Immunotherapeutic strategies in the treatment of HIV infection and AIDS. NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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Immunotherapeutic strategies in the treatment of HIV infection and AIDS.

Curr Opin Immunol. 1993 Aug;5(4):600-7. Unique Identifier : AIDSLINE MED/94030705
Birx DL; Redfield RR; Department of Retroviral Research, Walter Reed Army Institute of; Research, Washington D.C. 20307-5100.

Abstract: The immune response against HIV does not result in complete viral clearance. Recent interventions have focused on novel strategies to modify human anti-HIV immunity. Active vaccination of patients with HIV infection (vaccine therapy) safely alters the immune repertoire against HIV. This unique approach will provide insight into the immunoregulatory consequences of HIV-specific innate and adaptive immune responses, and hopefully define the immunological Achilles heel of HIV. Once defined, researchers, aided by current biotechnological techniques, can rationally design future vaccines and immune based therapeutic products.
Keywords: Acquired Immunodeficiency Syndrome/*THERAPY AIDS Vaccines Human HIV Infections/*THERAPY HIV-1/GROWTH & DEVELOPMENT Immunization *Immunotherapy Virus Replication/IMMUNOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIALKWDacquiredimmunodeficiencysyndrome/KWDtherapyaidsvaccineshumanhivinfections/KWDtherapyhiv-1/growth&developmentimmunizationKWDimmunotherapyvirusreplication/immunologyjournalarticlereviewreview,tutorial
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M9420776

Copyright © 1994 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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