Duration of illness and neuropsychological performance in asymptomatic HIV infection. NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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Duration of illness and neuropsychological performance in asymptomatic HIV infection.

J Neuropsychiatry Clin Neurosci. 1994 Spring;6(2):160-4. Unique Identifier : AIDSLINE MED/94319177
Bornstein RA; Nasrallah HA; Para MF; Whitacre CC; Fass RJ; Department of Psychiatry, Ohio State University College of; Medicine, Columbus.

Abstract: The relationship between duration of illness and neuropsychological performance was examined in 25 asymptomatic HIV-infected men with an estimated date of seroconversion. Mean duration of illness was approximately 2 years. After controlling for CD4 level at the time of neuropsychological examination, duration of illness was correlated with measures of visual attention, mental flexibility, dexterity, auditory information processing, and response fluency, as well as an overall measure of neuropsychological performance. Although these patients performed within normal limits, these data suggest that duration of infection may be related to subtle alterations in neuropsychological performance. These results are discussed with regard to possible mechanisms that implicate gradual accumulation of neurotoxins.
Keywords: Adult AIDS Dementia Complex/*DIAGNOSIS/IMMUNOLOGY/PSYCHOLOGY Bisexuality/PSYCHOLOGY CD4-CD8 Ratio Follow-Up Studies Homosexuality/PSYCHOLOGY Human HIV Infections/*DIAGNOSIS/IMMUNOLOGY/PSYCHOLOGY HIV Seropositivity/*DIAGNOSIS/IMMUNOLOGY/PSYCHOLOGY Longitudinal Studies Male Middle Age *Neuropsychological Tests Support, U.S. Gov't, P.H.S. Time Factors JOURNAL ARTICLE

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941130
M94B0741

Copyright © 1994 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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