nutovits R; Lee MJ; Division of Gastroenterology, Bronx Municipal Hospital Center,; New York.; OBJECTIVE: The etiology of acquired immunodeficiency syndrome (AIDS) enteropathy is unknown. This condition has been associated with malabsorption and villous atrophy. Other disorders with similar findings, including celiac disease, are characterized by altered intestinal permeability. Our objective was to confirm (or
Combined daily therapy with intravenous ganciclovir and foscarnet for patients with recurrent cytomegalovirus retinitis.: Am J Ophthalmol. 1994 Jun 15;117(6):776-82. Unique Identifier : AIDSLINE MED/94256533; Weinberg DV; Murphy R; Naughton K; Department of Ophthalmology, Northwestern University Medical; School, Chicago, Illinois.; We treated seven patients (nine eyes) who had cytomegalovirus retinitis with daily intravenous ganciclovir plus foscarnet. All patients had demonstrated multiple progressions of retinitis on single-drug therapy, and some were intolerant to induction doses of one or both medications
Risk factors for development of rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis [letter; comment]: Am J Ophthalmol. 1994 Jun 15;117(6):820-1. Unique Identifier : AIDSLINE MED/94256550; Geier SA; Klauss V; Goebel FD
Flow cytometric analysis of lymphocyte subsets of mice maintained on an ethanol-containing liquid diet.: Alcohol Clin Exp Res. 1994 Feb;18(1):12-20. Unique Identifier : AIDSLINE MED/94256579; Hsiung L; Wang J; Waltenbaugh C; Department of Microbiology-Immunology, Northwestern University; Medical School, Chicago, IL 60611.; Alcoholic patients often have impaired immune function, yet little is known about the precise mechanism(s) of this impairment. We have previously shown that ethanol consumption by mice alters copolymer-specific humoral and cellular immune responses. In this study, we asked whether alcohol consumption by mice would phe
Effect of postnatal ethanol exposure on expression of differentiation antigens of murine splenic lymphocytes.: Alcohol Clin Exp Res. 1994 Feb;18(1):21-8. Unique Identifier : AIDSLINE MED/94256594; Giberson PK; Blakley BR; Department of Veterinary Physiological Sciences, Western College; of Veterinary Medicine, University of Saskatchewan, Saskatoon,; Canada.; Ethanol is a recognized immunosuppressive agent in the chronic alcoholic. However, the effects of ethanol exposure on the developing immune system have not been extensively investigated. This study evaluated the effects of early postnatal ethanol exposure, via breast milk, on splenic lymphocyte differentiation antigen
Modification of lymphocyte subsets in the intestinal-associated immune system and thymus by chronic ethanol consumption.: Alcohol Clin Exp Res. 1994 Feb;18(1):8-11. Unique Identifier : AIDSLINE MED/94256603; Lopez MC; Huang DS; Borgs P; Wang Y; Watson RR; Department of Family and Community Medicine, Arizona Health; Sciences Center, Tucson 85724.; Modification of the mucosa-associated intestinal immune system of female C57BL/6 mice was studied during consumption of the Lieber-DeCarli diet supplemented with 5% v/v ethanol or laboratory chow with ethanol (20% w/v) in the drinking water. All groups received ethanol for 11 weeks. Mice fed the Lieber-DeCarli diet ha
Allergen-induced expression of cell surface markers on lymphocytes of Chi t I-sensitized patients.: Allergy. 1994 Mar;49(3):163-9. Unique Identifier : AIDSLINE MED/94256625; Liebers V; Raulf M; Baur X; Berufsgenossenschaftliches Forschungsinstitut fur Arbeitsmedizin; (BGFA), Ruhr-Universitat Bochum, Germany.; Lymphocyte cultures of persons sensitized to the hemoglobin allergen Chi t I show a highly significant response to the allergen measured in the lymphocyte stimulation assay by (3H)-thymidine uptake. In this study, we investigated by flow cytometry the expression of different cell surface markers on lymphocytes after i
The HIV-positive physician and disability insurance.: Ann Emerg Med. 1994 Jun;23(6):1355-62. Unique Identifier : AIDSLINE MED/94256695; Lavely R; Department of Public Health, Yale School of Medicine, New Haven,; Connecticut.; Occupational exposure to HIV is becoming a daily hazard in many emergency departments. Emergency physicians who are protected by disability insurance policies are likely to believe that if they are unable to continue working because of HIV-positive status, their disability policies will provide them with a source of i
Induction of apoptosis in a T lymphoblastoid cell line infected with feline immunodeficiency virus.: Arch Virol. 1994;135(1-2):153-8. Unique Identifier : AIDSLINE MED/94256834; Ohno K; Okamoto Y; Miyazawa T; Mikami T; Watari T; Goitsuka R; Tsujimoto H; Hasegawa A; Department of Veterinary Internal Medicine, Faculty of; Agriculture, University of Tokyo, Japan.; The mechanism of cell death induced by feline immunodeficiency virus (FIV) infection was investigated in an interleukin 2( IL-2 )-dependent T-lymphoblastoid cell line (MYA-1). DNA extracted from FIV-infected MYA-1 cells showed a ladder of nucleosomal DNA, indicating that
Expression of env gene of bovine leukemia virus in rodent cells.: Arch Virol. 1994;135(1-2):201-7. Unique Identifier : AIDSLINE MED/94256841; Zajac V; Slavikova K; Babusikova O; Department of Experimental Pathology, Slovak Academy of Sciences,; Bratislava.; The BamHI-BamHI fragment of the env gene of bovine leukemia virus (BLV) cloned in pMMEx expression vector was transfected into Chinese hamster cells. Monoclonal antibodies (MAbs) directed against both conformational and sequential epitopes of gp51 of BLV recognized viral polypeptides expressed in hamster cells in West
Salmonella typhimurium activates human immunodeficiency virus type 1 in chronically infected promonocytic cells by inducing tumor necrosis factor-alpha production.: Biochem Biophys Res Commun. 1994 May 30;201(1):16-23. Unique Identifier : AIDSLINE MED/94256973; Andreana A; Gollapudi S; Kim CH; Gupta S; Division of Basic and Clinical Immunology, University of; California, Irvine 92717.; The effect of phagocytosis of Salmonella typhimurium on human immunodeficiency virus type 1 (HIV-1) production was investigated using a chronically infected promonocytic cell line (U1) that contains HIV-1 provirus but produces little or no HIV-1. The phagocytosis of virulent S. typhimurium by U1 cells resulted in an i
Competitive inhibition of HIV-1 protease by warfarin derivatives.: Biochem Biophys Res Commun. 1994 May 30;201(1):290-4. Unique Identifier : AIDSLINE MED/94256992; Tummino PJ; Ferguson D; Hupe D; Department of Biochemistry, Parke-Davis Pharmaceutical Research,; Division of Warner-Lambert Company, Ann Arbor, Michigan 48105.; The oral anticoagulant warfarin (4-hydroxy-3-(3-oxo-1-phenylbutyl)- benzopyran-2-one) is a structurally novel low micromolar competitive inhibitor of HIV-1 protease in vitro. It was recently reported that warfarin inhibits HIV-1 infection in U-1 monocytes and viral production in ACH-2 lymphocytes (Bourinbaiar, A.S. et
Macrogolgin--a new 376 kD Golgi complex outer membrane protein as target of antibodies in patients with rheumatic diseases and HIV infections.: J Autoimmun. 1994 Feb;7(1):67-91. Unique Identifier : AIDSLINE GENBANK/X75304; Seelig HP; Schranz P; Schroter H; Wiemann C; Renz M; Institute of Immunology and Molecular Genetics, Karlsruhe,; Germany.; Antibodies against the Golgi complex (GC) were found by indirect immunofluorescence microscopy in the serum of two patients with sclerodermia and Sjogren syndrome. Serum from one patient was used to screen clones from an oligo (dT) primed HeLa cDNA expression library. Four overlapping cross hybridizing clones (G1, G12
History of the Euro Skin Bank: the innovation of preservation technologies.: Burns. 1994;20 Suppl 1:S43-7. Unique Identifier : AIDSLINE MED/94257162; Hoekstra MJ; Kreis RW; du Pont JS; Euro Skin Bank, Research Department, Beverwijk, The Netherlands.; A skin bank facility is indispensable for burn care. In Holland, a skin bank was established in October 1976 on a national basis for economical reasons. Since 1981, overcoming early rejection by innovation of existing, and development of new, preservation technologies became the main scientific objective. The immunolo
Virucidal effect of glycerol as used in donor skin preservation [see comments]: Burns. 1994;20 Suppl 1:S77-80. Unique Identifier : AIDSLINE MED/94257169; van Baare J; Buitenwerf J; Hoekstra MJ; du Pont JS; Euro Skin Bank, Research Department, Beverwijk, The Netherlands.; Glycerol has been used for a long time as a viral preservation medium in tissue samples at a 50 per cent concentration, however after a limited time span viruses could no longer be detected. This fact combined with the dehydrating action of glycerol, raised the suspicion that glycerol in a higher concentration could b
Cohort study of HIV infection among drug users in Ruili, Longchuan and Luxi of Yunnan Province, China.: Biomed Environ Sci. 1993 Dec;6(4):348-51. Unique Identifier : AIDSLINE MED/94257171; Zheng XW; Zhang JP; Tian CQ; Cheng HH; Yang XZ; Duan S; Li DQ; Institute of Epidemiology and Microbiology, Chinese Academy of; Preventive Medicine, Beijing.; In March 1992, KAP investigation and HIV blood test were carried out for 860 drug users and 82 spouses in Ruili, Luxi, Longchuan of Yunnan Province, China . The results showed that there were 285 injecting drug users (IDUs) (33.1%) among 860 drug users. Among 282 blood samples of IDU
Molecular biology of HIV: challenges for the second decade.: AIDS Res Hum Retroviruses. 1994 Feb;10(2):111-2. Unique Identifier : AIDSLINE MED/94257313; Poeschla E; Wong-Staal F; Department of Medicine, University of California, San Diego, La; Jolla 92093-0665.
Human immunodeficiency virus type 1 infection of neonatal severe combined immunodeficient mice xenografted with human cord blood cells.: AIDS Res Hum Retroviruses. 1994 Feb;10(2):131-41. Unique Identifier : AIDSLINE MED/94257317; Reinhardt B; Torbett BE; Gulizia RJ; Reinhardt PP; Spector SA; Mosier DE; Department of Pediatrics, University of California, San Diego, La; Jolla 92037-0672.; In these studies, neonatal C.B-17 severe combined immunodeficient (nSCID) mice were reconstituted with human cord blood leukocytes (hu-CBLs). The resulting hu-CBL-nSCID mice contained readily detectable human CD3+ T lymphocytes and CD20+ human B cells, and produced substantial levels of human IgM and IgG (including al
Identification of novel neutralization-inducing regions of the human T cell lymphotropic virus type I envelope glycoproteins with human HTLV-I-seropositive sera.: AIDS Res Hum Retroviruses. 1994 Feb;10(2):163-73. Unique Identifier : AIDSLINE MED/94257321; Desgranges C; Souche S; Vernant JC; Smadja D; Vahlne A; Horal P; INSERM U271, Lyon, France.; The humoral immune response in sera from 30 human T cell lymphotropic virus type I (HTLV-I)-positive individuals from Martinique in the French West Indies was studied. The subjects were subdivided into those suffering from TSP/HAM a
Human herpesvirus 6 envelope glycoproteins B and H-L complex are undetectable on the plasma membrane of infected lymphocytes.: AIDS Res Hum Retroviruses. 1994 Feb;10(2):175-9. Unique Identifier : AIDSLINE MED/94257322; Cirone M; Campadelli-Fiume G; Foa-Tomasi L; Torrisi MR; Faggioni A; Department of Experimental Medicine, University of Rome La; Sapienza, Italy.; Membrane immunofluorescence analysis of cells infected with either variant (A or B) of human herpesvirus 6 revealed a typical punctate staining, after labeling with several HHV-6-positive human sera or with two monoclonal antibodies directed to gB and gH. Immunoprecipitation studies showed a sharp difference in glycop
In vitro susceptibility of Macaca nemestrina to human herpesvirus 6: a potential animal model of coinfection with primate immunodeficiency viruses.: AIDS Res Hum Retroviruses. 1994 Feb;10(2):181-7. Unique Identifier : AIDSLINE MED/94257323; Lusso P; Secchiero P; Crowley RW; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.; Human herpesvirus 6 (HHV-6), a lymphotropic herpesvirus, has been suggested as a potential cofactor in the acquired immunodeficiency syndrome (AIDS). Previous studies indicate that HHV-6 has a restricted range of susceptible species. In this study, we tested the in vitro susceptibility to HHV-6 of Macaca nemestrina (p
Passive immunization of cynomolgus macaques with immune sera or a pool of neutralizing monoclonal antibodies failed to protect against challenge with SIVmac251.: AIDS Res Hum Retroviruses. 1994 Feb;10(2):189-94. Unique Identifier : AIDSLINE MED/94257324; Kent KA; Kitchin P; Mills KH; Page M; Taffs F; Corcoran T; Silvera P; Flanagan B; Powell C; Rose J; et al; National Institute for Biological Standards and Control, South; Mimms, Potters Bar, Herts, England.; In the first of two passive transfer experiments, three groups of four macaques were injected intraperitoneally with a normal serum pool, an immune serum pool (pool 1) collected 132-172 weeks postinfection with the 11/88 pool of SIVmac251, or with a pool of four neutralizing monoclonal antibodies (KK9, 17, 54, and 56)
Reduced virus load in rhesus macaques immunized with recombinant gp160 and challenged with simian immunodeficiency virus.: AIDS Res Hum Retroviruses. 1994 Feb;10(2):195-204. Unique Identifier : AIDSLINE MED/94257325; Ahmad S; Lohman B; Marthas M; Giavedoni L; el-Amad Z; Haigwood NL; Scandella CJ; Gardner MB; Luciw PA; Yilma T; Department of Pathology, Microbiology, and Immunology, University; of California at Davis 95616.; As a safe alternative to inactivated and live-attenuated whole-virus SIV vaccines, we have evaluated the potential of SIVmac239 gp160 expressed by recombinant vaccinia virus (vSIVgp160) and baculovirus (bSIVgp160) to protectively immunize rhesus macaques against intravenous (i.v.) infection with pathogenic SIVmac isol
Production of long-lived neutralizing antibodies to HIV-1 IIIB in mice with a vaccinia recombinant virus-infected cell vaccine expressing gp160.: AIDS Res Hum Retroviruses. 1994 Feb;10(2):205-12. Unique Identifier : AIDSLINE MED/94257326; Parry C; McLain L; Dimmock NJ; Department of Biological Sciences, University of Warwick,; Coventry, England.; A formaldehyde-fixed cell vaccine in adjuvant (syngeneic cells infected with a vaccinia virus recombinant expressing gp160: vacc-gp160) stimulated only nonneutralizing antibody when used on its own in four strains of mice, but a similar nonfixed cell vaccine stimulated neutralizing antibodies up to a titer of 1/320 in
Titration and characterization of two rhesus-derived SIVmac challenge stocks.: AIDS Res Hum Retroviruses. 1994 Feb;10(2):213-20. Unique Identifier : AIDSLINE MED/94257327; Lewis MG; Bellah S; McKinnon K; Yalley-Ogunro J; Zack PM; Elkins WR; Desrosiers RC; Eddy GA; Henry M. Jackson Foundation, Rockville, Maryland 20850.; Simian immunodeficiency virus infection of macaques is a model for human immunodeficiency virus infection of humans. In vivo-titrated stocks of SIV are essential for the utilization of this model for vaccine development. The elicitation of anti-human cell antibodies by some vaccines prepared in human cells and the rel
Feasibility of developing live attenuated HIV vaccines: conclusions and recommendations. World Health Organization Working Group.: AIDS Res Hum Retroviruses. 1994 Feb;10(2):221-2. Unique Identifier : AIDSLINE MED/94257328
Guidelines on HIV testing [news]: Nurs Stand. 1994 Apr 13-19;8(29):8. Unique Identifier : AIDSLINE MED/94257468
Adult T-cell leukaemia/lymphoma featuring a large granular lymphocyte leukaemia morphologically.: Br J Haematol. 1994 Feb;86(2):383-5. Unique Identifier : AIDSLINE MED/94257503; Sakamoto Y; Kawachi Y; Uchida T; Abe T; Mori M; Setsu K; Indo N; Department of Internal Medicine, Takamatsu Red Cross Hospital,; Kagawa, Japan.; A 70-year-old man from an endemic area of human T-cell lymphotropic virus type I (HTLV-I) developed rapid generalized lymphadenopathy and abdominal tumours. The white blood cell count was 198.3 x 10(9)/l with 93% lymphocytes, 66.3% of which expressed large granular lymphocytes (LGLs). Bone marrow and lymph nodes were
XrelA, a Xenopus maternal and zygotic homologue of the p65 subunit of NF-kappa B. Characterisation of transcriptional properties in the developing embryo and identification of a negative interference mutant.: Mech Dev. 1994 Feb;45(2):173-89. Unique Identifier : AIDSLINE MED/94257534; Richardson JC; Garcia Estrabot AM; Woodland HR; Department of Biological Sciences, University of Warwick,; Coventry, UK.; We have isolated two clones (XrelA.1 and XrelA.2) from Xenopus ovary representing differentially processed mRNAs homologous throughout their translated regions to the mammalian p65 subunit of NF-kappa B. The transcripts are ubiquitously present throughout development, but are most abundant in late blastulae and gastru
Aggressive orbital lymphoma in AIDS.: Br J Ophthalmol. 1994 Apr;78(4):319-21. Unique Identifier : AIDSLINE MED/94257606; Rahhal FM; Rosberger DF; Heinemann MH; Department of Ophthalmology, New York Hospital-Cornell University; Medical College, New York.
Oligonucleotide-poly(L-lysine)-heparin complexes: potent sequence-specific inhibitors of HIV-1 infection.: Bioconjug Chem. 1994 Jan-Feb;5(1):8-13. Unique Identifier : AIDSLINE MED/94257725; Degols G; Devaux C; Lebleu B; Institut de Genetique Moleculaire Montpellier,; CNRS-Universite de Montpellier, France.; Poly(L-lysine)-conjugated oligonucleotides complementary to the translation initiation region of the tat protein were tested for their capacity to inhibit HIV-1 replication in de novo infected cells. Sequence-specific antiviral effects were observed with these conjugates at 0.5 microM; their activity was transient, an
Acquired heart disease in children.: Curr Opin Cardiol. 1994 Jan;9(1):121-9. Unique Identifier : AIDSLINE MED/94257868; Bezold LI; Bricker JT; Baylor College of Medicine, Texas Children's Hospital, Houston.; Recent advances have been made in understanding Kawasaki disease, acute rheumatic fever and rheumatic heart disease, cardiomyopathy, and acquired immunodeficiency syndrome. Immune-mediated tissue injury in Kawasaki disease is likely caused by response to a superantigen. Persistent functional and anatomic coronary abno
Inadequate dietary intake and altered nutrition status in early HIV-1 infection.: Nutrition. 1994 Jan-Feb;10(1):16-20. Unique Identifier : AIDSLINE MED/94257925; Baum M; Cassetti L; Bonvehi P; Shor-Posner G; Lu Y; Sauberlich H; Department of Epidemiology and Public Health, University of Miami; School of Medicine, Florida 33101.; Recent studies indicate that multiple nutritional abnormalities occur relatively early in the course of human immunodeficiency virus (HIV-1) infection. Decreased plasma levels of vitamins B6, B12, A, and E and zinc have been correlated with dietary intake and associated with significant alterations in immune response
[HIV and travel. Advice concerning immunizations and pre-travel evaluation]: Can Fam Physician. 1994 Apr;40:740-5. Unique Identifier : AIDSLINE MED/94258038; Tessier D; Gervais F; Clinique sante-voyage de l'Hopital Saint-Luc.; HIV and AIDS infection has reached epidemic proportions; however, advances in treatment have made it possible for an increasing number of infected individuals to travel. These patients should be given travel advice before they leave. Mainly for political reasons, they should be advised to avoid certain countries. For
BC's AIDS road show. Evolution of a good idea [news]: Can Fam Physician. 1994 Apr;40:842-3. Unique Identifier : AIDSLINE MED/94258042; McNeil L
[Predictors of sexual behavior in a group of heterosexual university students at risk for AIDS in Montreal]: Contracept Fertil Sex. 1994 Feb;22(2):123-8. Unique Identifier : AIDSLINE MED/94258234; Levy JJ; Frigault LR; Samson JM; Dupras A; Cappon P; Departement de sexologie, Universite du Quebec a Montreal,; Canada.; In order to evaluate the predictors of risky sexual behavior and AIDS, 573 male and female college students enrolled in French speaking universities in Montreal answered a questionnaire dealing with their sexual behaviors, from which an index of risks was computed (CASH). The analyses show that the best predictors of
Risk of infection from blood and blood products in the context of the AIDS scandal in Germany.: Int J Clin Pharmacol Ther. 1994 Jan;32(1):2-6. Unique Identifier : AIDSLINE MED/94258370; Kretschmer V; Abteilung fur Transfusionsmedizin und Gerinnungsphysiologie,; Universitats-Klinikums in Marburg, Germany.
The association of physical and sexual abuse with HIV risk behaviors in adolescence and young adulthood: implications for public health.: Child Abuse Negl. 1994 Mar;18(3):233-45. Unique Identifier : AIDSLINE MED/94258556; Cunningham RM; Stiffman AR; Dore P; Earls F; George Warren Brown School of Social Work, Washington University,; St. Louis, MO 63130.; This paper explores the relationship between changes in HIV risk behaviors and physical and sexual abuse. A stratified random sampling procedure selected 602 youths from a sample of 2,787 patients seen consecutively at public health clinics in 10 cities. Face-to-face structured interviews conducted since 1984-85 provi
Keep facts from patients at your peril, Ontario court warns doctors.: Can Med Assoc J. 1994 Jun 1;150(11):1863-5. Unique Identifier : AIDSLINE MED/94258619; Capen K
Epstein-Barr virus in patients with polymorphic reticulosis (lethal midline granuloma) from China and Japan.: Cancer. 1994 Jun 15;73(12):3041-6. Unique Identifier : AIDSLINE MED/94258673; Mishima K; Horiuchi K; Kojya S; Takahashi H; Ohsawa M; Aozasa K; Department of Pathology, Nara Medical College, Kashihara, Japan.; BACKGROUND. Polymorphic reticulosis is one of several diseases constituting lethal midline granuloma (LMG). Previous immunohistochemical studies suggested a T-cell nature of proliferating cells; the term nasal T-cell lymphoma (NTL-LMG) has since been used widely. The authors previous study in Asian countries showed t
Posttransplant T-cell lymphoma. Report of three cases and a review of the literature.: Cancer. 1994 Jun 15;73(12):3064-72. Unique Identifier : AIDSLINE MED/94258676; van Gorp J; Doornewaard H; Verdonck LF; Klopping C; Vos PF; van den Tweel JG; Department of Pathology, University Hospital, Utrecht, The; Netherlands.; BACKGROUND. Although 14% of the malignant lymphomas after organ transplantation are reported to be T-cell lymphomas, only a few cases are described in the literature. METHODS. The authors presented three new cases. They summarized the clinical data and analyzed histologic and immunochemical findings. The presence of E
Synthetic peptides of human CD4 enhance binding of immunoglobulins to monocyte/macrophage cells. II. Mechanisms of enhancement.: Cell Immunol. 1994 Jun;156(1):146-54. Unique Identifier : AIDSLINE MED/94258711; Mehta RL; Lenert P; Zanetti M; Department of Medicine, University of California, San Diego, La; Jolla 92093.; We have previously shown that a synthetic peptide corresponding to amino acid residues 21-49 of the first extracellular domain of human CD4 binds immunoglobulins (Ig) and antibody: antigen (Ab:Ag) complexes, and greatly enhances the uptake of aggregated Ig by monocyte/macrophage U937 cells. In this report, we investig
Leukocytes migrate through three-dimensional gels of midcycle cervical mucus.: Cell Immunol. 1994 Jun;156(1):77-94. Unique Identifier : AIDSLINE MED/94258727; Parkhurst MR; Saltzman WM; Department of Chemical Engineering, Johns Hopkins University,; Baltimore, Maryland 21218.; The migration of leukocytes through mucus must be an essential factor in the mucosal immune response, particularly during mucosal invasion by pathogens. We used two methods to evaluate the ability of neutrophils to migrate through human midcycle cervical mucus: (i) direct visualization of cell migration within freshly
Induction of graft versus host disease in SCID mice by MRL/lpr cell transfer.: Clin Immunol Immunopathol. 1994 Jun;71(3):265-72. Unique Identifier : AIDSLINE MED/94258819; Fraziano M; Montesano C; Sammarco I; di Cesare S; Caroleo MC; Mattei M; Cannata S; Poccia F; Bellavia A; Salerno A; et al; Department of Biology, University of Rome, Tor Vergata, Italy.; We have investigated the graft versus host (GvH) disease induced in immunodeficient SCID (H-2d) mice by intravenous (iv) or intraperitoneal (ip) transfer of either spleen or lymph node cells from autoimmune (MRL/lpr and MRL/++ mice, H-2k) and normal (CBA, H-2k) mice. Rapid and lethal GvH disease was observed when cell
Structural and functional similarities between synthetic HIV gp41 peptides and defensins.: Clin Immunol Immunopathol. 1994 Jun;71(3):315-24. Unique Identifier : AIDSLINE MED/94258826; Monell CR; Strand M; Department of Pharmacology and Molecular Sciences, Johns Hopkins; University School of Medicine, Baltimore, Maryland 21205.; Synthetic peptides derived from the putative immunosuppressive region of HIV-1 gp41 were examined to identify the amino acids required for suppressive activity. The active sequence was similar to the pseudosubstrate regulatory peptide of protein kinase C and to a sequence from the cyclic immune peptides known as defen
Fulminant amebic colitis. A morphologic study of four cases.: Dis Colon Rectum. 1994 Jun;37(6):535-9. Unique Identifier : AIDSLINE MED/94258928; Chun D; Chandrasoma P; Kiyabu M; Department of Pathology, Los Angeles County-University of; Southern California Medical Center, University of Southern; California School of Medicine, 90033.; PURPOSE: The morphologic features of fulminant amebic colitis are poorly documented. In this report, we describe the clinical and pathologic findings in four of these cases. METHODS: The surgical pathology reports and accompanying histologic slides were examined from four patients who underwent surgical resections for
[Biotechnology vaccines--development of new disease prevention. Research progress of Biocine in Siena--HIV, herpes, Helicobacter]: Fortschr Med. 1994 Apr 20;112(11):53-4. Unique Identifier : AIDSLINE MED/94259369; Keil TU
[AIDS: management still inadequate. Ambulatory care--AIDS counseling]: Fortschr Med. 1994 Apr 30;112(12):32. Unique Identifier : AIDSLINE MED/94259374; Karcher HL
An assessment of Arab American knowledge, attitudes, and beliefs about AIDS.: Image J Nurs Sch. 1994 Spring;26(1):13-7. Unique Identifier : AIDSLINE MED/94259455; Kulwicki A; Cass PS; Oakland University School of Nursing, Rochester, MI 48309-4401.; An important component of an effective AIDS prevention program is the dissemination of relevant information concernin