Viruses and cancer. Causal associations. NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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Viruses and cancer. Causal associations.

Ann Epidemiol. 1990 Oct;1(1):71-92. Unique Identifier : AIDSLINE MED/94093735
Evans AS; Mueller NE; Yale University School of Medicine, New Haven, CT.

Abstract: This review first considered some general problems in establishing causal links between a virus and a human cancer and offered some guidelines in the pursuit of this objective. Second, it reviewed the current causal associations for several candidate oncogenic viruses in relation to the tumors with which they are associated. These include Epstein-Barr virus in relation to Burkitt's lymphoma, nasopharyngeal carcinoma, Hodgkin's disease, and non-Hodgkin's lymphoma; hepatitis B and C viruses in relation to hepatocellular carcinoma; human T-cell leukemia/lymphoma virus type 1 and atypical leukemia/lymphoma; and human papilloma viruses in relation to cervical carcinoma. For some, the causal relationship is strong: hepatitis B virus with hepatocellular carcinoma, and human T-cell leukemia/lymphoma virus with adult T-cell leukemia/lymphoma. For one, the causal relationship is moderate: Epstein-Barr virus with African Burkitt's lymphoma. For others it is incomplete or inconclusive: Epstein-Barr virus with Hodgkin's disease and non-Hodgkin's lymphoma, and hepatitis C virus with hepatocellular carcinoma. Current techniques do not permit an answer for some: human papilloma virus with cervical carcinoma.
Keywords: Animal Hepatitis B Virus Hepatitis C Viruses Herpesvirus 4, Human Human HTLV-I Neoplasms/*ETIOLOGY Tumor Virus Infections/*ETIOLOGY Virus Diseases/*COMPLICATIONS JOURNAL ARTICLE REVIEW REVIEW, ACADEMICKWDanimalhepatitisbvirushepatitiscvirusesherpesvirus4,humanhumanhtlv-ineoplasms/KWDetiologytumorvirusinfections/KWDetiologyvirusdiseases/KWDcomplicationsjournalarticlereviewreview,academic
940430
M9440911

Copyright © 1994 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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