HIV and human complement: mechanisms of interaction and biological implication. NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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HIV and human complement: mechanisms of interaction and biological implication.

Immunol Today. 1993 Sep;14(9):435-40. Unique Identifier : AIDSLINE MED/94030466
Dierich MP; Ebenbichler CF; Marschang P; Fust G; Thielens NM; Arlaud GJ; Institut fur Hygiene, Leopold Franzens Universitat, Innsbruck,; Austria.

Abstract: Human complement, although not lytic for HIV-1, interacts with the virus and is closely involved in the infectious process. It enhances infection in the absence of antibody, and turns neutralizing antibodies into agents which increase viral infectivity. In this review M.P. Dierich et al. summarize available information and discuss possible biological implications.
Keywords: Animal Complement/*IMMUNOLOGY Complement Activation/IMMUNOLOGY Complement Hemolytic Activity Assay Human HIV Antibodies/IMMUNOLOGY HIV Infections/IMMUNOLOGY HIV-1/*IMMUNOLOGY Support, Non-U.S. Gov't JOURNAL ARTICLE REVIEW REVIEW, TUTORIALKWDanimalcomplement/KWDimmunologycomplementactivation/immunologycomplementhemolyticactivityassayhumanhivantibodies/immunologyhivinfections/immunologyhiv-1/KWDimmunologysupport,non-uKWDsKWDgov'tjournalarticlereviewreview,tutorial
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Copyright © 1994 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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