HIV related Mycobacterium tuberculosis (M.Tb) at Fairfield Hospital. NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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HIV related Mycobacterium tuberculosis (M.Tb) at Fairfield Hospital.

Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:32 (abstract no. FC1). Unique Identifier : AIDSLINE ASHM5/94348956
Wright EJ; Sarr A; Dwyer B; Hoy J; Fairfield Hospital, Vic.

Abstract: OBJECTIVE: To review the clinical and laboratory features, management and outcome of M.tuberculosis in 18 HIV seropositive patients (2.5% of the total AIDS patients). METHODS: A retrospective review of case records and laboratory results of 16 male and 2 female patients attending Fairfield Hospital between January 1985 and June 1993. The median age at presentation was 35 years (25-61 years) and 6 patients (33%) had no identifiable risk factors for TB. In 13/18 patients (72%), TB was the AIDS defining illness. There was less delay in the diagnosis of pulmonary TB than extrapulmonary TB (see table). 4/18 were treated presumptively for MAC infection prior to isolation of M.Tb. All isolates were fully sensitive to standard TB drugs and treatment was well tolerated. 9/18 patients have died and the median survival in the 8/9 patients diagnosed antemortem was 949 days (R173-1,724 days). CONCLUSION: TB occurs in advanced HIV disease, the diagnosis may be delayed, treatment is well tolerated and median survival is greater than 2.5 years. TABULAR DATA, SEE ABSTRACT VOLUME.
Keywords: Adult AIDS-Related Opportunistic Infections/DIAGNOSIS/*EPIDEMIOLOGY Cross-Sectional Studies Female Human Incidence Male Middle Age Retrospective Studies Tuberculosis, Pulmonary/DIAGNOSIS/*EPIDEMIOLOGY Victoria/EPIDEMIOLOGY ABSTRACTKWDadultaids-relatedopportunisticinfections/diagnosis/KWDepidemiologycross-sectionalstudiesfemalehumanincidencemalemiddleageretrospectivestudiestuberculosis,pulmonary/diagnosis/KWDepidemiologyvictoria/epidemiologyabstract
941230
M94C4271

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