Evaluation of anti-HTLV-1 in physical-checkup individuals and blood donors in Taiwan. NLM AIDSLINE Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

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Evaluation of anti-HTLV-1 in physical-checkup individuals and blood donors in Taiwan.

Chung Hua Min Kuo Wei Sheng Wu Chi Mien I Hsueh Tsa Chih. 1992 Nov;25(4):244-51. Unique Identifier : AIDSLINE MED/94109187
Yung CH; Chow MP; Hu HY; Tzeng JL; Wu YS; Lyou JY; Liu WT; Blood bank, Department of Medicine, Veterans General Hospital,; National Yang-Ming Medical College, Taipei, Taiwan, Republic of; China.


Abstract: The gelatin particle agglutination (GPA) test specific for antibody detection of human T-cell lymphotropic virus type 1 (HTLV-1) was used to screen 500 blood donors and 5000 physical-checkup individuals at Veterans General Hospital-Taipei. The positive rate of physical-checkup individuals and the blood donors was 0.18% (9/5000) and 0% (0/5000) respectively. Among the 9 GPA positive specimens, eight were confirmed to be positive by western blot analysis and a prevalence rate of 0.16% (8/5000). Seven of the nine GPA positive samples were also positive by indirect fluorescent antibody test and two of them had indeterminate results. Since GPA is less expensive, relatively simple and convenient, we recommend that GPA could be used as screening test for HTLV-1 infection of blood donors, followed by western blot method as a confirmatory test in blood bank.
Keywords: Adolescence Adult Aged Agglutination Tests *Blood Donors Blotting, Western Carrier State/EPIDEMIOLOGY/IMMUNOLOGY Female Fluorescent Antibody Technique Human HTLV-I Antibodies/*ANALYSIS HTLV-I Infections/EPIDEMIOLOGY/IMMUNOLOGY Male Middle Age *Physical Examination Retrospective Studies Taiwan/EPIDEMIOLOGY JOURNAL ARTICLEKWDadolescenceadultagedagglutinationtestsKWDblooddonorsblotting,westerncarrierstate/epidemiology/immunologyfemalefluorescentantibodytechniquehumanhtlv-iantibodies/KWDanalysishtlv-iinfections/epidemiology/immunologymalemiddleageKWDphysicalexaminationretrospectivestudiestaiwan/epidemiologyjournalarticle
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