1994

AIDS 101. [Version 4.0]. [sound recording].: Seattle, Wash. : AIDS Impact, c1993- 3 sound cassettes : analog + 1 guide (103 p.) (HIV/AIDS series) Unique Identifier : AIDSLINE AV/9433031
Tuberculosis update. [videorecording]: Washington, D.C. : Universal Health Associates, c1993 1 videocassette (59 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9430597; Grimes DE; Nursing
AIDS : HIV educational video clips. [videorecording]: Washington, DC : VA, [1993] 1 videocassette (17 min., 9 sec.) : sd., col. ; 1/2 in. + 1 guide (viii, 36 p.) Unique Identifier : AIDSLINE AV/9434018; Shaffer MK; Jensen P; (Producer) This videotape contains a series of seven short scenes of medical center situations to help generate discussion of major concerns surrounding HIV and AIDS. VA clinicians and educators developed the situations.
Jacquelyn Flaskerud, Ph. D., UCLA School of Nursing, studies the cultural impact of AIDS-related education, testing, and counseling for low-income Latina women. [videorecording]: St. Louis, Mo. : Mosby Year-Book, c1993 1 videocassette (32 min.) : sd., col. with b&w ; 1/2 in (Cameo, outstanding nurse researchers and their work ; v. 5) Unique Identifier : AIDSLINE AV/9432506; Flaskerud JH; Cronenwett L; (Producer) Jacquelyn H. Flaskerud is internationally recognized for her cultural research on AIDS education, HIV testing, and counseling for minority women and for her studies examining Asian American clients and mental health services. Dr. Flaskerud is involved in AIDS education and outreach through the UCLA AIDS I
Arizona HIV infection surveillance report.: [Phoenix, Ariz. : The Division, v Unique Identifier : AIDSLINE CAT/9422573
NIAID AIDS agenda.: Bethesda, MD : Office of Communications, National Institute of Allergy and Infectious Diseases (NIAID), v Unique Identifier : AIDSLINE CAT/9432911
HIV-infected health workers : debating the issues.: Denver, Colo. (1560 Broadway, Suite 700, Denver 80202) : National Conference of State Legislatures, 1992 15 p (State legislative report ; vol. 17, no. 18) Unique Identifier : AIDSLINE CAT/9405660; Craig RT; Bryant LL
[Ve stinu AIDS.] Vyd. 1.: Praha : Academia, 1992 164 p. : ill Unique Identifier : AIDSLINE CAT/9410034; Dvorak J
The:AIDS war : propaganda, profiteering, and genocide from the medical-industrial complex.: New York : Asklepios, 1993 479 p. : ill., ports Unique Identifier : AIDSLINE CAT/9421821; Lauritsen J
Health care utilization and charges for AIDS and HIV disease : Massachusetts, 1988-1991.: Boston, MA : Massachusetts Dept. of Public Health, [1993] 29 p. : ill Unique Identifier : AIDSLINE CAT/9434885; Kasabula S
Medical alert : a publication of the National Association of People with AIDS.: Washington, DC : NAPWA, v Unique Identifier : AIDSLINE CAT/9419236
Needle exchange : dimensions of HIV prevention.: Menlo Park, CA : H.J. Kaiser Family Foundation, c1993 xxviii, 182 p. : ill Unique Identifier : AIDSLINE CAT/9421820; Stryker J; Smith MD
5th Annual Conference.: [Melbourne? : The Society, 1993] 112 leaves Unique Identifier : AIDSLINE CAT/9437138
AIDS : 1,000 full-text statistical abstracts from the A Matter of fact database, 1984-1992.: Ann Arbor, Mich. : Pierian Press, 1993 vi, 106 p (Statistical perspectives series ; no. 1) Unique Identifier : AIDSLINE CAT/9423713
AIDS : a modern epidemic.: Washington, D.C. : Pan American Health Organization, Pan American Sanitary Bureau, Regional Office of the World Health Organization, c1993 v, 58 p. : ill (Communicating for health series ; no. 5) Unique Identifier : AIDSLINE CAT/9434043; Chelala CA
A:Death in the family : orphans of the HIV epidemic.: New York, NY : United Hospital Fund of New York, c1993 xv, 157 p. : ill Unique Identifier : AIDSLINE CAT/9431653; Levine C
Management guidelines for the control of infectious disease hazards in health care establishments : report of the Joint NHMRC/ANCA Working Party on Management Guidelines for the Control of Infectious Disease Hazards in Health Care Establishments.: Control of Infectious Disease Hazards in Health Care Establishments Canberra : Australian Govt. Pub. Service, c1993 vi, 64 p Unique Identifier : AIDSLINE CAT/9423796
AIDS care at home : a guide for caregivers, loved ones, and people with AIDS.: New York : J. Wiley & Sons, Inc., c1994 xviii, 360 p. : ill Unique Identifier : AIDSLINE CAT/9434393; Greif J; Golden BA
Measuring patient-reported health status in advanced HIV disease : HIV-PARSE survey instrument.: Santa Monica, CA : Rand, 1994 xi, 61 p. : ill Unique Identifier : AIDSLINE CAT/9437327; Berry SH; Group
Sexual networking and AIDS in sub-Saharan Africa : behavioural research and the social context.: Camberra, ACT, Australia : Health Transition Centre, the Australian National University : Distributed by Bibliotech, ANUTECH, 1994 x, 275 p. : ill (Health transition series ; no. 4) Unique Identifier : AIDSLINE CAT/9433489; Orubuloye IO
Journal of the Physicians Association for AIDS Care. Vol. 1, no. 1 (Jan. 1994)-v. 2, no. 1 (Jan. 1995),: Chicago, IL : PAAC Pub., c1994-c1995 2 v. : ill., ports Unique Identifier : AIDSLINE CAT/9431848
Hives of sickness : public health and epidemics in New York City.: New Brunswick, N.J. : Published for the Museum of the City of New York by Rutgers University Press, c1995 223 p. : ill Unique Identifier : AIDSLINE CAT/9436206; Rosner D
Oncology nursing.: Albany : Delmar Publishers, c1995 xii, 371 p (Plans of care for specialty practice) Unique Identifier : AIDSLINE CAT/9436416; Miaskowski C
Color atlas of ocular manifestations of AIDS : diagnosis and management.: New York : Igaku-Shoin, c1995 xii, 105 p. : ill Unique Identifier : AIDSLINE CAT/9436493; Orellana J; Lieberman RM; Teich SA
HIV/AIDS : a guide to nursing care. 3rd ed.: Philadelphia : Saunders, c1995 xiv, 544 p. : ill Unique Identifier : AIDSLINE CAT/9436868; Flaskerud JH; Ungvarski PJ
Primary care of women and children with HIV infection : a multidisciplinary approach.: Boston : Jones and Bartlett Publishers, c1995 xvi, 308 p. : ill (Jones and Bartlett books on oncology and HIV-related illnesses) Unique Identifier : AIDSLINE CAT/9436871; Kelly P
Forgotten children of the AIDS epidemic.: New Haven : Yale University Press, c1995 xiv, 283 p. : ill Unique Identifier : AIDSLINE CAT/9437464; Geballe S; Gruendel J; Andiman W
Heat shock activation of human T cell leukemia/lymphoma virus type I (HTLV-I) in HTLV-I-transformed cells (MT-2) is associated with down-regulation of cellular heat shock protein (HSP27/28).: Diss Abstr Int [B]; 53(12):6238 1993. Unique Identifier : AIDSLINE ICDB/94696171; Sun D; Univ. of Maryland Baltimore Professional Schools; Temperature elevation constitutes a beneficial component of host defense against viral pathogens. However, virally infected cells may exhibit altered cellular tolerance to thermal stress. Additionally, increased viral oncoprotein expression in virally infected cells during thermal stress may contribute to cellular neo
Results by match-control study from HIV and uterine cervix preneoplasias in population with high and low risk (Meeting abstract).: Gynaecological Oncology, 8th International Meeting of the European Society of Gynaecological Oncology. June 9-12, 1993, Barcelona, Spain, 1993.. Unique Identifier : AIDSLINE ICDB/94698786; Romeo F; No affiliation given; Since the last century, cervical carcinoma became a great medical and social problem. From the beginning studies of Rigoni-Stern to the more recent virologic and immunologic studies, the goal is still the same: find factors that can induct the disease and select risk groups. Actually all the attentions are focused on
Detection of EBV-encoded mRNA in primary central nervous system lymphomas (Meeting abstract).: J Pathol; 170(Suppl):349A 1993. Unique Identifier : AIDSLINE ICDB/94699878; Sanderson P; Angel CA; Royds JA; Clark A; Smith C; Timperley W; Ironside J; Dept. of Pathology, Univ. of Sheffield Medical School, Sheffield,; UK; In recent years, a number of lymphoproliferative diseases have been shown to contain EBV DNA, and evidence to support an etiological relationship between EBV and a variety of lymphomas is accumulating. Primary central nervous system lymphomas are rare, but occur with an increased incidence in immunocompromised individ
Preirradiation chemotherapy (CTX) with cytoxan, Adriamycin, vincristine, and decadron (CHOD) for primary CNS lymphomas (PCNSL): initial report of Radiation Therapy Oncology Group (RTOG) protocol 88-06 (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A485 1994. Unique Identifier : AIDSLINE ICDB/94600481; Schultz C; Scott C; Wasserman T; Fisher B; Abrams R; Sherman W; Fetell M; Nelson J; No affiliation given; From 1988 to 1992, a prospective Phase I/II trial was carried out by the RTOG to test the tolerance and efficacy of preirradiation (RT) CHOD CTX followed by large vol, high-dose brain RT for patients (pts) with PCNSL. Fifty-four (51 evaluable) HIV-negative pts with PCNSL were entered and received 2 (19 pts) or 3 (32 p
BOMES: a promising combination chemotherapy in the treatment of CNS lymphoma (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A500 1994. Unique Identifier : AIDSLINE ICDB/94600496; Cheng AL; Yeh KH; Chen BR; Uen WC; Tien HF; Wang CH; Chen YC; Cancer Res. Center, Natl. Taiwan Univ. Coll. of Medicine, Taipei,; Taiwan; Although with occasionally excellent results with corticosteroid treatment, the response of CNS lymphoma to systemic chemotherapy remains unsatisfactory. This is presumably partly due to the blood-brain barrier (BBB). To cope with this, we designed a protocol which, in addition to
A pilot study of chemotherapy (CTx) of non-Hodgkin's lymphoma arising in the CNS or eye (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A510 1994. Unique Identifier : AIDSLINE ICDB/94600506; Stark-Vancs V; Setser A; Kohler D; Heiss J; Martin D; Nussenblatt R; Whitcup S; deSmet M; Jaffe E; Patronas N; et al; NIH, Bethesda, MD 20892; Eight minimally pretreated patients (pts) with primary CNS lymphoma or CNS metastases from ocular lymphoma (all HIV-) were treated on a pilot study to evaluate the feasibility of a regimen using high-dose methotrexate (MTX) with leucovorin rescue (LCV; Cancer Treat Rev 4:87, 1977),
Interferon-alpha is effective in patients with hairy cell leukemia relapsing after 2-chlorodeoxyadenosine (Meeting abstract).: Proc Annu Meet Am Soc Clin Oncol; 13:A1033 1994. Unique Identifier : AIDSLINE ICDB/94601029; Seymour JF; Estey EH; Keating MJ; Kurzrock R; Department of Clinical Investigation, MD Anderson Cancer Center,; Houston, TX; Interferon-alpha (IFN) produces responses in about 90% of patients (pts) with untreated hairy cell leukemia (HCL). 2-chlorodeoxyadenosine (2-CdA) induces a higher proportion of complete responses (CR) than IFN but also induces prolonged suppression of normal CD4+ and CD8+ lymphocyte counts. The optimal treatment of pt
Conserved sequence homology of cysteine rich regions in genes encoding glycoprotein A in Pneumocystis carinii derived from different host species.: Abstr Gen Meet Am Soc Microbiol. 1994;94:141 (abstract no. D-253). Unique Identifier : AIDSLINE ASM94/94313065; Wright T; Haidaris P; Gigliotti F; Harmsen A; Haidaris C; University of Rochester, NY.; Pneumocystis carinii (Pc) surface glycoprotein A (gpA) exhibits host-species specific phenotypic and genotypic variation. Despite this heterogeneity, the gpAs of Pc isolated from different host species appear to be homologous molecules sharing certain biochemical and antigenic characteristics. Using two degenerate oli
Sequence variations in the internal transcribed spacers of the ribosomal RNA genes of Pneumocystis carinii strains that infect humans.: Abstr Gen Meet Am Soc Microbiol. 1994;94:141 (abstract no. D-255). Unique Identifier : AIDSLINE ASM94/94313066; Lu J; Lee C; Bartlett M; Smith J; Indiana Univ. Sch. of Med., Indianapolis.; Pneumocystis carinii is a major cause of life-threatening pneumonia in immunocompromised patients. It is unknown at present whether the P. carinii infecting humans represents a single type of organism or a group of organisms. To answer this question, we have examined the nucleotide sequences of the internal transcribe
Stabilization and expression of HIVMN genes in Salmonella typhimurium.: Abstr Gen Meet Am Soc Microbiol. 1994;94:151 (abstract no. E-46). Unique Identifier : AIDSLINE ASM94/94313067; Sizemore D; Branstrom A; Sadoff J; Warren R; Walter Reed Army Inst. of Res., Washington, DC.; Stabilization and expression of recombinant plasmids in Salmonella carriers for oral vaccination has proven problematic. Previously, we showed that pSC101 derived plasmids were maintained in Salmonella carriers without selection. However, foreign genes were expressed at low levels. We report the construction of a nove
Parenteral or intranasal immunization with HIV gp160 formulated with proteosomes and/or PA adjuvants enhances epitope-specific IgG or IgA.: Abstr Gen Meet Am Soc Microbiol. 1994;94:155 (abstract no. E-70). Unique Identifier : AIDSLINE ASM94/94313068; Kaminski R; Amselem S; Levi M; Loomis L; Kersey K; Vancott T; Friedman D; Smith G; Wahren B; Redfield R; et al; Walter Reed Army Institute of Research, Washington, DC.; We have immunized mice i.m. or intranasally and rabbits i.m. with HIV gp160 (MicroGeneSys) formulated with alum or proprietary adjuvants (PA, Pharmos) and/or meningococcal outer membrane protein proteosomes. When administered i.m., proteosomes plus alum or PA formulations (with or without proteosomes) induced improved
Floridians' perceptions of AIDS transmission.: Abstr Gen Meet Am Soc Microbiol. 1994;94:156 (abstract no. E-74). Unique Identifier : AIDSLINE ASM94/94313069; Ganguly R; Vincent A; Sinnott JT; Hoecherl S; University of South Florida.; AIDS transmission is heavily influenced by behavior, attitudes and knowledge about the disease among those at risk. This study is based upon the 1991 Florida Behavioral Risk Factor Surveillance System (BRFSS) data which included a module of questions about AIDS transmission and several demographic variables. Through a
Effect of HIV-1 infection on natural killer cells and neutrophils of chimpanzees.: Abstr Gen Meet Am Soc Microbiol. 1994;94:158 (abstract no. E-85). Unique Identifier : AIDSLINE ASM94/94313070; Javadian MA; Lafrado LJ; Couch RC; Marr JM; Boisford JL; Coulston Foundation, WSRC, Alamogordo, NM.; Human infection with HIV-1 is characterized by a variety of profound defects in cellular immunity, including depression in natural killer (NK) cell activity and phagocytic activity of neutrophils which perform important inflammatory and immune functions. In the present experiment, natural killer cell and neutrophil ph
Genetic analysis of Mycobacterium avium superoxide dismutase.: Abstr Gen Meet Am Soc Microbiol. 1994;94:176 (abstract no. U-21). Unique Identifier : AIDSLINE ASM94/94313071; Escuyer V; Haddad N; Berche P; Laboratoire de Microbiologie, INSERM, Faculte de Medecine; Necker-Enfants Malades, Paris, France.; Mycobacterium avium is a major opportunistic pathogen widely spread in the environment and responsible for severe infections in immunocompromised patients with AIDS. It is able to survive and replicate in the phagocytic cells of the host immune system and resists the oxidative burst of activated macrophages. M. avium
Isolation of fastidious mycobacteria from patients with AIDS.: Abstr Gen Meet Am Soc Microbiol. 1994;94:180 (abstract no. U-45). Unique Identifier : AIDSLINE ASM94/94313072; Yajko DM; Clancy MN; Goodman C; Hadley WK; Univ. of California, San Francisco General Hospital.; During a recent 14 month period (6/92-8/93) slow-growing fastidious mycobacteria were recovered at San Francisco General Hospital from 22 specimens submitted from 10 patients with AIDS. Twenty of the isolates (from 9 patients) were recovered from blood and two isolates (from a single patient) were recovered from AFB s
Polymerase chain reaction (PCR) detection of Mycobacterium avium-intracellulare (MAI) DNA from peripheral blood mononuclear cells (PBMCs) of HIV-infected patients.: Abstr Gen Meet Am Soc Microbiol. 1994;94:188 (abstract no. U-91). Unique Identifier : AIDSLINE ASM94/94313073; Kostman J; Mair M; Byrne B; Gekowski K; Baxter J; Cooper Hospital/UMC, Robert Wood Johnson Medical School, Camden,; N.J.; Rapid detection and identification of MAI from the blood of HIV-infected patients is necessary for the prompt initiation of treatment. We performed DNA amplification with the polymerase chain reaction of mycobacterial DNA from frozen PBMCs collected from HIV-infected patients. Heparinized blood was collected from HIV-
Induction of immune mediators by defined lipid fractions from Mycobacterium avium serovar 8.: Abstr Gen Meet Am Soc Microbiol. 1994;94:190 (abstract no. U-102). Unique Identifier : AIDSLINE ASM94/94313074; Barrow W; Davis T; Wright E; Labrousse V; Bachelet M; Rastogi N; Institut Pasteur, Paris, France.; Because of increasing evidence that M. avium lipids can modulate host responses, lipid fractions from M. avium serovar 8 were evaluated for their ability to modulate the immune function of human peripheral blood mononuclear cells. A total lipid fraction was obtained by the Folch extraction procedure and processed by c
Serum markers of immune activation in HIV-associated pulmonary tuberculosis.: Abstr Gen Meet Am Soc Microbiol. 1994;94:190 (abstract no. U-99). Unique Identifier : AIDSLINE ASM94/94313075; Wallis R; Helfand M; Vjecha M; Whalen C; Mugerwa R; Okwera A; Ellner J; Case Western Reserve University, Cleveland, Ohio.; Survival is shortened in HIV-infected patients with tuberculosis (TB) as compared to CD4-matched HIV-infected controls. We measured serum markers of immune activation in HIV-infected patients beginning treatment for pulmonary TB in Kampala, Uganda . Patients were followed for 16 mon
T cell reactivity against antigen 85 in HIV-infection.: Abstr Gen Meet Am Soc Microbiol. 1994;94:190 (abstract no. U-100). Unique Identifier : AIDSLINE ASM94/94313076; Huygen K; Gerard M; Farber CM; Drowart A; van Vooren JP; Clumeck N; Pasteur Instituut van Brabant, Brussels, Belgium.; Antigen 85 (30-32 kD) is the major secreted protein antigen from M. tuberculosis/bovis BCG culture filtrate. We have previously shown that 32 kD component (Ag85A) of this antigen demonstrates powerful T cell stimulatory properties resulting in T cell proliferation and IFN-gamma secretion by PBMC from all healthy tuber
Radiometric susceptibility testing of Mycobacterium tuberculosis against second-line drugs.: Abstr Gen Meet Am Soc Microbiol. 1994;94:197 (abstract no. U-138). Unique Identifier : AIDSLINE ASM94/94313077; Salfinger M; Gross W; Kornblum J; Laszlo A; Pfyffer G; Roberts G; Siddiqi S; NY State Dept. of Health, Albany.; AIDS epidemic, deterioration of the public health infrastructure and inadequate training of health care providers are some factors contributing to the increase of tuberculosis (TB), especially multidrug-resistant TB. In vitro drug susceptibility testing is now required for all TB patients. Since faster turnaround time
Analysis of sewage effluent for human immunodeficiency virus (HIV) using infectivity assay and reverse-transcriptase polymerase chain reaction.: Abstr Gen Meet Am Soc Microbiol. 1994;94:415 (abstract no. Q-154). Unique Identifier : AIDSLINE ASM94/94313078; Palmer CJ; Lee MH; Bonilla GF; Javier BJ; Tsai YL; Sangermano LR; Orange County Sanitation Districts, Fountain Valley, CA.; Environmental survival of human immunodeficiency virus (HIV) is an important public health concern. Survival of HIV in wastewater is of particular interest to those who work at treatment facilities and to the general public who have contact with rivers or ocean water receiving treated sewage effluent. Other researcher
The removal of human immunodeficiency virus (HIV) from fluids containing serum with a 0.04 micron nylon membrane filter.: Abstr Gen Meet Am Soc Microbiol. 1994;94:424 (abstract no. Q-205). Unique Identifier : AIDSLINE ASM94/94313079; Oshima K; Comans T; Rowe T; Orloff S; Highsmith A; Ades E; Centers for Disease Control and Prevention, Atlanta, GA.; The risks associated with blood and blood products contaminated with human immunodeficiency virus (HIV) has been an ongoing concern in the health care industry. We tested the ability of a 0.04 micron nylon membrane filter to remove human immunodeficiency virus (HIV) from fluid containing serum and characterized the ef
Synergistic antiretroviral activities of the herb, Prunella vulgaris, with AZT, ddI, and ddC.: Abstr Gen Meet Am Soc Microbiol. 1994;94:481 (abstract no. S-27). Unique Identifier : AIDSLINE ASM94/94313080; John JF; Kuk R; Rosenthal A; Robert Wood Johnson Medical School, New Brunswick, N.J.; There is a urgent need for new, safe, and inexpensive therapy for HIV infection. We tested a group of commonly available herbs for their activity in aqueous solution against HIV. In screening tests of four commonly used herbs, Prunella vulgaris (PV) was found to exert the best anti-HIV activity. The antiretroviral act
Identification of three distinct HIV-1 subtypes in Brazil based on the protease gene.: Abstr Gen Meet Am Soc Microbiol. 1994;94:482 (abstract no. T-1). Unique Identifier : AIDSLINE ASM94/94313081; Janini LM; Luo CC; Peralta M; Schecther M; Kalish ML; Pieniazek N; de la Torre N; Schochetman G; Rayfield M; Pieniazek D; CDC, Atlanta, GA.; OBJECTIVE: To study genotypic differences in the protease gene from HIV-1 infected persons in Brazil . METHODS: HIV-1 proviral DNA from 40 specimens were surveyed for genetic similarity to reference strains using a PCR typing procedure based on the polymorphism of restriction sites
Identification of HIV-1 variants transmitted from mothers to fetus.: Abstr Gen Meet Am Soc Microbiol. 1994;94:482 (abstract no. T-2). Unique Identifier : AIDSLINE ASM94/94313082; Furtado MR; Hoeft J; Garcia PM; Department of Pathology, Northwestern University, Chicago, IL; 60611.; Identification of HIV-1 sequence variants that are transmitted to infants and determination of the timing of transmission are crucial to understanding the underlying mechanisms. We analyzed fetal tissue from five abortuses and detected HIV-1 DNA in four. Analysis for maternal DNA in the fetal samples by PCR amplificat
p24 Antigen is not primarily virion-associated in peripheral blood of HIV-infected individuals: a comparison with quantitation of HIV RNA.: Abstr Gen Meet Am Soc Microbiol. 1994;94:483 (abstract no. T-8). Unique Identifier : AIDSLINE ASM94/94313083; Wilber J; Yeghiazarian T; Todd J; Urdea M; Chiron Corporation, Emeryville, CA.; The level of p24 antigen has been used as a surrogate marker for the level of viremia in HIV-infected patients. To understand the extent to which p24 antigen (p24Ag) is associated with virions, EDTA plasma was collected from 12 HIV-infected individuals and assayed for the quantity of virion-associated HIV p24Ag and RN
A rapid sensitive, solution based fluorescent in situ hybridization (FISH) assay for the detection of HIV mRNA in infected cell lines by multi-colored flow cytometry.: Abstr Gen Meet Am Soc Microbiol. 1994;94:483 (abstract no. T-3). Unique Identifier : AIDSLINE ASM94/94313084; Poindexter B; Cubbage M; Weber W; Ku J; Bresser J; Aprogenex, Inc., Houston, TX.; Rapid detection of low levels of HIV infected cells is necessary for the screening of donated blood as well as in the clinical diagnosis of infection. Aprogenex has developed an HIV diagnostic test, Virafy, sensitive enough to detect infected cell lines diluted down to 1 in 10,000 with uninfected cell lines by flow cy
Expression of HIV-1 core/envelope chimeric virus-like particles in baculovirus-infected cells.: Abstr Gen Meet Am Soc Microbiol. 1994;94:483 (abstract no. T-7). Unique Identifier : AIDSLINE ASM94/94313085; Truong C; Brand D; Roingeard P; Mallet F; Goudeau A; Barin F; Lab. Virologie, URA CNRS 1334 CHU Bretonneau Tours, France.; The viral envelope, involved in the first steps of HIV-1 infection, contains two neutralizing epitopes. The V3 loop induces an early, type-specific HIV-1 neutralizing activity but is highly variable among isolates. Later in infection, broad spectrum neutralizing activity is induced by the conformational CD4 binding si
Role of Ca(++)-dependent and Ca(++)-independent protein kinase C isozymes on activation of HIV-1.: Abstr Gen Meet Am Soc Microbiol. 1994;94:483 (abstract no. T-6). Unique Identifier : AIDSLINE ASM94/94313086; Kim C; Lim S; Gollapudi S; Gupta S; University of California, Irvine.; Protein kinase C (PKC) plays a crucial role in HIV-1 replication. Because of the recognized molecular and biochemical heterogeneity of PKC, we have studied the effects of various PKC isozyme agonists on HIV-1 activation in chronically infected promonocytic U1 cells that produce minimal or no virus. U1 cells were incub
Sensitivity and application of a new method for isolating purified compartmentalized HIV-1 unintegrated and integrated DNA.: Abstr Gen Meet Am Soc Microbiol. 1994;94:483 (abstract no. T-4). Unique Identifier : AIDSLINE ASM94/94313087; Bush CE; Golembieski A; Donovan RM; Baxa D; Markowitz N; Saravolatz LD; Henry Ford Hospital, Detroit, MI.; Measurement of the relative amounts of HIV unintegrated DNA (uDNA) and integrated DNA (iDNA) is a promising marker of therapeutic efficacy. The Hirt procedure for isolating total uDNA requires multiple extractions leading to DNA loss. We developed a novel column-based method for the isolation of cytoplasmic and nuclea
The upregulation of the promoter gene encoding the p105/p50 subunit of NF-kB by HIV is dependent upon one specific kB motif.: Abstr Gen Meet Am Soc Microbiol. 1994;94:483 (abstract no. T-5). Unique Identifier : AIDSLINE ASM94/94313088; Ten R; MacMorran W; Rolli V; Israel A; Paya C; Division of Experimental Pathology, Mayo Clinic, Rochester, MN; 55905.; Our previous cloning and sequencing of the promoter of the gene encoding the p50 subunit of NF-kB indicated that it is upregulated by NF-kB. Furthermore, we have shown that in persistently HIV-infected monocytic cells, which contain increased NF-kB activity, the transcriptional regulation of this promoter is increased
Antibody profile and isotypic patterns on HIV infected patients under drug treatment.: Abstr Gen Meet Am Soc Microbiol. 1994;94:484 (abstract no. T-11). Unique Identifier : AIDSLINE ASM94/94313089; Rivera L; Montealegre F; Diaz AM; Univ. of P.R.; In this study we correlated the isotype and specificity of the IgG antibody response from 100 Puerto Rican HIV-infected patients with the treatment which they were given. Western Blots have been performed to determine the isotype as well as protein specificity of antibodies contained in the patient s serum. Clinical d
Cellular mechanisms account for decreased anti-HIV-1 activity of nucleoside analogs.: Abstr Gen Meet Am Soc Microbiol. 1994;94:484 (abstract no. T-14). Unique Identifier : AIDSLINE ASM94/94313090; Doerr HW; Cinatl J Jr; Weber B; Cinatl J; Department of Medical Virology, J.W. Goethe University,; Frankfurt/M, Federal Republic of Germany.; We tested whether cellular mechanisms (cell resistance) may account for decreased anti-HIV-1 activity of nucleoside analogs. For this aim several MOLT-4 cell sublines were established which exerted resistance against toxic effects of nucleoside analogs including
Immune and serologic profiles of HIV-infected and non-infected hemophilic children and adolescents. HGDS.: Abstr Gen Meet Am Soc Microbiol. 1994;94:484 (abstract no. T-10). Unique Identifier : AIDSLINE ASM94/94313091; Jason J; Murphy J; Sleeper LA; Donfield SM; Warrier I; Arkin S; Evatt B; Gomperts ED; CDC, Atlanta, GA.; To assess relationships among HIV s effects on hemophilic children and adolescents immunologic parameters and vaccine-related serology, we analyzed extensive baseline immunologic evaluations of 207 HIV antibody-positive (HIV+) and 126 HIV antibody-negative (HIV-) hemophilic children and adolescents. All group compari
Plasma-levels of IL-2R and IL-6 in perinatally HIV-infected children.: Abstr Gen Meet Am Soc Microbiol. 1994;94:484 (abstract no. T-12). Unique Identifier : AIDSLINE ASM94/94313092; Fendt D; Cruciani M; Fioredda F; Loy A; Concia E; Bassetti D; Institute of Infectious Diseases, University of Verona, Italy.; OBJECTIVE: The relationship between plasma-levels of IL-2R and IL-6, known prognostic markers of HIV-infection (CD4 count, p24 antigenemia) and progression into symptomatic disease in children was investigated. METHODS: 10 children (5 male, 5 female, aged 3-7 years) with perinatal HIV-infection in different clinical s
Combination of peptide protease inhibitor and recombinant interferon-alpha A synergistically inhibited acute and chronic HIV-1 infection in vitro.: Abstr Gen Meet Am Soc Microbiol. 1994;94:485 (abstract no. T-15). Unique Identifier : AIDSLINE ASM94/94313093; Pagano PJ; Chong KT; Upjohn Laboratories, Kalamazoo, MI.; Effective treatment of human immunodeficiency virus (HIV) infections may require combinations of agents that attack different molecular targets in the viral replicative cycle. We investigated the effect of combining U-75875, a peptide protease inhibitor containing a non-hydrolyzable dihydroxyethylene isostere, with re
Dilutional analysis with a nested PCR--a method for quantitating feline immunodeficiency virus provirus in cat tissues.: Abstr Gen Meet Am Soc Microbiol. 1994;94:485 (abstract no. T-19). Unique Identifier : AIDSLINE ASM94/94313094; Read R; Nie LC; Lu YS; Richardson JA; Pakes SP; University of Texas Southwestern Medical Center, Dallas.; Most quantitative methods in PCR are subject to error due to the efficiency with which chosen primers amplify target sequences compared to reference sequences, and in some systems, the degree to which the amplified product hybridizes with a labelled probe. To quantitate provirus in biological samples, we use a highly
Feline bone marrow stromal fibroblasts are a target of feline immunodeficiency virus infection in vitro and in vivo.: Abstr Gen Meet Am Soc Microbiol. 1994;94:485 (abstract no. T-18). Unique Identifier : AIDSLINE ASM94/94313095; Lu YS; Ho SI; Read RW; Richardson JA; Pakes SP; University of Texas Southwestern Medical Center, Dallas.; Similar to HIV infection in humans, cats infected with feline immunodeficiency virus (FIV) develop anemia, neutropenia and lymphopenia. These hematologic abnormalities are thought to be due to altered marrow micro-environments because of infected marrow stromal cells. Susceptibility of marrow stromal cells to FIV infe
Genetic heterogeneity of HTLV-II infecting Italian drug abusers.: Abstr Gen Meet Am Soc Microbiol. 1994;94:485 (abstract no. T-17). Unique Identifier : AIDSLINE ASM94/94313096; Salemi M; Cimarelli A; Achilli G; Cattaneo E; Casoli C; Bertazzoni U; IGBE/CNR, Pavia, Italy.; The infection of intravenous drug users (IVDU) by the Human T-cell Leukemia virus type II (HTLV-II) has been demonstrated in North America and in Europe, frequently associated to HIV-1. We have obtained from Italian IVDUs two isolates of HTLV-II, Gu and Va, and the characterization of their genomic structure by sequen
Monoclonal antibodies to the MLV protease active site that crossreact with the HIV protease.: Abstr Gen Meet Am Soc Microbiol. 1994;94:485 (abstract no. T-16). Unique Identifier : AIDSLINE ASM94/94313097; Luftig RB; Calkins P; Yeh HY; Louisiana State University Medical Center, New Orleans.; The retroviral proteases are essential for cleavage of gag and gag-pol polyproteins during the virus assembly. Inhibitors that inactivate the protease activity will reduce production of mature particles and, thus, spread of diseases. In this study, we generated mouse monoclonal antibodies specific to protease active s
Peripheral blood and milk-derived leukocytes harbor BIV provirus.: Abstr Gen Meet Am Soc Microbiol. 1994;94:486 (abstract no. T-22). Unique Identifier : AIDSLINE ASM94/94313098; Nash JW; Hanson LA; St. Cyr Coats K; Mississippi State University.; Bovine immunodeficiency virus (BIV), a lentivirus, infects a large population of cattle in the southern United States . The mode of transmission of BIV is unknown, but its similarity to HIV suggests analogous mechanisms of transmission. The purpose of this study was to develop a PCR pro
Clostridium difficile-associated diarrhea (CDAD) in HIV positive (HIV+) patients.: Abstr Gen Meet Am Soc Microbiol. 1994;94:491 (abstract no. C-3). Unique Identifier : AIDSLINE ASM94/94313099; Fischer S; Pulvirenti J; Lisowski J; Citronberg R; Lollar R; Rice T; Goodman L; Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL.; Because the clinical course of CDAD in HIV+ pts. is not well characterized, we conducted a retrospective study of pts. with this co-infection occurring between 1/92 and 8/93 at two urban medical centers. Case definition included diarrhea (loose or watery stools), a positive HIV test, and evidence of C. difficile toxin
Association of HEp-2 cell adherent Escherichia coli with diarrhea among adults infected with HIV.: Abstr Gen Meet Am Soc Microbiol. 1994;94:544 (abstract no. C-303). Unique Identifier : AIDSLINE ASM94/94313100; Mathewson JJ; Jiang ZD; Luo N; Chintu C; Zumla A; DuPont HL; University of Texas, Houston.; Both acute and chronic diarrhea are common problems in African patients infected with the human immunodeficiency virus (HIV). There are many different agents responsible for diarrhea in this population, but a recognized cause is not found in most cases. We tested E. coli from Zambians for adherence to HEp-2 cells. Amo
Molecular epidemiology of tuberculosis in New York City.: Abstr Gen Meet Am Soc Microbiol. 1994;94:550 (abstract no. C-342). Unique Identifier : AIDSLINE ASM94/94313101; Friedman CR; Riley L; Kreiswirth B; Johnson WD; Manoach S; Sathianathan K; Stoeckle MY; Cornell University Medical College, Public Health Research; Institute, New York, N.Y.; Tuberculosis (TB) in the United States is usually due to reactivation, but may occur as a result of recent exogenous infection. Restriction Fragment Length Polymorphism (RFLP) analysis has been used to identify clonal spread of recent TB infection. We used RFLP analysis to determine th
A similar microbiologic profile in HIV-seropositive (HIV+) and seronegative (HIV-) women with pelvic inflammatory disease (PID). Multicenter HIV and PID Study Group.: Abstr Gen Meet Am Soc Microbiol. 1994;94:553 (abstract no. C-356). Unique Identifier : AIDSLINE ASM94/94313102; Moorman A; Rice R; Irwin K; O'Sullivan M; Sperling R; Brodman M; Droese A; CDC, Atlanta, GA.; To compare the microbiologic findings in HIV+ women with PID who may be immunosuppressed with those in HIV- women with PID, we started a prospective study in 1992 at two urban hospitals to evaluate women who have had PID diagnosed using standard criteria. Vaginal and endocervical secretions and endometrial biopsy tiss
Evaluation of a direct ELISA HIV-1/HIV-2 EIA using synthetic peptides: detect-HIV (version 2).: Abstr Gen Meet Am Soc Microbiol. 1994;94:554 (abstract no. C-362). Unique Identifier : AIDSLINE ASM94/94313103; Chalifour RJ; Ha NH; Barbeau S; Lacroix M; BioChem ImmunoSystems Inc., Montreal, Que., Canada.; A direct ELISA version of BioChem ImmunoSystems synthetic peptide EIA was evaluated to establish if detecting all immunoglobulin classes improves the sensitivity of this test. HRP conjugates of 3 peptides from HIV-1 GP120, HIV-1 GP41 and HIV-2 GP36 were used to detect antibodies captured by these peptides on microtit
Evaluation of a new HIV-1/HIV-2 assay.: Abstr Gen Meet Am Soc Microbiol. 1994;94:554 (abstract no. C-363). Unique Identifier : AIDSLINE ASM94/94313104; Betlach B; Hanson M; Valinsky J; Sacramento Medical Foundation Center for Blood Research, CA.; Three blood donor sites in the United States evaluated a new MicroTrak II enzyme immunoassay pending FDA approval for the detection of antibodies to HIV-1 and/or HIV-2. It was compared with licensed reference assays. Fresh samples from 10,468 volunteer
Evaluation of the Murex SUDS HIV-1 antibody test in a mixed population.: Abstr Gen Meet Am Soc Microbiol. 1994;94:554 (abstract no. C-364). Unique Identifier : AIDSLINE ASM94/94313105; Johnson JE; Ely DD; Overman SB; Goodman NL; University of Kentucky Medical Center, Lexington.; Serum specimens from 304 patients and 116 blood donors were tested for HIV-1 antibody using the Murex SUDS HIV-1 and the Genetic Systems LAV EIA test systems. There were 320 specimens non-reactive with both SUDS and LAV (116 blood donor specimens and 204 patient specimens). There were 53 patient specimens which were r
Screening a low prevalence population for HIV-2 using a combination HIV-1/HIV-2 enzyme immunoassay and an immunofluorescence assay.: Abstr Gen Meet Am Soc Microbiol. 1994;94:554 (abstract no. C-361). Unique Identifier : AIDSLINE ASM94/94313106; Zanto SN; Treichel LJ; Abbott DO; Montana Public Health Laboratory, Helena.; The Montana Public Health Laboratory has conducted screening for HIV-1 since 1985, with an estimated prevalence of HIV infection of 0.06%. To evaluate test performance and to determine the feasibility of incorporating screening for HIV-2, 2000 random serum specimens received for routine screening were tested using bot
Detection of HIV-1 proviral DNA by polymerase chain reaction using an electrochemiluminescent-tagged probe.: Abstr Gen Meet Am Soc Microbiol. 1994;94:555 (abstract no. C-367). Unique Identifier : AIDSLINE ASM94/94313107; Schutzbank TE; Smith J; Greeley C; Children's Hospital National Medical Center, Washington, D.C.; We have developed a rapid, pseudo-homogeneous assay for the detection of PCR amplicons, based on the use of electroluminescence generated from a Tris-bipyridine ruthinium (II) (Ru(bpy)3(3+)) label. PCR amplification of highly conserved HIV-1 gag gene sequences were performed using SK38/SK39 primers, where the latter w
Immunomagnetic capture of CD4+ cells from whole blood for HIV detection by PCR.: Abstr Gen Meet Am Soc Microbiol. 1994;94:555 (abstract no. C-366). Unique Identifier : AIDSLINE ASM94/94313108; Piccoli SP; Ekeze TE; Gross S; Mehta RR; Kerschner JH; Immunicon Corp., Huntingdon Valley, PA.; Rapid diagnosis of HIV infection may be greatly facilitated by direct identification of the provirus, regardless of the time course of antibody response. Toward this end, we have developed a system to permit specific isolation of CD4+ T-cells for subsequent genetic analysis by PCR. Samples of whole blood (50-75% v/v i
Polymerase chain reaction detection of HIV-1 2-LTR circular DNA may predict CD4 decline.: Abstr Gen Meet Am Soc Microbiol. 1994;94:555 (abstract no. C-368). Unique Identifier : AIDSLINE ASM94/94313109; Byrne BC; Parisi JM; Baxter JD; UMDNJ/RWJ Medical School, Camden 08103.; CD4(+)-T cell counts reflect a consequence of HIV infection but are not markers of viral activity. We seek ways to monitor aspects of HIV infection as potential tools in clinical trials of antiretroviral agents or clinical management of infected patients. HIV RNA genomes are reverse transcribed into double stranded li
VIDAS vs ELISA in the serodiagnosis of HIV 1 + 2, rubella and toxoplasma.: Abstr Gen Meet Am Soc Microbiol. 1994;94:555 (abstract no. C-365). Unique Identifier : AIDSLINE ASM94/94313110; Araj GF; Bizri AR; Fattouh LG; Nassif RE; American Univ. Med. Ctr., Beirut, Lebanon.; Rapid, automated and self-contained instruments that minimize exposure to potentially infectious blood samples are attractive addition to the serodiagnostic laboratory. The performance of Vitek Immuno Diagnostic Assay Systems (VIDAS, biomerieux Vitek Inc., Hazelwood, MO) was tried in a developing country for the detec
Pseudomonas aeruginosa bacteremia in HIV-infected patients.: Abstr Gen Meet Am Soc Microbiol. 1994;94:573 (abstract no. C-469). Unique Identifier : AIDSLINE ASM94/94313111; Gilbert L; Peters B; Peoples D; Frederick W; Howard University Hospital, Washington, DC.; In order to analyze epidemiological and clinical aspects of Pseudomonas aeruginosa bacteremia (PAB) in HIV+ patients (pts), we conducted a retrospective study of PAB during the period 1983-1993. Of the 281 pts identified, 25 (20 males, 5 females) were HIV+. Their mean age was 34.5 years and 96% were black. HIV risk fa
Pneumocystis carinii pneumonia (PCP) diagnosis and follow-up by polymerase chain reaction (PCR) in bronchoalveolar lavage (BAL) of immunocompromised patients.: Abstr Gen Meet Am Soc Microbiol. 1994;94:588 (abstract no. C-548). Unique Identifier : AIDSLINE ASM94/94313112; Moonens F; Liesnard C; Van Vooren JP; Struelens M; Erasme Hospital, Universite libre de Bruxelles, Belgium.; Several PCR protocols have been developed for the diagnosis of PCP. The aims of this study were to evaluate the sensitivity and specificity of simple and nested PCR compared with direct examination on cytospin slides after Giemsa and immunofluorescent staining, and to estimate the duration of post-PCP carriage by nest
Cloning and sequencing of the cDNA encoding Pneumocystis carinii inosine monophosphate dehydrogenase (IMPDH).: Abstr Gen Meet Am Soc Microbiol. 1994;94:590 (abstract no. F-13). Unique Identifier : AIDSLINE ASM94/94313113; O'Gara MJ; Queener SF; Lee CH; Indiana University School of Medicine, Indianapolis.; Pneumocystis carinii is an opportunistic pathogen that causes pneumonia in immunocompromised hosts. Chemotherapy is available for treating P. carinii pneumonia, but severe toxicity is a significant problem with the compounds currently considered drugs of choice. IMP dehydrogenase (IMPDH; EC 1.1.1.205) may be a good al
Genetic variation within and between human, rat and mouse-derived Pneumocystis carinii.: Abstr Gen Meet Am Soc Microbiol. 1994;94:590 (abstract no. F-10). Unique Identifier : AIDSLINE ASM94/94313114; Keely SP; Pai HJ; Sunkin SM; Baughman R; Sidman CL; Stringer SL; Stringer JR; University of Cincinnati College of Medicine, Ohio.; Pneumocystis carinii is an opportunistic pulmonary pathogen that causes P. carinii pneumonia (PCP) in immunocompromised individuals and is the major cause of death in AIDS patients. The organism thrives in a wide variety of mammals and is generally referred to as P. carinii regardless of host species. Recent reports i
Genetic and serological analysis of Pneumocystis carinii genes encoding major surface glycoprotein (MSG).: Abstr Gen Meet Am Soc Microbiol. 1994;94:597 (abstract no. F-52). Unique Identifier : AIDSLINE ASM94/94313115; Sunkin SM; Stringer SL; Stringer JR; University of Cincinnati College of Medicine, Ohio.; Pneumocystis carinii contains a large (90-120 kDa) surface glycoprotein that is recognized by antibodies in the serum of immune and infected hosts and seems to play a role in binding to host cells. Recent genetic analysis of MSG cDNAs has shown that MSG is likely to be a family of proteins. A fragment from the genome
Fungi in the gingival sulcus: frequency and speciation in HIV+ and HIV- heterosexual patients.: Abstr Gen Meet Am Soc Microbiol. 1994;94:600 (abstract no. F-70). Unique Identifier : AIDSLINE ASM94/94313116; Quart A; Gialanella P; McEachrane S; Reich D; AIDS Initiative, North Central Bronx Hospital, N.Y.; Oral candidiasis is one of the earliest and most common signs of HIV infection, suggesting that the oral cavity may be a reservoir of yeast colonization in both immunocompetent and immunosuppressed individuals. In this study 1168 samples taken from the gingival sulci of 237 Bronx methadone clinic patients were assayed
Antigen clearance for evaluation of treatment of histoplasmosis.: Abstr Gen Meet Am Soc Microbiol. 1994;94:605 (abstract no. F-95). Unique Identifier : AIDSLINE ASM94/94313117; Blair R; Garringer T; Limjoco M; Korzun A; Hafner R; Wheat J; Indiana University, Indianapolis.; Evaluation of new antifungal agents may be assisted by measurement of Histoplasma antigen clearance. We compared antigen clearance in patients treated successfully with itraconazole to that in historical controls treated with amphotericin B. Patients receiving itra were participants in an AIDS Clinical Trials Group pr
Evaluation of a human immunodeficiency virus-1 antibody immunoblot for the confirmation of oral specimens.: Abstr Gen Meet Am Soc Microbiol. 1994;94:622 (abstract no. V-29). Unique Identifier : AIDSLINE ASM94/94313118; Griffin CK; Chun JK; Allen NM; Gaudette ND; Erbling MC; Jacobs AL; Goldstein AS; Cimler BM; Epitope, Inc., Beaverton, Oregon.; Western blot (WB) assays are considered the gold standard for confirming retroviral screening test results. Specimens obtained with the OraSure oral specimen collection device have been extensively tested for the detection of antibodies to HIV and other viral infections. An HIV-1 WB was developed for the confirmation
Evaluation of the MicroTrak II HIV-1/HIV-2 recombinant antigen enzyme immunoassay.: Abstr Gen Meet Am Soc Microbiol. 1994;94:622 (abstract no. V-28). Unique Identifier : AIDSLINE ASM94/94313119; Kline R; Newhouse R; Granade T; Phillips S; Moss M; Quinn TC; Johns Hopkins Univ., Baltimore, MD.; In a study, the reliability, sensitivity, and specificity of the MicroTrak II HIV-1/HIV-2 EIA (MT II) were compared to licensed EIAs and Western Blot (WB). 2490 sera from various populations in the US, Africa, and India were evaluated at 3 different sites using the MT II and license
HIV p24 antigen (Ag) in the CSF using immune complex dissociation (ICD): correlation with p24 antibodies (Ab) in CSF, CD4, and cerebral atrophy.: Abstr Gen Meet Am Soc Microbiol. 1994;94:622 (abstract no. V-30). Unique Identifier : AIDSLINE ASM94/94313120; Valdez LM; Donovan RM; Mateo NB; Manzor O; Baxa D; Markowitz NP; Saravolatz LD; Department of Infectious Diseases, Henry Ford Hospital, Detroit,; Michigan.; The central nervous system is a major target for HIV infection. Studies have suggested that p24 Ag in the CSF is associated with the AIDS Dementia Complex (ADC). We studied 22 HIV infected patients for the presence of p24 Ag and correlated these findings with the presence of p24 Ab, cerebral atrophy by CT or MRI, and
Modulation of HIV-1 expression in monocyte derived macrophages by substance P.: Abstr Gen Meet Am Soc Microbiol. 1994;94:622 (abstract no. V-31). Unique Identifier : AIDSLINE ASM94/94313121; Ho WZ; Douglas SD; Children's Hospital of Philadelphia, PA.; The monocyte-macrophage system is a valuable in vitro model to investigate the pathogenesis of HIV-1 infection and AIDS dementia . Substance P (SP) modulates a number of important immunological functions of monocyte-macrophages. We have studied the effects of SP on HIV-1 p24 antigen
Rapid identification of Pneumocystis carinii isolates by random amplification polymorphic DNA fingerprinting.: Abstr Gen Meet Am Soc Microbiol. 1994;94:622 (abstract no. V-27). Unique Identifier : AIDSLINE ASM94/94313122; Chary-Reddy S; Graves DC; Univ. of Okla. Hlth. Sci. Ctr., Oklahoma City.; Pneumocystis carinii is an opportunistic pathogen that causes pneumonia in immunocompromised hosts including humans. It is the leading cause of morbidity and mortality in patients with AIDS. To understand more clearly the transmission of this organism, it is important to develop methods that can distinguish P. carinii
Detection of JC virus DNA by PCR in brain tissue and cerebrospinal fluid from HIV infected patients.: Abstr Gen Meet Am Soc Microbiol. 1994;94:623 (abstract no. V-36). Unique Identifier : AIDSLINE ASM94/94313123; Caldarelli Stefano R; Omodeo Zorini E; Rivolta GE; Achilli G; Cattaneo E; Vago L; Boldorini R; Ferrante P; Biology Lab., Fondazione Don C. Gnocchi IRCCS, Milano, Italy.; The correct diagnosis of progressive multifocal leukoencephalopathy (PML), a severe demyelinating disease caused from JC Virus, is of particular relevance in AIDS patients. For these reasons we set a Polymerase Chain Reaction (PCR) method to detect JCV DNA both in brain tissues collected at autopsy from 17 cases and i
Susceptibility of mice with MAIDS to cytomegalovirus retinitis at times relative to Th1/Th2 shift.: Abstr Gen Meet Am Soc Microbiol. 1994;94:623 (abstract no. V-32). Unique Identifier : AIDSLINE ASM94/94313124; Dix RD; Cray C; Cousins SW; Bascom Palmer Eye Institute, University of Miami School of; Medicine, FL.; Prior to absolute decline in CD4+ T cell number in late-stage AIDS, HIV-1 infection produces a relative immune dysregulation caused by a shift in CD4+ T helper (Th) function from a mechanism that promotes cell-mediated immunity (Th1 response) to one that favors humoral immunity (Th2 response). Theoretically, this dysr
Concomitant multiple mycobacterial infections in patients infected with HIV.: Abstr Gen Meet Am Soc Microbiol. 1994;94:624 (abstract no. V-38). Unique Identifier : AIDSLINE ASM94/94313125; Hafiz I; Pulvirenti J; Benson C; Kocka F; Cook County Hospital, Rush Medical College, Chicago, Illinois.; OBJECTIVE: Evaluate the epidemiology, clinical manifestations, and course of patients with multiple concomitant mycobacterial infections and determine associated risk factors. DESIGN: Retrospective chart review of all patients culture positive for two or more concomitant mycobacteria between 1991 and 1993. SETTING: Co
Quantitative determination of HIV-1 p24 antigen in HIV antibody positive sera following alkaline dissociation of immune complexes.: Abstr Gen Meet Am Soc Microbiol. 1994;94:624 (abstract no. V-37). Unique Identifier : AIDSLINE ASM94/94313126; Swack N; Ramirez M; Berberich S; Stapleton J; Hygienic Laboratory, Univ. of Iowa, Iowa City.; Assays for the detection of HIV-1 antigen have been used for the detection of circulating virus early in infection and also for assessment of disease progression and response to antiviral therapy. However HIV-1 p24 antigen may be complexed with HIV antibody and thus escape detection by antigen capture immunoassay. Pre
Comparison of direct fluorescence antibody and calcofluor white stain for detection of Pneumocystis carinii in respiratory specimens.: Abstr Gen Meet Am Soc Microbiol. 1994;94:625 (abstract no. V-47). Unique Identifier : AIDSLINE ASM94/94313127; Aslanzadeh J; Kowalski I; Stelmach PS; Ryan RW; University of Connecticut School of Medicine, Farmington.; Direct fluorescence monoclonal antibody stain (DFA) was compared, prospectively, with calcofluor white stain (CFW) for diagnosis of Pneumocystis carinii in 163 respiratory specimens from 97 patients. The patient population included HIV infection (58%), bone marrow transplant recipient (10%), immunosuppressed due to ch
Tuberculosis, back to the future: a multimedia presentation to complement infectious diseases lectures.: Abstr Gen Meet Am Soc Microbiol. 1994;94:628 (abstract no. W-8). Unique Identifier : AIDSLINE ASM94/94313128; Glosser W; McCandless D; Jensen L; el Sawi N; Univ. of Health Sci., Kansas City, MO.; An interactive multimedia presentation was used as a lecture-support module to communicate concepts of mycobacterial pulmonary infections to second-year medical students. The presentation was developed on the Macintosh using Macromind Director (version 3.1) authoring system. The computer generated color text and figur
Intracellular activity of roxithromycin used alone and in association with other drugs against the Mycobacterium avium complex in human macrophages.: Abstr Gen Meet Am Soc Microbiol. 1994;94:9 (abstract no. A-44). Unique Identifier : AIDSLINE ASM94/94313129; Rastogi N; Labrousse V; Bryskier A; Institut Pasteur, Point-a-Pitre, Guadeloupe, French West Indies.; Activity of roxithromycin alone or in association with ethambutol, ofloxacin, rifampin, amikacin and clofazimine against 5 clinical isolates of MAC (3 from HIV+ and 2 from HIV- patients) growing in human macrophages was assessed. Macrophage monolayers were allowed to phagocytize bacteria for 4 h at 37 degrees C. After
[Viral infections of blood mononuclear cells and regulation of the immune response]: Duodecim. 1990;106(12):913-21. Unique Identifier : AIDSLINE MED/94298562; Salonen R; Ilonen J; Salmi A; TYKS:n neurologian klinikka, Turku, Finland.
[HIV infection in a child]: Duodecim. 1990;106(12):940-5. Unique Identifier : AIDSLINE MED/94298566; Eskola J; Hiippala A; Uhari M; Auroran sairaala, lasten sisatautien osastoryhma, Helsinki,; Finland.
[AIDS and intravenous drug abuse]: Acta Psychiatr Belg. 1990 Jan-Feb;90(1):20-36. Unique Identifier : AIDSLINE MED/94310956; Schuster CR; Pickens RW; National Institute on Drug Abuse, Rockville, M.D. 20857.; The importance of intravenous drug-abuse as a vehicle of HIV and AIDS is evidenced on the basis of recent epidemiological data gathered in the USA. The rate of seropositivity among intravenous drug-addicts (whose total number i is close to one million) is estimated at more than 20 percent. Besides direct contamination
[The rheumatological manifestations of infection with the human immunodeficiency virus (HIV)]: Med Interna. 1992;44(1):40-4. Unique Identifier : AIDSLINE MED/94297939; Gheorghiu O; Suteanu S; Centrul Metodologic de Reumatologie, Bucuresti.
[HIV infection in women. Psychological and somatic obstacle]: Acta Psychiatr Belg. 1992 Mar-Apr;92(2):109-19. Unique Identifier : AIDSLINE MED/94310999; Krings M; Defourny J; Sondag-Thull D; Luminet D; Centre de Reference SIDA, Universite de Liege.; We consider the word impediment in the meaning of what compels someone, makes someone feel uncomfortable. What are the consequences/implications of seropositivity for the woman in her sexual life, in her motherhood and how does she then cope with it? The following clinical observations account for the suffering induce
[Integrated care of HIV-seropositive patients: liaison psychiatry revisited]: Acta Psychiatr Belg. 1992 Mar-Apr;92(2):78-87. Unique Identifier : AIDSLINE MED/94311000; Hirsch D; Misrachi A; Josse E; Matot JP; Service des Maladies Infectieuses, Hopital Universitaire; Saint-Pierre, ULB, Bruxelles.; Psychiatric, psychologic and psychotherapeutic care of HIV patients is integrated inside a specific medical institution. The psychological representations that AIDS mobilizes pervade the intense medical relationship between internists, nurses and the HIV patients. This relationship becomes the central node for the dif
[AIDS, burnout and fear of knowing. Dialectic observations for the benefit of clinical psychology and liaison psychiatry]: Acta Psychiatr Belg. 1992 Mar-Apr;92(2):88-92. Unique Identifier : AIDSLINE MED/94311001; Dachy V; Roelandts A; Centre de Reference SIDA, Cliniques Universitaires Saint-Luc,; Bruxelles.; A review of the literature regarding burn-out provide a sample of specific variables that describes the phenomenon. This could potentially leads to the emergence of a set of actions intending to facilitate the task of health workers (at least if personnel managers pay it attention). However, it does not preclude the r
[AIDS: challenge to liaison psychiatry. Various expectations by clinicians concerning liaison psychiatry]: Acta Psychiatr Belg. 1992 Mar-Apr;92(2):93-8. Unique Identifier : AIDSLINE MED/94311002; Gennotte AF; Centre de prise en charge, Cliniques Universitaires St-Luc,; Bruxelles.; Interdisciplinary group work could be conceived as shared common abilities in order to provide a global management of diseases. In this regard, psychologists should assumed several tasks: to advise on patient s psychological resources to keep them less anxious or more cooperative, to humanize hospital and death, to pr
[Prevalence of human immunodeficiency virus infection in a psychiatric population in Central Africa]: Acta Psychiatr Belg. 1992 Mar-Apr;92(2):99-108. Unique Identifier : AIDSLINE MED/94311003; Bleyenheuft L; Janne P; Reynaert C; Munyandamutsa N; Verhoeven F; Muremyangango B; Cassiers L; Unite de Medecine Psychosomatique, Cliniques Universitaires UCL; de Mont-Godinne.; In an African population of 292 women, hospitalised for psychiatric reasons, the seropositivity for HIV was clearly found higher than in the general corresponding population; this was particularly significant for first hospitalisations; furthermore, the seropositivity became twice as high in the group hospitalised sev
HIV-seroprevalence in the Northern Mariana Islands [letter]: Asia Pac J Public Health. 1992-93;6(4):235. Unique Identifier : AIDSLINE MED/94312194; Weinstein S
[HIV infection in ENT: risk of infection and preventive health precautions]: Laryngorhinootologie. 1994 May;73(5):291-3. Unique Identifier : AIDSLINE MED/94288864; Gurtler LG; Max von Pettenkofer Institut fur Hygiene und Med. Mikrobiologie; Universitat Munchen.; Risk of HIV transmission during the different modes of treatment depends on the HIV prevalence within the patient population and the instruments used during invasive procedures. Generally HIV may be transmitted from patient to the health care worker, from patient to patient and from health care worker to patient. Prev
World AIDS Day 1993 [news]: World Health Forum. 1994;15(2):209-10. Unique Identifier : AIDSLINE MED/94288916
Sex education essential [news]: World Health Forum. 1994;15(2):210-1. Unique Identifier : AIDSLINE MED/94288917
New research to protect against AIDS [news]: World Health Forum. 1994;15(2):211. Unique Identifier : AIDSLINE MED/94288918
Adverse effects and drug interactions of clinical importance with antiviral drugs.: Drug Saf. 1994 Apr;10(4):281-91. Unique Identifier : AIDSLINE MED/94288920; Morris DJ; Department of Pathological Sciences, Medical School, Manchester,; England.; Most antiviral drugs are nucleoside analogues with potential teratogenic, embryotoxic, carcinogenic and antiproliferative activities. They must be administered with caution during pregnancy, because some are known teratogens (e.g. amantadine) and a similar propensity cannot be entirely excluded for others (e.g. aciclo
Tenth anniversary perspectives on AIDS. FIV as a model for AIDS vaccination.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):225-8. Unique Identifier : AIDSLINE MED/94289058; Johnson CM; Torres BA; Koyama H; Yamamoto JK; Department of Comparative and Experimental Pathology, College of; Veterinary Medicine, University of Florida, Gainesville 32610.
Molecular design of CPF analogs [letter]: AIDS Res Hum Retroviruses. 1994 Mar;10(3):229-30. Unique Identifier : AIDSLINE MED/94289059; Crabbe MJ; Plater ML; Gaca M
HIV-1 virion-cell interactions: an electrostatic model of pathogenicity and syncytium formation.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):231-3. Unique Identifier : AIDSLINE MED/94289060; Callahan L
Frequent and early HIV-1MN neutralizing capacity in sera from Dutch HIV-1 seroconverters is related to antibody reactivity to peptides from the gp120 V3 domain.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):245-51. Unique Identifier : AIDSLINE MED/94289062; Zwart G; Back NK; Ramautarsing C; Valk M; van der Hoek L; Goudsmit J; Department of Virology, University of Amsterdam, The Netherlands.; The temporal development of HIV-1 neutralizing activity and antibodies to the gp120-V3 neutralization domain were studied in sera from 20 Dutch HIV-1-infected individuals followed from seroconversion on. Serum neutralizing capacity was assessed with three T cell line-tropic isolates: HIV-1MN, HIV-1HXB2, and the patien
Biological, serological, and genetic characterization of HIV-1 subtype E isolates from northern Thailand.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):263-9. Unique Identifier : AIDSLINE MED/94289064; Ichimura H; Kliks SC; Visrutaratna S; Ou CY; Kalish ML; Levy JA; Department of Medicine, School of Medicine, University of; California, San Francisco 94143-0128.; Twenty-three HIV-1 isolates were recovered from PBMCs from 26 HIV-1-seropositive individuals in northern Thailand . The viruses grew readily in human PBMCs but only 7 of 17 (41.2%) and 5 of 17 (29.4%) replicated and only at a low level in primary macrophages and in established T c
Genetic analysis of HIV-1 during rapid progression to AIDS in an apparently healthy man.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):271-7. Unique Identifier : AIDSLINE GENBANK/S73399; Oka S; Ida S; Shioda T; Takebe Y; Kobayashi N; Shibuya Y; Ohyama K; Momota K; Kimura S; Shimada K; Department of Infectious Diseases, University of Tokyo, Japan.; We encountered a case of HIV-1 infection in a previously healthy man, which was characterized by rapid progression to AIDS and death within 7 months in association with high levels of antigenemia throughout the clinical course and no humoral immune response for at least 6 months. Genetic changes of the third variable
Quantitative assessment of human immunodeficiency virus type 1 replication in human xenografts of acutely infected Hu-PBL-SCID mice.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):279-84. Unique Identifier : AIDSLINE MED/94289066; Koup RA; Hesselton RM; Safrit JT; Somasundaran M; Sullivan JL; Aaron Diamond AIDS Research Center, New York University School of; Medicine, New York 10016.; Replication of the IIIB strain of human immunodeficiency virus type 1 (HIV-1IIIB) in CB.17 scid/scid mice reconstituted with human peripheral blood lymphocytes (Hu-PBL-SCID) was investigated. Hu-PBL-SCID mice could be infected, in a dose-dependent manner, when HIV-1IIIB was injected intraperitoneally. Replication-comp
Defective infection of rabbit peripheral blood monocyte cultures with human immunodeficiency virus type 1.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):285-93. Unique Identifier : AIDSLINE MED/94289067; Tseng CK; Leibowitz J; Sell S; Department of Pathology and Laboratory Medicine, Medical School,; University of Texas Health Science Center at Houston 77225.; Human immunodeficiency virus type 1 (HIV-1) produces abortive infections of primary cultures of rabbit peripheral blood mononuclear cells (PMBCs). Mitogen activation of rabbit PBMCs or the addition of exogenous cytokines to the cultures does not change the level of release of the early HIV core protein, p24, into the
A sensitive reporter cell line for HIV-1 tat activity, HIV-1 inhibitors, and T cell activation effects.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):295-301. Unique Identifier : AIDSLINE MED/94289068; Aguilar-Cordova E; Chinen J; Donehower L; Lewis DE; Belmont JW; Institute for Molecular Genetics, Baylor College of Medicine,; Houston, Texas 77030.; The production and characterization of a cell line for quantitative HIV-1 Tat function and T cell activation assays is described. 1G5 is a clonal cell line derived from Jurkat T cells stably transfected with a luciferase gene driven by an HIV-1 long terminal repeat (HIV-LTR). The 1G5 clone was selected for low basal l
Effect of p40tax trans-activator of human T cell lymphotropic virus type I on expression of autoantigens.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):303-8. Unique Identifier : AIDSLINE MED/94289069; Banki K; Ablonczy E; Nakamura M; Perl A; Department of Medicine, State University of New York, Syracuse; 13210.; The possibility of a retroviral etiology has long been raised in a number of autoimmune disorders. More recently, Sjogren s syndrome and rheumatoid arthritis were noted in transgenic mice carrying the tax gene of human T cell leukemia virus type I (HTLV-I). To evaluate the involvement of HTLV-I Tax in autoimmunity, it
SIVmac expressing hybrid envelope proteins containing HIV-1 V3 and/or C4 sequences is not competent for replication.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):309-13. Unique Identifier : AIDSLINE MED/94289070; Kirchhoff F; Morrison HG; Murray MG; Rennert P; Desrosiers RC; New England Regional Primate Research Center, Harvard Medical; School, Southborough, Massachusetts 01772-9102.; The V3- and C4-coding regions in the envelope gene of the infectious, pathogenic SIVmac239 clone were replaced by the corresponding HIV-1 sequences. Viral particles were obtained after transfection of COS-1 cells. Chimeric SIVmac constructs were not replication competent in the human T cell lines CEMx174, AA2, H9, and
Complex splicing of simian immunodeficiency virus (mac 251-32H) rev gene transcript from infected macaques.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):315-8. Unique Identifier : AIDSLINE MED/94289071; Szotyori Z; Almond N; Kitchin P; National Institute for Biological Standards and Control, Potters; Bar, Herts, England.; Sequences of the simian immunodeficiency virus (SIV) rev mRNA transcripts were characterized from peripheral blood lymphocytes (PBLs) of two macaques experimentally infected with SIVmac251 (32H reisolate). This analysis has demonstrated that the complex splicing patterns observed for the rev mRNA transcripts originall
Silent mutation pattern in V3 sequences distinguishes virus according to risk group in Europe.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):319-20. Unique Identifier : AIDSLINE MED/94289072; Kuiken CL; Goudsmit J; Department of Virology, Academic Medical Centre, Amsterdam, The; Netherlands.
Outcome of psychoeducation for HIV risk reduction.: AIDS Educ Prev. 1994 Apr;6(2):113-25. Unique Identifier : AIDSLINE MED/94289146; Malow RM; West JA; Corrigan SA; Pena JM; Cunningham SC; University of Miami School of Medicine, FL.; Our objectives were to assess the effects of a psychoeducational (PE) program designed to reduce HIV risk behaviors in recovering drug abusers and to evaluate mediating variables associated with risk reduction as described by the AIDS Risk Reduction Model (ARRM). Consecutive admissions to a Department of Veterans Affa
AIDS prevention struggles in ethnocultural neighborhoods: why research partnerships with community based organizations can't wait.: AIDS Educ Prev. 1994 Apr;6(2):126-39. Unique Identifier : AIDSLINE MED/94289147; Stevenson HC; White JJ; University of Pennsylvania, Graduate School of Education,; Psychology in Education Division, Philadelphia 19104-6216.; Community based AIDS prevention programming and research in minority neighborhoods are growing. The AIDS epidemic has demoralized many minority communities and has added to enormously stressing social conditions. Obstacles to effective AIDS prevention programming must be removed before stable, accessible, and cultural
AIDS knowledge and sexual behavior among Mexican gay and bisexual men.: AIDS Educ Prev. 1994 Apr;6(2):163-74. Unique Identifier : AIDSLINE MED/94289150; Ramirez J; Suarez E; de la Rosa G; Castro MA; Zimmerman MA; School of Public Health, University of Michigan.; Little knowledge exists about AIDS and Human Immunodeficiency Virus (HIV) infection among Latin American gay males. In Latin America, sexual transmission from man to man is the leading cause of HIV infection. In Mexico , which ranks third in number of AIDS cases in the Americas, mor
Attitudes toward people with AIDS and implications for school-based youth AIDS education.: AIDS Educ Prev. 1994 Apr;6(2):175-83. Unique Identifier : AIDSLINE MED/94289151; Handler A; Lampman C; Levy S; Weeks K; Rashid J; Flay B; Department of Community Health Sciences, University of Illinois; at Chicago.; This study examines attitudes toward people with AIDS (PWAs) of a group of 853 7th, 8th, and 9th graders living in high-risk communities in the suburbs of a large Midwestern city. Females appear to be more tolerant than males, and whites appear to be more tolerant than other racial/ethnic groups with respect to attitu
HIV/AIDS education and prevention for Asian and Pacific Islander communities: toward the development of general guidelines.: AIDS Educ Prev. 1994 Apr;6(2):184-6. Unique Identifier : AIDSLINE MED/94289152; Yep GA; Department of Communication Studies, California State University,; Los Angeles 90032.
Psychoeducational group approach: HIV risk reduction in drug users.: AIDS Educ Prev. 1994 Apr;6(2):95-112. Unique Identifier : AIDSLINE MED/94289153; Sorensen JL; London J; Heitzmann C; Gibson DR; Morales ES; Dumontet R; Acree M; University of California, San Francisco.; In two trials of a small-group AIDS prevention approach, 50 methadone maintenance patients and 98 heroin abusers in outpatient detoxification were randomly assigned to experimental or comparison conditions. Experimental condition subjects received a 6-hour, small-group intervention that aimed to improve their knowledg
Activated T and B lymphocytes in peripheral blood of patients with Chagas' disease.: Int Immunol. 1994 Apr;6(4):499-506. Unique Identifier : AIDSLINE MED/94289330; Dutra WO; Martins-Filho OA; Cancado JR; Pinto-Dias JC; Brener Z; Freeman Junior GL; Colley DG; Gazzinelli G; Parra JC; Centro de Pesquisas Rene Rachou, FIOCRUZ, Belo Horizonte,; Brazil.; Whole blood preparations from patients with either the indeterminate (asymptomatic) or cardiac clinical forms of chronic Trypanosoma cruzi infection were analyzed by flow cytometry using double-labeling to identify subsets of circulating lymphocytes. Several significant differences were demonstrated between the blood
Fetal immunological and haematological changes in intrauterine infection [see comments]: Br J Obstet Gynaecol. 1994 May;101(5):418-21. Unique Identifier : AIDSLINE MED/94289360; Thilaganathan B; Carroll SG; Plachouras N; Makrydimas G; Nicolaides KH; Harris Birthright Research Centre for Fetal Medicine, King's; College Hospital School of Medicine, London, UK.; OBJECTIVE: To study fetal immunological and haematological changes to intrauterine infection. DESIGN: In 37 pregnancies at risk of intrauterine infection, fetal blood obtained by cordocentesis at 20 to 36 weeks gestation was used for differential leucocyte counts, platelet count, enumeration of lymphocyte subpopulatio
Sexual behavior of American adolescents: results from a U.S. national survey.: J Adolesc Health. 1994 Mar;15(2):117-25. Unique Identifier : AIDSLINE MED/94289439; Leigh BC; Morrison DM; Trocki K; Temple MT; Medical Research Institute of San Francisco, California.; PURPOSE: This paper reports on data from a 1990 U.S. national survey of the sexual behavior of male and female adolescents aged 12-17. METHODS: A household survey using a multi-stage area probability sample of the United States was undertaken in 1990. Adolescents were interviewed about
Female adolescents at high, moderate, and low risk of exposure to HIV: differences in knowledge, beliefs, and behavior.: J Adolesc Health. 1994 Mar;15(2):133-41. Unique Identifier : AIDSLINE MED/94289441; Millstein SG; Moscicki AB; Broering JM; Department of Pediatrics, University of California, San Francisco; 94143.; PURPOSE: To examine differences in the beliefs and behaviors of female adolescents at varying degrees of probable risk for HIV transmission. METHODS: A clinically-based, ethnically diverse sample of 696 sexually active female adolescents was recruited from urban and suburban general adolescent, family planning, and pu
Cognitive and behavioral adaptations to HIV/AIDS among gay and bisexual adolescents.: J Adolesc Health. 1994 Mar;15(2):142-8. Unique Identifier : AIDSLINE MED/94289442; Remafedi G; Department of Pediatrics, University of Minnesota, Minneapolis; 55455.; PURPOSE: To examine short-term changes in HIV knowledge, beliefs, and behaviors among gay and bisexual adolescents, 139 gay and bisexual male adolescents (13-21 years of age) completed interviews and self-administered surveys of HIV-related knowledge, attitudes, and behaviors during an initial assessment (Time 1) and
HIV risk behavior and medical status of underprivileged youths in Belo Horizonte, Brazil.: J Adolesc Health. 1994 Mar;15(2):179-85. Unique Identifier : AIDSLINE MED/94289448; Pinto JA; Ruff AJ; Paiva JV; Antunes CM; Adams IK; Halsey NA; Greco DB; Service of Parasitic and Infectious Diseases, School of Medicine,; Federal University of Minas Gerais, Belo Horizonte, Brazil.; METHODS: From June 1989 to April 1991, 394 adolescents aged 10-18 years randomly selected upon admission at a state shelter in Belo Horizonte, Brazil underwent health history interview, physical examination, serology for HIV, hepatitis B, and syphilis, and stool examination. Partic
Gene therapy for genetic diseases [editorial]: Hum Gene Ther. 1994 Mar;5(3):281-2. Unique Identifier : AIDSLINE MED/94289502; Anderson WF
AIDS: unanswered questions or unquestioned answers? [editorial]: Biomed Pharmacother. 1993;47(5):181-2. Unique Identifier : AIDSLINE MED/94289596; Mathe G
Levels of free purine nucleotides in continuous T-cell lines infected with virus HIV-1.: Biomed Pharmacother. 1993;47(5):207-11. Unique Identifier : AIDSLINE MED/94289602; Tabucchi A; Carlucci F; Monari P; Re MC; Furlini G; Bisozzi L; Consol-Magno E; Pizzichini M; Leoncini R; Pagani R; et al; Istituto di Biochimica e di Enzimologia, Universita di Siena,; Italy.
Effect of human immunodeficiency virus type-1 envelope glycoprotein gp160 on cytokine production from cord-blood T cells.: Blood. 1994 Jul 1;84(1):184-8. Unique Identifier : AIDSLINE MED/94289699; Than S; Oyaizu N; Pahwa RN; Kalyanaraman VS; Pahwa S; Department of Pediatrics, North Shore University Hospital-Cornell; University Medical College, Manhasset, NY 11030.; We have recently demonstrated that the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp160 enhances the in vitro differentiation of hematopoietic myeloid progenitor cells derived from cord blood by inducing secretion of colony-stimulating factor(s) (CSF) in T cells, presumably through the interacti
A plague in prostitution: HIV and AIDS in Thailand.: R I Med. 1994 May;77(5):145-9. Unique Identifier : AIDSLINE MED/94289830; Shih J; Brown University.
Symptomatic amebic colitis in a Japanese homosexual AIDS patient.: Intern Med. 1994 Feb;33(2):120-2. Unique Identifier : AIDSLINE MED/94289877; Ohnishi K; Murata M; Okuzawa E; Department of Infectious Diseases, Tokyo Metropolitan Bokutoh; General Hospital.; A 30-year-old Japanese homosexual AIDS patient was admitted to hospital because of Kaposi s sarcoma and mild diarrhea on February 4, 1993. Mud-like stool with blood and mucous was recognized after admission. Although serologic tests for Entamoeba histolytica were negative, trophozoites of E. histolytica were identifie
The need for a uniform law governing AIDS testing, reporting and confidentiality.: Trends Health Care Law Ethics. 1994 Spring;9(2):39-42. Unique Identifier : AIDSLINE MED/94289947; Tamborlane TA
Bioethics in the news....: Trends Health Care Law Ethics. 1994 Spring;9(2):4-6, 34. Unique Identifier : AIDSLINE MED/94289948; Stolman CJ
Three-dimensional 1H NMR structure of the nucleocapsid protein NCp10 of Moloney murine leukemia virus.: J Biomol NMR. 1994 Mar;4(2):153-70. Unique Identifier : AIDSLINE MED/94289983; Demene H; Jullian N; Morellet N; de Rocquigny H; Cornille F; Maigret B; Roques BP; Departemente de Pharmacochimie Moleculaire et Structurale, U266; INSERM-URA D 1500 CNRS, Faculte de Pharmacie, Paris, France.; The nucleocapsid protein of Moloney murine leukemia virus (NCp10) is a 56-amino acid protein which contains one zinc finger of the CysX2CysX4HisX4Cys form, a highly conserved motif present in most retroviruses and retroelements. At pH > or = 5, NCp10 binds one zinc atom and the complexation induces a folding of the Cy
[Status and future of infection control in gynecology and obstetrics]: Gynakol Geburtshilfliche Rundsch. 1994;34(1):52-3. Unique Identifier : AIDSLINE MED/94290029; Weissenbacher ER; Klinik und Poliklinik fur Frauenheilkunde,; Ludwig-Maximilians-Universitat Munchen, BRD.
Immunodeficiency without HIV. Clinical presentation vary [letter; comment]: BMJ. 1994 May 28;308(6941):1436. Unique Identifier : AIDSLINE MED/94290145; Monteil MA; Henderson DC; Obaro S
Immunodeficiency without HIV. Consider HIV negative immunodeficiency in cryptococcosis [letter; comment]: BMJ. 1994 May 28;308(6941):1436. Unique Identifier : AIDSLINE MED/94290146; Dev D; Basran GS; Slater D; Taylor P; Wood M
Controlling AIDS in India [letter; comment]: BMJ. 1994 May 28;308(6941):1436-7. Unique Identifier : AIDSLINE MED/94290147; Padki K
AIDS vaccine suffers setback in US [news]: BMJ. 1994 Jun 11;308(6943):1527. Unique Identifier : AIDSLINE MED/94290199; Roberts J
Recent advances in tropical medicine.: BMJ. 1994 Jun 11;308(6943):1559-62. Unique Identifier : AIDSLINE MED/94290211; Lockwood DN; Pasvol G; Department of Infection and Tropical Medicine, St Mary's Hospital; Medical School, Imperial College of Science, Technology and; Medicine, Northwick Park Hospital, Harrow.
Leiomyoma of the adrenal gland in a patient with AIDS.: Abdom Imaging. 1994 May-Jun;19(3):259-61. Unique Identifier : AIDSLINE MED/94290253; Dahan H; Beges C; Weiss L; Abitbol M; Ledreff O; Teman G; Belattar K; Rymer R; Department of Radiology, Hopital Lariboisiere, Paris, France.; Leiomyoma of the adrenal gland is an exceptional localization. We report a case occurring in a young patient with AIDS. Diagnosis was a surprise on pathologic examination. On enhanced computed tomographic (CT) scan, the adrenal mass had a low central attenuation area and a thin enhancing peripheral ring. On magnetic r
AIDS awareness in medical personnel [letter]: Natl Med J India. 1994 Mar-Apr;7(2):102. Unique Identifier : AIDSLINE MED/94290292; Bambery P; Narasimhan KL; Dilawari JB
Herpes zoster in an HIV-positive 14-month-old baby.: Natl Med J India. 1994 Mar-Apr;7(2):63-4. Unique Identifier : AIDSLINE MED/94290300; Panda S; Nabachandra T; Sarkar S; Chakraborty S; Naik TN; Deb BC; Indian Council of Medical Research Unit, Manipur.; BACKGROUND. In Manipur, a state in northeast India bordering Myanmar , within one year of reports of a high human immunodeficiency virus (HIV) seroprevalence among young injecting drug users, there has been a rapid spread of HIV infection in the
Inhibition of NF-kappa B transcription factor by catechol derivatives.: Biochem Mol Biol Int. 1994 Feb;32(2):299-305. Unique Identifier : AIDSLINE MED/94290341; Suzuki YJ; Packer L; Department of Molecular & Cell Biology, University of California,; Berkeley 94720.; Therapeutic agents which target NF-kappa B transcription factor may be useful in the management of AIDS, cancer and inflammation. Since oxidative stress has been implicated in the signaling pathway, the use of antioxidants to inhibit NF-kappa B activation has gained attention. In the present study, we examined the eff
Candida osteomyelitis.: J Foot Ankle Surg. 1994 Mar-Apr;33(2):173-6. Unique Identifier : AIDSLINE MED/94290473; Lasday SD; Jay RM; Graduate Hospital, Affiliate of the University of Pennsylvania,; Philadelphia.; Medical care of the hospital patient has become increasingly complicated due to the rising incidence of risk factors for opportunistic infection. With intravenous drug use, HIV infection, and alcoholism complicating an immunocompromised host such as a diabetic, fungal and mycobacterial infections are no longer as rare
A new approach to the limiting dilution assay.: J Biopharm Stat. 1994 Mar;4(1):101-12. Unique Identifier : AIDSLINE MED/94290523; Balch AH; Hitchcock MJ; Brockwell PJ; Bristol-Myers Squibb, PRI, Wallingford, Connecticut.; Improved methods of human immunodeficiency virus isolation have sparked an increased interest in determination of the number and proportion of infected cells in plasma samples. The limiting dilution assay is a popular method of determining the proportion of infected cells. We propose a new estimator of the proportion
[Update of anal-perineal and rectal lesions observed in AIDS]: Contracept Fertil Sex. 1994 Mar;22(3):187-94. Unique Identifier : AIDSLINE MED/94290558; Cope R; College de medecine des hopitaux de Paris.; Anorectal lesions in patients carrying the HIV virus are uncommon (13%, in our personal life, 1 women/15 men). The following raise the possibility of AIDS: Kaposi sarcoma, non Hodgkin s lymphoma and also with the young patients, intraepithelial dysplasia, in situ carcinoma or squamous carcinoma of the anus. Other anor
Pediatric acquired immunodeficiency syndrome: testing as a barrier to recognizing the role of child sexual abuse.: Arch Pediatr Adolesc Med. 1994 Jul;148(7):766-8. Unique Identifier : AIDSLINE MED/94290591; Gellert G; Berkowitz CD; Project HOPE Health Sciences Education Center, Millwood, VA; 22646.
Young people and sex/HIV education: the debate continues....: Promot Educ. 1994 Jun;1(2):21-3, 46. Unique Identifier : AIDSLINE MED/94290866; Grunseit A; National Centre for HIV Social Research (Macquarie U. Unit),; Macquarie University, North Ryde N.S.W., Australia.; The legal age of consent for heterosexual sex is 16 years. Large numbers of young people at school are sexually active. Indicators, such as sexually transmitted diseases, show that in spite of education programmes a large proportion of sexually active young people are practising unsafe sex. Access to anonymous sources
[Have you ever embraced a PWA? (person with AIDS)]: Promot Educ. 1994 Jun;1(2):36. Unique Identifier : AIDSLINE MED/94290870; Martin J; Faculte de medecine, Lausanne, Suisse.
Automat: a novel software system for the systematic search for protein (or DNA) similarities with a notable application to autoimmune diseases and AIDS.: Comput Appl Biosci. 1994 Apr;10(2):153-61. Unique Identifier : AIDSLINE MED/94290911; Cantalloube H; Nahum C; Achour A; Lehner T; Callebaut I; Burny A; Bizzini B; Mornon JP; Zagury D; Zagury JF; Universite P. et M. Curie, Paris, France.; Automat is a novel program which finds exhaustively all the oligopeptide segments shared by a given protein of any size with the proteins of a whole databank. It allows the user to collect statistics on the composition of the sequence studied in reference to the databank used. We present here the rationale and the alg
[Tumor necrosis factor (TNF) and oxygen free radicals: potential effects for immunity]: C R Seances Soc Biol Fil. 1993;187(3):296-307. Unique Identifier : AIDSLINE MED/94290960; Ferlat S; Favier A; Groupe de recherche sur les pathologies oxydatives, GREPO,; Universite de Grenoble, La Tronche.; During various biological processes as inflammation or septic shock, free radical damages are produced by a direct production of oxygen radicals by phagocytes, but also by a TNF-mediated generation in target cells. Antioxidants have been demonstrated as protective against TNF cytotoxicity. We try to measure directly t
Comparison of four commercial enzyme-linked immunosorbent and one agglutination assays for the detection of HIV antibodies in sera from Zimbabwe.: Cent Afr J Med. 1993 Oct;39(10):198-201. Unique Identifier : AIDSLINE MED/94291172; Tswana SA; Moyo SR; Nystrom L; Blomerg J; Department of Medical Microbiology, University of Zimbabwe; Medical School, Harare.; Sera from 871 AIDS and AIDS related complex patients were used to evaluate four ELISA and one agglutination assays. Commercial tests compared were Abbot, Wellcoyzyme, Biotest, Du Pont and Serodia. Wellcozyme and Serodia had the highest sensitivity (96.8 pc and 98.8 pc respectively) but the lowest specificity (53.3 pc
Long-term dietary vitamin E retards development of retrovirus-induced disregulation in cytokine production.: Clin Immunol Immunopathol. 1994 Jul;72(1):70-5. Unique Identifier : AIDSLINE MED/94291303; Wang Y; Huang DS; Eskelson CD; Watson RR; Department of Family and Community Medicine, University of; Arizona, Tucson 85724.; A 15-fold increase in dietary vitamin E (160 IU/liter) normalized hepatic and serum levels of vitamin E normally reduced by retrovirus infection. It also significantly retarded development of splenomegaly and hypergammaglobulinemia induced by retrovirus infection, while significantly restoring release of interleukin-2
Establishment and characterization of synovial cell clones with integrated human T-cell leukemia virus type-I.: Clin Immunol Immunopathol. 1994 Jul;72(1):90-7. Unique Identifier : AIDSLINE MED/94291307; Hasunuma T; Nakajima T; Aono H; Sato K; Matsubara T; Yamamoto K; Nishioka K; Division of Rheumatology and Molecular Immunology, St. Marianna; University School of Medicine, Kanagawa-ken, Japan.; Human T cell leukemia virus type-I (HTLV-I)-integrated synovial cell clones (SCCs) were established from four HTLV-I-infected patients with chronic proliferative arthropathy. Extracted DNAs of these SCCs were examined for the existence of HTLV-I proviral DNA. Electron microscopic analysis and immunohistochemical stain
Significance of interleukin 6 in patients with sarcoidosis.: Chest. 1994 Jul;106(1):156-60. Unique Identifier : AIDSLINE MED/94291373; Sahashi K; Ina Y; Takada K; Sato T; Yamamoto M; Morishita M; Second Department of Internal Medicine, Nagoya City, University; Medical School, Japan.; Interleukin 6 (IL-6) levels in various materials from patients with sarcoidosis were determined. The subjects of the study were 38 patients with sarcoidosis and 28 healthy controls. For detection of IL-6, an enzyme-linked immunosorbent assay method was used. Interleukin 6 activity in serum was detected in 4 of 30 pati
Tuberculosis in young adults and the elderly. A prospective comparison study [see comments]: Chest. 1994 Jul;106(1):28-32. Unique Identifier : AIDSLINE MED/94291394; Korzeniewska-Kosela M; Krysl J; Muller N; Black W; Allen E; FitzGerald JM; Respiratory Division, Vancouver General Hospital, BC, Canada.; OBJECTIVES: To compare the clinical, bacteriologic, and radiologic features of pulmonary and pleural tuberculosis in young adults and the elderly and determine if any differences exist between both groups. DESIGN: Prospective recruitment of all patients diagnosed as having pulmonary and pleural tuberculosis in British
Tracheoesophageal fistula in an HIV-1-positive man due to dual infection of Candida albicans and cytomegalovirus.: Chest. 1994 Jul;106(1):284-5. Unique Identifier : AIDSLINE MED/94291396; Rusconi S; Meroni L; Galli M; Clinica delle Malattie Infettive, Universita degli Studi di; Milano, Ospedale Luigi Sacco, Italy.; We report a 35-year-old HIV-1-positive man who presented with severe dyspnea and a nonproductive cough. Three fiberoptic bronchoscopic examination revealed an infiltrating and vegetating tracheal mass that was diagnosed as necrotizing candidiasis of the trachea. The lesion resulted in the formation of a tracheoesophag
[HIV-associated histoplasmosis with pulmonary manifestation in Europe]: Dtsch Med Wochenschr. 1994 Jun 24;119(25-26):909-14. Unique Identifier : AIDSLINE MED/94291508; Wockel W; Neher A; Morresi A; Pathologisches Institut, Zentralkrankenhaus Gauting der LVA; Oberbayern.; A 35-year-old man developed weight loss, lower abdominal pain, diarrhoea, cough, fever and general deterioration in his health. He had been born and resident in the USA until 1991, when he moved to Germany . Since 1991 he had known that he was HIV-positive. The chest radiograph sho
[HIV infection in children]: Dtsch Med Wochenschr. 1994 Jun 24;119(25-26):941. Unique Identifier : AIDSLINE MED/94291514
Coping and depressive symptoms among people with AIDS.: Health Psychol. 1994 Mar;13(2):156-69. Unique Identifier : AIDSLINE MED/94291613; Fleishman JA; Fogel B; Center for Gerontology and Health Care Research, Brown; University.; This study examined coping behaviors of people with AIDS, using a large sample (N = 736) that was both geographically and sociodemographically diverse. In-person interviews were conducted with people receiving AIDS-related medical or social services; follow-up interviews were conducted approximately 11 months later. F
Identification of functional sites on bovine leukemia virus envelope glycoproteins using structural and immunological data.: Eur J Biochem. 1994 Jun 1;222(2):405-14. Unique Identifier : AIDSLINE MED/94291634; Callebaut I; Portetelle D; Burny A; Mornon JP; Departement des Macromolecules Biologiques--Laboratoire de; Mineralogie-Cristallographie, CNRS URA09, Universites Paris,; France.; Sequence analysis using the sensitive hydrophobic cluster analysis method shows that the bovine leukemia virus envelope glycoproteins conserve the general organization of the influenza hemagglutinin into a stem , containing the external part of the transmembrane glycoprotein and the N-terminal and C-terminal parts of
Different proliferative response of human and chimpanzee lymphocytes after contact with human immunodeficiency virus type 1 gp120.: Eur J Immunol. 1994 Jan;24(1):34-40. Unique Identifier : AIDSLINE MED/94291738; Di Rienzo AM; Furlini G; Olivier R; Ferris S; Heeney J; Montagnier L; Department of Retroviruses, Institut Pasteur, Paris.; T cell functional defects are a common aspect of human immunodeficiency virus (HIV) infection. Moreover, it has been suggested that indirect mechanisms are involved in CD4+ cell depletion. Unresponsiveness to proliferative stimuli of lymphocytes incubated with HIV particles or with viral proteins is well documented. N
Haemochromatosis as a window into the study of the immunological system: a novel correlation between CD8+ lymphocytes and iron overload.: Eur J Haematol. 1994 May;52(5):283-90. Unique Identifier : AIDSLINE MED/94291806; Porto G; Reimao R; Goncalves C; Vicente C; Justica B; de Sousa M; Abel Salazar Institute for the Biomedical Sciences, Santo Antonio; General Hospital, Porto, Portugal.; In the present study we report a serial investigation of the numbers of the peripheral blood cells--erythrocytes, polymorphonuclear neutrophils, total lymphocytes, T-lymphocyte subpopulations (CD2, CD4, CD8), B lymphocytes and monocytes--in a group of 21 patients with haemochromatosis during the time of intensive phle
[The occurrence of immunological tolerance to inhibitors of factors VIII and IX in hemophilia patients]: Gematol Transfuziol. 1993 Feb;38(2):18-20. Unique Identifier : AIDSLINE MED/94291906; Brakman GG; To abolish inhibitors, 40 out of 60 hemophiliacs (57 patients and 3 with hemophilia A and B, respectively) were treated according to the therapeutic scheme specified as Bonn protocol. A complete disappearance of the inhibitors was achieved in all the patients. These were followed up for 13 years during which they rece
[Rapidly growing tumor of the hand--is tuberculosis as differential diagnosis gaining increased importance?]: Handchir Mikrochir Plast Chir. 1994 Mar;26(2):91-4. Unique Identifier : AIDSLINE MED/94292059; Weber P; Rosslein R; Kinderchirurgischen Universitatsklinik, Kinderspital Basel.; A two-year-old healthy, Portuguese girl presented with a prominent, painless tumor over the first web space of the left hand. The tumor increased rapidly in size over a few weeks, but caused no functional problems. On X-ray films, a cystic structure of the first metacarpal bone with erosion of the corticalis was demon
[Current developments in antiviral chemotherapy. Part 4: Foscarnet, zidovudine, didanosine]: Fortschr Med. 1994 May 10;112(13):190-1. Unique Identifier : AIDSLINE MED/94292065; Stamminger T; Fleckenstein B; Institut fur Klinische u. Molekulare Virologie der Univ.,; Erlangen.
Psychoeducation about sexual issues in an acute treatment setting.: Hosp Community Psychiatry. 1994 Apr;45(4):380-1. Unique Identifier : AIDSLINE MED/94292154; Steiner JL; Lussier RG; Maust GC; DiPalma LM; Allende MJ; Department of Psychiatry, Yale University School of Medicine, New; Haven, CT.
Oral mucosal disease: a decade of new entities, aetiologies and associations.: Int Dent J. 1994 Feb;44(1):33-43. Unique Identifier : AIDSLINE MED/94292266; Scully C; Porter SR; Centre for the Study of Oral Disease, University Department of; Oral Medicine, Surgery and Pathology, Bristol Dental Hospital and; School, UK.; New patterns of oral mucosal disease and indeed new disorders have been emerging over the past decade. Although infection with human immunodeficiency viruses (HIV) is having the most profound impact, there are also major changes in oral health and the standard of health care required, because of other new disorders an
AIDS and hepatitis: a problem for the dental team.: Int Dent J. 1994 Feb;44(1):49-54. Unique Identifier : AIDSLINE MED/94292268; Reichart PA; Department of Oral Surgery, North Free University of Berlin,; Germany.; The different types of viral hepatitis are briefly reviewed in relation to transmission during dental treatment, hepatitis B remaining the greatest threat to the dental team which is not immunised. The significance of hepatitis C for the dental profession is as yet undetermined. Transmission of HIV in the dental pract
HIV infection and AIDS: educational and ethical aspects in relation to dentistry: report from a workshop held in London, 11-13 February 1993.: Int Dent J. 1994 Feb;44(1):55-8. Unique Identifier : AIDSLINE MED/94292269; Department of Oral Pathology, School of Clinical Dentistry,; University of Sheffield, UK.
Giant molluscum contagiosum presenting as a tumor in an HIV-infected patient.: Int J Dermatol. 1994 Apr;33(4):266-7. Unique Identifier : AIDSLINE MED/94292318; Izu R; Manzano D; Gardeazabal J; Diaz-Perez JL; Dermatology Department, Hospital de Cruces, Bilbao, Spain.
[Cytomegalovirus in the etiology of bleeding stomach ulcer. Emergency endoscopy in a 70-year-old patient of unknown HIV status]: Internist (Berl). 1994 May;35(5):480-3. Unique Identifier : AIDSLINE MED/94292354; Meuthen I; Hummerich W; Kunstmann G; Kirsch L; Salzberger B; Schrappe M; Medizinische Klinik, Stadtisches Krankenhaus Koln-Holweide.
Update on legislative issues. HIV notification.: Iowa Med. 1994 May;84(5):201-2. Unique Identifier : AIDSLINE MED/94292361
Working memory in individuals with HIV infection.: J Clin Exp Neuropsychol. 1994 Apr;16(2):173-82. Unique Identifier : AIDSLINE MED/94292566; Law WA; Martin A; Mapou RL; Roller TL; Salazar AM; Temoshok LR; Rundell JR; Henry M. Jackson Foundation for the Advancement of Military; Medicine, Rockville, Maryland.; The central executive component (CE) of Baddeley s working memory model (Baddeley, 1992) was evaluated in 26 asymptomatic human immunodeficiency virus-infected individuals (HIV+) and 23 HIV-control subjects using a dual-task working memory paradigm. The HIV+ and HIV- groups showed an equivalent reduction in performanc
Oro-facial tumours in Ethiopian patients. Clinical analysis of 108 cases and a review of the literature.: J Craniomaxillofac Surg. 1994 Apr;22(2):76-80. Unique Identifier : AIDSLINE MED/94292585; Neway M; Eshete S; Minasse M; Department of Oral Maxillofacial Surgery and Dentistry, Yekatit; 12 Teaching Hospital, Addis Ababa, Ethiopia.; Maxillofacial surgery is a new medical discipline in Ethiopia . Between May 1991 and December 1992, 108 patients with maxillofacial tumours were treated in our Department. These cases are analysed according to their age, sex, anatomical site, histopathological classification of be
The relationship between type of care planning system and patient outcomes in hospitalized AIDS patients.: J Adv Nurs. 1994 Apr;19(4):691-8. Unique Identifier : AIDSLINE MED/94292668; Henry SB; Holzemer WL; Reilly CA; Department of Mental Health, Community, and Administrative; Nursing, University of California, San Francisco 94143-0608.; The purpose of this study was to describe the problems of HIV-infected patients, hospitalized for Pneumocystis carinii pneumonia (PCP), as documented in the nursing care plan and to examine differences in the number and type of activated patient problems and patient outcomes between manually generated, computer-suppor
A study on existing knowledge about AIDS among undergraduates of a Nigerian University.: J Commun Dis. 1993 Jun;25(2):52-6. Unique Identifier : AIDSLINE MED/94292705; Gugnani A; Ukeje MA; University of Nigeria Teaching Hospital, Enugu (Enugu State),; Nigeria.; This study, carried out during August-October, 1991, involved 236 respondents to a questionnaire designed to determine awareness and attitudes to AIDS and the consequent effect of such awareness on their sexual behaviour. Almost all the medical students were aware of the existence of the disease, while a few (3.8 per
HIV infection and AIDS in Latin America. Epidemiologic features and clinical manifestations.: Infect Dis Clin North Am. 1994 Mar;8(1):1-11. Unique Identifier : AIDSLINE MED/94292721; Murillo J; Castro KG; Hospital Vargas, Caracas, Venezuela.; This article updates the epidemiologic situation of HIV and AIDS infection and summarizes the most common clinical manifestations in Latin American countries. As of December 1992, a total of 59,723 AIDS cases had been reported to the Pan American Health Organization from Mexico , Ce
Human T cell lymphotropic virus type I-induced T cell activation. Resistance to TGF-beta 1-induced suppression.: J Immunol. 1994 Jul 15;153(2):566-73. Unique Identifier : AIDSLINE MED/94292786; Hollsberg P; Ausubel LJ; Hafler DA; Center for Neurologic Diseases, Brigham & Women's Hospital,; Boston, MA 02115.; T cell proliferation is potently suppressed by TGF-beta during the G1 phase of the cell cycle. The mechanism appears to involve inhibition of cell cycle kinases that phosphorylate the retinoblastoma protein (pRb), a key regulator of cell cycle progression from G1 to S phase. Although productive infection with the huma
Inhibition of activation-induced programmed cell death and restoration of defective immune responses of HIV+ donors by cysteine protease inhibitors.: J Immunol. 1994 Jul 15;153(2):862-72. Unique Identifier : AIDSLINE MED/94292818; Sarin A; Clerici M; Blatt SP; Hendrix CW; Shearer GM; Henkart PA; Experimental Immunology Branch, National Cancer Institute,; National Institutes of Health, Bthesda, MD 20892.; In vitro activation of PBLs from HIV+ individuals resulted in programmed cell death (PCD) within 2 days in 58 of 95 HIV+ blood donors, in contrast to only two of 30 control HIV- donors. CD4+ and CD8+ T cells from HIV+ donors died under these conditions, and these cells showed apoptotic nuclear morphology and DNA fragm
Projection structures of human immunodeficiency virus type 1 (HIV-1) observed with high resolution electron cryo-microscopy.: J Electron Microsc (Tokyo). 1994 Feb;43(1):16-9. Unique Identifier : AIDSLINE MED/94292879; Goto T; Ashina T; Fujiyoshi Y; Kume N; Yamagishi H; Nakai M; Department of Microbiology, Osaka Medical College, Japan.; An electron microscopical study was made of human immunodeficiency virus type 1 (HIV-1) in the unstained, frozen, hydrated state at liquid helium temperature. The findings were compared with those obtained from negative staining and ultrathin sectioning. Electron cryo-microscopy confirms and extended the findings obta
Circulating cytotoxic T lymphocyte precursors in maedi-visna virus-infected sheep.: J Gen Virol. 1994 Jul;75 ( Pt 7):1589-96. Unique Identifier : AIDSLINE MED/94292909; Blacklaws BA; Bird P; Allen D; McConnell I; Department of Veterinary Pathology, University of Edinburgh,; Summerhall, U.K.; Maedi-visna virus (MVV)-specific cytotoxic T lymphocytes (CTL) were detected, after in vitro culture with MVV antigen and recombinant human interleukin-2, in the efferent lymph and peripheral blood of sheep chronically infected with MVV. Cytotoxicity was mediated by CD8+ lymphocytes and was specific for particular str
Definition of the range and distribution of human immunodeficiency virus macrophage tropism using PCR-based infectivity measurements.: J Gen Virol. 1994 Jul;75 ( Pt 7):1597-603. Unique Identifier : AIDSLINE MED/94292910; Collin M; Illei P; James W; Gordon S; Sir William Dunn School of Pathology, University of Oxford, U.K.; The tropism of human immunodeficiency virus (HIV) for macrophages (m phi) is a well recognized phenomenon, but the range and distribution of m phi-tropic phenotypes have not been defined by quantitative means. This study uses a PCR-based infectivity assay to derive an index of m phi tropism for several common strains
Phylogenetic relationship between human immunodeficiency virus type 1 (HIV-1) long terminal repeat natural variants present in the lymph node and peripheral blood of three HIV-1-infected individuals.: J Gen Virol. 1994 Jul;75 ( Pt 7):1615-21. Unique Identifier : AIDSLINE MED/94292912; Ait-Khaled M; Emery VC; Division of Communicable Diseases, Royal Free Hospital School of; Medicine, Hampstead, London, U.K.; PCR has been used to amplify a 540 base pair fragment of the human immunodeficiency virus type 1 (HIV-1) long terminal repeat region encompassing the U5/R/U3 regions from proviral HIV DNA that was present in the lymph nodes and peripheral blood mononuclear cells of three HIV-infected individuals. The resulting PCR pro
Calcium-mediated inhibition of phorbol ester and Tax trans-activation of the human T cell leukaemia virus type 1.: J Gen Virol. 1994 Jul;75 ( Pt 7):1623-31. Unique Identifier : AIDSLINE MED/94292913; Copeland KF; Haaksma AG; Goudsmit J; Heeney JL; Department of Chronic and Infectious DiseaseS, TNO-Rijswijk, The; Netherlands.; Human Jurkat T cells containing a stably integrated human T cell leukaemia virus type 1 (HTLV-1) long terminal repeat (LTR) reporter gene construct were used to study the role of calcium-dependent cellular activation pathways in LTR trans-activation. Treatment of these cells with the calcium ionophore ionomycin result
Cerebrospinal fluid HIV-1 p24 antigen and culture: sensitivity and specificity for AIDS-dementia complex.: J Neurol Neurosurg Psychiatry. 1994 Jul;57(7):784-9. Unique Identifier : AIDSLINE MED/94292990; Brew BJ; Paul MO; Nakajima G; Khan A; Gallardo H; Price RW; Department of Neurology, Memorial Sloan-Kettering Cancer Center,; New York, NY.; We prospectively evaluated 94 patients with AIDS- dementia complex (ADC) and a smaller group of 27 patients with other HIV-1 related neurological conditions to determine the usefulness of cerebrospinal fluid (CSF) p24 antigen and HIV-1 culture in the diagnosis of ADC. The presence o
Successful immunosuppressive therapy for HTLV-I associated myelopathy.: J Neurol Sci. 1994 Apr;122(2):155-6. Unique Identifier : AIDSLINE MED/94293029; Misra AK; Mishra SK; Eigen AC; Tourtellotte WW; Neurology Service (752/127), School of Medicine, Department of; Veterans Affairs Outpatient Clinic, Los Angeles, CA.
Characterization of adherent T cells to human endothelial cells in patients with HTLV-I-associated myelopathy.: J Neurol Sci. 1994 Apr;122(2):204-9. Unique Identifier : AIDSLINE MED/94293035; Ichinose K; Nakamura T; Nishiura Y; Nagasato K; Ohishi K; Watanabe H; Fujita A; Kurouji K; Tsujihata M; Nagataki S; First Department of Internal Medicine, Nagasaki University School; of Medicine, Japan.; To clarify the phenomenon of increased adherence of T cells to endothelial cells (EC) in patients with HTLV-I-associated myelopathy (HAM), we determined the surface markers and expression of lymphocyte function antigen-1 (LFA-1) in T cells adherent or nonadherent to EC. The percentage of activated or HLA-DR+ T cells a
Appetite effect of dronabinol [letter; comment]: J Clin Oncol. 1994 Jul;12(7):1524-5. Unique Identifier : AIDSLINE MED/94293084; Beal JA
Pharmacokinetic evaluation of the combination of zidovudine and didanosine in children with human immunodeficiency virus infection.: J Pediatr. 1994 Jul;125(1):142-6. Unique Identifier : AIDSLINE MED/94293107; Mueller BU; Pizzo PA; Farley M; Husson RN; Goldsmith J; Kovacs A; Woods L; Ono J; Church JA; Brouwers P; et al; Pediatric Branch, National Cancer Institute, National Institutes; of Health, Bethesda, MD 20892.; As part of a phase I/II trial in children infected with human immunodeficiency virus, we studied the pharmacokinetics of zidovudine and didanosine administered as single agents and in combination. Zidovudine (60 to 180 mg/m2 per dose) was given orally every 6 hours, and didanosine (60 to 180 mg/m2 per dose) every 12 h
Hepatitis B vaccination in infants of mothers infected with human immunodeficiency virus.: J Pediatr. 1994 Jul;125(1):70-2. Unique Identifier : AIDSLINE MED/94293131; Zuccotti GV; Riva E; Flumine P; Locatelli V; Fiocchi A; Tordato G; Giovannini M; Fifth Pediatric Department, University of Milan, Italy.; Eighteen infants of mothers with human immunodeficiency virus (HIV) infection were given hepatitis B vaccine at birth. Seroconversion occurred in all 13 infants whose HIV antibody disappeared, versus one of five HIV-infected children. The four of five HIV-infected infants who did not mount an antibody response progres
Responses to measles immunization in children infected with human immunodeficiency virus.: J Pediatr. 1994 Jul;125(1):72-4. Unique Identifier : AIDSLINE MED/94293132; Rudy BJ; Rutstein RM; Pinto-Martin J; Division of General Pediatrics, Children's Hospital of; Philadelphia, University of Pennsylvania School of Medicine.; The responses to measles immunization administered between 6 and 12 months and after 12 months were compared in children with and without human immunodeficiency virus infection. No difference in response was found when primary measles immunization was administered between 6 and 12 months; however, children with human
Immunity to Haemophilus influenzae type b polysaccharide capsule in children with human immunodeficiency virus infection immunized with a single dose of Haemophilus vaccine.: J Pediatr. 1994 Jul;125(1):74-7. Unique Identifier : AIDSLINE MED/94293133; Peters VB; Sood SK; Department of Pediatrics, Mount Sinai School of Medicine, New; York, New York.; We studied immunity to Haemophilus influenzae type b (Hib) polysaccharide capsule in 19 children infected with human immunodeficiency virus (HIV) immunized with a single dose of a Hib vaccine at a mean age of 28 months (range, 15 to 56 months). Four to eighty-five months after immunization, only 7 children (37%) were
Antibodies to pneumococcal capsular polysaccharides in children with human immunodeficiency virus infection given polyvalent pneumococcal vaccine.: J Pediatr. 1994 Jul;125(1):77-9. Unique Identifier : AIDSLINE MED/94293134; Arpadi SM; Back S; O'Brien J; Janoff EN; Bronx Lebanon Hospital Center, New York.; Antibody to 7 common pneumococcal capsular polysaccharides was measured in 11 children with human immunodeficiency virus (HIV) infection who had been previously vaccinated with 23-valent polysaccharide pneumococcal vaccine, 11 unvaccinated children with HIV infection, and 11 healthy subjects. No differences in capsule
Effect of MTP-PE liposomes and interleukin-7 on induction of antibody and cell-mediated immune responses to a recombinant HIV-envelope protein.: J Acquir Immune Defic Syndr. 1994 Aug;7(8):799-806. Unique Identifier : AIDSLINE MED/94293161; Bui T; Dykers T; Hu SL; Faltynek CR; Ho RJ; Department of Pharmaceutics, University of Washington, Seattle; 98195.; We investigated the ability of human recombinant interleukin-7 (IL-7) to enhance the immune responses of mice vaccinated with either the alum-associated or liposome-formulated recombinant human immunodeficiency virus (HIV)-envelope protein, env-2-3SF2 (a nonglycosylated denatured gp 120 of HIV-1SF2 produced in genetic
HIV antibody testing: the gap between policy and practice.: J Acquir Immune Defic Syndr. 1994 Aug;7(8):816-22. Unique Identifier : AIDSLINE MED/94293163; Pomeroy C; Sandry J; Moldow DG; Department of Veterans Affairs Medical Center, Minneapolis, MN; 55417.; In response to recent laws regulating human immunodeficiency virus (HIV) antibody testing practices in all federal hospitals, our university-affiliated Veterans Affairs Hospital instituted several interventions designed to increase appropriate testing. Specific hospital policy requiring restriction of testing to high-
Serious Pseudomonas aeruginosa infection in AIDS.: J Acquir Immune Defic Syndr. 1994 Aug;7(8):823-31. Unique Identifier : AIDSLINE MED/94293164; Shepp DH; Tang IT; Ramundo MB; Kaplan MK; Department of Medicine, North Shore University Hospital-Cornell,; University Medical College, Manhasset, New York 11030.; During a 7-year period, 32 patients with Pseudomonas aeruginosa infection were identified on an HIV treatment service at a university-affiliated teaching hospital. The number of cases increased from 2 in 1986 to 13 in 1992. Affected patients had evidence of advanced HIV infection. In those treated with antiretroviral
Is HIV-1 likely to become a leading cause of adult mortality in sub-Saharan Africa?: J Acquir Immune Defic Syndr. 1994 Aug;7(8):839-52. Unique Identifier : AIDSLINE MED/94293166; Gregson S; Garnett GP; Anderson RM; Department of Zoology, University of Oxford, United Kingdom.; Concerns are sometimes expressed at the extent to which HIV-1 is prioritized within international and national health budgets and as a research issue, on the grounds that much larger numbers of people in developing countries currently die from other diseases, such as malaria and tuberculosis. We use a previously descr
Identification of low-level contamination of blood as basis for detection of human immunodeficiency virus (HIV) DNA in anti-HIV-negative specimens.: J Acquir Immune Defic Syndr. 1994 Aug;7(8):853-9. Unique Identifier : AIDSLINE GENBANK/L20380; Sabino EC; Delwart E; Lee TH; Mayer A; Mullins JI; Busch MP; Irwin Memorial Blood Centers, San Francisco, CA 94118.; The significance of detection of human immunodeficiency virus (HIV) DNA by the polymerase chain reaction (PCR) in seronegative or seroconverting (SC) subjects remains controversial. In a previously reported study, we identified a case in which a specimen collected 12 months before seroconversion (pre-SC) was found rep
The impact of lengthening AIDS reporting delays and uncertainty about underreporting on incidence trends and projections.: J Acquir Immune Defic Syndr. 1994 Aug;7(8):860-5. Unique Identifier : AIDSLINE MED/94293168; Bacchetti P; Department of Epidemiology and Biostatistics, University of; California, San Francisco 94143-0840.; This article extends existing methods for estimating reporting delays to allow nonparametric estimation of how delays are changing over time. Also implemented are refinements to estimate calendar month effects and to improve the accuracy of trend estimates by focusing on delays of > 6 months. Applying the method to 19
Anal intercourse and disclosure of HIV infection among seropositive gay and bisexual men.: J Acquir Immune Defic Syndr. 1994 Aug;7(8):866-9. Unique Identifier : AIDSLINE MED/94293169; Marks G; Ruiz MS; Richardson JL; Reed D; Mason HR; Sotelo M; Turner PA; Department of Preventive Medicine, University of Southern; California, Los Angeles 90033.; Human immunodeficiency virus (HIV)-infected gay and bisexual men (n = 609) randomly selected from two HIV outpatient clinics in Los Angeles completed confidential, self-administered questionnaires at the clinics, reporting sexual activities and disclosure during the previous 2 months. Approximately 9% had engaged in u
Human T-cell lymphotropic virus type I disease in Argentine intravenous drug users with human immunodeficiency virus type 1 infection [letter]: J Acquir Immune Defic Syndr. 1994 Aug;7(8):870-1. Unique Identifier : AIDSLINE MED/94293170; Zala C; Zapiola I; Bouzas MB; Benetucci J; Lopez L; Gallo D; Hanson C; Muchinik GR
Hypercalcemia in a patient with the acquired immunodeficiency syndrome and Mycobacterium avium intracellulare infection [letter]: J Acquir Immune Defic Syndr. 1994 Aug;7(8):871-2. Unique Identifier : AIDSLINE MED/94293171; Delahunt JW; Romeril KE
PCP among AIDS patients in India [letter; comment]: J Acquir Immune Defic Syndr. 1994 Aug;7(8):872-3. Unique Identifier : AIDSLINE MED/94293172; Singh YN
Impact of the AIDS epidemic on mortality of young men in Italy [letter]: J Acquir Immune Defic Syndr. 1994 Aug;7(8):873-4. Unique Identifier : AIDSLINE MED/94293173; La Vecchia C; Franceschi S; Dal Maso L; Parazzini F
Prevalence of HIV infection and other viral infections transmissible through transplantation in organ and tissue donors in France [letter]: J Acquir Immune Defic Syndr. 1994 Aug;7(8):874-6. Unique Identifier : AIDSLINE MED/94293174; Sellami F; Girard M; Larderie P; Claquin J; Lefrere JJ
Low prevalence of human T-lymphotrophic virus type I (HTLV-I) in HIV-positive patients in Kenya [letter]: J Acquir Immune Defic Syndr. 1994 Aug;7(8):876-7. Unique Identifier : AIDSLINE MED/94293175; Songok EM; Tukei PM; Libondo D; Gichogo A; Oogo SA
High HIV seroprevalence in injecting drug users in Warsaw, Poland [letter]: J Acquir Immune Defic Syndr. 1994 Aug;7(8):877-8. Unique Identifier : AIDSLINE MED/94293176; Stark K; Wirth D; Sieroslawski J; Godwod-Sikorska C; Mueller R
Predictors of HIV status among injecting drug users and health promotion.: J R Soc Health. 1994 Apr;114(2):75-80. Unique Identifier : AIDSLINE MED/94293264; Ross MW; Stowe A; Wodak A; Miller ME; Gold J; Center for Health Promotion Research and Development, School of; Public Health, University of Texas at Houston 77225.; Two consecutive samples one year apart of injecting drug users (n = 754 and n = 345) were collected in Sydney, Australia and analysed for predictors of Human Immunodeficiency Virus (HIV) prevalence. Data indicated that similar variables were associated with HIV infection in both
Anti-HIV michellamines from Ancistrocladus korupensis.: J Med Chem. 1994 Jun 10;37(12):1740-5. Unique Identifier : AIDSLINE MED/94293292; Boyd MR; Hallock YF; Cardellina JH 2nd; Manfredi KP; Blunt JW; McMahon JB; Buckheit RW Jr; Bringmann G; Schaffer M; Cragg GM; et al; Laboratory of Drug Discovery Research & Development, National; Cancer Institute-Frederick Cancer Research & Development Center,; Maryland 21702-1201.; Here we report details of the isolation and determination of the absolute configurations and comparative anti-HIV activities of novel, atropisomeric naphthylisoquinoline alkaloid dimers, michellamines A, B, and C, from a newly described species of Ancistrocladus from the Korup rainforest of
Aminodiol HIV protease inhibitors. 1. Design, synthesis, and preliminary SAR.: J Med Chem. 1994 Jun 10;37(12):1758-68. Unique Identifier : AIDSLINE MED/94293294; Barrish JC; Gordon E; Alam M; Lin PF; Bisacchi GS; Chen P; Cheng PT; Fritz AW; Greytok JA; Hermsmeier MA; Bristol-Myers Squibb Pharmaceutical Research Institute,; Princeton, New Jersey 08543-4000.; A series of HIV protease inhibitors containing a novel C2 symmetrical aminodiol core structure were prepared from amino acid starting materials. The ability of the aminodiols to inhibit HIV replication in cell culture is comparable to their ability to inhibit the is
Three-dimensional pharmacophores from binding data.: J Med Chem. 1994 Jun 10;37(12):1769-78. Unique Identifier : AIDSLINE MED/94293295; Doweyko AM; CIBA-GEIGY Corporation, Environmental Health Center, Farmington,; Connecticut 06032.; The application of HASL (hypothetical active site lattice) methodology has been successfully extended to generate putative pharmacophoric patterns in three dimensions capable of quantitatively predicting binding activity. The transformation of a HASL model to a pharmacophore is illustrated using pKi values published f
Synthesis, oral bioavailability determination, and in vitro evaluation of prodrugs of the antiviral agent 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA).: J Med Chem. 1994 Jun 10;37(12):1857-64. Unique Identifier : AIDSLINE MED/94293304; Starrett JE Jr; Tortolani DR; Russell J; Hitchcock MJ; Whiterock V; Martin JC; Mansuri MM; Bristol-Myers Squibb Company, Wallingford, Connecticut; 06492-7660.; A series of phosphonate prodrugs were evaluated in an attempt to increase the oral bioavailability of the anti-HIV agent 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA; 1). The majority of the bis(alkyl ester) and bis(alkyl amide) prodrugs were prepared by alcohol or amine displacement of dichlorophosphonate 2. Basic hydr
Crystallization and preliminary X-ray analysis of GAP 31. A protein which inhibits the life cycle of HIV-1.: J Mol Biol. 1994 Jul 1;240(1):92-4. Unique Identifier : AIDSLINE MED/94293324; Lee-Huang S; Kung HF; Chen HC; Huang PL; Rybak SM; Huang PL; Bourinbaiar AS; Musayev F; Liaw YC; Department of Biochemistry, New York University School of; Medicine, NY 10016.; GAP 31 is an anti-HIV plant protein that we have identified and purified to homogeneity from Gelonium multiflorum. It is the first reported example of an anti-HIV agent capable of acting against multiple stages of the viral life cycle, on viral infection and viral replication. GAP 31 is a unique paragon of multi-funct
Characteristics of HIV-1 gp120 glycoprotein binding to glycolipids.: J Neurosci Res. 1994 Mar 1;37(4):453-60. Unique Identifier : AIDSLINE MED/94293356; McAlarney T; Apostolski S; Lederman S; Latov N; Department of Neurology, College of Physicians and Surgeons,; Columbia University, New York, NY 10032.; We examined the binding of the gp120 envelope glycoprotein (gp120) of the human immunodeficiency virus (HIV-1) to sulfatide (GalS), galactocerebroside (GalC), and GM1-ganglioside (GM1). The gp120 glycoprotein bound to GalS but not to GalC or GM1 by enzyme-linked immunosorbent assay (ELISA) and by an immunospot assay o
[Current topics in infectious diseases]: Rinsho Byori. 1994 May;42(5):439-40. Unique Identifier : AIDSLINE MED/94293475; Igari J; Machida K; Department of Clinical Pathology, Juntendo University School of; Medicine, Tokyo.; In this symposium, we discussed the current aspects of the infectious diseases which have been becoming important problems in Japan . The following diseases were taken up the matter of MRSA infection, Helicobacter pylori infection, HIV-1 infection and HCV infection. 1) MRSA infection
[Bilateral acute retinal artery necrosis--healing of the second affected eye]: Klin Monatsbl Augenheilkd. 1994 Apr;204(4):235-40. Unique Identifier : AIDSLINE MED/94293569; Kalman A; Vogt M; Bernasconi E; Gloor B; Augenklinik, Universitatsspitales Zurich.; BACKGROUND: The acute retinal necrosis syndrome (ARN) is caused by the Varicella zoster virus or the Herpes simplex virus. However the dosage and duration of the antiviral therapy for prevention of an infection in the second eye or treatment of an infection on an affected fellow eye is still not known. We discuss the
Microvascular dynamics in normal skin versus skin overlying Kaposi's sarcoma.: Microvasc Res. 1994 Jan;47(1):140-4. Unique Identifier : AIDSLINE MED/94293811; Leu AJ; Yanar A; Jost J; Hoffmann U; Franzeck UK; Bollinger A; Department of Radiation Oncology, Edwin L. Steele Laboratory for; Tumor Biology, Massachusetts General Hospital, Harvard Medical; School, Boston 02114.
Alkaloidal glycosidase inhibitors (AGIs) as the cause of sporadic scrapie, and the potential treatment of both transmissible spongiform encephalopathies (TSEs) and human immunodeficiency virus (HIV) infection.: Med Hypotheses. 1994 Feb;42(2):69-75. Unique Identifier : AIDSLINE MED/94293839; Dealler S; York District Hospital Microbiology Department, UK.; AGIs are produced by plants and microorgansims in the environment. They are absorbed from the gut, distributed throughout the body and are concentrated inside cells. AGIs alter the glycan chains of cellular glycoproteins (CGP) during their formation so that the same CGP produced by different clones of cells (and hence
Zidovudine and the quality of life [letter; comment]: N Engl J Med. 1994 Aug 4;331(5):332-3. Unique Identifier : AIDSLINE MED/94293993; Berman DS; Wenglin BD
Racial differences in the use of drug therapy for HIV disease [letter; comment]: N Engl J Med. 1994 Aug 4;331(5):333-4. Unique Identifier : AIDSLINE MED/94293994; Simon PA; Sorvillo FJ; Lapin RK
Why women lead the incidence stakes in AIDS.: Nurs RSA. 1994 Jun;9(6):16, 18-9. Unique Identifier : AIDSLINE MED/94294007; van Niftrik J
France wins larger share of patent royalties after AIDS test dispute [news]: Nature. 1994 Jul 14;370(6485):85. Unique Identifier : AIDSLINE MED/94294025; Macilwain C
AIDS policy chief quits after criticism [news]: Nature. 1994 Jul 14;370(6485):89. Unique Identifier : AIDSLINE MED/94294028
AIDS update [news]: N Z Med J. 1994 Jul 13;107(981):277. Unique Identifier : AIDSLINE MED/94294135
[Visceral form of human anthrax imported from Africa]: Presse Med. 1994 Mar 12;23(10):477-8. Unique Identifier : AIDSLINE MED/94294309; Paulet R; Caussin C; Coudray JM; Selcer D; de Rohan Chabot P; CHG, Longjumeau.; Widespread vaccination has largely eliminated anthrax in Europe (the last case was reported in France in 1972) but the disease remains endemic in many developing countries. The usual cutaneous presentation (malignant pustules) is much more familiar than the various visceral manifes
Acute pancreatitis related to octreotide in a patient with acquired immunodeficiency syndrome [letter]: Pancreas. 1994 May;9(3):395-7. Unique Identifier : AIDSLINE MED/94294355; Vidal J; Sacanella E; Munoz E; Miro JM; Navarro S
Empirical and rational approaches for development of inhibitors of the human immunodeficiency virus--HIV-1.: Pharmacol Ther. 1993 Nov;60(2):315-29. Unique Identifier : AIDSLINE MED/94294482; Prusoff W; Lin TS; Pivazyan A; Sun AS; Birks E; Department of Pharmacology, Yale University, New Haven, CT 06510.; The human immunodeficiency virus, HIV-1, is generally accepted to be responsible for AIDS. It is imperative that all approaches, empirical and rational, be taken for development of a drug for therapy of this disease. These approaches are discussed, with emphasis on the direction being pursued in our laboratory. Empiri
Tuberculosis in the 1990's.: Radiol Clin North Am. 1994 Jul;32(4):649-61. Unique Identifier : AIDSLINE MED/94294597; Miller WT; Department of Radiology, Hospital of the University of; Pennsylvania, Philadelphia.; Tuberculosis, an ancient disease undergoing recent control by public hygiene and drug therapy, has experienced a recrudescence in the United States . Factors leading to the increased incidence of tuberculosis include the high incidence of tuberculosis among the AIDS population, an incre
High-resolution computed tomography in acute diffuse lung disease in the immunocompromised patient.: Radiol Clin North Am. 1994 Jul;32(4):731-44. Unique Identifier : AIDSLINE MED/94294602; Primack SL; Muller NL; Oregon Health Sciences University, Portland.; A number of studies have shown that high-resolution CT (HRCT) scanning may be helpful in the assessment of acute diffuse lung disease in immunocompromised patients. HRCT may demonstrate abnormalities when the radiograph is normal and may allow for a more confident diagnosis in patients with nonspecific radiographic fi
[HIV infection, fever and cholestasis (clinical conference)]: Schweiz Rundsch Med Prax. 1994 Jun 14;83(24):757-60. Unique Identifier : AIDSLINE MED/94294694; Giezendanner S; Zala G; Jost J; Greminger P; Meyenberger C; Departement fur Innere Medizin, Universitatsspital Zurich.; A 35-year-old Swiss woman with AIDS experienced fever, jaundice and cough. Laboratory evaluation revealed signs of an infection and cholestasis. The examination by ultrasound showed thickening of the intra- and extrahepatic bile ducts and gallbladder wall, without dilatation or stones. Endoscopic retrograde cholangiog
[Has the age of onset of sexual activity in youths changed in the time of AIDS? Literature review 1972-1992]: Schweiz Med Wochenschr. 1994 Jun 18;124(24):1047-55. Unique Identifier : AIDSLINE MED/94294740; Koffi-Blanchard MC; Dubois-Arber F; Michaud PA; Narring F; Paccaud F; Unite d'evaluation de programmes de prevention/Institut; universitaire de medecine sociale et preventive, Lausanne.; This article on the sexuality of adolescents (aged 16 to 20) presents results of a secondary analysis of Swiss studies completed on the subject between 1972 and 1992. The aim of the study was to follow up the evolution of three aspects of sexual behaviour since 1972 as a contribution to answering the following questio
HIV disease: medical and dental aspects and trends for the future. A literature review.: Schweiz Monatsschr Zahnmed. 1994;104(5):565-77. Unique Identifier : AIDSLINE MED/94294746; Migliorati CA; Koller MM; Public Oral Health Clinic Zurich.; The pandemic dimension of HIV disease is a reality. The cases of acquired immunodeficiency syndrome (Aids) and of new infections with HIV continue to increase. Available antiretroviral therapy cannot halt the progress of the disease. However, because of early diagnosis and treatment, life expectancy has increased. Ora
[AIDS: obscene announcement (news)]: Schweiz Monatsschr Zahnmed. 1994;104(5):694. Unique Identifier : AIDSLINE MED/94294756
Cytokine patterns during the progression to AIDS [comment]: Science. 1994 Jul 8;265(5169):193-4. Unique Identifier : AIDSLINE MED/94294783; Mosmann TR; Department of Immunology, University of Alberta, Edmonton,; Canada.
Ability of HIV to promote a TH1 to TH0 shift and to replicate preferentially in TH2 and TH0 cells [see comments]: Science. 1994 Jul 8;265(5169):244-8. Unique Identifier : AIDSLINE MED/94294788; Maggi E; Mazzetti M; Ravina A; Annunziato F; de Carli M; Piccinni MP; Manetti R; Carbonari M; Pesce AM; del Prete G; et al; Division of Clinical Immunology and Allergy, University of; Florence, Italy.; Both interferon gamma (IFN-gamma) produced by T helper 1 (TH1) lymphocytes and interleukin-4 (IL-4) produced by TH2 lymphocytes were reduced in either bulk circulating mononuclear cells or mitogen-induced CD4+ T cell clones from the peripheral blood of individuals infected with human immunodeficiency virus (HIV). Ther
Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals [see comments]: Science. 1994 Jul 8;265(5169):248-52. Unique Identifier : AIDSLINE MED/94294789; Graziosi C; Pantaleo G; Gantt KR; Fortin JP; Demarest JF; Cohen OJ; Sekaly RP; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.; A switch from a T helper 1 (TH1) cytokine phenotype to a TH2 phenotype has been proposed as a critical element in the progression of human immunodeficiency virus (HIV) disease. Here, constitutive cytokine expression was analyzed in unfractionated and sorted cell populations isolated from peripheral blood and lymph nod
Resistance to murine acquired immunodeficiency syndrome (MAIDS) [letter; comment]: Science. 1994 Jul 8;265(5169):264-6; discussion 267. Unique Identifier : AIDSLINE MED/94294795; Morawetz RA; Doherty TM; Giese NA; Hartley JW; Muller W; Kuhn R; Rajewsky K; Coffman R; Morse HC 3rd
AIDS blood-test royalties. NIH-Pasteur: a final rapprochement? [news]: Science. 1994 Jul 15;265(5170):313. Unique Identifier : AIDSLINE MED/94294798; Cohen J; Marshall E
An anti-HIV vitamin? [news]: Science. 1994 Jul 15;265(5170):315. Unique Identifier : AIDSLINE MED/94294800
Risking everything? Risk behavior, behavior change, and AIDS [see comments]: Science. 1994 Jul 15;265(5170):341-5. Unique Identifier : AIDSLINE MED/94294805; Aggleton P; O'Reilly K; Slutkin G; Davies P; Global Programme on AIDS, World Health Organization, Geneva,; Switzerland.; Inquiry into the determinants of risk-related sexual behavior is important for the development of interventions to reduce the incidence of new cases of human immunodeficiency virus infection. Recent social and behavioral research has revealed much about the individual and social factors influencing risk-taking. Findin
The politics of AIDS. Introduction.: Soc Sci Med. 1994 May;38(10):1321-4. Unique Identifier : AIDSLINE MED/94294835; Singer M; Hispanic Health Council, Hartford, CT 06106.; From its first designation as a gay plague, HIV/AIDS has been a heavily politicized disease, a disease that has fractured official standard operating procedures in science, medicine, public health and governance. In many ways, AIDS helped to expose a battleground of contested interests while emerging as an arena for b
The impact of HIV/AIDS on concepts relating to risk and culture within British community epidemiology: candidates or targets for prevention.: Soc Sci Med. 1994 May;38(10):1325-35. Unique Identifier : AIDSLINE MED/94294836; Frankenberg RJ; Keele University, Staffordshire, U.K.; The social and cultural responses to the AIDS/HIV epidemic focus attention both on the limitations of reification in biomedicine and on the deficiencies of many interpretations of culture in anthropology. Within clinical medicine the focus on disease and isolated aspects of the patient s somatic body alienates the pat
Risky business: the cultural construction of AIDS risk groups.: Soc Sci Med. 1994 May;38(10):1337-46. Unique Identifier : AIDSLINE MED/94294837; Schiller NG; Crystal S; Lewellen D; Department of Anthropology, University of New Hampshire, Durham; 03824.; AIDS researchers and policy makers have often employed the concept of culture to characterize high risk groups and explain why members of these groups continue to practice risky behavior. We argue that the widespread interest in ethnography tends to reflect a usage of the concept of culture that distances and su
Blastomycosis and human immunodeficiency virus: three new cases and review.: South Med J. 1994 Jul;87(7):715-9. Unique Identifier : AIDSLINE MED/94294860; Witzig RS; Hoadley DJ; Greer DL; Abriola KP; Hernandez RL; Department of Medicine, Tulane University School of Medicine, New; Orleans, LA 70112.; Reports of blastomycosis in individuals infected with the human immunodeficiency virus (HIV) are increasing. We report on 3 patients co-infected with blastomycosis and HIV (to add to the previously reported 21), and review important clinical aspects and outcomes in all cases. The percentage of patients co-infected wit
HIV-negative AIDS in Kentucky: a case of idiopathic CD4+ lymphopenia and cryptococcal meningitis.: South Med J. 1994 Jul;87(7):751-2. Unique Identifier : AIDSLINE MED/94294868; Ramirez JA; Srinath L; Ahkee S; Huang AK; Raff MJ; Department of Medicine, University of Louisville, School of; Medicine, KY 40292.; Here we describe a case of unexplained CD4+ T-lymphocyte depletion and cryptococcal meningitis in a patient without evidence of human immunodeficiency virus (HIV) infection. This newly recognized syndrome has been named idiopathic CD4+ lymphopenia (ICL). When HIV infection is suspected in a patient with an opportunist
African American women and AIDS: a public health/social work challenge.: Soc Work Health Care. 1994;19(3-4):123-43. Unique Identifier : AIDSLINE MED/94294894; Dicks BA; University of Connecticut, School of Social Work, West Hartford; 06117.; AIDS is a global problem affecting people regardless of economic status, ethnicity, age, occupation, or gender. Although, initially perceived as a gay men s disease, the fastest growing population in the AIDS epidemic is women. African American women represent over half the reported cases of AIDS among women in the
Women's health issues: a review of the current literature in the social work journals, 1985-1992.: Soc Work Health Care. 1994;19(3-4):145-72. Unique Identifier : AIDSLINE MED/94294895; Millner L; Widerman E; Temple University, School of Social Administration, Philadelphia,; PA 19122.; To assess the ways in which social work is addressing issues in women s health care, the profession s journals from 1985-1992 were searched, yielding 36 articles. Over half addressed issues of reproduction and sexuality including pregnancy, family planning, abortion, substance abuse in pregnancy, and fetal protection
[Working environment--weak with terror (interview by Mads Gudiksen)]: Sygeplejersken. 1993 Oct 13;93(41):13. Unique Identifier : AIDSLINE MED/94294947; Lauritsen A
[Working environment--negligent about safety]: Sygeplejersken. 1993 Oct 13;93(41):14, 31. Unique Identifier : AIDSLINE MED/94294948; Gudiksen M
Transfusion transmission of retroviruses: human T-lymphotropic virus types I and II compared with human immunodeficiency virus type 1.: Transfusion. 1994 Jun;34(6):478-83. Unique Identifier : AIDSLINE MED/94295061; Donegan E; Lee H; Operskalski EA; Shaw GM; Kleinman SH; Busch MP; Stevens CE; Schiff ER; Nowicki MJ; Hollingsworth CG; et al; University of California, San Francisco.; BACKGROUND: The incidence of transfusion transmission of human T-lymphotropic virus type I (HTLV-I) and HTLV type II (HTLV-II) has not been compared directly or to that of human immunodeficiency virus type 1 (HIV-1). The effects of refrigerator storage of the blood component on infectivity of the viruses needs definit
A review of transfusion-associated AIDS litigation: 1984 through 1993 [see comments]: Transfusion. 1994 Jun;34(6):484-91. Unique Identifier : AIDSLINE MED/94295062; Kern JM; Croy BB; San Francisco office of the law firm Crosby, Heafey, Roach & May,; California.; BACKGROUND: Since 1984, hundreds of lawsuits have been filed against health care providers in the United States , alleging transmission of human immunodeficiency virus by transfusion. While anecdotal reports of jury verdicts have been published, no quantitative study to identify trends
Differential sensitivities of viruses in red cell suspensions to methylene blue photosensitization.: Transfusion. 1994 Jun;34(6):521-6. Unique Identifier : AIDSLINE MED/94295069; Wagner SJ; Robinette D; Storry J; Chen XY; Shumaker J; Benade L; Product Development Department, Jerome H. Holland Laboratory,; American Red Cross Blood Services, Rockville, Maryland.; BACKGROUND: Previous studies explored the feasibility of using the photosensitizer methylene blue (MB) as a virucidal agent in red cell suspensions. Under treatment conditions (5 microM [5 mumol/L] MB, 3.4 x 10(4) J/m2) that resulted in more than 6 log10 inactivation of vesicular stomatitis virus (VSV) or of the envel
Controversy in transfusion medicine: use of external controls in transmissible disease testing: pro [see comments]: Transfusion. 1994 Jun;34(6):550-1. Unique Identifier : AIDSLINE MED/94295075; Linden JV; Wethers J; Dressler KP; Wadsworth Center for Laboratories and Research, New York State; Department of Health, Albany.
Controversy in transfusion medicine: use of external controls in transmissible disease testing: con [see comments]: Transfusion. 1994 Jun;34(6):552-3. Unique Identifier : AIDSLINE MED/94295076; Epstein JS; Division of Transfusion-Transmitted Diseases, Food and Drug; Administration, Bethesda, Maryland.
[HIV-positive drug addicts treated at the Copenhagen City Drug Dependency Clinic 1986-1992]: Ugeskr Laeger. 1994 May 16;156(20):3028-32. Unique Identifier : AIDSLINE MED/94295096; Hjorther AB; Andersen LB; Hetmar O; Jepsen PW; Psykiatrisk afdeling, Kommunehospitalet, Kobenhavn.; The Copenhagen City Drug Dependency Clinic at the former Rudolph Bergh s Hospital was established in 1986 as part of the measures taken by the municipality of Copenhagen to control the spread of HIV/AIDS among the intravenous drug addicts in the City of Copenhagen. The aim was to attract those HIV-positive drug addict
[Flow cytometry in routine hematologic analysis (editorial)]: Wien Klin Wochenschr. 1994;106(8):225. Unique Identifier : AIDSLINE MED/94295205; Bauer K
[Report of initial experiences in establishing a regional multicenter evaluation of lymphocyte typing with flow cytometry]: Wien Klin Wochenschr. 1994;106(8):247-9. Unique Identifier : AIDSLINE MED/94295210; Schonwald E; Jilch R; Serodiagnostische Station der Dermatologischen Abteilung des; Krankenhauses der Stadt Wien-Lainz.; Participation in a multicenter evaluation of flowcytometric investigations is the only possibility of providing external quality control. Up to now nine different laboratories have taken part in this program, measuring two samples of fresh EDTA blood according to a recommended antibody panel. The choice of antibodies
Immunogenicity of synthetic HIV-1 gp120 V3-loop peptide-conjugate immunogens.: Vaccine. 1994 Apr;12(5):445-51. Unique Identifier : AIDSLINE MED/94295251; Conley AJ; Conard P; Bondy S; Dolan CA; Hannah J; Leanza WJ; Marburg S; Rivetna M; Rusiecki VK; Sugg EE; et al; Department of Virus and Cell Biology, Merck Research; Laboratories, West Point, PA 19486.; A successful prophylactic human immunodeficiency virus type 1 (HIV-1) vaccine must elicit an immune response that will prevent establishment of the persistent viral infection. The only response shown to be effective in this regard is virus-neutralizing antibody directed against the viral gp120 hypervariable V3-loop re
HIV immunotherapy [letter] [published erratum appears in Vaccine 1994 Aug;12(11):1055]: Vaccine. 1994 Apr;12(5):476. Unique Identifier : AIDSLINE MED/94295258; Slade HB
[Immunologic parameters in women with normal pregnancy and pre-eclampsia]: Zentralbl Gynakol. 1994;116(5):260-2. Unique Identifier : AIDSLINE MED/94295322; Bettin S; Halle H; Wenzkowski BM; Volk HD; Jahn S; Frauenklinik der Charite, Universitatsklinikum Berlin.; Immunological investigations were carried in women with normal pregnancy and patients with preeclampsia. Regarding the lymphocyte subpopulation distribution an elevated number of T lymphocytes, especially of CD-4 carrying helper-inducer T cells, was registered resulting in an altered CD4/CD8 ratio. The T lymphocytes i
Immunoglobulin VH3-positive AIDS-related Burkitt's lymphoma: a possible role for the HIV gp120 superantigen.: Acta Haematol. 1994;91(2):103-5. Unique Identifier : AIDSLINE MED/94295346; Amariglio N; Vonsover A; Hakim I; Neumann Y; Mark Z; Brok-Simoni F; Ben-Bassat I; Rechavi G; Institute of Hematology, Chaim Sheba Medical Center,; Tel-Hashomer, Israel.
Peripheral T-cell lymphoma of the scrotum.: Acta Haematol. 1994;91(2):77-9. Unique Identifier : AIDSLINE MED/94295356; Doll DC; Diaz-Arias AA; Department of Medicine, Veterans Administration Hospital,; Columbia, Mo 65201.; Primary lymphoma of the scrotum is rare. We report a case of primary immunoblastic lymphoma of the scrotum in a homosexual who was negative for antibodies to human immunodeficiency virus. Immunoperoxidase stains of paraffin-embedded tissue were consistent with a T-cell phenotype. Although complete remission was initia
Prostaglandin E2 suppresses phytohemagglutinin-induced immune responses of normal human mononuclear cells by decreasing intracellular glutathione generation, but not due to increased DNA strand breaks or apoptosis.: Agents Actions. 1993 Nov;40(3-4):191-9. Unique Identifier : AIDSLINE MED/94295468; Yu CL; Liu CL; Tsai CY; Sun KH; Liao TS; Lin WM; Chen HL; Yu HS; Department of Medicine, Veterans General Hospital-Taipei, Taiwan,; Republic of China.; Prostaglandin E2 (PGE2) at concentrations more than 1 x 10(-8) M markedly suppressed the cell proliferation and release of soluble molecules of interleukin-2 receptor (sIL-2R), CD4 (sCD4) and CD8 (sCD8) from phytohemagglutinin (PHA)-stimulated normal human mononuclear cells (MNC) in a dose-related manner. To further e
Prognostic indicators in adult cerebral malaria: a study in Burundi, an area of high prevalence of HIV infection.: Acta Trop. 1994 Apr;56(4):299-305. Unique Identifier : AIDSLINE MED/94295478; Niyongabo T; Deloron P; Aubry P; Ndarugirire F; Manirakiza F; Muhirwa G; Ndayiragije A; Brelivet JC; Centre Hospitalo-Universitaire de Kamenge, Bujumbura, Burundi.; We examined the possible risk factors for poor prognostic in cerebral malaria in 31 adults from Burundi , an area of high prevalence rate of HIV-1 infection. Depth of coma, temperature, vomiting, seizures, parasite load, or anaemia did not modify the outcome. High levels of creatin
Demographic differences in cumulative incidence rates of transfusion-associated acquired immunodeficiency syndrome.: Am J Epidemiol. 1994 Jul 15;140(2):105-12. Unique Identifier : AIDSLINE MED/94295534; Selik RM; Ward JW; Buehler JW; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, GA 30333.; To describe the demographic patterns of blood transfusion in the United States , the authors analyzed the cumulative incidence rate of transfusion-associated acquired immunodeficiency syndrome (AIDS) (total cases reported from June 1981 through May 1993 per million population) by sex, r
Outbreak of multi-drug-resistant tuberculosis in a New York State prison, 1991.: Am J Epidemiol. 1994 Jul 15;140(2):113-22. Unique Identifier : AIDSLINE MED/94295535; Valway SE; Richards SB; Kovacovich J; Greifinger RB; Crawford JT; Dooley SW; Division of Tuberculosis Elimination, Centers for Disease Control; and Prevention, Atlanta, GA 30333.; In the summer of 1991, four inmates from prison A in Upstate New York died of multi-drug-resistant tuberculosis. To determine the extent of resistant tuberculosis at prison A and transmission patterns, the authors interviewed staff and reviewed medical records and inmate movement histories. Contact investigation resul
Re: Differences in risk factors for human immunodeficiency virus type 1 seroconversion among male and female intravenous drug users [letter; comment]: Am J Epidemiol. 1994 Jul 15;140(2):188-90. Unique Identifier : AIDSLINE MED/94295544; Nicolosi A
Profound reversible CD4+ T lymphocytopenia in a severely uremic patient.: Am J Kidney Dis. 1994 Jul;24(1):89-91. Unique Identifier : AIDSLINE MED/94295566; Polsky FI; Dannemann B; Hemmert WH; Department of Internal Medicine, Utah Valley Regional Medical; Center, Provo 84604.; We report a human immunodeficiency virus antibody-negative, profoundly uremic patient who presented with a CD4+ T lymphocyte count of 133/mm3, a CD8+ T lymphocyte count of 77/mm3, and a CD3+ T lymphocyte count of 259/mm3. These values decrease significantly below reported levels in other lymphopenic uremic patients. H
A quantitative and cartographic study of retinal microvasculopathy in acquired immunodeficiency syndrome.: Am J Ophthalmol. 1994 Jul 15;118(1):46-56. Unique Identifier : AIDSLINE MED/94295622; Glasgow BJ; Weisberger AK; Jules Stein Eye Institute, Los Angeles, CA 90024.; We quantified the retinal microvascular abnormalities in 57 eyes from autopsy patients with the acquired immunodeficiency syndrome (AIDS) and in 24 eyes from gender- and age-matched control subjects. We related retinal vascular changes to the topography of cytomegalovirus retinitis
American cutaneous leishmaniasis: in situ characterization of the cellular immune response with time.: Am J Trop Med Hyg. 1994 Jun;50(6):743-7. Unique Identifier : AIDSLINE MED/94295850; Lima HC; Vasconcelos AW; David JR; Lerner EA; Nucleo de Medicina Tropical, Universidade Federal do Ceara,; Fortalez, Brazil.; The cellular nature of the infiltrate in the skin of patients with American cutaneous leishmaniasis was characterized by immunohistochemistry. The study population consisted of patients in Ceara, Brazil , an area where Leishmania braziliensis is endemic. Biopsies were taken from les
Repeated stellate ganglion blockade using a catheter for pediatric herpes zoster ophthalmicus [see comments]: Anesthesiology. 1994 Apr;80(4):950-2. Unique Identifier : AIDSLINE MED/94295942; Elias M; Chakerian MU; Department of Anesthesiology, University of California, San Diego; Medical Center 92103-8812.
Cationic liposomes for direct gene transfer in therapy of cancer and other diseases.: Ann N Y Acad Sci. 1994 May 31;716:23-34; discussion 34-5. Unique Identifier : AIDSLINE MED/94295994; Farhood H; Gao X; Son K; Yang YY; Lazo JS; Huang L; Barsoum J; Bottega R; Epand RM; Department of Pharmacology, University of Pittsburgh School of; Medicine, Pennsylvania 15261.; Cationic liposomes can mediate efficient delivery of DNA and DNA/protein complex to mammalian cells in vitro and in vivo. Cationic cholesterol derivatives mixed with phosphatidylethanolamine and sonicated to form small unilamellar vesicles can complex with DNA and mediate the entry into the cytosol from the endosome c
[Primary renal lymphoma in an HIV-positive patient]: Arch Esp Urol. 1994 Apr;47(3):287-9. Unique Identifier : AIDSLINE MED/94296150; Garcia Freire C; Busto Castanon L; Pombo Felipe F; Guitian Barreiro D; Loureiro Santamaria C; Gonzalez Martin M; Servicio de Urologia, Hospital Juan Canalejo, La Coruna,; Espana.; We report on an HIV positive patient with bilateral primary renal non-Hodgkin lymphoma that remitted with chemotherapy. The clinical and radiological features, which are initially not distinct from those of other tumors in the same site, and the therapeutic possibilities are discussed.
[Acute Staphylococcus aureus myocarditis in AIDS. 2 cases]: Arch Mal Coeur Vaiss. 1993 Dec;86(12):1765-8. Unique Identifier : AIDSLINE MED/94296193; Hofman P; Michiels JF; Rosenthal E; Tran AT; Taillan B; Ferrari E; Loubiere R; Service d'anatomie pathologique, hopital Pasteur, Nice.; The authors report two cases of acute myocarditis due to Staphylococcus aureus in patients with AIDS. There was no history of opportunist infections in either case but the CD4 lymphocyte levels were very low. The myocarditis caused acute cardiac failure and death. Histological examination showed microabscesses filled
CD8+ polylobated T-cell leukemia/lymphoma. A case report with immunophenotypic, ultrastructural, gene rearrangement, karyotypic, and DNA content analysis and autopsy description.: Arch Pathol Lab Med. 1994 Jul;118(7):722-7. Unique Identifier : AIDSLINE MED/94296223; Friedman HD; Hutchison RE; Smith JR; Gonchoroff NJ; Stein CK; Poiesz BJ; Department of Pathology and Laboratory Medicine, Syracuse, NY; 13210.; Polylobated lymphoma is a morphologic variant of malignant lymphoma characterized by large pleomorphic neoplastic cells with polylobated nuclei. We report an unusual case in a 57-year-old man with a 9-year history of an antecedent low-grade peripheral T-cell lymphoma with dermal involvement. The polylobated lymphoma e
Placental cryptococcosis in a mother with systemic lupus erythematosus.: Arch Pathol Lab Med. 1994 Jul;118(7):757-9. Unique Identifier : AIDSLINE MED/94296232; Molnar-Nadasdy G; Haesly I; Reed J; Altshuler G; Department of Pathology, University of Oklahoma Health Sciences; Center, Oklahoma City.; There are many pregnant mothers who have acquired immunodeficiency syndrome or who require immunosuppressive therapy for sundry reasons. Despite this, we have been able to find only one English-language report of placental cryptococcosis. We have had an opportunity to treat a pregnant mother who suffered from cryptoco
Cystic pulmonary lesions in Pneumocystis carinii infection.: Australas Radiol. 1994 May;38(2):138-40. Unique Identifier : AIDSLINE MED/94296332; Blackmore TK; Slavotinek JP; Gordon DL; Department of Microbiology and Infectious Diseases, Flinders; Medical Centre, Bedford Park, Australia.; Thick-walled pulmonary cavities are an uncommon manifestation of Pneumocystis carinii pneumonia (PCP). A case of PCP in a man with Acquired Immunodeficiency Syndrome (AIDS) presenting with a thick-walled pulmonary cavity and multiple smaller pulmonary air cysts is described. All of these lesions showed dramatic healin
Inhibition of 3'azido-3'deoxythymidine-resistant HIV-1 infection by dehydroepiandrosterone in vitro.: Biochem Biophys Res Commun. 1994 Jun 30;201(3):1424-32. Unique Identifier : AIDSLINE MED/94296419; Yang JY; Schwartz A; Henderson EE; Department of Microbiology and Immunology, Temple University; School of Medicine, Philadelphia 19140.; Human immunodeficiency virus type 1 (HIV-1) isolated from patients with acquired immunodeficiency syndrome (AIDS) shows resistance to 3 azido-3 deoxythymidine ( AZT ) after one or two years of treatment. AZT also has significant toxic side effects, furt
Oxidative stress and apoptosis in HIV infection: a role for plant-derived metabolites with synergistic antioxidant activity [see comments]: Immunol Today. 1994 May;15(5):209-13. Unique Identifier : AIDSLINE MED/94296538; Greenspan HC; Aruoma OI; LGD Biomedical Group, Annandale, NJ 08801.; The cascade of events resulting from oxidative stress is markedly similar to that which can initiate apoptosis, a possible mechanism of immune-cell loss in patients with HIV infection and AIDS. Since primary and secondary metabolites found in plants can act as synergistic antioxidants, and can prevent oxidation-indu
[Basic health care. AIDS and children]: TVZ. 1994 Feb 17;104(4):121-4. Unique Identifier : AIDSLINE MED/94296576; van de Pasch T
Phagemid pSIT permits efficient in vitro mutagenesis and tightly controlled expression in E. coli.: Biotechniques. 1994 Apr;16(4):626-8, 630-3. Unique Identifier : AIDSLINE GENBANK/U17139; Andreansky M; Hunter E; University of Alabama at Birmingham.; A new phagemid vector, pSIT, was constructed that allows both oligonucleotide-directed mutagenesis and tightly controlled, high-level expression of proteins in Escherichia coli. An efficient rate of mutagenesis is achieved by taking advantage of the double oligonucleotide primer technique. In addition to the mutagenic
'Needle-stick injuries and transmission of HIV to HCWs' [letter]: Br Dent J. 1994 May 7;176(9):331. Unique Identifier : AIDSLINE MED/94296751; Samaranayake L
[Take sides against injustice (interview by Siv Barstad)]: J Sykepleien. 1993 Nov 2;81(18):12-3. Unique Identifier : AIDSLINE MED/94296772; Aschjem O
[The extended hand (interview by Siv Barstad)]: J Sykepleien. 1993 Nov 2;81(18):23-4. Unique Identifier : AIDSLINE MED/94296778; Halvorsen E
Women's protective sexual behaviors: a test of the health belief model.: AIDS Educ Prev. 1994 Feb;6(1):1-11. Unique Identifier : AIDSLINE MED/94296834; Gielen AC; Faden RR; O'Campo P; Kass N; Anderson J; Johns Hopkins University School of Hygiene and Public Health,; Department of Health Policy and Management.; Heterosexual transmission of the human immunodeficiency virus (HIV) has become a significant health issue for women. The present study describes the extent to which a sample of women from an urban area report making efforts to protect themselves from becoming infected with HIV through several protective sexual behavio
Correlates of condom use among black, Hispanic, and white heterosexuals in San Francisco: the AMEN longitudinal survey. AIDS in Multi-Ethnic Neighborhoods survey.: AIDS Educ Prev. 1994 Feb;6(1):12-26. Unique Identifier : AIDSLINE MED/94296835; Catania JA; Coates TJ; Golden E; Dolcini MM; Peterson J; Kegeles S; Siegel D; Fullilove MT; Center for AIDS Prevention Studies, University of California, San; Francisco.; We examined correlates of condom use among heterosexual whites, blacks, and Hispanics (ages 20-45 years) with an human immunodeficiency virus (HIV) risk factor in a community-based longitudinal sample (San Francisco; n = 716). Lag models were used to examine hypothesized antecedents of condom use at wave 2. High level
Associations between condom experiences and beliefs, intentions, and use in a sample of urban, low-income, African-American and Hispanic youth.: AIDS Educ Prev. 1994 Feb;6(1):27-39. Unique Identifier : AIDSLINE MED/94296836; Norris AE; Ford K; School of Nursing, Boston College, Chestnut Hill, MA 02167.; This paper discusses negative experiences with using condoms reported by the condom user subsample of (n = 975) of a household probability sample of low income, urban, African-American and Hispanic youth. Condom users were asked about 12 specific experiences with condoms. Although the pattern of the association varied
Impact of culturally sensitive AIDS video education on the AIDS risk knowledge of African-American adolescents.: AIDS Educ Prev. 1994 Feb;6(1):40-52. Unique Identifier : AIDSLINE MED/94296837; Stevenson HC; Davis G; University of Pennsylvania, Graduate School of Education,; Philadelphia 19104-6216.; AIDS video education is a major mode of providing information about the spread and prevention of the human immunodeficiency virus (HIV). Very little has been written about the need for culturally salient messages in increasing the acquisition and retention of HIV/AIDS prevention information, even though there is consi
Worksite AIDS education: a case study of the New York City police.: AIDS Educ Prev. 1994 Feb;6(1):53-64. Unique Identifier : AIDSLINE MED/94296838; Barr JK; Warshaw LJ; New York Business Group on Health, Inc., NY 10017-6752.; The New York City Police Department (NYCPD) offers AIDS education on a continuing basis to all uniformed police personnel. The program consists of a videotape, published materials, lecture with medical experts, and individual counseling available on request. This study focuses on police officers sources of informatio
Brokering: a process for establishing long-term and stable links with gay male communities for research and public health education.: AIDS Educ Prev. 1994 Feb;6(1):65-73. Unique Identifier : AIDSLINE MED/94296839; Silvestre AJ; Department of Infectious Diseases and Microbiology, Graduate; School of Public Health, University of Pittsburgh, PA.; The success of efforts to prevent continued transmission of the human immunodeficiency virus (HIV) and to increase compliance with HIV prophylactic interventions among homosexual and bisexual men will depend in part on health care professionals understanding of and ability to establish linkages with these men. In ord
Immigration and HIV infection: a pilot study.: AIDS Educ Prev. 1994 Feb;6(1):74-80. Unique Identifier : AIDSLINE MED/94296840; Loue S; Oppenheim S; Department of Epidemiology, School of Public Health, University; of California at Los Angeles.; This pilot study was conducted to determine areas in which additional education regarding the human immunodeficiency virus (HIV) is needed by the undocumented and recently immigrated HIV-infected population, and to obtain preliminary information on the ability of this community to access medical treatment for HIV. Inf
Understanding cultural obstacles to HIV/AIDS prevention in Africa.: AIDS Educ Prev. 1994 Feb;6(1):81-9. Unique Identifier : AIDSLINE MED/94296841; Scott SJ; Mercer MA; Johns Hopkins University, School of Hygiene and Public Health,; Institute for International Programs, Baltimore, MD 21202.; Global efforts to prevent further spread of the human immunodeficiency virus (HIV) are faced with tremendous obstacles, and limited understanding of the cultural and social context of HIV and AIDS is an important factor hindering prevention efforts to date. Examples from the authors experience in providing technical
AIDS leading cause of death in men 25 to 44 [news]: Oncology (Huntingt). 1994 May;8(5):94. Unique Identifier : AIDSLINE MED/94296906
[Apoptosis and diseases]: Hum Cell. 1994 Mar;7(1):27-32. Unique Identifier : AIDSLINE MED/94296918; Onishi Y; Kizaki H; Department of Biochemistry, Tokyo Dental College, Chiba, Japan.; Apoptosis, a form of cell death defined by morphological and biochemical characteristics, is involved in many important physiological phenomena including embryogenesis, organ involution, maintenance of homeostasis and biodefense systems of the body. Impaired regulation of apoptosis may play a part in the etiology of m
Advantages and limitations of hemodilution.: Semin Thorac Cardiovasc Surg. 1994 Apr;6(2):87-97. Unique Identifier : AIDSLINE MED/94297056; Estafanous FG; Mekhail N; Yared JP; Department of General Anesthesiology, Cleveland Clinic; Foundation, OH 44195.
[Legionella pneumophila pneumonia in a patient with human immunodeficiency virus infection. An autopsy diagnosis (letter)]: An Med Interna. 1994 Jan;11(1):47-8. Unique Identifier : AIDSLINE MED/94297123; Almirante Gragera B; Tarragona Foradada J; Ferrer Marcelles A; Garcia Jimenez A
Rearrangements of the BCL-6 gene in acquired immunodeficiency syndrome-associated non-Hodgkin's lymphoma: association with diffuse large-cell subtype.: Blood. 1994 Jul 15;84(2):397-402. Unique Identifier : AIDSLINE MED/94297207; Gaidano G; Lo Coco F; Ye BH; Shibata D; Levine AM; Knowles DM; Dalla-Favera R; Department of Pathology, College of Physicians and Surgeons,; Columbia University, New York, NY 10032.; Acquired immunodeficiency syndrome (AIDS)-associated non-Hodgkin s lymphomas (AIDS-NHL), a major source of morbidity and mortality among AIDS patients, are derived from B cells and can be classified into two main histologic categories, small noncleaved cell lymphoma (SNCCL) and diffuse large-cell lymphoma (DLCL). DLCL
Tumor necrosis factor-alpha downregulates protein S secretion in human microvascular and umbilical vein endothelial cells but not in the HepG-2 hepatoma cell line.: Blood. 1994 Jul 15;84(2):483-9. Unique Identifier : AIDSLINE MED/94297219; Hooper WC; Phillips DJ; Ribeiro MJ; Benson JM; George VG; Ades EW; Evatt BL; Hematologic Diseases Branch, Centers for Disease Control and; Prevention, Altanta, GA 30333.; Protein S deficiency, which is associated with thrombosis, can either be inherited or acquired. Recently, we reported that a decrease in free protein S was observed in 19 of 25 persons with HIV/AIDS. The proinflammatory cytokine, tumor necrosis factor-alpha (TNF-alpha), has been reported to be elevated in human immuno
Solvent/detergent-treated plasma suppresses shear-induced platelet aggregation and prevents episodes of thrombotic thrombocytopenic purpura.: Blood. 1994 Jul 15;84(2):490-7. Unique Identifier : AIDSLINE MED/94297220; Moake J; Chintagumpala M; Turner N; McPherson P; Nolasco L; Steuber C; Santiago-Borrero P; Horowitz M; Pehta J; Baylor College of Medicine, Houston, TX.; Two children with congenital chronic relapsing thrombotic thrombocytopenic purpura (TTP) have episodes every 3 weeks. These relapses can be prevented by the infusion of normal fresh-frozen plasma (FFP) without concurrent plasmapheresis. We conducted a study to determine whether the exposure of normal plasma to agents
HIV infection in inner city A & E department [letter; comment]: BMJ. 1994 Jun 18;308(6944):1637. Unique Identifier : AIDSLINE MED/94297427; Barton SE; Booth SJ
Zidovudine could stop HIV infection of babies [news]: BMJ. 1994 Jun 25;308(6945):1661. Unique Identifier : AIDSLINE MED/94297445; Dyer O
The 1993 Okey Memorial Lecture. Cross-national studies of AIDS among injecting drug users.: Addiction. 1994 Apr;89(4):383-92. Unique Identifier : AIDSLINE MED/94297490; Des Jarlais DC; Beth Israel Medical Center, New York, NY 10003.; HIV infection among injecting drug users has become a world-wide public health problem. This raises fundamental questions about the modifiability of drug-using behavior and of the influence of different national settings upon the modification of drug use behavior. Data from the World Healt
Explanations for sharing injection equipment in injecting drug users and barriers to safer drug use.: Addiction. 1994 Apr;89(4):473-9. Unique Identifier : AIDSLINE MED/94297506; Ross MW; Wodak A; Stowe A; Gold J; Center for Health Promotion Research and Development, University; of Texas, Houston 77225.; We examined the explanations given by a sample of 1245 injecting drug users in Sydney, Australia for accepting used injection equipment. Factor analysis of these reasons revealed three dimensions of sharing: not caring when withdrawing or intoxicated, unavailability of equipment
Infection control in NSW HIV case [letter]: Aust Nurs J. 1994 Apr;1(9):6. Unique Identifier : AIDSLINE MED/94297687; Young J
Anatomical distribution of HTLV-I proviral sequence in an autopsy case of HTLV-I associated myelopathy: a polymerase chain reaction study.: Pathol Int. 1994 Jan;44(1):27-33. Unique Identifier : AIDSLINE MED/94297691; Sueyoshi K; Goto M; Johnosono M; Sato E; Shibata D; Second Department of Pathology, Faculty of Medicine, Kagoshima; University, Japan.; HTLV-I associated myelopathy (HAM) is a slowly progressive paraplegia of the lower extremities observed among HTLV-I carriers. An autopsy of a typical HAM case in which perivascular lymphocytic infiltration was not limited to the central nervous system was examined. Spinal dorsal roots, salivary gland, lungs, liver an
Aberrant expression of the monocyte/macrophage phenotype in a human T cell line immortalized by HTLV-I and an adult T cell leukemia/lymphoma cell line.: Pathol Int. 1994 Jan;44(1):39-48. Unique Identifier : AIDSLINE MED/94297693; Jeon HJ; Akagi T; Yoshino T; Takahashi K; Hayashi K; Kondo E; Sarker AB; Teramoto N; Fujiwara K; Ohara N; et al; Second Department of Pathology, Okayama University Medical; School, Japan.; An HTLV-I-immortalized human T cell line (JP-2), a N-methyl-N -nitro-N-nitrosoguanidine-treated JP-2 line (JP-2T), and an adult T cell leukemia cell line (ATL-1T) were examined morphologically and phenotypically. All of these cell lines expressed some T cell markers, including CD4, and showed rearrangement of T cell r
Genotype and phenotype of oral Candida albicans from patients infected with the human immunodeficiency virus.: Microbiology. 1994 May;140 ( Pt 5):1195-202. Unique Identifier : AIDSLINE MED/94297742; McCullough MJ; Ross BC; Dwyer BD; Reade PC; School of Dental Science, Faculty of Medicine, Dentistry and; Health Sciences, University of Melbourne, Australia.; Candida albicans has been shown to vary in its phenotypic expression with the progression of human immunodeficiency virus (HIV) infection. Isolates of C. albicans were obtained from 45 patients with HIV infection during the progression of their disease and differentiated using two methods. The first utilized the morph
Measurement of the serum tumor marker neuron-specific enolase in patients with benign pulmonary diseases.: Am J Respir Crit Care Med. 1994 Jul;150(1):143-5. Unique Identifier : AIDSLINE MED/94297830; Collazos J; Esteban C; Fernandez A; Genolla J; Section of Internal Medicine, Hospital de Galdakao, Vizcaya,; Spain.; Serum concentrations of neuron-specific enolase (NSE) were measured in 135 patients with benign pulmonary diseases who also underwent a clinical, laboratory, and radiologic evaluation. Eleven percent of the patients as a whole and 27.3% of those who were tuberculous had abnormal serum levels of NSE. Significant differ
Pulmonary hypertension in a murine model of the acquired immunodeficiency syndrome.: Am J Respir Crit Care Med. 1994 Jul;150(1):194-9. Unique Identifier : AIDSLINE MED/94297839; Gillespie MN; Hartsfield CL; O'Connor WN; Cohen DA; Division of Pharmacology and Experimental Therapeutics, College; of Pharmacy, Lexington, Kentucky.; Rapidly accumulating evidence suggests that a proportion of patients with acquired immunodeficiency syndrome (AIDS) develop hypertensive pulmonary vascular disease reminiscent of primary pulmonary hypertension. As an initial step to explore the link between AIDS and hypertensive pulmonary vascular disease, the present
[An evaluation of the blood culture in disseminated mycobacteriosis]: Arch Bronconeumol. 1994 Apr;30(4):181-4. Unique Identifier : AIDSLINE MED/94297886; Nogales MC; Aretio R; Beiztegui A; Munoz F; Martin E; Servicio de Microbiologia, Hospital Universitario de Valme,; Sevilla.; The objective of this study was to evaluate the usefulness of blood culture in the diagnosis of disseminated mycobacteria (DMB). This prospective study included all blood cultures done for patients with fever and under suspicion of having DMB between January 1991 and July 1992. Fifty-seven blood samples from 16 patien
[Neutrophilia in the bronchoalveolar lavage of patients with AIDS and Pneumocystis carinii pneumonia. Reflections on its prognostic value in the Spanish setting]: Arch Bronconeumol. 1994 Apr;30(4):192-5. Unique Identifier : AIDSLINE MED/94297889; Sauleda J; Gea J; Aran X; Gimferrer E; Conangla M; Broquetas JM; Servicio de Neumologia, Hospital del Mar, Barcelona.; The prognostic value of neutrophilia (> 5%) in bronchoalveolar lavage (BAL) in our context is studied in 21 patients with AIDS and Pneumocystis carinii pneumonia. Neutrophilia does not seem to be a good prognostic indicator in our context. We have found this condition, with a mean of 6 +/- 4%, in only 33% of our sampl
[3 nonidiopathic forms of bronchiolitis obliterans organizing pneumonia]: Arch Bronconeumol. 1994 May;30(5):263-5. Unique Identifier : AIDSLINE MED/94297907; Garcia Rio F; Garcia Satue JL; Prados C; Casadevall J; Gomez L; Pino JM; Servicio de Neumologia, Hospital La Paz, Facultad de Medicina,; Universidad Autonoma, Madrid.; Bronchiolitis obliterans organizing pneumonia is the most serious disease of the bronchioli. An idiopathic form of the disease important for differential diagnosis in incipient forms of pulmonary fibrosis has been reported in the literature, along with other forms associated to drug use, infections, and collagen and l
The development of a vaccine against feline immunodeficiency virus [see comments]: Br Vet J. 1994 Jan-Feb;150(1):25-39. Unique Identifier : AIDSLINE MED/94297954; Hosie MJ; Department of Veterinary Pathology, University of Glasgow; Veterinary School, Bearsden.; Feline immunodeficiency virus (FIV) is a retrovirus causing significant disease in cats. The virus has been shown to be similar biologically to the human immunodeficiency virus (HIV), the cause of acquired immunodeficiency syndrome (AIDS) in humans. Much interest has been expressed in the use of FIV as an animal model
FIV and HIV vaccines--problems and prospects [editorial; comment]: Br Vet J. 1994 Jan-Feb;150(1):7-8. Unique Identifier : AIDSLINE MED/94297959; Harbour DA
Clinical practice guidelines for HIV infection: progress towards making AIDS a primary care disease [editorial]: Cleve Clin J Med. 1994 May-Jun;61(3):238-9. Unique Identifier : AIDSLINE MED/94298228; Goldfarb J; Longworth DL
Cultural studies on two isolates of Mycobacterium genavense from patients with acquired immunodeficiency syndrome.: Diagn Microbiol Infect Dis. 1994 Jan;18(1):7-12. Unique Identifier : AIDSLINE MED/94298326; Tortoli E; Simonetti MT; Dionisio D; Meli M; Laboratory for Microbiology and Virology, Careggi Hospital,; Florence, Italy.; Two strains of the newly proposed species Mycobacterium genavense have been isolated, using the radiometric system (Bactec, Becton Dickinson), from the blood of two HIV-infected patients. Disseminated infections due to the new organism closely resemble those of the Mycobacterium avium complex, with prevalently intesti
Detection of intracellular HIV in lymphocytes by flow cytometry.: Cytometry. 1994 Apr 1;15(4):359-70. Unique Identifier : AIDSLINE MED/94298408; Gadol N; Crutcher GJ; Busch MP; Irwin Memorial Blood Centers, San Francisco, California; 94118-0318.; Various permeabilization procedures and defined gating techniques were tested in order to optimize existing flow cytometric assays and devise a specific assay for the direct detection of intracellular HIV-1 antigens in clinical blood specimens. In our optimal procedure, blood lysed with Orthomune Lysing Reagent was fi
Hyperosmolar nonketotic diabetic syndrome following treatment of human immunodeficiency virus infection with didanosine.: Diabetes Care. 1994 Apr;17(4):316-7. Unique Identifier : AIDSLINE MED/94298478; Munshi MN; Martin RE; Fonseca VA; Department of Medicine, University of Arkansas for Medical; Sciences, Little Rock.; OBJECTIVE--To determine whether didanosine (DDI), one of the drugs commonly used to treat infection with human immunodeficiency virus (HIV), contributes to the development of diabetes and hyperosmolar nonketotic diabetic syndrome (HNKDS). CASE SUMMARY--One female patient was treated with DDI for infection with HIV dur
Injecting behaviour and risky needle use amongst methadone maintenance clients.: Drug Alcohol Depend. 1994 Jan;34(2):113-9. Unique Identifier : AIDSLINE MED/94298488; White JM; Dyer KR; Ali RL; Gaughwin MD; Cormack S; Drug and Alcohol Services Council, Parkside, Australia.; The injecting behaviour and risky needle use of a sample of 193 methadone maintenance clients was investigated. The majority of the sample (n = 116) reported injecting one or more drugs in the month prior to data collection. Compared with non-injectors, the injectors were slightly younger, had been on the methadone pr
The relationships of HIV status and HIV risky behavior with readiness for treatment.: Drug Alcohol Depend. 1994 Jan;34(2):129-38. Unique Identifier : AIDSLINE MED/94298490; McCusker J; Bigelow C; Frost R; Hindin R; Vickers-Lahti M; Zorn M; University of Massachusetts AIDS Research Unit, School of Public; Health, Amherst 01003.; We investigated the associations of self-reported HIV status and risky injection practices with dependent variables measuring readiness and motivation for treatment and depression among 550 clients at two residential drug abuse treatment programs. The results suggest that a positive HIV status may be associated with m
Drug use and HIV risk-taking behaviour among injecting drug users not currently in treatment in Sydney, Australia.: Drug Alcohol Depend. 1994 Jan;34(2):155-60. Unique Identifier : AIDSLINE MED/94298493; Baker A; Kochan N; Dixon J; Wodak A; Heather N; National Drug and Alcohol Research Centre, University of New; South Wales, Kensington, Sydney, Australia.; This study investigated the drug use patterns and HIV risk-taking behaviour of 200 injecting drug users (IDU) not currently in treatment in Sydney, Australia . Although there was low HIV seroprevalence, unsafe injecting and sexual practices were common. Variables that were predic
Hopelessness in i.v. drug users not in treatment and seeking HIV testing and counselling.: Drug Alcohol Depend. 1994 Jan;34(2):99-103. Unique Identifier : AIDSLINE MED/94298496; Steer RA; Iguchi MY; Platt JJ; Department of Psychiatry, University of Medicine and Dentistry of; New Jersey, School of Osteopathic Medicine, Camden.; The Beck Hopelessness Scale (BHS) was administered to 2379 intravenous drug users who were not in treatment, unaware of their human-immunodeficiency-virus (HIV) status and seeking HIV testing and counselling. Three BHS principal components were identified reflecting resignation to the futility of changing the future,
[Idiopathic CD4 lymphocytopenia with lethal Salmonella typhimurium sepsis]: Dtsch Med Wochenschr. 1994 Jul 8;119(27):956-8. Unique Identifier : AIDSLINE MED/94298500; Burg S; Weber W; Kucherer C; I. Medizinische Abteilung, Krankenhaus der Barmherzigen Bruder,; Trier.; In April 1991, a then 43-year-old woman fell ill with a systemic cryptococcal infection which responded well to antimycotic treatment. Four months later she was found to have a T-helper cell deficiency (48/microliters, 15%). Since August 1992 she noted an increased tendency towards infections and had recurrent fever b
Human immunodeficiency viruses regulated by alternative trans-activators: genetic evidence for a novel non-transcriptional function of Tat in virion infectivity.: EMBO J. 1994 Jun 15;13(12):2886-96. Unique Identifier : AIDSLINE MED/94298780; Huang LM; Joshi A; Willey R; Orenstein J; Jeang KT; Molecular Virology Section, National Institute of Allergy and; Infectious Diseases, Bethesda, MD 20892.; Thirteen genetically altered HIV-1 proviruses were created. These various genomes can be segregated into three groups: (i) a set of tat(-) viruses that have a functional HTLV-I Tax inserted in nef; (ii) a set of tat(-) viruses with Gal4 binding sites inserted in U3 and a Gal4-VP16 cDNA inserted in nef; and (iii) a set
Facilitation of hammerhead ribozyme catalysis by the nucleocapsid protein of HIV-1 and the heterogeneous nuclear ribonucleoprotein A1.: EMBO J. 1994 Jun 15;13(12):2904-12. Unique Identifier : AIDSLINE MED/94298782; Bertrand EL; Rossi JJ; Beckman Research Institute of the City of Hope, Department of; Molecular Genetics, Duarte, CA 91010.; In order to improve the activity of hammerhead ribozymes in vivo, we have analyzed the effect of several prototypical RNA binding proteins on the ribozyme cleavage reaction: bacteriophage T4 gene 32 protein (gp32), hnRNP A1 (A1) and the nucleocapsid protein of HIV-1 (NCp7). We show that, while gp32 has no effect on th
An RNA chaperone activity of non-specific RNA binding proteins in hammerhead ribozyme catalysis [published erratum appears in EMBO J 1994 Aug 15;13(16):3926]: EMBO J. 1994 Jun 15;13(12):2913-24. Unique Identifier : AIDSLINE MED/94298783; Herschlag D; Khosla M; Tsuchihashi Z; Karpel RL; Department of Biochemistry, Hughes Medical Institute, Stanford; University, CA 94305-5307.; We have previously shown that a protein derived from the p7 nucleocapsid (NC) protein of HIV type-1 increases kcat/Km and kcat for cleavage of a cognate substrate by a hammerhead ribozyme. Here we show directly that the increase in kcat/Km arises from catalysis of the annealing of the RNA substrate to the ribozyme and
Mosaic genome structure of simian immunodeficiency virus from west African green monkeys.: EMBO J. 1994 Jun 15;13(12):2935-47. Unique Identifier : AIDSLINE GENBANK/U04018; Jin MJ; Hui H; Robertson DL; Muller MC; Barre-Sinoussi F; Hirsch VM; Allan JS; Shaw GM; Sharp PM; Hahn BH; Department of Medicine, University of Alabama at Birmingham; 35294.; Elucidation of the phylogenetic origins of simian and human immunodeficiency viruses (SIV and HIV) is fundamental to the understanding of HIV pathogenesis and the spread of AIDS worldwide. In this study, we molecularly characterized multiple SIVAGM isolates from four different African green monkey species (vervet, gri
[Primary and secondary immunodeficiency states]: Gematol Transfuziol. 1993 Apr;38(4):37-41. Unique Identifier : AIDSLINE MED/94299071; Nefedova VE
[The role of disinfection and sterilization in the prevention of HIV infection in therapeutic and preventive medical facilities]: Gig Sanit. 1993 Sep;(9):47-50. Unique Identifier : AIDSLINE MED/94299193; Shandala MG; Panteleeva LG; Ramkova NV
The pathological manifestations of pulmonary toxoplasmosis in the acquired immunodeficiency syndrome.: Hum Pathol. 1994 Jul;25(7):652-8. Unique Identifier : AIDSLINE MED/94299242; Nash G; Kerschmann RL; Herndier B; Dubey JP; Department of Pathology, Baystate Medical Center/Tufts University; School of Medicine, Springfield, MA 01199.; Pulmonary toxoplasmosis, once considered a rare complication of human immunodeficiency virus infection, recently has been reported with increasing frequency in patients with the acquired immunodeficiency syndrome (AIDS). However, published descriptions of the pathologic changes have been scanty, involve mainly single
HIV guidebook for clinicians available [news]: J Am Osteopath Assoc. 1994 Apr;94(4):288, 290. Unique Identifier : AIDSLINE MED/94299442
Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein.: J Biol Chem. 1994 Jul 8;269(27):17757-60. Unique Identifier : AIDSLINE GENBANK/U10279; Huang QQ; Yao SY; Ritzel MW; Paterson AR; Cass CE; Young JD; Department of Physiology, University of Alberta, Edmonton,; Canada.; Expression screening in Xenopus oocytes was used to isolate a cDNA from rat jejunal epithelium encoding a Na(+)-dependent nucleoside transport protein (named cNT1). The cDNA sequence of cNT1 predicts a protein of 648 amino acids (relative molecular mass 71,000) with 14 potential transmembrane domains. Data base search
Effects of gamma irradiation on the human immunodeficiency virus. A study in frozen human bone-patellar ligament-bone grafts obtained from infected cadavera.: J Bone Joint Surg Am. 1994 Jul;76(7):1032-5. Unique Identifier : AIDSLINE MED/94299571; Fideler BM; Vangsness CT Jr; Moore T; Li Z; Rasheed S; Department of Orthopaedic Surgery, University of Southern; California School of Medicine, Los Angeles 90033.; We studied the effects of several different doses of gamma radiation, ranging from 20,000 to 40,000 gray (2.0 to 4.0 megarad), with respect to the inactivation of the human immunodeficiency virus in fresh-frozen, whole bone-patellar ligament-bone grafts. Although the International Atomic Energy Agency has recommended
Retroviral transmission by the transplantation of connective-tissue allografts. An experimental study.: J Bone Joint Surg Am. 1994 Jul;76(7):1036-41. Unique Identifier : AIDSLINE MED/94299572; Nemzek JA; Arnoczky SP; Swenson CL; Laboratory for Comparative Orthopaedic Research, College of; Veterinary Medicine, Michigan State University, East Lansing; 48824-1314.; The transmission of a retrovirus by the transplantation of allografts of connective tissues was studied in a feline model with use of the feline leukemia virus, a retrovirus with a replication cycle and pathological characteristics similar to those of the human immunodeficiency virus. The retrovirus was used to infect
Antibiotic susceptibilities of AIDS-associated mycoplasmas.: J Clin Microbiol. 1994 Apr;32(4):1101-3. Unique Identifier : AIDSLINE MED/94299800; Poulin SA; Perkins RE; Kundsin RB; Brigham and Women's Hospital, Harvard Medical School, Boston,; Massachusetts 02115.; Because mycoplasmas may be a cofactor in the progression of human immunodeficiency virus infection to AIDS, their susceptibilities to antibiotics need to be known in the event that appropriate therapy is required. The mycoplasmas studied were a stock culture strain of Mycoplasma fermentans, two strains of M. fermentan
Fluconazole-resistant recurrent oral candidiasis in human immunodeficiency virus-positive patients: persistence of Candida albicans strains with the same genotype.: J Clin Microbiol. 1994 Apr;32(4):1115-8. Unique Identifier : AIDSLINE MED/94299805; Millon L; Manteaux A; Reboux G; Drobacheff C; Monod M; Barale T; Michel-Briand Y; Laboratorie de Bacteriologie et Parasitologie, Faculte de; Medecine, Hopital Jean Minjoz, Besancon, France.; Thirty human immunodeficiency virus-positive patients carrying Candida albicans in their oropharynx were treated with fluconazole and were monitored for 90 to 570 days. Fluconazole-resistant C. albicans (MIC, > 32 micrograms/ml) appeared only in seven patients and only after 90 days of treatment corresponding to a tot
CD4+ lymphocytopenia due to common variable immunodeficiency mimicking AIDS.: J Clin Pathol. 1994 Apr;47(4):364-6. Unique Identifier : AIDSLINE MED/94299863; Kaczmarski RS; Webster AD; Moxham J; Davison F; Sutherland S; Mufti GJ; Department of Haematological Medicine, King's College School of; Medicine and Dentistry, London.; There are an increasing number of published reports of patients with acquired immunodeficiency without evidence of HIV infection, who have been labelled as having idiopathic CD4+ lymphocytopenia. The case is reported here of a young man who presented with Pneumocystis carinii pneumonia (PCP), CD4+ lymphopenia, and hyp
Follicular dendritic cells retain HIV-1 particles on their plasma membrane, but are not productively infected in asymptomatic patients with follicular hyperplasia.: J Immunol. 1994 Aug 1;153(3):1352-9. Unique Identifier : AIDSLINE MED/94300098; Schmitz J; van Lunzen J; Tenner-Racz K; Grossschupff G; Racz P; Schmitz H; Dietrich M; Hufert FT; Clinical Medicine Section, Bernhard Nocht Institute for Tropical; Medicine, Hamburg, Germany.; During HIV-1 infection, extensive alterations can be observed in the germinal centers (GCs) of lymphatic tissue. The initial hyperplasia of GCs is followed by disintegration and involution of these structures. The process is accompanied by progressive destruction of the network of follicular dendritic cells (FDCs). We
Generation of antigen-specific CD8+ CTLs from naive precursors.: J Immunol. 1994 Aug 1;153(3):996-1003. Unique Identifier : AIDSLINE MED/94300111; Mehta-Damani A; Markowicz S; Engleman EG; Department of Pathology, Stanford University School of Medicine,; CA 94305.; Class I MHC-restricted CTLs are an important component of the host immune response against viral infections, and CTL effectors can often be isolated from infected individuals. However, the mechanism responsible for the induction of CTLs is incompletely understood because, in part, of the difficulty in generating such
Deleted HTLV retrovirus may be involved in the development of cutaneous T-cell lymphomas [letter; comment]: J Invest Dermatol. 1994 Jul;103(1):134. Unique Identifier : AIDSLINE MED/94300119; D'Ican M; Souteyrand P; Gasmi M; Desgranges C
Interferon-alpha generation in mice responding to challenge with UV-inactivated herpes simplex virus.: J Interferon Res. 1994 Feb;14(1):17-24. Unique Identifier : AIDSLINE MED/94300139; Bhuiya TA; Shodell M; Fitzgerald-Bocarsly PA; Murasko D; Shah K; Drake D; Siegal FP; Long Island Jewish Medical Center, Albert Einstein College of; Medicine, New Hyde Park, NY 11042.; In humans with advanced human immunodeficiency virus (HIV) infection, an interferon-alpha (IFN-alpha) response by a specialized blood mononuclear cell to herpes simplex virus (HSV) in vitro is associated with resistance to opportunistic infections. A cell type of unknown lineage, designated the natural IFN-producing c
[Sexually transmitted disease infection in HIV carriers]: Kansenshogaku Zasshi. 1994 Apr;68(4):474-8. Unique Identifier : AIDSLINE MED/94300144; Ishikawa K; Takebe Y; Kishimoto R; Kurata T; Kawana T; Yamanashi Institute for Public Health.; Heterosexual transmission of the human immunodeficiency virus (HIV) appears to occur readily all over the world. Recent reports have suggested an association between HIV and sexually transmitted disease (STD). We conducted a case study among foreign female prostitutes who were seropositive to HIV to determine the prev
LPS-inducible nuclear factor in human monocytes that binds the negative regulatory element of the HIV LTR.: J Leukoc Biol. 1994 Jul;56(1):21-6. Unique Identifier : AIDSLINE MED/94300220; Musso T; Bosco MC; Longo DL; Espinoza-Delgado I; Sica A; Cox GW; Gusella GL; Forni G; Varesio L; Biological Carcinogenesis and Development Program, PRI/DynCorp,; Turin, Italy.; We studied the constitutive and lipopolysaccharide (LPS)-induced expression of nuclear protein binding to the negative regulatory element (NRE) of the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) in fresh human monocytes. We demonstrated the existence of a constitutive factor binding to the N
Family physician management of HIV and AIDS: a Vermont study.: J Fam Pract. 1994 Jul;39(1):50-4. Unique Identifier : AIDSLINE MED/94300297; Gleeson CJ; Havron A; Wadland WC; Department of Family Practice, University of Vermont, Burlington; 05486.; BACKGROUND. The purpose of this study was to survey family physicians regarding the barriers to providing primary care for persons with human immunodeficiency virus (HIV) infections and acquired immunodeficiency syndrome (AIDS) in a small, rural state with a low incidence of infection. The study focused on issues faci
Implications of the Occupational Safety and Health Administration's bloodborne pathogen standard for the occupational health professional.: J Occup Med. 1994 May;36(5):548-55. Unique Identifier : AIDSLINE MED/94300460; Udasin IG; Gochfeld M; UMDNJ-Robert Wood Johnson Medical School, Department of; Environmental and Community Medicine, Piscataway.; On December 6, 1991. The Occupational Health and Safety Administration (OSHA) issued its final regulation concerning occupational exposure to bloodborne pathogens (29 CFR 1910.1030). OSHA has determined that workers in a variety of settings face a significant health risk as the result of occupational exposure to blood
Drug treatment on demand--not.: J Psychoactive Drugs. 1994 Jan-Mar;26(1):1-11. Unique Identifier : AIDSLINE MED/94300482; Wenger LD; Rosenbaum M; Institute for Scientific Analysis, San Francisco, California; 94110.; Drug treatment on demand, appropriate and affordable drug treatment for injection drug users who are ready to enter a program, is a humane approach to drug treatment services and an important mechanism to halt the spread of HIV. However, drug treatment on demand is not a reality in the Uni
Sexual sensation seeking: scale development and predicting AIDS-risk behavior among homosexually active men.: J Pers Assess. 1994 Jun;62(3):385-97. Unique Identifier : AIDSLINE MED/94300493; Kalichman SC; Johnson JR; Adair V; Rompa D; Multhauf K; Kelly JA; Center for AIDS Intervention Research, Medical College of; Wisconsin.; Sensation seeking, the propensity to prefer exciting, optimal, and novel stimulation or arousal, is a potential mediating factor in sexual risk for human immunodeficiency virus infection (HIV), the cause of acquired immunodeficiency syndrome (AIDS). However, the most widely used measure of sensation seeking, the Sensa
From the Food and Drug Administration.: JAMA. 1994 Aug 3;272(5):344. Unique Identifier : AIDSLINE MED/94300768; Nightingale SL
[Peripheral T cell lymphoma (immunoblastic type, HTLV-1 negative) associated with aganglionosis of the intestine]: Rinsho Ketsueki. 1994 May;35(5):495-500. Unique Identifier : AIDSLINE MED/94300824; Kondo H; Harigaya K; Kurosu K; Yumoto N; Mikata A; Department of Medicine, Shimizu Kousei Hospital.; A 56-year-old female was hospitalized in 1992, because of fever and lymphadenopathy. She had ileus due to aganglionosis of the intestine diagnosed in 1990. Blood tests disclosed anemia and thrombocytopenia. Peripheral blood smear demonstrated 69.5% abnormal cells and a T-cell origin was demonstrated on cell marker stu
The Virus Cancer Program of the 1970s: a personal and retrospective view.: Lab Anim Sci. 1994 Apr;44(2):101-13. Unique Identifier : AIDSLINE MED/94300901; Gardner MB; Department of Pathology, School of Medicine, University of; California, Davis 95616.
A Perceived Health Index for use in persons with advanced HIV disease: derivation, reliability, and validity.: Med Care. 1994 Jul;32(7):716-31. Unique Identifier : AIDSLINE MED/94301048; Bozzette SA; Hays RD; Berry SH; Kanouse DE; Department of Medicine, University of California San Diego School; of Medicine.; Acceptance of health status as an outcome in clinical trials of new treatments for HIV disease has been hampered by the lack of valid and clinically relevant means of summarizing differences across multiple dimensions. We formed a summary Perceived Health Index from health status measures adapted from RAND Medical Out
[HIV infection and risk behavior among drug users served by a program of syringe exchange (letter)]: Med Clin (Barc). 1994 May 14;102(18):719. Unique Identifier : AIDSLINE MED/94301073; Bravo MJ; Colomo C; Barrio G; de la Fuente L
Minireview: trichosanthin--a protein with multiple pharmacological properties.: Life Sci. 1994;55(4):253-62. Unique Identifier : AIDSLINE MED/94301141; Shaw PC; Chan WL; Yeung HW; Ng TB; Department of Biochemistry, Chinese University of Hong Kong,; Shatin, NT.; Trichosanthin (TCS), a protein isolated from the root tuber of the Chinese medicinal herb Trichosanthes kirilowii Maxim., is used to induce abortion in China . It also possesses immunomodulatory, anti-tumor and anti-human immunodeficiency virus properties. TCS is a member of the fami
Telephone conference call on pediatric HIV [news]: MCN Am J Matern Child Nurs. 1994 May-Jun;19(3):178. Unique Identifier : AIDSLINE MED/94301159
Michael Boucree, MD. Looking AIDS in the eye.: Mich Med. 1994 May;93(5):25-6. Unique Identifier : AIDSLINE MED/94301234; Ward RD
[Parasitic diseases of the lungs]: Med Parazitol (Mosk). 1993 Mar-Apr;(2):43-50. Unique Identifier : AIDSLINE MED/94301282; Lavdovskaia MV
A longitudinal study of human immunodeficiency virus transmission by heterosexual partners. European Study Group on Heterosexual Transmission of HIV [see comments]: N Engl J Med. 1994 Aug 11;331(6):341-6. Unique Identifier : AIDSLINE MED/94301345; de Vincenzi I; European Centre for the Epidemiological Monitoring of AIDS,; Hopital National de Saint-Maurice, France.; BACKGROUND. Worldwide, the predominant mode of human immunodeficiency virus (HIV) transmission is heterosexual intercourse, but the risk of heterosexual transmission and the effectiveness of measures to prevent it are not well defined. METHODS. We conducted a prospective study of HIV-negative subjects whose only risk
Condoms and HIV transmission [editorial; comment]: N Engl J Med. 1994 Aug 11;331(6):391-2. Unique Identifier : AIDSLINE MED/94301353; Johnson AM
Short-term, combined use of paracetamol and zidovudine does not alter the pharmacokinetics of either drug.: Neth J Med. 1994 May;44(5):161-5. Unique Identifier : AIDSLINE MED/94301428; Burger DM; Meenhorst PL; Underberg WJ; van der Heijde JF; Koks CH; Beijnen JH; Department of Pharmacy, Slotervaart Hospital, Amsterdam,; Netherlands.; OBJECTIVE: To investigate a possible pharmacokinetic interaction between zidovudine and paracetamol. METHODS: Six patients with AIDS took both zidovudine ( AZT ; 1000-1200 mg/day) and paracetamol (500 mg every 6 h) for 7 days. Pharmacokinetic monitoring
AIDS update [news]: N J Med. 1994 May;91(5):295. Unique Identifier : AIDSLINE MED/94301573
New research approach could revolutionise AIDS prevention [news]: Occup Health (Lond). 1994 Jan;46(1):2. Unique Identifier : AIDSLINE MED/94301596
AIDS update. New UN programme [news]: Occup Health (Lond). 1994 Mar;46(3):77. Unique Identifier : AIDSLINE MED/94301600
AIDS update. Pharmaceutical companies work with WHO [news]: Occup Health (Lond). 1994 Apr;46(4):113. Unique Identifier : AIDSLINE MED/94301606
Advice for business travel: the wider picture.: Occup Health (Lond). 1994 Jun;46(6):200-3. Unique Identifier : AIDSLINE MED/94301619; Goodwin K; Brennan D
Actinomycosis of the nasal septum in a patient infected with the human immunodeficiency virus.: Otolaryngol Head Neck Surg. 1994 Jul;111(1):130-3. Unique Identifier : AIDSLINE MED/94301691; Kingdom TT; Tami TA; Department of Otolaryngology-Head and Neck Surgery, University of; California, San Francisco 94143.
Healing groups: awareness of a group field.: NLN Publ. 1994 Apr;(15-2610):119-29. Unique Identifier : AIDSLINE MED/94301739; Sargent S
[Cytomegalovirus infection--a review]: Nord Med. 1994;109(1):9-12. Unique Identifier : AIDSLINE MED/94301770; Hansen KK; Backer V; Skinhoj P; Infektionsmedicinsk afd, Hvidovre Hospital.; Once considered to be an infrequent cause of human disease, human cytomegalovirus ( CMV ) is now recognized as being one of the most common congenital infections leading to birth defects, and furthermore, it is a common opportu
A high-throughput, non-radioactive microtiter plate assay for activity of the human immunodeficiency virus integrase protein.: Nucleic Acids Res. 1994 Jun 11;22(11):2176-7. Unique Identifier : AIDSLINE MED/94301808; Vink C; Banks M; Bethell R; Plasterk RH; Division of Molecular Biology, The Netherlands Cancer Institute,; Amsterdam.
Nursing in prisons. Fighting addiction in prisons.: Nurs Times. 1994 Jun 15-21;90(24):30-2. Unique Identifier : AIDSLINE MED/94301831; Burrows R; This paper examines the steps which nurses and other health care staff can take to lessen the likelihood that prisoners will take ilicit drugs--both during their sentences and following release. It presents a range of possible approaches, ranging from the relatively straightforward to the sophisticated, from which nur
Gastrointestinal problems in patients with AIDS.: Nurs Times. 1994 Jun 22-28;90(25):36-9. Unique Identifier : AIDSLINE MED/94301852; Winson G; There is a complex relationship between malnutrition and immune function. Patients with chronic immunological disorders often become malnourished as a result of disease complications. On the other hand, macronutrient deficiencies are associated with the development of immunological deficiencies which are reversible on
[Use of high-dose intravenous immunoglobulins in pediatric hematology]: Pediatr Med Chir. 1994 Jan-Feb;16(1):37-41. Unique Identifier : AIDSLINE MED/94301866; Massolo F; Flori C; Cellini M; Baraldi C; Iori G; Istituto di Clinica Pediatrica, Universita degli Studi di; Modena, Italia.; High-dose intravenous immunoglobulin play a critical role in a lot of pediatric hematologic diseases. In our experience we studied the effects of IVIG treatment in 63 children. They all tolerated IVIG preparations in every infusions; no trouble caused the interruption of treatment. The efficacy is evident in immunomed
[Occurrence of free receptor for interleukin 2 in serum and quantitative determinations of CD25+ in patients infected with HIV]: Pol Arch Med Wewn. 1994 Mar;91(3):201-5. Unique Identifier : AIDSLINE MED/94301906; Radkowski M; Kopicz-Kaminska E; Laskus T; Rogers S; Babiuch L; Slusarczyk J; Zaklad Immunopatologii, Instytut Chorob Zakaznych i; Pasozytniczych Akademii Medycznej, Warszawie.; Serum soluble interleukin 2 receptor (sIL-2R) concentration and the percentage of lymphocytes presenting this receptor (CD25+) were investigated in 28 asymptomatic HIV carriers or patients with lymphadenopathy only and in 15 AIDS patients. The levels of sIL-2R were found to be higher in AIDS patients (mean 1060 U/ml)
Recent advances in the neurology of HIV infection.: Postgrad Med J. 1994 Jun;70(824):393-403. Unique Identifier : AIDSLINE MED/94301946; Petty RK; Institute of Neurological Sciences, Southern General Hospital,; Glasgow, UK.
[Primary prophylaxis against cerebral toxoplasmosis. Efficacy of folinic acid in the prevention of hematologic toxicity of pyrimethamine]: Presse Med. 1994 Apr 2;23(13):613-5. Unique Identifier : AIDSLINE MED/94301980; Brossard G; Neau D; Barbeau P; Pellegrin JL; Leng B; Clinique de Medecine interne et Maladies infectieuses, Hopital; Haut Leveque (CHU de Bordeaux), Pessac.; OBJECTIVES: Cerebral toxoplasmosis is the most frequent opportunistic infection in patients with acquired immune deficiency syndrome in France . We evaluated the effect of adding folic acid to the standard treatment (including pyrimethamine) on preventing induced cytopenia in order
[Septicemia and purulent meningitis caused by Pasteurella multocida in a HIV positive patient (letter; comment)]: Presse Med. 1994 Apr 2;23(13):631. Unique Identifier : AIDSLINE MED/94301990; Guerin JM; Mofredj A; Raskine L; Leibinger F
Appetite and nutrition in relation to human immunodeficiency virus (HIV) infection and acquired immunodeficiency virus syndrome (AIDS).: Proc Nutr Soc. 1994 Mar;53(1):139-50. Unique Identifier : AIDSLINE MED/94302016; Summerbell C; Rank Department of Human Nutrition, St Bartholomew's Hospital; Medical College, London.
Sex, drugs and AIDS: issues for hospitalized emotionally disturbed youth.: Psychiatr Q. 1994 Summer;65(2):149-55. Unique Identifier : AIDSLINE MED/94302196; Di Scipio WJ; Albert Einstein College of Medicine, Bronx, NY 10461.; Children and youth with serious and persistent emotional disturbances are becoming increasingly more at risk for HIV transmission, particularly when considering the high incidence of child sexual abuse by infected adults among the impoverished, urban population. Brief psychiatric hospitalization affords an opportunity
Cytomegalovirus pneumonitis: spectrum of parenchymal CT findings with pathologic correlation in 21 AIDS patients.: Radiology. 1994 Aug;192(2):451-9. Unique Identifier : AIDSLINE MED/94302235; McGuinness G; Scholes JV; Garay SM; Leitman BS; McCauley DI; Naidich DP; Department of Radiology, New York University Medical Center/Tisch; Hospital, NY 10016.; PURPOSE: To identify characteristic features of cytomegalovirus ( CMV ) pneumonitis at computed tomography (CT), particularly markers that may help differentiate CMV from Pneumocystis carinii pneumonia. MATERIALS AND METHODS: B
Clinical manifestations and diagnostic imaging in patients with HIV infection.: Rays. 1994 Jan-Mar;19(1):1-3. Unique Identifier : AIDSLINE MED/94302306; Marano P; Istituto di Radiologia, Universita Cattolica del S. Cuore,; Policlinico A. Gemelli, Roma.
Histopathology of HIV infection and problems of diagnostic imaging.: Rays. 1994 Jan-Mar;19(1):29-38. Unique Identifier : AIDSLINE MED/94302308; Capelli A; Zannoni GF; Istituto di Anatomia Patologica, Universita Cattolica del S.; Cuore, Policlinico A. Gemelli, Roma.
Opportunistic infections of central nervous system in immunocompromised patients.: Rays. 1994 Jan-Mar;19(1):39-50. Unique Identifier : AIDSLINE MED/94302309; Moroni M; Gervasoni C; Coppin P; Testa L; D'Arminio Monforte A; Clinica delle Malattie Infettive, Universita di Milano.
The natural history of HIV infection. Development, clinical and humoral parameters of the disease.: Rays. 1994 Jan-Mar;19(1):4-14. Unique Identifier : AIDSLINE MED/94302310; Ortona L; Marasca G; Istituto di Clinica delle Malattie Infettive, Universita; Cattolica del S. Cuore, Policlinico A. Gemelli, Roma.
Diagnostic imaging of HIV-related intracranial expansive lesions.: Rays. 1994 Jan-Mar;19(1):51-67. Unique Identifier : AIDSLINE MED/94302311; Moschini M; Tartaglione T; Rollo M; Fileni A; Colosimo C; Istituto di Radiologia, Universita Cattolica del S. Cuore,; Policlinico A. Gemelli, Roma.
Diagnostic imaging of HIV-related intracranial non expansive lesions and myelopathies.: Rays. 1994 Jan-Mar;19(1):68-86. Unique Identifier : AIDSLINE MED/94302312; Carella A; Andreula C; Cattedra e Servizio di Neuroradiologia, Universita di Bari.
Nuclear medicine in HIV-related CNS infections.: Rays. 1994 Jan-Mar;19(1):87-96. Unique Identifier : AIDSLINE MED/94302313; Pigorini F; Pau FM; Leonetti C; Galgani S; Rosci MA; Servizio di Medicina Nucleare, Ospedale Forlanini, Roma.
The promise of immunotherapy for tuberculosis [editorial]: Respir Med. 1994 Jan;88(1):3-7. Unique Identifier : AIDSLINE MED/94302337; Stanford JL; Grange JM
[The anti-viral agents used in the treatment of AIDS]: Soins. 1994 May;(584):55-7. Unique Identifier : AIDSLINE MED/94302569; Portet-Brunet L
Fear of AIDS litigation. Courts say seriousness of potential harm outweighs low risk of transmission.: Tex Med. 1994 May;90(5):40-2. Unique Identifier : AIDSLINE MED/94302608; Graddy B
AIDS and the ADA. Reasonable referral or refusal to treat?: Tex Med. 1994 May;90(5):42-5. Unique Identifier : AIDSLINE MED/94302609; Hughes MB; Gonzalez SM
Human immunodeficiency virus and the substance abuser: public policy considerations.: Tex Med. 1994 May;90(5):64-7. Unique Identifier : AIDSLINE MED/94302610; Ruiz P; Fernandez F; Department of Psychiatry and Behavioral Sciences, University of; Texas-Houston Health Science Center 77030.; Until recently, the abuse of intravenous drugs was perceived as a problem of the United States , and the acquired immunodeficiency syndrome (AIDS) epidemic was seen mainly as a sexually transmitted disease that tended to affect homosexuals from industrialized nations. However, these per
Accessory enteric nutrition.: Transplant Proc. 1994 Jun;26(3):1649. Unique Identifier : AIDSLINE MED/94302992; Guvenc BH; Salman T; Surmen E; Savci N; Celik A; Altug T; Department of Pediatric Surgery, Medical Faculty of Istanbul,; Turkey.
Differential effect of tumor necrosis factor-alpha and herpes simplex virus type 1 on the Tat-targeted inhibition of human immunodeficiency virus type 1 replication.: Virology. 1994 Aug 1;202(2):521-9. Unique Identifier : AIDSLINE MED/94303167; Popik W; Pitha PM; Oncology Center, Johns Hopkins University School of Medicine,; Baltimore, Maryland 21231.; In this study, we have examined whether the Tat antagonist can inhibit human immunodeficiency virus type 1 (HIV-1) replication in the presence of cofactors that can activate transcription of HIV-1 provirus by an NF-kappa B-mediated mechanism, such as tumor necrosis factor-alpha (TNF-alpha) or herpes simplex virus type
Mutations within the transmembrane glycoprotein of Mason-Pfizer monkey virus: loss of SU-TM association and effects on infectivity.: Virology. 1994 Aug 1;202(2):673-83. Unique Identifier : AIDSLINE MED/94303182; Brody BA; Kimball MG; Hunter E; Department of Microbiology, University of Alabama at Birmingham; 35294.; We have previously reported that an 11-amino-acid deletion (D33) within the immunosuppressive peptide (ISP) region of the Mason- Pfizer monkey virus transmembrane (TM) glycoprotein, gp22, caused the loss of interaction between TM and the surface (SU) glycoprotein, gp70. Thi
Nucleotide sequence analysis of puma lentivirus (PLV-14): genomic organization and relationship to other lentiviruses.: Virology. 1994 Aug 1;202(2):853-64. Unique Identifier : AIDSLINE GENBANK/U03983; Langley RJ; Hirsch VM; O'Brien SJ; Adger-Johnson D; Goeken RM; Olmsted RA; Laboratory of Infectious Diseases, National Institute of Allergy; and Infectious Diseases, Rockville, Maryland 20852.; The complete nucleotide sequence of an isolate of puma lentivirus (PLV-14) was obtained by an inverse polymerase chain reaction (I-PCR) technique and confirmed by conventional PCR. Both methods were used to amplify overlapping regions of proviral DNA, for cloning and sequencing, from genomic DNA isolated from PLV-14 i
Development of cowpea mosaic virus as a high-yielding system for the presentation of foreign peptides.: Virology. 1994 Aug 1;202(2):949-55. Unique Identifier : AIDSLINE MED/94303210; Porta C; Spall VE; Loveland J; Johnson JE; Barker PJ; Lomonossoff GP; Department of Virus Research, John Innes Institute, Norwich,; United Kingdom.; It has recently been shown that cowpea plants can be infected with a cowpea mosaic virus (CPMV) chimera containing an antigenic site from foot-and-mouth disease virus (Usha et al., Virology 197, 366-374, 1993). Analysis of progeny RNA produced during such an infection has revealed that the inserted sequence is rapidly
Functional consequences of mutations in HIV-1 Gag p55 selected by CTL pressure.: Virology. 1994 Aug 15;203(1):101-5. Unique Identifier : AIDSLINE MED/94303221; Zhang WH; Hockley DJ; Nermut MV; Jones IM; NERC Institute of Virology, Oxford, United Kingdom.; Amino acid changes in the CA domain of the p55 Gag protein of HIV-1 have been observed during the course of an infection that appear to correlate with escape from cytotoxic T cell surveillance (Phillips et al., Nature 354, 453-459, 1991). A corollary of this observation is that all such changes should be functionally
Occurrence of human papillomavirus and p53 gene mutations in Kaposi's sarcoma.: Virology. 1994 Aug 15;203(1):153-7. Unique Identifier : AIDSLINE MED/94303228; Scinicariello F; Dolan MJ; Nedelcu I; Tyring SK; Hilliard JK; Department of Virology and Immunology, Southwest Foundation for; Biomedical Research, San Antonio, Texas 78228-0147.; Epidemiological evidence indicates that a sexually transmitted agent might be involved in the etiopathogenesis of Kaposi s sarcoma (KS). The prevalence of human papillomaviruses (HPV) in KS has been the focus of several investigations that have reported conflicting data. In addition, mutations of the p53 gene, which a
Site-directed mutagenesis of the P2 region of the Rous sarcoma virus gag gene: effects on Gag polyprotein processing.: Virology. 1994 Aug 15;203(1):20-8. Unique Identifier : AIDSLINE MED/94303238; Bowles N; Bonnet D; Mulhauser F; Spahr PF; Department of Molecular Biology, University of Geneva,; Switzerland.; The Pr76Gag and Pr180Gag-Pol polyprotein precursors of Rous sarcoma virus contain a 22-amino-acid spacer peptide, called p2, located between the amino acid sequences of the mature Gag proteins MA and p10. This spacer peptide is present in stoichiometric amounts in the virion, albeit cleaved into two parts, but its fun
In vivo genetic variability of the HIV-1 vif gene.: Virology. 1994 Aug 15;203(1):43-51. Unique Identifier : AIDSLINE +; Wieland U; Hartmann J; Suhr H; Salzberger B; Eggers HJ; Kuhn JE; Institut fur Virologie, Universitat zu Koln, Germany.; The human immunodeficiency virus type 1 (HIV-1) vif gene encodes a 23-kDa protein (viral infectivity factor) whose exact mechanism of action is not entirely clear. Vif is believed to be highly conserved among different HIV-1 strains. We have analyzed the proviral vif sequences of 61 peripheral blood mononuclear cell s
Complex genome organization in the GNS-L intergenic region of Adelaide River rhabdovirus.: Virology. 1994 Aug 15;203(1):63-72. Unique Identifier : AIDSLINE GENBANK/U05987; Wang Y; McWilliam SM; Cowley JA; Walker PJ; CSIRO Division of Tropical Animal Production, Indooroopilly,; Queensland, Australia.; A 2341-nucleotide region of the Adelaide River virus (ARV) genome, located immediately downstream of the second glycoprotein (GNS) gene, has been cloned and sequenced. The region contains four long open reading frames (ORFs), the last of which represents a 1088-nucleotide fragment at the start of the ARV L gene. Betwe
Effects of cytoplasmic domain length on cell surface expression and syncytium-forming capacity of the simian immunodeficiency virus envelope glycoprotein.: Virology. 1994 Aug 15;203(1):8-19. Unique Identifier : AIDSLINE MED/94303245; Spies CP; Compans RW; Department of Microbiology, University of Alabama at Birmingham; 35294-0005.; We previously reported that truncation of the terminal 146 amino acids of the macaque simian immunodeficiency virus SIVmac239 envelope glycoprotein enhanced envelope-specific syncytium formation in HeLa T4, CEM X 174, and HUT 78 cell lines and caused a change in the conformation of the transmembrane subunit of the env
Tear lactoferrin levels and ocular bacterial flora in HIV positive patients.: Adv Exp Med Biol. 1994;350:339-44. Unique Identifier : AIDSLINE MED/94303516; Comerie-Smith SE; Nunez J; Hosmer M; Farris RL; Department of Ophthalmology, Harlem Hospital Center, New York,; NY.; Keratoconjunctivitis Sicca(4) has recently been reported to occur at a greater rate in HIV-positive symptomatic patients. We looked at HIV positive asymptomatic patients, compared to age matched HIV negative patients to study external ocular resistant factors, namely lactoferrin levels in tears, bacterial flora in lid
Lacrimal dysfunction in pediatric acquired immunodeficiency syndrome.: Adv Exp Med Biol. 1994;350:517-20. Unique Identifier : AIDSLINE MED/94303547; Neves RA; de Freitas D; Sato E; Oliveira C; Belfort Junior R; Department of Ophthalmology, Escola Paulista de Medicina, S.; Paulo, Brazil.
Keratoconjunctivitis sicca in HIV-1 infected female patients.: Adv Exp Med Biol. 1994;350:521-3. Unique Identifier : AIDSLINE MED/94303548; Lucca JA; Kung JS; Farris RL; Department of Ophthalmology, Columbia University, New York, NY.
Effect of sexual behavior change on long-term human immunodeficiency virus prevalence among homosexual men.: Am J Epidemiol. 1994 Aug 1;140(3):217-32. Unique Identifier : AIDSLINE MED/94303657; Morris M; Dean L; Department of Sociology, Columbia University, New York, NY 10025.; Substantial changes in human immunodeficiency virus (HIV)-related sexual behavior have been reported by virtually every survey of homosexual/bisexual men in the last decade. This paper uses a behavior-based simulation to examine how such changes are likely to affect the long-term future of the acquired immunodeficienc
Thrombocytopenia in pregnant women infected with human immunodeficiency virus: maternal and neonatal outcome.: Am J Obstet Gynecol. 1994 Jul;171(1):252-7. Unique Identifier : AIDSLINE MED/94303746; Mandelbrot L; Schlienger I; Bongain A; Berrebi A; Pons JC; Ciraru-Vigneron N; Gillet JY; Delfraissy JF; Department of Obstetrics-Gynecology, Hopital Robert Debre,; Paris, France.; OBJECTIVES: Our purpose was to evaluate the prevalence of thrombocytopenia related to human immunodeficiency virus among seropositive pregnant women and its impact on maternal and neonatal outcome. STUDY DESIGN: A retrospective survey of all deliveries of women infected with human immunodeficiency virus in 14 maternit
Oncostatin-M is an autocrine growth factor in Kaposi's sarcoma.: Am J Pathol. 1994 Jul;145(1):74-9. Unique Identifier : AIDSLINE MED/94303804; Cai J; Gill PS; Masood R; Chandrasoma P; Jung B; Law RE; Radka SF; Department of Medicine and Pathology, University of Southern; California School of Medicine, Los Angeles.; Oncostatin-M is a cytokine produced by macrophages and activated T lymphocytes that has recently been shown to be a mitogen for AIDS-related Kaposi s sarcoma (KS)-derived spindle cells. The significance of oncostatin-M production in AIDS-related KS in vivo, however, remains unknown. In this study we wanted to determin
Infection of the central nervous system by human retroviruses.: Ann N Y Acad Sci. 1994 Jun 6;724:125-32. Unique Identifier : AIDSLINE MED/94303989; Michaels FH; Gallo RC; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.
Sequence variation in the envelope gene and the LTR of maedi-visna virus.: Ann N Y Acad Sci. 1994 Jun 6;724:157-8. Unique Identifier : AIDSLINE MED/94303994; Andresdottir V; Tang X; Andresson OS; Georgsson G; Institute for Experimental Pathology, University of Iceland,; Keldur, Reykjavik.
Pathogenesis of central nervous system lesions in visna cell-mediated immunity and lymphocyte subsets in blood, brain, and cerebrospinal fluid.: Ann N Y Acad Sci. 1994 Jun 6;724:159-61. Unique Identifier : AIDSLINE MED/94303995; Torsteinsdottir S; Georgsson G; Gisladottir E; Rafnar B; Palsson PA; Petursson G; Institute for Experimental Pathology, University of Iceland,; Keldur, Reykjavik.; The time course and titers of antibodies did not correlate with the severity of CNS lesions whereas the CMI did, indicating that CMI may play an important role in lesion development. The correlation of the number of CD8 positive cells in the CSF with the severity of lesions and the reversed ratio of CD4/CD8 positive c
Lectin effects on HIV-1 infectivity.: Ann N Y Acad Sci. 1994 Jun 6;724:166-9. Unique Identifier : AIDSLINE MED/94303997; Hammar L; Hirsch I; Machado A; De Mareuil J; Baillon J; Chermann JC; Department of Veterinary Virology, Biomedical Center, Uppsala,; Sweden.; Lectins with specificity for terminal mannose residues and anti-mannan antibodies are assumed to neutralize HIV-1 by binding to the viral glycoproteins. In this report we demonstrate that one such agents, the lectin from Galanthus nivalis (GNA), blocks infection also at the target cell level.
Diagnosis of virus-associated opportunistic diseases of the central nervous system in patients with HIV infection by polymerase chain reaction on cerebrospinal fluid.: Ann N Y Acad Sci. 1994 Jun 6;724:170-2. Unique Identifier : AIDSLINE MED/94303998; Cinque P; Brytting M; Vago L; Castagna A; D'Arminio Monforte A; Lazzarin A; Linde A; Department of Virology, National Bacteriological Laboratory,; Stockholm, Sweden.
In situ PCR for the detection of HTLV-I in HAM/TSP patients.: Ann N Y Acad Sci. 1994 Jun 6;724:404-13. Unique Identifier : AIDSLINE MED/94304031; Walter MJ; Lehky TJ; Fox CH; Jacobson S; Howard Hughes Medical Institute, Bethesda, Maryland 20892.
Role of monocyte/macrophage lineage cells in HAM/TSP.: Ann N Y Acad Sci. 1994 Jun 6;724:414-6. Unique Identifier : AIDSLINE MED/94304032; Iwasaki Y; Akizuki S; Miwa M; Department of Neurological Sciences, Tohoku University School of; Medicine, Sendai, Japan.
Molecular characterization of HTLV-I infection in Israel.: Ann N Y Acad Sci. 1994 Jun 6;724:417-21. Unique Identifier : AIDSLINE MED/94304033; Danon YL; Kilim Y; Rosenblatt JD; Kipper Institute of Immunology, Children's Medical Center of; Israel, Sackler School of Medicine, Tel-Aviv University.
HTLV-I hu-SCID mouse in the study of HTLV-I neurotropism.: Ann N Y Acad Sci. 1994 Jun 6;724:422-5. Unique Identifier : AIDSLINE MED/94304034; Furlan R; Salazar-Grueso EF; Martino G; Lillo F; Kotulski M; Brambilla E; Castellano M; Terreni MR; Roos RP; Grimaldi LM; Department of Neurology, University of Milano, IRCCS H. San; Raffaele, Italy.
Inactivation of enveloped viruses in human bodily fluids by purified lipids.: Ann N Y Acad Sci. 1994 Jun 6;724:457-64. Unique Identifier : AIDSLINE MED/94304040; Isaacs CE; Kim KS; Thormar H; Department of Developmental Biochemistry, New York State; Institute for Basic Research in Developmental Disabilities,; Staten Island 10314.; Antimicrobial lipids are found in mucosal secretions and are one of a number of nonimmunologic and nonspecific protective factors found at mucosal surfaces. Lipids can inactivate enveloped viruses, bacteria, fungi, and protozoa. Lipid-dependent antimicrobial activity at mucosal surfaces is due to certain monoglyceride
Neuropathologic aspects of lentiviral infections.: Ann N Y Acad Sci. 1994 Jun 6;724:50-67. Unique Identifier : AIDSLINE MED/94304044; Georgsson G; Institute for Experimental Pathology, University of Iceland,; Keldur v/Vesturlandsveg, Reykjavik.; Studies of lentiviral infections of various animals and man have shown that all may invade the CNS and induce pathological lesions. This is well established in infections with VV, CAEV, SIV, HIV-1, and FIV. Although VV and CAEV do not cause an overt immunodeficiency, they share several features pertinent for the estab
Slow infections of the central nervous system caused by conventional viruses.: Ann N Y Acad Sci. 1994 Jun 6;724:6-13. Unique Identifier : AIDSLINE MED/94304045; Johnson RT; Department of Neurology, Johns Hopkins University School of; Medicine, Baltimore, Maryland 21287-7609.
The role of active and covert infections in lentivirus pathogenesis.: Ann N Y Acad Sci. 1994 Jun 6;724:75-86. Unique Identifier : AIDSLINE MED/94304047; Haase AT; Department of Microbiology, University of Minnesota, Minneapolis; 55455-0312.
Pathogenesis of HIV encephalopathy.: Ann N Y Acad Sci. 1994 Jun 6;724:87-106. Unique Identifier : AIDSLINE MED/94304048; Nathanson N; Cook DG; Kolson DL; Gonzalez-Scarano F; Department of Microbiology, University of Pennsylvania Medical; Center, Philadelphia 19104-6076.
Alternating versus continuous drug regimens in combination chemotherapy of human immunodeficiency virus type 1 infection in vitro.: Antimicrob Agents Chemother. 1994 Apr;38(4):656-61. Unique Identifier : AIDSLINE MED/94304105; Mazzulli T; Rusconi S; Merrill DP; D'Aquila RT; Moonis M; Chou TC; Hirsch MS; Infectious Disease Unit, Massachusetts General Hospital, Harvard; Medical School, Boston 02114.; We compared the in vitro efficacies of two-, three-, and four-drug combinations given continuously or in alternating regimens against a clinical isolate of human immunodeficiency virus type 1. In H9 cells and peripheral blood mononuclear cells, at the drug concentrations used in this study, there was greater suppressi
Pharmacokinetics and safety of levofloxacin in patients with human immunodeficiency virus infection.: Antimicrob Agents Chemother. 1994 Apr;38(4):799-804. Unique Identifier : AIDSLINE MED/94304129; Goodwin SD; Gallis HA; Chow AT; Wong FA; Flor SC; Bartlett JA; Department of Medicine, Duke University Medical Center, Durham,; North Carolina.; Levofloxacin, the bacteriologically active isomer of ofloxacin, has microbiologic activity against many pathogens common in human immunodeficiency virus (HIV)-infected patients, including Mycoplasma species which may be cofactors in the progression of HIV disease. The purpose of this phase I, double-blind, randomized
Multiple-drug-resistant mutants of feline immunodeficiency virus selected with 2',3'-dideoxyinosine alone and in combination with 3'-azido-3'-deoxythymidine.: Antimicrob Agents Chemother. 1994 Apr;38(4):861-4. Unique Identifier : AIDSLINE MED/94304140; Gobert JM; Remington KM; Zhu YQ; North TW; Division of Biological Sciences, University of Montana, Missoula; 59812.; Mutants of feline immunodeficiency virus (FIV) were selected in cell culture in the continuous presence of 10 microM (each) 3 -azido-3 -deoxythymidine ( AZT ) and 2 ,3 -dideoxyinosine (ddI). These mutants (AIR-1 and AIR-3) displayed a 13-fold resistance
Effect of antacids in didanosine tablet on bioavailability of isoniazid.: Antimicrob Agents Chemother. 1994 Apr;38(4):894-7. Unique Identifier : AIDSLINE MED/94304149; Gallicano K; Sahai J; Zaror-Behrens G; Pakuts A; Bureau of Drug Research, Sir Frederick Banting Research Centre,; Ottawa, Ontario, Canada.; The antacids in two didanosine placebo tablets had no significant effect on the plasma pharmacokinetics of a single oral dose of 300 mg of isoniazid administered to 12 healthy volunteers. These results suggest that isoniazid bioavailability will be unaffected by the antacids in didanosine tablets when the two medicati
[Recent progress in the treatment of malignant lymphoma]: Gan To Kagaku Ryoho. 1994 Jul;21(8):1151-6. Unique Identifier : AIDSLINE MED/94304242; Tobinai K; Shimoyama M; Department of Medical Oncology, National Cancer Center Hospital,; Tokyo, Japan.; Recent progress in the chemotherapy for malignant lymphoma is reviewed. From the viewpoint of treatment, malignant lymphoma is classified into five major categories; aggressive lymphoma, indolent B-lymphoma, Hodgkin s disease, T-lymphoblastic lymphoma and adult T-cell leukemia-lymphoma (ATL). Based on the results of t
[Chemotherapy of AIDS in children]: Antibiot Khimioter. 1993 Apr-May;38(4-5):70-4. Unique Identifier : AIDSLINE MED/94304292; Chizhov NP
Esophageal disease in human immunodeficiency virus infection.: Arch Intern Med. 1994 Jul 25;154(14):1577-82. Unique Identifier : AIDSLINE MED/94304297; Laine L; Bonacini M; Department of Medicine, University of Southern California School; of Medicine, Los Angeles.; Up to 40% of patients with the acquired immunodeficiency syndrome may develop symptoms of esophageal disease. Candida esophagitis is responsible for the majority of the cases of esophageal disease; cytomegalovirus , herpes simplex, idiopathic esophageal ulcers, and Kaposi s sarcoma
Exposure of p19 matrix protein of human T-cell leukemia virus type I (HTLV-I) on the surface of MOLT-4#8 cells after virus adsorption.: Arch Virol. 1994;136(3-4):389-95. Unique Identifier : AIDSLINE MED/94304337; Akari H; Kuroda MJ; Shinjo T; el-Farrash MA; Harada S; Department of Biodefence and Medical Virology, Kumamoto; University School of Medicine, Japan.; The p19 matrix (MA) protein of human T-cell leukemia virus type I (HTLV-I) was exposed on the surface of MOLT-4#8 cells in the very early step of the virus infection. Transfer of the virus-binding MOLT-4#8 cells from 4 degrees C to 37 degrees C resulted in increased detection of the viral gp46 and p19 MA protein on th
Human T-cell lymphotropic virus type I-associated retinal lymphoma. A clinicopathologic report.: Arch Ophthalmol. 1994 Jul;112(7):954-9. Unique Identifier : AIDSLINE MED/94304382; Kumar SR; Gill PS; Wagner DG; Dugel PU; Moudgil T; Rao NA; Doheny Eye Institute, University of Southern California School of; Medicine, Los Angeles.; Human T-cell lymphotropic virus type I has been associated with a wide range of ocular conditions, including neoplastic, infectious, and inflammatory lesions. We studied a patient infected with human T-cell lymphotrophic virus type I who presented with deep retinal and subretinal infiltrates but without cells in the v
Antiviral activity of a sulphated polysaccharide from the red seaweed Nothogenia fastigiata.: Biochem Pharmacol. 1994 Jun 15;47(12):2187-92. Unique Identifier : AIDSLINE MED/94304422; Damonte E; Neyts J; Pujol CA; Snoeck R; Andrei G; Ikeda S; Witvrouw M; Reymen D; Haines H; Matulewicz MC; et al; Departamento de Quimica Biologica, Facultad de Ciencias Exactas y; Naturales, Universidad de Buenos Aires, Argentina.; The antiviral activity of polysaccharide fractions obtained from water extracts of the red seaweed Nothogenia fastigiata was investigated. Fraction F6, corresponding to a sulphated xylomannan, was found to inhibit efficiently the replication of herpes simplex virus type 1 (HSV-1). Furthermore, F6 selectively inhibited
[A new prophylactic agent in AIDS: Ansatipine. Disseminated Mycobacterium avium complex infection is now the most frequent of the opportunistic bacterial infections in AIDS]: Allerg Immunol (Paris). 1994 Apr;26(4):141-4. Unique Identifier : AIDSLINE MED/94304496; Dautzenberg B; Service des Maladies Respiratoires, Groupe Hospitalier Pitie-; Salpetriere, Paris.; Otherwise infrequent, infections by non-tuberculous or atypical mycobacteria are now rising in AIDS. Infection with the Mycobacterium avium complex (MAC) is now the most frequent opportunistic bacterial infection, because of better detection of HIV positive patients. The incidence, which is probably underestimated, is
[Ansatipine: only preventive treatment available for opportunistic MAI infections in AIDS. From an interview with Dr. Agnes Mignon]: Allerg Immunol (Paris). 1994 Apr;26(4):148, 151-3. Unique Identifier : AIDSLINE MED/94304498; Mignon A; Laboratoires Pharmacia, Saint-Quentin-en-Yvelines.; Ansatipine, the international name of which is rifabutine, is a new specialty that was licensed in February 1993 and marketed in France in June 1993. It is an antibiotic of the rifamycin family, the result of research by Farmitalia Carlo Erba and is now presented by the Laboratoire
[Opportunistic infections in AIDS: the benefits of an umbrella strategy. From an interview with Professor Willy Rozenbaum]: Allerg Immunol (Paris). 1994 Apr;26(4):153-5. Unique Identifier : AIDSLINE MED/94304499; Rozenbaum W; Service des Maladies Infectieuses, Hopital Rothschild, Pris.; Availability to practitioners of a treatment for infections by atypical mycobacteria by Ansatipine should produce a reduction or delay in the frequency of opportunistic infections in AIDS, which are a heavy burden on the future of the patients and seriously after their quality of life. Today, the practice of prescribi
[Prevention of MAI infections in AIDS with Ansatipine: experience at a hospital. From an interview with Dr. Jean-Luc Meynard]: Allerg Immunol (Paris). 1994 Apr;26(4):155-7. Unique Identifier : AIDSLINE MED/94304500; Meynard JL; Service des Maladies Infectieuses et Tropicales du Pr Frottier,; Hopital Saint-Antoine, Paris.; Nowadays, infections by the Mycobacterium avium complex (MAC) have become amongst the most frequent of the opportunistic bacterial infections in AIDS, following the introduction of prophylaxis to pneumocystosis and toxoplasmosis. MAC infections are recognised as a serious pathology that quickly causes hidden condition
Anal human papillomavirus infection and anal cancer in HIV-positive individuals: an emerging problem [editorial]: AIDS. 1994 Mar;8(3):283-95. Unique Identifier : AIDSLINE MED/94304548; Palefsky JM
Differential replication and pathogenic effects of HIV-1 and HIV-2 in Macaca nemestrina.: AIDS. 1994 Mar;8(3):297-306. Unique Identifier : AIDSLINE GENBANK/L08465; Otten RA; Brown BG; Simon M; Lupo LD; Parekh BS; Lairmore MD; Schable CA; Schochetman G; Rayfield MA; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, GA 30333.; OBJECTIVE: HIV-1 and HIV-2 isolates representing various geographic regions and distinct viral subtypes were examined for their ability to establish both in vitro and in vivo productive infections of Macaca nemestrina (pigtail macaque) peripheral blood mononuclear cells. METHODS: Animals were inoculated with either au
Acetylation phenotype and cutaneous hypersensitivity to trimethoprim-sulphamethoxazole in HIV-infected patients.: AIDS. 1994 Mar;8(3):333-7. Unique Identifier : AIDSLINE MED/94304553; Carr A; Gross AS; Hoskins JM; Penny R; Cooper DA; Centre for Immunology, St Vincent's Hospital, Sydney, Australia.; OBJECTIVE: Hypersensitivity to trimethoprim-sulphamethoxazole (TMP-SMX) is more common in patients with HIV infection. In non-infected patients, TMP-SMX hypersensitivity is more common in those with a slow acetylator phenotype. This study was conducted to determine whether the slow acetylation phenotype is associated
Impact of HIV infection on non-AIDS mortality among Italian injecting drug users.: AIDS. 1994 Mar;8(3):345-50. Unique Identifier : AIDSLINE MED/94304555; Zaccarelli M; Gattari P; Rezza G; Conti S; Spizzichino L; Vlahov D; Ippolito G; Lelli V; Valenzi C; Drug Treatment Centre and AIDS Unit USL-RM10, Rome, Italy.; OBJECTIVES: To estimate the excess mortality of injecting drug users (IDU) stratified by HIV serostatus compared with the general population in Italy . To compare total and cause-specific mortality in HIV-positive versus HIV-negative IDU, in order to identify possible HIV-related non
Seroconversion in patients attending sexually transmitted disease clinics.: AIDS. 1994 Mar;8(3):351-5. Unique Identifier : AIDSLINE MED/94304556; Kassler WJ; Zenilman JM; Erickson B; Fox R; Peterman TA; Hook EW 3rd; Division of STD/HIV Prevention, Centers for Disease Control,; Atlanta, GA 30333.; OBJECTIVES: To characterize recent HIV seroconverters in a sexually transmitted disease (STD) clinic population, and examine changing transmission patterns. METHODS: We conducted a case-control study nested within a retrospectively defined cohort of individuals attending Baltimore STD clinics between January 1988 and
Consistent condom use in relationships between seropositive injecting drug users and sex partners who do not inject drugs.: AIDS. 1994 Mar;8(3):357-61. Unique Identifier : AIDSLINE MED/94304557; Friedman SR; Jose B; Neaigus A; Goldstein M; Curtis R; Ildefonso G; Mota P; Des Jarlais DC; National Development and Research Institutes (NDRI), Inc., New; York, NY 10013.; OBJECTIVES: To study how condom use in injecting drug users (IDU) relationships differs according to whether they are HIV-infected, and to whether their sex partner is an IDU. DESIGN AND METHODS: A total of 317 street-recruited IDU were HIV-antibody tested and interviewed about 421 relationships with particular sex p
High mortality among HIV-infected injecting drug users without AIDS diagnosis: implications for HIV infection epidemic modellers?: AIDS. 1994 Mar;8(3):363-6. Unique Identifier : AIDSLINE MED/94304558; van Haastrecht HJ; van den Hoek AJ; Coutinho RA; Municipal Health Service, Department of Public Health and; Environment, Amsterdam, The Netherlands.; OBJECTIVE: To quantify mortality without AIDS diagnosis (pre-AIDS death) among HIV-infected injecting drug users (IDU) and to compare it with that among homosexual men. SETTING: Municipal Health Service in Amsterdam, The Netherlands . DESIGN: HIV-infected participants of a coho
Changing use of hospital services and costs at a London AIDS referral centre, 1983-1989.: AIDS. 1994 Mar;8(3):367-77. Unique Identifier : AIDSLINE MED/94304559; Beck EJ; Kennelly J; McKevitt C; Whitaker L; Wadsworth J; Miller DL; Easmon C; Pinching AJ; Harris JR; Academic Department of Public Health, St Mary's Hospital and; Medical School, London, UK.; OBJECTIVE: To describe the use of hospital-based services and associated costs over time for HIV-infected individuals by disease stage and year of treatment. METHODS: Data on service use were abstracted from inpatient and outpatient case-notes of 459 HIV-infected patients (121 asymptomatic and 338 AIDS patients) treat
Changing presentation and survival, service utilization and costs for AIDS patients: insights from a London referral centre.: AIDS. 1994 Mar;8(3):379-84. Unique Identifier : AIDSLINE MED/94304560; Beck EJ; Whitaker L; Kennelly J; McKevitt C; Wadsworth J; Miller DL; Easmon C; Pinching AJ; Harris JR; Academic Department of Public Health, St Mary's Hospital and; Medical School, London, UK.; OBJECTIVE: To describe the use of services and associated costs for HIV-infected patients by stage of infection in the context of changing patterns of presentation and survival. METHODS: A retrospective analysis of inpatient and outpatient case-notes of 335 AIDS patients and a survey of HIV-related care provided by 37
Active drug injecting and progression of HIV infection [editorial] [published erratum appears in AIDS 1994 Oct;8(10):1514]: AIDS. 1994 Mar;8(3):385-6. Unique Identifier : AIDSLINE MED/94304561; Phillips AN; Sabin CA; Mocroft A
Sporobolomyces salmonicolor lymphadenitis in an AIDS patient. Pathogen or passenger? [letter]: AIDS. 1994 Mar;8(3):387-8. Unique Identifier : AIDSLINE MED/94304562; Plazas J; Portilla J; Boix V; Perez-Mateo M
Inefficacy of neutralizing antibodies against autologous lymph-node HIV-1 isolates in patients with early-stage HIV infection [letter]: AIDS. 1994 Mar;8(3):388-9. Unique Identifier : AIDSLINE MED/94304563; Tamalet C; Lafeuillade A; Tourres C; Yahi N; Vignoli C; De Micco P
Anti-CD4 autoantibodies in HIV-infected individuals: detection by two immunoenzymatic techniques [letter]: AIDS. 1994 Mar;8(3):389-90. Unique Identifier : AIDSLINE MED/94304564; Martin L; Idziorek T; Lehen A; Gluckman JC; Klatzmann D
BK virus-associated haemorrhagic cystitis in an HIV-infected man [letter]: AIDS. 1994 Mar;8(3):391-2. Unique Identifier : AIDSLINE MED/94304566; Gluck TA; Knowles WA; Johnson MA; Brook MG; Pillay D
Influence of personal experience of dying AIDS patients on attitude and sexual behaviour in Kabarole district, Uganda [letter]: AIDS. 1994 Mar;8(3):392-4. Unique Identifier : AIDSLINE MED/94304567; Kipp W; Masheisha C; von Sonnenburg F; Weis P
Malignant mesothelioma in an HIV-positive patient [letter]: AIDS. 1994 Mar;8(3):394-5. Unique Identifier : AIDSLINE MED/94304568; Kordossis T; Kosmopoulou O; Zagoreos J; Dossios T; Deladetsima I; Tsavaris N; Sipsas N; Stratigos J; Papavassiliou K
What is the role of T-lymphocytes with gamma/delta receptors in Pneumocystis carinii pneumonia in AIDS patients? [letter] [see comments]: AIDS. 1994 Mar;8(3):395. Unique Identifier : AIDSLINE MED/94304569; Perrella O; Perrella A; Soscia E; Marinelli A; Mininni V; Guerriero S; Briante R; Finelli L
Mortality among female nurses in the face of the AIDS epidemic: a pilot study in Zambia [letter]: AIDS. 1994 Mar;8(3):396. Unique Identifier : AIDSLINE MED/94304570; Buve A; Foaster SD; Mbwili C; Mungo E; Tollenare N; Zeko M
Stable seroprevalence of HIV-1 in antenatal women in rural Bas-Zaire, 1988-1993 [letter]: AIDS. 1994 Mar;8(3):397-8. Unique Identifier : AIDSLINE MED/94304571; Green SD; Cutting WA; Mokili JL; Nganzi M; Hargreaves FD; Davies AG; Bopopi JM; Elton RE; Hardy IR; Jackson DJ; et al
Statistics from the Centers for Disease Control and Prevention.: AIDS. 1994 Mar;8(3):399-401. Unique Identifier : AIDSLINE MED/94304572
Inhibition of human immunodeficiency virus type-1 env expression by C-5 propyne oligonucleotides specific for Rev-response element stem-loop V.: Biochemistry. 1994 Jul 19;33(28):8391-8. Unique Identifier : AIDSLINE MED/94304852; Fenster SD; Wagner RW; Froehler BC; Chin DJ; Agouron Institute, La Jolla, California 92037.; The binding of Rev to the Rev-response element (RRE) of the human immunodeficiency virus (HIV) is essential for RNA transport and expression of structural proteins such as gp160 encoded by env. To determine if env expression could be disrupted by complementary oligodeoxynucleotides (ODNs), band-shift studies were used
X-ray crystallographic studies of a series of penicillin-derived asymmetric inhibitors of HIV-1 protease.: Biochemistry. 1994 Jul 19;33(28):8417-27. Unique Identifier : AIDSLINE MED/94304855; Jhoti H; Singh OM; Weir MP; Cooke R; Murray-Rust P; Wonacott A; Department of Biomolecular Structure, Glaxo Research &; Development Limited, Greenford, Middlesex, England.; In the development of a treatment for AIDS, the HIV-1 protease has been identified as a good target enzyme for inhibitor design. We previously reported a series of dimeric penicillin-derived C2-symmetric HIV-1 protease inhibitors [Humber, D., et al. (1993) J. Med. C
Rhodococcus equi: first case in a heart transplant recipient.: J Heart Lung Transplant. 1994 Mar-Apr;13(2):332-5. Unique Identifier : AIDSLINE MED/94304903; Segovia J; Pulpon LA; Crespo MG; Daza R; Rodriguez JC; Rubio A; Serrano S; Carreno MC; Varela A; Aranguena R; et al; Heart Transplant Unit, Clinica Puerta de Hierro, Madrid, Spain.; Rhodococcus equi is a gram-positive diphtheroid that occasionally affects immunocompromised patients, usually causing a chronic respiratory infection with cavitating pulmonary opacities on chest radiograph that resemble mycobacterial or fungal disease. Etiologic diagnosis presents a number of pitfalls, because Rhodoco
Modification of CD4 immunoadhesin with monomethoxypoly(ethylene glycol) aldehyde via reductive alkylation.: Bioconjug Chem. 1994 Mar-Apr;5(2):133-40. Unique Identifier : AIDSLINE MED/94304966; Chamow SM; Kogan TP; Venuti M; Gadek T; Harris RJ; Peers DH; Mordenti J; Shak S; Ashkenazi A; Department of Process Science, Genentech, Inc., South San; Francisco, California 94080.; CD4 immunoadhesin (CD4-IgG) is a chimeric glycoprotein molecule comprised of the gp120-binding portion of human CD4 fused to the hinge and Fc portions of human IgG. As a candidate for human therapeutic use, CD4-IgG represents an important advance over soluble CD4, insofar as the systemic clearance in humans of CD4-IgG
[A ground-glass computerized tomography image in an HIV-positive patient with a febrile syndrome]: Enferm Infecc Microbiol Clin. 1994 Apr;12(4):213-4. Unique Identifier : AIDSLINE MED/94304979; Dolors Torremorell M; Mas A; Domingo C; Mata JM; Jaen A; Servicio de Neumologia, Consorci Hospitalari del Parc Tauli,; Sabadell, Barcelona.
HIV testing and prevalence in pregnancy in Edinburgh.: Int J STD AIDS. 1994 Mar-Apr;5(2):101-4. Unique Identifier : AIDSLINE MED/94305002; Johnstone FD; Brettle RP; Burns SM; Peutherer J; Mok JY; Robertson JR; Hamilton B; Tappin DM; Department of Obstetrics and Gynaecology, University of; Edinburgh, UK.; The objective was to study the changes in pregnancy HIV prevalence with time. Data were collected from multiple sources to provide a comprehensive record of all HIV seropositive pregnant women identified in the Edinburgh area (Scotland) until December 1992. There were 177 pregnancies in 108 HIV seropositive identified
Low and stable prevalence of HIV among drug injectors in Glasgow.: Int J STD AIDS. 1994 Mar-Apr;5(2):105-7. Unique Identifier : AIDSLINE MED/94305003; Taylor A; Frischer M; Green ST; Goldberg D; McKeganey N; Gruer L; Communicable Diseases and Environmental Health (Scotland) Unit,; Ruchill Hospital, UK.; The first HIV-positive diagnosis among injecting drug users (IDU) in Glasgow was made in 1985. By the end of 1987 prevalence among IDU receiving voluntary attributable tests was 4.8%. Since 1990, an annual cross-sectional survey of HIV prevalence and risk behaviours among 500 current Glasgow IDU has provided a more re
Relationships of cervical cytologies to selected variables among women attending a sexually transmitted disease clinic.: Int J STD AIDS. 1994 Mar-Apr;5(2):108-12. Unique Identifier : AIDSLINE MED/94305004; Campbell PJ; Hewitt SH; Kowalchuk PA; Joffres M; Romanowski B; Sexually Transmitted Disease Services, Alberta Health, Edmonton,; Canada.; A retrospective chart review was conducted for one year to determine cervical cytological abnormalities and their distribution among women attending a STD clinic, and to analyse cervical cytologies by STD diagnosis and history or presence of genital warts. Analysis was performed on 790 Pap smears. Most (60%) cytologie
Prevalence of antibodies to herpes simplex virus in pregnant women in Stockholm in 1969, 1983 and 1989: implications for STD epidemiology.: Int J STD AIDS. 1994 Mar-Apr;5(2):113-6. Unique Identifier : AIDSLINE MED/94305005; Forsgren M; Skoog E; Jeansson S; Olofsson S; Giesecke J; Virus Department, Central Microbiological Laboratory, Stockholm; County Council, Sweden.; Prevalence of antibody to herpes simplex virus types 1 and 2 was assessed in consecutive serum samples from a total of 3700 women pregnant in 1969, 1983, or 1989 from the same catchment area in Stockholm. There was little change in seroprevalence of antibody to herpes simplex type 1 in the 3 groups, but age-adjusted h
Syphilis and HIV infection among displaced pregnant women in rural Mozambique.: Int J STD AIDS. 1994 Mar-Apr;5(2):117-23. Unique Identifier : AIDSLINE MED/94305006; Cossa HA; Gloyd S; Vaz RG; Folgosa E; Simbine E; Diniz M; Kreiss JK; Department of Epidemiology, University of Washington, Seattle.; A cross-sectional study was conducted among displaced pregnant women in Mozambique to determine the prevalence and correlates of HIV infection and syphilis. Between September 1992 and February 1993, 1728 consecutive antenatal attendees of 14 rural clinics in Zambezia were inter
Patterns of risk behaviour for patients with sexually transmitted diseases and surveillance for human immunodeficiency virus in Kuala Lumpur, Malaysia.: Int J STD AIDS. 1994 Mar-Apr;5(2):124-9. Unique Identifier : AIDSLINE MED/94305007; Lye MS; Archibald C; Ghazali AA; Low BT; Teoh BH; Sinniah M; Rus SC; Singh J; Nair RC; Institute for Medical Research, Kuala Lumpur, Malaysia.; A study was conducted to determine the feasibility of establishing a sentinel human immunodeficiency virus (HIV) surveillance system involving patients with sexually transmitted diseases attending private clinics and a government sexually transmitted disease clinic in Kuala Lumpur, M
Gender identity disorder and HIV disease [see comments]: Int J STD AIDS. 1994 Mar-Apr;5(2):130-2. Unique Identifier : AIDSLINE MED/94305008; Pang H; Pugh K; Catalan J; Department of Psychological Medicine, Charing Cross and; Westminster Medical School, London, UK.; Four cases of male-to-female transsexuals with HIV infection are described, showing that individuals with gender identity disorder are vulnerable to HIV infection through unsafe sexual behaviour and intravenous drug use. The various practical problems associated with carrying out major surgery on this group of individ
Heterosexual vaginal and anal intercourse amongst London heroin and cocaine users.: Int J STD AIDS. 1994 Mar-Apr;5(2):133-6. Unique Identifier : AIDSLINE MED/94305009; Strang J; Powis B; Griffiths P; Gossop M; Drug Transitions Study, National Addiction Centre, London, UK.; A community-derived sample of 392 heroin users and 145 cocaine users were interviewed about their drug use and sexual behaviour, with (optional) collection of saliva specimen for linked anonymous HIV/HBV testing. The heroin sample was stratified (50/50) across current treatment and non-treatment status. For cocaine us
Long distance truck drivers in India: HIV infection and their possible role in disseminating HIV into rural areas.: Int J STD AIDS. 1994 Mar-Apr;5(2):137-8. Unique Identifier : AIDSLINE MED/94305010; Singh YN; Malaviya AN; Department of Medicine, All India Institute of Medical Sciences,; New Delhi.; In this study, a large number of truck drivers were found to be having sex with the prostitutes in rural areas along the highways of India . Some were having sex with men also. HIV/AIDS awareness and condom use was poor among them. Three out of 302 truck drivers were found to be infe
The association of human papillomavirus infection with balanoposthitis: a description of five cases with proposals for treatment [see comments]: Int J STD AIDS. 1994 Mar-Apr;5(2):139-41. Unique Identifier : AIDSLINE MED/94305011; Birley HD; Luzzi GA; Walker MM; Ryait B; Taylor-Robinson D; Renton AM; Department of Genitourinary Medicine and Communicable Disease, St; Mary's Hospital Medical School, London, UK.; The features and clinical course of chronic balanitis in 5 patients are presented. In each case, histological examination of a cutaneous biopsy sample showed pronounced features of human papillomavirus (HPV) infection. In addition, HPV DNA was demonstrated in each biopsy specimen by a polymerase chain reaction and was
Chemical burns in colposcopy; a hazard in GUM clinics?: Int J STD AIDS. 1994 Mar-Apr;5(2):142-3. Unique Identifier : AIDSLINE MED/94305012; Clarke J; De Silva PA; Department of Genitourinary Medicine, Pinderfields Hospitals NHS; Trust, Wakefield, W. Yorkshire, UK.
Group A beta haemolytic streptococcal proctitis in an HIV-positive man.: Int J STD AIDS. 1994 Mar-Apr;5(2):144-5. Unique Identifier : AIDSLINE MED/94305013; Carlin EM; Coker RJ; Shafi S; Murphy SM; Department of Genito-Urinary Medicine, Central Middlesex; Hospital, London, UK.
Missed HIV-2 infection in a bisexual man [letter]: Int J STD AIDS. 1994 Mar-Apr;5(2):155. Unique Identifier : AIDSLINE MED/94305016; Nandwani R; Shanson D; Coleman JC
Concurrent partnerships could cause AIDS epidemics: Thailand's point of view [letter; comment]: Int J STD AIDS. 1994 Mar-Apr;5(2):155-6. Unique Identifier : AIDSLINE MED/94305017; Phanuphak P
HIV infection in the Caribbean [editorial]: Int J STD AIDS. 1994 Mar-Apr;5(2):79-89. Unique Identifier : AIDSLINE MED/94305018; Wheeler VW; Radcliffe KW; The Caribbean is a multi-ethnic region with many different cultural differences. The majority of the population is of African descent, but there are also other ethnic groups present such as Indians, Chinese, Syrians and Europeans. The Caribbean region is influenced by countries such as the USA, Great Britain,
Genitourinary medicine and the Read Codes Clinical Terms Project--a medical language for the future. Genitourinary Medicine Specialty Working Group (GUM SWG) [editorial]: Int J STD AIDS. 1994 Mar-Apr;5(2):90-2. Unique Identifier : AIDSLINE MED/94305019; Shen RN; Band B; Bingham JS; FitzGerald M; Johnson A; Pattman RS; Brown P; Barlow D
The national STD surveillance system in Italy: results of the first year of activity. STD Surveillance Working Group.: Int J STD AIDS. 1994 Mar-Apr;5(2):93-100. Unique Identifier : AIDSLINE MED/94305020; Suligoi B; Giuliani M; Binkin N; National AIDS Centre, Istituto Superiore di Sanita, Rome, Italy.; A prospective STD surveillance system was developed in Italy in 1990. Newly diagnosed cases of sexually transmitted disease (STD) are reported by a network of 45 sentinel STD clinics throughout the country. A total of 10,253 patients were reported between September 1990 and December
Emotional exhaustion and distress among nurses: how important are AIDS-care specific factors?: J Assoc Nurses AIDS Care. 1994 Mar-Apr;5(2):11-9. Unique Identifier : AIDSLINE MED/94305111; van Servellen G; Leake B; School of Nursing, Los Angeles.; This study describes distress symptomatology and levels of job-related exhaustion in a sample of 153 hospital nurses currently caring for AIDS patients. While the level of emotional exhaustion in the sample was not alarmingly high, these nurses did report symptoms of distress. Levels of emotional exhaustion were relat
Research priorities for psychosocial aspects of nursing care in HIV disease.: J Assoc Nurses AIDS Care. 1994 Mar-Apr;5(2):21-6. Unique Identifier : AIDSLINE MED/94305112; McCain NL; Zeller J; Department of Medical Nursing, Rush-Presbyterian-St. Luke's; Medical Center, Chicago, IL.; The complex biopsychosocial aspects of nursing care for persons infected with the human immunodeficiency virus (HIV) present formidable challenges for nursing research. Suggestions for clinical nursing research related to physiological aspects of HIV care recently were addressed by Zeller, Swanson, and Cohen (1993). T
Home healthcare needs of adults living with HIV disease/AIDS in New York City.: J Assoc Nurses AIDS Care. 1994 Mar-Apr;5(2):33-40. Unique Identifier : AIDSLINE MED/94305114; Hurley PM; Ungvarski PJ; Rutgers, State University of New Jersey College of Nursing,; Newark.; The authors primary purpose was to identify home healthcare needs of adults (N = 244) living with HIV disease/AIDS. The study followed a retrospective chart review of a stratified random sample of cases discharged during 1991 from a certified home health agency (CHHA) in New York City. Frequently observed signs and s
Administration of aerosol pentamidine: a program design.: J Assoc Nurses AIDS Care. 1994 Mar-Apr;5(2):41-8. Unique Identifier : AIDSLINE MED/94305115; O'Hara CM; Anton WR; Gormley FX; Brazell C; HIV/AIDS Programs, University of Washington Medical Center,; Seattle.; Aerosol pentamidine (AP) is an FDA-approved prophylaxis against pneumocystis carinii pneumonia (PCP) in HIV-infected individuals who have a CD4+ lymphocyte count less than 200/mm3, constitutional symptoms, or a previous history of the pneumonia. The University of Washington Medical Center, a 450-bed tertiary care cent
The myth of confidentiality [editorial] [see comments]: J Assoc Nurses AIDS Care. 1994 Mar-Apr;5(2):9-10. Unique Identifier : AIDSLINE MED/94305116; Kalinoski J
The evolution of tuberculosis infection among schoolchildren in Barcelona and the HIV epidemic.: Tuber Lung Dis. 1994 Apr;75(2):105-9. Unique Identifier : AIDSLINE MED/94305145; Villalbi JR; Cayla JA; Iglesias B; Ferrer A; Casanas P; Institut Municipal de la Salut, Barcelona City Health Department,; Spain.; SETTING: First grade students in primary schools in the city of Barcelona, Spain . OBJECTIVE: To estimate the prevalence of tuberculin reaction and sources of infection; to analyse trends in comparison with previous data. DESIGN: Tuberculin screening of first grade schoolchildren (19
Human immunodeficiency virus type-1 infection in Zambian children with tuberculosis: changing seroprevalence and evaluation of a thioacetazone-free regimen.: Tuber Lung Dis. 1994 Apr;75(2):110-5. Unique Identifier : AIDSLINE MED/94305146; Luo C; Chintu C; Bhat G; Raviglione M; Diwan V; DuPont HL; Zumla A; Department of Paediatrics, University Teaching Hospital, Lusaka,; Zambia.; SETTING: This study was conducted at the Department of Paediatrics and Child Health, University Teaching Hospital (UTH), in Lusaka, Zambia . OBJECTIVES: To monitor the seroprevalence of HIV type-1 in children with tuberculosis and to evaluate the response to anti-tuberculosis therap
The epidemiological evidence for an association between extrapulmonary tuberculosis and AIDS in Colombia [letter]: Tuber Lung Dis. 1994 Apr;75(2):160-1. Unique Identifier : AIDSLINE MED/94305159; Guerrero MI; Franco CI; de la Hoz F
Extrapulmonary tuberculosis and pulmonary tuberculosis are AIDS case definition criteria [letter; comment]: Tuber Lung Dis. 1994 Apr;75(2):161-2. Unique Identifier : AIDSLINE MED/94305160; Sahoo RC; Pai TM
Tuberculosis preventive therapy in HIV-infected individuals. A joint statement of the International Union Against Tuberculosis and Lung Disease (IUATLD) and the Global Programme on AIDS and the Tuberculosis Programme of the World Health Organization (WHO).: Tuber Lung Dis. 1994 Apr;75(2):96-8. Unique Identifier : AIDSLINE MED/94305164
Structure-based design of symmetric inhibitors of HIV-1 protease.: Arch Virol Suppl. 1994;9:19-29. Unique Identifier : AIDSLINE MED/94305396; Erickson J; Kempf D; Structural Biochemistry Program, Frederick Biomedical; Supercomputing Center, National Cancer Institute, Frederick; Cancer Research and Development Center, Maryland.; HIV-1, the causative agent of AIDS, encodes a protease that processes the viral polyproteins into the structural proteins and replicative enzymes found in mature virions. Protease activity has been shown to be essential for the proper assembly and maturation of fully infectious HIV-1. Thus, the HIV-1 protease (HIV PR)
Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives.: Pharm World Sci. 1994 Apr 15;16(2):113-26. Unique Identifier : AIDSLINE MED/94305498; Balzarini J; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.; Unlike herpes viruses, human immunodeficiency virus and other retroviruses do not encode specific enzymes required for the metabolism of the purine or pyrimidine nucleotides to their corresponding 5 -triphosphates. Therefore, 2 ,3 -dideoxynucleosides and acyclic nucleoside phosphonates must be phosphorylated and metab
Lymphoproliferative disorders and other tumors complicating immunodeficiencies.: Immunodeficiency. 1994;5(2):91-112. Unique Identifier : AIDSLINE MED/94305533; Filipovich AH; Mathur A; Kamat D; Kersey JH; Shapiro RS; Immunodeficiency Cancer Registry, University of Minnesota,; Minneapolis.; Lymphoproliferative disorders and selected carcinomas which occur as complications of primary or secondary immunodeficiencies are frequently fatal. The incidence rates of these cancers vary from 1% to as high as 25% among specific groups of persons with primary (genetically-determined) immunodeficiencies as well as ac
[Evaluation of risks of HIV transmission during medically assisted reproduction]: Contracept Fertil Sex. 1994 May;22(5):293-7. Unique Identifier : AIDSLINE MED/94305547; Bongain A; Isnard V; Daoudi K; Lange AC; Meynol F; Gillet JY; Departement de gynecologie-obstetrique et de medecine de la; reproduction, Centre hospitalo-universitaire de Nice-Sophia; Antipolis, Hopital Saint-Roch.; HIV transmission risks were specified during infertility treatment. An investigation was performed by gynecologists who work in IVF. Most of gynecologist refuse to treat infertility in these cases.
Oral medicine.: Curr Opin Periodontol. 1994;:54-63. Unique Identifier : AIDSLINE MED/94305644; Bissell TA; Doppalapudi VA; Department of Periodontology, Harvard School of Dental Medicine,; Boston, MA 02115.; The practice of dentistry requires an understanding of medical illnesses and the implications of treatment on the oral environment. Periodic review enables the practitioner to anticipate patient needs and to interact competently with other medical care providers. Presented in this review are recent advances in underst
AIDS hot lines and information agencies. The consistency of their information.: Arch Fam Med. 1994 May;3(5):429-36. Unique Identifier : AIDSLINE MED/94305685; Baxter JD; Gluckman SJ; Department of Medicine, Cooper Hospital/University Medical; Center, UMDNJ-Robert Wood Johnson Medical School, Camden.; OBJECTIVES: To determine the consistency of responses given by acquired immunodeficiency syndrome (AIDS) hot lines and AIDS information agencies to a standard set of questions related to human immunodeficiency virus (HIV) infection and to investigate the training of workers in these telephone information agencies. DES
Down-regulation of membrane immunoglobulin-associated proteins, MB-1, B29 and Lyn, in AIDS-lymphomas and related conditions.: Virchows Arch. 1994;424(5):553-61. Unique Identifier : AIDSLINE MED/94305722; Mori S; Takanashi M; Shiota M; Choi SH; Yamanashi Y; Watanabe T; Koike M; Department of Pathology, University of Tokyo, Japan.; B-lymphocytes infected with Epstein-Barr virus (EBV) can proliferate in immunocompromised hosts to form lymphomas (MLs). Similar MLs are produced in mice with severe combined immune deficiency (SCID) by transfusion of human lymphocytes infected with EBV (SCID-EBV-positive BML). Mb-1 and B29 are recently found transmem
The in vivo expression of cytokine genes in humans.: J Lipid Mediat Cell Signal. 1994 Feb;9(1):37-41. Unique Identifier : AIDSLINE MED/94305939; Galanaud P; Unite d'Immunopathologie et Immunologie Virale de l'INSERM; (Unite 131), l'Association Claude Bernard, Universite de; Paris-Sud, Hopital Antoine Beclere, Clamart, France.; We used in situ hybridization to study the expression of interleukin genes in sarcoidosis and in persistent generalized lymphadenopathy of HIV disease. In both cases, we found a dramatic over-expression of the interferon-gamma (IFN-gamma) gene as compared to that of the interleukin-2 (
[Immune status of hemophilia patients treated with blood preparations: laboratory and clinical assessment (review of the literature)]: Klin Lab Diagn. 1994;(1):3-5. Unique Identifier : AIDSLINE MED/94305954; Rudenko VP; Loginskii VE; Kachorovskii BV
CT of primary colonic lymphoma.: Clin Imaging. 1994 Apr-Jun;18(2):131-41. Unique Identifier : AIDSLINE MED/94306283; Wyatt SH; Fishman EK; Hruban RH; Siegelman SS; Russell H. Morgan Department of Radiology and Radiological; Science, Johns Hopkins Medical Institutions, Baltimore, Maryland.; The article presents the computed tomography (CT) findings in 15 patients with histopathologically proven primary lymphoma of the colorectum. CT is invaluable for the characterization of primary colonic lymphomas and for definition of tumor invasion and spread. The lymphomas in our series were categorized according to
Cerebral glial tumors and human immunodeficiency virus-1 infection. More than a coincidental association.: Cancer. 1994 Jul 15;74(2):686-92. Unique Identifier : AIDSLINE MED/94306330; Moulignier A; Mikol J; Pialoux G; Eliaszewicz M; Thurel C; Thiebaut JB; Hopital Tenon, Service de Neurologie, Paris, France.; BACKGROUND. The authors describe the clinical and morphologic patterns in four patients with acquired immune deficiency syndrome (AIDS) who developed intracranial glial tumors. METHODS. This retrospective study reports 70 patients at various stages of human immunodeficiency virus-1 (HIV-1) infection who underwent ster
Synthesis and antiviral activity of 3'-azido-3'-deoxythymidine triphosphate distearoylglycerol: a novel phospholipid conjugate of the anti-HIV agent AZT.: Chem Phys Lipids. 1994 Apr 19;70(2):213-22. Unique Identifier : AIDSLINE MED/94306606; van Wijk GM; Hostetler KY; Kroneman E; Richman DD; Sridhar CN; Kumar R; van den Bosch H; Centre for Biomembranes and Lipid Enzymology, Utrecht University,; Netherlands.; Phospholipid conjugates of 3 -azido-3 -deoxythymidine ( AZT ) show activity against the human immunodeficiency virus (HIV) in vitro. In a previous report (K.Y. Hostetler, L.M. Stuhmiller, B.H.M. Lenting, H. van den Bosch and D.D. Richman (1991), J. Biol
The difficulty in diagnosis of cutaneous herpes simplex virus infection in patients with AIDS.: Clin Exp Dermatol. 1994 May;19(3):224-6. Unique Identifier : AIDSLINE MED/94306710; Langtry JA; Ostlere LS; Hawkins DA; Staughton RC; Department of Dermatology, Royal Infirmary, Sunderland, UK.; Three patients with AIDS are described with atypical manifestations of cutaneous herpes simplex virus infection. This infection should be considered in the immunosuppressed patient with persistent or bizarre cutaneous ulceration despite negative virological cultures, and in the acutely ill patient with a generalized r
Cytotoxic T lymphocyte activity and CD8 subpopulations in children at risk of HIV infection.: Clin Exp Immunol. 1994 Jul;97(1):61-7. Unique Identifier : AIDSLINE MED/94306754; Aldhous MC; Watret KC; Mok JY; Bird AG; Froebel KS; University Department of Medicine, Royal Infirmary, Edinburgh,; UK.; HIV-specific cytotoxic T lymphocytes (CTL) are thought to play a major role in viral control in HIV-infected adults. Changes in the relative proportions of CD8 lymphocyte subpopulations are also thought to be associated with disease progression. Less is known about the relative effectiveness of CTL against different H
Mycobacterium avium infection in HIV-1-infected subjects increases monokine secretion and is associated with enhanced viral load and diminished immune response to viral antigens.: Clin Exp Immunol. 1994 Jul;97(1):76-82. Unique Identifier : AIDSLINE MED/94306756; Denis M; Ghadirian E; Pulmonary Research Unit, Faculty of Medicine, University of; Sherbrooke, Canada.; The complex interaction between HIV-1 infection and Mycobacterium avium was studied. Viral burden was assessed, as well as immune response to HIV-1 in the context of Myco. avium infections. We also examined serum cytokine levels and cytokine release by blood mononuclear cells in HIV-1-infected subjects, infected or no
Nitric oxide synthesis in patients with advanced HIV infection.: Clin Exp Immunol. 1994 Jul;97(1):83-6. Unique Identifier : AIDSLINE MED/94306757; Evans TG; Rasmussen K; Wiebke G; Hibbs JB Jr; Infectious Disease Section (111L), Salem VAMC, VA 24153.; The discovery that humans produce nitric oxide and that this molecule plays an important role in cell communication, host resistance to infection, and perhaps in host defence to neoplastic disease, has created much interest in further research on its function in the body. A cytokine-inducible high output L-arginine/ni
Intravenous immune globulin in primary immunodeficiency.: Clin Exp Immunol. 1994 Jul;97 Suppl 1:11-5. Unique Identifier : AIDSLINE MED/94306760; Haeney M; Hope Hospital, University of Manchester School of Medicine,; Salford, UK.; The development of safe and effective intravenous preparations of immune globulin (IVIG) represents a major advance in the treatment of patients with severe antibody deficiencies. Such therapy is expensive, few trials have been performed to compare one type of IVIG preparation with another under equivalent conditions,
Does intravenous immune globulin have a role in HIV-infected patients?: Clin Exp Immunol. 1994 Jul;97 Suppl 1:59-67. Unique Identifier : AIDSLINE MED/94306770; Yap PL; Edinburgh & South East Scotland Blood Transfusion Service, UK.; The main immunological abnormality in human immunodeficiency virus (HIV)-infected patients, and particularly those with the acquired immune deficiency syndrome (AIDS), is a deficiency in cellular immunity. However, symptomatic HIV-infected children also have evidence of deficiency of specific antibody synthesis, and i
[Examination on the level of IL-2, the percentages of the cells with IL-2 receptor and the ratios of T4T8 of the patients with periodontitis]: Chung Hua Kou Chiang Hsueh Tsa Chih. 1993 Nov;28(6):356-8. Unique Identifier : AIDSLINE MED/94306992; Chen LL
Flow cytometric analysis of natural killer cell function as a clinical assay.: Cytometry. 1994 May 1;16(1):59-68. Unique Identifier : AIDSLINE MED/94307086; Hatam L; Schuval S; Bonagura VR; Department of Pediatrics, Schneider Children's Hospital, Long; Island Jewish Medical Center, New Hyde Park, NY 11042.; The 51Cr release assay has been the method of choice in analyzing natural killer cell (NK) function. Previous FCM cytotoxicity assays of NK activity have had numerous disadvantages that discouraged clinicians from attempting to evaluate NK function by flow cytometry. We demonstrate the effectiveness of using PKH-26, a
HIV-transmission knowledge in drug users from outpatient facilities in Spain. A national survey.: Drug Alcohol Depend. 1994 Feb;34(3):181-90. Unique Identifier : AIDSLINE MED/94307109; Lopez R; Bravo MJ; Barrio G; Lardelli P; Bueno A; de la Fuente L; Department of Public Health, School of Medicine, University of; Granada, Spain.; Knowledge of AIDS and its transmission was studied in patients undergoing drug-dependence treatment for opiates and/or cocaine. The study area included all of Spain and was carried out via a questionnaire assessing information about risk practices, HIV serostatus, etc, and 13 true o
Prevalence, symptoms and correlates of antisocial personality disorder among methadone maintenance clients.: Drug Alcohol Depend. 1994 Feb;34(3):253-7. Unique Identifier : AIDSLINE MED/94307118; Darke S; Hall W; Swift W; National Drug and Alcohol Research Centre, University of New; South Wales, Kensington, Australia.; A sample of 222 methadone maintenance (MM) clients were tested for a diagnosis of antisocial personality disorder (ASPD). The majority (60.8%) of clients qualified for a lifetime diagnosis of ASPD, 25.7% received a current diagnosis of ASPD, and a conduct disorder of childhood was diagnosed for 68.5% of subjects. The
Kenyan university students' views on AIDS.: East Afr Med J. 1993 Nov;70(11):713-6. Unique Identifier : AIDSLINE MED/94307128; Sindiga I; Lukhando M; Department of Tourism, Faculty of Health Sciences, Moi; University, Eldoret, Kenya.; In view of the rapidly increasing number of AIDS cases reported in Kenya since 1984, a survey was conducted among Kenyatta University undergraduate students during October and November 1988 to gauge their knowledge, attitudes and practices with regard to the disease. A random sample
The impact of AIDS in a rural Ugandan community.: East Afr Med J. 1993 Nov;70(11):725-9. Unique Identifier : AIDSLINE MED/94307131; Konde-Lule JK; Sebina AJ; Institute of Public Health, Makerere University, Kampala, Uganda.; Three AIDS related surveys have been conducted on a community based cohort in the Kasangati defined area, Uganda , during 1987, 1990 and 1992. The 1987 baseline survey recruited 1990 adults, and in addition to assessing levels of knowledge, attitudes and practices, HIV serology was
A family of selective immunodeficiency with normal immunoglobulins: possible autosomal dominant inheritance.: Eur J Pediatr. 1994 May;153(5):328-32. Unique Identifier : AIDSLINE MED/94307290; Higuchi S; Awata H; Nunoi H; Tsuchiya H; Naoe H; Igarashi H; Matsuda I; Department of Paediatrics, Kumamoto University Medical School,; Japan.; We report here our findings in two Japanese siblings who experienced recurrent bacterial and viral infections since early infancy. Recent symptoms included diarrhoea, conjunctivitis, rashes, headache, sore throat, joint pain, vomiting and vertigo, all similar to those seen in toxic shock syndrome, except for shock. Th
Human T lymphotropic virus type I associated myelopathy and myasthenia gravis: a possible association?: Eur Neurol. 1994;34(3):158-61. Unique Identifier : AIDSLINE MED/94307313; Fukui T; Sugita K; Ichikawa H; Negishi A; Kasai H; Tsukagoshi H; Department of Neurology, Showa University School of Medicine,; Tokyo, Japan.; We report the first known patient with human T lymphotropic virus type I (HTLV-I) associated myelopathy (HAM) and myasthenia gravis (MG). A 50-year-old woman developed fluctuating muscle weakness with easy fatigability, transient bilateral blepharoptosis and double vision. Spastic paraparesis complicated these symptom
Comparative contraceptive efficacy of the female condom and other barrier methods.: Fam Plann Perspect. 1994 Mar-Apr;26(2):66-72. Unique Identifier : AIDSLINE MED/94307358; Trussell J; Sturgen K; Strickler J; Dominik R; Woodrow Wilson School of Public and International Affairs,; Princeton University, N.J.; Because the research design for the clinical trial establishing the contraceptive efficacy of the female condom--a six-month life-table probability of failure of 15% (12% in the United States vs. 22% in Latin America)--did not include randomization with another method of contraception,
Luffin-S--a small novel ribosome-inactivating protein from Luffa cylindrica. Characterization and mechanism studies.: FEBS Lett. 1994 Jun 27;347(2-3):257-60. Unique Identifier : AIDSLINE MED/94307395; Gao W; Ling J; Zhong X; Liu W; Zhang R; Yang H; Cao H; Zhang Z; Shanghai Institute of Biochemistry, Academia Sinica, P.R. China.; We purified and characterized a novel RIP (ribosome inactivating protein), Luffin-S from the seeds of Luffa cylindrica. Different from Luffin-A and B, which are RNA N-glycosidases with molecular weights of 27 and 28 kDa, respectively, Luffin-S has an M.W. of only approx. 10 kDa, much smaller than any other RIPs so far
Antisense oligonucleotide complementary to endogenous retroviral MCF env gene inhibits both BFU-E and CFU-S colony formation in mice.: FEBS Lett. 1994 Jul 11;348(2):197-200. Unique Identifier : AIDSLINE MED/94307424; Chernukhin IV; Khaldoyanidi SK; Dikovskaya DV; Svinarchuk FP; Vlasov VV; Gaidul KV; Institute of Clinical Immunology, Novosibirsk, Russian; Federation.; A possible biologic activity of endogenously expressed env sequence of retroviral mink cell focus-forming virus (MCF) genome for hematopoietic colony formation was studied in mice. Antisense 20-mer complementary to MCF env sequence was used to detect the result of blockage of this gene translation on the potency of ma
[The clinical and laboratory characteristics of mature (postthymic) T-cell malignant neoplasms]: Gematol Transfuziol. 1993 May;38(5):3-6. Unique Identifier : AIDSLINE MED/94307564; Matutes E; Catovsky D
Reducing HIV risk behavior among injection drug users: effect of methadone maintenance treatment on number of sex partners.: Int J Addict. 1994 Apr;29(6):741-57. Unique Identifier : AIDSLINE MED/94307810; Longshore D; Hsieh SC; Anglin MD; Drug Abuse Research Center, University of California, Los Angeles; 90024.; Some studies have found that sex-related HIV risk behavior is less common among drug users in treatment than among users not in treatment; other studies have found no such relationship. However, past studies have not controlled for drug-user background characteristics that might confound the relationship between treat
Man-made medicine and women's health: the biopolitics of sex/gender and race/ethnicity.: Int J Health Serv. 1994;24(2):265-83. Unique Identifier : AIDSLINE MED/94307820; Krieger N; Fee E; Division of Research, Kaiser Foundation Research Institute,; Oakland, CA 94611.; National vital statistics in the United States present data in terms of race, sex, and age, treated as biological variables. Some races are clearly of more interest than others: data are usually available for whites and blacks, and increasingly for Hispanics, but seldom for Native Amer
Nuclear fallout, low birthweight, and immune deficiency.: Int J Health Serv. 1994;24(2):311-35. Unique Identifier : AIDSLINE MED/94307822; Gould JM; Sternglass EJ; Radiation and Public Health Project, New York, NY 10024.; An investigation of the mortality rates of young adults born in the postwar period of large-scale atmospheric nuclear testing (1945-1965) in the United States and other western industrial nations reveals an increasingly anomalous rise in mortality from its previous secular decline. Beg
Use of a home-care computer network by persons with AIDS.: Int J Technol Assess Health Care. 1994 Spring;10(2):258-72. Unique Identifier : AIDSLINE MED/94307832; Brennan PF; Ripich S; Case Western Reserve University.; Computer networks serve as convenient, efficient, and enduring vehicles for delivering nursing services to patients at home. The ComputerLink, a specialized computer network, provided nurse-supervised information, decision support, and communication services to home-dwelling persons living with AIDS (PWAs). During a 2
WHO: new UN programme on HIV/AIDS [news]: Int Nurs Rev. 1994 Mar-Apr;41(2):39. Unique Identifier : AIDSLINE MED/94307840
Community responses to AIDS.: Int Nurs Rev. 1994 Mar-Apr;41(2):57-60. Unique Identifier : AIDSLINE MED/94307844; Anderson S; Health Care Support Unit, Division of Technical Cooperation,; World Health Organization, Geneva, Switzerland.; As it becomes clear that national actions alone will not handle the AIDS epidemic, more responsibility is being given to communities, whose characteristics lend themselves to coping with the complicated aspects of the AIDS epidemic. But community members cannot handle the AIDS-related problems alone. They need help in
A new look at HIV transmission from seropositive mothers to their infants: the facts beyond serology.: Isr J Med Sci. 1994 May-Jun;30(5-6):364-8. Unique Identifier : AIDSLINE MED/94307914; Jehuda-Cohen T; Pediatric Research Unit, Rappaport Faculty of Medicine,; Technion-Israel Institute of Technology, Haifa, Israel.; Once the curtain of maternal antibodies is removed (12-18 months) only a fraction of the infants are seropositive. Some babies from whom virus has been isolated or detected in their cells subsequently become seronegative. What does the negative serology of these children really tell us about exposure to HIV? It is sug
In utero diagnosis of congenital infections by direct fetal sampling.: Isr J Med Sci. 1994 May-Jun;30(5-6):414-20. Unique Identifier : AIDSLINE MED/94307927; Valente P; Sever JL; Laboratory of Central Nervous System Studies, NINDS, NIH,; Bethesda, MD 20892.; Counseling for infections during pregnancy has traditionally focused on the clinical and laboratory findings of infection in the mother and the estimated risk of fetal damage associated with possible transmission of infection to the child. Now, with the use of techniques for fetal sampling, it is possible to diagnose
Early diagnosis and immunologic changes in HIV-1 infected pregnant women and their children.: Isr J Med Sci. 1994 May-Jun;30(5-6):421-30. Unique Identifier : AIDSLINE MED/94307928; Valente P; Sever JL; Laboratory of Central Nervous System Studies, NINDS, NIH,; Bethesda, MD 20892.; The diagnosis of HIV infection in pregnant women is usually based on the detection of HIV-specific antibodies. These tests become positive a few weeks to months after infection. In the United States , it is recommended that tests be offered to all women and encouraged where the rate of
Task force on AIDS.: J Ark Med Soc. 1994 Mar;90(10):496-7. Unique Identifier : AIDSLINE MED/94308016
The secreted tumor-associated antigen 90K is a potent immune stimulator.: J Biol Chem. 1994 Jul 15;269(28):18401-7. Unique Identifier : AIDSLINE GENBANK/X79089; Ullrich A; Sures I; D'Egidio M; Jallal B; Powell TJ; Herbst R; Dreps A; Azam M; Rubinstein M; Natoli C; et al; Department of Molecular Biology, Max-Planck-Institut fur; Biochemie, Martinsried, Federal Republic of Germany.; Immunization of mice with conditioned media from human breast cancer cells yielded the monoclonal antibody SP-2, which recognized an antigen of approximately 90-95 kDa. This protein, designated 90K, was found to be present in the serum of healthy individuals and at elevated levels in the serum of subpopulations of pat
Cleavage at the amino and carboxyl termini of Alzheimer's amyloid-beta by cathepsin D.: J Biol Chem. 1994 Jul 15;269(28):18422-8. Unique Identifier : AIDSLINE MED/94308073; Ladror US; Snyder SW; Wang GT; Holzman TF; Krafft GA; Abbott Laboratories, Abbott Park, Illinois 60064.; Amyloid beta (A beta) is a 39-43-residue protein that originates from proteolysis of the beta-protein precursor (beta PP) and accumulates in senile plaques in brains of Alzheimer s disease (AD) patients. Mutant beta PP, which incorporates an AD-causing double mutation at positions 687-688, has been shown to enhance A
The use of methotrexate for treatment of psoriasis in patients with HIV infection.: J Am Acad Dermatol. 1994 Aug;31(2 Pt 2):372-5. Unique Identifier : AIDSLINE MED/94308359; Maurer TA; Zackheim HS; Tuffanelli L; Berger TG; Department of Dermatology, University of San Francisco, CA.; The use of methotrexate (MTX) has been contraindicated for treatment of severe psoriasis in HIV infection on the basis of six previously reported cases in which MTX appeared to potentiate opportunistic infections and accelerate HIV disease. We describe three HIV-infected patients who were given MTX for severe psoriati
Publication lists AIDS drugs in development [news]: Indiana Med. 1994 May-Jun;87(3):249. Unique Identifier : AIDSLINE MED/94308522
Detection of antiphospholipid antibodies by immunostaining on thin layer chromatography plates.: J Immunol Methods. 1994 Jul 12;173(1):49-54. Unique Identifier : AIDSLINE MED/94308563; Sorice M; Griggi T; Circella A; Garofalo T; d'Agostino F; Pittoni V; Pontieri GM; Lenti L; Valesini G; Dipartimento di Medicina Sperimentale, Universita La Sapienza,; Roma, Italy.; There is increasing interest in the role of antiphospholipid antibodies in the so-called antiphospholipid antibody syndrome (APS). The two major methods currently employed for detecting the autoantibodies are the solid phase ELISA and the LAI test (inhibition of phospholipid dependent coagulation assay). In our stud
Acyclovir. Is the honeymoon coming to an end? [editorial]: J Infect. 1994 Mar;28(2):121-9. Unique Identifier : AIDSLINE MED/94308569; Welsby PD
Epidemic of herpes zoster following HIV epidemic in Manipur, India.: J Infect. 1994 Mar;28(2):167-73. Unique Identifier : AIDSLINE MED/94308574; Panda S; Sarkar S; Mandal BK; Singh TB; Singh KL; Mitra DK; Sarkar K; Tripathy SP; Deb BC; ICMR Unit for Research on AIDS in north eastern states of India,; Calcutta.; Since 1989, injecting drug use (IDU) related HIV infection has affected thousands of young adults in Manipur, a north eastern state of India bordering Myanmar following a similar kind of epidemic in adjoining countries like
Occupational risk and precautions related to HIV infection among dentists in the Lothian region of Scotland.: J Infect. 1994 Mar;28(2):209-22. Unique Identifier : AIDSLINE MED/94308580; Gore SM; Felix DH; Bird AG; Wray D; MRC Biostatistics Unit, Institute of Public Health, Cambridge,; U.K.; This retrospective study used a postal questionnaire to measure occupational risks and to assess infection control procedures among 310 dental practitioners. The study comprised general dental practices in the Lothian region of Scotland, Lothian Health Board Community Dental Service and Edinburgh Dental Hospital. Alto
Respiratory cryptosporidiosis as a presenting feature of AIDS [letter]: J Infect. 1994 Mar;28(2):227-9. Unique Identifier : AIDSLINE MED/94308582; Mifsud AJ; Bell D; Shafi MS
Dynamics of emergence [see comments]: J Infect Dis. 1994 Aug;170(2):265-71. Unique Identifier : AIDSLINE MED/94308587; Krause RM; Fogarty International Center, National Institutes of Health,; Bethesda, MD 20892.; I have touched briefly here on the complex matrix of social, economic, political, and ecologic factors that have played a major role in the emergence of microbial diseases. But beyond these factors that contribute to the emergence of new infectious diseases, we must also recognize changes in microbial agents, human po
Pathogenesis of pediatric human immunodeficiency virus type 1 infection.: J Infect Dis. 1994 Aug;170(2):286-92. Unique Identifier : AIDSLINE MED/94308591; Wilfert CM; Wilson C; Luzuriaga K; Epstein L; Duke University Medical Center, Durham, NC 27710.; This discussion of the pathogenesis of infant human immunodeficiency virus (HIV) type 1 infection emphasizes features unique to pediatric disease and provides general insights into HIV illness in all populations. Therapies designed to interrupt transmission of HIV can be most efficiently addressed through studies of m
A longitudinal study of cytomegalovirus infection in human immunodeficiency virus type 1-seropositive homosexual men: molecular epidemiology and association with disease progression.: J Infect Dis. 1994 Aug;170(2):293-8. Unique Identifier : AIDSLINE MED/94308592; Leach CT; Detels R; Hennessey K; Liu Z; Visscher BR; Dudley JP; Cherry JD; UCLA School of Public Health.; Cytomegalovirus ( CMV ) isolates from 234 asymptomatic human immunodeficiency type 1 (HIV-1)-positive men were analyzed for molecular relatedness using junctional hybridization. Of isolates shed simultaneously at two or more body sites, 36% from 22 men were differ
Intestinal mucosal immunoglobulins during human immunodeficiency virus type 1 infection.: J Infect Dis. 1994 Aug;170(2):299-307. Unique Identifier : AIDSLINE MED/94308593; Janoff EN; Jackson S; Wahl SM; Thomas K; Peterman JH; Smith PD; Department of Medicine, VA Medical Center, Minneapolis, MN 55417.; In intestinal fluid samples from 39 human immunodeficiency virus type 1 (HIV-1)-infected patients, IgA and IgG levels were equivalent, whereas in 10 controls, IgA levels were significantly higher than those of IgG (P
Association between anti-human immunodeficiency virus type 1 (HIV-1) antibody-dependent cellular cytotoxicity antibody titers at birth and vertical transmission of HIV-1.: J Infect Dis. 1994 Aug;170(2):308-12. Unique Identifier : AIDSLINE MED/94308594; Jenkins M; Landers D; Williams-Herman D; Wara D; Viscarello RR; Hammill HA; Kline MW; Shearer WT; Charlebois ED; Kohl S; Department of Pediatrics, University of California, San; Francisco.; Because vertical transmission of human immunodeficiency virus type 1 (HIV-1) from mother to infant occurs in only 15%-35% of possible opportunities, natural immune defenses of the mother, fetus, or neonate may be protective against infection. The relation between antibody-dependent cellular cytotoxicity (ADCC) antibod
Sensitive detection and early prognostic significance of p24 antigen in heat-denatured plasma of human immunodeficiency virus type 1-infected infants. Swiss Neonatal HIV Study Group.: J Infect Dis. 1994 Aug;170(2):318-24. Unique Identifier : AIDSLINE MED/94308596; Schupbach J; Boni J; Tomasik Z; Jendis J; Seger R; Kind C; Swiss National Center for Retroviruses, University of Zurich.; Immune complex formation causes underdetection of p24 antigen in human immunodeficiency virus (HIV) infection. Briefly boiling diluted plasma releases all complexed antigen, which can then be measured by some commercial assays. In a retrospective pediatric cohort study, the specificity of this procedure in 390 uninfec
Quantitative analysis of viral burden in tissues from adults and children with symptomatic human immunodeficiency virus type 1 infection assessed by polymerase chain reaction.: J Infect Dis. 1994 Aug;170(2):325-33. Unique Identifier : AIDSLINE MED/94308597; Sei S; Kleiner DE; Kopp JB; Chandra R; Klotman PE; Yarchoan R; Pizzo PA; Mitsuya H; Medicine Branch, National Cancer Institute, NIH, Bethesda, MD; 20892.; The amount of human immunodeficiency virus type 1 (HIV-1) in various tissues was investigated by polymerase chain reaction (PCR) in 16 patients with end-stage HIV-1 infection and 7 patients with symptomatic but less advanced disease. During postmortem study of the 16 end-stage patients, HIV-1 DNA was found most often
Demonstration of human T lymphotropic virus type I (HTLV-I)-specific T cell responses from seronegative and polymerase chain reaction-negative persons exposed to HTLV-I.: J Infect Dis. 1994 Aug;170(2):334-8. Unique Identifier : AIDSLINE MED/94308598; Nishimura M; Kermode AG; Clerici M; Shearer GM; Berzofsky JA; Uchiyama T; Wiktor SZ; Pate E; Maloney B; Manns A; et al; Neuroimmunology Branch, National Institute of Neurological; Disorders and Stroke, Bethesda, MD 20892.; Human T lymphotropic virus type I (HTLV-I) is a human retrovirus etiologically linked to adult T cell leukemia and the progressive chronic neurologic disease HTLV-I-associated myelopathy/tropical spastic paraparesis. Described is a method that measures the production of interleukin-2 from HTLV-I synthetic peptide-stim
Binding of human immunodeficiency virus type 1 to the C3b/C4b receptor CR1 (CD35) and red blood cells in the presence of envelope-specific antibodies and complement. National Institutes of Health AIDS Vaccine Clinical Trials Networks.: J Infect Dis. 1994 Aug;170(2):429-32. Unique Identifier : AIDSLINE MED/94308613; Montefiori DC; Graham BS; Zhou JY; Zhou JT; Ahearn JM; Dept. of Surgery, Duke University Medical Center, Durham, NC; 27710.; Immune complexes formed in vitro by incubating cell-free human immunodeficiency virus type 1 (HIV-1) with sera from infected or gp160-vaccinated persons, together with normal human serum as a source of complement, readily bound to K562 cells expressing recombinant human complement receptor type 1 (CR1). However, antib
Bacille Calmette-Guerin immunization in normal healthy adults.: J Infect Dis. 1994 Aug;170(2):476-9. Unique Identifier : AIDSLINE MED/94308625; Brewer MA; Edwards KM; Palmer PS; Hinson HP; Department of Pediatrics, Vanderbilt University School of; Medicine, Nashville, Tennessee.; Bacille Calmette-Guerin (BCG) vaccine was administered to 20 purified protein derivative (PPD) skin test-negative and human immunodeficiency virus serology-negative, healthy adults 18-65 years old. Local adverse reactions were monitored and intermediate-strength PPD skin test responses were evaluated 2 months and 1 ye
Pentoxifylline aggravates impairment in tumor necrosis factor-alpha secretion and increases mycobacterial load in macrophages from AIDS patients with disseminated Mycobacterium avium-intracellulare complex infection.: J Infect Dis. 1994 Aug;170(2):484-7. Unique Identifier : AIDSLINE MED/94308627; Sathe SS; Sarai A; Tsigler D; Nedunchezian D; Div. of Infectious Diseases, Brooklyn VA Medical Center, NY; 11209.; Pentoxifylline, which inhibits tumor necrosis factor-alpha (TNF alpha), decreases human immunodeficiency virus replication in peripheral blood mononuclear cells. However, TNF alpha is important in cellular defense against M. avium-intracellulare complex (MAC), a common infection in advanced AIDS. The effect of pentoxi
Transient bacteremia due to Mycobacterium avium complex in patients with AIDS.: J Infect Dis. 1994 Aug;170(2):488-93. Unique Identifier : AIDSLINE MED/94308628; Kemper CA; Havlir D; Bartok AE; Kane C; Camp B; Lane N; Deresinski SC; Department of Medicine, Santa Clara Valley Medical Center, San; Jose, CA 95128.; It is generally assumed that Mycobacterium avium complex (MAC) bacteremia, once it develops, is unremitting. On the basis of this presumption, changes in the level of mycobacteremia are used to gauge therapeutic response. In 7 (12%) of 60 patients enrolled in a prospective trial of MAC bacteremia and AIDS, bacteremia
Cryptosporidial and microsporidial infections in human immunodeficiency virus-infected patients in northeastern Brazil.: J Infect Dis. 1994 Aug;170(2):494-7. Unique Identifier : AIDSLINE MED/94308629; Wuhib T; Silva TM; Newman RD; Garcia LS; Pereira ML; Chaves CS; Wahlquist SP; Bryan RT; Guerrant RL; Sousa A de Q; et al; Division of Infectious Diseases, Johns Hopkins University School; of Medicine, Baltimore, Maryland 21205-2196.; To determine the frequency of the parasitic pathogens in human immunodeficiency virus (HIV)-infected patients in a developing world setting, 295 stool specimens were examined from 166 HIV-positive patients (49% with AIDS) at Sao Jose Hospital, Fortaleza, Brazil , from September 1990
Human immunodeficiency virus serostatus and the risk of postextraction complications.: Int J Oral Maxillofac Surg. 1994 Apr;23(2):100-3. Unique Identifier : AIDSLINE MED/94308633; Dodson TB; Perrott DH; Gongloff RK; Kaban LB; Department of Surgery, Emory University, Atlanta, GA.; Despite the increasing prevalence of human immunodeficiency virus (HIV) disease in the population and the increasing likelihood that HIV-positive (HIV+) patients may have an extraction, little is known about the risk of postoperative complications in this group. The goal of this investigation was to assess the risk of
The effect of physical organic properties on hydrophobic fields.: J Comput Aided Mol Des. 1994 Feb;8(1):41-9. Unique Identifier : AIDSLINE MED/94308823; Abraham DJ; Kellogg GE; Department of Medicinal Chemistry, Medical College of Virginia,; Virginia Commonwealth University, Richmond 23298-0540.; Physical organic structural properties of small molecules and macromolecules such as bond count, branching and proximity between multiple polar fragments contribute significantly to measured hydrophobicity (log P). These structural properties are encoded in the Rekker and Leo methods of calculating log P as structural
AIDS dementia complex.: J Palliat Care. 1994 Spring;10(1):46-50. Unique Identifier : AIDSLINE MED/94308872; Katz A; Village Clinic, Winnipeg, Manitoba.
Rheumatic diseases and AIDS--is the association real? [letter; comment]: J Rheumatol. 1994 Apr;21(4):769-70. Unique Identifier : AIDSLINE MED/94309054; Stein CM; Davis P
Three-dimensional quantitative structure-activity relationship of human immunodeficiency virus (I) protease inhibitors. 2. Predictive power using limited exploration of alternate binding modes.: J Med Chem. 1994 Jul 8;37(14):2206-15. Unique Identifier : AIDSLINE MED/94309074; Oprea TI; Waller CL; Marshall GR; Center for Molecular Design, Washington University School of; Medicine, St. Louis, Missouri 63130-4866.; NewPred, a semiautomated procedure to evaluate alternate binding modes and assist three dimensional quantitative structure-activity relationship (3D-QSAR) studies in predictive power evaluation is exemplified with a series of 30 human immunodeficiency virus 1 protease (HIV PR) inhibitors. Five comparative molecular fi
Inhibition of human immunodeficiency virus type 1 replication by phosphonoformate- and phosphonoacetate-2',3'-dideoxy-3'-thiacytidine conjugates.: J Med Chem. 1994 Jul 8;37(14):2216-23. Unique Identifier : AIDSLINE MED/94309075; Charvet AS; Camplo M; Faury P; Graciet JC; Mourier N; Chermann JC; Kraus JL; Laboratoire de Chimie Biomoleculaire, Faculte des Sciences de; Luminy, Marseille, France.; The synthesis of potential combined prodrugs where phosphonoformic acid (PFA) or phosphonoacetic acid (PAA) was attached to the 5 -O or N4 position of 2 ,3 -dideoxy-3 -thiacytidine (BCH-189) is described. The anti-HIV-1 activity of 11 analogues which included carboxylic ester or phosphoric ester linkages of PFA or PAA
Human immunodeficiency virus type 1 integrase: effect on viral replication of mutations at highly conserved residues.: J Virol. 1994 Aug;68(8):4768-75. Unique Identifier : AIDSLINE MED/94309139; Cannon PM; Wilson W; Byles E; Kingsman SM; Kingsman AJ; Department of Biochemistry, University of Oxford, United Kingdom.; Sequence comparisons of the integrase (IN) proteins from different retroviruses have identified several highly conserved residues. We have introduced mutations at 16 of these sites into the integrase gene of human immunodeficiency virus type 1 and analyzed the phenotypes of the resulting viruses. The viruses were all
The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells.: J Virol. 1994 Aug;68(8):4857-61. Unique Identifier : AIDSLINE MED/94309148; Lodge R; Gottlinger H; Gabuzda D; Cohen EA; Lemay G; Departement de Microbiologie et Immunologie, Universite de; Montreal, Quebec, Canada.; Human immunodeficiency virus type 1 (HIV-1) has been shown to exhibit a specific basolateral release in polarized epithelial cells. Previous investigators have used vaccinia virus recombinants expressing HIV proteins to demonstrate that virus release is nonpolarized in the absence of viral envelope glycoproteins. In t
Incorporation of homologous and heterologous proteins into the envelope of Moloney murine leukemia virus.: J Virol. 1994 Aug;68(8):4879-89. Unique Identifier : AIDSLINE MED/94309151; Suomalainen M; Garoff H; Department of Molecular Biology, Karolinska Institute, Novum,; Huddinge, Sweden.; The efficiencies with which homologous and heterologous proteins are incorporated into the envelope of Moloney murine leukemia virus (M-MuLV) have been analyzed by utilizing a heterologous, Semliki Forest virus-driven M-MuLV assembly system and quantitative pulse-chase assays. Homologous M-MuLV spike protein was found
Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis.: J Virol. 1994 Aug;68(8):4927-36. Unique Identifier : AIDSLINE MED/94309156; Mammano F; Ohagen A; Hoglund S; Gottlinger HG; Division of Human Retrovirology, Data-Farber Cancer Institute,; Boston, Massachusetts.; Retroviral capsid (CA) proteins contain a uniquely conserved stretch of 20 amino acids which has been named the major homology region (MHR). To examine the role of this region in human immunodeficiency virus type 1 morphogenesis and replication, four highly conserved positions in the MHR were individually altered by s
Nuclear localization of foamy virus Gag precursor protein.: J Virol. 1994 Aug;68(8):4946-54. Unique Identifier : AIDSLINE MED/94309158; Schliephake AW; Rethwilm A; Institut fur Virologie und Immunbiologie, Wurzburg, Germany.; All foamy viruses give rise to a strong nuclear staining when infected cells are reacted with sera from infected hosts. This nuclear fluorescence distinguishes foamy viruses from all other retroviruses. The experiments reported here indicate that the foamy virus Gag precursor protein is transiently located in the nucl
Differential regulation of cellular tropism and sensitivity to soluble CD4 neutralization by the envelope gp120 of human immunodeficiency virus type 1.: J Virol. 1994 Aug;68(8):4973-9. Unique Identifier : AIDSLINE MED/94309161; Stamatatos L; Werner A; Cheng-Mayer C; Cancer Research Institute, School of Medicine, University of; California, San Francisco 94143-0128.; Using recombinant and mutant viruses generated between two human immunodeficiency virus type 1 isolates that display differences in cell tropism and sensitivity to soluble CD4 neutralization, we show that these two properties of the virus are regulated by different mechanisms. Whereas there is an association between V
Characterization of human immunodeficiency virus type 1 dimeric RNA from wild-type and protease-defective virions.: J Virol. 1994 Aug;68(8):5013-8. Unique Identifier : AIDSLINE MED/94309166; Fu W; Gorelick RJ; Rein A; ABL-Basic Research Program, NCI-Frederick Cancer Research and; Development Center, Maryland 21702-1201.; We have characterized the dimeric genomic RNA in particles of both wild-type and protease (PR)-deficient human immunodeficiency virus type 1 (HIV-1). We found that the dimeric RNA isolated from PR- mutant virions has a lower mobility in nondenaturing gel electrophoresis than that from wild-type virions. It also dissoc
Direct injection of a recombinant retroviral vector induces human immunodeficiency virus-specific immune responses in mice and nonhuman primates.: J Virol. 1994 Aug;68(8):5036-44. Unique Identifier : AIDSLINE MED/94309169; Irwin MJ; Laube LS; Lee V; Austin M; Chada S; Anderson CG; Townsend K; Jolly DJ; Warner JF; Department of Immunobiology, Viagene, Inc., San Diego, California; 92121.; The cytotoxic T-lymphocyte (CTL) response plays an important role in controlling the severity and duration of viral infections. Immunization by direct in vivo administration of retroviral vector particles represents an efficient means of introducing and expressing genes and, subsequently, the proteins they encode in v
Evaluation of human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T-lymphocyte responses utilizing B-lymphoblastoid cell lines transduced with the CD4 gene and infected with HIV-1.: J Virol. 1994 Aug;68(8):5074-83. Unique Identifier : AIDSLINE MED/94309173; McElrath MJ; Rabin M; Hoffman M; Klucking S; Garcia JV; Greenberg PD; Department of Medicine, University of Washington School of; Medicine, Seattle.; Analysis of major histocompatibility complex-restricted cytotoxic T lymphocytes (CTL) capable of killing human immunodeficiency virus type 1 (HIV-1)-infected targets is essential for elucidating the basis for HIV-1 disease progression and the potential efficacy of candidate vaccines. The use of primary CD4+ T cells wi
Development of the anti-gp120 antibody response during seroconversion to human immunodeficiency virus type 1.: J Virol. 1994 Aug;68(8):5142-55. Unique Identifier : AIDSLINE MED/94309181; Moore JP; Cao Y; Ho DD; Koup RA; Aaron Diamond AIDS Research Center, New York University School of; Medicine, New York 10016.; We have studied the development of the antibody response to the surface glycoprotein gp120 of human immunodeficiency virus type 1 in three individuals who presented with primary human immunodeficiency virus type 1 infection syndrome. Serum anti-gp120 antibodies were first detected 4 to 23 days after presentation, afte
Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4.: J Virol. 1994 Aug;68(8):5156-63. Unique Identifier : AIDSLINE MED/94309182; Rhee SS; Marsh JW; Laboratory of Molecular Biology, National Institute of Mental; Health, Bethesda, Maryland 20892.; Human immunodeficiency virus type 1 (HIV-1) Nef is a myristylated protein with a relative molecular mass of 27 kDa, is localized to the cytoplasmic surfaces of cellular membranes, and has been reported to down-modulate CD4 in human T cells. To understand the mechanism of HIV-1 Nef-mediated down-modulation of cell surf
Selected mutations of the duck hepatitis B virus P gene RNase H domain affect both RNA packaging and priming of minus-strand DNA synthesis.: J Virol. 1994 Aug;68(8):5232-8. Unique Identifier : AIDSLINE MED/94309190; Chen Y; Robinson WS; Marion PL; Department of Medicine, Stanford University School of Medicine,; California 94305.; The genome of all hepadnaviruses has an open reading frame called the P gene, which encodes a polypeptide of 90 to 97 kDa. The product or products of this P gene are involved in multiple functions of the viral life cycle. These functions include a priming activity which initiates minus-strand DNA synthesis, a polymera
Macrophage-tropic and T-cell line-adapted chimeric strains of human immunodeficiency virus type 1 differ in their susceptibilities to neutralization by soluble CD4 at different temperatures.: J Virol. 1994 Aug;68(8):5264-9. Unique Identifier : AIDSLINE MED/94309194; O'Brien WA; Mao SH; Cao Y; Moore JP; Department of Medicine, Veterans Affairs Medical Center, West Los; Angeles, CA 90073.; Molecular clones of three macrophage-tropic and three T-cell line-adapted strains of human immunodeficiency virus type 1 (HIV-1) were used to explore the mechanism of HIV-1 resistance to neutralization by soluble CD4 (sCD4). The three macrophage-tropic viruses, each possessing the V3 and flanking regions of JR-FL, wer
Specificity and sequence requirements for interactions between various retroviral Gag proteins.: J Virol. 1994 Aug;68(8):5300-5. Unique Identifier : AIDSLINE MED/94309202; Franke EK; Yuan HE; Bossolt KL; Goff SP; Luban J; Department of Medicine, Columbia University, College of; Physicians and Surgeons, New York, New York 10032.; We previously established a genetic assay for retroviral Gag polyprotein multimerization (J. Luban, K. B. Alin, K. L. Bossolt, T. Humaran, and S. P. Goff, J. Virol. 66:5157-5160, 1992). Here we use this assay to demonstrate homomeric interactions between Gag polyproteins encoded by six different retroviruses. Of the G
Single amino acid changes in the human immunodeficiency virus type 1 matrix protein block virus particle production.: J Virol. 1994 Aug;68(8):5311-20. Unique Identifier : AIDSLINE MED/94309204; Freed EO; Orenstein JM; Buckler-White AJ; Martin MA; Laboratory of Molecular Microbiology, National Institute of; Allergy and Infectious Diseases, Bethesda, Maryland 20892.; The matrix protein of human immunodeficiency virus type 1 is encoded by the amino-terminal portion of the Gag precursor and is postulated to be involved in a variety of functions in the virus life cycle. To define domains and specific amino acid residues of the matrix protein that are involved in virus particle assemb
1993 sexually transmitted diseases treatment guidelines. Centers for Disease Control and Prevention.: J Sch Health. 1994 Apr;64(4):156-9. Unique Identifier : AIDSLINE MED/94309252
Behavioral and psychosocial factors related to HIV-infected individuals' knowingly engaging in high-risk behavior.: J Tenn Med Assoc. 1994 Mar;87(3):97-100. Unique Identifier : AIDSLINE MED/94309276; Poku KA; Linn JG; Department of Psychiatry and Behavioral Sciences, Meharry Medical; College, Nashville, TN.
A CD30-positive T cell line established from an aggressive anaplastic large cell lymphoma, originally diagnosed as Hodgkin's disease.: Leukemia. 1994 Jul;8(7):1214-9. Unique Identifier : AIDSLINE MED/94309307; del Mistro A; Leszl A; Bertorelle R; Calabro ML; Panozzo M; Menin C; D'Andrea E; Chieco-Bianchi L; Istituto di Oncologia, CIRC, Universita di Padova, Italy.; Ten months following the diagnosis of Hodgkin s disease (HD), a 46-year-old woman presented cutaneous and leukemic involvement by CD30+ anaplastic large cells, from which a continuously growing, exogenous growth factor-independent T cell line was established. The cultured cells are phenotypically and genotypically T c
Unusual aspects of acute Q fever-associated hepatitis.: Mayo Clin Proc. 1994 Aug;69(8):769-73. Unique Identifier : AIDSLINE MED/94309328; Yale SH; de Groen PC; Tooson JD; Kurtin PJ; Department of Internal Medicine, Mayo Clinic Rochester, Minnesota; 55905.; We describe a 37-year-old farmer with a 3-week history of fevers and hepatitis, in whom Q fever was diagnosed. The diagnosis was based on the findings of characteristic ring granulomas on a bone marrow biopsy specimen and confirmed by complement-fixation antibody tests to Coxiella burnetii. Unusual aspects of this cas
Molecular cloning of a novel human cDNA encoding a zinc finger protein that binds to the interleukin-3 promoter.: Mol Cell Biol. 1994 Aug;14(8):5099-107. Unique Identifier : AIDSLINE GENBANK/D28118; Koyano-Nakagawa N; Nishida J; Baldwin D; Arai K; Yokota T; Department of Molecular and Development Biology, Institute of; Medical Science, University of Tokyo, Japan.; The CT/GC-rich region (-76 to -47) is one transcriptional regulatory region of the interleukin-3 (IL-3) gene which confers basic transcriptional activity and responds to trans-activation by human T-cell leukemia virus type I-encoded Tax. We isolated three types of cDNAs encoding Cys2/His2-type zinc finger proteins tha
Transcriptional suppression of the human T-cell leukemia virus type I long terminal repeat occurs by an unconventional interaction of a CREB factor with the R region.: Mol Cell Biol. 1994 Aug;14(8):5371-83. Unique Identifier : AIDSLINE MED/94309657; Xu X; Brown DA; Kitajima I; Bilakovics J; Fey LW; Nerenberg MI; Department of Neuropharmacology, Scripps Research Institute, La; Jolla, California 92037.; To analyze regulation of the human T-cell leukemia virus type I (HTLV-I) long terminal repeat (LTR), cell lines were generated from LTR-tax x LTR-beta-galactosidase (beta-Gal) doubly transgenic mouse fibroblastic tumors. The HTLV-I LTR directs expression of both the tax and lacZ genes, and Tax up-modulates both promot
The Drosophila tom retrotransposon encodes an envelope protein.: Mol Cell Biol. 1994 Aug;14(8):5392-401. Unique Identifier : AIDSLINE GENBANK/Z24451; Tanda S; Mullor JL; Corces VG; Department of Biology, Johns Hopkins University, Baltimore,; Maryland 21218.; The tom transposable element of Drosophila ananassae is mobilized with high frequency in the germ line of females from the ca; px strain, and its insertion results in mutations that show almost exclusively dominant eye phenotypes. tom is a long terminal repeat-containing retrotransposon that encodes three different op
Cytokine and T-cell subset abnormalities in immunodeficient wasted mice.: Mol Immunol. 1994 Jul;31(10):753-9. Unique Identifier : AIDSLINE MED/94309686; Libertin CR; Ling-Indeck L; Padilla M; Woloschak GE; Department of Pathology, Loyola University Medical Center,; Maywood, IL 60153.; Wasted mice bear an autosomal recessive mutation (wst/wst) that manifests itself in neurologic abnormalities, immunologic deficiency, and faulty DNA repair evident by 21 days of age. The immunodeficiency is characterized by a reduction in the thymus-to-body weight ratio, low levels of IgA plasma cells at secretory sit
Medical care for injection-drug users with human immunodeficiency virus infection [see comments]: N Engl J Med. 1994 Aug 18;331(7):450-9. Unique Identifier : AIDSLINE MED/94309695; O'Connor PG; Selwyn PA; Schottenfeld RS; Department of Medicine, Yale University School of Medicine, New; Haven, CT 06520-8025.
French ministers face public trial in HIV blood affair [news]: Nature. 1994 Jul 28;370(6487):243. Unique Identifier : AIDSLINE MED/94309720; Butler D
HIV in infected lymph nodes [letter; comment]: Nature. 1994 Jul 28;370(6487):256. Unique Identifier : AIDSLINE MED/94309729; Fox CH; Hoover S; Currall VR; Bahre HJ; Cottler-Fox M
Rochalimaea antibodies in HIV-associated neurologic disease.: Neurology. 1994 Jul;44(7):1312-6. Unique Identifier : AIDSLINE MED/94309818; Schwartzman WA; Patnaik M; Barka NE; Peter JB; Section of Infectious Diseases, UCLA Department of Medicine.; Rochalimaea henselae, a recently described pathogen thought to cause syndromes as varied as bacillary angiomatosis , parenchymal bacillary peliosis, fever with bacteremia, and cat-scratch disease, is associated with CNS diseases including cerebral and retinal bacillary angioma
Polymerase chain reaction for rapid diagnosis of tuberculous meningitis in AIDS patients [see comments]: Neurology. 1994 Jul;44(7):1336-8. Unique Identifier : AIDSLINE MED/94309824; Folgueira L; Delgado R; Palenque E; Noriega AR; Department of Microbiology, Hospital Doce de Octubre, Madrid,; Spain.; We used a test based on the polymerase chain reaction (PCR) for the detection of Mycobacterium tuberculosis DNA in 11 CSF samples from 10 HIV-seropositive patients in whom tuberculous meningitis was suspected. PCR was positive in nine samples from eight patients in whom clinical data, CSF findings, evidence of tubercu
Progressive multifocal leukoencephalopathy in HIV infection presenting as Balint's syndrome [see comments]: Neurology. 1994 Jul;44(7):1339-40. Unique Identifier : AIDSLINE MED/94309825; Ayuso-Peralta L; Jimenez-Jimenez FJ; Tejeiro J; Vaquero A; Cabrera-Valdivia F; Madero S; Cabello A; Garcia-Albea E; Section of Neurology, Hospital Principe de Asturias, Madrid,; Spain.; We report a patient with AIDS presenting with Balint s syndrome. CT and MRI showed the characteristic lesions of a progressive multifocal leukoencephalopathy, which was confirmed by histologic examination.
Neuronal loss in HIV [letter; comment]: Neurology. 1994 Jul;44(7):1365-6. Unique Identifier : AIDSLINE MED/94309837; Weis S
Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial. 4. Visual outcomes. Studies of Ocular Complications of AIDS Research Group in collaboration with the AIDS Clinical Trials Group.: Ophthalmology. 1994 Jul;101(7):1250-61. Unique Identifier : AIDSLINE MED/94309875; BACKGROUND: Cytomegalovirus ( CMV ) retinitis is the most common intraocular infection in patients with the acquired immune deficiency syndrome (AIDS) and, untreated, is a blinding disorder. The Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial is a multicente
Oncostatin M activates phosphatidylinositol-3-kinase in Kaposi's sarcoma cells.: Oncogene. 1994 Aug;9(8):2253-60. Unique Identifier : AIDSLINE MED/94309900; Soldi R; Graziani A; Benelli R; Ghigo D; Bosia A; Albini A; Bussolino F; Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy.; Oncostatin M (OM) is a polypeptide cytokine that induces autocrine and paracrine effects on AIDS-Kaposi s sarcoma (KS) cells (Nair et al., Science, 255, 1430-1432, 1992; Miles et al., Science, 255, 1432-1434, 1992). The signalling pathways underlying this activation are largely unknown. We have found that OM binding t
Activation of human immunodeficiency virus 1 gene expression by the src oncoprotein.: Oncogene. 1994 Aug;9(8):2399-403. Unique Identifier : AIDSLINE MED/94309918; Dehbi M; Beaulieu S; Cohen EA; Bedard PA; Departement de Biochimie, Universite de Montreal, Quebec,; Canada.; Several genes are induced constitutively in cells transformed by the v-src oncoprotein. This induction is generally dependent on the activation of transcription factors binding to src-responsive elements of the promoter. In previous studies, we showed that the induction of the CEF-4/9E3 cytokine gene by pp60v-src is d
AZT reduces maternal transmission of HIV.: Pa Med. 1994 May;97(5):30-1. Unique Identifier : AIDSLINE MED/94309927
Cytomegalovirus infection and disease in the immunocompromised host.: Pediatr Infect Dis J. 1994 Apr;13(4):249-57; quiz 257-8. Unique Identifier : AIDSLINE MED/94309935; Mustafa MM; Department of Pediatrics, University of Texas Southwestern; Medical Center, Dallas 75235-9063.
Outcome from perinatal human immunodeficiency virus acquisition [letter]: Pediatr Infect Dis J. 1994 Apr;13(4):336-8. Unique Identifier : AIDSLINE MED/94309957; Gutierrez C; Quintana JM; Pocheville I; Calleja T; Villas P
Predictors of unprotected intercourse among gay and bisexual youth: knowledge, beliefs, and behavior.: Pediatrics. 1994 Aug;94(2 Pt 1):163-8. Unique Identifier : AIDSLINE MED/94309964; Remafedi G; Youth and AIDS Project, University of Minnesota Hospital and; Clinics, Minneapolis 55455-0392.; OBJECTIVE. To examine human immunodeficiency virus (HIV)-related knowledge, attitudes, and behaviors and predictors of unprotected anal intercourse. DESIGN. Structured interviews and paper-and-pencil instruments. SETTING. Community sites in Minnesota during 1989 to 1991. SUBJECTS. Two hundred thirty-nine gay and bisex
Footprinting RNA-protein complexes following gel retardation assays: application to the R-17-procoat-RNA and tat--TAR interactions.: Nucleic Acids Res. 1994 Jun 25;22(12):2255-63. Unique Identifier : AIDSLINE MED/94310052; Pearson L; Chen CB; Gaynor RP; Sigman DS; Department of Biological Chemistry, School of Medicine,; University of California, Los Angeles 90024-1570.; RNA-protein complexes isolated following a gel retardation assay can be footprinted within the gel matrix using the chemical nuclease activities of 4,7-dimethyl-, 5,6-dimethyl-, and 3,4,7,8-tetramethyl-1,10-phenanthroline-copper. These complexes are more reactive than 1,10-phenanthroline-copper but share its reaction
Identification and analysis of the pseudoknot-containing gag-pro ribosomal frameshift signal of simian retrovirus-1.: Nucleic Acids Res. 1994 Jun 25;22(12):2304-10. Unique Identifier : AIDSLINE MED/94310058; ten Dam E; Brierley I; Inglis S; Pleij C; Leiden Institute of Chemistry, Department of Biochemistry,; Gorlaeus Laboratories, Leiden University, The Netherlands.; The pro and pol genes of simian retrovirus-1 (SRV-1) are expressed as parts of a fusion protein generated by -1 ribosomal frameshifting. To investigate the requirements for frameshifting at the gag-pro overlap, we have inserted a stretch of 58 nucleotides containing the proposed frameshift signal into a plasmid that a
[Tuberculosis as an international and national problem]: Probl Tuberk. 1994;(2):2-4. Unique Identifier : AIDSLINE MED/94310126; Khomenko AG
'1994' or '1984' revisited [editorial]: Public Health. 1994 May;108(3):171-2. Unique Identifier : AIDSLINE MED/94310181; Dunlop JM
Blood donor counselling for HIV: results of a multi-country feasibility study.: Public Health. 1994 May;108(3):219-26. Unique Identifier : AIDSLINE MED/94310187; Miller D; Kalibala S; Anderson S; Emmanuel J; Petitgirard A; Department of Public Health Medicine and Epidemiology, University; of Nottingham, UK.; A qualitative characterisation study was conducted by the World Health Organisation s Global Programme on AIDS, and the International Federation of Red Cross and Red Crescent Societies, in six developing countries in order to determine the feasibility of introducing blood donor counselling into procedures for blood do
Ways of maintaining hope in HIV disease.: Res Nurs Health. 1994 Aug;17(4):283-93. Unique Identifier : AIDSLINE MED/94310198; Hall BA; School of Nursing, University of Texas at Austin 78701-1499.; Utilizing Denzin s interpretative interactionism, this study was focused on the experiences of eight men and two women who were in Clinical Category C (AIDS) of HIV Disease. Interviews and analysis revealed their interpretations of the illness and the ways that they maintained hope while coping with end-stage HIV. The
Mode of acquiring AIDS and nurses' intention to provide care [see comments]: Res Nurs Health. 1994 Aug;17(4):303-9. Unique Identifier : AIDSLINE MED/94310200; Cole FL; Slocumb EM; Health Science Center, University of Texas at Houston 77030.; The intention of 322 staff nurses to provide care to male patients who acquired AIDS either through sexual activity with males, sexual activity with females, sharing needles, or a blood transfusion was examined. For each mode of acquiring AIDS, respondents indicated their intent to perform 11 care-giving behaviors, wh
The prognostic value of bronchoalveolar lavage in sarcoidosis.: Sarcoidosis. 1994 Mar;11(1):69-72. Unique Identifier : AIDSLINE MED/94310284; Tukiainen P; Taskinen E; Riska H; Department of Pulmonary Medicine and Pathology, Helsinki; University Central Hospital, Finland.
Treatment options and strategies in uremia: current trends and future directions.: Semin Nephrol. 1994 May;14(3):282-99. Unique Identifier : AIDSLINE MED/94310298; Ismail N; Becker BN; Department of Medicine, Vanderbilt University Medical Center,; Nashville, TN 37232-2372.
[Reparative surgery of the sequelae of noma. Our experience in the Ivory Coast]: Rev Stomatol Chir Maxillofac. 1994;95(2):194-5. Unique Identifier : AIDSLINE MED/94310364; Gadegbeku S; Assa A; Angoh Y; Crezoit G; Adou A; Aka G; Sidibe CA; Bouillet DN; Service de Stomatologie, C.H.U. Cocody, Abidjan, Cote d'Ivoire.
HTLV-II among injecting drug users in Stockholm.: Scand J Infect Dis. 1994;26(2):129-32. Unique Identifier : AIDSLINE MED/94310407; Krook A; Blomberg J; Department of Immunology, Microbiology, Pathology and Infectious; Diseases, Karolinska Institute, Huddinge University Hospital,; Stockholm, Sweden.; 134 injecting drug users (IDUs) treated at the Department of Infectious Diseases of Roslagstull Hospital, Stockholm, were tested for antibodies to human T-lymphotropic virus, types I and II, by means of 2 HTLV-I/-II peptide-based enzyme immunoassays (EIAs), followed by a whole-virus EIA. Positive EIA reactions were ch
Risk factors for listeriosis in Denmark, 1989-1990.: Scand J Infect Dis. 1994;26(2):171-8. Unique Identifier : AIDSLINE MED/94310414; Jensen A; Frederiksen W; Gerner-Smidt P; Department of Clinical Microbiology, Statens Seruminstitut,; Copenhagen S, Denmark.; Dietary risk factors for listeriosis were examined, and the risk levels of listeriosis according to specific underlying diseases were evaluated, in order to study the basis for prevention. Questionnaires from 50 listeriosis patients and 40 matching control persons were analysed. Unpasteurized milk was a risk food for
A highly unusual combination of pulmonary pathogens in an HIV infected patient.: Scand J Infect Dis. 1994;26(2):215-7. Unique Identifier : AIDSLINE MED/94310419; Gillet-Juvin K; Stern M; Israel-Biet D; Penaud D; Carnot F; Department of Pulmonary Diseases, Laennec Hospital, Paris,; France.; We report on a case with an unusual combination of pulmonary pathogens including Pneumocystis carinii, Rhodococcus equi and Toxoplasma gondii in an HIV infected patient. The multiple microbiological procedures required to ascertain the etiological diagnoses of pneumonitis in HIV-seropositive subjects are discussed.
The high-resolution crystal structure of a parallel-stranded guanine tetraplex.: Science. 1994 Jul 22;265(5171):520-4. Unique Identifier : AIDSLINE MED/94310435; Laughlan G; Murchie AI; Norman DG; Moore MH; Moody PC; Lilley DM; Luisi B; Medical Research Council Virology Unit, University of Glasgow,; UK.; Repeat tracts of guanine bases found in DNA and RNA can form tetraplex structures in the presence of a variety of monovalent cations. Evidence suggests that guanine tetraplexes assume important functions within chromosomal telomeres, immunoglobulin switch regions, and the human immunodeficiency virus genome. The struc
The prevalence of informal caregiving to persons with AIDS in the United States: caregiver characteristics and their implications.: Soc Sci Med. 1994 Jun;38(11):1543-52. Unique Identifier : AIDSLINE MED/94310483; Turner HA; Catania JA; Gagnon J; Department of Sociology, University of New Hampshire, Durham; 03824.; Based on U.S. national (N = 2673) and central cities (N = 8263) probability samples, this paper: (1) presents estimates of the proportion of the United States population that has provided informal care to persons with AIDS; (2) identifies socio-demographic characteristics of typical
[The clinical significance of neopterin in human diseases]: Ter Arkh. 1993;65(5):80-7. Unique Identifier : AIDSLINE MED/94310558; Fuchs D; Samsonov MIu; Weiss G; Reibnegger G; Nasonov EL; Wachter H
Tuberculosis--from neglect to control [editorial]: Trans R Soc Trop Med Hyg. 1994 Mar-Apr;88(2):129-31. Unique Identifier : AIDSLINE MED/94310611; Nunn PP; Enarson DA
Childhood malaria parasitaemia and human immunodeficiency virus infection in Malawi.: Trans R Soc Trop Med Hyg. 1994 Mar-Apr;88(2):164-5. Unique Identifier : AIDSLINE MED/94310621; Taha TE; Canner JK; Dallabetta GA; Chiphangwi JD; Liomba G; Wangel AM; Saah AJ; Miotti PG; Department of Epidemiology, Johns Hopkins School of Hygiene and; Public Health, Baltimore, Maryland 21205.
Human T cell lymphotropic virus type 1 in Zimbabwe.: Trans R Soc Trop Med Hyg. 1994 Mar-Apr;88(2):170-2. Unique Identifier : AIDSLINE MED/94310624; Houston S; Thornton C; Emmanuel J; Latif A; University of Zimbabwe Medical School, Avondale, Harare.; Human T cell lymphotrophic virus type 1 (HTLV-1) causes myelopathy and adult T cell leukaemia. Knowledge of its distribution in Africa is limited. We performed HTLV-1 testing by enzyme immunoassay, with immunofluorescence assay confirmation, on 931 blood donors, 88 human immunodeficiency virus (HIV) seronegative patie
Anaemia, blood transfusion practices, HIV and mortality among women of reproductive age in western Kenya.: Trans R Soc Trop Med Hyg. 1994 Mar-Apr;88(2):173-6. Unique Identifier : AIDSLINE MED/94310625; Zucker JR; Lackritz EM; Ruebush TK; Hightower AW; Adungosi JE; Were JB; Campbell CC; Malaria Branch, Centers for Disease Control and Prevention,; Public Health Service, US Department of Health and Human; Services, Atlanta, GA 30333.; Severe anaemia among women in sub-Saharan Africa is frequently treated with blood transfusions. The risk of transmission of human immunodeficiency virus (HIV) through blood products has led to a re-evaluation of the indications for transfusions. Prospective surveillance of women admitted to a district hospital in west
Tuberculosis and HIV infection in children in Abidjan, Cote d'Ivoire.: Trans R Soc Trop Med Hyg. 1994 Mar-Apr;88(2):178-81. Unique Identifier : AIDSLINE MED/94310627; Sassan-Morokro M; De Cock KM; Ackah A; Vetter KM; Doorly R; Brattegaard K; Coulibaly D; Coulibaly IM; Gayle H; Projet RETRO-CI, Abidjan, Cote d'Ivoire.; Of 5180 consecutive outpatients diagnosed with tuberculosis in Abidjan, Cote d Ivoire (West Africa), between July 1989 and December 1990, 289 (6%) were children aged less than 15 years. The overall prevalence of human immunodeficiency virus (HIV) 1 and/or HIV-2 infection in ch
One year's experience with Cryptococcus neoformans in Thailand.: Trans R Soc Trop Med Hyg. 1994 Mar-Apr;88(2):208. Unique Identifier : AIDSLINE MED/94310640; Imwidthaya P; Department of Microbiology, Siriraj Hospital, Mahidol University,; Bangkok, Thailand.
Regulation of the human immunodeficiency virus type 1 long terminal repeat: interactions of thyroid hormone receptor with retinoid-X receptor, nuclear factor kappa B, Sp1, and Tat.: Trans Assoc Am Physicians. 1993;106:13-32. Unique Identifier : AIDSLINE MED/94310719; Desai-Yajnik V; Samuels HH; Department of Pathology, New York University Medical Center, NY; 10016.
Use of synthetic peptides in primates to induce high-titered neutralizing antibodies and MHC class I-restricted cytotoxic T cells against acquired immunodeficiency syndrome retroviruses: an HLA-based vaccine strategy.: Trans Assoc Am Physicians. 1993;106:33-41. Unique Identifier : AIDSLINE MED/94310728; Haynes BF; Yasutomi Y; Torres JV; Gardner MB; Langlios AJ; Bolognesi DP; Matthews TJ; Scearce RM; Jones DM; Moody MA; et al; Department of Medicine, Duke University Arthritis Center, Durham,; NC.
Human monoclonal antibodies against Cryptosporidium parvum generated by hypo-osmolar electrofusion.: Trans Assoc Am Physicians. 1993;106:86-90. Unique Identifier : AIDSLINE MED/94310734; Flanigan TP; Wisnewski A; Wiest PM; Johnson J; Tzipori S; Hamer D; Lam N; Kresina TF; Department of Medicine, Miriam Hospital, Brown University,; Providence, RI 02906.
Evaluation of a new saliva collection device for HIV antibody screening purposes [letter]: Vox Sang. 1994;66(3):244. Unique Identifier : AIDSLINE MED/94310793; Gomez C; Gutierrez M; Martinez-Acacio P; Soriano V
Viral transformation of human T lymphocytes.: Adv Cancer Res. 1994;63:211-44. Unique Identifier : AIDSLINE MED/94311073; Grassmann R; Fleckenstein B; Desrosiers RC; Institut fur Klinische and Molekulare Virologie, Universitat; Erlangen--Nurnberg, Erlangen, Germany.
Diagnosis of intracranial lymphoma in patients with AIDS: value of 201TI single-photon emission computed tomography.: AJR Am J Roentgenol. 1994 Aug;163(2):417-21. Unique Identifier : AIDSLINE MED/94311132; O'Malley JP; Ziessman HA; Kumar PN; Harkness BA; Tall JG; Pierce PF; Department of Radiology, Georgetown University Hospital,; Washington, DC 20007.; OBJECTIVE. Although the prevalence of intracranial lymphoma is high among patients with AIDS, current imaging techniques are not reliable for differentiating this tumor from other common nonneoplastic lesions, such as those seen in toxoplasmosis. The purpose of this study was to prospectively investigate the use of 20
A review of AIDS policies at schools for deaf and hard of hearing students.: Am Ann Deaf. 1994 Mar;139(2):86-95. Unique Identifier : AIDSLINE MED/94311172; Deyo DA; Department of Special Education Administration, Gallaudet; University.; Surveys completed by state boards of education and state schools for the deaf and hard of hearing in 39 states/territories provided information about policies regarding students with HIV+/AIDS. In addition, copies of the actual policies were provided by some survey respondents. Analysis of the survey data and content
Salivary lymphadenopathy and HIV [letter]: Am J Clin Pathol. 1994 Jul;102(1):142. Unique Identifier : AIDSLINE MED/94311257; Ioachim HL; Ryan JR
Current topics in protozoal diseases [published erratum appears in Am J Clin Pathol 1994 Nov;102(5):708] [see comments]: Am J Clin Pathol. 1994 Jul;102(1):16-29. Unique Identifier : AIDSLINE MED/94311259; Sun T; Department of Laboratories, North Shore University; Hospital-Cornell University Medical College, Manhasset, New York; 11030.; The author reviews seven protozoal diseases, emphasizing the current development but also briefly reviewing the basic knowledge in epidemiology, parasitology, clinical features, pathology, and laboratory diagnosis. Cryptosporidiosis, microsporidiosis , and cyclosporiasi
CDC report recommends eliminating barriers to needle-exchange programs. Key role of pharmacists in programs is envisioned [news]: Am J Hosp Pharm. 1994 Apr 15;51(8):960. Unique Identifier : AIDSLINE MED/94311333
Octreotide for HIV-related diarrhea.: Am J Hosp Pharm. 1994 Apr 15;51(8):996, 1001. Unique Identifier : AIDSLINE MED/94311336; Kovelesky RA; Minor JR; Pharmacy Department, Warren G. Magnuson, Clinical Center,; National Institutes of Health, Bethesda, MD 20892.
Recurrent and de novo giant cell hepatitis after orthotopic liver transplantation.: Am J Surg Pathol. 1994 Aug;18(8):804-13. Unique Identifier : AIDSLINE MED/94311410; Pappo O; Yunis E; Jordan JA; Jaffe R; Mateo R; Fung J; Demetris AJ; Department of Pathology, University of Pittsburgh, PA 15213.; This study examines the clinical and pathologic course of seven patients who developed giant cell hepatitis (GCH) after liver transplantation. Five of these patients also had GCH as their native liver disease and experienced a particularly aggressive course because of recurrent disease, beginning 1-21 months after tra
Splenic rupture in hemophilia.: Am J Pediatr Hematol Oncol. 1994 Aug;16(3):255-9. Unique Identifier : AIDSLINE MED/94311464; Fort DW; Bernini JC; Johnson A; Cochran CJ; Buchanan GR; Department of Pediatrics, University of Texas Southwestern; Medical Center, Dallas.; PURPOSE: Little information is available regarding splenic injury in patients with hemophilia. We describe here the management of splenic rupture in five of our patients with hemophilia and summarize the literature describing this complication. PATIENTS AND METHODS: Two human immunodeficiency virus-seropositive patien
[Mikulicz disease as the beginning of AIDS]: An Otorrinolaringol Ibero Am. 1994;21(3):281-7. Unique Identifier : AIDSLINE MED/94311491; Guiral H; Risco J; Razquin S; Pellicer E; Figuerola E; Mayayo E; Ano T; Servicio de O.R.L. Hospital Joan XXIII, Tarragona.; Major salivary lymphoepithelial lesions accounted for less than 3 percent of all benign parotid tumors, prior to AIDS acquaintance. Defined as the presence of enlargement of one or more salivary glands and, in some cases, with diminished salivary function. The paper present the case of an acquired immunodeficiency syn
Human immunodeficiency virus infection among health care workers who donate blood.: Ann Intern Med. 1994 Aug 15;121(4):269-73. Unique Identifier : AIDSLINE MED/94311535; Chamberland ME; Petersen LR; Munn VP; White CR; Johnson ES; Busch MP; Grindon AJ; Kamel H; Ness PM; Shafer AW; et al; Centers for Disease Control and Prevention, Atlanta, GA.; OBJECTIVE: To estimate the prevalence of human immunodeficiency virus (HIV) infection among health care workers who donate blood. DESIGN: Point prevalence survey of blood donors. SETTING: 20 U.S. blood centers that participate in an ongoing interview study of HIV-seropositive blood donors. MEASUREMENTS: Prevalence rat
Mandatory HIV testing [letter; comment]: Ann Intern Med. 1994 Aug 15;121(4):309; discussion 310. Unique Identifier : AIDSLINE MED/94311549; Buckingham WB
Mandatory HIV testing [letter; comment]: Ann Intern Med. 1994 Aug 15;121(4):309; discussion 310. Unique Identifier : AIDSLINE MED/94311550; Weissman E
Experimental large-animal model of obliterative bronchiolitis after lung transplantation.: Ann Thorac Surg. 1994 Jul;58(1):34-9; discussion 39-40. Unique Identifier : AIDSLINE MED/94311708; al-Dossari GA; Kshettry VR; Jessurun J; Bolman RM 3rd; Division of Cardiovascular and Thoracic Surgery, University of; Minnesota, Minneapolis 55455-0392.; Obliterative bronchiolitis is a major cause of long-term morbidity after lung transplantation. It is characterized by small-airway inflammation and occlusion by fibrous tissue. The pathogenesis is uncertain. To study this disease, we developed a model of posttransplantation obliterative bronchiolitis using genetically
[Electron-microscopic study of the lymph nodes and brain of children with a clinical diagnosis of HIV-infection]: Arkh Patol. 1994 Mar-Apr;56(2):49-53. Unique Identifier : AIDSLINE MED/94311748; Matsionis AE; Zhishchenko ZhA; KhusainovaIS; Povilaitite; Ultrastructural changes in lymph nodes and brain of 7 children with AIDS who died in 1991-1993 in the city of Rostov-on-Don and the Rostov Region have been studied. The results obtained indicated only one case with ultrastructural signs characteristic of AIDS: virus particles with relevant morphology, tubular ring-sha
IL-10 inhibits HIV-1 replication and is induced by tat.: Biochem Biophys Res Commun. 1994 Jul 15;202(1):374-83. Unique Identifier : AIDSLINE MED/94311907; Masood R; Lunardi-Iskandar Y; Moudgil T; Zhang Y; Law RE; Huang CL; Puri RK; Levine AM; Gill PS; Department of Medicine, University of Southern California, Los; Angeles 90033.; Interleukin 10 (IL-10) is produced by TH2 lymphocytes and regulates both lymphoid and myeloid cells. In the present study we demonstrate that IL-10 is expressed and produced spontaneously in the peripheral blood mononuclear cells (PBMCs) of all HIV-1 infected individuals tested, 3 of 19 cases of HIV-negative lymphoma
Lymphocytes and promonocytes attach to the synthetic [Tyr5,12, Lys7]- polyphemusin II peptide.: Biochem Biophys Res Commun. 1994 Jul 15;202(1):470-5. Unique Identifier : AIDSLINE MED/94311923; Weeks BS; Nomizu M; Otaka A; Weston CA; Okusu A; Tamamura H; Matsumoto A; Yamamoto N; Fujii N; Department of Biology, Hamilton College, Clinton, New York 13323.; The [Tyr5,12,Lys7]-polyphemusin II peptide (T22) has been shown to inhibit HIV-1 replication in lymphocytes. The mechanism of T22 inhibition of HIV-1 replication is not known but may involve T22 competition with HIV-1 for attachment sites on the plasma membrane of targeted cells. Here we find that three human immunocy
When an employee is HIV positive.: AAOHN J. 1994 May;42(5):241-6; quiz 247-8. Unique Identifier : AIDSLINE MED/94311994; DeMarzo C; Goodgame J; The occupational health nurse is the primary workplace educator in the HIV pandemic. The policies and methods used to manage the employee with HIV must protect the confidentiality of the employee without discrimination. The occupational health nurse has a unique responsibility to monitor the disease progression and re
[AIDS and its interaction with tuberculosis in Latin America and the Caribbean]: Bol Oficina Sanit Panam. 1994 Mar;116(3):250-63. Unique Identifier : AIDSLINE MED/94312018; Zacarias F; Gonzalez RS; Cuchi P; Yanez A; Peruga A; Mazin R; Betts C; Weissenbacher M; Organizacion Panamericana de la Salud, Programa Regional de SIDA; y Enfermedades de Transmision Sexual, Washington, D.C.
[Association between tuberculosis and human immunodeficiency virus infection in Argentina]: Bol Oficina Sanit Panam. 1994 Apr;116(4):356-66. Unique Identifier : AIDSLINE MED/94312022; de Kantor IN; Astarloa L; Gonzalez Montaner LJ; INPPAZ, Organizacion Panamericana de la Salud, Area de; Tuberculosis, Washington, D.C.
Isolated bulbar conjunctival Kaposi's sarcoma.: Aust N Z J Ophthalmol. 1994 Feb;22(1):81-2. Unique Identifier : AIDSLINE MED/94312111; Murray N; McCluskey P; Wakefield D; Beaumont P; Laboratory of Ocular Immunology, School of Pathology, Kensington,; NSW.; We present a case of an isolated bulbar conjunctival Kaposi s sarcoma in a man with HIV infection. This is an unusual site for the initial presentation of Kaposi s sarcoma and in this site can be confused with a caroticocavernous fistula, cavernous haemangioma or chronic subconjunctival haemorrhage. Biopsy is required
Survey of employers' policies on HIV and AIDS in North Nottinghamshire.: J Public Health Med. 1994 Mar;16(1):101-4. Unique Identifier : AIDSLINE MED/94312131; Whelan S; Mousley AA; Wight JP; Department of Public Health Medicine, Ransom Hospital, Rainworth,; Mansfield, Nottinghamshire.; To ascertain the extent to which local employers in North Nottinghamshire currently have policies for dealing with AIDS/HIV in the workplace, and the areas covered by any such policies, a survey of 148 companies was carried out. Eighty-six companies returned completed questionnaires (58 per cent). Of these, 17 reporte
Quarterly Communicable Disease Review July to September 1993. From the PHLS Communicable Disease Surveillance Centre.: J Public Health Med. 1994 Mar;16(1):105-12. Unique Identifier : AIDSLINE MED/94312132
Utrecht venue for HIV conference on nurse education [news]: Nurs Stand. 1994 May 25-31;8(35):11. Unique Identifier : AIDSLINE MED/94312291
Kaposi's sarcoma in an HIV-negative CLL patient as the cause of thrombocytopenia.: Ann Hematol. 1994 Jun;68(6):307-10. Unique Identifier : AIDSLINE MED/94312469; Wijermans PW; van Groningen K; van Royen EA; Bruijn JA; Department of Hematology, Municipal Hospital Leyenburg, The; Hague, The Netherlands.; A patient is described with a rapidly progressive Kaposi s sarcoma following immunosuppressive therapy with fludarabine monophosphate (FAMP) for chronic lymphocytic leukemia. The development of this tumor was accompanied by progressive thrombocytopenia, due to trapping of the platelets in the Kaposi sarcoma, without s
Low serum lipoprotein(a) and beta 2-glycoprotein I levels in HIV-1-positive hemophiliacs [letter]: Ann Hematol. 1994 Jun;68(6):315-6. Unique Identifier : AIDSLINE MED/94312471; Matsuda J; Saitoh N; Gohchi K; Gotoh M; Tsukamoto M
Temporal association between implementation of universal precautions and a sustained, progressive decrease in percutaneous exposures to blood.: Clin Infect Dis. 1994 Apr;18(4):562-9. Unique Identifier : AIDSLINE MED/94312554; Beekmann SE; Vlahov D; Koziol DE; McShalley ED; Schmitt JM; Henderson DK; Hospital Epidemiology Service, Clinical Center, National; Institutes of Health, Bethesda, Maryland 20892.; To evaluate whether implementation of universal precautions was temporally associated with a decrease in reported parenteral exposures to blood, we analyzed data on self-reported parenteral injuries that were prospectively collected at the Clinical Center, National Institutes of Health (Bethesda, MD), from 1985 throug
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC).: Clin Infect Dis. 1994 Apr;18(4):570-8. Unique Identifier : AIDSLINE MED/94312555; Snoeck R; Andrei G; Gerard M; Silverman A; Hedderman A; Balzarini J; Sadzot-Delvaux C; Tricot G; Clumeck N; De Clercq E; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.; The acyclic nucleoside phosphonate (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) was used topically for the treatment of persistent mucocutaneous infections in two cases. One patient with AIDS suffered from a perineal lesion due to infection with herpes simplex virus type 2 (HSV-2) and did not respond to
Infectious complications of tattoos.: Clin Infect Dis. 1994 Apr;18(4):610-9. Unique Identifier : AIDSLINE MED/94312562; Long GE; Rickman LS; Division of Infectious Diseases, University of California San; Diego.; Tattooing carries several medical risks, including the transmission of infectious diseases. We review the published literature on the transmission of hepatitis B virus, human immunodeficiency virus, Treponema pallidum, papillomavirus, Mycobacterium tuberculosis, and other organisms by tattooing. Education, through pub
Cyclospora: a newly identified intestinal pathogen of humans.: Clin Infect Dis. 1994 Apr;18(4):620-3. Unique Identifier : AIDSLINE MED/94312563; Wurtz R; Division of Infectious Disease, Cook County Hospital, Chicago,; Illinois 60612.; A number of reports over the last several years have linked a previously unidentified acid-fast organism with prolonged diarrhea in humans. Initially thought to be a cyanobacterium, the organism has been identified as a coccidian protozoan of the genus Cyclospora, and the name Cyclospora cayetanensis has been proposed
Adverse reactions to dapsone in persons infected with human immunodeficiency virus.: Clin Infect Dis. 1994 Apr;18(4):630-2. Unique Identifier : AIDSLINE MED/94312566; Pertel P; Hirschtick R; Division of Infectious Diseases, Northwestern University, Medical; School, Chicago, Illinois 60611.; Dapsone is used in prophylaxis for and treatment of Pneumocystis carinii pneumonia. We present a case of Stevens-Johnson syndrome that was likely induced by administration of dapsone. A review of charts at the HIV Treatment Center of Northwestern University (Chicago) revealed that 40.3% of patients treated with trimet
Progressive immunodeficiency due to infection with human immunodeficiency virus does not lead to waning immunity to measles in a cohort of homosexual men.: Clin Infect Dis. 1994 Apr;18(4):636-8. Unique Identifier : AIDSLINE MED/94312568; Zolopa AR; Kemper CA; Shiboski S; Hamilton JR; Moss AR; Deresinski SC; Department of Epidemiology and Biostatistics, University of; California, San Francisco 94110.; The relationship between progressive immunodeficiency related to infection with human immunodeficiency virus (HIV) and waning immunity to measles was investigated in this retrospective cohort study. Titers of serum antibodies to measles virus were measured by enzyme immunoassay of stored sera from a cohort of homosexu
Tuberculosis mimicking acute appendicitis in patients with human immunodeficiency virus infection [letter]: Clin Infect Dis. 1994 Apr;18(4):650-1. Unique Identifier : AIDSLINE MED/94312572; Dezfuli M; Oo MM; Jones BE; Barnes PF
Yersinia enterocolitica peritonitis in a patient infected with the human immunodeficiency virus [letter]: Clin Infect Dis. 1994 Apr;18(4):655-6. Unique Identifier : AIDSLINE MED/94312576; Flament-Saillour M; de Truchis P; Risbourg M; Nordmann P
Clarithromycin: a potent agent against infections due to Mycobacterium marinum [letter]: Clin Infect Dis. 1994 Apr;18(4):664-6. Unique Identifier : AIDSLINE MED/94312584; Bonnet E; Debat-Zoguereh D; Petit N; Ravaux I; Gallais H
Pneumocystis carinii pneumonia: relationship between cyst size and response to treatment.: Cytopathology. 1994 Apr;5(2):90-2. Unique Identifier : AIDSLINE MED/94312680; Wazir JF; Wadsworth J; Coleman DV; Department of Cytopathology, Saint Mary's Hospital, London, UK.; Pneumocystis carinii pneumonia is a common cause of death in patients with AIDS. Diagnosis is based on cytological examination of smears prepared from induced sputum samples and bronchoalveolar lavage (BAL) specimens which have been stained with methenamine silver. We have examined 46 BAL/induced sputum specimens from
Medicaid policies for HIV-related drug therapies: perspectives of the state affiliates of the American Pharmaceutical Association.: Ann Pharmacother. 1994 Apr;28(4):528-35. Unique Identifier : AIDSLINE MED/94312742; Buchanan RJ; Smith SR; Department of Community Health, University of Illinois, Champaign; 61820.; OBJECTIVES: To determine how Medicaid prescription drug policies differ by state, and to assess how these policies affect pharmacies and the drug therapies available to Medicaid patients with HIV infection or tuberculosis. EVALUATION PROCESS: The state affiliates of the American Pharmaceutical Association (APhA) were
Adult T cell leukaemia-lymphoma.: Baillieres Clin Haematol. 1993 Dec;6(4):899-915. Unique Identifier : AIDSLINE MED/94312759; Yamaguchi K; Takatsuki K; Blood Transfusion Service, Kumamoto University Medical School,; Japan.; Adult T cell leukaemia-lymphoma (ATL) was first discovered and reported in Japan , where it has a high incidence in the south-west region. The first human retrovirus HTLV-I (human T-cell lymphotropic virus type I) is considered to be related to its aetiology. In ATL endemic areas, HT
Methylprednisolone bolus: a novel therapy for severe atopic dermatitis.: Acta Paediatr. 1994 Mar;83(3):315-7. Unique Identifier : AIDSLINE MED/94312804; Galli E; Chini L; Moschese V; Paone F; Menichelli A; Fraioli G; Rossi P; Institute of Paediatrics, University of Rome Tor Vergata, Italy.; Seven children suffering from severe atopic dermatitis, unresponsive to standard therapy, received an iv bolus dose of methylprednisolone (20 mg/kg/day) for three days. Immunological parameters were evaluated before and after treatment. At the end of bolus therapy both skin lesions and itching improved for several mon
Lymphocyte subsets in infants with wheezy bronchitis.: Acta Paediatr. 1994 Mar;83(3):333-4. Unique Identifier : AIDSLINE MED/94312809; Rylander E; Persson U; Eriksson M; Department of Pediatrics, St Goran's Children's Hospital,; Stockholm, Sweden.
A p12 gag gene homologue is present in the mouse genome.: Biochem Mol Biol Int. 1994 Mar;32(4):691-6. Unique Identifier : AIDSLINE GENBANK/M26005; Casabianca A; Magnani M; Institute of Biological Chemistry G. Fornaini, University of; Urbino, Italy.; A replication-defective virus (BM5d) of approximately 4.9 kb, is responsible for a retrovirus induced immunodeficiency syndrome in mice (MAIDS) that shares many features with AIDS. BM5d is characterized by deletions in env and pol genes, furthermore its gag gene differs markedly from gag of other BM5 ecotropic viruses
Seroprevalence of HIV-1 in a male medium security penitentiary--Ontario [comment]: Can Commun Dis Rep. 1994 Mar 30;20(6):45-7. Unique Identifier : AIDSLINE MED/94313048; Ford PM; Alifo A; Connop PJ; Panaro L; Zoutman D; Department of Medicine, Queen's University, Kingston, Ontario.
HIV studies among inmates in Canadian prisons: a review [see comments]: Can Commun Dis Rep. 1994 Mar 30;20(6):47-9. Unique Identifier : AIDSLINE MED/94313049; Strike C; Sutherland D; Division of HIV/AIDS Epidemiology, Bureau of Communicable Disease; Epidemiology, LCDC, Ottawa.
STDs and the sexual abuse of children [editorial]: Br J Hosp Med. 1994 Mar 2-15;51(5):206-8. Unique Identifier : AIDSLINE MED/94313305; Forster GE
[Sports and AIDS]: Bull Acad Natl Med. 1994 Jan;178(1):97-106. Unique Identifier : AIDSLINE MED/94313403; Chretien J
[Prostitution and AIDS. Potential role of prostitution in the transmission of HIV]: Bull Acad Natl Med. 1994 Feb;178(2):187-98. Unique Identifier : AIDSLINE MED/94313405; Morel P; Civatte J
[Methods for AIDS prevention: importance and limitations of use of bleach]: Bull Acad Natl Med. 1994 Feb;178(2):279-88; discussion 288-01. Unique Identifier : AIDSLINE MED/94313413; Ingold FR; Toussirt M; Jacob C; Institut de Recherche en Epidemiologie de la; Pharmacodependance, Paris.; The authors are discussing the interest of promoting the use of bleach as a powerful disinfectant among drug users. Following the researches conducted in the United States of America, the use of bleach has been introduced on an experimental basis in Paris. This action-research allowed
Number of AIDS cases in Canada may be much higher than total documented: LCDC [news]: Can Med Assoc J. 1994 Aug 1;151(3):337. Unique Identifier : AIDSLINE MED/94313502
Government struggles to develop action plan as concern about AIDS grows in Japan.: Can Med Assoc J. 1994 Aug 1;151(3):351-2. Unique Identifier : AIDSLINE MED/94313506; Audet B
Periodontal complications of HIV infection.: Compendium. 1994;Suppl 18:S694-8; quiz S714-7. Unique Identifier : AIDSLINE MED/94313640; Greenspan JS; Department of Stomatology, School of Dentistry, University of; California at San Francisco.; As the scope of the acquired immunodeficiency syndrome (AIDS) epidemic grows to include increasingly larger proportions of heterosexual adults and children, there has also been a change in the severity of human immunodeficiency virus (HIV)-related periodontal conditions at one San Francisco clinic. The cases of HIV-as
Gallium-avid painless thyroiditis in a patient with AIDS.: Clin Nucl Med. 1994 May;19(5):413-5. Unique Identifier : AIDSLINE MED/94313777; Achong DM; Snow KJ; Department of Radiology, New England Medical Center, Boston,; Massachusetts 02111.; Intense thyroidal Ga-67 accumulation was seen in a man with AIDS imaged for suspected Pneumocystis carinii pneumonia. Concurrent Tc-99m pertechnetate thyroid scanning demonstrated absent trapping, helping establish the diagnosis of painless thyroiditis. Occult hyperthyroidism, and not pulmonary infection, may have bee
An inflammatory lesion in an HIV-positive bleeder detected by Tc-99m labeled antigranulocyte antibodies.: Clin Nucl Med. 1994 May;19(5):459-60. Unique Identifier : AIDSLINE MED/94313789; Menzel C; Grunwald F; Holzknecht N; Hotze AL; Biersack HJ; Department of Nuclear Medicine, University of Bonn, Germany.
Hemophiliac arthropathy. Appearance on bone scintigraphy.: Clin Nucl Med. 1994 May;19(5):465-6. Unique Identifier : AIDSLINE MED/94313793; Bender JM; Unalan M; Balon HR; Nagle CE; Nuclear Medicine Department, William Beaumont Hospital, Royal; Oak, MI 48073-6769.
Thallium and gallium scintigraphy in pulmonary Kaposi's sarcoma in an HIV-positive patient [see comments]: Clin Nucl Med. 1994 May;19(5):467-8. Unique Identifier : AIDSLINE MED/94313794; Del val Gomez MA; Castro Beiras JM; Gallardo FG; Verdejo J; Nuclear Medicine Department, Instituto de Salud, Carlos III,; Madrid, Spain.
Assistance for Colorado physicians treating HIV. The Children's Hospital Immunodeficiency Program (CHIP) [news]: Colo Med. 1994 Mar;91(3):113-4. Unique Identifier : AIDSLINE MED/94313806
Predictors of outcome in methadone programs: effect of HIV counseling and testing.: Conn Med. 1994 Mar;58(3):165-71. Unique Identifier : AIDSLINE MED/94313846; Farley TA; Cartter ML; Wassell JT; Hadler JL; Division of Field Services, Centers for Disease Control, Atlanta,; Georgia.; OBJECTIVE: To identify predictors of treatment outcomes in methadone maintenance programs and to determine whether HIV counseling and testing influenced these outcomes. DESIGN: Retrospective record review. SETTING: Four methadone maintenance programs in four cities in Connecticut, USA. PARTICIPANTS: Five hundred and n
[HIV-associated cholangiopathy]: Dtsch Med Wochenschr. 1994 Jul 15;119(28-29):1004-5. Unique Identifier : AIDSLINE MED/94313914; Spengler U; Rockstroh JK; Sauerbruch T; Abteilung Allgemeine Innere Medizin, Medizinische; Universitatsklinik, Bonn.
[Behavior associated with HIV-1 infection in drug addicts in Rome, 1990-1992]: Epidemiol Prev. 1994 Mar;18:49-55. Unique Identifier : AIDSLINE MED/94314056; Abeni DD; Davoli M; Perucci CA; Forastiere F; Brancato G; Montiroli PM; Zampieri F; Arca M; Osservatorio Epidemiologico, Regione Lazio.; Two cross-sectional surveys have been conducted in Rome in 1990 and 1992 to investigate prevalence and temporal differences of risk behaviours among drug injectors. A total of 487 drug injectors in 1990, and 450 in 1992 have been interviewed both in the street and in treatment services. Twenty-four percent of the subj
Family planning needs of male chronic mental patients in the general hospital psychiatry clinic.: Gen Hosp Psychiatry. 1994 Jan;16(1):38-41. Unique Identifier : AIDSLINE MED/94314192; Coverdale JH; Schotte D; Ruiz P; Pharies S; Bayer T; Department of Psychiatry, Baylor College of Medicine, Houston,; Texas.; We investigated the parenting history, contraceptive behavior, and contraceptive needs of 35 male chronic mental patients seen at an urban outpatient psychiatric clinic. Most patients had fathered children, but 60% of the children less than 16 years of age were not being reared by their biological father. Forty-one pe
HIV-dementia and suicide.: Gen Hosp Psychiatry. 1994 Jan;16(1):45-6. Unique Identifier : AIDSLINE MED/94314195; Alfonso CA; Cohen MA; New York Medical College, Metropolitan Hospital Center, New York.; Suicide is a dangerous concomitant of HIV- dementia . Impulsivity, impaired judgment, lability, and disinhibition are associated with dementia. The authors describe two suicidal individuals with HIV-dementia.
Neuroleptic-induced akathisia in an HIV-infected individual [letter]: Gen Hosp Psychiatry. 1994 Jan;16(1):57-8. Unique Identifier : AIDSLINE MED/94314198; Ioannou C; Viswanathan R
Lilliputian hallucinations and medical illness.: Gen Hosp Psychiatry. 1994 Mar;16(2):141-3. Unique Identifier : AIDSLINE MED/94314206; Cohen MA; Alfonso CA; Haque MM; New York Medical College, Metropolitan Hospital Center, New York.; Lilliputian hallucinations have been described in patients with delirium, schizophrenia, seizure disorders, visual disturbances, and brain tumors. The authors report two cases of patients with lilliputian hallucinations, one with AIDS- dementia complex and the other with dementia fo
A sensitive promoter assay based on the transcriptional activator Tat of the HIV-1 virus.: Gene. 1994 Jul 8;144(2):243-7. Unique Identifier : AIDSLINE MED/94314223; Koken SE; van Wamel J; Berkhout B; Department of Virology, University of Amsterdam, The Netherlands.; We developed a sensitive vector system for the analysis of weak promoter activities. This promoter assay is based on the transcriptional activator protein, Tat, of human immunodeficiency virus type 1 (HIV-1). High-level expression of HIV requires activation in trans by Tat of the promoter in the long terminal repeat (
Risk factors for gonorrhoea, syphilis, and trichomonas infections among women attending family planning clinics in Nairobi, Kenya.: Genitourin Med. 1994 Jun;70(3):155-61. Unique Identifier : AIDSLINE MED/94314301; Daly CC; Maggwa N; Mati JK; Solomon M; Mbugua S; Tukei PM; Hunter DJ; Department of Epidemiology, Harvard School of Public Health,; Boston, MA 02115.; OBJECTIVE--To identify the risk factors for gonorrhoea, syphilis, and trichomonas infections among low risk women in Nairobi, Kenya . METHOD--In a cross-sectional study, 4,404 women attending two peri-urban family planning clinics between 1989 and 1991 were interviewed using a struct
An outbreak of a penicillin-sensitive strain of gonorrhoea in Sydney men [see comments]: Genitourin Med. 1994 Jun;70(3):196-9. Unique Identifier : AIDSLINE MED/94314309; Rowbottom JH; Tapsall JW; Plummer DC; Bodsworth NJ; MacDonald MA; Chambers IW; Kaldor JM; National Centre in HIV Epidemiology and Clinical Research,; University of New South Wales, Sydney, Australia.; OBJECTIVE--To describe an outbreak of gonorrhoea caused by penicillin sensitive Wild type 1B2-Wt/1B2(FS), in homosexual men in Sydney. DESIGN AND SETTING--The study sample comprised all gonococcal isolates referred to the Gonococcal Reference Laboratory (GRL), New South Wales, Austr
Seroprevalence, risk factors and attitude to HIV-1 in a representative sample of lesbians in Turin.: Genitourin Med. 1994 Jun;70(3):200-5. Unique Identifier : AIDSLINE MED/94314310; Raiteri R; Fora R; Gioannini P; Russo R; Lucchini A; Terzi MG; Giacobbi D; Sinicco A; Institute of Infectious Diseases, University of Turin, Italy.; OBJECTIVE--To estimate the HIV-1 seroprevalence, behavioural risks and attitude to HIV-1 infection among lesbians. SETTING--Institute of Infectious Diseases, University of Turin, Italy . SUBJECTS--From March 1992 to May 1993, 181 lesbians were tested for HIV-1 and included in the stu
Transmission of hepatitis C virus but not human immunodeficiency virus type 1 following sharing of cleaned injecting equipment.: Genitourin Med. 1994 Jun;70(3):206-7. Unique Identifier : AIDSLINE MED/94314311; Bodsworth NJ; Robertson M; Kaldor J; Sydney Sexual Health Centre, Sydney Hospital, NSW, Australia.
The history of venereology in Norway.: Genitourin Med. 1994 Jun;70(3):215-7. Unique Identifier : AIDSLINE MED/94314313; Fyrand O; Granholt A; Department of Dermatology National Hospital, Rikshospitalet,; Oslo.; Syphilis became a problem at the beginning of the eighteenth century when a virulent microbe was brought to Norway . This new disease was called radesyken, a Nordic name for the wicked disease. Rade hospitals were built and this was the beginning of the Norwegian hospital system. Pr
Spinal cord disease due to vacuolar myelopathy in AIDS [clinical conference]: Genitourin Med. 1994 Jun;70(3):222-7. Unique Identifier : AIDSLINE MED/94314315; Miller RF; Sweeney B; Harrison MJ; Lucas SB; Department of Medicine, University College London Medical School,; UK.
Influence of suramin on the expression of Fc receptors and other markers on human monocytes and U937 cells, and on their phagocytic properties.: Immunology. 1994 Apr;81(4):598-604. Unique Identifier : AIDSLINE MED/94314345; Schiller C; Spittler A; Willheim M; Szepfalusi Z; Agis H; Koller M; Peterlik M; Boltz-Nitulescu G; Institute of General and Experimental Pathology, University of; Vienna, Austria.; Suramin, a polyanionic and polycyclic compound, was initially used for the treatment of trypanosomiasis and onchocerciasis. In the last decade, it has been used in therapy of cancer and acquired immune deficiency syndrome (AIDS). The influence of suramin on the expression of various markers by human mononuclear phagoc
Epidemiologic strategies in psoriasis research.: Int J Dermatol. 1994 May;33(5):313-9. Unique Identifier : AIDSLINE MED/94314522; Nall L; Department of Dermatology, Stanford University School of; Medicine, California 94304.
More on extragenital HPV-16(+) lesions [letter; comment]: Int J Dermatol. 1994 May;33(5):390. Unique Identifier : AIDSLINE MED/94314540; Fader DJ
Novel retrovirus protease inhibitors, RPI-856 A, B, C and D, produced by Streptomyces sp. AL-322.: J Antibiot (Tokyo). 1994 May;47(5):557-65. Unique Identifier : AIDSLINE MED/94314632; Asano T; Matsuoka K; Hida T; Kobayashi M; Kitamura Y; Hayakawa T; Iinuma S; Kakinuma A; Kato K; Discovery Research Division, Takeda Chemical Industries, Ltd.,; Osaka, Japan.; Four kinds of retrovirus protease inhibitors (RPI-856 A, B, C and D) were isolated as white powder from the culture filtrate of a soil isolate, Streptomyces sp. AL-322 by column chromatography using Diaion HP-20, Sephadex LH-20, ODS reversed phase HPLC and SP-2SW io
Inhibitory effect of curromycin A and B on human immunodeficiency virus replication [letter]: J Antibiot (Tokyo). 1994 May;47(5):616-8. Unique Identifier : AIDSLINE MED/94314644; Nakamura M; Honma H; Kamada M; Ohno T; Kunimoto S; Ikeda Y; Kondo S; Takeuchi T
Idiopathic CD4+ T lymphocytopenia in a patient with mycosis fungoides [see comments]: J Am Acad Dermatol. 1994 Aug;31(2 Pt 1):275-6. Unique Identifier : AIDSLINE MED/94315082; Grossman D; Lewis DE; Ballas ZK; Duvic M; Department of Microbiology and Immunology, Baylor College of; Medicine, Houston, TX.
Lymphocyte populations associated with exaggerated insect bite reaction [letter; comment]: J Am Acad Dermatol. 1994 Aug;31(2 Pt 1):298-9. Unique Identifier : AIDSLINE MED/94315093; Tokura Y
I'm a dentist and I'm HIV positive.: J Ala Dent Assoc. 1993 Fall;77(4):26-9. Unique Identifier : AIDSLINE MED/94315186; Byers MM
Managing occupational risks in the dental office: HIV and the dental professional.: J Am Dent Assoc. 1994 Jul;125(7):847-52. Unique Identifier : AIDSLINE MED/94315207; Beekmann SE; Henderson DK; Hospital Epidemiology Service, National Institutes of Health,; Bethesda, Md. 20892.; Despite universal precautions, work behavior modifications and technological advances, health care workers continue to experience occupational exposures to HIV and other bloodborne pathogens. Although the risk for infection is low when compared with other bloodborne pathogens, 39 documented cases of HIV seroconversion
[Reflections on 10 years of medically induced abortions in Ille-et-Vilaine]: J Gynecol Obstet Biol Reprod (Paris). 1994;23(2):157-65. Unique Identifier : AIDSLINE MED/94315248; Schneider S; Roussey M; Odent S; Debroise C; Poulain P; Jouan H; Milon J; Betremieux P; Journel H; Le Mee F; et al; Service de Pediatrie-Genetique Medicale, CHU Pontchaillou,; Rennes.; The medical files of 532 patients who underwent medically induced abortion over a 10-year period (1982-1991) in the French department of Ille-et-Vilaine were studied in order to evaluate the indications and outcomes. Among the patients, 358 resided in the department (67%). Comparatively with the number of births durin
The acquired immune deficiency syndrome: an overview for the emergency physician, Part 1.: J Emerg Med. 1994 May-Jun;12(3):375-84. Unique Identifier : AIDSLINE MED/94315271; Guss DA; University of California, San Diego Medical Center 92103-8676.; The acquired immune deficiency syndrome (AIDS) was recognized as a distinct entity in 1981. It began as a medical curiosity affecting only several dozen individuals in a restricted segment of the U.S. population. In the 12 years since its description, AIDS has become a pandemic affecting tens of millions with cases re
Intermediates in the oxidation of a dihydropyridine derivative of AZT related to AIDS dementia, studied by nanosecond laser photolysis.: J Photochem Photobiol B. 1994 May;23(2-3):207-11. Unique Identifier : AIDSLINE MED/94315484; Lindqvist L; Czochralska B; Kawczynski W; Laboratoire de Photophysique Moleculaire, Universite de; Paris-Sud, Orsay, France.; Radicals of the AZT derivative 5 -(1,4-dihydro-1-methyl-3-pyridinylcarbonyl)-3 -azido-2 ,3 -dide- o xythymidine) were obtained on exposure of this compound in alkaline aqueous solution to pulsed laser emission of lambda = 355 nm and pulsewidth 2 ns FW
Three open-label studies of oral interferon alpha in the treatment of HIV disease.: J Natl Med Assoc. 1994 Apr;86(4):257-62. Unique Identifier : AIDSLINE MED/94315636; Jordan WC; Oasis (AIDS) Clinic, Martin Luther King, Jr General Hospital,; Drew University of Medicine and Science, Los Angeles, California.; Three open-label studies were conducted in which natural human interferon-alpha (nHuIFN-alpha) was given orally to human immunodeficiency virus (HIV)-infected patients at a daily dosage of 150 IU for 12 months in an attempt to assess the effects of this treatment on their CD4+ cell counts. In the first study, 110 pati
A piece of my mind. The little picture.: JAMA. 1994 Aug 10;272(6):417. Unique Identifier : AIDSLINE MED/94315701; Gelman B
New AIDS spread, old issues surface [news]: JAMA. 1994 Aug 10;272(6):419. Unique Identifier : AIDSLINE MED/94315702; Cotton P
US, French AIDS test patent rights renegotiated [news]: JAMA. 1994 Aug 10;272(6):420, 421. Unique Identifier : AIDSLINE MED/94315703; Marwick C
From the Institute of Medicine.: JAMA. 1994 Aug 10;272(6):423. Unique Identifier : AIDSLINE MED/94315705; Hardy LM; Haynes BF; Volberding PA
HIV infection in vaccinated volunteers [letter]: JAMA. 1994 Aug 10;272(6):431. Unique Identifier : AIDSLINE MED/94315711; Belshe RB; Bolognesi DP; Clements ML; Corey L; Dolin R; Mestecky J; Mulligan M; Stablein D; Wright P
Regulating syringe exchange programs: a cautionary note [letter]: JAMA. 1994 Aug 10;272(6):431-2. Unique Identifier : AIDSLINE MED/94315712; Des Jarlais DC; Paone D; Friedman SR; Peyser N; Newman RG
HIV seroconversion among high-risk women in New York City [letter]: JAMA. 1994 Aug 10;272(6):432-3. Unique Identifier : AIDSLINE MED/94315713; Weedon J; Thomas P
Female-to-female sexual contact and HIV transmission [letter]: JAMA. 1994 Aug 10;272(6):433. Unique Identifier : AIDSLINE MED/94315714; Chu SY; Conti L; Schable BA; Diaz T
Transmission of zidovudine-resistant HIV during a bloody fight [letter]: JAMA. 1994 Aug 10;272(6):433-4. Unique Identifier : AIDSLINE MED/94315715; Ippolito G; Del Poggio P; Arici C; Gregis GP; Antonelli G; Riva E; Dianzani F
Potential cost of screening surgeons for HIV [letter; comment]: JAMA. 1994 Aug 10;272(6):434-5. Unique Identifier : AIDSLINE MED/94315717; Roizen MF; Foss J; Mantha S
Limited effects of HIV counseling and testing for women. A prospective study of behavioral and psychological consequences.: JAMA. 1994 Aug 10;272(6):443-8. Unique Identifier : AIDSLINE MED/94315722; Ickovics JR; Morrill AC; Beren SE; Walsh U; Rodin J; Department of Internal Medicine, Yale University School of; Medicine, New Haven, CT 06520-8025.; OBJECTIVES--To assess the consequences of human immunodeficiency virus (HIV) counseling and testing for seronegative women in terms of sexual behavior and psychological outcomes. DESIGN--The design is prospective and longitudinal, using repeated measures. Participants were interviewed at recruitment, 2 weeks later (wh
Seroprevalence of HIV and risk behaviors among young homosexual and bisexual men. The San Francisco/Berkeley Young Men's Survey.: JAMA. 1994 Aug 10;272(6):449-54. Unique Identifier : AIDSLINE MED/94315723; Lemp GF; Hirozawa AM; Givertz D; Nieri GN; Anderson L; Lindegren ML; Janssen RS; Katz M; AIDS Office, San Francisco Department of Public Health, CA 94102.; OBJECTIVE--To estimate the prevalence of human immunodeficiency virus (HIV) infection and risk behaviors among young homosexual and bisexual men sampled from public venues in San Francisco and Berkeley, Calif. DESIGN--A survey of 425 young homosexual and bisexual men sampled from 26 locations during 1992 and 1993. Par
HIV and tuberculosis infection in San Francisco's homeless adults. Prevalence and risk factors in a representative sample [see comments]: JAMA. 1994 Aug 10;272(6):455-61. Unique Identifier : AIDSLINE MED/94315724; Zolopa AR; Hahn JA; Gorter R; Miranda J; Wlodarczyk D; Peterson J; Pilote L; Moss AR; Department of Epidemiology and Biostatistics, University of; California-San Francisco 94143-1347.; OBJECTIVE--To determine the prevalence and risk factors for human immunodeficiency virus (HIV) and tuberculosis (TB) infection and investigate the relationship between these two infections in homeless adults. DESIGN--Cross-sectional study. SETTING--Inner-city shelters and free meal programs. PARTICIPANTS--A representa
Prospective comparison of mother-to-child transmission of HIV-1 and HIV-2 in Abidjan, Ivory Coast [see comments] [published erratum appears in JAMA 1994 Nov 16;272(19):1482]: JAMA. 1994 Aug 10;272(6):462-6. Unique Identifier : AIDSLINE MED/94315725; Adjorlolo-Johnson G; De Cock KM; Ekpini E; Vetter KM; Sibailly T; Brattegaard K; Yavo D; Doorly R; Whitaker JP; Kestens L; et al; Projet RETRO-CI, Abidjan, Ivory Coast.; OBJECTIVE--To compare mother-to-child transmission of human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2, respectively) and to assess the impact of maternal HIV-1 and HIV-2 infections on child survival. DESIGN--Prospective cohort study. SETTING--Maternal and child health center in a lower socioeconomic class
Features of HIV-1 that could influence maternal-child transmission [see comments]: JAMA. 1994 Aug 10;272(6):467-74. Unique Identifier : AIDSLINE MED/94315726; Kliks SC; Wara DW; Landers DV; Levy JA; Cancer Research Institute, University of California-San; Francisco.; OBJECTIVE--To evaluate the biological and serological properties of the human immunodeficiency virus type 1 (HIV-1) for factors potentially involved in the mother-to-child transmission of HIV-1. DESIGN--Isolates of HIV-1 were recovered from the blood of 12 of 44 nontransmitting mothers and six of eight transmitting mo
The public health implications of AIDS research in Africa.: JAMA. 1994 Aug 10;272(6):481-6. Unique Identifier : AIDSLINE MED/94315728; De Cock KM; Ekpini E; Gnaore E; Kadio A; Gayle HD; Projet RETRO-CI, Abidjan, Ivory Coast.; The human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) epidemic has led to greatly increased international collaboration for medical research, mainly epidemiologic in nature, in Africa. Greater understanding of HIV/AIDS has resulted, and considerable training and technology transfer have occurr
Immunological and virological clues for mother-to-child transmission of HIV-1 and HIV-2 [editorial; comment]: JAMA. 1994 Aug 10;272(6):487-8. Unique Identifier : AIDSLINE MED/94315729; Douglas SD
AIDS vaccines. Are we ready for human efficacy trials? [editorial; comment]: JAMA. 1994 Aug 10;272(6):488-9. Unique Identifier : AIDSLINE MED/94315730; Mascola JR; McNeil JG; Burke DS
[A case of adult T cell leukemia complicated with strongyloidiasis and amplification of pneumocystis carinii DNA in bronchoalveolar lavage fluid]: Nippon Kyobu Shikkan Gakkai Zasshi. 1994 Apr;32(4):348-52. Unique Identifier : AIDSLINE MED/94315792; Adachi N; Ohta K; Negoro N; Kurihara N; Takeda T; First Department of Internal Medicine, Osaka City University; Medical School, Japan.; The patient was a 75-year-old male, who simultaneously showed symptoms of bacterial meningitis during steroid treatment for erythroderma and symptoms of respiratory failure. Based on ground-glass shadows in both lungs on chest X ray, bronchoalveolar lavage (BAL) was carried out and strongyloides was detected. In addit
[A case of bronchiectasis accompanied by ulcerative colitis (UC) and HTLV-1 associated myelopathy (HAM)]: Nippon Kyobu Shikkan Gakkai Zasshi. 1994 Apr;32(4):358-63. Unique Identifier : AIDSLINE MED/94315794; Suzuki I; Watanabe N; Suzuki J; Yamaguchi E; Munakata M; Fujita M; First Department of Medicine, Hokkaido University School of; Medicine, Sapporo, Japan.; We report a case of bronchiectasis with marked thickening of the respiratory tract wall occurring in a 37-year-old man with UC and HAM. He was diagnosed as UC at age 20. HTLV-1 was presumably transmitted to this patient by means of a blood transfusion he received at around age 30. On admission, chest X-ray films, tomo
Experimental murine pulmonary cryptococcosis. Differences in pulmonary inflammation and lymphocyte recruitment induced by two encapsulated strains of Cryptococcus neoformans.: Lab Invest. 1994 Jul;71(1):113-26. Unique Identifier : AIDSLINE MED/94315861; Curtis JL; Huffnagle GB; Chen GH; Warnock ML; Gyetko MR; McDonald RA; Scott PJ; Toews GB; Pulmonary Section, Department of Veterans Affairs Medical Center,; Ann Arbor, MI.; BACKGROUND: Cryptococcus neoformans, the most common cause of lethal mycosis in AIDS, usually causes only subclinical pneumonitis in normal hosts. However, cryptococcosis can induce various pulmonary inflammatory reactions, and pulmonary cellular immunity is postulated to prevent dissemination. We hypothesized that cr
Cytomegalovirus infection of human retinal tissue: an in vivo model.: Lab Invest. 1994 Jul;71(1):141-8. Unique Identifier : AIDSLINE MED/94315864; DiLoreto D Jr; Epstein LG; Lazar ES; Britt WJ; del Cerro M; Department of Neurobiology and Anatomy, University of Rochester; School of Medicine, New York.; BACKGROUND: Cytomegalovirus ( CMV ) retinitis is a common, devastating complication of AIDS. Strict host specificity of human CMV (HCMV), has limited the study of the virus. The purpose of this research was to create a model that allowed the in vivo infection of h
[Replication indexes of the human immunodeficiency virus: predictive value of viral culture and blood antigens]: Med Clin (Barc). 1994 May 21;102(19):725-30. Unique Identifier : AIDSLINE MED/94315956; Carton JA; Melon S; Maradona JA; de Ona M; Asensi V; Martinez A; Carcaba V; Servicio de Medicina Interna, Enfermedades Infecciosas, Hospital; Central de Asturias (Hospital Nuestra Senora de Covadonga),; Universidad de Oviedo.; BACKGROUND: To investigate the relation between markers of load and replication of the HIV [viral culture in plasma and in mononuclear cells of peripheral blood (MCPB) and antigen p24 (p24Ag) with the number of CD4+ cells and the prognosis of the patients. METHODS: A retrospective study was performed in 188 patients w
[Mycobacterium scrofulaceum and Mycobacterium tuberculosis coinfection in an AIDS patient (letter)]: Med Clin (Barc). 1994 May 28;102(20):799. Unique Identifier : AIDSLINE MED/94315981; Dronda F; Fernandez E; Chaves F
The current spectrum of Staphylococcus aureus infection in a tertiary care hospital.: Medicine (Baltimore). 1994 Jul;73(4):186-208. Unique Identifier : AIDSLINE MED/94316015; Musher DM; Lamm N; Darouiche RO; Young EJ; Hamill RJ; Landon GC; Medical Service, Veterans Affairs Medical Center, Houston, TX; 77030.; Staphylococcus aureus remains a prominent cause of community- and hospital-acquired infection. This study reviewed 162 cases of S. aureus infection occurring in 120 adults who were hospitalized at a Veterans Affairs Medical Center and referred for consultation to the Infectious Disease Service. There were 37 cases of
[Isosporiasis and AIDS]: Med Parazitol (Mosk). 1993 May-Jun;(3):45-8. Unique Identifier : AIDSLINE MED/94316098; Chaika NA
[Current concepts of the epidemiology of cryptosporidiosis (comment)]: Med Parazitol (Mosk). 1993 May-Jun;(3):49-54. Unique Identifier : AIDSLINE MED/94316099; Lavdovskaia MV; Lysenko AIa
Use of HIV test results banned [news]: Minn Med. 1994 Jun;77(6):38. Unique Identifier : AIDSLINE MED/94316109
AIDS increasing child mortality [news]: Minn Med. 1994 Jun;77(6):56. Unique Identifier : AIDSLINE MED/94316114
Skeletal muscle involvement in tropical spastic paraparesis/HTLV-1-associated myelopathy.: Muscle Nerve. 1994 Aug;17(8):923-30. Unique Identifier : AIDSLINE MED/94316236; Gabbai AA; Wiley CA; Oliveira AS; Smith R; Schmidt B; Nobrega JA; Bordin JO; Roman GC; Department of Neurology, Escola Paulista de Medicina, Brazil.; The frequency of muscle involvement in TSP/HAM is not known, nor is the precise role that HTLV-1 and the diverse cytokines play in the genesis of HTLV-1-associated diseases. In order to better define the frequency and characteristics of the skeletal muscle involvement in TSP/HAM, we studied 11 affected patients. EMG w
HIV-associated periodontal disease.: Northwest Dent. 1993 Sep-Oct;72(5):25-8. Unique Identifier : AIDSLINE MED/94316477; Cobb CM; School of Dentistry, University of Missouri-Kansas City; 64108-2795.
Methylphosphonate mapping of phosphate contacts critical for RNA recognition by the human immunodeficiency virus tat and rev proteins.: Nucleic Acids Res. 1994 Jul 11;22(13):2592-600. Unique Identifier : AIDSLINE MED/94316502; Pritchard CE; Grasby JA; Hamy F; Zacharek AM; Singh M; Karn J; Gait MJ; MRC Laboratory of Molecular Biology, Cambridge, UK.; The HIV-1 regulatory proteins tat and rev are both RNA binding proteins which recognize sequences in duplex RNA which are close to structural distortions. Here we identify phosphate contacts which are critical for each binding reaction by use of a new method. Model RNA binding sites are constructed carrying substituti
The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes.: Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):6992-6. Unique Identifier : AIDSLINE MED/94316624; von Schwedler U; Kornbluth RS; Trono D; Infectious Disease Laboratory, Salk Institute for Biological; Studies, La Jolla, CA 92037-1099.; Lentiviruses, including human immunodeficiency virus type 1 (HIV-1), are unusual among retroviruses in their ability to infect nondividing cells. The matrix proteins of several lentiviruses contain a short stretch of amino acids reminiscent of known nuclear localization signals. In HIV-1, this motif has been shown to
Cell-surface receptors for gibbon ape leukemia virus and amphotropic murine retrovirus are inducible sodium-dependent phosphate symporters.: Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7071-5. Unique Identifier : AIDSLINE MED/94316639; Kavanaugh MP; Miller DG; Zhang W; Law W; Kozak SL; Kabat D; Miller AD; Vollum Institute for Advanced Biomedical Research, Oregon Health; Sciences University, Portland 97201.; Cell surface receptors for gibbon ape leukemia virus (Glvr-1) and murine amphotropic retrovirus (Ram-1) are distinct but related proteins having multiple membrane-spanning regions. Distant homology with a putative phosphate permease of Neurospora crassa suggested that these receptors might serve transport functions. B
The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.: Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7311-5. Unique Identifier : AIDSLINE MED/94316685; Heinzinger NK; Bukinsky MI; Haggerty SA; Ragland AM; Kewalramani V; Lee MA; Gendelman HE; Ratner L; Stevenson M; Emerman M; Department of Pathology and Microbiology, University of Nebraska; Medical Center, Omaha 68198-5120.; The replication of human immunodeficiency virus type 1 (HIV-1) in nondividing host cells such as those of macrophage lineage is an important feature of AIDS pathogenesis. The pattern of HIV-1 replication is dictated, in part, by the nucleophilic property of the viral gag matrix (MA) protein, a component of the viral p
A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro.: Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7316-20. Unique Identifier : AIDSLINE MED/94316686; Ellison V; Brown PO; Department of Biochemistry, Stanford University, CA 94305-5428.; Retroviral replication depends on integration of the viral genome into a chromosome of the host cell. The steps in this process are orchestrated in vivo by a large nucleoprotein complex and are catalyzed by the retroviral enzyme integrase. Several biochemical properties of the in vivo nucleoprotein complex were reprod
A state program for postpartum HIV counseling and testing.: Public Health Rep. 1994 Jul-Aug;109(4):521-9. Unique Identifier : AIDSLINE MED/94316769; Holman S; Sorin MD; Crossette J; LaChance-McCullough ML; New York State Department of Health's, AIDS Institute, NY 10001.; The New York State Department of Health began its Obstetrical HIV Counseling/Testing/Care Initiative in 1989. The objective of the initiative was to expand the availability of and access to human immunodeficiency virus (HIV) infection counseling and voluntary testing in the postpartum setting. Programs have been initi
Prevalence of illicit drugs detected in the urine of women of childbearing age in Alabama public health clinics.: Public Health Rep. 1994 Jul-Aug;109(4):530-8. Unique Identifier : AIDSLINE MED/94316770; Pegues DA; Engelgau MM; Woernle CH; Division of Field Epidemiology, Centers for Disease Control and; Prevention (CDC), Atlanta, GA.; Each year, it is estimated that from 350,000 to 739,000 U.S. infants are exposed in utero to one or more illicit drugs. To estimate the prevalence of and risk factors for illicit drug use by women of childbearing age in Alabama, during 2 months in 1991 the authors collected patient-reported histories, clinical histori
Sexual risk behavior of incarcerated, drug-using women, 1992.: Public Health Rep. 1994 Jul-Aug;109(4):539-47. Unique Identifier : AIDSLINE MED/94316771; Schilling R; el-Bassel N; Ivanoff A; Gilbert L; Su KH; Safyer SM; School of Social Work, Columbia University, New York City, NY; 10025.; In this study, sexual risk behavior of 104 incarcerated female drug users is examined. Findings demonstrate that incarcerated women who use drugs are at high risk for human immunodeficiency virus (HIV) infection because of their behavior prior to arrest. During the month prior to arrest, the majority of respondents we
The impact of providing incentives for attendance at AIDS prevention sessions [see comments]: Public Health Rep. 1994 Jul-Aug;109(4):548-54. Unique Identifier : AIDSLINE MED/94316772; Deren S; Stephens R; Davis WR; Feucht TE; Tortu S; Institute for AIDS Research, National Development and Research; Institutes, Inc., New York City.; The research literature on AIDS prevention efforts contains many reports on the impact of intervention sessions. Little information is available, however, on the success of various strategies to recruit clients to attend these sessions. An assessment of the comparative impact of money and other types of incentives on
Building a community-based consortium for AIDS patient services.: Public Health Rep. 1994 Jul-Aug;109(4):555-62. Unique Identifier : AIDSLINE MED/94316773; Myers AM; Pfeiffle P; Hinsdale K; City and County of Denver, Department of Health and Hospitals, CO; 80204.; The authors describe a 3-year effort by a public health care system in a large metropolitan area to obtain Federal funds for treating patients with acquired immunodeficiency syndrome (AIDS). During that process, program planners moved incrementally from proposing an exclusively medical model to one emphasizing the act
Risk behavior for HIV transmission among gay men surveyed in Seattle bars.: Public Health Rep. 1994 Jul-Aug;109(4):563-6. Unique Identifier : AIDSLINE MED/94316774; Steiner S; Lemke AL; Roffman RA; Innovative Programs Research Group (IPRG), Seattle, WA.; Men attending four Seattle gay bars were asked to complete a self-administered questionnaire including measures of sexual behavior, perceptions of peer norms in the area of sexual safety, personal human immunodeficiency virus (HIV) risk estimate, and knowledge and use of a variety of acquired immunodeficiency syndrome
WHO announces new TB control initiative [news]: Public Health Rep. 1994 Jul-Aug;109(4):589-90. Unique Identifier : AIDSLINE MED/94316779
[Atypical radiological images in Pneumocystis carinii infection in HIV-positive patients]: Radiol Med (Torino). 1994 Jun;87(6):763-7. Unique Identifier : AIDSLINE MED/94316852; Cornalba GP; Mariani P; Colombo E; Bianco R; Vona S; Servizio di Radiodiagnostica, Ospedale Luigi Sacco, Milano.; To assess the prevalence of atypical PCP patterns in AIDS patients, the chest films of 300 patients with clinical and laboratory diagnosis of PCP were reviewed. We considered as atypical patterns the finding of an asymmetric lesion, the involvement of apical regions, pleural effusion, hilar and/or mediastinal lymphade
[The percutaneous treatment of purulent intrathoracic fluid collections in HIV+ patients]: Radiol Med (Torino). 1994 Jun;87(6):833-6. Unique Identifier : AIDSLINE MED/94316862; Ambrogi C; Cianni R; Perona F; Barile A; Ferro C; Servizio di Radiologia, Ospedale S. M. Goretti, Latina.; Eighteen HIV+ patients with purulent fluid intrathoracic collections (16 pleural empyemas and 2 lung abscesses) and persistent sepsis were treated with percutaneous drainage; all patients had received antibiotics for 5-7 days at least. Empyemas and lung abscesses were cured (according to clinical and radiographic crit
[Treatment with clarithromycin of 173 HIV+ patients with disseminated Mycobacterium avium intracellulare infection]: Rev Mal Respir. 1994;11(3):271-6. Unique Identifier : AIDSLINE MED/94316918; Dautzenberg B; Saint-Marc T; Durant J; Reynes J; Meyohas MC; Legrand MF; Truffot C; Chauvin JP; Service de Pneumologie, Groupe Hospitalier Pitie-Salpetriere,; Paris.; No treatment was established for disseminated M. avium intracellulare (MAC) infection, a common disease of end stage of AIDS. An open study was conducted to assess in 173 AIDS patients, the activity of clarithromycin. Initial bacteriologic eradication from blood was observed in 136/147 evaluable patients (93%). Acquir
[Pulmonary malacoplakia and Rhodococcus equi pneumonia in a patient infected with the human immunodeficiency virus. A case report with review of the literature]: Rev Mal Respir. 1994;11(3):301-3. Unique Identifier : AIDSLINE MED/94316925; Lemmens B; Besnier JM; Diot P; Fetissof F; Anthonioz P; Cattier B; Choutet P; Service de Pneumologie, CHU Tours.; We report a case of pulmonary malakoplakia in a patient suffering from AIDS secondary to a Rhodococcus equi pneumonia. The association between these two pathologies only occurring in the immunodepressed does not seen fortuitous. Deficiency in cellular immunity and macrophage cellular activity as well as failure of int
[HIV and lung interactions]: Rev Mal Respir. 1994;11(3):313-5. Unique Identifier : AIDSLINE MED/94316928; Cadranel J; Israel-Biet D; Mayaud C; Service de Pneumologie et de Reanimation Respiratoire, Hopital; Tenon, Paris.
[Attrition, dentin apposition and protein synthesis in the pulp and desmodont of young and old rats]: Schweiz Monatsschr Zahnmed. 1994;104(6):731-9. Unique Identifier : AIDSLINE MED/94316984; Schroeder HE; Munzel-Pedrazzoli S; Abteilung fur Orale Strukturbiologie, Universitat Zurich.; Occlusal attrition and responsive adaptations in the pulp-dentinal unit are still problematic. In this study, up to 2 years-old rats were used to measure the amount of occlusal attrition, of dentin apposition and of the incorporation of 3H-proline into the pulpal and periodontal ligament tissues. Two to four SIV-rats
Dissent in science: styles of scientific practice and the controversy over the cause of AIDS.: Soc Sci Med. 1994 Apr;38(8):1017-36. Unique Identifier : AIDSLINE MED/94317013; Fujimura JH; Chou DY; Department of Anthropology, Stanford University, CA 94305.; In this paper, we use a scientific controversy, and the efforts to legitimize and undermine a theory, to examine the co-production of facts and the rules for verifying facts over time. We discuss these processes in terms of what we call styles of scientific practice. In contrast to the focus of idealist philosophers
The social impact of HIV infection on women in Kigali, Rwanda: a prospective study.: Soc Sci Med. 1994 Apr;38(8):1047-53. Unique Identifier : AIDSLINE MED/94317015; Keogh P; Allen S; Almedal C; Temahagili B; Department of Pathology, University of California, San Francisco; 94105.; In Rwanda , a central African country, the prevalence of HIV infection now exceeds 30% in urban adults. This study identifies the social services and counseling needs of women who are already infected with the HIV virus, the outcome after disclosure of the woman s HIV test result to
Using STD occurrence to monitor AIDS prevention.: Soc Sci Med. 1994 Apr;38(8):1153-65. Unique Identifier : AIDSLINE MED/94317023; Renton AM; Whitaker L; Academic Department of Public Health, St Mary's Hospital Medical; School, London, U.K.; Monitoring the effects of AIDS prevention programmes is increasingly important but methodologically difficult. The use of surveillance derived measures of the occurrence of sexually transmitted diseases as indicators of high risk sexual behaviour, or of HIV incidence, has been widely recognized as a possible approach.
A meta-analysis of condom effectiveness in reducing sexually transmitted HIV [letter; comment]: Soc Sci Med. 1994 Apr;38(8):1169-70. Unique Identifier : AIDSLINE MED/94317024; Warner DL; Hatcher RA
AIDS sufferers as reservoirs of secondary diseases [letter]: S Afr Med J. 1994 Feb;84(2):110. Unique Identifier : AIDSLINE MED/94317045; Markus MB
[The relationship between tuberculosis, vitamin D, potassium and AIDS. A message for South Africa?]: S Afr Med J. 1994 Feb;84(2):79-82. Unique Identifier : AIDSLINE MED/94317066; Lochner JD; Schneider DJ; Departement Geneeskundige Fisiologie en Biochemie, Universiteit; van Stellenbosch, Tygerberg.; The converging epidemics of tuberculosis and acquired immunodeficiency syndrome (AIDS) in the RSA and their expected catastrophic interaction afford an ideal opportunity for well-planned and essential research by clinicians, molecular biologists, epidemiologists and other health workers. The enigmatic relationship bet
Trends in sexual behavior. Analyse des Comportements Sexuels en France Investigators.: Sex Transm Dis. 1994 Mar-Apr;21(2 Suppl):S14-8. Unique Identifier : AIDSLINE MED/94317075; Spira A; Bajos N; Ducot B; Hopital de Bicetre, France.; The definition of strategies for preventing STD and AIDS requires a better knowledge of sexual behavior in the general population and in specific subgroups of the population. Surveys have been undertaken in different countries to provide such information, and they allow to draw some general conclusions. Even if there
Recent advances in diagnosis of sexually transmitted diseases.: Sex Transm Dis. 1994 Mar-Apr;21(2 Suppl):S19-27. Unique Identifier : AIDSLINE MED/94317076; Quinn TC; Division of Infectious Diseases, Johns Hopkins University School; of Medicine, Baltimore, Maryland 21205.; In an effort to better diagnose, treat, and control sexually transmitted diseases (STD), a number of new diagnostic assays using molecular techniques have been developed. By incorporating molecular amplification, the sensitivity for detecting sexually transmitted infections has become markedly enhanced, and organisms
Human immunodeficiency virus infection and pregnancy.: Sex Transm Dis. 1994 Mar-Apr;21(2 Suppl):S28-31. Unique Identifier : AIDSLINE MED/94317077; Peckham CS; Division of Public Health, Institute of Child Health, London,; England.; Vertical transmission from mother-to-child is the main mode of acquisition of HIV infection in children. Infection may be acquired before, during, or after birth, but the relative contribution of each of these routes remains unknown. Estimates of the rate of vertical transmission range from 15% to 39%, and the rate is
The current trend in genital herpes. Progress in prevention.: Sex Transm Dis. 1994 Mar-Apr;21(2 Suppl):S38-44. Unique Identifier : AIDSLINE MED/94317079; Corey L; Department of Laboratory Medicine, University of Washington,; Seattle 98144.; Recent serosurveys indicate that the prevalence of genital herpes has continued to increase even during the decade of HIV. Much of this continued transmission is due to the difficulty of identifying the subclinical carrier of HSV-2. The development of serologic assays that accur
Epidemiology and control of sexually transmitted diseases in developing countries.: Sex Transm Dis. 1994 Mar-Apr;21(2 Suppl):S45-50. Unique Identifier : AIDSLINE MED/94317080; Laga M; Institute of Tropical Medicine, Antwerp, Belgium.; The knowledge of the epidemiology of STD in the developing world had increased considerably during the last decade. This better understanding combined with the emergence of the epidemic of a new fatal STD (HIV) encouraged health planners to define appropriate effective and feasible STD control strategies. Major progre
Epidemiology of sexually transmitted diseases.: Sex Transm Dis. 1994 Mar-Apr;21(2 Suppl):S51-2. Unique Identifier : AIDSLINE MED/94317081; Coutinho RA; Department of Public Health and Environment, Municipal Health; Service, Amsterdam, The Netherlands.; The epidemiologic patterns of sexually transmitted diseases (STD) in developed countries are changing, but the picture is different in Europe and the United States . General trends are summarized.
Sexually transmitted disease and human immunodeficiency virus. Is everyone at risk and does everyone have to pay?: Sex Transm Dis. 1994 Mar-Apr;21(2 Suppl):S53-4. Unique Identifier : AIDSLINE MED/94317082; Padian N; Aral SO; Holmes KK; University of California, San Francisco.; The pattern of disease within populations depends on the complex interaction between individuals. For example, the linking of individuals to form social and sexual networks affects disease incidence and prevalence. As described by Potterat, the formation of these networks results in various patterns of disease spread.
Sexually transmitted disease prevention approaches that work. Interventions to reduce risk behavior among individuals, groups, and communities.: Sex Transm Dis. 1994 Mar-Apr;21(2 Suppl):S73-5. Unique Identifier : AIDSLINE MED/94317087; Kelly JA; Department of Psychiatry and Mental Health Sciences, Medical; College of Wisconsin, Milwaukee 53226.; Behavior change remains the only available means to curtail new HIV infections. Although much remains to be learned about the effectiveness of different prevention strategies, there has already been evidence that both face-to-face interventions focused on individuals and community-level interventions focused on vulner
Recent changes in the epidemiology of genital ulcer disease in the United States. The crack cocaine connection.: Sex Transm Dis. 1994 Mar-Apr;21(2 Suppl):S76-80. Unique Identifier : AIDSLINE MED/94317088; Martin DH; DiCarlo RP; Louisiana State University School of Medicine, New Orleans.; The incidence of syphilis and chancroid began to increase in the United States among heterosexuals in the mid-1980s, with most cases reported among minorities living in Eastern cities and in the South. A number of studies have established a link between increasing syphilis incidence ra
Periodontal pocketing in HIV-associated periodontitis.: Spec Care Dentist. 1993 Nov-Dec;13(6):236-40. Unique Identifier : AIDSLINE MED/94317096; Epstein JB; Leziy S; Ransier A; Division of Oral Medicine and Clinical Dentistry, Vancouver; General Hospital, Canada.; Gingival and periodontal involvement has been described in individuals with Human Immunodeficiency Virus (HIV) infection. The manifestations often include erythematous gingivitis, necrotizing gingivitis, and periodontal involvement characterized by rampant loss of bone and soft tissue, resulting in recession without t
A field evaluation of the polymerase chain reaction procedure for the detection of bovine leukaemia virus proviral DNA in cattle.: Vet Microbiol. 1994 Apr;39(3-4):313-21. Unique Identifier : AIDSLINE MED/94317281; Eaves FW; Molloy JB; Dimmock CK; Eaves LE; Queensland Department of Primary Industries, Animal Research; Institute, Australia.; A polymerase chain reaction (PCR) procedure that detects proviral bovine leukaemia virus (BLV) in peripheral blood mononuclear cell DNA was evaluated. Blood samples from all animals (164) in a commercial dairy herd with a 30% prevalence of BLV infection, and from 194 animals from BLV free herds were tested. The absenc
Control of bovine leukaemia virus transmission by selective culling of infected cattle on the basis of viral antigen expression in lymphocyte cultures.: Vet Microbiol. 1994 Apr;39(3-4):323-33. Unique Identifier : AIDSLINE MED/94317282; Molloy JB; Dimmock CK; Eaves FW; Bruyeres AG; Cowley JA; Ward WH; Queensland Department of Primary Industries, Animal Research; Institute, Australia.; The use of viral antigen expression in lymphocyte cultures to prioritize the culling of bovine leukaemia virus (BLV) infected cattle was evaluated as a means of controlling the spread of infection in heavily infected herds. Selective culling was implemented in five commercial dairy herds containing between 126 and 304
Effect of chronic feline immunodeficiency virus infection on experimental feline calicivirus-induced disease.: Vet Microbiol. 1994 Apr;39(3-4):335-51. Unique Identifier : AIDSLINE MED/94317283; Reubel GH; George JW; Higgins J; Pedersen NC; Department of Medicine, School of Veterinary Medicine, University; of California, Davis 95616.; Acute feline calicivirus (FCV) infection caused a more severe disease in chronically feline immunodeficiency virus (FIV) infected than in non-FIV infected cats. FIV infected cats shed significantly higher amounts of FCV through their saliva after FCV challenge than the non-FIV infected cats. However, there was no diff
A temporal study of RNAs produced in maedi-visna virus infection of choroid plexus cells.: Vet Microbiol. 1994 Apr;39(3-4):369-78. Unique Identifier : AIDSLINE MED/94317286; Sargan DR; Roy DJ; Dalziel RG; Watt NJ; McConnell I; Department of Veterinary Pathology, University of Edinburgh,; Summerhall, UK.; We have examined the types and cellular distribution of transcripts of maedi-visna virus during infection of choroid plexus fibroblasts. Early in infection (19 hours post infection) only small spliced transcripts are found in the cytoplasm. Little virus specific RNA is detected in the nucleus at this stage. Later in i
Seroepidemiological and clinical survey of feline immunodeficiency virus infection in northern Italy.: Vet Immunol Immunopathol. 1994 Apr;40(4):285-97. Unique Identifier : AIDSLINE MED/94317287; Peri EV; Ponti W; Dall'ara P; Rocchi M; Zecconi A; Bonizzi L; Istituto di Microbiologia e Immunologia Veterinaria, Universita; degli Studi di Milano, Italy.; Four hundred and thirty-nine feline serum samples from cats with different living conditions in the north of Italy were tested for antibodies to feline immunodeficiency virus (FIV) and for antigen of Feline Leukemia Virus by enzyme-linked immunosorbent assay. A Western blot techniqu
Cytologic diagnosis of extrapulmonary Pneumocystis carinii infection in pleural and ascitic fluid. Report of a case in a patient with the acquired immunodeficiency syndrome.: Acta Cytol. 1994 Jul-Aug;38(4):608-10. Unique Identifier : AIDSLINE MED/94317451; Peiro-Cabrera G; Lerma-Puertas E; Esteva de Llobet E; de las Heras-Duran P; Munoz-Anatol P; Carreras-Marcer A; Department of Pathology, Hospital de la Santa Creu i Sant Pau,; Autonomous University of Barcelona, Spain.; We present a case of an extrapulmonary Pneumocystis carinii infection in a human immunodeficiency virus-positive patient undergoing prophylactic treatment with pentamidine. The diagnosis was established in pleural and ascitic fluid, and the patient died before starting specific systemic treatment. We discuss the cytol
Rate of tuberculosis in children with HIV is very high [news]: Am Fam Physician. 1994 Aug;50(2):407. Unique Identifier : AIDSLINE MED/94317603
A comparison of male and female intravenous drug users' risk behaviors for HIV infection.: Am J Drug Alcohol Abuse. 1994;20(2):129-57. Unique Identifier : AIDSLINE MED/94317628; Freeman RC; Rodriguez GM; French JF; Data Analysis and Epidemiology Unit, Division of Alcoholism, Drug; Abuse, and Addiction Services, New Jersey State Department of; Health, Newark.; Despite the central role played by female intravenous drug users (IVDUs) in the worsening AIDS statistics of states in the northeastern United States , the relative paucity of research into the HIV risk behaviors--particularly risky needle practices--of female drug injections has left s
Langerhans cell histiocytosis: lack of a viral etiology.: Am J Hematol. 1994 Sep;47(1):16-20. Unique Identifier : AIDSLINE MED/94317638; McClain K; Jin H; Gresik V; Favara B; Baylor College of Medicine, Texas Children's Hospital, Houston; 77030.; Langerhans cell histiocytosis (LCH) is an enigmatic histiocytic proliferative disorder of unknown etiology that affects children primarily. We have investigated the possibility that viruses are etiological or that they have a triggering effect in LCH. Sensitive in situ hybridization and polymerase chain reaction (PCR)
Zidovudine reduces transmission of HIV from mother to infant, study shows [news]: Am J Hosp Pharm. 1994 May 1;51(9):1142. Unique Identifier : AIDSLINE MED/94317662
Emerging indications for octreotide therapy, Part 1.: Am J Hosp Pharm. 1994 May 1;51(9):1184-92. Unique Identifier : AIDSLINE MED/94317668; Mosdell KW; Visconti JA; Raabe College of Pharmacy, Ohio Northern University.; Possible new indications for the use of octreotide are discussed. In October 1988, octreotide received FDA-approved labeling for use in the management of carcinoid syndrome and vipomas. Since that time, research results and clinical experience have accumulated that suggest a potentially much broader therapeutic role f
Anti-neutrophil antibodies of the immunoglobulin M class in autoimmune neutropenia.: Am J Med Sci. 1994 Aug;308(2):102-5. Unique Identifier : AIDSLINE MED/94317680; Hartman KR; Department of Hematology, Walter Reed Army Institute of Research,; Washington, DC 20307-5100.; Anti-neutrophil antibodies of the immunoglobulin G (IgG) class have been implicated in the pathogenesis of autoimmune neutropenia, but few reports have described immunoglobulin M (IgM) anti-neutrophil antibodies. To investigate the prevalence of IgM anti-neutrophil antibodies, sera from 130 patients with possible auto
Why not include contact tracing in HIV prevention? [letter; comment]: Ann Intern Med. 1994 Sep 1;121(5):388-9. Unique Identifier : AIDSLINE MED/94317889; Harris CJ
Equal inhibition of the replication of human immunodeficiency virus in human T-cell culture by ddA bis(SATE)phosphotriester and 3'-azido-2',3'-dideoxythymidine.: Biochem Pharmacol. 1994 Jul 5;48(1):11-14. Unique Identifier : AIDSLINE MED/94318075; Perigaud C; Aubertin AM; Benzaria S; Pelicano H; Girardet JL; Maury G; Gosselin G; Kirn A; Imbach JL; Laboratoire de Chimie Bio-Organique, U.R.A. 488 du C.N.R.S.,; Universite de Montpellier II, France.; It is shown that ddA bis(SATE)phosphotriester is one of the most potent anti-HIV agents in cell culture. Compared with the parent nucleoside, ddA, an increase of 3 orders of magnitude was observed in the EC50, which makes this compound as active as AZT
Hepatitis C virus infection. Psychosocial impact similar to that of HIV infection [letter; comment]: BMJ. 1994 Jun 25;308(6945):1710. Unique Identifier : AIDSLINE MED/94297467; Neeleman J; Unwin C; Farrel M
The prozone phenomenon in syphilis associated with HIV infection [letter; comment]: Arch Intern Med. 1994 Jul 25;154(14):1643-4. Unique Identifier : AIDSLINE MED/94304306; Haslett P; Laverty M
Fluconazole-insensitive OPC in AIDS patients [letter; comment]: J Infect. 1994 Mar;28(2):223-7. Unique Identifier : AIDSLINE MED/94308581; Troke PF; Hitchcock CA
Smallpox and AIDS [letter; comment]: Can Med Assoc J. 1994 Aug 1;151(3):271. Unique Identifier : AIDSLINE MED/94313488; Hart JF
Cocaine and HIV prevalence in an alcohol treatment center [letter; comment]: JAMA. 1994 Aug 10;272(6):435. Unique Identifier : AIDSLINE MED/94315718; Epstein R
Resistance to murine acquired immunodeficiency syndrome (MAIDS) [letter; comment]: Science. 1994 Jul 8;265(5169):264. Unique Identifier : AIDSLINE MED/94294794; Gilmore GL
Differential CD4-dependent regulation of naive and memory CD4+ T cell adhesion is not related to differences in expression and function of CD4 and p56lck.: Int Immunol. 1994 Apr;6(4):551-9. Unique Identifier : AIDSLINE MED/94289336; Lecomte O; Hivroz C; Mazerolles F; Fischer A; INSERM U132, Hopital Necker-Enfants Malades, Paris, France.; We have previously reported that antigen-independent adhesion of CD45RO+ memory CD4+ T cells to B cells is negatively regulated by CD4-MHC class II interaction, whereas that of CD45RA+ naive CD4+ T cells is not. We have now found that both cross-linking of CD4 ligands [anti-CD4 mAbs, HIV gp160 (env) protein and a 12me
Defective protein tyrosine phosphorylation and altered levels of p59fyn and p56lck in CD4 T cells from HIV-1 infected patients.: Int Immunol. 1994 Apr;6(4):611-21. Unique Identifier : AIDSLINE MED/94289342; Cayota A; Vuillier F; Siciliano J; Dighiero G; Immunohematology and Immunopathology Unit, Institut Pasteur,; Paris, France.; Early in HIV infection, CD4+ lymphocytes exhibit the properties of an anergic state characterized by unresponsiveness to mitogens or to TCR stimulation and by defective IL-2 production. As tyrosine phosphorylation is the earliest of the biochemical events initiated by
Human T-cell leukemia virus type I tax induces intracellular adhesion molecule-1 expression in T cells [letter]: Blood. 1994 Jul 1;84(1):350-1. Unique Identifier : AIDSLINE MED/94289725; Mori N; Murakami S; Oda S; Eto S
Contribution of tuberculosis to slim disease in Africa [see comments]: BMJ. 1994 Jun 11;308(6943):1531-3. Unique Identifier : AIDSLINE MED/94290200; Lucas SB; De Cock KM; Hounnou A; Peacock C; Diomande M; Honde M; Beaumel A; Kestens L; Kadio A; Department of Histopathology, University College London Medical; School.; OBJECTIVES--To assess the contribution of tuberculosis to the aetiology of the HIV wasting syndrome (slim) in Africa, a condition usually considered an enteropathy. METHODS--Clinical examination and representative necropsy study of adult patients positive for HIV. SETTING--Hospital medical wards in Abidjan,
Antiproliferative factor against the human glioblastoma cell line T98G identified in culture supernatants of CD4+ cells from patients with HTLV-I-associated myelopathy.: J Neurol Sci. 1994 Apr;122(2):214-9. Unique Identifier : AIDSLINE MED/94293037; Nishiura Y; Nakamura T; Ichinose K; Nagasato K; Ohishi K; Watanabe H; Shirabe S; Tsujihata M; Nagataki S; First Department of Internal Medicine, Nagasaki University School; of Medicine, Japan.; We investigated culture supernatants of peripheral blood mononuclear cells (MNC) derived from patients with human T-lymphotropic virus type I (HTLV-I)-associated myelopathy (HAM) for antiproliferative activity against the human glioblastoma cell line T98G. When T98G cells were cultured with condition medium containingt
Quantifying HIV-1 proviral DNA using the polymerase chain reaction on cerebrospinal fluid and blood of seropositive individuals with and without neurologic abnormalities.: J Acquir Immune Defic Syndr. 1994 Aug;7(8):777-88. Unique Identifier : AIDSLINE MED/94293159; Schmid P; Conrad A; Syndulko K; Singer EJ; Handley D; Li X; Tao G; Fahy-Chandon B; Tourtellotte WW; Neurology Service, DVA Medical Center West Los Angeles, Wadsworth; Division, California.; To quantify the number of human immunodeficiency virus type 1 (HIV-1) proviral copies per 1,000 CD4+ cells in cerebrospinal fluid (CSF) and blood in relationship to stage of infection and HIV-1 neurologic disease (HND), 87 HIV-1 seropositive men without CNS opportunistic infections, tumors, or neurosyphilis, 9 high-rit
Surface expression of the HIV-1 envelope proteins in env gene-transfected CD4-positive human T cell clones: characterization and killing by an antibody-dependent cellular cytotoxic mechanism.: J Acquir Immune Defic Syndr. 1994 Aug;7(8):789-98. Unique Identifier : AIDSLINE MED/94293160; Ahmad A; Yao XA; Tanner JE; Cohen E; Menezes J; Laboratory of Immunovirology, University of Montreal, Quebec,; Canada.; The env gene of the human immunodeficiency virus-type 1 (HIV-1) was transfected in CEM-nkr, a human lymphoid cell line of T lineage that is resistant to the activity of natural killer cells, and for the first time, transfected T cell clones were established that stably express gp160 intracellularly and gp120 on the sut
Clinical and immunological correlates of immune-complex-dissociated HIV-1 p24 antigen in HIV-1-infected children.: J Acquir Immune Defic Syndr. 1994 Aug;7(8):807-15. Unique Identifier : AIDSLINE MED/94293162; Duiculescu DC; Geffin RB; Scott GB; Scott WA; Victor Babes Hospital for Infectious Diseases, Bucharest,; Romania.; It has been reported that HIV-1 p24 antigen (p24 Ag) detection is improved after dissociation of immune complexes using acid treatment (ICD assay). In order to evaluate the clinical significance of p24 Ag detected by the standard assay and by the ICD assay in pediatric patients, we related these measurements to clinict
Oral candidiasis and immune status of HIV-infected patients.: J Oral Pathol Med. 1994 Mar;23(3):140-3. Unique Identifier : AIDSLINE MED/94293201; Nielsen H; Bentsen KD; Hojtved L; Willemoes EH; Scheutz F; Schiodt M; Stoltze K; Pindborg JJ; Department of Oral Pathology, School of Dentistry, University of; Copenhagen, Denmark.; A total of 84 HIV-infected homosexual men having either normal oral mucosa (NOM), erythematous candidiasis (EC) or pseudomembranous candidiasis (PsC) were included in the study. The patients were evaluated by median number of peripheral CD4+ cells, CD8+ cells and by lymphocyte function assessed by poke-weed mitogen tet
[AIDS-1993]: Rinsho Byori. 1994 May;42(5):446-52. Unique Identifier : AIDSLINE MED/94293477; Matsuda J; Department of Medicine, Teikyo University School of Medicine,; Tokyo.; Since the first case report of acquired immunodeficiency syndrome (AIDS) in patients with hemophilia from our department in 1994, we have treated more than 60 hemophiliacs infected with human immunodeficiency virus type-1 (HIV-1). During this decade, we have found and reported some useful laboratory-test markers for pt
HIV infection and leprosy: a four-year survey in Ethiopia.: Lancet. 1994 Jul 16;344(8916):165-6. Unique Identifier : AIDSLINE MED/94293686; Frommel D; Tekle-Haimanot R; Verdier M; Negesse Y; Bulto T; Denis F; Armauer Hansen Research Institute (AHRI), Addis Ababa, Ethiopia.; Between 1988 and 1992 three cross-sectional surveys for antibodies to HIV were done in 644 Ethiopian patients with histologically proven leprosy. Whereas the frequency of HIV-1 infection gradually increased from 3.2% to 6.5%, the clinical presentation, number of new patients, and frequency of relapse did not differ bet
Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): a possible mechanism for Tat's immunosuppressive activity.: Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6594-8. Unique Identifier : AIDSLINE MED/94294425; Gutheil WG; Subramanyam M; Flentke GR; Sanford DG; Munoz E; Huber BT; Bachovchin WW; Department of Biochemistry, Tufts University School of Medicine,; Boston, MA 02111.; The human immunodeficiency virus 1 (HIV-1) Tat protein suppresses antigen-induced, but not mitogen-induced, activation of human T cells when added to T-cell cultures [Viscidi, R. P., Mayur, K., Lederman, H. M. & Frankel, A. D. (1989) Science 246, 1606-1608]. This activity is potentially pertinent to the development
[Cutaneous hyperpigmentation in an HIV+ patient (letter)]: Rev Clin Esp. 1994 Apr;194(4):319-20. Unique Identifier : AIDSLINE MED/94294629; Caminal Montero L; Susano RC; Gonzalez Marroquin A; Taborcias Blanco D
The utility of large, simple trials in the evaluation of AIDS treatment strategies.: Stat Med. 1994 Mar 15-Apr 15;13(5-7):405-15. Unique Identifier : AIDSLINE MED/94294657; Ellenberg SS; Foulkes MA; Division of AIDS, National Institute of Allergy and Infectious; Diseases, Bethesda, Maryland 20892.
Circannual variation in lymphocyte subsets, revisited.: Transfusion. 1994 Jun;34(6):512-6. Unique Identifier : AIDSLINE MED/94295067; Paglieroni TG; Holland PV; Sacramento Medical Foundation Center for Blood Research,; California.; BACKGROUND: Circadian and circannual variations in lymphocyte subsets, especially CD8+ T-lymphocytes, have been reported. This study focuses on CD4+ T-lymphocyte seasonal variation over a 6-year 8-month period. STUDY DESIGN AND METHODS: Lymphocyte subsets were quantitated monthly for four healthy individuals from 1986
Cerebrospinal fluid human immunodeficiency virus type 1 (HIV-1) p24 antigen levels in HIV-1-related dementia.: Ann Neurol. 1994 Jul;36(1):32-9. Unique Identifier : AIDSLINE MED/94296064; Royal W 3rd; Selnes OA; Concha M; Nance-Sproson TE; McArthur JC; Department of Neurology, Johns Hopkins University School of; Medicine, Baltimore, MD.; Human immunodeficiency virus type 1 (HIV-1) p24 antigen, a putative marker of virus load, was assayed in 79 blood and 83 cerebrospinal fluid (CSF) samples from 90 HIV-1-seropositive individuals with or without dementia . Twenty-eight subjects had no evidence of neuropsychological im
[Validity of an ELISA test for CD4+ T lymphocyte count and validity of total lymphocyte count in the assessment of immunodeficiency status in HIV infection]: Ann Soc Belg Med Trop. 1994 Mar;74(1):61-8. Unique Identifier : AIDSLINE MED/94296163; Loua A; Kestens L; Vanham G; Boel L; Colebunders R; Gigase P; Departement de Biologie Clinique, CHU Ignace DEEN, Conakry,; Guinee.; A newly available commercial ELISA (TRAx CD4, T Cell Diagnostics USA) for enumerating CD4+ T lymphocytes has been evaluated with blood samples of 105 HIV seropositive and 6 seronegative subjects. Results from the flow cytometric analysis were used as reference. The sensitivity and specificity of the ELISA to identify
Close co-localization of CD4 and a serine esterase tryptase TL2 on the cell-surface of human monocytoid and CD4+ lymphoid cells.: Biochem Biophys Res Commun. 1994 Jun 30;201(3):1390-5. Unique Identifier : AIDSLINE MED/94296414; Inoue M; Hoshino T; Fukuma T; Niwa Y; Kido H; Department of Parasitology, Kurume University School of Medicine,; Fukuoka, Japan.; Tryptase TL2, a serine esterase in the membrane of human monocytoid and CD4+ lymphoid cells, specifically binds to the V3 domain of HIV-1 gp120. Here we report that monoclonal antibodies against CD4 that recognize the epitope interacting with gp120 specifically blocked the immunostaining of cell-surface tryptase TL2,
Immunohistochemical characterization of inflammatory cells and immunologic activation markers in muscle and nerve biopsy specimens from patients with systemic polyarteritis nodosa.: Arthritis Rheum. 1994 Jul;37(7):1055-61. Unique Identifier : AIDSLINE MED/94296454; Cid MC; Grau JM; Casademont J; Campo E; Coll-Vinent B; Lopez-Soto A; Ingelmo M; Urbano-Marquez A; Hospital Clinic i Provincial, University of Barcelona, Spain.; OBJECTIVE. To investigate the phenotype of infiltrating cells in classic lesions of polyarteritis nodosa (PAN). METHODS. Twenty-one muscle and 10 sural nerve biopsy samples from 24 patients with systemic PAN were studied using avidin-biotin-peroxidase and alkaline phosphatase-anti-alkaline phosphatase immunohistochemi
Characteristics of CD4+ T cells which transfer murine AIDS (MAIDS).: Cell Immunol. 1994 Jul;156(2):468-79. Unique Identifier : AIDSLINE MED/94298102; Donaldson LA; Cheng R; Savage SM; Sopori ML; Immunotoxicology Section, Lovelace Institutes, Albuquerque, New; Mexico 87108.; The murine acquired immunodeficiency syndrome (MAIDS) is caused in susceptible C57BL/6 (B6) mice by a defective murine leukemia virus (MuLV) and resembles human AIDS in several respects. The disease is characterized by hypergammaglobulinemia, polyclonal B cell activation, lymphadenopathy, and generalized immunosuppres
Interleukin-12 (IL-12) augments cytolytic activity of natural killer cells toward Mycobacterium tuberculosis-infected human monocytes.: Cell Immunol. 1994 Jul;156(2):529-36. Unique Identifier : AIDSLINE MED/94298107; Denis M; Pulmonary Research Unit, Faculty of Medicine, University of; Sherbrooke, Quebec, Canada.; We tested the impact of interleukin-12 (IL-12) and of cytotoxic leukocytes (particularly natural killer (NK) cells) from normal and HIV-1-infected subjects on lysis of human monocytes infected with Mycobacterium tuberculosis. Nylon wool nonadherent cells stimulated with interleukin-2 (
Prophylaxis of opportunistic infections in persons with HIV infection.: Cleve Clin J Med. 1994 May-Jun;61(3):187-94. Unique Identifier : AIDSLINE MED/94298220; Stearn BF; Polis MA; Intramural AIDS Program, National Institutes of Health, Bethesda,; Md 20892.; BACKGROUND: Morbidity and mortality associated with human immunodeficiency virus infection and the acquired immunodeficiency syndrome is most often related to associated opportunistic infections. OBJECTIVE: To review the prophylaxis of common opportunistic infections in patients with human immunodeficiency virus. SUMM
Deletion of T lymphocytes in human CD4 transgenic mice induced by HIV-gp120 and gp120-specific antibodies from AIDS patients.: Eur J Immunol. 1994 Jul;24(7):1553-7. Unique Identifier : AIDSLINE MED/94298855; Wang ZQ; Orlikowsky T; Dudhane A; Mittler R; Blum M; Lacy E; Riethmuller G; Hoffmann MK; Department of Microbiology and Immunology, New York Medical; College, Valhalla 10595.; CD4, a T cell receptor for major histocompatibility complex class II antigen, is a key regulator of immunological reactivities. When engaged together with the T cell antigen receptor, CD4 enhances immune reactions, whereas when ligated independently of the antigen receptor CD4 inhibits the activation of T cells or ini
Zidovudine for mother, fetus, and child: hope or poison? [editorial] [see comments]: Lancet. 1994 Jul 23;344(8917):207-9. Unique Identifier : AIDSLINE MED/94301074
Impact of Thailand's HIV-control programme as indicated by the decline of sexually transmitted diseases.: Lancet. 1994 Jul 23;344(8917):243-5. Unique Identifier : AIDSLINE MED/94301089; Hanenberg RS; Rojanapithayakorn W; Kunasol P; Sokal DC; Family Health International, Research Triangle Park, North; Carolina.; The Thai government began an HIV-control programme in 1989. The programme had the following parts: the government bought and distributed sufficient condoms to protect much of the commercial sex in the country; sanctions were brought against commercial sex establishments where condoms were not used consistently; and a
Condom promotion, sexually transmitted diseases treatment, and declining incidence of HIV-1 infection in female Zairian sex workers.: Lancet. 1994 Jul 23;344(8917):246-8. Unique Identifier : AIDSLINE MED/94301090; Laga M; Alary M; Nzila N; Manoka AT; Tuliza M; Behets F; Goeman J; St Louis M; Piot P; Department of Infection and Immunity, WHO Collaborating Centre on; AIDS, Institute of Tropical Medicine, Antwerp, Belgium.; The control of sexually transmitted diseases, including HIV-1, among sex workers and their clients in urban areas in developing countries, is considered a valuable and cost-effective intervention to contain the spread of HIV-1. The effect of a programme of STD treatment combined with condom promotion on HIV-1 incidenc
NIH and Pasteur: AIDS-test royalties [news]: Lancet. 1994 Jul 23;344(8917):253. Unique Identifier : AIDSLINE MED/94301092; Greenberg DS
US AIDS czar quits [news]: Lancet. 1994 Jul 23;344(8917):254. Unique Identifier : AIDSLINE MED/94301093; McCarthy M
French ministers to be charged for blood scandal [news]: Lancet. 1994 Jul 23;344(8917):256. Unique Identifier : AIDSLINE MED/94301094; Nau JY
New retroviruses in human and simian T-lymphotropic viruses [letter]: Lancet. 1994 Jul 23;344(8917):265-6. Unique Identifier : AIDSLINE MED/94301105; Liu HF; Vandamme AM; Van Brussel M; Desmyter J; Goubau P
Immunological effects of unemployment [letter]: Lancet. 1994 Jul 23;344(8917):269-70. Unique Identifier : AIDSLINE MED/94301113; Marriott D; Kirkwood BJ; Stough C
No HIV-1 transmission through lesbian sex [letter] [see comments]: Lancet. 1994 Jul 23;344(8917):270. Unique Identifier : AIDSLINE MED/94301114; Raiteri R; Fora R; Sinicco A
New HIV-1 subtype in Switzerland [letter]: Lancet. 1994 Jul 23;344(8917):270-1. Unique Identifier : AIDSLINE MED/94301115; Joller-Jemelka HJ; Sandoz PF; Glauser A; Joller PW
Septata intestinalis: a new microsporidian in Africa [letter]: Lancet. 1994 Jul 23;344(8917):271-2. Unique Identifier : AIDSLINE MED/94301116; Kelly P; McPhail G; Ngwenya B; Luo N; Karew AH; Pankhurst C; Drobniewski F; Farthing M
The pathogenesis of HIV infection.: Rays. 1994 Jan-Mar;19(1):15-28. Unique Identifier : AIDSLINE MED/94302307; Ortona L; Antinori A; Istituto di Clinica delle Malattie Infettive, Universita; Cattolica del S. Cuore, Policlinico A. Gemelli, Roma.
Autoantibodies against ganglioside GM3 represent a portion of anti-lymphocyte antibodies in AIDS patients.: Scand J Immunol. 1994 Jul;40(1):77-82. Unique Identifier : AIDSLINE MED/94302480; Griggi T; Bauer R; Garofalo T; Kukel S; Lenti L; Massetti AP; Muller C; Sorice M; Pontieri GM; Department of Dermatology, University of Bonn, Germany.; In this study we analysed the relationship between anti-lymphocytic ganglioside antibodies and anti-lymphocyte antibodies in AIDS patients. Anti-lymphocytic ganglioside antibodies were detected by thin layer chromatography (TLC) immunostaining; three colour flow cytometry was used to analyse circulating antibodies aga
Natural killer cell stimulatory factor (NKSF)/IL-12 and cytolytic activities of PBL/NK cells from human immunodeficiency virus type-1 infected patients.: Scand J Immunol. 1994 Jul;40(1):83-6. Unique Identifier : AIDSLINE MED/94302481; Sirianni MC; Ansotegui IJ; Aiuti F; Wigzell H; Department of Clinical Immunology and Allergy, University of Rome; La Sapienza, Italy.; The aim of this study was to assess the effect of natural killer stimulatory factor (NKSF)/IL-12) on the cytolytic potential of natural killer (NK) cells from normal donors or HIV-1 infected individuals, at different stages of disease. The results obtained confirm the powerful ability of IL-12 to enhance PBLs cytotox
Gene therapy for infectious diseases: the AIDS model.: Trends Genet. 1994 Apr;10(4):139-44. Unique Identifier : AIDSLINE MED/94302677; Gilboa E; Smith C; Department of Surgery, Duke University Medical Center, Durham, NC; 27710.; Genetic manipulation of somatic cells may be of therapeutic value in a variety of infectious diseases, particularly in human immunodeficiency virus (HIV) infection. Stable insertion of custom-designed resistance genes into cells susceptible to HIV could reduce the viral burden in infected individuals and potentially
Xenotransplantation of hematopoietic cells resistant to HIV as a potential treatment for patients with AIDS.: Transplant Proc. 1994 Jun;26(3):1302-3. Unique Identifier : AIDSLINE MED/94302798; Ricordi C; Tzakis AG; Rybka WB; Fontes P; Ball ED; Trucco M; Kocova M; Triulzi D; McMichael J; Doyle H; et al; University of Pittsburgh Medical Center, Pennsylvania.
Correlation between changes in cellular immunity and rejection in rat small bowel transplantation.: Transplant Proc. 1994 Jun;26(3):1557. Unique Identifier : AIDSLINE MED/94302942; Wang P; Zhu L; Liu T; He X; Zhu W; Tianjin Medical College Hospital, PR China.
NF-kappa B-dependent and -independent pathways of HIV activation in a chronically infected T cell line.: Virology. 1994 Aug 1;202(2):684-94. Unique Identifier : AIDSLINE MED/94303183; Antoni BA; Rabson AB; Kinter A; Bodkin M; Poli G; New Jersey Center for Advanced Biotechnology and Medicine (CABM),; Department of Viral Pathogenesis, Piscataway.; J delta K cells were isolated as a chronically infected survivor cell line, following infection of Jurkat CD4+ T cells with dl-NF, a mutated strain of human immunodeficiency virus type 1 (HIV-1) containing a deletion of the long terminal repeat (LTR) NF-kappa B sites. J delta K cells exhibited very low levels of const
Mechanism of the inhibitory effect of curdlan sulfate on HIV-1 infection in vitro.: Virology. 1994 Aug 1;202(2):735-45. Unique Identifier : AIDSLINE MED/94303188; Jagodzinski PP; Wiaderkiewicz R; Kurzawski G; Kloczewiak M; Nakashima H; Hyjek E; Yamamoto N; Uryu T; Kaneko Y; Posner MR; et al; Department of Microbiology, Thomas Jefferson University,; Philadelphia, Pennsylvania 19107.; To study the mechanism by which sulfated polysaccharides with 1,3-beta-D-glucan as a main chain exert anti-HIV-1 activity, we analyzed the effects of curdlan sulfate (CRDS) on HIV-1 infection of SupT-1 cells and peripheral blood mononuclear cells. CRDS had no effect on virions inhibited weakly HIV-1 attachment to cell
Highly potent and selective inhibition of human immunodeficiency virus by the bicyclam derivative JM3100.: Antimicrob Agents Chemother. 1994 Apr;38(4):668-74. Unique Identifier : AIDSLINE MED/94304107; De Clercq E; Yamamoto N; Pauwels R; Balzarini J; Witvrouw M; De Vreese K; Debyser Z; Rosenwirth B; Peichl P; Datema R; et al; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.; Bicyclams, in which the cyclam (1,4,8,11-tetraazacyclotetradecane) moieties are tethered via an aliphatic bridge (i.e., propylene, as in JM2763) are potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) (E. De Clercq, N. Yamamoto, R. Pauwels, M. Baba, D. Schols, H. Nakashima
CD4+ T-lymphocyte measures in the treatment of individuals infected with human immunodeficiency virus type 1. A review for clinical practitioners.: Arch Intern Med. 1994 Jul 25;154(14):1561-73. Unique Identifier : AIDSLINE MED/94304296; Turner BJ; Hecht FM; Ismail RB; Division of General Internal Medicine, Jefferson Medical College,; Philadelphia, Pa.; The CD4+ lymphocyte is a major target of the human immunodeficiency virus type 1 (HIV-1). CD4+ T-lymphocyte measures have been used to predict the risk of HIV-1-related complications in diverse populations, to guide management decisions, and to define cases of the acquired immunodeficiency syndrome (AIDS). To examine
[The stakes in preventing opportunistic MAI infections in AIDS. From an interview with Dr. Patrick Philibert]: Allerg Immunol (Paris). 1994 Apr;26(4):145-8. Unique Identifier : AIDSLINE MED/94304497; Philibert P; Development of HIV infection is littered with many pathological episodes of which the physical and psychological repercussions on the patient are full of consequences. In this context, full co-operation between the hospital services and general practitioners is fundamental, from the moment of the announcement of serop
Diagnostic value for culture of cerebrospinal fluid from HIV-1-infected individuals for opportunistic viruses: a prospective study.: AIDS. 1994 Mar;8(3):307-12. Unique Identifier : AIDSLINE MED/94304550; Dix RD; McCarthy M; Berger JR; Department of Ophthalmology, University of Miami School of; Medicine, Florida.; OBJECTIVE: To investigate the diagnostic value of cerebrospinal fluid (CSF) culture for opportunistic viruses from HIV-1-infected individuals. METHODS: A 4-year prospective study was conducted using a participant population consisting of 186 HIV-1-infected individuals without neurologic disease, 73 HIV-1-infected indi
Zidovudine twice daily in asymptomatic subjects with HIV infection and a high risk of progression to AIDS: a randomized, double-blind placebo-controlled study. The European-Australian Collaborative Group (Study 017) [published erratum appears in AIDS 1994 Jun;8(6):following 859] [see comments]: AIDS. 1994 Mar;8(3):313-21. Unique Identifier : AIDSLINE MED/94304551; Mulder JW; Cooper DA; Mathiesen L; Sandstrom E; Clumeck N; Gatell JM; French M; Donovan B; Gray F; Yeo JM; et al; Slotervaatziekenhuis, Department of Internal Medicine, Amsterdam,; The Netherlands.; OBJECTIVE: To evaluate the efficacy of zidovudine given twice daily in subjects with asymptomatic HIV-1 infection and a high risk of progression to AIDS. DESIGN: Randomized, double-blind placebo-controlled trial. SETTING: Multicentre study in five European countries and Australia
Quasispecies dynamics and the emergence of drug resistance during zidovudine therapy of HIV infection.: AIDS. 1994 Mar;8(3):323-32. Unique Identifier : AIDSLINE MED/94304552; Frost SD; McLean AR; Department of Zoology, University of Oxford, U.K.; OBJECTIVE: To investigate the roles of mutation, competition and population dynamics in the emergence of drug resistant mutants during zidovudine therapy. DESIGN: A mathematical model of the population dynamics of the viral quasispecies during zidovudine therapy was investigated. METHODS: The model was used to simulat
Continued drug use and other cofactors for progression to AIDS among injecting drug users.: AIDS. 1994 Mar;8(3):339-43. Unique Identifier : AIDSLINE MED/94304554; Ronald PJ; Robertson JR; Elton RA; Edinburgh Drug Addiction Study, University of Edinburgh,; Scotland, UK.; OBJECTIVE: To evaluate the effects of continued drug use and other cofactors on progression to AIDS among HIV-infected injecting drug users. DESIGN: A prospective study. SETTING: The Muirhouse Medical Group in Edinburgh, Scotland, UK. SUBJECTS: A total of 156 HIV-infected injecting drug users. MAIN OUTCOME MEASURES: P
CD4+ T-lymphocytopenia and severe infections in an HIV-negative Ethiopian man [letter]: AIDS. 1994 Mar;8(3):390-1. Unique Identifier : AIDSLINE MED/94304565; Montella F; Viola P; Recchia O; Di Sora F; Rezza G
Sexually transmitted diseases in the AIDS era [published erratum appears in Int J STD AIDS 1994 Sep-Oct;5(5):382]: Int J STD AIDS. 1994 Mar-Apr;5(2):149-51. Unique Identifier : AIDSLINE MED/94305015; Waugh MA; GUM Department, Leeds General Infirmary, UK.
HIV nursing: caring for the future. Summary proceedings, HIV nursing summit.: J Assoc Nurses AIDS Care. 1994 Mar-Apr;5(2):29-30. Unique Identifier : AIDSLINE MED/94305113; Stanley S
HIV-1 gp41 enhances major histocompatibility complex class I and ICAM-1 expression on H9 and U937 cells.: Int Arch Allergy Immunol. 1994 Jul;104(3):227-31. Unique Identifier : AIDSLINE MED/94305372; Chen YH; Bock G; Vornhagen R; Steindl F; Katinger H; Dierich MP; Ludwig Boltzmann Institute for AIDS Research, Innsbruck, Austria.; Based on our findings that HIV-1 (human immunodeficiency virus type 1) soluble gp41 (sgp41; amino acids 539-684) bound to human T, B, and monocyte cells and enhanced major histocompatibility complex (MHC) class I and II antigen expression on Raji cells, we examined the effect of HIV-1 sgp41 on the surface expression o
Study of B and T cell phenotypes in blood from patients with common variable immunodeficiency (CVID).: Immunodeficiency. 1994;5(2):159-69. Unique Identifier : AIDSLINE MED/94305532; Farrant J; Spickett G; Matamoros N; Copas D; Hernandez M; North M; Chapel H; Webster AD; Immunodeficiency Diseases Research Group, Clinical Research; Centre, Harrow, UK.; B and T cell phenotypes in peripheral blood from 71 CVID patients have been measured in a study using directly conjugated monoclonal antibodies and two colour flow cytometry. Data was compared between different patient groups (based on whether their B cells could secrete IgM or IgG in vitro) and normal donors. There w
Serum and cerebrospinal fluid levels of soluble intercellular adhesion molecule 1 (sICAM-1) in patients with HIV-1 associated neurological diseases.: J Neuroimmunol. 1994 Jul;52(2):117-26. Unique Identifier : AIDSLINE MED/94308290; Heidenreich F; Arendt G; Jander S; Jablonowski H; Stoll G; Department of Neurology, Heinrich-Heine Universitat,; Dusseldorf, Germany.; We measured levels of soluble intercellular adhesion molecule 1 (sICAM-1) in paired serum and CSF samples of 110 HIV-1-positive patients with and without neurological symptoms and 40 HIV-negative non-immune neurological controls, and in sera of 26 asymptomatic HIV-1-positive patients. Serum sICAM-1 levels in asymptoma
Environmental risk factors for acquisition of Mycobacterium avium complex in persons with human immunodeficiency virus infection.: J Infect Dis. 1994 Aug;170(2):362-7. Unique Identifier : AIDSLINE MED/94308603; Horsburgh CR Jr; Chin DP; Yajko DM; Hopewell PC; Nassos PS; Elkin EP; Hadley WK; Stone EN; Simon EM; Gonzalez P; et al; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, Georgia 30333.; A case-control study was done to determine risk factors for Mycobacterium avium complex (MAC) disease in persons infected with human immunodeficiency virus (HIV) with
Improvement in CD4 lymphocyte count in HIV-Reiter's syndrome after treatment with sulfasalazine.: J Rheumatol. 1994 Apr;21(4):662-4. Unique Identifier : AIDSLINE MED/94309030; Disla E; Rhim HR; Reddy A; Taranta A; Department of Medicine, Cabrini Medical Center, New York, NY; 10003.; OBJECTIVE. To describe an observed improvement in CD4 lymphocytes in patients with Reiter s syndrome (RS) and human immunodeficiency virus (HIV) infection, after treatment with sulfasalazine (SFSZ). METHODS . Care series. We analyzed CD4 lymphocyte counts in 4 consecutive patients with RS and HIV disease before and af
In vivo induction of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes and delayed-type hypersensitivity by a 23-amino acid peptide from the highly conserved region in major core protein p24.: Vaccine. 1994 May;12(6):485-91. Unique Identifier : AIDSLINE MED/94310824; Nishino Y; Kameoka M; Okada Y; Zhong Q; Kimura T; Azuma I; Ikuta K; Institute of Immunological Science, Hokkaido University, Sapporo,; Japan.; Cell-mediated immune responses are a major immune defence mechanism against the spread of human immunodeficiency virus type 1 (HIV-1) which may lead to acquired immune deficiency syndrome (AIDS). Therefore, the best candidate for a peptide vaccine preventive from the onset of the disease might be a chain section conta
Managing early human immunodeficiency virus infection. Agency for Health Care Policy and Research.: Am J Hosp Pharm. 1994 Apr 15;51(8):1003-20. Unique Identifier : AIDSLINE MED/94311328
[Otoneurologic examination of patients with AIDS]: An Otorrinolaringol Ibero Am. 1994;21(3):307-20. Unique Identifier : AIDSLINE MED/94311494; Broto J; Fuster J; Zamora L; Traserra J; Gatell JM; Servicio de O.R.L. Hospital Clinic, Barcelona.; The influence of the HIV virus on the central nervous system tracts has been definitively shown. Over the past year we have affected otoneurologic tests based on elicited auditive potentials and tests of oculomotility on a total of 30 patients affected by stages II and III of the disease. The results show that around
Granular lymphocyte proliferative disorders: a multicenter study of 20 cases.: Ann Hematol. 1994 Jun;68(6):285-92. Unique Identifier : AIDSLINE MED/94312465; Woessner S; Feliu E; Villamor N; Zarco MA; Domingo A; Milla F; Florensa L; Rozman M; Abella E; Soler J; et al; Catalonian Group of Hematological Cytology, Hospital La Alianca,; Barcelona, Spain.; A series of 20 patients with granular lymphocyte proliferative disorders (GLPD) is reported. The criterion of inclusion was presence of persistent (> or = 6 months) granular lymphocytosis in the absence of any causative illness. Diagnoses made upon analytical control in half the patients of splenomegaly (25%) and hepa
Cytochalasin D modulates CD4 crosslinking sensitive mitogenic signal in T lymphocytes.: Cell Immunol. 1994 Aug;157(1):81-91. Unique Identifier : AIDSLINE MED/94313697; Aszalos A; Pine PS; Weaver JL; Rao PE; Center for Drug Evaluations and Research, FDA, Washington, DC; 20204.; It has previously been shown that crosslinking of the CD4 molecule, either with anti-Leu3a mAb or with gp120 (the HIV coat protein) plus anti-gp120 mAb, suppresses activation induced by wt31, a TcR/CD3-specific mAb. This suppression was associated with hindrance of the necessary association of the p56lck kinase bearin
Sample size estimation using repeated measurements on biomarkers as outcomes.: Control Clin Trials. 1994 Jun;15(3):165-72. Unique Identifier : AIDSLINE MED/94313870; Kirby AJ; Galai N; Munoz A; Department of Epidemiology, Johns Hopkins School of Hygiene and; Public Health, Baltimore, Maryland.; The objectives of this paper are to (1) examine methods of using longitudinal data in designing comparative trials and calculating sample sizes or power and (2) show the effect of autocorrelation of repeated measures on the assessment of sample sizes. A statistical model with a simple regression structure for the mean
Measurement of CD4+ percentage [letter; comment]: JAMA. 1994 Aug 10;272(6):434. Unique Identifier : AIDSLINE MED/94315716; Olson PE; Wallace MR
The duration of zidovudine benefit in persons with asymptomatic HIV infection. Prolonged evaluation of protocol 019 of the AIDS Clinical Trials Group [see comments]: JAMA. 1994 Aug 10;272(6):437-42. Unique Identifier : AIDSLINE MED/94315721; Volberding PA; Lagakos SW; Grimes JM; Stein DS; Balfour HH Jr; Reichman RC; Bartlett JA; Hirsch MS; Phair JP; Mitsuyasu RT; et al; University of California-San Francisco.; OBJECTIVE--To determine the durability of zidovudine-induced delay in clinical progression of asymptomatic human immunodeficiency virus (HIV) disease and to assess the relationship between this effect and the entry CD4+ cell count. DESIGN AND INTERVENTIONS--Extended follow-up data from subjects participating in protoc
Neutralizing antibodies to HIV-1 in seronegative volunteers immunized with recombinant gp120 from the MN strain of HIV-1. NIAID AIDS Vaccine Clinical Trials Network [see comments]: JAMA. 1994 Aug 10;272(6):475-80. Unique Identifier : AIDSLINE MED/94315727; Belshe RB; Graham BS; Keefer MC; Gorse GJ; Wright P; Dolin R; Matthews T; Weinhold K; Bolognesi DP; Sposto R; et al; Department of Medicine, St Louis University School of Medicine,; MO 63104.; OBJECTIVE--To evaluate the safety and immunogenicity of the MN strain of recombinant gp120 (MN rgp120) as a vaccine prototype to prevent human immunodeficiency virus (HIV). DESIGN--Double-blind, randomized, placebo-controlled study with subjects vaccinated at 0, 4, 24, and 48 weeks and followed up through 64 weeks. SE
[Animal toxicology studies necessary for clinical research and the registry of drugs for human use: conclusions of the International Conference of Harmonization (and II)]: Med Clin (Barc). 1994 May 28;102(20):791-6. Unique Identifier : AIDSLINE MED/94315976; Tristan C; Galende I; Rubio Terres C; Duque I; Subdireccion General de Evaluacion de Medicamentos, Ministerio; de Sanidad y Consumo, Madrid.
CD8+ T lymphocytes of African green monkeys secrete an immunodeficiency virus-suppressing lymphokine.: Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7207-11. Unique Identifier : AIDSLINE MED/94316666; Ennen J; Findeklee H; Dittmar MT; Norley S; Ernst M; Kurth R; Paul-Ehrlich Institute, Langen, Germany.; Following natural and experimental infection by simian immunodeficiency virus SIVagm of African green monkeys (AGMs), the natural host, there is no evidence for the development of an immunodeficiency. Within the framework of our studies on human immunodeficiency virus (HIV)/SIV pathogenesis, we investigated the influe
Human immunodeficiency virus type 1 and type 2 seroprevalence in cornea donors [published erratum appears in Ger J Ophthalmol 1994 Aug;3(4-5):260]: Ger J Ophthalmol. 1994 May;3(3):182-5. Unique Identifier : AIDSLINE MED/94312983; Geier SA; Klauss V; Gurtler L; University Eye Hospital Munich, Germany.; Routine screening of cornea donors for human immunodeficiency virus type 1 (HIV-1) has been established and has reduced the risk of HIV-1 transmission to a minimum. Screening for HIV-2 is less common. We evaluated 100 cornea donors for HIV-2 and 166 cornea donors for HIV-1 according to our routine screening procedure.
Neurosyphilis and HIV infection [see comments]: Int J STD AIDS. 1994 Mar-Apr;5(2):146-8. Unique Identifier : AIDSLINE MED/94305014; Wardropper AG; Snow M; Genito-Urinary Medicine Clinic, Newcastle General Hospital,; Newcastle-upon-Tyne, UK.
Multiepitope polypeptide of the HIV-1 envelope induces neutralizing monoclonal antibodies against V3 loop.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):235-43. Unique Identifier : AIDSLINE MED/94289061; Duarte CA; Montero M; Seralena A; Valdes R; Jimenez V; Benitez J; Narciandi E; Madrazo J; Padron G; Sanchez G; et al; Center for Genetic Engineering and Biotechnology, Havana, Cuba.; A gene encoding a multiepitope polypeptide (MEP) has been synthesized. It contains the information for (1) an 11-amino acid (aa) epitope from the C1 region of gp120 of HIV-1 and (2) 3 epitopes of 15 amino acids each, from the central part of the V3 loop of isolates MN, SC, and WMJII. These four segments are linked by
Cross-reactivity between autoimmune anti-U1 snRNP antibodies and neutralizing epitopes of HIV-1 gp120/41.: AIDS Res Hum Retroviruses. 1994 Mar;10(3):253-62. Unique Identifier : AIDSLINE MED/94289063; Douvas A; Takehana Y; Department of Medicine, University of Southern California Health; Sciences Center, Los Angeles 90033.; We report extensive amino acid sequence homology between HIV-1 gp120/41, and > 33% of a U1 RNA-associated splicing protein, 70K. The latter is a target of autoimmune anti-RNP antibodies in mixed connective tissue disease (MCTD). The homologies, involving dominant epitopes of 70K and neutralizing epitopes of gp120/41,
Reducing AIDS and other STDs among inner-city Hispanics: the use of qualitative research in the development of video-based patient education.: AIDS Educ Prev. 1994 Apr;6(2):140-53. Unique Identifier : AIDSLINE MED/94289148; O'Donnell L; San Doval A; Vornfett R; DeJong W; Education Development Center, Inc., Newton, MA 02160.; We report on the use of qualitative research in the design of video-based interventions aimed at reducing AIDS and other sexually transmitted diseases (STDs) among inner-city Hispanics. Focus groups, personal interviews, and clinic observations were conducted in the South Bronx and Queens, New York, to inform the deve
An experimental evaluation of an AIDS educational intervention for WIC mothers.: AIDS Educ Prev. 1994 Apr;6(2):154-62. Unique Identifier : AIDSLINE MED/94289149; Ashworth CS; DuRant RH; Gaillard G; Rountree J; Department of Pediatrics, University of Alabama at Birmingham.; The purpose of this study is to determine which of two educational approaches have the greater effect on the AIDS/human immunodeficiency virus (HIV) knowledge and attitudes of women participating in the Women, Infants, and Children (WIC) Program. A modified version of the Centers for Disease Control s (CDC) 1989 Healt
Interleukin-2-dependent T-cell lines established from paroxysmal nocturnal hemoglobinuria patients.: Blood. 1994 Jul 1;84(1):309-14. Unique Identifier : AIDSLINE MED/94289717; Nakakuma H; Nagakura S; Horikawa K; Hidaka M; Kawaguchi T; Iwamoto N; Sanada I; Kagimoto T; Takatsuki K; Second Department of Internal Medicine, Kumamoto University; School of Medicine, Japan.; Peripheral blood T lymphocytes obtained from two patients with paroxysmal nocturnal hemoglobinuria (PNH) were immortalized with human T-lymphotropic virus type 1 (HTLV-1). These cells showed interleukin-2 ( IL-2 )-dependent cell growth in culture. Cell surface analysis s
Is there IgA of gut mucosal origin in the serum of HIV1 infected patients?: Gut. 1994 Jun;35(6):803-8. Unique Identifier : AIDSLINE MED/94292010; Quesnel A; Moja P; Lucht F; Touraine JL; Pozzetto B; Genin C; Laboratory of Research in Immunology, University of; Saint-Etienne, INSERM, Lyon, France.; This study was performed in 77 HIV1 seropositive adult patients to characterise the IgA hyperglobulinaemia seen in the serum during the course of HIV infection. It was shown that both IgA1 and IgA2 subclass concentrations were simultaneously increased but the IgA1 increase was predominant. Secretory IgA (SIgA) concent
High rate of nonspecific anti-hepatitis C reactivity amongst homosexual men in comparison with that found in other sexually active groups and blood donors. Viral Hepatitis and AIDS Study Group.: J Intern Med. 1994 Jul;236(1):73-7. Unique Identifier : AIDSLINE MED/94292895; Andreu J; Abad MA; Sanchez-Quijano A; Torronteras R; Luque F; Garcia de las Heras J; Soto B; Pineda JA; Leal M; Lissen E; Department of Internal Medicine, Virgen del Rocio University; Hospital, Seville, Spain.; OBJECTIVES. To investigate the concordance of anti-hepatitis C virus (anti-HCV) reactivity by a second-generation enzyme immunoassay (EIA-2) and by a four-antigen recombinant immunoblot assay (4-RIBA) in homosexual men, in comparison with that found in other sexually active groups and blood donors. DESIGN. Prospective
DNA found in human immunodeficiency virus type 1 particles may not be required for infectivity.: J Gen Virol. 1994 Jul;75 ( Pt 7):1605-13. Unique Identifier : AIDSLINE MED/94292911; Arts EJ; Mak J; Kleiman L; Wainberg MA; Lady Davis Institute, Jewish General Hospital, Montreal,; Quebec, Canada.; We have studied the presence and significance of retroviral genome-derived DNA in the core of human immunodeficiency virus (HIV) particles produced from transfections of HXB2 expression vectors in COS-7 cells and from HIV type 1 IIIB chronically infected H9 cells. Viruses purified by sucrose cushion centrifugation and
HIV-1 syncytium-inducing phenotype, virus burden, codon 215 reverse transcriptase mutation and CD4 cell decline in zidovudine-treated patients [see comments]: J Acquir Immune Defic Syndr. 1994 Aug;7(8):832-8. Unique Identifier : AIDSLINE MED/94293165; Kozal MJ; Shafer RW; Winters MA; Katzenstein DA; Aguiniga E; Halpern J; Merigan TC; Center for AIDS Research, Stanford University Medical Center,; California 94305.; The variable rate of disease progression in HIV-1-infected patients treated with zidovudine may be related to certain viral characteristics, such as, antiviral drug resistance, virus burden, and viral syncytium-inducing (SI) capacity. Thirty-two HIV-1-infected patients treated with zidovudine (mean of 34 months) were
Comparison of a lesion-inducing isolate and a non-lesional isolate of Candida albicans in an immunosuppressed rat model of oral candidiasis.: J Oral Pathol Med. 1994 Mar;23(3):133-9. Unique Identifier : AIDSLINE MED/94293200; Allen CM; Saffer A; Meister RK; Beck FM; Bradway S; Section of Oral and Maxillofacial Surgery and Pathology, Ohio; State University, Columbus 43210.; Two distinct strain-related patterns of organism-host interaction on dorsal tongue of immunocompetent rats have been identified for Candida albicans: some isolates induce mucosal lesions, while other isolates penetrate the keratin layer but do not produce a lesion. This study examined the behavior of each of the two t
Intraepithelial lymphocyte subpopulations and dendritic accessory cells in normal and hypertrophic adenoids.: Laryngoscope. 1994 Jul;104(7):869-73. Unique Identifier : AIDSLINE MED/94293745; Bani D; Gallo O; Fini-Storchi O; Department of Human Anatomy and Histology, University of; Florence, Italy.; The adenoids have been studied by immunocytochemistry and electron microscopy in children with and without adenoidal enlargement. Compared with normal adenoids, the enlarged ones showed a marked increase in the number of intraepithelial gamma-delta TCR+ lymphocytes and a slight increase in the number of intraepithelia
Human immunodeficiency virus 1 (HIV-1)-specific reverse transcriptase (RT) inhibitors may suppress the replication of specific drug-resistant (E138K)RT HIV-1 mutants or select for highly resistant (Y181C-->C181I)RT HIV-1 mutants.: Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6599-603. Unique Identifier : AIDSLINE MED/94294426; Balzarini J; Karlsson A; Sardana VV; Emini EA; Camarasa MJ; De Clercq E; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.; Mutant HIV-1 that expresses a Glu138-->Lys substitution in its RT [(E138K)RT] is resistant to the HIV-1-specific RT inhibitor 2 ,5 -bis-O-(tert-butyldimethylsilyl)-3 -spiro-5-(4-amino-1,2- oxathiole-2,2-dioxide)pyrimidine (TSAO). However, cell cultures infected with this mutant were completely protected against virus-
Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA.: Proc Natl Acad Sci U S A. 1994 Jul 5;91(14):6609-13. Unique Identifier : AIDSLINE MED/94294428; Feig DI; Sowers LC; Loeb LA; Department of Biochemistry, University of Washington, Seattle; 98195.; An understanding of the contribution of reactive oxygen species to mutagenesis has been hampered by the vast number of different chemical modifications they cause in DNA. Even though many of these DNA alterations have been catalogued, the identification of specific lesions that cause mutations has depended on testing
The boundaries of the self and the unhealthy other: reflections on health, culture and AIDS.: Soc Sci Med. 1994 May;38(10):1347-65. Unique Identifier : AIDSLINE MED/94294838; Crawford R; University of Washington at Tacoma 98402.; Most accounts of the cultural stigmas associated with AIDS have not adequately considered the meanings through which the stigmatizing self imagines his/her difference from the stigmatized other. This paper argues that health is a key concept in the fashioning of identity for the modern and contemporary middle class
Rhodococcus equi pneumonia and pulmonary malakoplakia in acquired immunodeficiency syndrome. Pathologic features.: Arch Pathol Lab Med. 1994 Jul;118(7):744-8. Unique Identifier : AIDSLINE MED/94296228; Kwon KY; Colby TV; Department of Pathology, Keimyung University School of Medicine,; Taegu, Korea.; Pulmonary infection with Rhodococcus equi is rare, and most cases are seen in immunocompromised patients, particularly those with acquired immunodeficiency syndrome. We describe the pathologic features in four cases of culture-positive R equi pneumonia occurring in patients infected with human immunodeficiency virus.
Sensitivity of (138 Glu-->Lys) mutated human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) to HIV-1-specific RT inhibitors.: Biochem Biophys Res Commun. 1994 Jun 30;201(3):1305-12. Unique Identifier : AIDSLINE MED/94296403; Balzarini J; Kleim JP; Riess G; Camarasa MJ; De Clercq E; Karlsson A; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.; Human immunodeficiency virus type 1 (HIV-1) recombinant reverse transcriptase (RT) containing lysine (Lys) instead of glutamic acid (Glu) at position 138 proved fully resistant to the inhibitory effect of TSAO derivatives, but retained marked sensitivity to all other HIV-1-specific inhibitors investigated. In contrast
AIDS and HIV infection worldwide.: Commun Dis Rep CDR Wkly. 1994 May 20;4(20):95-6. Unique Identifier : AIDSLINE MED/94297665
[Oligodeoxyribonucleotides complementary to sections of the mollicute ribosomal operon as transcription inhibitors in vitro]: Mikrobiol Z. 1993 Nov-Dec;55(6):29-35. Unique Identifier : AIDSLINE MED/94297755; Babichev VV; Skripal' IG; Bezuglyi SV; Panchenko LP; Shalamai AS; Makitruk BL; Goncharenko VS; Shimko NN; Antisense oligodeoxyribonucleotides have been studied for their effect on the transcription in vitro in mollicutes. A synthetic fragment of DNA [symbol: see text] complementary to that part of DNA which codes the 1510-1521 area of the 3 -terminal sequence 16S-pRNA of all mollicutes was used in the study as well as its
An HIV p24 heptapeptide down-regulates antigen-specific responses in vitro interfering at the level of the T3-Ti complex.: Cell Immunol. 1994 Jul;156(2):286-95. Unique Identifier : AIDSLINE MED/94298086; Luzzati AL; Giacomini E; Giordani L; Viora M; Chersi A; Camponeschi B; Pugliese O; Department of Immunology, Istituto Superiore di Sanita, Rome,; Italy.; Ch7 (RGSDIAG), a synthetic heptapeptide derived from a conserved region of HIV p24 (aa 232-238), was previously shown to suppress antigen-induced responses in cultures of normal human peripheral blood lymphocytes (PBL). We show in this paper that Ch7 is the shortest peptide retaining full inhibitory capacity. Further,
Human immunodeficiency virus-1 reverse transcriptase immunodominant CD4+ T cell epitopes: a peptide-based multiparametric assessment in the mouse.: Eur J Immunol. 1994 Jul;24(7):1496-502. Unique Identifier : AIDSLINE MED/94298846; Borg JP; Ihlenfeldt HG; Jung G; Haas G; Pierres M; Centre d'Immunologie INSERM-CNRS de Marseille-Luminy, France.; We previously identified an immunodominant CD4+ T cell determinant in the carboxy-terminal region of HIV-1 reverse transcriptase (RT528-543). The present study aimed at enumerating all the potential sites of HIV-1 RT recognized by Th cells in the BALB/c (H-2d) mouse model. To achieve this we used a panel of 62 overlap
Modified technique for efficient detection of microsporidia.: J Clin Microbiol. 1994 Apr;32(4):1074-5. Unique Identifier : AIDSLINE MED/94299791; Kokoskin E; Gyorkos TW; Camus A; Cedilotte L; Purtill T; Ward B; McGill University Centre for Tropical Diseases, Montreal General; Hospital, Canada.; Changes in temperature (from room temperature to 50 degrees C) and staining time (from 90 to 10 min) were evaluated as a means of improving the detection of microsporidia from stool specimens. A blinded and independent comparison of 50 known positive matched-specimen pairs by three technologists resulted in consistent
[AIDS and palliative cures (editorial)]: Minerva Med. 1994 Apr;85(4):135-9. Unique Identifier : AIDSLINE MED/94301484; Fantoni M; Ricci F
Modulation of enzyme activity by antibody binding to an alkaline phosphatase-epitope hybrid protein.: Protein Eng. 1994 Apr;7(4):509-14. Unique Identifier : AIDSLINE MED/94301999; Brennan C; Christianson K; Surowy T; Mandecki W; Abbott Laboratories, IL 60064-3500.; An epitope from the HIV-1 gp120 protein V3 loop has been inserted onto the surface of bacterial alkaline phosphatase at different positions in the vicinity of the enzyme active site, creating hybrid proteins that can bind to an anti-gp120 monoclonal antibody. One of the hybrid proteins, API1, has a 13 amino acid V3 lo
Lymphocyte subset monitoring can detect xenoheart rejection in primates.: Transplant Proc. 1994 Jun;26(3):1067-9. Unique Identifier : AIDSLINE MED/94302682; Kawauchi M; Fukushima N; Gundry SR; de Begona JA; Nehlsen-Cannarella S; Bailey LL; Department of Surgery, Loma Linda University Medical Center, CA; 92354.
Patterns of HIV-1 mRNA expression in transgenic mice are tissue-dependent.: Virology. 1994 Aug 1;202(2):940-8. Unique Identifier : AIDSLINE MED/94303209; Bruggeman LA; Thomson MM; Nelson PJ; Kopp JB; Rappaport J; Klotman PE; Klotman ME; Viral Pathogenesis Unit, National Institute of Dental Research,; National Institutes of Health, Bethesda, Maryland 20892.; To explore tissue-specific factors that may be important in HIV-1 transcriptional and post-transcriptional regulation, we examined a transgenic mouse model containing a mutant provirus deleted in the gag and pol region. The level of transgene expression was tissue-dependent. Skin, muscle, and tail consistently express
New developments in the chemotherapy of lentivirus (human immunodeficiency virus) infections: sensitivity/resistance of HIV-1 to non-nucleoside HIV-1-specific inhibitors.: Ann N Y Acad Sci. 1994 Jun 6;724:438-56. Unique Identifier : AIDSLINE MED/94304039; de Clercq E; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.; Of the different steps of the HIV replicative cycle, the reverse transcription step has received most attention as a target for chemotherapeutic intervention. The reverse transcriptase (RT) can be blocked by both nucleoside (nucleotide) and non-nucleoside type of inhibitors. Whereas the former act as competitive inhib
Preclinical evaluation of MKC-442, a highly potent and specific inhibitor of human immunodeficiency virus type 1 in vitro.: Antimicrob Agents Chemother. 1994 Apr;38(4):688-92. Unique Identifier : AIDSLINE MED/94304110; Baba M; Shigeta S; Yuasa S; Takashima H; Sekiya K; Ubasawa M; Tanaka H; Miyasaka T; Walker RT; De Clercq E; Department of Microbiology, Fukushima Medical College, Japan.; MKC-442 (6-benzyl-1-ethoxymethyl-5-isopropyluracil or I-EBU) has recently been identified as a highly potent and specific inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Since the compound has favorable pharmacokinetic and toxicity profiles in vivo, we have evaluated MKC-442 for its inh
Effect of oxetanocin G, a novel nucleoside analog, on DNA synthesis by hepatitis B virus virions.: Antimicrob Agents Chemother. 1994 Apr;38(4):707-12. Unique Identifier : AIDSLINE MED/94304113; Nagahata T; Kitagawa M; Matsubara K; Institute for Molecular and Cellular Biology, Osaka University,; Japan.; The novel nucleoside oxetanocin G, 9-(2-deoxy-2-hydroxymethyl-beta-D-erythro-oxetanosyl)guanine (OXT-G), that is a derivative of oxetanocin A, was studied in relation to its action on the synthesis of hepatitis B virus (HBV) DNA and cellular DNA in an HBV-producing cell line, HB611 (T. Tsurimoto, A. Fujiyama, and K. M
Influence of stereochemistry on antiviral activities and resistance profiles of dideoxycytidine nucleosides.: Antimicrob Agents Chemother. 1994 Apr;38(4):868-71. Unique Identifier : AIDSLINE MED/94304142; Van Draanen NA; Tisdale M; Parry NR; Jansen R; Dornsife RE; Tuttle JV; Averett DR; Koszalka GW; Division of Experimental Therapy, Burroughs Wellcome Co.,; Research Triangle Park, North Carolina 27709.; beta-L-2 ,3 -Dideoxycytidine (beta-L- ddC ) and beta-L-5-fluoro-2 ,3 -dideoxycytidine (5-F-beta-L-ddC) were prepared and shown to have potent activity against human immunodeficiency virus type 1 (HIV-1) and hepatitis B virus (HBV). These compounds were
The genetic and functional basis of HIV-1 resistance to nonnucleoside reverse transcriptase inhibitors.: Arch Virol Suppl. 1994;9:11-7. Unique Identifier : AIDSLINE MED/94305388; Emini EA; Byrnes VW; Condra JH; Schleif WA; Sardana VV; Merck Research Laboratories, West Point, Pennsylvania.; The nonnucleoside reverse transcriptase (RT) inhibitors are structurally diverse compounds that are specific inhibitors of the human immunodeficiency virus type 1 RT enzyme. The compounds are largely functionally identical and bind to a common site in the enzyme. HIV-1 variants that exhibit reduced susceptibility to t
Inhibition of HIV replication by CD8+ T cells correlates with CD4 counts and clinical stage of disease.: Clin Exp Immunol. 1994 Jul;97(1):68-75. Unique Identifier : AIDSLINE MED/94306755; Gomez AM; Smaill FM; Rosenthal KL; Department of Pathology, McMaster University Health Sciences; Center, Hamilton, Ontario, Canada.; We sought to evaluate the relationship of CD8+ T cell-mediated inhibition of autologous HIV replication in vitro to disease stage in HIV+ individuals. Depletion of CD8+ T cells from peripheral blood lymphocytes of 16 HIV+ subjects increased the percentage of virus-producing cultures from 56% to 81%. CD4+ T cells were
[A synthetic peptide-based immunoenzyme test system for the joint detection of human retrovirus (HTLV-1 and HIV-1) antibodies]: Gematol Transfuziol. 1993 May;38(5):36-9. Unique Identifier : AIDSLINE MED/94307568; Rasuli AM; Klepikov NN; Gurtsevich VE; Andreev SM; Meshcheriakova DV; Rasuli ShM; The study was made to develop an immunodiagnostic test system based on synthetic peptides able to detect in the same assay the total concentration of heterospecific antibodies against human retroviruses HTLV-1 and HIV-1. Three panels of reference-sera contained antibodies to HTLV-1 (70 specimens), HIV-1 (50 and 16 spe
HIV-1 gp41 shares a common immunologic determinant with human T, B and monocyte cell lines.: Immunol Lett. 1994 Mar;39(3):219-22. Unique Identifier : AIDSLINE MED/94307758; Chen YH; Susanna A; Bock G; Steindl F; Katinger H; Dierich MP; Ludwig-Boltzmann-Institute for AIDS-Research, Innsbruck, Austria.; Several examples of molecular mimicry between HIV-1 and human proteins are reported in the literature. Here we report on yet another example. The monoclonal antibody 3D6 recognized a 17-amino-acid region in HIV-1 gp41 (amino acids 602-618) and could bind to the human T-cell lines H9 and Molt4, B cell lines Raji and Bj
Mutagenesis of the conserved aspartic acid 443, glutamic acid 478, asparagine 494, and aspartic acid 498 residues in the ribonuclease H domain of p66/p51 human immunodeficiency virus type I reverse transcriptase. Expression and biochemical analysis.: J Biol Chem. 1994 Jul 29;269(30):19245-9. Unique Identifier : AIDSLINE MED/94308199; Mizrahi V; Brooksbank RL; Nkabinde NC; Molecular Biology Unit, South African Institute for Medical; Research, Johannesburg.; The effects of point mutations of the conserved Asp443, Glu478, Asn494, and Asp498 residues in the RNase H domain of human immunodeficiency virus type I (HIV-1) reverse transcriptase (RT) have been analyzed. The mutants fell into two classes: (i) functional RT, but not detectable ribonuclease H activity, and (ii) unch
Conjugation of recombinant reverse transcriptase of HIV-1 to beta-D-galactosidase from Escherichia coli for ultrasensitive enzyme immunoassay (immune complex transfer enzyme immunoassay) of anti-HIV-1 IgG.: J Immunol Methods. 1994 Jun 24;172(2):179-87. Unique Identifier : AIDSLINE MED/94308543; Hashinaka K; Hashida S; Saitoh A; Nakata A; Shinagawa H; Oka S; Shimada K; Ishikawa E; Department of Biochemistry, Medical College of Miyazaki, Japan.; Recombinant reverse transcriptase (RT) of HIV-1 was conjugated to beta-D-galactosidase from Escherichia coli in three different ways. M