Short communication: possible activity of beta-carotene in patients with the AIDS related complex. A pilot study. NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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Short communication: possible activity of beta-carotene in patients with the AIDS related complex. A pilot study.

Med Oncol Tumor Pharmacother. 1992;9(3):151-3. Unique Identifier : AIDSLINE MED/94076882
Bianchi-Santamaria A; Fedeli S; Santamaria L; Camillo Golgi Institute of General Pathology, Centro Tumori,; University of Pavia, Italy.

Abstract: In a pilot single blind study, beta-carotene (BC) supplementation produced, in ARC patients under current treatment, apparent recovery from asthenia, fever, nocturnal sweating, diarrhoea, loss in weight, and led as a result to an improvement in general health and working efficiency, but not to an improvement in multiple district lympho-adenopathies. Nevertheless, BC appeared to prevent progress to AIDS and, in addition, to lower the effective dosage of AZT used in one case of ARC developed into AIDS, producing a recovery from opportunistic infections and an inhibition of Kaposi sarcoma diffusion, in line with a two-fold rise in CD4 counts.
Keywords: Acquired Immunodeficiency Syndrome/PREVENTION & CONTROL Adult AIDS-Related Complex/BLOOD/*DRUG THERAPY Carotene/*THERAPEUTIC USE CD4-Positive T-Lymphocytes/DRUG EFFECTS Female Human Leukocyte Count/DRUG EFFECTS Male Pilot Projects Single-Blind Method CLINICAL TRIAL JOURNAL ARTICLE RANDOMIZED CONTROLLED TRIALKWDacquiredimmunodeficiencysyndrome/prevention&controladultaids-relatedcomplex/blood/KWDdrugtherapycarotene/KWDtherapeuticusecd4-positivet-lymphocytes/drugeffectsfemalehumanleukocytecount/drugeffectsmalepilotprojectssingle-blindmethodclinicaltrialjournalarticlerandomizedcontrolledtrial
940330
M9431004

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