Relative performance of Organon kit in comparison to Du Pont for confirmatory serological testing of HIV infection by western blot test in sera from blood donors. NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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Relative performance of Organon kit in comparison to Du Pont for confirmatory serological testing of HIV infection by western blot test in sera from blood donors.

J Commun Dis. 1992 Jun;24(2):78-81. Unique Identifier : AIDSLINE MED/94186635
Aggarwal RK; Chatterjee R; Chattopadhya D; Kumari S; National Institute of Communicable Diseases, Sham Nath Marg,; Delhi.


Abstract: A total of 32 specimens with different categories of reactivity by Du Pont Western Blot kit comprising of specimens showing full spectrum of HIV-I antigen specific bands, 19 specimens showing total absence of bands and four specimens showing non-specific bands (without any interpretative importance) were subjected to Western Blot testing by Organon test. Of the nine specimens showing full spectrum of bands by Du Pont the correlation with Organon kit was 100 per cent based on WHO criteria. Four specimens with non-specific indeterminate band pattern by Du Pont failed to show any band in Organon kit, indicating that latter to be more specific.
Keywords: AIDS Serodiagnosis/*METHODS Blood Donors Blotting, Western/*METHODS Comparative Study Enzyme-Linked Immunosorbent Assay Evaluation Studies Human HIV Infections/*BLOOD/EPIDEMIOLOGY/PREVENTION & CONTROL *HIV-1 Mass Screening/METHODS Reagent Kits, Diagnostic/*STANDARDS Sensitivity and Specificity JOURNAL ARTICLEKWDaidsserodiagnosis/KWDmethodsblooddonorsblotting,western/KWDmethodscomparativestudyenzyme-linkedimmunosorbentassayevaluationstudieshumanhivinfections/KWDblood/epidemiology/prevention&controlKWDhiv-1massscreening/methodsreagentkits,diagnostic/KWDstandardssensitivityandspecificityjournalarticle
940630
M9460879

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