A case of HIV-2 infection in Victoria.

Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

A case of HIV-2 infection in Victoria.

Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:35 (abstract no. SC2). Unique Identifier : AIDSLINE ASHM5/94348962
Breschkin A; Russell D; Crofts N; Locarnini S; Victorian Infectious Diseases Reference Laboratory, Fairfield; Hospital.

Abstract: In June 1993 a serum sample from a high-risk patient was referred to the Victorian HIV Reference Laboratory at Fairfield Hospital for routine anti-HIV testing. The serum was repeatedly reactive (S/C0 = 3.7) by the Abbott HIV-1/HIV-2 EIA. Confirmatory testing by HIV-1 Western blot showed an indeterminate profile with moderate-weak reactivity to P24, P34 and P55. The serum was strongly reactive to HIV-2 in the Genetic Systems GENIE synthetic envelope peptide assay and was non-reactive to HIV-1. The specimen was confirmed positive by HIV-2 Western blot at the National Reference Laboratory, showing reactivity to all HIV-2 bands. The serum was non-reactive by the Wellcome HIV-1 EIA and the AGEN HIV-1 SimpliRED assay. Retrospective testing of a July 1991 serum from the patient was non-reactive in the HIV-1/HIV-2 ELA. Although HIV-2 infection is extremely rare in Australia, this case illustrates that the potential for its spread obviously exists. It is reassuring that Australian diagnostic and blood bank laboratories are now using screening assays capable of detecting HIV-1 and HIV-2 infection.

Keywords: *AIDS Serodiagnosis Blotting, Western Human HIV Infections/*DIAGNOSIS/PREVENTION & CONTROL/TRANSMISSION *HIV-2 Immunoenzyme Techniques ABSTRACT
941230
M94C4265

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