Gastrointestinal and genitourinary tract tumors in patients at risk or with HIV infection (Meeting abstract).

Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

Gastrointestinal and genitourinary tract tumors in patients at risk or with HIV infection (Meeting abstract).

Third Annual Pittsburgh Cancer Conference. November 19-20, 1992. Pittsburgh, PA, p. 10, 1992.. Unique Identifier : AIDSLINE ICDB/94698060
Douglas D; Patel A; Wolf B; Remick S; Albany Medical Coll., Albany, NY 12208

Abstract: AIDS-defining neoplasms include Kaposi's sarcoma, primary central nervous system lymphoma, and non-Hodgkin's lymphoma. As we enter the second decade of the HIV epidemic, it is apparent that other solid tumors are seen in these patients (pts) as well. The AIDS Program of the Albany Medical Center has an active pt census of over 1000 patients. We have recently identified 22 pts with solid tumors other than AIDS-defining neoplasms, 2% prevalence. Of the 22 pts, 6 developed gastrointestinal and genitourinary tract tumors (2 colon, 1 anus, 1 liver, 1 bladder and 1 kidney). All pts had positive HIV serology or known risk behavior for HIV infection at time of cancer diagnosis. There were 5 men and 1 woman; median age 45 yrs (range 32 to 54 yrs); and risk behavior: 4 IVDU, 1 homosexual, and 1 had no apparent risk. Five of 6 pts had pathological confirmation of malignancy; the pt with hepatoma had space-occupying liver lesions and an elevated AFP. Four pts died at 3, 17, 22, and 24 mo after cancer diagnosis. In three, progressive cancer was the major cause of death and, in one, progressive HIV infection was the contributing factor. Two pts remain alive at 6 and 33 mo following treatment for their cancer. As the HIV epidemic advances and pts live longer as a result of improvements in therapy, we might anticipate seeing more solid tumors other than AIDS-defining neoplasms in our pts.

Keywords: Female Gastrointestinal Neoplasms/*COMPLICATIONS Human HIV Infections/*COMPLICATIONS Male Middle Age Risk Factors Sex Behavior Substance Abuse, Intravenous Urogenital Neoplasms/*COMPLICATIONS ABSTRACT
940730
M9470930

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1994. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1994. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .