Mycobacterium tuberculosis bacteremia at Cook County Hospital: a 30-month experience.

Important note: Information in this article was accurate in 1993. The state of the art may have changed since the publication date.

Mycobacterium tuberculosis bacteremia at Cook County Hospital: a 30-month experience.

Abstr Gen Meet Am Soc Microbiol. 1993;93:183 (abstract no. U-82). Unique Identifier : AIDSLINE ASM93/93291802
Fernandez J; Pulvirenti J; Wurtz R; Panovic S; Kocka F; Cook County Hospital-Rush Medical College, Chicago, IL.

Abstract: Patients with Mycobacterium tuberculosis (MTb) bacteremia are not well described. Over a 30-month period, Cook County Hospital had 497 patients with documented MTb, 68 of these had mycobacterial blood cultures done, 14 were positive. MTb constituted 21% of all mycobacterial bacteremias. All 14 were HIV-positive with an average CD4-lymphocyte count of 36; 8 had previous AIDS-defining infection. Identification required an average of 53 days. 8 had MTb also identified from sputum, 7 from an extra-pulmonary site. 2 had MTb isolated only from blood. Treatment was started an average of 10 days after admission. MTb bacteremia was not a factor in initiating treatment. 11 had clinical improvement, 3 died. MTb comprises a significant proportion of mycobacteremias in late-stage HIV disease. The delay in identification limits its clinical usefulness, however it is a non-invasive test and in some patients may be the only way to confirm the diagnosis of MTb.

Keywords: Bacteremia/*EPIDEMIOLOGY Blood/MICROBIOLOGY Chicago/EPIDEMIOLOGY Human HIV Seropositivity/COMPLICATIONS Mycobacterium tuberculosis/*ISOLATION & PURIF Sputum/MICROBIOLOGY Tuberculosis/*EPIDEMIOLOGY/ETIOLOGY ABSTRACT
930930
M9391169

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