[Paracoccidioides brasiliensis (Lutz, 1908) isolated by hemoculture in a patient with the acquired immunodeficiency syndrome (AIDS)] NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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[Paracoccidioides brasiliensis (Lutz, 1908) isolated by hemoculture in a patient with the acquired immunodeficiency syndrome (AIDS)]

Rev Inst Med Trop Sao Paulo. 1992 Nov-Dec;34(6):565-7. Unique Identifier : AIDSLINE MED/94098187
Hadad DJ; Pieres M de F; Petry TC; Orozco SF; Melhem M de S; Paes RA; Gianini MJ; Centro de Referencia e Treinamento--AIDS, Sao Paulo, Brasil.

Abstract: A case of an AIDS patient with positive blood culture for Paracoccidiodes brasiliensis is reported. The patient was a 29-years-old male born in Nova Londrina (Parana State, Brazil) who presented splenomegaly and fever of unknown origin. Three blood cultures were performed, each one of them for aerobic bacteria, mycobacteria and fungi. Cultures for aerobic bacteria and mycobacteria were negative. However, the yeast phase P. brasiliensis was isolated from two cultures in BHI agar, 20 days after inoculation in Negroni medium. The patient was classified in group V according to the Centers for Disease Control (CDC) criteria for AIDS, due to a Pneumocystis carinii pneumonia. Treatment was discontinued due to an individual decision of the patient on the second dose of amphotericin B. This antibiotic was replaced by ketoconazole in the daily dose of 800 mg. The patient died one year after the isolation of P. brasiliensis on blood culture.
Keywords: Adult Amphotericin B/ADMINISTRATION & DOSAGE AIDS-Related Opportunistic Infections/DRUG THERAPY/*MICROBIOLOGY Case Report English Abstract Fungemia/DRUG THERAPY/*MICROBIOLOGY Human Ketoconazole/ADMINISTRATION & DOSAGE Male Paracoccidioides/*ISOLATION & PURIF Paracoccidioidomycosis/DRUG THERAPY/*MICROBIOLOGY Treatment Refusal JOURNAL ARTICLEKWDadultamphotericinb/administration&dosageaids-relatedopportunisticinfections/drugtherapy/KWDmicrobiologycasereportenglishabstractfungemia/drugtherapy/KWDmicrobiologyhumanketoconazole/administration&dosagemaleparacoccidioides/KWDisolation&purifparacoccidioidomycosis/drugtherapy/KWDmicrobiologytreatmentrefusaljournalarticle
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