AIDS animal models program.

Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

AIDS animal models program.

Symp Nonhum Primate Models AIDS. 1993 Sep 19-22;11:abstract no. 108. Unique Identifier : AIDSLINE PRIM11/94191594
April M; NIH, DHHS, Bethesda, Maryland 20892.

Abstract: AIDS ANIMAL MODELS PROGRAM: The AIDS Animal Models Program promotes the characterization and validation of existing models, expands development of new models, and coordinates these common interests with other NIH institutes. Basic and clinical research on AIDS-related diseases has been greatly accelerated by the development of nonhuman primate models that are susceptible to human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infection and show, both serologically and clinically, the symptoms observed in human AIDS. It is now possible to conduct basic research on AIDS in nonhuman primate models with a high degree of confidence that the studies are directly applicable to the human syndrome. CHIMPANZEE BREEDING AND RESEARCH PROGRAM: The Chimpanzee Breeding and Research Program (CBRP) is a first and only national program to combine the expertise and experience of both chimpanzees for investigations of important human health problems, including viral hepatitis and AIDS. The AIDS Animal Models Program administers this important resource, and the CBRP Management Committee provides oversight and advice. SPECIFIC-PATHOGEN-FREE MACAQUE BREEDING AND RESEARCH PROGRAM: SIV research in macaques is of critical importance to the concerted AIDS research effort. The Comparative Medicine Program's specific-pathogen-free (SPF) macaque breeding colonies are currently in their fifth year of development. Characterization and demographic status of the SPF colonies have been determined, and it is now possible to estimate the production rate over the next 5 to 6 years.

Keywords: *Acquired Immunodeficiency Syndrome Animal Chimpansee troglodytes *Disease Models, Animal Human HIV Macaca National Institutes of Health (U.S.) Primates Research/TRENDS *Simian Acquired Immunodeficiency Syndrome Specific Pathogen-Free Organisms SIV United States ABSTRACT
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