[Syndrome of macrophagic activation with hemophagocytosis in human immunodeficiency virus infection] NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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[Syndrome of macrophagic activation with hemophagocytosis in human immunodeficiency virus infection]

Rev Med Interne. 1992 Nov;13(6):438-40. Unique Identifier : AIDSLINE MED/94225092
Pellegrin JL; Merlio JP; Lacoste D; Barbeau P; Brossard G; Beylot J; Leng B; Clinique de Medecine Interne et Maladies Infectieuses, Hopital; Saint-Andre, Bordeaux.


Abstract: The authors report two cases of hematophagic histiocytosis in HIV positive patients. In the first case, a patient with Kaposi sarcoma and Mycobacterium avium infection had a rapidly deteriorating course with progressive pancytopenia and death, as generally described in the literature. In the second case, hematophagic histiocytosis appeared during HIV primo infection and reversed spontaneously. Although few cases of hemophagocytic syndrome have been reported in HIV positive patient, it could represent an underestimated cause of pancytopenia. Both opportunistic microorganisms and HIV are able to cause hematophagic histiocytosis.
Keywords: Adult Case Report English Abstract Fatal Outcome Histiocytosis, Non-Langerhans-Cell/BLOOD/*MICROBIOLOGY Human HIV Infections/CLASSIFICATION/*COMPLICATIONS *HIV-1 *Macrophage Activation Male Pancytopenia/BLOOD/ETIOLOGY Remission, Spontaneous JOURNAL ARTICLE REVIEW REVIEW OF REPORTED CASESKWDadultcasereportenglishabstractfataloutcomehistiocytosis,non-langerhans-cell/blood/KWDmicrobiologyhumanhivinfections/classification/KWDcomplicationsKWDhiv-1KWDmacrophageactivationmalepancytopenia/blood/etiologyremission,spontaneousjournalarticlereviewreviewofreportedcases
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Copyright © 1994 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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