Total and specific IgE in sera of HIV positive and HIV negative homosexual male (regulation of IgE synthesis in HIV infection). NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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Total and specific IgE in sera of HIV positive and HIV negative homosexual male (regulation of IgE synthesis in HIV infection).

Acta Biomed Ateneo Parmense. 1992;63(1-2):133-45. Unique Identifier : AIDSLINE MED/94055518
Horvath A; Department of Dermatology and Venereology, Semmelweis University; of Medical Sciences.

Abstract: In the course of HIV infection atopic symptoms can often be experienced (atopic dermatitis, asthmatic like symptoms in upper respiratory tract, sensitivity to drugs). Total IgE increase has been detected which is in inverse correlation with CD4 positive lymphocytes. Using semi quantitative and quantitative methods total and specific IgE levels of 30 HIV positive and 30 HIV negative homosexual men without atopic anamnestic data and symptoms have been determined. The age matched control groups were of 30 atopic men with active symptoms and 30 healthy, HIV negative heterosexual men. Determination of CD4, CD8 positive number of lymphocytes as well as B-2 microglobulin have been carried out. Total IgE level of HIV positive and HIV negative homosexuals was higher than that of the healthy controls and lower than that of the atopic controls. Specific IgE-s have been found more often in HIV positive and HIV negative homosexuals than in the normal controls. The correlation among CD4 and CD8 positive lymphocytes, and B-2 microglobulin level and total IgE level was not significant.
Keywords: Acquired Immunodeficiency Syndrome/*IMMUNOLOGY Adult Antibody Formation Antigens/IMMUNOLOGY Case Report Comparative Study Food Hypersensitivity/IMMUNOLOGY *Homosexuality Human HIV Seropositivity/BLOOD/*IMMUNOLOGY IgE/*BIOSYNTHESIS/BLOOD/IMMUNOLOGY Lymphocytes/IMMUNOLOGY Male JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/KWDimmunologyadultantibodyformationantigens/immunologycasereportcomparativestudyfoodhypersensitivity/immunologyKWDhomosexualityhumanhivseropositivity/blood/KWDimmunologyige/KWDbiosynthesis/blood/immunologylymphocytes/immunologymalejournalarticle
940228
M9420798

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