Acquired immunodeficiency syndrome in the elderly. NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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Acquired immunodeficiency syndrome in the elderly.

Drugs Aging. 1994 May;4(5):410-6. Unique Identifier : AIDSLINE MED/94319076
Adler WH; Nagel JE; Clinical Immunology Section, National Institute on Aging,; National Institutes of Health, Baltimore, Maryland.

Abstract: Recent data from the US show that since 1990 the number of paediatric patients with AIDS is decreasing while the number of patients with AIDS over age 50 years is increasing. To date, little attention has been given to understanding AIDS risk-taking behaviours, clinical presentations, and therapeutic needs of middle-aged and older HIV-infected individuals. Older HIV-infected individuals deteriorate more rapidly than younger patients due to an accelerated loss of CD4+ helper T cells. Despite recognised age-related physiological differences between young and elderly individuals, scant information about drug optimisation for the treatment of AIDS in older individuals is available. More data need to be collected about this group of AIDS patients, and appropriate treatment strategies designed for their special needs.
Keywords: Acquired Immunodeficiency Syndrome/DRUG THERAPY/*EPIDEMIOLOGY/ ETIOLOGY/*IMMUNOLOGY Aged Aging/*IMMUNOLOGY/PHYSIOLOGY Blood Transfusion/ADVERSE EFFECTS Human Immunity, Cellular Prognosis Social Isolation Zidovudine/ADVERSE EFFECTS JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL

KWDacquiredimmunodeficiencysyndrome/drugtherapy/KWDepidemiology/etiology/KWDimmunologyagedaging/KWDimmunology/physiologybloodtransfusion/adverseeffectshumanimmunity,cellularprognosissocialisolationzidovudine/adverseeffectsjournalarticlereviewreview,tutorial
941130
M94B0745

Copyright © 1994 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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