Screening of blood donations for HIV-1 antibody: 1985-1991.

Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

Screening of blood donations for HIV-1 antibody: 1985-1991.

CDR (Lond Engl Rev). 1991 Dec 6;1(13):R144-6. Unique Identifier : AIDSLINE MED/94138434
Gunson HH; Rawlinson VI; North Western Regional Transfusion Centre, Manchester.

Abstract: One hundred and ninety HIV-1 antibody positive donors have been detected, out of 14.85 million blood donations screened in the United Kingdom and the Isle of Man, since the start of testing in October 1985 to the end of March 1991. There were 145 men and 45 women, with an overall seropositivity rate of 0.001%. Records for new donors (ie, those donating for the first time) have been kept since February 1986 and 79 out of 1.9 million donations have been seropositive (58 men and 21 women); a rate of 0.004%. One hundred and forty-one (74.2%) of the 190 positive donors were found to have been exposed to a high risk of HIV infection. Twenty-four (13%) denied any exposure other than heterosexual intercourse with partners who were not considered to be at high risk. In six cases the partners were from countries where the main route of transmission is heterosexual. Seven donors (4%) attributed infection to some other cause. Eighteen (9.5%) have been lost to follow-up, are still being investigated or have not yet been interviewed. Combined tests which screen for both HIV-1 and HIV-2 antibodies were introduced in June 1990. The last 2.55 million donations (including 370,000 new donors) have been tested with these kits. One HIV-2 antibody positive donation had been confirmed in a new donor by the end of March 1991.(ABSTRACT TRUNCATED AT 250 WORDS)

Keywords: Adult *Blood Donors England/EPIDEMIOLOGY Female Human HIV Antibodies/*ANALYSIS HIV Infections/*PREVENTION & CONTROL/TRANSMISSION HIV Seropositivity/EPIDEMIOLOGY/TRANSMISSION HIV-1/*IMMUNOLOGY HIV-2/*IMMUNOLOGY Male *Mass Screening Risk Factors JOURNAL ARTICLE
940530
M9450879

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1994. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1994. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .