1993

Counselling challenges of early HIV intervention. [videorecording]: [New York, N.Y.] : Burroughs Wellcome, c1992 1 videocassette : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9300897A
The:Treatment of HIV & AIDS with Chinese herbs. [videorecording]: Portland, Or. : I.T.M., 1992 1 videocassette (45 min.) : sd., col. ; 1/2 in (Health care for all ; no. 102) Unique Identifier : AIDSLINE AV/9300921A; Dharmananda S
Mycobacterium avium Complex in AIDS. [videorecording]: Secaucus, N.J. : Network for Continuing Medical Education, 1993 1 videocassette (35 min.) : sd., col. ; 1/2 in. + 1 booklet (NCME telecourse ; no. 641) Unique Identifier : AIDSLINE AV/9300908A; Cohn DL; Mycobacterium avium complex (MAC) is the most common opportunistic infection in persons with AIDS. Once thought of as an ultimately fatal complication, it can now be managed with various combinations of drugs.
HIV infection : neurologic complications. [videorecording]: [Oakland, Calif.] : Kaiser Foundation Health Plan, c1993 1 videocassette (54 min.) : sd., col. ; 1/2 in. + 1 guide (Medicine in the nineties) Unique Identifier : AIDSLINE AV/9300934A; Wolfe E
[AIDS : acquired immune deficiency syndrome.] 2. Aufl.: Munchen : Zuckschwerdt, 1985 vii, 187 p. : ill Unique Identifier : AIDSLINE CAT/9311977; Helm EB
Guide to public health practice : HTLV-III antibody testing and community approaches : recommendations from a consensus conference.: Kensington, Md. : Association of State and Territorial Health Officials Foundation, [1985] vii, 27 p (Publication ; no. 85 (Oct. 1985)) Unique Identifier : AIDSLINE CAT/9312432
AIDS and mental health.: [Pleasant Hill, Calif.] : Diablo Valley College, [1987] x, 382 p. : ill., ports Unique Identifier : AIDSLINE CAT/9311975; Daley J
AIDS, what is now known.: [Pleasant Hill, Calif.] : Diablo Valley College, [1987] 1 v. (various pagings) : ill., ports Unique Identifier : AIDSLINE CAT/9312339; Daley J
Facts about AIDS : acquired immune deficiency syndrome : an annotated hand searched bibliography and Infotrac data base file.: [Pleasant Hill, Calif.] : Diablo Valley College, [1987] 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9312415; Daley J
A:community response to AIDS.: Dallas, Tex. : Halcyon Press, 1988 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9311935
New York City strategic plan for AIDS.: [New York : City of New York, 1988] 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9312541
Reducing the impact of AIDS and other STDs.: [Adelaide, S. Aust.?] : Public and Environmental Health Division, South Australian Health Commission, [1988?] 34 p. : ill (Bulletin ; no. 2) Unique Identifier : AIDSLINE CAT/9312594; Hart G
Report. No. 1-no. 3.: Syndrome [Washington, D.C. : The Commission, 1989-1990 3 v Unique Identifier : AIDSLINE CAT/9313322
AIDS : a guide to the law.: London ; New York : Tavistock/Routledge, 1990 xiv, 192 p. : ill Unique Identifier : AIDSLINE CAT/9311498; Harris D; Haigh R
Research priorities : behavioural research : World Health Organization, Global Programme on AIDS : meeting on research priorities regarding women and AIDS, WHO, Geneva, 19-20 November 1990.: [Canberra] : Australian National University, [1990] 9 p (Health Transition working paper ; no. 6 (1990)) Unique Identifier : AIDSLINE CAT/9311836; Caldwell P
HIV infection and AIDS : a report to Congress on the USAID program for prevention and control.: Washington, D.C. : U.S. Agency for International Development, [1990] 64 p. : ill Unique Identifier : AIDSLINE CAT/9312799
HIV infection : prevention and care : a report of the NCNR Priority Expert Panel on HIV Infection.: Bethesda, Md. : U.S. Dept. of Health and Human Services, U.S. Public Health Service, National Institutes of Health, National Center for Nursing Research, 1990 x, 61 p. : ill (National nursing research agenda ; 2) Unique Identifier : AIDSLINE CAT/9312800
The:Costs and financing of care for AIDS patients : results of a cohort study in Los Angeles.: Santa Monica, CA : Rand, [1990] xi, 24 p (A Rand note ; N-3060-HCFA) Unique Identifier : AIDSLINE CAT/9313075; Pascal AH
[AIDES : solidaires.]: Paris : Editions du cerf, 1991 710 p (L'Histoire a vif, ISSN 0299-2833) Unique Identifier : AIDSLINE CAT/9311495; Hirsch E
AIDS in Australia : reconstructing the epidemic from 1980 to 1990 and predicting future trends in HIV disease.: Canberra, ACT, Australia : National Centre for Epidemiology and Population Health, Australian National University, c1991 32 p. : ill (Working paper, ISSN 1033-1557 ; no. 29 (Dec. 1991)) Unique Identifier : AIDSLINE CAT/9311497; Solomon PJ
AIDS, philosophy and beyond : philosophical dilemmas of a modern pandemic.: Aldershot, Hants, England ; Brookfield, USA : Avebury, c1991 vi, 341 p (Avebury series in philosophy) Unique Identifier : AIDSLINE CAT/9311500; Smith JW
Blood donation and human immunodeficiency virus infection : do new and regular donors present different risks?.: Canberra, A.C.T., Australia : National Centre for Epidemiology and Population Health, Australian National University, [1991] 17 p (Working paper, ISSN 1033-1557 ; no. 27 (Dec. 1991)) Unique Identifier : AIDSLINE CAT/9311515; Jones ME
Underreaction to AIDS in sub-Saharan Africa.: [Canberra] : Australian National University, [1991] 21 p (Health Transition working paper ; no. 9 (1991)) Unique Identifier : AIDSLINE CAT/9311904; Caldwell JC
[Infoscopie Alsace : bulletin trimestriel d'information sur la sante publique.] No 1 (mars 1991)-: Strasbourg : D.D.A.S.S. du Bas-Rhin ; Colmar : D.D.A.S.S. du Haut-Rhin, [1991- v. : ill Unique Identifier : AIDSLINE CAT/9312087
Longitudinal studies of HIV infection in intravenous drug users : methodological issues in natural history research.: Rockville, MD : U.S. Dept. of Health and Human Services, Public Health Service, Alcohol, Drug Abuse, and Mental Health Administration, National Institute on Drug Abuse ; Washington, D.C. : For sale by the Supt. of Docs., U.S. G.P.O., 1991 iv, 153 p. : ill (Research monograph ; 109) Unique Identifier : AIDSLINE CAT/9312127; Hartsock P; Genser SG
[El:SIDA en el derecho penal de la Republica Dominicana.] 1. ed.: Santo Domingo, Republica Dominicana : Editora Corripio, 1991 99 p. : port Unique Identifier : AIDSLINE CAT/9312259; Yepez Suncar LS
Marijuana & AIDS : pot, politics & PWAs in America.: Washington, D.C. : Galen Press, c1991 iii, 183 p. : ill Unique Identifier : AIDSLINE CAT/9312507; Randall RC
World AIDS day features.: [Geneva?] : World Health Organization Global Programme on AIDS, v Unique Identifier : AIDSLINE CAT/9312664
Oklahoma STD/HIV update.: Oklahoma City, Okla. : STD/HIV Division, Epidemiology Service, Oklahoma State Dept. of Health, v. : ill Unique Identifier : AIDSLINE CAT/9312870
Accessions list of the WHO/SPC Information Exchange for the Prevention of AIDS and STD in the Pacific = Recentes adjonctions a la base de donnees Centre OMS/CPS d'echange de documentation pour la prevention du sida et des MST en Oceanie.: in the Pacific [Noumea, New Caledonia] : The Centre, v Unique Identifier : AIDSLINE CAT/9313002
As real as it gets : the life of a hospital at the center of the AIDS epidemic.: New York : Carol Pub. Group, c1992 xv, 255 p Unique Identifier : AIDSLINE CAT/9311476; Pogash C
AIDS impact assessment : modelling and scenario analysis.: Amsterdam ; New York : Elsevier, 1992 xxiii, 319 p. : ill Unique Identifier : AIDSLINE CAT/9311496; Jager JC; Ruitenberg EJ
AIDS/HIV infection : recommendations for health care practices and public policy.: Chicago : American Hospital Association, c1992 17 p Unique Identifier : AIDSLINE CAT/9311499
HIV/AIDS and infection control in dentistry : a self-study course for dental professionals.: [Hollywood, Fla.] : Current Concept Seminars, c1992 45 p Unique Identifier : AIDSLINE CAT/9311656
London International atlas of AIDS.: Oxford, UK ; Cambridge, Mass., USA : Blackwell Publishers, 1992 1 atlas (430 p.) : ill (Blackwell reference) Unique Identifier : AIDSLINE CAT/9311692; Smallman-Raynor M; Cliff AD; Haggett P
Living HIV : a publication of the National Association of People with AIDS. Vol. 1, no. 1 (fall 1992)-: Washington, D.C. : NAPWA, [1992- v. : ill Unique Identifier : AIDSLINE CAT/9312126
Homosexuality and medicine, health, and science.: New York : Garland, 1992 xxi, 335 p. : ill (Studies in homosexuality ; v. 9) Unique Identifier : AIDSLINE CAT/9312453; Dynes WR; Donaldson S
New Jersey Women and AIDS Network news : NJWAN news.: New Brunswick, N.J. : The Network, v Unique Identifier : AIDSLINE CAT/9312540
Tanzania : AIDS assessment and planning study.: Washington, D.C. : World Bank, c1992 xxxviii, 161 p. : ill (A World Bank country study, ISSN 0253-2123) Unique Identifier : AIDSLINE CAT/9312627
Working with women and AIDS : medical, social, and counselling issues.: London ; New York : Tavistock/Routledge, 1992 xiv, 153 p. : ill Unique Identifier : AIDSLINE CAT/9312663; Bury J; Morrison V; McLachlan S
World AIDS day newsletter.: [Geneva, Switzerland] : World Health Organization Global Programme on AIDS, v Unique Identifier : AIDSLINE CAT/9312665
AIDS in Africa : a manual for physicians.: Geneva : World Health Organization, 1992 viii, 125 p. : ill Unique Identifier : AIDSLINE CAT/9312708; Piot P
Caring for a loved one with AIDS : the experiences of families, lovers, and friends.: Seattle : Published for the University of Washington School of Nursing by the University of Washington Press, c1992 vii, 64 p. : ill Unique Identifier : AIDSLINE CAT/9312730; Brown MA; Powell-Cope GM; Utterback LK
Counselling drug users about HIV and AIDS.: Oxford ; Boston : Blackwell Scientific Publications, 1992 xiii, 204 p Unique Identifier : AIDSLINE CAT/9312745; Mulleady G
Report on testing for AIDS.: Toronto, Ont., Canada : The Commission, 1992 xi, 114 p Unique Identifier : AIDSLINE CAT/9313320
The:Source.: Berkeley, CA : AIA National Resource Center, [1992- v. : ports Unique Identifier : AIDSLINE CAT/9313353
Bad blood : the Tuskegee syphilis experiment. New and expanded ed.: New York : Free Press ; Toronto : Maxwell Macmillan Canada ; New York : Maxwell McMillan International, c1993 xv, 297 p. : ill., ports Unique Identifier : AIDSLINE CAT/9311503; Jones JH
[AIDS in Psychiatrie und Neurologie.]: Koln : Deutscher Arzte-Verlag, 1993 268 p. : ill Unique Identifier : AIDSLINE CAT/9311976; Peters UH
Drugs of abuse, immunity, and AIDS.: New York : Plenum Press, c1993 xiv, 286 p. : ill (Advances in experimental medicine and biology ; v. 335) Unique Identifier : AIDSLINE CAT/9312392; Friedman H; Klein TW; Specter S
The:AIDS directory : an essential guide to the 1500 leaders in research, services, policy, advocacy, and funding. 1st ed. (1993)-: Washington, D.C. : Buraff Publications, c1993- v Unique Identifier : AIDSLINE CAT/9313031
Transcending AIDS : nurses and HIV patients in New York City.: Philadelphia : University of Pennsylvania Press, c1994 viii, 199 p (Studies in health, illness, and caregiving) Unique Identifier : AIDSLINE CAT/9312949; McGarrahan P
Fear and AIDS/HIV : empathy and communication.: New York : Delmar Publishers, c1994 xiv, 136 p (Realnursing series) Unique Identifier : AIDSLINE CAT/9313113; Lego S
Questions & answers on AIDS. 2nd ed.: Los Angeles, Calif. : PMIC, c1994 xxiv, 208 p. : Unique Identifier : AIDSLINE CAT/9313313; Frumkin LR; Leonard JM
Man, medicine & microbe : the science of AIDS & long-term survival.: Las Colinas, Tex. : Monument Press, 1994 xi, 179 p. : port (The Politics of AIDS ; v. 6) Unique Identifier : AIDSLINE CAT/9312837; Dickerson NA
HIV infection : a primary care approach. 2nd ed.: Waltham, MA : Pub. Division of the Massachusetts Medical Society, c1994 64 p Unique Identifier : AIDSLINE CAT/9312460; Hecht FM; Soloway B; Cotton DJ; Friedland GH
American cancer society textbook of clinical oncology.: American Cancer Society Textbook of Clinical Oncology. Holleb AI, Fink DJ and Murphy GP, eds. Atlanta, GA, American Cancer Society, 717 p., 1991.. Unique Identifier : AIDSLINE ICDB/93690819; Anonymous; No affiliation given; In the time since publication of this text s predecessor (Clinical Oncology: A Multidisciplinary Approach), the body of knowledge relative to cancer has grown so dramatically that this new, more comprehensive text for medical students and physicians involved in oncology was created to address not only the pathology, e
Pathogenesis of avian nephroblastoma induced by MAV-2(O).: Diss Abstr Int [B]; 52(9):4582 1992. Unique Identifier : AIDSLINE ICDB/93682290; Aidarous HM; Colorado State Univ.; Inoculation of B14 strain embryos at 10 days of incubation with the subgroup B myeloblastosis associated virus, MAV-2(O), results in a massive nephroblastoma by 12 wk of age. The purpose of this dissertation was to examine the possible factors that modulate tumor cell phenotype in avian nephroblastomas. The origin of
High-dose zidovudine (AZT) in patients with treated myelodysplastic syndromes (MDS), and relapsed or refractory AML: a preliminary report (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A1184 1993. Unique Identifier : AIDSLINE ICDB/93692157; Silverman LR; Roboz J; Demakos EP; Holland JF; Derald H. Ruttenberg Cancer Center, Dept. of Neoplastic Diseases,; Mount Sinai Sch. of Medicine, New York, NY 10029; AZT , a chain terminator of DNA synthesis with myelosuppressive effects in patients (pts) with AIDS, can inhibit the growth and induce the differentiation of HL-60 leukemia cells in vitro (Proc AACR 30:53, 1989). In a feasibility study, AZT was adminis
AIDS-related lymphomas: NCI drug discovery efforts (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A2600 1993. Unique Identifier : AIDSLINE ICDB/93693533; Skehan P; Williamson K; Giavazzi R; Malspeis L; Camalier R; Grever M; NCI-FCRDC, Frederick, MD 21701; B-cell lymphomas are a major cause of death in long-term AIDS survivors. The NCI has established an in vitro subpanel of human lymphoma lines to identify new chemotherapeutic agents with antilymphoma selectivity. Agents referred from the NCI in vitro anticancer drug screen are tested in vitro against 10 human B-cell l
Towards optimal anti-Tac antibody dosing in the presence of antigenemia in adult T-cell leukemia-lymphoma (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A2849 1993. Unique Identifier : AIDSLINE ICDB/93693792; Junghans RP; Goldman CK; Carrasquillo J; Reynolds J; Nelson DL; Waldmann TA; New England Deaconess Hosp., Boston, MA 02215; Circulating antigen may interfere with antibody therapy by binding to antibody and reducing access to cellular targets. Patients with Tac+ leukemias and varying levels of circulating antigen (soluble Tac) were infused with anti-Tac antibody for therapy and imaging (Tac=IL2 receptor-alpha). With high soluble Tac levels
Deoxycytidine kinase and drug resistance in cancer and AIDS (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:565-6 1993. Unique Identifier : AIDSLINE ICDB/93694303; Mitchell BS; Ayscue LH; Dept. of Pharmacology, Univ. of North Carolina, Chapel Hill, NC; 27599; Deoxycytidine kinase (dCK) catalyzes the phosphorylation of 2 -deoxyadenosine, 2 -deoxyguanosine, and 2 -deoxycytidine to their corresponding 2 -deoxynucleoside monophosphates and is also required for the phosphorylation of a variety of clinically useful nucleoside analogs including cytosine arabinoside (araC), 2 ,3 -
Phosphorodithioate oligodeoxynucleotide analogs as inhibitors of HIV-1 reverse transcriptase and viral replication.: Diss Abstr Int [B]; 52(9):4710 1992. Unique Identifier : AIDSLINE ICDB/93682297; Marshall WS; Univ. of Colorado at Boulder; Phosphorodithioate DNA is a nucleic acid analog which contains internucleotide phosphodiester groups having sulfur at the two nonlinking positions. We have synthesized a number of dithioate oligodeoxynucleotide analogs and examined the potential anti-HIV activity of these derivatives. Oligodeoxycytidine analogs exhibi
Fatal seronegative human ehrlichiosis in a patient with human immunodeficiency virus disease.: Abstr Gen Meet Am Soc Microbiol. 1993;93:110 (abstract no. D-87). Unique Identifier : AIDSLINE ASM93/93291786; Paddock C; Suchard D; Hadley WK; Kerschmann R; Grumbach K; Dawson J; Dumler JS; Anderson B; Sims K; Herndier B; San Francisco General Hospital, CA.; The first confirmed case of disease due to Ehrlichia chaffeensis occurring in a patient with human immunodeficiency virus type 1 (HIV-1) is reported. A 42 year-old Arkansas woman with HIV-1 disease (CD4 lymphocyte count = 64 cells per cmm) died of pulmonary hemorrhage approximately 2 weeks following acute onset of a f
Evaluation of the new Baxter MicroScan Automated Probe Analyzer for detection of HIV in clinical samples.: Abstr Gen Meet Am Soc Microbiol. 1993;93:134 (abstract no. D220). Unique Identifier : AIDSLINE ASM93/93291787; Bush C; Sherman D; Donovan R; Peterson R; Godsey J; Henry Ford Hospital, Detroit, MI.; A major limitation in the use of PCR in the clinical laboratory is the detection and quantitation of the amplified product. The limitations to current technology include the use of radioactive labels, labor intensive procedures, long time to results and lack of automation. This study applied the MicroScan Automated Pr
Quantitative polymerase chain reaction for HIV is modulated by primer and target sequence.: Abstr Gen Meet Am Soc Microbiol. 1993;93:134 (abstract no. D-219). Unique Identifier : AIDSLINE ASM93/93291788; Byrne BC; Baltazar MC; Baxter JD; UMDNJ/RWJ Med. Sch., Camden.; PCR provides one measure of proviral load in HIV-infected patients. Results are frequently and conveniently expressed as copy number where the patient sample PCR signal is measured against and interpreted through signals from PCR of standard concentrations of control proviral genomes. Copy number calculations provide
Hepatitis B vaccine acceptance in HIV infected patients.: Abstr Gen Meet Am Soc Microbiol. 1993;93:159 (abstract no. E-94). Unique Identifier : AIDSLINE ASM93/93291789; Cobian L; Mayer C; Villanueva L; Sinnott J; Ganguly R; University of South Florida, Tampa.; Human immunodeficiency virus (HIV) infected patients are at high risk of acquiring hepatitis B virus (HBV) infection and also of developing carrier state. Despite these risks, there exists little information regarding HIV patients knowledge of HBV infection and their acceptance of HBV vaccine. A questionnaire was dev
Antibodies to M. genitalium in patients with AIDS and patients attending sexual transmitted diseases clinics.: Abstr Gen Meet Am Soc Microbiol. 1993;93:165 (abstract no. G-18). Unique Identifier : AIDSLINE ASM93/93291790; Wang R; Grandinetti T; Tully J; Davies C; Wear D; Shih J; Lo SC; Armed Forces Inst. of Pathol., Wash. D.C.; Mycoplasma genitalium is a fastidious Mollicute originally isolated from the urethra of two homosexual men with nongonococcal urethritis. The prevalence of M. genitalium infection in humans is not known due to the difficulties of culture isolation from various clinical specimens. We have studied 1333 serum samples fro
Isolation of Mycoplasma species from bronchoalveolar lavage of HIV and non-HIV patients.: Abstr Gen Meet Am Soc Microbiol. 1993;93:165 (abstract no. G-16). Unique Identifier : AIDSLINE ASM93/93291791; Teel L; Finelli M; Johnson S; Henry M. Jackson Foundation for the Advancement of Military; Medicine, Walter Reed Army Medical Center, Washington, D.C.; From March, 1991 through March, 1992, 94 consecutive bronchoalveolar lavages (BAL) performed for diagnosis of suspected infectious pulmonary disease were cultured for mycoplasma as part of the routine microbiological workup. Polymerase chain reaction (PCR) specific for Mycoplasma fermentans was also performed on 89 of
Seroconversion following Mycoplasma penetrans infection in patients with AIDS.: Abstr Gen Meet Am Soc Microbiol. 1993;93:165 (abstract no. G-17). Unique Identifier : AIDSLINE ASM93/93291792; Wang R; Grandinetti T; Melcher G; Hendrix C; Hayes M; Shih J; Lo SC; Armed Forces Inst. of Pathol., Wash, D.C.; Mycoplasma penetrans, a new species of human mycoplasma isolated from patients with AIDS, has a unique tip-like structure and displays prominent pathobiological properties associated with virulence. All 6 clinical isolates share extensive antigenic similarity and DNA homology. We have studied serial serum samples from
The MCR (mycoplasmal cell reactivity), a new concept in cellular infectivity: application as amplification factor for in vitro diagnosis purpose.: Abstr Gen Meet Am Soc Microbiol. 1993;93:165 (abstract no. G-19). Unique Identifier : AIDSLINE ASM93/93291793; Pautrat G; Regis R; Julia F; Dombrecht S; Escarguel C; Papierok G; International Mycoplasma (Groupe STAGO), ZAC de Signes, France.; Mycoplasma has been implied as cofactor in AIDS (MONTAGNIER and lo Groups). We tested different species of Mycoplasma (M. hominis, U. urealyticum, M. orale, M. salivarium, M. fermentans, M. pirium, M. genitalium, etc) on in vitro cellular permissive systems for infectious agents of urogenital and pulmonary tracts (res
AIDS-associated mycoplasmas and antibiotic susceptibilities.: Abstr Gen Meet Am Soc Microbiol. 1993;93:166 (abstract no. G-21). Unique Identifier : AIDSLINE ASM93/93291794; Poulin SA; Perkins RE; Kundsin RB; Brigham and Women's Hospital, Boston, MA.; Because mycoplasmas may be a cofactor in the progression of HIV infection to AIDS, their susceptibilities to antibiotics need to be understood for appropriate therapy. The mycoplasmas studied were: Mycoplasma penetrans; Mycoplasma fermentans, var. incognitus; two strains of Mycoplasma fermentans isolated from AIDS pat
The effect of antimycobacterial treatment on survival of AIDS patients with disseminated Mycobacterium avium complex infection (DMAC).: Abstr Gen Meet Am Soc Microbiol. 1993;93:174 (abstract no. U-35). Unique Identifier : AIDSLINE ASM93/93291795; Otte J; Rimland D; Ivester K; Atlanta Veterans Affairs Medical Center (AVAMC), GA.; DMAC has become the most common bacterial infection in later stages of AIDS. In order to assess the impact of DMAC, with or without specific therapy, on survival we retrospectively reviewed all patients with AIDS seen at AVAMC between 1981 and 1992. Treatment for DMAC was first used in 1989; since that time treatment
Novel, rapid test system to determine mycobacterial antibiotic susceptibility.: Abstr Gen Meet Am Soc Microbiol. 1993;93:175 (abstract no. U-36). Unique Identifier : AIDSLINE ASM93/93291796; Toneguzzo F; Stottmeier K; Brecher S; One Cell Systems, Inc., Cambridge, MA.; Infection of HIV positive individuals with strains of multi-drug resistant tuberculosis (MDRTB) has emerged as a serious and potentially explosive public health problem. These mycobacterial strains, which are essentially untreatable, pose a major threat to HIV infected individuals, health care workers, and ultimately
Detection of 28 and 65 kDa proteins in Mycobacterium avium-intracellulare complex-infected human macrophages.: Abstr Gen Meet Am Soc Microbiol. 1993;93:180 (abstract no. U-66). Unique Identifier : AIDSLINE ASM93/93291797; Ippoliti F; Fattorini L; Damiani G; Santoro C; Arizzi M; Xiao Y; Orefici G; La Sapienza University, Rome, Italy.; Organisms belonging to Mycobacterium avium-intracellulare complex (MAC) are the most common bacterial pathogens isolated from acquired immunodeficiency syndrome (AIDS)-patients. MAC are usually present within tissue macrophages where they proliferate with little evidence of inflammatory response. To investigate if mem
Suppression of lymphocyte proliferation by Mycobacterium avium complex in HIV infected and normal healthy individuals.: Abstr Gen Meet Am Soc Microbiol. 1993;93:180 (abstract no. U-67). Unique Identifier : AIDSLINE ASM93/93291798; Ghassemi M; Reddy MV; Gangadharam PR; Andersen B; Novak R; University of Illinois, Chicago.; Disseminated Mycobacterium avium complex (MAC) infection is the common opportunistic infection in AIDS patients. MAC forms several isogenic colonial variants, smooth transparent (ST) colonial variant, most frequently isolated from AIDS patients, smooth opaque (SO) and rough opaque (RO) variants, commonly found in the
T cell mitogenesis-inhibitory activity of phospholipid fraction of M. intracellulare.: Abstr Gen Meet Am Soc Microbiol. 1993;93:180 (abstract no. U-68). Unique Identifier : AIDSLINE ASM93/93291799; Tomioka H; Saito H; Shimane Medical University, Izumo, Japan.; Previously, phospholipid (PL) and polar mycoside fractions of M. avium complex (MAC) were found to have immunosuppressive activity against ConA-induced T cell mitogenesis. In this study, we investigated the immunosuppressive mechanism of action of the PL fraction, which was prepared by serial extractions with acetone,
Intestinal macrophages (MO) can be activated to kill intracellular Mycobacterium avium complex (MAC) but have differentiated ability to produce cytokines.: Abstr Gen Meet Am Soc Microbiol. 1993;93:181 (abstract no. U-69). Unique Identifier : AIDSLINE ASM93/93291800; Hsu N; Young L; Bermudez LE; Kuzell Institute, San Francisco, CA.; Current evidence suggest that the gut is the main portal of entry of MAC infection in AIDS patients. Bacterial invasion of the intestinal mucosa presumably occurs throughout the M cells where they come in contact with immuno-competent cells such as MO, T and B lymphocytes. As mucosal MO are the first line of defense,
Isolation and characterization of Mycobacterium avium isolates from African water samples.: Abstr Gen Meet Am Soc Microbiol. 1993;93:182 (abstract no. U-79). Unique Identifier : AIDSLINE ASM93/93291801; Eaton T; Falkinham JO; Von Reyn CF; Waddell R; Gilks CF; Brindle RJ; VPI&SU, Blacksburg 24061-0406.; Mycobacterium avium and Mycobacterium intracellulare (M. avium complex, MAC) are opportunistic human pathogens whose source of infection is the environment. Though disseminated MAC infection occurs in as many as 25% of United States AIDS patients, the prevalence of disseminated MAC inf
Mycobacterium tuberculosis bacteremia at Cook County Hospital: a 30-month experience.: Abstr Gen Meet Am Soc Microbiol. 1993;93:183 (abstract no. U-82). Unique Identifier : AIDSLINE ASM93/93291802; Fernandez J; Pulvirenti J; Wurtz R; Panovic S; Kocka F; Cook County Hospital-Rush Medical College, Chicago, IL.; Patients with Mycobacterium tuberculosis (MTb) bacteremia are not well described. Over a 30-month period, Cook County Hospital had 497 patients with documented MTb, 68 of these had mycobacterial blood cultures done, 14 were positive. MTb constituted 21% of all mycobacterial bacteremias. All 14 were HIV-positive with a
Pathologic findings in disseminated Mycobacterium genavense infection.: Abstr Gen Meet Am Soc Microbiol. 1993;93:185 (abstract no. U-94). Unique Identifier : AIDSLINE ASM93/93291803; Wilson M; Seilstad K; Bessesen M; Cohn D; Winter S; Department of Health & Hospitals, Denver, CO.; M. genavense is a newly-described mycobacterium that causes opportunistic infections in patients with AIDS. Of 4 patients with M. genavense infection who have been evaluated and treated at our institution, pathological material from 2 has been available for examination. Patient #1, a 29 year-old male, underwent biopsy
Physical mapping of nine genes to the chromosome of rat Pneumocystis carinii.: Abstr Gen Meet Am Soc Microbiol. 1993;93:194 (abstract no. H-24). Unique Identifier : AIDSLINE ASM93/93291804; Dykstra CC; Fletcher LD; Berger LC; Tidwell RR; Dept. of Pathology, Univ. of North Carolina, Chapel Hill.; Despite being an important AIDS-related pathogen, little is known about the genome of Pneumocystis carinii. The identification of essential housekeeping genes and comparison of the genes to other organisms will aid in the phylogenetic determination of P. carinii as well as identify potential therapeutic targets for im
Cutaneous Protothecosis in a patient with AIDS.: Abstr Gen Meet Am Soc Microbiol. 1993;93:255 (abstract no. I-86). Unique Identifier : AIDSLINE ASM93/93291805; Koestenblatt E; Woolrich A; Don P; Szaniawski W; Metropolitan Hospital Center, New York Medical College, Valhalla.; Cutaneous Protothecosis an uncommon infection caused by achlorophyllic algae is seen primarily in immunosuppressed patients. Diagnosis may be quite challenging due to the rarity of the infection as well as the non-specific and variable clinical picture. Our patient, a 33 year old Hispanic female with AIDS developed a
Factors involved in microsporidian spore polar filament (infection apparatus) extrusion.: Abstr Gen Meet Am Soc Microbiol. 1993;93:27 (abstract no. B-6). Unique Identifier : AIDSLINE ASM93/93291806; He Q; Leitch GJ; Visvesvara GS; Wallace S; Morehouse Sch. Med., Atlanta, GA.; Microsporidia are obligate intracellular protozoan parasites. An in vitro polar filament extrusion assay was developed using spores from a strain of Encephalitozoon hellem isolated from an AIDS patient and cultured in a monkey kidney cell line. Incubation in a medium resembling extracellular fluid resulted in polar fi
Restriction endonuclease patterns of non-serotypable adenoviruses recovered from AIDS patients.: Abstr Gen Meet Am Soc Microbiol. 1993;93:429 (abstract no. S-13). Unique Identifier : AIDSLINE ASM93/93291807; Chegas PM; Pierce CS; Riepenhoff-Talty MR; Amsterdam D; Children's Hospital of Buffalo, N.Y.; Over a two year period, 25 adenovirus (AV) isolates were recovered from fecal samples of 14 HIV-seropositive males. Specimens were inoculated into A-549 cells. Virus replication as evidenced by cytopathic effect was confirmed by specific AV immunofluorescent staining. Using conventional serum neutralization (SN) three
Cytotoxicity to HIV-infected cells of a Shiga toxin-CD4 fusion protein.: Abstr Gen Meet Am Soc Microbiol. 1993;93:43 (abstract no. B-96). Unique Identifier : AIDSLINE ASM93/93291808; al-Jaufy AY; Haddad JE; Jackson MP; Wayne State Univ. Medical School, Detroit, MI.; Shiga toxin (STX), a cytotoxin produced by Shigella dysenteriae 1, is targeted to a specific glycolipid receptor on susceptible cells by its B subunit. STX enters the cell by receptor mediated endocytosis and the enzymatic (A) subunit is translocated to the ribosomes where it inhibits protein synthesis. The STX A poly
Proviral burden quantitation in peripheral blood mononuclear cells from HIV-1 infected patients by the method of PCR-enzyme-linked-capture-hydroxyapatite-assay (ELCHA) as subrogated marker for AIDS prediction.: Abstr Gen Meet Am Soc Microbiol. 1993;93:433 (abstract no. T-9). Unique Identifier : AIDSLINE ASM93/93291809; Garcia-Cabrera L; Ruiz-Palacios G; Instituto Nacional de la Nutricion Salvador Zubiran, Mexico,; D.F.; CD4+ lymphocytes are the only recognized standard marker to measure the level of immunodeficiency and progression to AIDS in HIV-1 infected patients. It is important to find other markers for AIDS prediction. In this study we developed an enzymatic-colorimetric assay to quantify proviral burden in peripheral blood mon
Quantitation of HIV-1 RNA in plasma using a signal amplification branched DNA (bDNA) assay.: Abstr Gen Meet Am Soc Microbiol. 1993;93:433 (abstract no. T-10). Unique Identifier : AIDSLINE ASM93/93291810; Pachl C; Elbeik T; Saxer M; Kern D; Stempien M; Fong SJ; Sheridan P; Yeghiazarian T; Neuwald P; Urdea M; et al; Chiron Corp., Emeryville, CA.; The level of HIV-1 RNA in plasma has been quantitated using a nucleic acid hybridization assay based on signal amplification branched DNA (bDNA) technology. The RNA target is captured onto a microwell surface, detected via bDNA amplifier molecules and alkaline phosphatase labeled probes, and signal is generated using
p24 antigenemia in HIV-infected pediatric patients: comparison with virus culture.: Abstr Gen Meet Am Soc Microbiol. 1993;93:434 (abstract no. T-14). Unique Identifier : AIDSLINE ASM93/93291811; Paul M; Pahwa S; North Shore Univ. Hosp.-Cornell Univ. Med. Col., Manhasset, N.Y.; Sera (52) from 28 HIV-infected children (CDC class, P2), aged, 0.8-106 months, were examined for HIV p24 antigen (Coulter), without (Cont) and with, acid hydrolysis (AH) treatment. Virus isolation was attempted in corresponding plasma and PBMC of the same patients. Results show: 1. No difference in positivity rates fo
An in-vivo protease inhibitor screening assay using a non-infectious HIV-1 proviral clone.: Abstr Gen Meet Am Soc Microbiol. 1993;93:434 (abstract no. T-16). Unique Identifier : AIDSLINE ASM93/93291812; Heldsinger AA; Antonucci TK; Department of Infectious Diseases, Parke-Davis Pharmaceutical; Research, Division of Warner Lambert Company, Ann Arbor, MI; 48105.; We developed an in-vivo assay to screen for protease inhibitors using a non-infectious HIV-1 proviral clone (X19) with a deletion in the envelope gene. COS 7 cells were transfected by the calcium phosphate technique with 10 micrograms of X19 DNA cloned into the plas
Detecting HIV-1 seroconverters by a sensitive peptide EIA.: Abstr Gen Meet Am Soc Microbiol. 1993;93:434 (abstract no. T-13). Unique Identifier : AIDSLINE ASM93/93291813; Lee-Thomas S; Pau CP; Schochetman G; George JR; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta.; Sixteen overlapping synthetic peptides from the immunodominant region of HIV-1 gp41 (amino acids 581-623) were evaluated in an enzyme immunoassay (EIA) to detect early seroconversion of HIV-1. In addition, two 14 amino-acid peptides, one corresponding to the principle neutralizing domain (V3 region) of HIV-1 gp120, (a
Human immunodeficiency virus culture positivity as related to participation in clinical trials.: Abstr Gen Meet Am Soc Microbiol. 1993;93:434 (abstract no. T-11). Unique Identifier : AIDSLINE ASM93/93291814; Kuk R; Gaur S; Frenkel LD; John JF; Robert Wood Johnson Medical School, New Brunswick, N.J.; Viremia with HIV can provide insights into the progression of HIV infection. Our HIV culture laboratory supports an AIDS Clinical Trials Unit (ACTU) but also processes other non-ACTU samples. We questioned if the rates of positive cultures differed between these two groups. Cultures were performed using 6 x 10(6) pati
HIV-1 detection by PCR and alkaline phosphatase directly labeled DNA probes.: Abstr Gen Meet Am Soc Microbiol. 1993;93:434 (abstract no. T-12). Unique Identifier : AIDSLINE ASM93/93291815; Castro M; Bishr M; Tang K; Vela R; University of North Texas, Denton.; A DNA amplification procedure using a heat stable DNA Polymerase and the polymerase chain reaction is described for the detection of HIV-1. A set of primers was designed to obtain a 500 b.p. amplification product from the gag region of a plasmid containing an inactivated version of HIV-1. Using this set of primers in
Quantitation of HIV-1 RNA by PCR with Tth DNA polymerase.: Abstr Gen Meet Am Soc Microbiol. 1993;93:434 (abstract no. T-15). Unique Identifier : AIDSLINE ASM93/93291816; Mulder J; McKinney N; Christopherson C; Sninsky J; Kwok S; Roche Molecular Systems, Alameda, California.; The development of a quantitative assay for particulate viral RNA involves four critical elements: sample preparation, efficient and reproducible amplification of RNA, internal control, and quantitative detection. A single tube, single enzyme system has been developed for quantitation of HIV RNA in plasma or sera by P
Anti-CD4 antibodies are associated with a specific decrease in CD4-positive lymphocytes in HIV-1 seroconverters. The Multicenter AIDS Cohort Study (MACS).: Abstr Gen Meet Am Soc Microbiol. 1993;93:435 (abstract no. T-22). Unique Identifier : AIDSLINE ASM93/93291817; Keay S; Wecksler W; Wasserman SS; Department of Veterans Affairs Medical Center, Baltimore, MD.; We previously showed that anti-CD4 antibodies may be present in up to 85% of persons at the time of HIV-1 seroconversion, the timing of which response suggests that these anti-CD4 antibodies are generated as anti-idiotype antibodies against anti-gp 120/160 antibodies made in response to HIV-1 infection. Such anti-idio
Chemiluminescent detection of PCR amplified HIV-1 DNA from peripheral blood mononuclear cells of migrant farm workers.: Abstr Gen Meet Am Soc Microbiol. 1993;93:435 (abstract no. T-17). Unique Identifier : AIDSLINE ASM93/93291818; Bankowski MJ; Schulte J; Frees N; Horton P; Landay A; Staes B; Shuburg R; Caueffield D; Knapp R; Glinski B; et al; Diagnostic Services, Inc., Naples Community Hospital, FL.; A recent study of migrant farm workers in Florida showed a high seropositivity rate for both HIV-1 (5%) and syphilis (8%) [CDC. MMWR 1992;41:723-725]. We selected a subgroup of 35 from these 310 participants to further investigate with both HIV-1 co-culture and the polymerase chain reaction (PCR). Our patient group co
Evaluation of HIV-1 perinatal infection by a modified HIV-1 IgA immunoblot assay.: Abstr Gen Meet Am Soc Microbiol. 1993;93:435 (abstract no. T-20). Unique Identifier : AIDSLINE ASM93/93291819; Norman GL; Gross M; Yee J; Carlson J; Microbiology Reference Laboratory, Cypress, CA.; Approximately 13-45% of children born to HIV-infected mothers are expected to become infected with HIV-1. Serological diagnosis of infection in infants is confounded by the presence of passively acquired maternal IgG. Recent reports have documented the efficacy of detecting IgA antibodies to HIV-1 for the early diagno
Isotype and specificity of the antibody response to HIV in Puerto Rico.: Abstr Gen Meet Am Soc Microbiol. 1993;93:435 (abstract no. T-19). Unique Identifier : AIDSLINE ASM93/93291820; Hernandez M; Montealegre F; Diaz AM; Dept. of Microbiology and Medical Zoology, Univ. of P.R.; In this study, we have investigated by Western blot analysis the isotypic profile of the antibody response to HIV structural proteins (env, gag, and pol) for IgG subclasses. The study involves 100 HIV-1 positive Puerto Rican patients at various stages of infection that visited the Centro Latinoamericano de Enfermedade
Kinetics of HIV p24 decrease after initiation of ZDV therapy assessed by immune complex dissociation and non-immune complex dissociation assays.: Abstr Gen Meet Am Soc Microbiol. 1993;93:435 (abstract no. T-21). Unique Identifier : AIDSLINE ASM93/93291821; Donovan RM; Smereck SM; Bush CE; Baxa DM; Griffin N; Markowitz NP; Saravolatz LD; Department of Infectious Diseases, Henry Ford Hospital, Detroit,; Michigan.; HIV p24 antigenemia is a surrogate marker for assessing therapeutic efficacy in clinical trials and monitoring patients on antiretroviral therapy. Recently, measurement of HIV p24 antigenemia after dissociation of immune complexes (IC) has been shown to increase the sensitivity of detection of p24 antigenemia. This st
The use of PCR and a non-radioactive microwell hybridization assay to screen blood from potential corneal donors for the presence of HIV-1.: Abstr Gen Meet Am Soc Microbiol. 1993;93:435 (abstract no. T-18). Unique Identifier : AIDSLINE ASM93/93291822; Kinard SJ; Wang H; Pepose J; Connell S; Batchelor J; Locklear J; McCreedy B; Danagan E; Spadoro JP; Roche Molecular Systems, Branchburg, NJ.; In recent years, it has become increasingly important to assure that transplanted organs and tissues are free of any contaminating agents that may result in disease and/or death to the recipient. Towards that effort, we are testing the efficacy of using PCR coupled with a non-radioactive microwell assay for the detect
Activation of human polyoma virus early gene promoters by HIV-1 transactivator Tat.: Abstr Gen Meet Am Soc Microbiol. 1993;93:436 (abstract no. T-28). Unique Identifier : AIDSLINE ASM93/93291823; Mondal D; Zhang D; Prakash O; Alton Ochsner Medical Foundation, New Orleans, LA.; Progressive multifocal leukoencephalopathy (PML) occurs in AIDS patients at a much higher frequency than in other immunosuppressive disorders. In view of the growing body of evidence that Tat is not only essential for the HIV infectious cycle, but may also be directly involved in many HIV-1 infection-associated compli
Assays to detect AIDS receptor antagonists, compounds that inhibit the binding of the HIV-1 surface glycoprotein, gp120, to the CD4 receptor on human T-lymphocytes.: Abstr Gen Meet Am Soc Microbiol. 1993;93:436 (abstract no. T-23). Unique Identifier : AIDSLINE ASM93/93291824; Tait-Kamradt A; Petitpas J; Clancy J; McGuirk P; Subashi T; Watts P; Wondrack L; Pfizer Central Research, Groton, CT.; The AIDS virus, HIV-1, infects human helper T-lymphocytes via an interaction between gp120, the viral coat protein, and the T-cell receptor, CD4. Disruption of this interaction blocks infection in vitro. Microtiter-based immunoassays developed to measure gp120/CD4 binding were used to screen a variety of compounds for
Clinical characteristics and outcome of HIV patients with Pneumocystis carinii pneumonia at the San Juan VAMC.: Abstr Gen Meet Am Soc Microbiol. 1993;93:436 (abstract no. T-26). Unique Identifier : AIDSLINE ASM93/93291825; Ruiz H; Curet J; Ramirez Ronda C; Rivera Vazquez CR; Laureano A; Ojeda A; San Juan VAMC, Department of Medicine, Puerto Rico.; Although advances in detection and management, Pneumocystis carinii pneumonia (PCP) continue to be a serious problem to HIV infected patients (Pts). The typical pattern of clinical presentation has become increasingly varied with the use of antiviral therapy and anti-Pneumocystis prophylaxis agents. Regardless of pres
Cytomegalovirus polyradiculopathy syndrome in HIV infected patients.: Abstr Gen Meet Am Soc Microbiol. 1993;93:436 (abstract no. T-27). Unique Identifier : AIDSLINE ASM93/93291826; Meier P; Blatt S; Wilford Hall Medical Center, San Antonio, Texas.; Cytomegalovirus polyradiculopathy is a rare neurologic syndrome which is reported to occur in less than 1% of AIDS patients. We describe four patients with CMV polyradiculopathy from a cohort of 216 AIDS patients followed in the USAF HIV Natural History Study (i
In vitro anti HIV-1 activity of alkaline autooxidized catechinic acid (AOCA).: Abstr Gen Meet Am Soc Microbiol. 1993;93:436 (abstract no. T-24). Unique Identifier : AIDSLINE ASM93/93291827; Ferrea G; Ranieri E; Fioredda F; Corradino P; Sampietro F; Astegiano G; Cruciani M; Romussi G; Bassetti D; University of Genoa-Italy.; Certain natural polyphenols possess an antiviral activity. Catechin and catechinic acid belong to these chemical compounds. In this study we evaluated the antiviral activity of AOCA, derived from catechinic acid alkaline autooxidation, on HIV-1 cell cultures. HIV 1 was obtained from culture supernatant of H9/HTLVIIIB
Sequential quantitative analysis of viral activity in HIV-1 infected patients.: Abstr Gen Meet Am Soc Microbiol. 1993;93:436 (abstract no. T-25). Unique Identifier : AIDSLINE ASM93/93291828; Bagnarelli P; Menzo S; Valenza A; Clementi M; Institute of Microbiology, University of Ancona, Italy.; We have developed and used a competitive polymerase chain reaction (cPCR) to examine the level of HIV-1 activity in symptomatic and symptomless infected patients. Using this molecular approach quantitative data on (i) HIV-1 viremia levels (HIV-1 genome molecules in plasma samples), (ii) specific viral transcripts (tra
Discovery of HIV-1 protease inhibitors from natural products and synthetic compounds.: Abstr Gen Meet Am Soc Microbiol. 1993;93:437 (abstract no. T-29). Unique Identifier : AIDSLINE ASM93/93291829; Tomich P; Lynn J; Horng M; Seest E; Dolak L; Bohanon M; Upjohn Company, Kalamazoo, MI.; HIV, the presumed etiological agent that induces AIDS, has elicited a massive effort to control and hopefully cure this disease. To that end, we have instituted a procedure to discover potential therapeutic agents targeted against the viral encoded protease. The virus demands functional utility of this enzyme at sever
Effect of TAT and protease inhibitors on HIV-1 activation in OM-10.1 cells.: Abstr Gen Meet Am Soc Microbiol. 1993;93:437 (abstract no. T-32). Unique Identifier : AIDSLINE ASM93/93291830; Feorino PM; Butera ST; Folks TM; Schinazi RF; Emory University, Atlanta, GA.; OM-10.1 cells consistently remain CD4+ and clonally harbor a single provirus copy while constitutively expressing very low levels of HIV-1. After treatment with TNF-alpha, there is a marked down modulation of CD4+ cells and an extensive increase of HIV expression within 24 hr. Our group has used the OM-10.1 cells to e
Evaluation of Murex rapid microfiltration assay for HIV-1 antibodies in serum.: Abstr Gen Meet Am Soc Microbiol. 1993;93:437 (abstract no. T-34). Unique Identifier : AIDSLINE ASM93/93291831; Arens M; Park C; Dept Pediatrics, Washington Univ Med Sch, St. Louis, MO 63110.; The Murex Single Use Diagnostic System (SUDSR) HIV-1 Test is a 10-min enzyme immunoassay for the detection of HIV-1 antibodies. The test employs affinity-purified p24 antigen and a gp41 transmembrane synthetic peptide. We evaluated the SUDSR HIV-1 test (Murex) and compared it to Organon Teknika ELISA and EpitopeR west
Expression of HIV-1 genes placed under the control of the lac promoter in pUC18 tested in various potential bacterial carrier strains.: Abstr Gen Meet Am Soc Microbiol. 1993;93:437 (abstract no. T-30). Unique Identifier : AIDSLINE ASM93/93291832; Branstrom A; Benson J; Aggarwal A; Franchini G; Sadoff J; Warren R; Walter Reed Army Inst. of Res., Washington, D.C.; The sequence for HIV-1 MN was used to make primers to PCR amplify portions of the genes encoding for ENV, GAG, POL, NEF and VIF. These regions were chosen since they contain epitopes involved in the CTL response, which may prove advantageous for the development of a vaccine. Primers were designed containing BamHI and
High-dose recombinant soluble CD4 (rsCD4) in patients with HIV-1 infection.: Abstr Gen Meet Am Soc Microbiol. 1993;93:437 (abstract no. T-33). Unique Identifier : AIDSLINE ASM93/93291833; Sachs M; Fong KL; Blanchard L; Wikler M; Jefferson Med. Coll., Phila., PA.; A study of rsCD4, administered in a maximal dosage of 30 mg per day, provided suggestive evidence of this drug s antiretroviral activity in humans. Nonetheless, this dosage achieved maximum serum concentrations (Cmax) of only 50 to 300 ng/ml. Thus, we treated patients with a dosage of 5 mg/kg per day of rsCD4 administ
HTLV-II isolates from Italian IVDUs belong to IIb subtype.: Abstr Gen Meet Am Soc Microbiol. 1993;93:437 (abstract no. T-31). Unique Identifier : AIDSLINE ASM93/93291834; Zella D; Salemi M; Achilli G; Cattaneo E; Landini V; Casoli C; Bertazzoni U; IGBE/CNR, Pavia, Italy.; HTLV-II was isolated from two Italian intravenous drug users (IVDUs) coinfected with HIV-1. The new isolates, HTLV-II Gu and Va, were characterized by sequence analysis of LTR and regions of gag, env and X genes. From the sequence of 1988 nucleotides examined, a variability of 1.6% was found between new isolates and o
Detection of BIV provirus in bovine cells by polymerase chain reaction.: Abstr Gen Meet Am Soc Microbiol. 1993;93:438 (abstract no. T-39). Unique Identifier : AIDSLINE ASM93/93291835; Nash JW; Hanson LA; St. Cyr-Coats K; Mississippi State University.; Bovine immunodeficiency-like virus (BIV), a lentivirus related to HIV, causes a syndrome in cattle which is similar to AIDS. Although a seroprevalence greater than 50% was demonstrated in Mississippi dairy herds, the mode of BIV transmission is undefined. The purpose of this study was to develop a PCR probe to amplify
Genetic variability in the HIV-1 principal neutralizing domain from North American and African isolates.: Abstr Gen Meet Am Soc Microbiol. 1993;93:443 (abstract no. T-66). Unique Identifier : AIDSLINE ASM93/93291836; Massey J; Downes F; Johnson D; Martin R; Gath E; Booth C; Shaw M; Maassab H; Mich. Dept. Publ. Hlth., Lansing.; HIV-1 exhibits extensive genetic variability, particularly in the envelope gene (env). The third hypervariable (V3) region of env contains the primary neutralizing domain (PND). Mutants capable of avoiding the hosts immune response may arise from nucleic acid changes in the PND. Whole blood specimens were received fro
Structure-function analysis of the HIV-1 envelope V3 loop tropism determinant.: Abstr Gen Meet Am Soc Microbiol. 1993;93:443 (abstract no. T-67). Unique Identifier : AIDSLINE ASM93/93291837; Ratner L; Carrillo A; Ebenbichler C; Gu R; Washington University, St. Louis, Mo.; The V3 loop of the HIV-1 gp120 envelope protein is a critical determinant of macrophage-tropism. Using full-length HIV clones, substitution of a macrophage-tropic V3 loop into a T cell line tropic isolate abolished T cell line replication. Although the V3 loop was insufficient for T cell line tropism in a macrophage-t
A human monoclonal antibody to a cryptic gp41 epitope on HIV-1 infected cells.: Abstr Gen Meet Am Soc Microbiol. 1993;93:444 (abstract no. T-70). Unique Identifier : AIDSLINE ASM93/93291838; Myers R; Meiller T; Falkler W Jr; Patel J; Joseph J; MD Department of Health Laboratories, Baltimore.; The development of HIV-1 human monoclonal antibodies (huMAb) has provided valuable insights into the immune response to HIV-1 infections. We have developed a IgG1 (lambda) HIV-1 gp41 huMAb (MD-1) which exclusively reacts with oligomeric forms of gp41 on immunoblots. The binding of the huMAb has been localized to the N
HIV-1 replication in non-dividing cells.: Abstr Gen Meet Am Soc Microbiol. 1993;93:444 (abstract no. T-73). Unique Identifier : AIDSLINE ASM93/93291839; Dempsey M; Haggerty S; Gulizia J; Bukrinsky M; Stevenson M; University of Nebraska Medical Center, Omaha.; Completion of the retroviral life cycle is dependent upon integration of viral DNA with the host cell genome and establishment of the provirus. Following reverse transcription and prior to integration, the viral RNA remains associated with viral cDNA and integrase in a high molecular weight pre-integration complex. Ta
Inhibition of HIV-1 infection and syncytia formation by synthetic peptides from the V3 loop in gp120: potential for AIDS therapy.: Abstr Gen Meet Am Soc Microbiol. 1993;93:444 (abstract no. T-68). Unique Identifier : AIDSLINE ASM93/93291840; Nehete P; Arlinghaus R; Sastry J; University of Texas M.D. Anderson Cancer Center, Houston.; Several reports described that the V3 loop in the envelope protein gp120 of human immunodeficiency virus type 1 (HIV-1) not only represents an immunodominant region but also is important for virus infection. We observed that synthetic peptides representing V3 loop regions from 11 different HIV-1 strains when used at n
Mutations within the leucine zipper of the transmembrane protein (gp41) of HIV interfere with wild-type mediated membrane fusion.: Abstr Gen Meet Am Soc Microbiol. 1993;93:444 (abstract no. T-71). Unique Identifier : AIDSLINE ASM93/93291841; Seaman WT; Fenger TW; Marshall Univ. Sch. of Med., Huntington, W.V. 25755-9330.; Assembly of the HIV envelope protein into oligomers is mediated by interactions between monomers of the transmembrane protein, gp41. We are interested in determining the significance of oligomerization in the production of functional Env protein. An expression plasmid was constructed containing the env coding sequence
Potential role of a calmodulin-binding segment of HIV-1 TM protein in the uncoupling of signal transduction in HIV-infected cells.: Abstr Gen Meet Am Soc Microbiol. 1993;93:444 (abstract no. T-72). Unique Identifier : AIDSLINE ASM93/93291842; Miller MA; Mietzner TA; Cloyd MW; Montelaro RC; University of Pittsburgh School of Medicine, PA.; It has been well documented that signal transduction within HIV-infected lymphocytes is significantly perturbed resulting in the inability of these cells to become activated and proliferate. We have identified a 28-residue segment localized to the extreme carboxyl terminus of HIV-1 transmembrane (TM) protein which has
Sequential analysis of the V3 loop in HIV-1 from a pediatric population.: Abstr Gen Meet Am Soc Microbiol. 1993;93:444 (abstract no. T-69). Unique Identifier : AIDSLINE ASM93/93291843; Massey J; Downes F; Johnson D; Martin R; Gath E; Booth C; Shaw M; Maassab H; Mich. Dept. Publ. Hlth., Lansing.; Transmission of HIV-1 from mother to infant has become the primary route for pediatric infection. Genetic characteristics of HIV-1 may influence transmission efficiency, while immune modulation may influence the rate of disease progression. HIV-1 gag, LTR and env regions were amplified by the polymerase chain reaction
Characterization of feline immunodeficiency virus mutants selected with ddI alone and in combination with AZT.: Abstr Gen Meet Am Soc Microbiol. 1993;93:445 (abstract no. T-76). Unique Identifier : AIDSLINE ASM93/93291844; Gobert JM; Remington KM; Zhu YQ; North TW; University of Montana, Missoula.; Mutants of feline immunodeficiency virus (FIV) were selected in vitro by passage in the presence of 2 ,3 -dideoxyinosine (ddI) or a combination of ddI and 3 -azido-3 -deoxythymidine ( AZT ). Mutants were selected from both the wild-type, Petaluma strain
Characterization of AZT-resistant mutants of feline immunodeficiency virus selected from a molecular clone.: Abstr Gen Meet Am Soc Microbiol. 1993;93:445 (abstract no. T-77). Unique Identifier : AIDSLINE ASM93/93291845; Remington KM; North TW; Phillips TR; Univ. of Montana, Missoula.; The nucleoside analog, 3 -azido-3 -deoxythymidine ( AZT ), has been widely used for treatment of patients with the acquired immune deficiency syndrome (AIDS). Recently, human immunodeficiency virus (HIV) that is resistant to AZT has been isolated from A
Met184 mutation on HIV-1 RT confers resistance to the oxathiolane nucleoside analogues (-)-BCH-189 and (-)-FTC.: Abstr Gen Meet Am Soc Microbiol. 1993;93:445 (abstract no. T-75). Unique Identifier : AIDSLINE ASM93/93291846; Schinazi RF; Lloyd RM Jr; Nguyen MH; Cannon D; Ilksoy N; Chu CK; Liotta DC; Mellors JW; VA Med. Ctr./Emory Univ, Decatur, GA 30033.; (-)-2 ,3 -Dideoxy-5-fluoro-3 -thiacytidine [(-)-FTC] and (-)-2 ,3 -dideoxy-3 -thiacytidine [(-)-BCH-189] selectively inhibit HIV-1, HIV-2, and HBV in vitro. The potential for HIV resistance to these compounds was evaluated by serial passage of the virus in primary human lymphocytes and MT-2 cells in the presence of in
Modulations in cellular factor availability can synergistically alter the rate of Tat-mediated transactivation of HIV.: Abstr Gen Meet Am Soc Microbiol. 1993;93:445 (abstract no. T-74). Unique Identifier : AIDSLINE ASM93/93291847; Mondal D; Prakash O; Alton Ochsner Medical Foundation, New Orleans, LA.; HIV-1 Tat requires both the promoter elements [Sp1 and TATA] and the Tar region, for transactivation of HIV-1 LTR. In addition to Tat a number of cellular proteins are also essential for transactivation. Since, these cellular factors play a key role in the transactivation it has been our goal to investigate the level
Clinical utility of HIV-1 p-24 antigen assays; an evaluation.: Abstr Gen Meet Am Soc Microbiol. 1993;93:451 (abstract no. C-32). Unique Identifier : AIDSLINE ASM93/93291848; Ndimbie OK; Riddle P; Central Blood Bank, Pittsburgh, PA.; HIV-1 antigen (HIV-1 Ag) testing can facilitate HIV diagnoses in the window period, and in the presence of passive antibody. Neonates with seropositive mothers, tissue donors, persons inadvertently exposed to potentially infectious body fluids, and those with indeterminate (IND) HIV-1 Western Blot (WB) can benefit fro
Evaluation of an automated, contained nonradioisotopic polymerase chain reaction-based assay for detection of human immunodeficiency virus (HIV) type 1 and 2. Nucleic Acid Diagnostic Program members.: Abstr Gen Meet Am Soc Microbiol. 1993;93:451 (abstract no. C-31). Unique Identifier : AIDSLINE ASM93/93291849; Atwood S; Ekeze T; Cummins T; Clinical Diagnostics Division, Eastman Kodak Company, Rochester,; NY 14650-2117.; The polymerase chain reaction (PCR) has revolutionized the direct detection of HIV due to its exquisite sensitivity. However, rigorous protocols such as separate laboratories and designated personnel are currently required to prevent false positives due to amplified sequence contamination. Eastman Kodak Company Clinic
Improved detection and quantitation of HIV-1 antigen after dissociation of immune complexes.: Abstr Gen Meet Am Soc Microbiol. 1993;93:451 (abstract no. C-33). Unique Identifier : AIDSLINE ASM93/93291850; Starkey C; Yen-Lieberman B; Proffitt MR; Cleveland Clinic Foundation, Ohio.; The frequency with which current tests for HIV-1 p24 antigen can detect the antigen in serum of infected individuals is low. This has been attributed, in part, to the presence in the blood of HIV-1 antibodies that complex with antigen and render it undetectable. Based on quantity of specimen available, we selected 40
Microbiology, epidemiology, and prognostic significance of bacteremia (B) and fungemia (F) in HIV-infected (HIV+) and HIV-uninfected (HIV-) patients (pts).: Abstr Gen Meet Am Soc Microbiol. 1993;93:487 (abstract no. C-234). Unique Identifier : AIDSLINE ASM93/93291851; Quartey S; Towns M; Weinstein MP; Mirrett S; Reimer LG; Reller LB; Robert Wood Johnson Medical School, New Brunswick, NJ.; As part of a prospective evaluation of 1000 patients, we are comparing B and F in HIV+ and HIV- pts. Of 555 episodes analyzed to date, 54 (51 unimicrobial, 3 polymicrobial) were in HIV+ pts. The most common isolates in HIV+ pts were S. aureus (15), P. aeruginosa (10), M. avium complex (10), and C. neoformans (6); wher
Epidemiology and natural history of cytomegalovirus (CMV) infection in HIV-1 seropositive women.: Abstr Gen Meet Am Soc Microbiol. 1993;93:494 (abstract no. C-273). Unique Identifier : AIDSLINE ASM93/93291852; Clarke L; Duerr A; Daidone B; Rizvi S; Sierra M; Ehrlich I; Dehovitz J; Minkoff H; SUNY Health Science Ctr, Brooklyn.; CMV seroprevalence and the rate of active urogenital infection were investigated in HIV-infected women without AIDS-defining conditions. Women (71 black, 25 hispanic, 14 other; ages 20-55; 26% hx IVDU) enrolled in the Womens AIDS Cohort Study (WACS) underwent a
Detection of Cryptosporidium in induced sputum using ELISA and direct immunofluorescence.: Abstr Gen Meet Am Soc Microbiol. 1993;93:522 (abstract no. C-431). Unique Identifier : AIDSLINE ASM93/93291853; Atkinson DM; Moore DF; Orange County Public Health Laboratory, Santa Ana, CA.; Cryptosporidium, an intestinal protozoan, is a well recognized cause of diarrhea in AIDS patients. It can also colonize the oropharynx, the trachea and the lungs. Respiratory cryptosporidiosis is a rare complication of intestinal infection in AIDS and immunocompromised patients with only 13 human cases reported since
Diagnosis of intestinal microsporidiosis in AIDS patients by examination of stool and duodenal aspirates with a modified trichrome stain.: Abstr Gen Meet Am Soc Microbiol. 1993;93:522 (abstract no. C-433). Unique Identifier : AIDSLINE ASM93/93291854; Degirolami PC; Desai G; Ezratty C; McCullough A; Federman M; New England Deaconess Hospital, Boston, MA.; Intestinal microsporidiosis caused by Enterocytozoon bieneusi and other microsporidia is an emerging opportunistic infection associated with severe chronic diarrhea in patients with AIDS. Recently a chromotrope based modified trichrome stain (MTS) was described for det
Development of Candida albicans resistance to fluconazole during treatment for thrush over a two year period in AIDS.: Abstr Gen Meet Am Soc Microbiol. 1993;93:527 (abstract no. F-3). Unique Identifier : AIDSLINE ASM93/93291855; Redding S; Smith J; Farinacci G; Pfaller M; Rinaldi M; Fothergill A; Univ. Tx. Hlth Sci Ctr. San Antonio.; It has been reported previously that fluconazole is an effective therapy for thrush in AIDS patients, even over multiple infections. The purpose of this study was to follow a patient with AIDS over multiple infections over a two year period to determine if fluconazole remained
Efficacy of oral (PO) amphotericin B (AB) in AIDS patients with thrush clinically resistant to fluconazole (F).: Abstr Gen Meet Am Soc Microbiol. 1993;93:527 (abstract no. F-2). Unique Identifier : AIDSLINE ASM93/93291856; Dewsnup DH; Stevens DA; Santa Clara Valley Med. Ctr., San Jose, CA.; Reports of thrush in AIDS patients clinically refractory to clotrimazole, ketoconazole and F and resistant to azoles in vitro are increasing with increasing use of these agents. Several cases have been successfully treated with systemic AB. Regarding other PO alternatives, nyst
Analysis of rat T-cell responses to a surface antigen of rat derived Pneumocystis carinii.: Abstr Gen Meet Am Soc Microbiol. 1993;93:530 (abstract no. F-17). Unique Identifier : AIDSLINE ASM93/93291857; Theus S; Linke M; Andrews R; Walzer P; Univ. Cincinnati Coll. Med., OH.; Despite improved diagnosis and therapy, Pneumocystis carinii (Pc) remains a serious threat to the immunocompromised host, particularly patients with the acquired immune deficiency (AIDS). Resistance to Pc appears to involve both a humoral and a cellular immune response. We have previously identified a major surface gl
Geographic clustering of Pneumocystis carinii pneumonia.: Abstr Gen Meet Am Soc Microbiol. 1993;93:534 (abstract no. F-42). Unique Identifier : AIDSLINE ASM93/93291858; Vigdorth E; Hertzberg V; Frame P; Walzer P; Univ Cincinnati, OH.; We have analyzed the epidemiologic features of primary Pneumocystis carinii pneumonia (PcP) occurring in HIV patients over a 4 year period using the data base generated by the AIDS Clinical Trials Unit (ACTU) which cares for > 90% of the AIDS patients in the Cincinnati area. The 118 cases of PcP were compared with two
Structure of the glucuronoxylomannan of Cryptococcus neoformans obtained from patients with AIDS.: Abstr Gen Meet Am Soc Microbiol. 1993;93:543 (abstract no. F-89). Unique Identifier : AIDSLINE ASM93/93291859; Cherniak R; Morris L; Meyer SA; Georgia State Univ. Atlanta.; Structural analyses were done on purified glucuronoxylomannan (GXM) obtained from 3 clinical isolates of C. neoformans. The three isolates, 118, 150, and 194, were serotype A. The GXMs were analyzed by GLC-MS, and 13C NMR spectroscopy. Purified GXMs obtained from 3 isolates of C. neoformans were treated by ultrasonic
Base dissociation assay (BDA), a simplified method for immune-complex dissociation and detection of HIV-1 p24 antigen in serum and plasma.: Abstr Gen Meet Am Soc Microbiol. 1993;93:556 (abstract no. V-22). Unique Identifier : AIDSLINE ASM93/93291860; Hyman J; Lockwood D; Holody T; Youngbar P; Organon Teknika Corp., Durham, NC.; The presence and amount of HIV-1 p24 antigen in serum or plasma from HIV-1 infected individuals has been correlated with viral replication and disease progression. A method for measuring p24 antigen levels is desired as a means of determining patient prognosis and the efficacy of anti-viral therapy. However, measuring
Comparison of a viral lysate based EIA (genetic systems) (GSC) and a recombinant antigen based EIA (Cambridge Biotech) (CB) for detection of antibodies to HIV-1 in hemodialysis (HD) patients.: Abstr Gen Meet Am Soc Microbiol. 1993;93:556 (abstract no. V-23). Unique Identifier : AIDSLINE ASM93/93291861; Carlyn C; Yen-Lieberman B; Paganini E; Rehm SJ; Proffit M; Starkey C; Cleveland Clinic, OH.; Numerous reports describe excessive false positive (FP) HIV-1 EIA rates with most viral lysate based ELISAs in HD pts. This has been explained by Abs to cellular antigens such as DR4. Proposed mechanisms include prior sensitization by multiple transfusions, exposure to nonbiologic surfaces during dialysis triggering i
Evaluation and assessment of the SUDS HIV-1/2 antibody test.: Abstr Gen Meet Am Soc Microbiol. 1993;93:556 (abstract no. V-25). Unique Identifier : AIDSLINE ASM93/93291862; Haynes T; Mazzaferro P; Lowery K; Flowers T; Shockley K; Murex Corporation, Norcross, GA.; Infection with HIV with subsequent development of AIDS requires accurate serologic procedures to identify infected individuals. Since the identification of HIV-1 in 1983 and HIV-2 in 1985/1986, numerous HIV serologic tests have been developed and employed on a truly global scale. Current strategies in most countries r
Evaluation of an indirect immunofluorescence assay for confirmation of human immunodeficiency virus type 1 antibody in previously screened sera.: Abstr Gen Meet Am Soc Microbiol. 1993;93:556 (abstract no. V-24). Unique Identifier : AIDSLINE ASM93/93291863; Steece R; Neumann L; Yendung V; Oty G; Zanto S; Public Health Laboratory Division, Minneapolis, Minnesota 55440.; An indirect immunofluorescence assay (IFA), Fluoroqnost HIV-1 was evaluated as a confirmatory test for antibody to human immunodeficiency virus type 1 in specimens previously submitted and tested by enzyme immunoassay (EIA) and confirmed with Western blot (WB). IFA results were 100% concordant with a licensed WB for 2
Physician satisfaction and opportunities for improving the quality of human immunodeficiency virus type 1 (HIV-1) antibody and hepatitis B virus (HBV) testing.: Abstr Gen Meet Am Soc Microbiol. 1993;93:556 (abstract no. V-26). Unique Identifier : AIDSLINE ASM93/93291864; Peddecord K; Hofherr L; Benenson A; Garfein R; Francis D; Rau J; Cross J; Graduate School of Public Health, San Diego State University.; We surveyed all licensed physicians in San Diego County (N = 6570) on their experiences in use, perceptions of quality, preferences for report content, criteria for choosing a laboratory and problem areas encountered in testing for HIV-1 or HBV. Response rates were 64% for HIV-1 and 65% for HBV including all medical s
[Salmonella osteomyelitis in an AIDS patient (letter)]: An Med Interna. 1989 Nov;6(11):603. Unique Identifier : AIDSLINE MED/93271304; Gato Diez A; Perez Gomez V; Ballesteros Moreno P; Gaspar Alonso-Vega G
[Haemophilus influenzae pneumonia in patients with the human immunodeficiency virus (letter)]: An Med Interna. 1989 Sep;6(9):500-1. Unique Identifier : AIDSLINE MED/93271330; Teira Cobo R; Munoz Sanchez J; Merino Mugica JM; Santamaria Jauregui JM
The virology of AIDS: 1990.: AIDS. 1990;4 Suppl 1:S1-8. Unique Identifier : AIDSLINE MED/93270685; Coffin JM; Department of Molecular Biology and Microbiology, Tufts; University School of Medicine, Boston, MA 02111.
HIV infection and injecting drug users: from epidemiology to public health.: AIDS. 1990;4 Suppl 1:S105-9. Unique Identifier : AIDSLINE MED/93270686; Wodak A; Moss A; Alcohol and Drug Service, St Vincent's Hospital, Sydney,; Australia.
HIV-1 infection in pregnancy: implications for women and children.: AIDS. 1990;4 Suppl 1:S111-7. Unique Identifier : AIDSLINE MED/93270687; Newell ML; Peckham CS; Lepage P; Department of Paediatric Epidemiology, Institute of Child Health,; London, UK.
HIV risks in the health care organization.: AIDS. 1990;4 Suppl 1:S119-22. Unique Identifier : AIDSLINE MED/93270688; Gerberding JL; Department of Medicine and Infectious Diseases, University of; California, San Francisco.; Health-care workers who sustain an accidental parenteral exposure to HIV are at risk of infection. Although only incomplete data are available to assess the risk, these data are reassuring. The most important lesson for health-care workers in the AIDS era is that nearly all risky exposures can and should be prevented.
HIV and design of intervention studies for control of sexually transmitted diseases.: AIDS. 1990;4 Suppl 1:S123-6. Unique Identifier : AIDSLINE MED/93270689; Nkowane BM; Lwanga SK; Global Programme on AIDS, World Health Organization, Geneva,; Switzerland.
AIDS 1990. Vaccines and immunology: overview.: AIDS. 1990;4 Suppl 1:S127-8. Unique Identifier : AIDSLINE MED/93270690; Bolognesi DP; Schild GC; Department of Surgery, Duke University Medical Center, Durham, NC; 27710.
Antigenic variation in HIV.: AIDS. 1990;4 Suppl 1:S129-36. Unique Identifier : AIDSLINE MED/93270691; Putney SD; McKeating JA; Repligen Corporation, Cambridge, Massachusetts.
Progress in the development of simian immunodeficiency virus vaccines: a review.: AIDS. 1990;4 Suppl 1:S137-41. Unique Identifier : AIDSLINE MED/93270692; Gardner MB; Stott J; Department of Medical Pathology, University of California, Davis; 95616-8652.
Progress in the development of HIV vaccines.: AIDS. 1990;4 Suppl 1:S143-50. Unique Identifier : AIDSLINE MED/93270693; Girard MP; Eichberg JW; Pasteur Institute, Paris, France.
Clinical research 1990: a summary.: AIDS. 1990;4 Suppl 1:S15-8. Unique Identifier : AIDSLINE MED/93270694; Collier AC; Department of Medicine, University of Washington School of; Medicine, Seattle.
Neutralization and enhancement of in vitro and in vivo HIV and simian immunodeficiency virus infections.: AIDS. 1990;4 Suppl 1:S151-62. Unique Identifier : AIDSLINE MED/93270695; Robinson WE Jr; Mitchell WM; Department of Pathology, Vanderbilt University, School of; Medicine, Nashville, TN 37232.; Over the past year significant progress has been made in mapping those regions of the HIV-1 envelope glycoproteins involved in virus neutralization and virus enhancement. These functional, antigenic domains of the gp160 are illustrated in Fig. 1. The role of neutralization in vaccine development is still unresolved, a
Research strategies for AIDS vaccine development and evaluation: the MRC programme.: AIDS. 1990;4 Suppl 1:S167-78. Unique Identifier : AIDSLINE MED/93270697; Karn J; Almond JW; Tyrrell DA; MRC Laboratory of Molecular Biology, Cambridge, UK.
AIDS vaccines 1990: a brief update.: AIDS. 1990;4 Suppl 1:S179-84. Unique Identifier : AIDSLINE MED/93270698; Koff WC; Schultz AM; Division of AIDS, National Institute of Allergy and Infectious; Diseases, Bethesda, Maryland.
AIDS 1990. Clinical treatment: overview.: AIDS. 1990;4 Suppl 1:S185-6. Unique Identifier : AIDSLINE MED/93270699; Pinching AJ; Mills J; Department of Immunology, St Mary's Hospital Medical School,; London, UK.
A critical analysis of recent data on zidovudine therapy: use in asymptomatic HIV infection and early HIV disease, dosing and resistance issues.: AIDS. 1990;4 Suppl 1:S187-91. Unique Identifier : AIDSLINE MED/93270700; Peto TE; Nuffield Department of Clinical Medicine, John Radcliffe; Hospital, Oxford, UK.
New messages to caregivers.: AIDS. 1990;4 Suppl 1:S19-22. Unique Identifier : AIDSLINE MED/93270701; Willoughby AD; Pediatric, Adolescent, and Maternal AIDS Branch, National; Institute of Child Health and Human Development, National; Institutes of Health, Bethesda, MD 20892.
New anti-HIV-1 therapies and combinations: current data and prospects.: AIDS. 1990;4 Suppl 1:S193-200. Unique Identifier : AIDSLINE MED/93270702; Eron JJ Jr; Hirsch MS; Infectious Disease Unit, Massachusetts General Hospital, Boston; 02114.
Immunological and virological surrogate markers in the evaluation of therapies for HIV infection.: AIDS. 1990;4 Suppl 1:S201-6. Unique Identifier : AIDSLINE MED/93270703; Valentine FT; Jacobson MA; Department of Medicine, New York University School of Medicine,; New York.
Clinical trials: patient perspectives.: AIDS. 1990;4 Suppl 1:S207-8. Unique Identifier : AIDSLINE MED/93270704; Grimshaw JM; The Landmark, Tulse Hill, London, UK.
Treatment of opportunistic infections.: AIDS. 1990;4 Suppl 1:S209-15. Unique Identifier : AIDSLINE MED/93270705; Feinberg J; Mills J; Division of AIDS, National Institute of Allergy and Infectious; Diseases, National Institutes of Health, Bethesda, Maryland.
Current approaches to the treatment of HIV-related Kaposi's sarcoma and lymphoma by chemotherapy.: AIDS. 1990;4 Suppl 1:S217-21. Unique Identifier : AIDSLINE MED/93270706; Stewart JS; Department of Oncology, St Mary's Hospital, London, UK.
Dermatological aspects of HIV disease: 1990 update.: AIDS. 1990;4 Suppl 1:S223-5. Unique Identifier : AIDSLINE MED/93270707; Berger TG; Department of Dermatology, San Francisco General Hospital, CA; 94110.
Recent advances in the management of the HIV-infected infant [published erratum appears in AIDS 1991 May;5(5):following 615]: AIDS. 1990;4 Suppl 1:S227-34. Unique Identifier : AIDSLINE MED/93270708; Indacochea FJ; Scott GB; Department of Pediatrics, University of Miami, Florida.
The epidemiology of AIDS and HIV infection.: AIDS. 1990;4 Suppl 1:S23-8. Unique Identifier : AIDSLINE MED/93270709; Lifson AR; AIDS Office, Department of Public Health, San Francisco, CA; 94102.
AIDS 1990. Social, cultural and political aspects.: AIDS. 1990;4 Suppl 1:S243-5. Unique Identifier : AIDSLINE MED/93270711; Carballo M; Bayer R; Programme on Substance Abuse, World Health Organization, Geneva,; Switzerland.
Global AIDS: revolution, paradigm and solidarity.: AIDS. 1990;4 Suppl 1:S247-50. Unique Identifier : AIDSLINE MED/93270712; Mann J; Department of Epidemiology, Harvard School of Public Health,; Boston, MA 02115.
HIV-related discrimination.: AIDS. 1990;4 Suppl 1:S251-6. Unique Identifier : AIDSLINE MED/93270713; Tindall B; Tillett G; National Centre in HIV Epidemiology and Clinical Research,; University of New South Wales, Australia.
The psychosocial impact of AIDS on health workers.: AIDS. 1990;4 Suppl 1:S257-62. Unique Identifier : AIDSLINE MED/93270714; Eakin JM; Taylor KM; Department of Behavioural Science, University of Toronto,; Ontario, Canada.
Drug prevention and HIV policy.: AIDS. 1990;4 Suppl 1:S263-7. Unique Identifier : AIDSLINE MED/93270715; Power R; Stimson GV; Strang J; Centre for Research on Drugs and Health Behaviour, Charing Cross; & Westminster Medical School, University of London, UK.
Opportunities for overcoming the continuing restraints to behavior change and HIV risk reduction.: AIDS. 1990;4 Suppl 1:S269-76. Unique Identifier : AIDSLINE MED/93270716; Sittitrai W; Brown T; Sterns J; Institute of Population Studies, Chulalongkorn University,; Thailand.
Global estimates of AIDS cases and HIV infections: 1990.: AIDS. 1990;4 Suppl 1:S277-83. Unique Identifier : AIDSLINE MED/93270717; Chin J; Surveillance, Forecasting and Impact Assessment Unit, World; Health Organization, Geneva, Switzerland.
Psychosocial aspects of AIDS: policy implications.: AIDS. 1990;4 Suppl 1:S29-33. Unique Identifier : AIDSLINE MED/93270718; Carballo M; World Health Organization, Geneva, Switzerland.
Public policy issues.: AIDS. 1990;4 Suppl 1:S35-7. Unique Identifier : AIDSLINE MED/93270719; Helquist MJ; AIDSCOM/Academy for Educational Development, Washington DC 20037.
AIDS 1990. Virology: overview.: AIDS. 1990;4 Suppl 1:S39-40. Unique Identifier : AIDSLINE MED/93270720; Goudsmit J; Martin M; Academisch Medisch Centrum, Department of Virology, Amsterdam,; The Netherlands.
Molecular pathogenesis of HIV-1.: AIDS. 1990;4 Suppl 1:S41-8. Unique Identifier : AIDSLINE MED/93270721; O'Brien WA; Zack JA; Chen IS; Department of Microbiology & Immunology, UCLA School of Medicine,; Jonsson Comprehensive Cancer Center 90024.
Biological and molecular features of HIV-1 related to tissue tropism.: AIDS. 1990;4 Suppl 1:S49-56. Unique Identifier : AIDSLINE MED/93270722; Cheng-Mayer C; Cancer Research Institute, University of California, San; Francisco 94143-0128.
Interactions between HIV and the host immune system in the pathogenesis of AIDS.: AIDS. 1990;4 Suppl 1:S57-66. Unique Identifier : AIDSLINE MED/93270723; Tersmette M; Miedema F; Central Laboratory, Netherlands Red Cross Blood Transfusion; Service, Amsterdam.
Understanding HIV-1 infection of the brain: a challenge for neurobiologists.: AIDS. 1990;4 Suppl 1:S67-76. Unique Identifier : AIDSLINE MED/93270724; Dubois-Dalcq ME; Jordan CA; Kelly WB; Watkins BA; Laboratory of Viral and Molecular Pathogenesis, National; Institute of Neurological Disorders and Stroke, National; Institutes of Health, Bethesda, MD 20892.
Variation in HIV virus load of individuals at different stages in infection: possible relationship with risk of transmission.: AIDS. 1990;4 Suppl 1:S77-83. Unique Identifier : AIDSLINE MED/93270725; Simmonds P; Department of Medical Microbiology, Medical School, University of; Edinburgh, UK.
How old is the immunodeficiency virus?: AIDS. 1990;4 Suppl 1:S85-93. Unique Identifier : AIDSLINE MED/93270726; Eigen M; Nieselt-Struwe K; Max-Planck-Institut fur biophysikalische Chemie, Gottingen,; Germany.
AIDS 1990. Epidemiology: overview.: AIDS. 1990;4 Suppl 1:S95-7. Unique Identifier : AIDSLINE MED/93270728; Winkelstein W Jr; Johnson AM; School of Public Health, University of California, Berkeley; 94720.
Sexual transmission of HIV and the epidemiology of other sexually transmitted diseases.: AIDS. 1990;4 Suppl 1:S99-103. Unique Identifier : AIDSLINE MED/93270729; Cameron DW; Padian NS; Department of Medicine, University of Ottawa, Canada.
[Patients with an indeterminate serological diagnosis of HIV-1 infection]: Rev Med Chil. 1990 Nov;118(11):1235-40. Unique Identifier : AIDSLINE MED/93289103; Ramirez E; Soto G; Mora J; Vera L; Munoz G; Sanchez G; Seccion Virologia, Instituto de Salud Publica, Santiago de; Chile.; Western blot is the technique most frequently used to determine the presence of HIV-1 antibodies. However, some patients remain with an indeterminate diagnosis for HIV-1 according to the technique. We followed 8 such patients for 2 to 18 months. Immunologic studies included standard ELISA, immunofluorescence and Abbot
[HTLV-1 in a Mapuche population]: Rev Med Chil. 1990 Dec;118(12):1326-9. Unique Identifier : AIDSLINE MED/93289119; Inostroza J; Diaz P; Saunier C; Laboratorio Inmunologia, Hospital Regional de Temuco, Chile.; The seroprevalence of HTLV-1 in 405 serum samples from South American Indians, Mapuches, from the IXth region of Chile was investigated using enzyme linked immunosorbent assay (ELISA). Six samples were positive and only 3 of them were also positive by western blot and radio immuno p
[The value of cerebral biopsy in patients with AIDS and extensive cerebral lesions]: Rev Med Chil. 1990 Dec;118(12):1367-71. Unique Identifier : AIDSLINE MED/93289126; Torrealba G; Acuna G; Tagle P; Tapia J; Huete I; Departamento de Neurologia y Neurocirugia, Medicina Interna y; Radiologia, Escuela de Medicina, P. Universidad Catolica de; Chile, Santiago.; We performed cerebral biopsy in 4 patients with AIDS and evidence of expanding intracerebral lesions. Three patients had cerebral toxoplasmosis and the fourth had Chagas encephalitis. No patient developed complications. We feel that cerebral biopsy is warranted and safe in patients with AIDS and intracerebral lesions
Feline immunodeficiency virus as a model for AIDS vaccination.: AIDS. 1990;4 Suppl 1:S163-5. Unique Identifier : AIDSLINE MED/93270696; Jarrett O; Yamamoto JK; Neil JC; Department of Veterinary Pathology, University of Glasgow, UK.
Aids 1990, A Year in Review. Proceedings from the 6th International Conference on AIDS.: AIDS. 1990;4 Suppl 1:S1-285. Unique Identifier : AIDSLINE MED/93270684
Immunology in AIDS in 1990.: AIDS. 1990;4 Suppl 1:S9-14. Unique Identifier : AIDSLINE MED/93270727; Sela M; Department of Chemical Immunology, Weizmann Institute of Science,; Rehovot, Israel.
[New treatments for cryptosporidiosis (letter)]: Rev Med Chil. 1990 Sep;118(9):1037. Unique Identifier : AIDSLINE MED/93303436; Neira P
Special issue on AIDS vaccine developments.: Biotechnol Ther. 1991;2(1-2):1-211. Unique Identifier : AIDSLINE MED/93271826
Idiotypes and anti-idiotypes: an update in potential applications for developing an AIDS vaccine.: Biotechnol Ther. 1991;2(1-2):107-22. Unique Identifier : AIDSLINE MED/93271828; Scinicariello F; Attanasio R; Laghi V; Kennedy RC; Istituto di Clinica delle Malattie Tropicali e Infettive,; Universita degli Studi, La Sapienza, Rome, Italy.
Anti-HIV-1 ADCC: clinical and therapeutic implications.: Biotechnol Ther. 1991;2(1-2):147-57. Unique Identifier : AIDSLINE MED/93271831; Weinhold KJ; Department of Surgery, Duke University Medical Center, Durham,; North Carolina 27710.; The predominant antienvelope cell-mediated cytotoxicity in HIV-1-infected patients is a direct form of antibody-dependent cellular cytotoxicity (ADCC) in which circulating NK/K cells armed with cytophilic antibodies comprise a cytolytic effector cell complex capable of destroying HIV-1-expressing targets. This non-MHC
Development of BCG as a live recombinant vector system: potential use as an HIV vaccine.: Biotechnol Ther. 1991;2(1-2):159-78. Unique Identifier : AIDSLINE MED/93271832; Fuerst TR; Stover CK; de la Cruz VF; Department of Molecular Genetics, MedImmune, Inc., Gaithersburg,; Maryland 20878.; Bacille Calmette-Guerin (BCG), a live attenuated tubercle bacillus, is currently the most widely used vaccine in the world. Because of its unique characteristics, including low toxicity, adjuvant potential, and long-lasting immunity, BCG represents a novel vaccine vehicle with which to deliver protective antigens of m
Induction of anti-HIV-1 immune responses by retroviral vectors.: Biotechnol Ther. 1991;2(1-2):179-93. Unique Identifier : AIDSLINE MED/93271833; Jolly DJ; Warner JF; Viagene, Inc., San Diego, California 92121.; Retroviral vectors encoding HIV-1 proteins, in particular, the envelope from HIV-1 IIIB, have been constructed and used to generate infectious vector particles. Murine cells transduced with these vectors express HIV proteins. Vector-transduced cells, when injected into syngeneic BALB/c mice, induce potent CD8+, class
HIV vaccine development: current status and future challenges.: Biotechnol Ther. 1991;2(1-2):195-203. Unique Identifier : AIDSLINE MED/93271834; Koff WC; Vaccine R&D Branch, National Institute of Allergy and Infectious; Diseases, National Institutes of Health, Bethesda, Maryland; 20892.
HIV vaccine development: perspective.: Biotechnol Ther. 1991;2(1-2):205-11. Unique Identifier : AIDSLINE MED/93271835; Bolognesi DP; Duke University Medical Center, Durham, North Carolina 27710.
Passive immunization for the treatment and prevention of HIV infection.: Biotechnol Ther. 1991;2(1-2):31-48. Unique Identifier : AIDSLINE MED/93271837; Karwowska S; Zolla-Pazner S; Department of Pathology, New York University Medical Center, New; York.; Passive immunization using serum or immunoglobulin preparations has been used in the prophylaxis and treatment of many bacterial and viral diseases. Preliminary attempts to use these methods to prevent HIV infection in chimpanzees have been promising. With the identification of polyclonal and monoclonal antibodies wit
Methods for analysis of biologically functional antibodies to the HIV-1 gp120 principal neutralizing domain.: Biotechnol Ther. 1991;2(1-2):49-62. Unique Identifier : AIDSLINE MED/93271838; Devash Y; Rusche JR; Nara PL; Ortho Diagnostic Systems Inc., Raritan, New Jersey 08869.; The humoral response to HIV-1 infection has been demonstrated by a variety of immunoassays utilizing viral proteins. While several assays detect HIV-1 infection with high sensitivity and great specificity, little progress has been made to develop immunoassays correlative with disease progression and viral transmission
SIV vaccine protection of rhesus monkeys.: Biotechnol Ther. 1991;2(1-2):9-19. Unique Identifier : AIDSLINE MED/93271840; Gardner MB; Carlson JR; Jennings M; Rosenthal A; Langlois A; Haynes B; Bolognesi D; Palker TJ; Department of Medical Pathology, University of California, Davis.; Rhesus macaques (M. mulatta), immunized with an inactivated whole SIVmac vaccine and muramyl dipeptide or Freund s incomplete adjuvant, were protected against IV challenge infection with 10 animal infectious doses of the homologous virus. The protection in these animals appeared to be complete, with no breakthrough of
Characterization of a vaccinia-derived recombinant HIV-1 gp160 candidate vaccine and its immunogenicity in chimpanzees.: Biotechnol Ther. 1991;2(1-2):91-106. Unique Identifier : AIDSLINE MED/93271841; Barrett N; Eder G; Dorner F; Biomedical Research Center, Immuno AG, Orth/Donau, Austria.; The human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 was produced in large-scale microcarrier cultures of Vero cells, using a system involving coinfection with two recombinant vaccinia viruses. The immunogenicity of this material was studied in conjunction with a number of different adjuvant formulatio
Human recombinant IL-6: clinical promise.: Biotechnol Ther. 1991;2(3-4):285-98. Unique Identifier : AIDSLINE MED/93271846; Bauer J; Psychiatrische Universitatsklinik, Universitat Freiburg,; Germany.; The biology of interleukin-6 (IL-6) has been extensively reviewed. This article therefore does not repeat in detail how this molecule was discovered and its cDNA cloned, or the molecular mechanisms of its synthesis, its structural features, and its basic biological functions. Instead, three questions are addressed mor
Peptides containing multideterminant clusters of human immunodeficiency virus envelope induce murine and human T-cell responses in diverse histocompatibility types.: Trans Assoc Am Physicians. 1991;104:69-77. Unique Identifier : AIDSLINE MED/93276513; Berzofsky JA; Pendleton CD; Clerici M; Ahlers J; Lucey DR; Putney SD; Shearer GM; Metabolism Branch, National Cancer Institute, National Institutes; of Health, Bethesda, MD 20892.
Functional analyses of the type I human T-cell leukemia virus tax gene product.: Trans Assoc Am Physicians. 1991;104:78-91. Unique Identifier : AIDSLINE MED/93276514; Smith MR; Greene WC; Howard Hughes Medical Institute, Department of Medicine, Duke; University Medical Center, Durham, NC 27710.
Ethical dilemma in continuing a zidovudine-placebo trial in symptomatic human immunodeficiency virus infection.: Trans Assoc Am Physicians. 1991;104:92-6. Unique Identifier : AIDSLINE MED/93276515; Simberkoff MS; Hartigan PM; Hamilton JD; Infectious Diseases Section, NY VAMC.
AIDS and the duty to treat.: Univ Tor Dent J. 1991 Summer;4(3 Suppl):3p.. Unique Identifier : AIDSLINE MED/93285065; Bassford HA; Department of Philosophy, Atkinson College, York University.
[Sexually transmitted diseases: epidemiological characteristics of cases notified in the health service of Vina del Mar-Quillota]: Rev Med Chil. 1991 Oct;119(10):1213-8. Unique Identifier : AIDSLINE MED/93289154; Fernandez MS; Lopez IM; Servicio de Salud Vina del Mar-Quillota.; During 1987 and 1988 sexually transmitted diseases affected 87.2 per 100,000 inhabitants of the Vina del Mar-Quillota area. At all ages rates were 3.8 times higher in males compared to females. Gonorrhoea, syphilis and non gonorrheal urethritis accounted for most cases. In males, 82% of cases corresponded to gonorrhoe
Acquired immunodeficiency syndrome precautions for otolaryngology-head and neck surgery.: Arch Otolaryngol Head Neck Surg. 1991 Dec;117(12):1343-4. Unique Identifier : AIDSLINE MED/93298285; Davidson TM; Stabile B
Erythema elevatum diutinum in a patient with acquired immunodeficiency syndrome. Another clinical simulator of Kaposi's sarcoma.: Arch Dermatol. 1991 Dec;127(12):1819-22. Unique Identifier : AIDSLINE MED/93304975; Requena L; Sanchez Yus E; Martin L; Barat A; Arias D; Department of Dermatology, Jimenez Diaz Foundation, Nuestra; Senora de la Concepcion Clinic, Universidad Autonoma, Madrid,; Spain.; Several types of vasculitis have been described in patients with human immunodeficiency virus infection. Erythema elevatum diutinum is a rare variant of cutaneous leukocytoclastic vasculitis which, with the exception of the case reported herein, has been described only once in human immunodeficiency virus-infected pat
Papules and nodules in a patient with the acquired immunodeficiency syndrome and recurrent cryptococcal meningitis. Bacillary angiomatosis or epithelioid angiomatosis.: Arch Dermatol. 1991 Dec;127(12):1832-3, 1835-6. Unique Identifier : AIDSLINE MED/93304980; Szych CM; Rotter SM; Gallant JE; Johns Hopkins University Medical Institutions, Baltimore, Md.
Primary cutaneous cryptococcosis in a patient with the acquired immunodeficiency syndrome [letter]: Arch Dermatol. 1991 Dec;127(12):1848-9. Unique Identifier : AIDSLINE MED/93304985; Cusini M; Cagliani P; Grimalt R; Tadini G; Alessi E; Fasan M
Immunodominant antigenic sites in primate immunodeficiency viruses and in vivo protection.: Biotechnol Ther. 1991;2(1-2):21-9. Unique Identifier : AIDSLINE MED/93271836; Norrby E; Putkonen P; Albert J; Fenyo EM; Department of Virology, Karolinska Institute, School of Medicine,; Stockholm, Sweden.
Palliative care in advanced HIV disease: presentation, problems and palliation.: AIDS. 1990;4 Suppl 1:S235-42. Unique Identifier : AIDSLINE MED/93270710; Moss V; Mildmay Mission Hospital, London, UK.
HIV vaccine development: lessons learned to date.: Biotechnol Ther. 1991;2(1-2):1-7. Unique Identifier : AIDSLINE MED/93271827; Putney SD; Repligen Corporation, Cambridge, Massachusetts 02139.
Progress toward an artificial vaccine for HIV: identification of helper and cytotoxic T-cell epitopes and methods of immunization.: Biotechnol Ther. 1991;2(1-2):123-35. Unique Identifier : AIDSLINE MED/93271829; Berzofsky JA; Molecular Immunogenetics and Vaccine Research Section, National; Cancer Institute, National Institutes of Health, Bethesda,; Maryland 20814.; Design of a synthetic vaccine for HIV requires basic knowledge of the structure of helper and cytotoxic T-cell epitopes and neutralizing antibody epitopes, of ways to couple these to produce an effective immunogen, and of the role of viral sequence variation on MHC presentation of antigen. T-cell recognition, and cros
Identification of HIV-1 cytotoxic T-lymphocyte epitopes and implications for vaccine development.: Biotechnol Ther. 1991;2(1-2):137-46. Unique Identifier : AIDSLINE MED/93271830; Johnson RP; Walker BD; Infectious Disease Unit, Massachusetts General Hospital, Boston; 02114.
Importance of conformation on the neutralizing antibody response to HIV-1 gp120.: Biotechnol Ther. 1991;2(1-2):63-89. Unique Identifier : AIDSLINE MED/93271839; Steimer KS; Haigwood NL; Chiron Corporation, Emeryville, California 94608-2916.; We have investigated the role of conformation of HIV-1 gp120 on its potential efficacy as a subunit vaccine. The questions that we set out to answer were: 1) Are there neutralizing antibodies directed to conformational epitopes in gp120? 2) If so, what is the spectrum of virus isolates neutralized by these antibodies?
Characterization of an early thymocyte cell line which is chronically infected with the human immunodeficiency virus.: Trans Assoc Am Physicians. 1991;104:248-57. Unique Identifier : AIDSLINE MED/93276499; Stanley SK; Schnittman SM; Greenhouse JJ; Hatch WC; Lyman WD; Orenstein JM; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, Bethesda, MD 20892.
The Mycoplasma genitalium adhesin protein and several human class II MHC proteins exhibit sequence homology: possible ramifications for the development of autoimmunity [letter]: Autoimmunity. 1992;14(2):167-8. Unique Identifier : AIDSLINE MED/93271379; Bisset LR
A molecular model for membrane fusion based on solution studies of an amphiphilic peptide from HIV gp41.: Protein Sci. 1992 Nov;1(11):1454-64. Unique Identifier : AIDSLINE MED/93271895; Fujii G; Horvath S; Woodward S; Eiserling F; Eisenberg D; Molecular Biology Institute, University of California, Los; Angeles 90024-1570.; The mechanism of protein-mediated membrane fusion and lysis has been investigated by solution-state studies of the effects of peptides on liposomes. A peptide (SI) corresponding to a highly amphiphilic C-terminal segment from the envelope protein (gp41) of the human immunodeficiency virus (HIV) was synthesized and tes
[Pulmonary tuberculosis in a man infected with HIV (published erratum appears in Pneumonol Alergol Pol 1993;61(7-8):434)]: Pneumonol Alergol Pol. 1992;60(11-12):77-81. Unique Identifier : AIDSLINE MED/93271917; Zajaczkowska J; Krakowka P; Jodkowski W; Kaminska E; Babiuch L; I Kliniki Gruzlicy i Chorob Pluc Instytutu Gruzlicy i Chorob; Pluc.
[The numbers and distribution studies of natural killer cell, T cell subsets in peripheral blood and local infiltration in patients with squamous cell carcinoma of the oral cavity]: Chung Hua Kou Chiang Hsueh Tsa Chih. 1992 Jul;27(4):225-7. Unique Identifier : AIDSLINE MED/93272592; Pan L
Distribution and trends of HIV infection in blood donors of four metropolitan cities.: Indian J Public Health. 1992 Jul-Sep;36(3):101-4. Unique Identifier : AIDSLINE MED/93273455; Makro RN; Salil P; Bhushan B; Lal S; Screening for HIV infection has been made mandatory for every unit of blood collected for transfusion in major cities of the country, having facilities for such screening. Results of HIV screening among blood donors received from the 4 Metropolitan cities of Delhi, Bombay, Calcutta and Madras have been analysed year w
Presidential address. Public health.: Indian J Public Health. 1992 Oct-Dec;36(4):105-8. Unique Identifier : AIDSLINE MED/93273464; Anjaneyulu G
Human contraception: development of new scientific opportunities.: J Reprod Fertil Suppl. 1992;45:175-92. Unique Identifier : AIDSLINE MED/93274658; Lincoln DW; MRC Reproductive Biology Unit, Centre for Reproductive Biology,; Edinburgh, UK.; Our current methods of contraception were largely developed in the 1950s and 1960s. Collectively these methods can limit population growth, although their acceptability at a personal level remains marginal. The number of abortions in the UK has risen progressively, from 170,000 in 1990, and more
Changing convictions with changing journals? [letter] [see comments]: Natl Med J India. 1992 Jan-Feb;5(1):39-40. Unique Identifier : AIDSLINE MED/93278161; Kulkarni V
HIV surveillance [letter; comment]: Natl Med J India. 1992 Mar-Apr;5(2):97. Unique Identifier : AIDSLINE MED/93278191; Rodrigues JJ
AIDS epidemic [letter]: Natl Med J India. 1992 May-Jun;5(3):144. Unique Identifier : AIDSLINE MED/93278206; Weeks JL
T cell subpopulations in amoebic liver abscess.: Natl Med J India. 1992 Jul-Aug;5(4):166-8. Unique Identifier : AIDSLINE MED/93278214; Tandon A; Agarwal SK; Saha K; Maulana Azad Medical College, New Delhi, India.; BACKGROUND. Cellular immunity may play a major role in the pathogenesis of amoebic liver abscess but there is little data on the effect of treatment on T cell subpopulations in such patients. METHODS. We performed a prospective, controlled study of the T lymphocyte subpopulations in 17 patients with amoebic liver absc
Nucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution-state structure of the nucleocapsid protein from HIV-1.: Protein Sci. 1992 May;1(5):563-74. Unique Identifier : AIDSLINE MED/93278285; Summers MF; Henderson LE; Chance MR; Bess JW Jr; South TL; Blake PR; Sagi I; Perez-Alvarado G; Sowder RC 3d; Hare DR; et al; Department of Chemistry and Biochemistry, University of Maryland; Baltimore County 21228.; All retroviral nucleocapsid (NC) proteins contain one or two copies of an invariant 3Cys-1His array (CCHC = C-X2-C-X4-H-X4-C; C = Cys, H = His, X = variable amino acid) that are essential for RNA genome packaging and infectivity and have been proposed to function as zinc-binding domains. Although the arrays are capabl
Crystal structure of a complex of HIV-1 protease with a dihydroxyethylene-containing inhibitor: comparisons with molecular modeling.: Protein Sci. 1992 Aug;1(8):1061-72. Unique Identifier : AIDSLINE MED/93278318; Thanki N; Rao JK; Foundling SI; Howe WJ; Moon JB; Hui JO; Tomasselli AG; Heinrikson RL; Thaisrivongs S; Wlodawer A; Macromolecular Structure Laboratory, NCI-Frederick Cancer; Research and Development Center, ABL-Basic Research Program,; Maryland 21702.; The structure of a crystal complex of recombinant human immunodeficiency virus type 1 (HIV-1) protease with a peptide-mimetic inhibitor containing a dihydroxyethylene isostere insert replacing the scissile bond has been determined. The inhibitor is Noa-His-Hch psi [CH(OH)CH(OH)]Vam-Ile-Amp (U-75875), and its Ki for in
In situ hybridisation: principles and applications.: Malays J Pathol. 1992 Dec;14(2):69-76. Unique Identifier : AIDSLINE MED/93280882; Looi LM; Cheah PL; Department of Pathology, Faculty of Medicine, University of; Malaya, Kuala Lumpur.; In situ hybridisation (ISH) is based on the complementary pairing of labelled DNA or RNA probes with normal or abnormal nucleic acid sequences in intact chromosomes, cells or tissue sections. Compared with other molecular biology techniques applicable to anatomical pathology, ISH enjoys better rapport with histopathol
[Tuberculosis of bronchi and lymph nodes mimicking cancer in a patient with HIV-infection (letter)]: Rev Pneumol Clin. 1992;48(6):282-4. Unique Identifier : AIDSLINE MED/93281872; Coulibaly G; N'Dhatz M; Domoua K; Traore F; Quattara B; Vincent A; Kouassi Y; Zougba A; Konan JB; Yapi A
Polysaccharide-coated liposomal amphotericin B for the treatment of murine pulmonary candidiasis.: Tohoku J Exp Med. 1992 Nov;168(3):483-90. Unique Identifier : AIDSLINE MED/93281973; Miyazaki T; Kohno S; Sasayama K; Inoue Y; Hara K; Ogasawara M; Sato T; Sunamoto J; Second Department of Internal Medicine, Nagasaki University; School of Medicine.; Amylopectin-coated liposomal amphotericin B was investigated in a murine model of pulmonary candidiasis. The LD50 of amylopectin-coated liposomal amphotericin B in normal mice was more than 10.0 mg/kg, and that of conventional amphotericin B was 1.2 mg/kg. Amylopectin-coated liposomes showed twice the concentration in
AIDS awareness amongst school teachers in a rural area of India.: Asia Pac J Public Health. 1992-93;6(1):16-7. Unique Identifier : AIDSLINE MED/93283193; Srivastava VK; Nirupam S; Chandra R; Jain VC; Department of Social & Preventive Medicine, King George's Medical; College, Lucknow, India.; One hundred and eighty-two teachers from a random selection of 15 schools in a rural area of Lucknow district of northern India were interviewed to assess their awareness and knowledge about AIDS using a pretested CARC proposed questionnaire. Observations revealed that only 79.7% of
Peptide models of the Tat-TAR protein-RNA interaction.: Protein Sci. 1992 Dec;1(12):1539-42. Unique Identifier : AIDSLINE MED/93284092; Frankel AD; Department of Biochemistry and Biophysics, University of; California, San Francisco 94143.
Overview: infectious disease policies.: Dentistry. 1992 Dec;12(4):17-8. Unique Identifier : AIDSLINE MED/93284954; Oldham D
[Spontaneous proliferative activity of lymphocytes in normal and EPH gestosis complicated pregnancy]: Ginekol Pol. 1992;63(7):329-36. Unique Identifier : AIDSLINE MED/93285493; Malinowski A; Szpakowski M; Tchorzewski H; Zeman K; Kowalczyk T; Oszukowski P; Katedry Poloznictwa i Ginekologii WAM, Lodzi.; The spontaneous proliferative activity of lymphocytes and CD4+/CD8+ ratio has been estimated in normal and EPH gestosis-affected pregnancy; also the effects of autologous and allogenic sera on this lymphocyte activity was evaluated. Although in normal pregnancy there was a very low CD4+/CD8+ ratio, the spontaneous pro
[Association of Medical Doctors for Asia held AIDS conference--prevention of AIDS is becoming an urgent problem in Japan]: Kango. 1992 Jan;44(1):62-8. Unique Identifier : AIDSLINE MED/93287463; Kobayashi Y
Disabilities Act and AIDS [news]: N J Med. 1992 Jul;89(7):503. Unique Identifier : AIDSLINE MED/93288284
Tuberculosis--the next plague?: West Engl Med J. 1992 Aug;107(2):37. Unique Identifier : AIDSLINE MED/93290934; Burton BJ; U.C.M.S.M., London.
Application of information systems to AIDS risk reduction.: Med Inf (Lond). 1992 Oct-Dec;17(4):199-214. Unique Identifier : AIDSLINE MED/93295142; Li LX; Xu LD; Department of Management Sciences, Ohio State University,; Columbus 43210.; Acquired immune deficiency syndrome (AIDS) is a specific group of diseases which are indicative of severe immunosuppression related to infection with the human immunodeficiency virus (HIV). In response to the epidemic, a variety of intervention and prevention has been instituted. In such intervention and prevention ac
Comparative evaluation of HIV infected foreign students and Indian with AIDS in Chandigarh, India.: Asian Pac J Allergy Immunol. 1992 Dec;10(2):141-3. Unique Identifier : AIDSLINE MED/93298193; Sehgal S; Department of Immunopathology Postgraduate Institute of Medical; Education and Research, Chandigarh, India.; Out of a total of 1,600 foreign students who came to India between June 1989 and October 1990, 22 were seropositive for HIV-1. Ten showed antibodies to all the gene products. Antibodies to gp160 and p24 were present in all the seropositives while antibodies to p53, p15/17 were signi
[Transgenesis and gene therapy]: C R Seances Soc Biol Fil. 1992;186(5):567-74. Unique Identifier : AIDSLINE MED/93299716; Jeanteur P; Institut de Genetique et Biologie cellulaire CNRS, Montpellier.; There are now rather straightforward methods to create transgenic animals whose genome is altered at the germline level. One method consists in the micro-injection of a gene into the pronucleus of a fertilized egg, the second one involves an homologous recombination event obtained in embryonic stem cells in culture. O
HIV and breast-feeding [news]: Midwives Chron. 1992 Nov;105(1258):371. Unique Identifier : AIDSLINE MED/93302562
[Survey on HIV and the control of infection]: Rev Belge Med Dent. 1992;47(3):40-51. Unique Identifier : AIDSLINE MED/93303339; Prieels F; De Cock P; Hop. Univ. St. Pierre, U.L.B., Service de Stomatologie et de; Chirurgie Maxillo-Faciale, Bruxelles.; During FDI World Dental Congress 1990, field specialists set up a scientific question form to obtain specific information about hygiene procedures in dental offices, knowledge about oral lesions in HIV infection and attitude against HIV infected patients. 540 Belgian dentists replied the question forms correctly. In g
Synthetic interface peptides alter dimeric assembly of the HIV 1 and 2 proteases.: Protein Sci. 1992 Oct;1(10):1244-53. Unique Identifier : AIDSLINE MED/93271870; Babe LM; Rose J; Craik CS; Department of Pharmaceutical Chemistry, University of California,; San Francisco 94143-0446.; Retroviral proteases are obligate homodimers and play an essential role in the viral life cycle. Dissociation of dimers or prevention of their assembly may inactivate these enzymes and prevent viral maturation. A salient structural feature of these enzymes is an extended interface composed of interdigitating N- and C-
[Cytomegalovirus retinitis in AIDS. Effectiveness and complications of long-term therapy]: Ophthalmologe. 1992 Oct;89(5):416-26. Unique Identifier : AIDSLINE MED/93278075; Schmitz K; Fabricius EM; Popescu M; Augenabteilung, Stadtisches Krankenhaus, Munchen-Harlaching.; In a retrospective study of the records of 64 patients with AIDS and cytomegalovirus ( CMV ) retinitis, 47 patients were evaluated regarding the effectiveness of initial virustatic therapy, and 41 patients regarding the anatomi
Historical progress and the future of human cell culture research.: Hum Cell. 1992 Dec;5(4):313-33. Unique Identifier : AIDSLINE MED/93283323; Moore GE; Minowada J; University of Colorado Medical Center, Division of Surgical; Oncology, Denver General Hospital.; Progress in human cell culture research is discussed based primarily on our hematopoietic cell culture studies. The article includes a historical background of Burkitt lymphoma cell lines, discovery of EBV, normal B-lymphoblastoid cell lines with EBV, a variety of leukemia, lymphoma, and myeloma cell lines, clinical a
Ethical concerns in AIDS, a national workshop organized by the FIAMC Bio-medical Ethics Centre, Bombay, 27-28 April 1991.: Natl Med J India. 1992 Jan-Feb;5(1):46. Unique Identifier : AIDSLINE MED/93278169; Vas CJ; De Souza EJ
Quality assurance of immunophenotyping [editorial]: Asian Pac J Allergy Immunol. 1992 Dec;10(2):85-7. Unique Identifier : AIDSLINE MED/93298197; Bradley J
[Hepatitis C virus antibodies in patients and the normal population]: Beitr Infusionsther. 1992;30:13-6. Unique Identifier : AIDSLINE MED/93278466; Knodler B; Kuhnl P; Lubitz B; Roos D; Becks M; Gutensohn K; Abt. fur Transfusionsmedizin und Transplantationsimmunologie,; Universitats-Krankenhaus Eppendorf, Hamburg, BRD.; With regard to the controversial issue of a reduction of transfusion-associated infections by non-remunerated donations, epidemiological data on the prevalence of HIV-1, HIV-2 and hepatitis C virus (HCV) are of particular interest in our country. We investigated four sample categories: (1) healthy employees and worker
Detection of antibodies to HCV: comparison of a c100-3 EIA and the 2nd generation EIA.: Beitr Infusionsther. 1992;30:42-5. Unique Identifier : AIDSLINE MED/93278528; Polywka S; Kaars-Wiele P; Schroeter E; Mandler J; Laufs R; Institute of Medical Microbiology and Immunology, University; Hospital Eppendorf, Hamburg, FRG.; The reactivity of 558 serum specimens in Abbott 1st and 2nd generation EIAs was compared. A significant increase in HCV seropositivity was especially found in high risk groups such as hemophiliacs (57.7 vs. 73.1%), IVDA (54.5 vs. 61.8%), HIV positives (21.8 vs. 25.5%) or patients on dialysis (15.7 vs. 16.9%). Reactivi
Recombinant antigens in viral diagnosis.: Beitr Infusionsther. 1992;30:78-81. Unique Identifier : AIDSLINE MED/93278552; Vornhagen R; Baur A; Jahn G; Hinderer W; Nebel-Schickel H; Horn J; Wolf H; Sonneborn HH; Biotest AG, Research Department, Dreieichenhain, FRG.; DNA fragments coding for a variety of different viral antigens have been cloned and expressed in Escherichia coli. Selected purified recombinant antigens were used for detection of specific antibodies by means of the ELISA technique. This approach has been used for the development of four different ELISAs for the dete
[Follow-up of blood donors with indeterminate reaction to anti-HIV 1/2 EIA or isolated detection of antibodies to HIV-1 core antigens (anti-p24)]: Beitr Infusionsther. 1992;30:82-4. Unique Identifier : AIDSLINE MED/93278553; Zimmermann R; Zeiler T; Zingsem J; Weisbach V; Muller C; Huhn D; Eckstein R; Abteilung Innere Medizin, Universitatsklinikum Rudolf-Virchow,; Freie Universitat Berlin, BRD.; Over a period of 20 months we identified 10 voluntary blood donors with indeterminate reactions in anti-HIV 1/2 EIA tests. Western blot (WB) patterns of 6 of these 10 donors showed isolated core antibodies (anti-p24), in 4 cases WB patterns were negative. After a median follow-up period of 58 weeks (range 12-93) we ha
Carbohydrate binding properties of the envelope glycoproteins of human immunodeficiency virus type 1.: Glycoconj J. 1992 Dec;9(6):315-23. Unique Identifier : AIDSLINE MED/93291559; Haidar M; Seddiki N; Gluckman JC; Gattegno L; Laboratoire de Biologie Cellulaire, Faculte de Medecine Paris; Nord, Bobigny, France.; Here, we confirm and extend our previous findings on human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein N-acetylglucosaminyl binding properties. We show the occurrence of saturable, temperature, pH, and calcium dependent carbohydrate-specific interactions between recombinant precursor gp160 (rgp160) and
Microbial antigens and cytokines cause type I allergic reactions in AIDS patients. In vitro studies of basophil histamine release.: Pneumonol Alergol Pol. 1992;60 Suppl 2:74-9. Unique Identifier : AIDSLINE MED/93291744; Pedersen M; Permin H; Kristensen KS; Norn S; Laboratory of Immunology, University Clinic for Infectious; Diseases, Rigshospitalet, Copenhagen.
Prevention of transmission of HIV by organ and tissue transplantation. HIV testing protocol and a proposal for recommendations concerning donor selection.: Transpl Int. 1993 May;6(3):165-72. Unique Identifier : AIDSLINE MED/93270665; Patijn GA; Strengers PF; Harvey M; Persijn G; Eurotransplant Foundation, Leiden, The Netherlands.; Human immunodeficiency virus (HIV) can be transmitted by solid organ and some forms of tissue transplantation. Although routine screening of organ and tissue donors for anti-HIV antibodies was implemented in most Western European countries and North America in 1985, several recent case reports indicate that a definite
[Professional strength creates enthusiasm and growth (interview by Siv Barstad)]: J Sykepleien. 1993 Feb 16;81(3):10-1. Unique Identifier : AIDSLINE MED/93270835; Aune E
[Give patients identity (interview by Siv Barstad)]: J Sykepleien. 1993 Feb 16;81(3):17-9. Unique Identifier : AIDSLINE MED/93270840; Lauvsnes M
[St. Lucia: safe sex instead of abstinence]: J Sykepleien. 1993 Feb 16;81(3):20. Unique Identifier : AIDSLINE MED/93270842; Ninvalle P
[AIDS in Tanzania]: J Sykepleien. 1993 Apr 20;81(7):5-11. Unique Identifier : AIDSLINE MED/93270867; Barstad S
It is time to be HIV interrogative [letter]: Nurs Stand. 1993 Mar 31-Apr 6;7(28):41. Unique Identifier : AIDSLINE MED/93270952; Hollings L
Education needed after AZT failure [news]: Nurs Stand. 1993 Apr 7-13;7(29):6. Unique Identifier : AIDSLINE MED/93270971
'Blind spot' theory for HIV's damaging power [news]: Nurs Stand. 1993 Apr 14-20;7(30):17. Unique Identifier : AIDSLINE MED/93270972
Haemophilia nurses ask to be warned [news]: Nurs Stand. 1993 Apr 14-20;7(30):7. Unique Identifier : AIDSLINE MED/93270987
Unions support HIV guidance [news]: Nurs Stand. 1993 Apr 14-20;7(30):7. Unique Identifier : AIDSLINE MED/93270988
Funding cut for HIV and AIDS [news]: Nurs Stand. 1993 Apr 14-20;7(30):8. Unique Identifier : AIDSLINE MED/93270989
New treatment helpful in Kaposi's sarcoma [news]: Nurs Stand. 1993 May 19-25;7(35):17. Unique Identifier : AIDSLINE MED/93270990
Witch hunting HIV in the workplace [letter]: Nurs Stand. 1993 May 19-25;7(35):41. Unique Identifier : AIDSLINE MED/93271000; Moore G
Rude health.: Nurs Stand. 1993 May 19-25;7(35):49. Unique Identifier : AIDSLINE MED/93271002; Cook R
[Disease caused by Mycobacterium kansasii in patients with HIV infection]: Enferm Infecc Microbiol Clin. 1993 Mar;11(3):120-5. Unique Identifier : AIDSLINE MED/93271264; Urkijo JC; Montejo M; Aguirrebengoa K; Urra E; Aguirre C; Catedra de Patologia Medica, Universidad del Pais Vasco,; Baracaldo, Vizcaya.; BACKGROUND: To describe the clinical features and response to therapy in Mycobacterium kansasii disease among HIV infected patients, an increasing problem in our setting. METHODS: A retrospective survey of all charts from patients with HIV infection with Mycobacterium kansasii infection recorded between April 1985 and
[Prolonged fever and pulmonary lesions in an intravenous drug addict]: Enferm Infecc Microbiol Clin. 1993 Mar;11(3):159-60. Unique Identifier : AIDSLINE MED/93271272; Mayoral L; Fernandez A; Leon E; Garcia-Bragado F; Lozano de Leon F; Unidad de Enfermedades Infecciosas, Hospital Universitario de; Valme, Sevilla.
[Campylobacter jejuni sepsis in a patient with HIV infection and chronic hepatopathy (letter)]: Enferm Infecc Microbiol Clin. 1993 Mar;11(3):166-7. Unique Identifier : AIDSLINE MED/93271279; Padilla B; Gomez J; Delgado-Iribarren A; Wilhelmi I; Jusdado JJ
[Evaluation of blood culture in the diagnosis of tuberculosis and other mycobacterioses in immunocompromised patients (letter)]: Enferm Infecc Microbiol Clin. 1993 Mar;11(3):167-8. Unique Identifier : AIDSLINE MED/93271280; Dorronsoro I; Garcia-Lechuz JM; Garcia-Irure JJ; Gorriz I
Persistent polyclonal lymphocytosis in human immunodeficiency virus-1-infected patients.: Blood. 1993 Jun 1;81(11):3015-21. Unique Identifier : AIDSLINE MED/93271487; Zambello R; Trentin L; Agostini C; Francia di Celle P; Francavilla E; Barelli A; Cerutti A; Siviero F; Foa R; Semenzato G; Padua University School of Medicine, Italy.; In this study we describe the clinical, morphologic, immunologic, and genetic features of a chronic peripheral blood lymphocytosis associated with posttraumatic splenectomy in patients with human immunodeficiency virus-1 (HIV-1) infection. Among a series of 2,365 consecutive HIV-1 seropositive cases investigated, eigh
Youth coping with sexual orientation issues.: J Sch Nurs. 1993 Apr;9(2):26-7, 30-9. Unique Identifier : AIDSLINE MED/93271588; Taylor BA; Remafedi G; Youth who are struggling with the issue of sexual orientation often are aware of hostile attitudes within their families, schools, communities and among their peers, but are unable to find help. These young people are subject to humiliation, rejection, social isolation, and physical assaults, as well as life-threateni
Should we admit immigrants with AIDS? [news]: Trends Health Care Law Ethics. 1993 Spring;8(2):5-6. Unique Identifier : AIDSLINE MED/93271609; Stolman CJ
HIV/AIDS and nursing: an ethical debate.: Contemp Nurse. 1993 Apr;2(1):29-34. Unique Identifier : AIDSLINE MED/93271638; Kisse T; The purpose of this discussion is to provide the reader with a dual opportunity. It encompasses various ethical paradigms and concepts, thus broadening the horizons of those interested in the ethical processes. Furthermore, it deals with issues pertaining to AIDS/Human Immunodeficiency Virus (HIV) in an ethical framew
[Laboratory diagnosis of immune deficiency]: Infusionsther Transfusionsmed. 1993 Apr;20 Suppl 1:56-67. Unique Identifier : AIDSLINE MED/93271675; Wick M; Fateh-Moghadam A; Institut fur Klinische Chemie am Klinikum Grosshadern,; Ludwig-Maximilians-Universitat, Munchen.; Highly specialized, state-of-the-art diagnostic tests are available for identifying congenital and acquired immune defects. These methods should only be resorted to when less complicated means have created suspicion of an immune defect. The case history, including the family history, represents the core of the diagnos
Japan: pill vetoed for fear of AIDS [news]: Birth Gaz. 1993 Spring;9(2):20. Unique Identifier : AIDSLINE MED/93271737
Universal named testing of pregnant women for HIV [editorial] [see comments]: BMJ. 1993 May 1;306(6886):1144-5. Unique Identifier : AIDSLINE MED/93271748; Goldberg DJ; Johnstone FD
New clinics for HIV testing. Improve public access [letter; comment]: BMJ. 1993 May 1;306(6886):1197. Unique Identifier : AIDSLINE MED/93271774; Beeching NJ; Nye FN; Prior M; Morrison C; Ruben SM; Mutton KJ
New clinics for HIV testing. New clinics offer choice [letter; comment]: BMJ. 1993 May 1;306(6886):1197. Unique Identifier : AIDSLINE MED/93271775; Hayes CJ
New clinics for HIV testing. Upgrade existing services [letter; comment]: BMJ. 1993 May 1;306(6886):1197. Unique Identifier : AIDSLINE MED/93271776; Drake S; Skidmore S; White D
Guidelines for HIV. Health workers have rights too [letter; comment]: BMJ. 1993 May 1;306(6886):1201-2. Unique Identifier : AIDSLINE MED/93271783; Manyonda IT; Kabukoba JJ
Guidelines for HIV. Health workers need protection [letter]: BMJ. 1993 May 1;306(6886):1202. Unique Identifier : AIDSLINE MED/93271784; MacDonald EB
Guidelines for HIV. Sensible approach restores confidence [letter; comment]: BMJ. 1993 May 1;306(6886):1202. Unique Identifier : AIDSLINE MED/93271785; Roy RB; Harindra V
HIV Guidelines for HIV. Cost of compulsory HIV testing [letter; comment]: BMJ. 1993 May 1;306(6886):1202. Unique Identifier : AIDSLINE MED/93271786; Tolley K; Kennelly J
Hemophilia and HIV infection [letter; comment]: Can Med Assoc J. 1993 Jun 1;148(11):1870-1. Unique Identifier : AIDSLINE MED/93272140; Page D
Guidelines for the identification, investigation and treatment of individuals with concomitant tuberculosis and HIV infection. Bureau of Communicable Disease Epidemiology, Canada Department of National Health and Welfare.: Can Med Assoc J. 1993 Jun 1;148(11):1963-70. Unique Identifier : AIDSLINE MED/93272152; The following recommended guidelines, jointly prepared by the Canadian Thoracic Society, the Tuberculosis Directors of Canada , and the Department of National Health and Welfare in consultation with the provincial and territorial epidemiologists, AIDS coordinators and HIV caregivers
The impaired in vitro production of interleukin-2 in HIV infection is negatively correlated to the number of circulating CD4+DR+ T cells and is reversed by allowing T cells to rest in culture: arguments for in vivo CD4+ T cell activation.: Clin Immunol Immunopathol. 1993 Jun;67(3 Pt 1):185-91. Unique Identifier : AIDSLINE MED/93272464; Lees O; Ramzaoui S; Gilbert D; Borsa F; Humbert G; Leblanc D; Lagarde M; Tron F; Laboratoire d'Immunologie, Hopital Charles Nicolle, Rouen,; France.; In HIV infection, several arguments suggest a certain degree of CD4+ T cell activation which might contribute to lymphocyte dysfunctions. To investigate this possibility, we determined the phenotypes of circulating CD4+ T cells using monoclonal antibodies directed to activation markers and examined whether the defecti
GM3 as a target of anti-lymphocytic ganglioside antibodies in AIDS patients.: Clin Immunol Immunopathol. 1993 Jun;67(3 Pt 1):216-23. Unique Identifier : AIDSLINE MED/93272469; Misasi R; Sorice M; Griggi T; d'Agostino F; Garofalo T; Masala C; Pontieri GM; Lenti L; Dipartimento di Medicina Sperimentale, Universita La Sapienza,; Roma, Italy.; IgG antibodies reacting with the GM3-comigrating band extracted from pooled AIDS lymphocytes were detected in 33.3% of AIDS patients sera, in 8% of asymptomatic anti-HIV-positive subjects, in none of the sera obtained from asymptomatic anti-HIV-negative drug abusers, from patients with acute B and chronic C hepatitis,
Successful treatment of microsporidial keratoconjunctivitis with topical fumagillin in a patient with AIDS.: Cornea. 1993 May;12(3):261-5. Unique Identifier : AIDSLINE MED/93272548; Rosberger DF; Serdarevic ON; Erlandson RA; Bryan RT; Schwartz DA; Visvesvara GS; Keenan PC; Department of Ophthalmology, New York Hospital, Cornell; University Medical College, New York.; There recently have been several reports of microsporidial keratoconjunctivitis caused by the organism Encephalitozoon hellem. However, treatment of this infection has been largely ineffective. We report a case of a 35-year-old Hispanic woman with AIDS and E. hellem keratoconjunctivitis confirmed with light, electron,
Recurrent corneal infections in a patient with the acquired immunodeficiency syndrome.: Cornea. 1993 May;12(3):266-9. Unique Identifier : AIDSLINE MED/93272549; Hemady RK; Griffin N; Aristimuno B; Department of Ophthalmology, University of Maryland School of; Medicine, Baltimore 21201.; A 29-year-old female intravenous drug abuser infected with the human immunodeficiency virus suffered recurrent, bilateral corneal infections over an 11-month period. Multiple infectious organisms were responsible, including capnocytophaga species, Candida albicans, Staphylococcus aureus, coagulase-negative staphylococ
Mandatory HIV testing: a timely controversy.: Dimens Crit Care Nurs. 1993 Mar-Apr;12(2):92-9. Unique Identifier : AIDSLINE MED/93272640; Noll ML; Merrell R; Byers JF; Incidence of infection with the human immunodeficiency virus (HIV) has increased to epidemic proportions. Strategies are needed to prevent transmission of the virus. One strategy, mandatory HIV testing of nurses, is controversial. Both sides of this issue are debated in this article.
[The Saccharomyces boulardii therapy of HIV-associated diarrhea (letter)]: Dtsch Med Wochenschr. 1993 May 21;118(20):765. Unique Identifier : AIDSLINE MED/93272686; Born P; Lersch C; Zimmerhackl B; Classen M
Risky decision making and allocation of resources for leukemia and AIDS programs.: Health Psychol. 1993 Mar;12(2):110-7. Unique Identifier : AIDSLINE MED/93272708; Levin IP; Chapman DP; Department of Psychology, University of Iowa, Iowa City 52242.; Traditional judgment and decision-making paradigms were expanded to include differential reactions to persons with leukemia or AIDS. Experiments 1 and 2 adopted Tversky and Kahneman s risky-decision-making task and found support for different value functions for the 2 patient groups when choosing between treatment pro
Factors associated with severity of depression and high-risk sexual behavior among persons diagnosed with human immunodeficiency virus (HIV) infection.: Health Psychol. 1993 May;12(3):215-9. Unique Identifier : AIDSLINE MED/93272722; Kelly JA; Murphy DA; Bahr GR; Koob JJ; Morgan MG; Kalichman SC; Stevenson LY; Brasfield TL; Bernstein BM; St. Lawrence JS; Department of Psychiatry and Mental Health Sciences, Medical; College of Wisconsin, Milwaukee 53226.; Whereas some people appear to cope after learning that they have human immunodeficiency virus (HIV) infection, others experience depression and suicidal ideation. In this study, 142 persons with HIV infection were administered the Center for Epidemiological Studies Depression Scale (CES-D). High levels of depression w
Decision-making orientation and AIDS-related knowledge, attitudes, and behaviors of Hispanic, African-American, and white adolescents.: Health Psychol. 1993 May;12(3):227-34. Unique Identifier : AIDSLINE MED/93272724; Langer LM; Zimmerman RS; Warheit GJ; Duncan RC; Department of Sociology, University of Miami, Coral Gables,; Florida 33124-2208.; How adolescents personal sense of directedness (i.e., peer, parent, or self-directed orientation) affects the decision-making processes of adolescent students regarding AIDS-related knowledge, attitudes, beliefs, behaviors, and skills (KABBS) is examined. The sample consisted of 10th-grade students in 8 public high s
Correct and incorrect interpretations of correlations between risk perceptions and risk behaviors.: Health Psychol. 1993 May;12(3):235-45. Unique Identifier : AIDSLINE MED/93272725; Weinstein ND; Nicolich M; Department of Human Ecology, Rutgers-State University of New; Jersey, New Brunswick.; Correlations between risk perceptions and risk behaviors are used by investigators to answer 2 important and easily confused questions: Are individuals perceptions of their personal risk accurate, correctly reflecting their precautions and their risk-increasing behaviors? and Does recognition of high personal risk ca
Antibody response to a major human Pneumocystis carinii surface antigen in patients without evidence of immunosuppression and in patients with suspected atypical pneumonia.: Eur J Clin Microbiol Infect Dis. 1993 Feb;12(2):105-9. Unique Identifier : AIDSLINE MED/93272750; Lundgren B; Lebech M; Lind K; Nielsen JO; Lundgren JD; Department of Infectious Diseases, University of Copenhagen,; Hvidovre Hospital, Denmark.; IgG and IgM antibodies to a purified human Pneumocystis carinii surface antigen (gp95) were measured in 694 serum specimens from two different population groups using an EIA technique. In a population of 441 patients with no evidence of immunosuppression, the percentage of persons positive for IgG antibodies to gp95 w
A cluster of four cases of Mycobacterium haemophilum infection.: Eur J Clin Microbiol Infect Dis. 1993 Feb;12(2):114-8. Unique Identifier : AIDSLINE MED/93272753; Kiehn TE; White M; Pursell KJ; Boone N; Tsivitis M; Brown AE; Polsky B; Armstrong D; Infectious Disease Service, Memorial Sloan-Kettering Cancer; Center, New York, New York.; Four cases of infection with Mycobacterium haemophilum occurred at a single hospital in a seven-month period. Only 22 cases have been reported since 1976. All four patients were immunocompromised; two had AIDS and two were the first known recipients of allogeneic bone marrow transplants (BMT) to develop the infection.
Expression of complement receptor 2 (CR2) on HTLV-1-infected lymphocytes and transformed cell lines.: Eur J Immunol. 1993 Jun;23(6):1266-70. Unique Identifier : AIDSLINE MED/93272812; McNearney TA; Ebenbichler CF; Totsch M; Dierich MP; Institut fur Hygiene, Leopold-Franzens Universitat, Innsbruck,; Austria.; The expression of complement receptor 2 (CR2) has been demonstrated in established HTLV-1-transformed cell lines and in 12 studied de novo infected peripheral blood lymphocytes cultures, using 2 HTLV-1 sources. The simultaneous detection of CR2 and HTLV-1 antigens in both co-cultivated and supernatant-infected periphe
The gene loci for immunoglobulin heavy chains in precursor B cell lines from a patient with severe combined immunodeficiency appear able to participate in DNA rearrangement but have a germ-line configuration.: Eur J Immunol. 1993 Jun;23(6):1401-4. Unique Identifier : AIDSLINE MED/93272836; Kamachi Y; Ichihara Y; Tsuge I; Abe T; Torii S; Kurosawa Y; Matsuoka H; Department of Pediatrics, Nagoya University School of Medicine,; Japan.; In a previous study (Immunogenetics 1988. 27:330) with Epstein-Barr virus, we established lines of precursor B cells from bone marrow cells of a patient with severe combined immunodeficiency in whom the numbers of B cells and T cells were markedly reduced. Although based on their surface markers these cell lines appea
Thrombocytopenia (TP) in HIV infection [letter; comment]: Eur J Haematol. 1993 Apr;50(4):239-40. Unique Identifier : AIDSLINE MED/93272938; Landonio G; Cirasino L; Prete A; Nasari A; Imbriani M
Peptide sequencing identifies MSS1, a modulator of HIV Tat-mediated transactivation, as subunit 7 of the 26 S protease.: FEBS Lett. 1993 Jun 1;323(3):276-8. Unique Identifier : AIDSLINE MED/93272970; Dubiel W; Ferrell K; Rechsteiner M; Department of Biochemistry, University of Utah, School of; Medicine, Salt Lake City 84132.; Subunit 7 is an integral component of the human erythrocyte 26 S protease. Peptide sequence analysis reveals that 22 amino acids from the N-terminus of subunit 7 correspond exactly to the N-terminus of MSS1, a modulator of HIV gene expression. Additional internal peptides from subunit 7 obtained by CNBr cleavage also
HIV infection in older patients: when to suspect the unexpected.: Geriatrics. 1993 Jun;48(6):61-4, 69-70. Unique Identifier : AIDSLINE MED/93273252; Wallace JI; Paauw DS; Spach DH; Division of Gerontology and Geriatric Medicine, University of; Washington, Seattle.; The number of AIDS patients over age 60 has risen steadily in the past decade. The number of transfusion-acquired AIDS cases probably has peaked--or will soon peak. Homosexual (or bisexual) behavior remains the predominant risk factor for AIDS until the seventh decade. Disease progression appears to be more rapid in t
Thinking and rethinking AIDS: implications for health policy.: Int J Health Serv. 1993;23(2):323-46. Unique Identifier : AIDSLINE MED/93273573; Fee E; Krieger N; Department of Health Policy and Management, School of Hygiene and; Public Health, Johns Hopkins University, Baltimore, MD 21205.; In the United States , we see three main phases in the construction of the history of AIDS, with each having very different implications for health and social policy. In the first, AIDS was conceived of as an epidemic disease, a gay plague, by analogy to the sudden, devastating epidemic
Complement enhancement of HIV infection is mediated by complement receptors.: Immunopharmacology. 1993 Mar-Apr;25(2):87-93. Unique Identifier : AIDSLINE MED/93273621; Thieblemont N; Delibrias C; Fischer E; Weiss L; Kazatchkine MD; Haeffner-Cavaillon N; INSERM U28, Hopital Broussais, Paris, France.
Pradimicin S, a new pradimicin analog. I. Taxonomy, fermentation and biological activities.: J Antibiot (Tokyo). 1993 Apr;46(4):580-8. Unique Identifier : AIDSLINE MED/93273660; Saitoh K; Tenmyo O; Yamamoto S; Furumai T; Oki T; Bristol-Myers Squibb Research Institute, Tokyo, Japan.; A directed search for antibiotics active in a syncytium formation inhibition assay using a co-culture of HeLa-T4 cells expressing CD4 antigen and BSC-1 cells expressing gp-120 led to the isolation of pradimicin S, a new member of the pradimicin family. The producing strain (AA0851) was characterized as a new species o
The hypertriglyceridemia of acquired immunodeficiency syndrome is associated with an increased prevalence of low density lipoprotein subclass pattern B.: J Clin Endocrinol Metab. 1993 Jun;76(6):1423-7. Unique Identifier : AIDSLINE MED/93273828; Feingold KR; Krauss RM; Pang M; Doerrler W; Jensen P; Grunfeld C; Department of Medicine, University of California, San Francisco.; Plasma low density lipoproteins (LDL) comprise multiple discrete subclasses, differing in size, density, and chemical composition. Gradient gel electrophoresis of LDL has demonstrated three common subclass patterns based on the predominant LDL subclass: large LDL, designated subclass pattern A; small LDL particles, de
Pituitary volume in men with concurrent heroin and cocaine dependence.: J Clin Endocrinol Metab. 1993 Jun;76(6):1529-32. Unique Identifier : AIDSLINE MED/93273846; Teoh SK; Mendelson JH; Woods BT; Mello NK; Hallgring E; Anfinsen P; Douglas A; Mercer G; Endocrine Unit, McLean Hospital-Harvard Medical School, Belmont,; Massachusetts 02178.; Pituitary gland volume was measured in 16 men between the ages of 26-33 with magnetic resonance imaging. Eight male patients had a Diagnostic and Statistical Manual III-Revised, American Psychiatric Association Axis I diagnosis of concurrent opioid and cocaine dependence. The average duration of opioid and cocaine abu
Detection of polymerase chain reaction-amplified human immunodeficiency virus type 1 proviral DNA with a digoxigenin-labeled RNA probe and an enzyme-linked immunoassay.: J Clin Microbiol. 1993 May;31(5):1040-7. Unique Identifier : AIDSLINE MED/93273900; He Y; Coutlee F; Saint-Antoine P; Olivier C; Voyer H; Kessous-Elbaz A; Department of Microbiology and Infectious Diseases, Hopital; Notre-Dame, Montreal, Quebec, Canada.; An enzyme-linked immunoassay (EIA) combined with a solution hybridization (SH) reaction was devised to detect human immunodeficiency virus type 1 (HIV-1) provirus amplified by the polymerase chain reaction (PCR). In this nonisotopic PCR assay, designated PCR-EIASH, a fragment of the HIV-1 gag gene from peripheral bloo
Anticandidal activity and interleukin-1 beta and interleukin-6 production by polymorphonuclear leukocytes are preserved in subjects with AIDS.: J Clin Microbiol. 1993 May;31(5):1354-7. Unique Identifier : AIDSLINE MED/93273960; Cassone A; Palma C; Djeu JY; Aiuti F; Quinti I; Laboratory of Bacteriology and Medical Mycology, Istituto; Superiore di Sanita, Rome, Italy.; Polymorphonuclear granulocytes (PMN; or neutrophils) from uninfected or human immunodeficiency virus-infected subjects were tested for their ability to inhibit growth of Candida albicans and produce interleukin-1 beta (IL-1 beta) and IL-6 in vitro. It was seen that PMN from AIDS (Centers for Disease Control stage IV)
Direct polymerase chain reaction for detection of human immunodeficiency virus in blood spot residues on filter paper after elution of antibodies: an adjunct to serological surveys for estimating vertical transmission rates among human immunodeficiency virus antibody-positive newborns.: J Clin Microbiol. 1993 May;31(5):1364-7. Unique Identifier : AIDSLINE MED/93273963; Yourno J; Virology Laboratory, New York State Department of Health,; Wadsworth Center for Laboratories and Research, Albany; 12201-0509.; Blood spot residues on filter paper circles from which antibodies have been eluted remain suitable for follow-up polymerase chain reaction to detect human immunodeficiency virus (HIV) provirus. A method has been developed for specimen processing and nested polymerase chain reaction amplification with a single tube. HI
Evaluation of a 2-minute anti-human immunodeficiency virus (HIV) test using the autologous erythrocyte agglutination technique with populations differing in HIV prevalence.: J Clin Microbiol. 1993 May;31(5):1373-5. Unique Identifier : AIDSLINE MED/93273966; Sirivichayakul S; Phanuphak P; Tanprasert S; Thanomchat S; Uneklabh C; Phutiprawan T; Mungklavirat C; Panjurai Y; Department of Medicine, Faculty of Medicine, Chulalongkorn; University, Bangkok, Thailand.; A total of 1,800 blood specimens (1,000 from healthy blood donors, 300 from patients with sexually transmitted disease, and 500 from intravenous drug users) were simultaneously tested with anti-human immunodeficiency virus enzyme-linked immunosorbent assay (ELISA) kits and a newly developed 2-min test for anti-human i
Mycobacteria in stool specimens: the nonvalue of smears for predicting culture results.: J Clin Microbiol. 1993 May;31(5):1385-7. Unique Identifier : AIDSLINE MED/93273970; Morris A; Reller LB; Salfinger M; Jackson K; Sievers A; Dwyer B; Clinical Microbiology Laboratory, Duke University Medical Center,; Durham, North Carolina.; A previous recommendation suggests that stool be cultured for mycobacteria only if the smear is positive. We have correlated smear and culture results of 2,176 stool specimens submitted for mycobacterial culture. The sensitivity, specificity, and positive and negative predictive values for smears to predict culture re
AIDS: perspective and strategy [see comments]: J Indian Med Assoc. 1993 Feb;91(2):44-5. Unique Identifier : AIDSLINE MED/93274077; Bhattacharya S; Sil J; Department of Medical Microbiology and Parasitology, University; College of Medicine, University of Calcutta.
AIDS and blood transfusion [letter; comment]: J Indian Med Assoc. 1993 Feb;91(2):45. Unique Identifier : AIDSLINE MED/93274078; Dutta RN
Genetic diversity among strains of Mycobacterium avium causing monoclonal and polyclonal bacteremia in patients with AIDS.: J Infect Dis. 1993 Jun;167(6):1384-90. Unique Identifier : AIDSLINE MED/93274097; Arbeit RD; Slutsky A; Barber TW; Maslow JN; Niemczyk S; Falkinham JO 3d; O'Connor GT; von Reyn CF; Research Service, VA Medical Center, Boston, MA 02130.; To define the genetic diversity among Mycobacterium avium isolates from human immunodeficiency virus-infected patients, specimens were cultured prospectively, and isolates obtained from 14 patients (4 with positive blood, stool, and sputum; 6 with positive blood and stool; 3 with positive blood only; and 1 with positi
Molecular investigation of human immunodeficiency virus (HIV) infection in a patient of an HIV-infected surgeon.: J Infect Dis. 1993 Jun;167(6):1411-4. Unique Identifier : AIDSLINE MED/93274102; Holmes EC; Zhang LQ; Simmonds P; Rogers AS; Brown AJ; Centre for HIV Research, University of Edinburgh, United Kingdom.; Recall of patients who had been treated by a human immunodeficiency virus (HIV)-infected surgeon uncovered 1 previously unknown HIV-seropositive person. Nucleotide sequencing of the gag gene and maximum likelihood phylogenetic analysis were used to investigate the relationships among sequences from the surgeon, the pa
Human immunodeficiency virus infection among high-risk seronegative prostitutes in Nairobi.: J Infect Dis. 1993 Jun;167(6):1414-7. Unique Identifier : AIDSLINE MED/93274103; Willerford DM; Bwayo JJ; Hensel M; Emonyi W; Plummer FA; Ngugi EN; Nagelkerke N; Gallatin WM; Kreiss J; Division of Basic Sciences, Fred Hutchinson Cancer Research; Center, Seattle.; To determine the frequency and duration of antibody-negative human immunodeficiency virus (HIV) infection among heterosexually exposed African women, 56 HIV-seronegative female prostitutes in Nairobi were studied. Polymerase chain reaction (PCR) was used to detect HIV DNA in peripheral blood at enrollment, and women w
Immunogenicity of high-titer Edmonston-Zagreb measles vaccine in human immunodeficiency virus-infected children in Kinshasa, Zaire.: J Infect Dis. 1993 Jun;167(6):1418-21. Unique Identifier : AIDSLINE MED/93274104; Cutts FT; Mandala K; St Louis M; Brown C; Mayala B; Zell ER; Deforest A; Kamenga M; Davachi F; Markowitz LE; Division of Immunization, Centers for Disease Control and; Prevention, Atlanta, Georgia.; The response to Edmonston-Zagreb vaccine (titer, 5.4 log10 pfu) was evaluated among children in a study of perinatal transmission of human immunodeficiency virus (HIV) in Kinshasa. Acute postvaccination adverse events were monitored for 49 HIV-infected and 376 non-HIV-infected infants, and measles antibody responses w
Salvage trial of trimetrexate-leucovorin for the treatment of cerebral toxoplasmosis in patients with AIDS.: J Infect Dis. 1993 Jun;167(6):1422-6. Unique Identifier : AIDSLINE MED/93274105; Masur H; Polis MA; Tuazon CU; Ogata-Arakaki D; Kovacs JA; Katz D; Hilt D; Simmons T; Feuerstein I; Lundgren B; et al; National Institutes of Health, Bethesda, MD 20892.; The clinical efficacy of trimetrexate, a dihydrofolate reductase inhibitor with potent in vitro antitoxoplasma activity, was assessed in 9 sulfonamide-intolerant patients with AIDS and biopsy-proven cerebral toxoplasmosis. The 9 patients were treated for 28-149 days with trimetrexate (30-280 mg/m2/day) plus leucovorin
Involvement of interferon-gamma and tumor necrosis factor-alpha in host defense against Rhodococcus equi.: J Infect Dis. 1993 Jun;167(6):1456-9. Unique Identifier : AIDSLINE MED/93274113; Nordmann P; Ronco E; Guenounou M; Department of Microbiology, Paris-Ouest Medical School, Paris V; University, Garches, France.; Rhodococcus equi is a facultative, intracellular, gram-positive coccobacillus increasingly reported as an opportunistic pathogen in AIDS patients. In vitro, splenic cells of noninfected euthymic mice produced tumor necrosis factor-alpha (TNF alpha) in greater amounts when incubated with live R. equi rather than with k
Clofazimine as prophylaxis for disseminated Mycobacterium avium complex infection in AIDS.: J Infect Dis. 1993 Jun;167(6):1459-63. Unique Identifier : AIDSLINE MED/93274114; Abrams DI; Mitchell TF; Child CC; Shiboski SC; Brosgart CL; Mass MM; San Francisco General Hospital, CA.; A randomized, prospective, open-label, treatment versus no treatment community-based clinical trial was conducted to evaluate the safety and efficacy of clofazimine as prophylaxis for disseminated Mycobacterium avium complex (MAC) infection in patients with human immunodeficiency virus (HIV) disease. Subjects were 110
Use of the human immunodeficiency virus virion as a universal standard for viral RNA quantitation by reverse transcription-linked polymerase chain reaction [letter]: J Infect Dis. 1993 Jun;167(6):1498-9. Unique Identifier : AIDSLINE MED/93274121; Lu W; Andrieu JM
Reversal of apparent AIDS dementia complex following treatment with vitamin B12.: J Intern Med. 1993 Jun;233(6):495-7. Unique Identifier : AIDSLINE MED/93274249; Herzlich BC; Schiano TD; Department of Medicine, Maimonides Medical Center, Brooklyn, New; York.; The human immunodeficiency virus (HIV)-associated dementia complex is characterized by difficulties in concentration and memory followed by apathy, social withdrawal and motor dysfunction. Decreased serum vitamin B12 levels occur in up to 20% of patients with acquired immune defici
Antisocial personality disorder among drug abusers. Relations to other personality diagnoses and the five-factor model of personality.: J Nerv Ment Dis. 1993 May;181(5):313-9. Unique Identifier : AIDSLINE MED/93274279; Brooner RK; Herbst JH; Schmidt CW; Bigelow GE; Costa PT Jr; Johns Hopkins School of Medicine, Baltimore, Maryland.; Antisocial personality disorder among drug abusers has been associated with poor drug abuse treatment outcome and greater human immunodeficiency virus infection risk compared with drug abusers without the disorder. Despite this, less is known about the personality trait dimensions of antisocial drug abusers, or about
Design of a prospective study of the pulmonary complications of human immunodeficiency virus infection. The Pulmonary Complications of HIV Infection Study Group.: J Clin Epidemiol. 1993 Jun;46(6):497-507. Unique Identifier : AIDSLINE MED/93274311; Because no studies have systematically described the pulmonary complications associated with early stages of infection with the human immunodeficiency virus (HIV), the National Heart, Lung and Blood Institute and the National Institute of Allergy and Infectious Diseases jointly initiated a prospective cohort study in
Randomized study of two doses of didanosine in children infected with human immunodeficiency virus.: J Pediatr. 1993 Jun;122(6):966-73. Unique Identifier : AIDSLINE MED/93274475; Blanche S; Calvez T; Rouzioux C; Ortigao MB; Taburet AM; Ferroni A; Debre M; Wintrebert F; Singlas E; Costagliola D; et al; Unite d'Immunologie et d'Hematologie pediatrique, INSERM U132,; Hopital Necker Enfants Malades, France.; 2 3 -Dideoxyinosine (didanosine) is a nucleoside analog active in vitro against human immunodeficiency virus. Few data are available regarding its use for the treatment of children. In a single-center, randomized, open-label trial, we compared two dosages of didanosine (120 vs 270 mg/m2 per day) for at least 6 months
Cytokines and lymphocyte function in children infected with human immunodeficiency virus [letter; comment]: J Pediatr. 1993 Jun;122(6):989-90. Unique Identifier : AIDSLINE MED/93274480; Rautonen J; Rautonen N
Prevalence of Cryptosporidium sp. and Isospora belli among AIDS patients attending Santos Reference Center for AIDS, Sao Paulo, Brazil.: J Parasitol. 1993 Jun;79(3):454-6. Unique Identifier : AIDSLINE MED/93274504; Sauda FC; Zamarioli LA; Ebner Filho W; Mello L de B; Instituto Adolfo Lutz, Santos-S.P., Brazil.; From March 1991 to February 1992, 276 stool samples from 131 patients with the acquired immunodeficiency syndrome (AIDS) (average, 2.1 samples per patient) and stool samples from 81 presumed immunocompetent individuals were studied for the prevalence of Cryptosporidium sp. and Isospora belli. The techniques employed w
Fungal infections of the genitourinary system.: J Urol. 1993 Jun;149(6):1377-88. Unique Identifier : AIDSLINE MED/93274712; Wise GJ; Silver DA; Division of Urology, Maimonides Medical Center, Brooklyn, New; York.
HIV infection as leading cause of death among young adults in US cities and states [published erratum appears in JAMA 1993 Aug 11;270(6):710] [see comments]: JAMA. 1993 Jun 16;269(23):2991-4. Unique Identifier : AIDSLINE MED/93274794; Selik RM; Chu SY; Buehler JW; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, GA 30333.; OBJECTIVE--To describe the extent to which human immunodeficiency virus (HIV) infection has become the leading cause of death among young adults (25 to 44 years of age) in US states and cities of at least 100,000 population. DESIGN--Analysis of underlying causes of death using national vital statistics for 1990 by sta
The completeness of AIDS case reporting in New York City [see comments]: JAMA. 1993 Jun 16;269(23):2995-3001. Unique Identifier : AIDSLINE MED/93274795; Greenberg AE; Hindin R; Nicholas AG; Bryan EL; Thomas PA; Office of AIDS Surveillance, New York City, Department of Health,; NY 10013.; OBJECTIVE--To assess the completeness of acquired immunodeficiency syndrome (AIDS) case reporting in New York City (NYC), and to determine whether the completeness of reporting differs in various populations. DESIGN--Retrospective record review of hospital laboratory logs, death certificates, hospital discharge record
Rising HIV-related mortality in young Americans [editorial; comment]: JAMA. 1993 Jun 16;269(23):3034-5. Unique Identifier : AIDSLINE MED/93274801; Vermund SH
A study on the clinical effect and immunological mechanism in the treatment of Hashimoto's thyroiditis by moxibustion.: J Tradit Chin Med. 1993 Mar;13(1):14-8. Unique Identifier : AIDSLINE MED/93274912; Hu G; Chen H; Hou Y; He J; Cheng Z; Wang R; Shanghai Research Institute of Acupuncture & Meridian.; 71 cases of Hashimoto s thyroiditis were treated by moxibustion and their immune function and thyroid function were observed. It was found that moxibustion was able to reduce the thyroid antibodies in the peripheral blood of the patients with hypothyroidism and to recover their thyroid function. It was also found that
Stimulation of HTLV-I expression by subtoxic dose of 3-methylcholanthrene.: Leuk Res. 1993 May;17(5):429-35. Unique Identifier : AIDSLINE MED/93274932; Feldman G; Aboud M; Department of Microbiology and Immunology, Faculty of Health; Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel.; In vivo infection by HTLV-I is characterized by the lack of virus expression in the host s infected cells and in most cases it is clinically inapparent. The present study shows that exposure of HTLV-I-infected human T-cells to a maximal non-toxic dose of 3-MC remarkably enhances virus expression. This stimulatory effe
Serum levels of a negative regulator of cell proliferation (AcSDKP) are increased in certain human haemopathies.: Leukemia. 1993 Jun;7(6):808-12. Unique Identifier : AIDSLINE MED/93274942; Liozon E; Pradelles P; Venot J; Rigaud M; Cransac M; Bordessoule D; Frindel E; CJF INSERM, Limoges, France.; One of the first known effects of the endogenous peptide N-acetyl-Ser-Asp-Lys-Pro (AcSDKP) is to inhibit entry into DNA synthesis of pluripotent haematopoietic stem cells (CFU-S) in mice. A specific anti-AcSDKP polyclonal antibody allows the level of the tetrapeptide by to be determined by enzyme immunoassay with good
[Discrepancies in the statistics of HIV-positive persons should be corrected (letter; comment)]: Lakartidningen. 1993 May 12;90(19):1839. Unique Identifier : AIDSLINE MED/93274986; Hogman CF; Messeter L
[HIV screening of pregnant women and blood donors]: Lakartidningen. 1993 May 12;90(19):1851. Unique Identifier : AIDSLINE MED/93274992
[A case report. Psychotic symptoms in a patient with HIV-1 infection]: Lakartidningen. 1993 May 19;90(20):1961-2. Unique Identifier : AIDSLINE MED/93275013; Alexius B; Jarl M; Jonsson P; Psykiatriska klinikerna, Danderyds sjukhus.
Looking for a 'superantigen' in AIDS: a possible role for Mycoplasma?: Med Hypotheses. 1993 Mar;40(3):146-53. Unique Identifier : AIDSLINE MED/93275267; Bisset LR; Department of Internal Medicine, University Hospital, Zurich,; Switzerland.; The extensive effort made to comprehend the complex immunopathology of human immunodeficiency virus (HIV) infection has resulted in research groups focusing attention on hypotheses as disparate as the possible superantigen potential of HIV and the possible requirement for a Mycoplasma cofactor . Utilizing the recen
Recommended infection-control practices for dentistry, 1993. Centers for Disease Control and Prevention.: MMWR Morb Mortal Wkly Rep. 1993 May 28;42(RR-8):1-12. Unique Identifier : AIDSLINE MED/93275287; This document updates previously published CDC recommendations for infection-control practices in dentistry to reflect new data, materials, technology, and equipment. When implemented, these recommendations should reduce the risk of disease transmission in the dental environment, from patient to dental health-care wor
Selective screening to augment syphilis case-finding--Dallas, 1991.: MMWR Morb Mortal Wkly Rep. 1993 Jun 11;42(22):424-7. Unique Identifier : AIDSLINE MED/93275289; Increased use of crack cocaine and the exchange of sex for drugs have been major contributors to the increased occurrence of syphilis in U.S. urban, minority populations (1-3). Because many persons who use drugs do not voluntarily seek health care (1,4), and because their sex partners are often difficult to locate (5)
Outbreak of multidrug-resistant tuberculosis at a hospital--New York City, 1991.: MMWR Morb Mortal Wkly Rep. 1993 Jun 11;42(22):427, 433-4. Unique Identifier : AIDSLINE MED/93275290; From January 1991 through July 1992, multidrug-resistant (i.e., resistant to at least isoniazid [INH] and rifampin [RIF]) Mycobacterium tuberculosis (MDR-TB) was isolated from 43 (22%) of 198 patients with newly diagnosed TB at a New York City hospital. This report summarizes an epidemiologic investigation by the hosp
HIV prevention through case management for HIV-infected persons--selected sites, United States, 1989-1992.: MMWR Morb Mortal Wkly Rep. 1993 Jun 18;42(23):448-9, 455-6. Unique Identifier : AIDSLINE MED/93275295; Transmission of human immunodeficiency virus (HIV) infection can be prevented through HIV-prevention case management--a one-on-one client service specifically designed to assist HIV-infected persons in receiving services that will prevent or reduce behaviors that result in further spread of the virus, delay the onset
A population-based assessment of invasive disease due to group B Streptococcus in nonpregnant adults [see comments]: N Engl J Med. 1993 Jun 24;328(25):1807-11. Unique Identifier : AIDSLINE MED/93275376; Farley MM; Harvey RC; Stull T; Smith JD; Schuchat A; Wenger JD; Stephens DS; Department of Medicine, Emory University School of Medicine,; Atlanta, GA.; BACKGROUND. Group B streptococci (Streptococcus agalactiae) are a major cause of meningitis and septicemia in neonates and pregnant women, but the importance of group B streptococcal disease in nonpregnant adults has not been clearly defined. METHODS. We conducted a prospective surveillance of the pathogens responsibl
Brief report: myeloma-associated paraprotein directed against the HIV-1 p24 antigen in an HIV-1-seropositive patient.: N Engl J Med. 1993 Jun 24;328(25):1817-9. Unique Identifier : AIDSLINE MED/93275378; Konrad RJ; Kricka LJ; Goodman DB; Goldman J; Silberstein LE; Department of Pathology and Laboratory Medicine, University of; Pennsylvania School of Medicine, Philadelphia 19104-6082.
Conference unwanted [editorial; comment]: Nature. 1993 Jun 3;363(6428):382. Unique Identifier : AIDSLINE MED/93275398
AIDS activists says basic research is underfunded [news]: Nature. 1993 Jun 3;363(6428):388. Unique Identifier : AIDSLINE MED/93275403; Macilwain C
Rumoured good news raises share price of vaccine company [news]: Nature. 1993 Jun 3;363(6428):388. Unique Identifier : AIDSLINE MED/93275404; Macilwain C
AIDS: striking the happy media.: Nature. 1993 Jun 3;363(6428):391-2. Unique Identifier : AIDSLINE MED/93275405; Moore J; Aaron Diamond AIDS Research Center, New York, New York 10016.; The past year has seen many controversies about AIDS research and researchers. What productive events have occurred, and what is likely to happen in the next year?
AIDS: trends, predictions, controversy.: Nature. 1993 Jun 3;363(6428):393-4. Unique Identifier : AIDSLINE MED/93275406; Anderson R; Biology Department, Imperial College of Science, Technology and; Medicine, London, UK.; One of the persistent controversies that surfaces in the media about AIDS is whether the heterosexual population is at risk. The latest projections provide an emphatic affirmative.
The origin of HIV-1 isolate HTLV-IIIB.: Nature. 1993 Jun 3;363(6428):466-9. Unique Identifier : AIDSLINE GENBANK/M96499; Chang SY; Bowman BH; Weiss JB; Garcia RE; White TJ; Roche Molecular Systems Inc., Alameda, California 94501.; The striking similarity between the first two human immunodeficiency virus type 1 (HIV-1) isolates Lai/LAV (formerly LAV, isolated at the Pasteur Institute) and Lai/IIIB (formerly HTLV-IIIB, reported to be isolated from a pooled culture at the Laboratory of Tumor Cell Biology (LTCB) of the National Cancer Institute) p
Use the language of caring.: Nurs Health Care. 1993 Apr;14(4):174. Unique Identifier : AIDSLINE MED/93275561; Fedor MA
Helicobacter pylori in children with acquired immunodeficiency syndrome [letter]: Pediatrics. 1993 Jun;91(6):1217. Unique Identifier : AIDSLINE MED/93275720; Blecker U; Keymolen K; Souayah H; Levy J; Vandenplas Y
A method to increase the cumulative cleavage efficiency of ribozymes: thermal cycling.: Nucleic Acids Res. 1993 May 11;21(9):2273-4. Unique Identifier : AIDSLINE MED/93275775; Dropulic B; Lin NH; Jeang KT; Laboratory of Molecular Microbiology, National Institute of; Allergy and Infectious Diseases, National Institutes of Health,; Bethesda, MD 20892.
[Listeria monocytogenes in patients with human immunodeficiency virus infection. 2 cases (letter)]: Presse Med. 1993 Feb 27;22(7):315. Unique Identifier : AIDSLINE MED/93275850; Poizot-Martin I; Charbonnier A; Dhiver C; Gastaut JA
[Febrile pancytopenia in AIDS. Value of bone marrow cell count in the early diagnosis of opportunistic infections (letter)]: Presse Med. 1993 Mar 6;22(8):387. Unique Identifier : AIDSLINE MED/93275853; Castanet J; Taillan B; Heudier P; Marty P; Garnier G; Fuzibet JG; Dujardin P
Delta hepatitis and infection in North America.: Prog Clin Biol Res. 1993;382:243-50. Unique Identifier : AIDSLINE MED/93275915; Alter MJ; Hadler SC; Hepatitis Branch, Centers for Disease Control, Atlanta, GA 30333.
Seroprevalence of HDV and HIV in two populations at risk for infection with HBV in Spain.: Prog Clin Biol Res. 1993;382:267-75. Unique Identifier : AIDSLINE MED/93275918; Herrera A; Ortega E; Soler JJ; Garcia S; Rodriguez C; Del Romero J; University of Valencia, University General Hospital of Valencia,; Spain.; We have studied 1765 patients attending our clinic during 1991, with the aim of determining the prevalence of HDV and HIV infection in our country in two populations at risk for parenteral and sexual HBV transmission. A second objective was to determine whether or not HBV-HIV co-infection was associated with a greater
Polymerase chain reaction-based detection of hepatitis D virus RNA in patients infected with human immunodeficiency virus.: Prog Clin Biol Res. 1993;382:329-35. Unique Identifier : AIDSLINE MED/93275927; Lecot C; Jeantils V; Ovaguimian L; Krivitzky A; Brechot C; Deny P; CHU Avicenne, Paris, France.; We used the polymerase chain reaction (PCR) to detect hepatitis D (HD) viremia in patients infected with the human immunodeficiency virus (HIV). Nineteen (9%) of 206 such patients were prospectively found to be infected by HDV. Thirty-one anti-HIV-positive patients were studied by means of PCR and the results were ana
Nongonococcal bacterial arthritis.: Rheum Dis Clin North Am. 1993 May;19(2):311-31. Unique Identifier : AIDSLINE MED/93276009; Mikhail IS; Alarcon GS; Division of Clinical Immunology and Rheumatolog, University of; Alabama, Birmingham.; The most salient features of nongonococcal bacterial arthritis are reviewed. Factors such as life expectancy, prosthetic joints, arthroscopies, the spread of the AIDS epidemic, and of methicillin-resistant Staphylococcus aureus as modifiers of the course of these arthritides are discussed.
Syphilitic arthritis and osteitis.: Rheum Dis Clin North Am. 1993 May;19(2):379-98. Unique Identifier : AIDSLINE MED/93276013; Reginato AJ; Department of Medicine, University of Medicine and Dentistry of; New Jersey/Robert Wood Johnson Medical School, Camden.; Syphilis again has become a significant clinical problem and clinicians must reacquaint themselves with the classic as well as the changing clinical manifestations, new diagnostic methods, interaction with HIV infections, and outcomes of therapy. Musculoskeletal manifestations can be associated with congenital, second
Human immunodeficiency virus (HIV) infection and arthritis [published erratum appears in Rheum Dis Clin North Am 1993 Aug;19(3):ix]: Rheum Dis Clin North Am. 1993 May;19(2):477-88. Unique Identifier : AIDSLINE MED/93276018; Calabrese LH; Department of Rheumatic and Immunologic Diseases, Cleveland; Clinic Foundation, Ohio.; A variety of inflammatory arthritic conditions are observed in the setting of HIV infection. The epidemiology of these disorders is a point of current controversy, although it appears that several unique syndromes are clinically associated. The pathogenesis of these disorders remains unclear, but we hope that further
Rheumatic manifestation of human leukemia virus infection.: Rheum Dis Clin North Am. 1993 May;19(2):489-503. Unique Identifier : AIDSLINE MED/93276019; Nishioka K; Nakajima T; Hasunuma T; Sato K; Rheumatology Division, St. Marianna University, Kawasaki, Japan.; Rheumatic disorders associated with retroviruses are described in this article. A recent study of human T-cell leukemia virus type-I (HTLV-I) revealed that it appeared to be associated with the pathogenesis of several immune disorders such as myelopathy, broncho-pneumopathy, Sjogren s syndrome, and arthropathy. HTLV-I
[Cerebral imaging and AIDS]: Rev Prat. 1993 Feb 1;43(3):339-45. Unique Identifier : AIDSLINE MED/93276242; Martin-Duverneuil N; Sola-Martinez MT; Departement de neuroradiologie diagnostique et therapeutique,; hopital de la Salpetriere, Paris.; Cerebral lesions in AIDS patients are characterized by a great variety of pathologies, except for HIV infection itself, related to the immunodeficiency context. Due to their frequent association, the interest of imagery (CT and MRI) remains essential today (despite of the underestimation of the lesions due to the weak
Relation of phenotype evolution of HIV-1 to envelope V2 configuration [see comments]: Science. 1993 Jun 4;260(5113):1513-6. Unique Identifier : AIDSLINE MED/93276273; Groenink M; Fouchier RA; Broersen S; Baker CH; Koot M; van't Wout AB; Huisman HG; Miedema F; Tersmette M; Schuitemaker H; Department of Clinical Viro-Immunology, Central Laboratory of the; Netherlands Red Cross Blood Transfusion Service, Amsterdam.; Biological variability of human immunodeficiency virus type-1 (HIV-1) is involved in the pathogenesis of acquired immunodeficiency syndrome (AIDS). Syncytium-inducing (SI) HIV-1 variants emerge in 50 percent of infected individuals during infection, preceding accelerated CD4+ T cell loss and rapid progression to AIDS.
Canadian blood inquiry [news]: Science. 1993 Jun 11;260(5114):1586. Unique Identifier : AIDSLINE MED/93276282
The effect of video interventions on improving knowledge and treatment compliance in the sexually transmitted disease clinic setting. Lesson for HIV health education.: Sex Transm Dis. 1993 Mar-Apr;20(2):70-6. Unique Identifier : AIDSLINE MED/93276361; Healton CG; Messeri P; Division of Socio-Medical Sciences, Columbia University, School; of Public Health, New York, NY 10032.; Eight intervention studies investigating patient education and treatment adherence in the sexually transmitted disease (STD) clinic setting are reviewed. Across the eight studies selected for analysis, meta-analytic procedures were applied to compare the impact of educational and prevention approaches. The effect of v
Use of condoms by heterosexually active drug abusers before and after AIDS education.: Sex Transm Dis. 1993 Mar-Apr;20(2):81-8. Unique Identifier : AIDSLINE MED/93276363; McCusker J; Stoddard AM; Zapka JG; Zorn M; School of Public Health, University of Massachusetts, Amherst; 01003.; This study identified variables associated with increased condom use among drug abusers in a randomized trial of three AIDS educational programs in a short-term inpatient detoxification program. Participants (n = 301) completed baseline and follow-up interviews and were heterosexually active on both occasions. At base
Homologous superinfection of both producer and nonproducer HIV-infected cells is blocked at a late retrotranscription step.: Virology. 1993 Jun;194(2):441-52. Unique Identifier : AIDSLINE GENBANK/K03455; Taddeo B; Federico M; Titti F; Rossi GB; Verani P; Laboratory of Virology, Istituto Superiore di Sanita, Rome,; Italy.; An HUT-78 cell clone (F12) chronically infected by a nonproducer HIV-1 variant (Federico et al., (1989) AIDS Res. Hum. Retroviruses 5, 385-396) is fully resistant to superinfection with HIV-1 or HIV-2. We demonstrate that, in spite of the down-regulation of CD4 receptors, superinfecting-HIV-1 and -HIV-2 cross the F12
Assembly of the matrix protein of simian immunodeficiency virus into virus-like particles.: Virology. 1993 Jun;194(2):548-56. Unique Identifier : AIDSLINE MED/93276541; Gonzalez SA; Affranchino JL; Gelderblom HR; Burny A; Department of Molecular Biology, University of Brussels (ULB),; Belgium.; To obtain a better understanding of the processes of assembly and morphogenesis of simian immunodeficiency virus (SIV), recombinant vaccinia viruses containing regions of the gag-pol open reading frame were constructed and their intracellular expression as well as the ability of the Gag polypeptides to be released int
Conformational perturbation of the envelope glycoprotein gp120 of human immunodeficiency virus type 1 by soluble CD4 and the lectin succinyl Con A.: Virology. 1993 Jun;194(2):833-7. Unique Identifier : AIDSLINE MED/93276574; Pal R; DeVico A; Rittenhouse S; Sarngadharan MG; Advanced BioScience Laboratories, Incorporated, Department of; Cell Biology, Kensington, Maryland 20895.; We have studied perturbation of the gp120/gp41 envelope complex of HIV-1 in the presence of the mannose-specific lectin succinyl Con A (SC) and compared the effect with that observed in the presence of soluble CD4 (sCD4). SC did not inhibit the binding of gp120 to CD4. Both sCD4 and SC inhibited syncytium formation in
Mutations in the protease gene of human immunodeficiency virus type 1 affect release and stability of virus particles.: Virology. 1993 Jun;194(2):843-50. Unique Identifier : AIDSLINE MED/93276576; Park J; Morrow CD; Department of Microbiology, University of Alabama, Birmingham; 35294.; The expression of the pol gene of human immunodeficiency virus type 1 (HIV-1) occurs by a ribosomal frameshift between the gag and the pol genes. The Gag-Pol polyprotein is produced at levels of 5 to 10% of that of the Gag protein, and is incorporated into virions to provide the viral protease, reverse transcriptase,
The majority of simian immunodeficiency virus/mne circle junctions result from ligation of unintegrated viral DNA ends that are aberrant for integration.: Virology. 1993 Jun;194(2):851-4. Unique Identifier : AIDSLINE MED/93276577; Randolph CA; Champoux JJ; Department of Microbiology, School of Medicine, University of; Washington, Seattle 98195.; SIV/Mne circle junctions were amplified by the polymerase chain reaction (PCR) and cloned in a bacterial plasmid. Sequence analysis of clones isolated from 11 independent PCRs reveals that the start site for plus DNA synthesis is 5 ACTG. . ., and thus an asymmetric cleavage must occur during viral integration. In add
A molecular clone of HIV-1 tropic and cytopathic for human and chimpanzee lymphocytes.: Virology. 1993 Jun;194(2):858-64. Unique Identifier : AIDSLINE GENBANK/L02317; Ghosh SK; Fultz PN; Keddie E; Saag MS; Sharp PM; Hahn BH; Shaw GM; Department of Medicine, University of Alabama, Birmingham 35294.; Previous studies of HIV-1 replication in chimpanzee lymphocytes have been limited to a small number of virus isolates which generally replicated poorly and without cytopathic effect. Here, we describe an HIV-1 provirus (SG3), cloned as a single proviral unit, which replicates more efficiently in chimpanzee than in hum
Fatal metastatic calcification in a patient with HTLV-1-associated lymphoma.: West Indian Med J. 1993 Mar;42(1):37-9. Unique Identifier : AIDSLINE MED/93276629; Daisley H; Charles WP; Department of Pathology, U.W.I., St. Augustine, Trinidad.; Metastatic calcification of the heart, lungs and kidneys is described in a 42-year-old male who had an HTLV-1-associated lymphoma. This fatal complication of HTLV-1-associated lymphoma has been infrequently reported, and the case in question is the first to be recorded in the Caribbean, where HTLV-1 is common. Aggress
Polymerase chain reaction for diagnosis of infectious diseases.: Acta Paediatr Jpn. 1993 Apr;35(2):89-97. Unique Identifier : AIDSLINE MED/93276696; Narita M; Department of Pediatrics, Hokkaido University School of Medicine,; Sapporo, Japan.; The polymerase chain reaction (PCR) has been utilized and demonstrated to be useful for detecting minute amounts of a wide variety of infectious agents. In such studies, one must keep in mind that the most appropriate conditions for amplification vary with organisms of interest. In this study, PCR was used as a rapid
Treatment of AIDS and HIV-related conditions--1993.: J Am Board Fam Pract. 1993 May-Jun;6(3):297-315. Unique Identifier : AIDSLINE MED/93276724; Goldschmidt RH; Dong BJ; Family Practice Residency Program, San Francisco General; Hospital, CA 94110.
Clostridium difficile infection is a treatable cause of diarrhea in patients with advanced human immunodeficiency virus infection: a study of seven consecutive patients admitted from 1986 to 1992 to a university teaching hospital.: Am J Gastroenterol. 1993 Jun;88(6):891-7. Unique Identifier : AIDSLINE MED/93276815; Cappell MS; Philogene C; Division of Gastroenterology, UMDNJ-Robert Wood Johnson, Medical; School, New Brunswick.; Of 427 human immunodeficiency virus-seropositive patients admitted to the Robert Wood Johnson University Hospital from January 1986 through August 1992, seven had Clostridium difficile enteric infection documented by the presence of cytotoxin B in the stool, without other enteric infection. All seven patients had AIDS
Cost effectiveness of noninvasive oxygen saturation measurement during exercise for the diagnosis of Pneumocystis carinii pneumonia.: Am Rev Respir Dis. 1993 Jun;147(6 Pt 1):1360-3. Unique Identifier : AIDSLINE MED/93276998; Chouaid C; Maillard D; Housset B; Febvre M; Zaoui D; Lebeau B; Pneumology Service, Hopital Saint Antoine, Paris.; We assessed (1) the sensitivity and specificity of exercise oxygen saturation measurement (EOS) for the diagnosis of Pneumocystis carinii pneumonia (PCP); and (2) the cost of introducing this indirect diagnostic test compared with that of standard diagnostic strategies for PCP. In a prospective study, 85 HIV-infected
Physiologic responses and distribution of aerosolized surfactant (Survanta) in a nonuniform pattern of lung injury.: Am Rev Respir Dis. 1993 Jun;147(6 Pt 1):1364-70. Unique Identifier : AIDSLINE MED/93276999; Lewis JF; Ikegami M; Jobe AH; Absolom D; Department of Medicine, St. Joseph's Health Centre, London,; Ontario, Canada.; The underlying pattern of lung injury in patients with the adult respiratory distress syndrome (ARDS) may be nonuniform. The purpose of this study was to document whether a nonuniform pattern of lung injury influences treatment responses to aerosolized exogenous surfactant. Adult sheep underwent either total lung lava
[HIV infection in infancy and childhood. Report of the second Spanish multicenter study (1991). Expert Committee on Pediatric AIDS]: An Esp Pediatr. 1993 May;38(5):469-70. Unique Identifier : AIDSLINE MED/93277061
[Autoimmunity and AIDS (editorial)]: Ann Med Interne (Paris). 1993;144(1):43-4. Unique Identifier : AIDSLINE MED/93277070; Youinou P; Garre M; Mottier D; Lamour A; Dueymes M
The current status of AIDS in Asia [editorial]: Ann Med Interne (Paris). 1993;144(1):45-6. Unique Identifier : AIDSLINE MED/93277071; Phanuphak P
[Human immunodeficiency virus infection and the thyroid tests]: Ann Med Interne (Paris). 1993;144(1):47-50. Unique Identifier : AIDSLINE MED/93277072; Lambert M; De Nayer P; Service de Medecine Interne Generale, Cliniques Universitaires; Saint-Luc, Bruxelles, Belgique.
[Provisory conclusions apropos of the prevention trials of opportunistic infections supported by ANRS (National Research Agency)]: Ann Med Interne (Paris). 1993;144(1):51. Unique Identifier : AIDSLINE MED/93277073; Dormont J
[Results of the final analysis of the PRIO trial]: Ann Med Interne (Paris). 1993;144(1):52-3. Unique Identifier : AIDSLINE MED/93277074; Girard PM; Landman R
[Consensual proposals for the treatment of toxoplasmosis in patients with human immunodeficiency virus infection]: Ann Med Interne (Paris). 1993;144(1):53-6. Unique Identifier : AIDSLINE MED/93277075; Leport C; Ambroise-Thomas P; Chene G; Katlama C; Raffi F; Vilde JL
[Update on consensual proposals (1993 February). Role of cotrimoxazole in the primary prevention of toxoplasmosis in patients with HIV infection]: Ann Med Interne (Paris). 1993;144(1):56-7. Unique Identifier : AIDSLINE MED/93277076; Leport C; Ambroise-Thomas P; Chene G; Derouin F; Katlama C; Raffi F; Vilde JL
[Viral surrogate markers: their value in the therapeutic follow-up]: Ann Med Interne (Paris). 1993;144(1):58-60. Unique Identifier : AIDSLINE MED/93277077; Brun-Vezinet F; Laboratoire de Virologie, Hopital Bichat-Claude Bernard, Paris.
[Pulmonary pneumocystosis and renal transplantation: influence of the AIDS epidemic (letter)]: Ann Med Interne (Paris). 1993;144(1):61. Unique Identifier : AIDSLINE MED/93277078; Flament M; Couderc LJ; Aubert P; Epardeau B; Guedon J; Caubarrere I
[Clindamycin and primaquine in the treatment of pulmonary pneumocystosis in a HIV-positive female patient (letter)]: Ann Med Interne (Paris). 1993;144(1):61-3. Unique Identifier : AIDSLINE MED/93277079; Zouiten F; Bouslama K; Gastli M; Tiouiri H; Battikh R; Ben Salem N; Ben Chaabane T; Chaker E; Ben Rachid MS; Zribi A
[Demodex folliculitis: a cause of pruritus in human immunodeficiency virus infection (letter)]: Ann Med Interne (Paris). 1993;144(1):63-4. Unique Identifier : AIDSLINE MED/93277080; de Jaureguiberry JP; Carsuzaa F; Pierre C; Arnoux D; Jaubert D
[Primary lymphoma of the central nervous system disclosed in the spinal cord site in a patient with human immunodeficiency virus infection (letter)]: Ann Med Interne (Paris). 1993;144(1):64-6. Unique Identifier : AIDSLINE MED/93277081; Herida M; Khuong MA; De Broucker T; Henin D; Mechali D
Containment of AIDS in Singapore--legal and policy implications.: Ann Acad Med Singapore. 1993 Jan;22(1):111-8. Unique Identifier : AIDSLINE MED/93277102; Iyer TK; Law Faculty, National University of Singapore.; Law has an important supportive role in containing the spread of AIDS. This essay hopes to show the ways in which law can help and ways in which it cannot. There is a discussion of the relevant laws of Singapore including the Infectious Diseases (Amendment) Act, 1992. Areas wher
Human immunodeficiency virus infection confronts the law, ethics and society.: Ann Acad Med Singapore. 1993 Jan;22(1):69-85. Unique Identifier : AIDSLINE MED/93277116; Hirsh HL; George Washington University, Washington DC.; The full panorama of the AIDS problem is filled with contradictions. There are those who consider the AIDS sufferers--primarily gays and intravenous drug abusers--as the bad group. Yet, there are also innocent victims: recipients of blood and blood products and the unknowing sex partners. Regardless of the circumstanc
Dizygotic twins discordant for HIV and hepatitis C virus.: Arch Dis Child. 1993 Apr;68(4):507. Unique Identifier : AIDSLINE MED/93277159; Barlow KM; Mok JY; Regional Infectious Diseases Unit, City Hospital, Edinburgh.; Twin girls were born at 37 weeks gestation to a mother infected by HIV and hepatitis C virus. Twin 1 had symptomatic HIV infection by 9 months but was negative for hepatitis C virus antibody and RNA. Twin 2 became HIV antibody negative by 15 months but was positive for antihepatitis C virus and RNA.
Continuous infusion of zidovudine in HIV related thrombocytopenia [letter]: Arch Dis Child. 1993 Apr;68(4):525-6. Unique Identifier : AIDSLINE MED/93277167; Rahimy C; Jacqz-Aigrain E; Broyard A; Brun-Vezinet F; Vilmer E
The lupus anticoagulant. High incidence of 'negative' mixing studies in a human immunodeficiency virus-positive population [see comments]: Arch Pathol Lab Med. 1993 Jun;117(6):595-601. Unique Identifier : AIDSLINE MED/93277316; Clyne LP; Yen Y; Kriz NS; Breitenstein MG; Department of Clinical Laboratories, Yale-New Haven Hospital, CT.; We identified 100 patients (51 males and 49 females) as having the lupus anticoagulant. The following diagnoses were found in the patient population: human immunodeficiency virus positivity, 20%; systemic lupus erythematosus, 10%; prolonged preoperative activated partial thromboplastin time (APTT), 10%; procainamide h
Human immunodeficiency virus exposure among medical students [letter; comment]: Arch Surg. 1993 Jun;128(6):710. Unique Identifier : AIDSLINE MED/93277368; Jones DB
Antiviral effects of different CD4-immunoglobulin constructs against HIV-1 and SIV: immunological characterization, pharmacokinetic data and in vivo experiments.: Arch Virol. 1993;130(1-2):157-70. Unique Identifier : AIDSLINE MED/93277374; Langner KD; Niedrig M; Fultz P; Anderson D; Reiner G; Repke H; Gelderblom H; Seed B; Hilfenhaus J; Zettlmeissl G; Forschungslabor der Behringwerke AG, Marburg, Federal Republic of; Germany.; The CD4 cell surface antigen belongs to the immunoglobulin superfamily and is the primary receptor for the human immunodeficiency virus 1 (HIV-1). The high affinity interaction between HIV-1 and CD4 is mediated by the viral envelope glycoprotein gp120. Recombinant soluble CD4 (rsCD4) has been shown in vitro to be an e
Vitamin B12 deficiency neuropsychiatric damage in acquired immunodeficiency syndrome [letter; comment]: Arch Neurol. 1993 Jun;50(6):569. Unique Identifier : AIDSLINE MED/93277389; Herbert V
Inhibition of NF-kappa B activation by vitamin E derivatives.: Biochem Biophys Res Commun. 1993 May 28;193(1):277-83. Unique Identifier : AIDSLINE MED/93277563; Suzuki YJ; Packer L; Department of Molecular & Cell Biology, University of California,; Berkeley 94720.; Nuclear factor kappa B (NF-kappa B) is believed to play an important role in the activation of a human immunodeficiency virus (HIV) which causes acquired immunodeficiency syndrome (AIDS). Recent findings suggesting an involvement of reactive oxygen species in signal transduction pathways leading to NF-kappa B activati
Recombination between human immunodeficiency viruses (HIV) type 1 and 2 results in generation of defective hybrid viruses.: Biochem Biophys Res Commun. 1993 May 28;193(1):311-7. Unique Identifier : AIDSLINE MED/93277568; Ranganathan PN; Srinivasan A; Dept. of Biochemistry, Thomas Jefferson University, Philadelphia,; PA 19107.; Dual infection by HIV-1 and HIV-2 is already documented. To test if this could lead to recombination and generation of altered viruses, recombination between HIV-1 and HIV-2 DNAs was studied. Release of recombinant viruses was detected following cotransfection of human rhabdomyosarcoma cells with truncated versions of
Global programme on AIDS. HIV antibody detection in oral fluids.: Wkly Epidemiol Rec. 1993 May 7;68(19):133-4. Unique Identifier : AIDSLINE MED/93277786
HTLV-1-associated cutaneous disease: a clinicopathological and molecular study of patients from the U.K.: Br J Dermatol. 1993 May;128(5):483-92. Unique Identifier : AIDSLINE MED/93277789; Whittaker SJ; Ng YL; Rustin M; Levene G; McGibbon DH; Smith NP; St John's Dermatology Centre, St Thomas' Hospital, London, U.K.; The clinicopathological features of eight patients with cutaneous disease associated with HTLV-1 infection are reviewed. All were U.K. residents of West Indian extraction, and two are currently alive. Disease remained confined to the skin in two patients. Five patients with a cutaneous prodromal phase developed leukae
Structures and functions of the K rev-1 transformation suppressor gene and its relatives.: Biochim Biophys Acta. 1993 May 25;1155(1):97-109. Unique Identifier : AIDSLINE MED/93277910; Noda M; Department of Viral Oncology, Cancer Institute, Japanese; Foundation for Cancer Research, Tokyo, Japan.
Glycosphingolipid compositions of human T-lymphotropic virus type I (HTLV-I) and human immunodeficiency virus (HIV)-infected cell lines.: Biochim Biophys Acta. 1993 Jun 12;1168(2):123-9. Unique Identifier : AIDSLINE MED/93277927; Matsuda K; Taki T; Hamanaka S; Kasama T; Rokukawa C; Handa S; Yamamoto N; Department of Microbiology, Faculty of Medicine, Tokyo Medical; and Dental University, Japan.; Glycolipid compositions of cells infected by human retroviruses (human immunodeficiency virus, HIV and/or human T-cell lymphotropic virus type I, HTLV-I) have been studied. Eight cell lines, comprising two HTLV-I-infected T-cell lines (MT-2 and MT-4), two HTLV-I-negative T-cell lines (Jurkat and MF), a macrophage cell
Inhibition of HIV proliferation in MT-4 cells by antisense oligonucleotide conjugated to lipophilic groups.: Biochimie. 1993;75(1-2):49-54. Unique Identifier : AIDSLINE MED/93277975; Svinarchuk FP; Konevetz DA; Pliasunova OA; Pokrovsky AG; Vlassov VV; Institute of Bioorganic Chemistry, Institute of Molecular; Biology, Koltsovo, Novosibirsk Region, Russia.; Anti-HIV activity of antisense oligonucleotide derivatives conjugated to lipophilic groups has been investigated. Aliphatic linear structures and cholesterol were coupled to the 5 -terminal phosphate of oligonucleotides via glycine or propylene diamine spacers. The oligonucleotides were targeted to a conserved sequenc
[Risk of infection transmission by blood components]: Infusionsther Transfusionsmed. 1993 Apr;20(1-2):54-9. Unique Identifier : AIDSLINE MED/93278089; Kubanek B; Cardoso M; Gluck D; Koerner K; DRK-Blutspendezentrale Ulm, BRD.; OBJECTIVE: Assessment of the present risk of blood-borne infection associated with homologous blood transfusion in Central Europe with particular emphasis on HIV and HCV infections. DATA SOURCES: The relevant literature in the English and German language and the authors data. STUDY SELECTION: No special study has bee
[Seroprevalence of human immunodeficiency virus infection (HIV) in Mali on 3,496 sera]: Bull Soc Pathol Exot. 1993;86(1):16-20. Unique Identifier : AIDSLINE MED/93278116; Maiga MY; Diarra B; Guindo A; Maiga YI; Fofano O; Bougoudogo F; Service d'Hepato-Gastro-Enterologie, Hopital Gabriel-Toure,; Bamako, Mali.; Our main objective has been geared toward the appreciation of the importance of the infection by human immunodeficiency virus in Mali . Our study was based on 3,496 sera deducted from March 1987 to January 1989. All positive sera at ELISA have been confirmed by Western Blot. The total
Pentamidine aerosol for prophylaxis of Pneumocystis carinii pneumonia after BMT.: Bone Marrow Transplant. 1993 May;11(5):403-6. Unique Identifier : AIDSLINE MED/93278349; Link H; Vohringer HF; Wingen F; Bragas B; Schwardt A; Ehninger G; Department of Haematology and Oncology, Medizinische Hochschule,; Hannover, Germany.; Following BMT there is a 5-15% risk of interstitial pneumonia caused by Pneumocystis carinii (PcP). Cotrimoxazole is therefore administered prophylactically, but may cause myelodepression, allergic reactions and nephrotoxicity. As PcP prophylaxis with pentamidine aerosol is effective in patients with AIDS, we conducte
[Cohort study of HIV infection among drug users in Ruili City and Longchuan County, Yunnan Province, China]: Chung Hua Liu Hsing Ping Hsueh Tsa Chih. 1993 Feb;14(1):3-5. Unique Identifier : AIDSLINE MED/93278734; Zheng X; Institute of Epidemiology and Microbiology, Chinese Academy of; Preventive Medicine, Beijing.; In March 1992, KAP investigation and HIV blood test were carried out for 860 drug users and 82 spouses in Ruili, Luxi, Longchuan of Yunnan Province, China . The results show that there were 285 IDUs (33.1%) among 860 drug users. Among 282 blood samples of IDUs, the HIV infection rate
Pharmacokinetic optimisation in the treatment of Pneumocystis carinii pneumonia.: Clin Pharmacokinet. 1993 May;24(5):388-412. Unique Identifier : AIDSLINE MED/93278953; Vohringer HF; Arasteh K; Auguste-Viktoria-Krankenhaus, Freien Universitat Berlin, Federal; Republic of Germany.; Several drugs and drug combinations are currently used in the treatment of patients with Pneumocystis carinii pneumonia (PCP)--pentamidine and cotrimoxazole (trimethoprim plus sulphamethoxazole), which are indicated for this usage, dapsone/trimethoprim and clindamycin/primaquine, which are not licensed for PCP, and tr
Etiopathological investigation of Mooren's ulcer.: Chin Med J (Engl). 1993 Jan;106(1):57-60. Unique Identifier : AIDSLINE MED/93279081; Zhao JC; Jin XY; Department of Immunology and Microbiology, Beijing Institute of; Ophthalmology.; Using the indirect immunofluorescence test (IFT), the authors examined the sera of 16 patients with Mooren s ulcer for the presence of antibodies against normal rabbit and human corneal epithelial cells, and determined the percentages of T-lymphocyte subsets in the peripheral blood of the patients and controls. The re
A novel human tyrosine kinase gene inducible in T cells by interleukin 2.: FEBS Lett. 1993 Jun 7;324(1):1-5. Unique Identifier : AIDSLINE GENBANK/D13720; Tanaka N; Asao H; Ohtani K; Nakamura M; Sugamura K; Department of Microbiology, Tohoku University School of Medicine,; Sendai, Japan.; We have cloned a novel human protein tyrosine kinase gene specific to T cells by the polymerase chain reaction method. This gene encodes a 620 amino-acid polypeptide including a catalytic domain for tyrosine kinase, an SH2 domain and an SH3 domain, seemingly belonging to the src family. However, characteristics of a l
The detection of HIV-2 infection in southern India.: Indian J Med Res. 1993 Mar;97:49-52. Unique Identifier : AIDSLINE MED/93279753; Babu PG; Saraswathi NK; Devapriya F; John TJ; Department of Virology & Immunology, Christian Medical College; Hospital, Vellore.; To determine the prevalence of HIV-2 infection in southern India , we tested two sets of sera, selected from among the samples which had been collected between January 1988 and October 1990 from high risk subjects and tested for HIV-1 antibody. They were screened for HIV-2 antibody b
CD4-binding compounds: an assay to detect new classes of immunopharmacological agents.: Int J Immunopharmacol. 1993 Apr;15(3):361-9. Unique Identifier : AIDSLINE MED/93279838; Chandler G; Elcock C; Depledge P; Wrigley S; Mous J; Malkovsky M; Moore M; Gammon G; Xenova Ltd, Slough, U.K.; The interaction of antibodies with protein antigens is accepted as a paradigm of protein-protein interactions. In searching for a new generation of immunomodulatory compounds based on the interaction of the T-cell surface glycoprotein CD4 with MHC class II antigens, a model assay has been developed in which MHC molecu
Geographical variations in the prevalence of HIV infection among drug users receiving ambulatory treatment in Spain.: Int J Epidemiol. 1993 Apr;22(2):306-14. Unique Identifier : AIDSLINE MED/93279886; Lardelli P; de la Fuente L; Alonso JM; Lopez R; Bravo MJ; Delgado-Rodriguez M; Department of Preventive Medicine, School of Medicine, University; of Granada, Spain.; To identify the factors responsible for the regional differences in HIV-positive serostatus among drug users in Spain receiving outpatient treatment, the 17 autonomous regions into which Spain is divided were classified as high (mean 52%) or low prevalence groups (mean 34%) dependin
Differences in mortality rates and causes of death between HIV positive and HIV negative intravenous drug users.: Int J Epidemiol. 1993 Apr;22(2):315-20. Unique Identifier : AIDSLINE MED/93279887; Eskild A; Magnus P; Samuelsen SO; Sohlberg C; Kittelsen P; Department of Epidemiology, National Institute of Public Health,; Oslo, Norway.; In order to study differences in mortality and causes of death between HIV positive and HIV negative intravenous drug users (IVDU), 1009 (180 HIV positive and 829 HIV negative) IVDU in Oslo, Norway , were followed from their first HIV test for a mean period of 36 months (range 1-67
Evaluating modifications in epidemic surveillance systems: a method and an application to AIDS surveillance in Switzerland.: Int J Epidemiol. 1993 Apr;22(2):321-6. Unique Identifier : AIDSLINE MED/93279888; Engel RR; School of Public Health, Department of Biomedical and; Environmental Health Sciences, University of California, Berkeley; 94720.; A method is presented for evaluating the impact of a modification in a surveillance system for an epidemic disease among reporting sources susceptible to the modification. The approach requires a control series with reports from sources that are not affected by the modification. The measure of effect is the reporting
Cell tropism and HIV infection.: J Clin Apheresis. 1993;8(1):13-8. Unique Identifier : AIDSLINE MED/93280087; Davis BR; Geraldine Brush Cancer Research Institute, San Francisco, CA; 94115.
HIV and host immune responses in AIDS pathogenesis.: J Clin Apheresis. 1993;8(1):19-28. Unique Identifier : AIDSLINE MED/93280088; Levy JA; Department of Medicine, University of California School of; Medicine, San Francisco 94143-0128.
The uniqueness of HIV infection.: J Clin Apheresis. 1993;8(1):2-6. Unique Identifier : AIDSLINE MED/93280089; Mielke CH Jr; Health Research and Education Center, Washington State; University, Spokane 99204.
Early infection and serological markers associated with HIV infection.: J Clin Apheresis. 1993;8(1):7-12. Unique Identifier : AIDSLINE MED/93280090; Allain JP; National Blood Transfusion Service, University of Cambridge,; England.
Lipopolysaccharide induces phosphorylation of MAD3 and activation of c-Rel and related NF-kappa B proteins in human monocytic THP-1 cells.: J Biol Chem. 1993 Jun 5;268(16):11803-10. Unique Identifier : AIDSLINE MED/93280143; Cordle SR; Donald R; Read MA; Hawiger J; Department of Microbiology and Immunology, Vanderbilt University; School of Medicine, Nashville, Tennessee 37232.; Many effects of lipopolysaccharide (LPS) on gene expression, including that of human immunodeficiency virus (HIV), in monocytic cells are mediated by activation of kappa B DNA-binding proteins. However, the specific members of the NF-kappa B/Rel transcription factor family involved in the LPS response, and the mechani
Regulation of autoproteolysis of the HIV-1 and HIV-2 proteases with engineered amino acid substitutions.: J Biol Chem. 1993 Jun 5;268(16):11939-45. Unique Identifier : AIDSLINE MED/93280162; Rose JR; Salto R; Craik CS; Department of Pharmacology, University of California, San; Francisco 94143-0446.; Autoproteolysis of the retroviral aspartyl proteases is a major obstacle to purification and analysis of these enzymes. A mutagenic approach to rendering autolytic cleavage sites less labile was applied to the primary cleavage site between Leu5 and Trp6 in human immunodeficiency virus-1 (HIV-1) protease. From predicti
Cytoimmunological abnormalities in cerebrospinal fluid in early stages of HIV-1 infection often precede changes in blood.: J Neuroimmunol. 1993 May;44(2):199-204. Unique Identifier : AIDSLINE MED/93280312; Elovaara I; Muller KM; Department of Microbiology, Aurora Hospital, Helsinki, Finland.; We determined the proportions of CD2+, CD4+ and CD8+ lymphocytes in the cerebrospinal fluid (CSF) and paired blood samples of 19 neurologically examined subjects with CDC II/III stage HIV-1 infection and 21 controls. Using a three-layer indirect immunoperoxidase technique, we found that 16 HIV-1-infected subjects had
Determining the HIV status of patients of three HIV-positive Navy dentists.: J Am Dent Assoc. 1993 Jun;124(6):74-7. Unique Identifier : AIDSLINE MED/93280372; York AK; Arthur JS; Naval Dental Research Institute Detachment, National Naval Dental; Center, Bethesda, Md. 20889-5602.; The prevalence of human immunodeficiency virus infection has caused the risk of HIV transmission in the health care setting to become a major public concern. Navy medical records were reviewed to investigate the HIV status of 2,887 patients treated by three HIV-positive dentists.
Pediatric AIDS: a longitudinal comparative MRI and CT brain imaging study.: J Child Neurol. 1993 Apr;8(2):175-81. Unique Identifier : AIDSLINE MED/93280404; Chamberlain MC; Department of Neurosciences, University of California, San Diego,; 92103.; Fourteen consecutive children with acquired immune deficiency syndrome (AIDS) (age range, 4 months to 11 years; median 4 years) were studied prospectively comparing nonenhanced cranial magnetic resonance imaging (MRI) and computed tomographic (CT) scans. MRI and CT were performed twice: at time of entry into protocol
Clostridium difficile diarrhea in patients with AIDS versus non-AIDS controls. Methods of treatment and clinical response to treatment.: J Clin Gastroenterol. 1993 Apr;16(3):192-4. Unique Identifier : AIDSLINE MED/93280412; Cozart JC; Kalangi SS; Clench MH; Taylor DR; Borucki MJ; Pollard RB; Soloway RD; Division of Gastroenterology, University of Texas Medical Branch,; Galveston 77555.; We reviewed the hospital charts of 17 patients with AIDS and Clostridium difficile diarrhea to determine antibiotic use before C. difficile infection, methods of treatment for C. difficile diarrhea, and response of diarrhea to treatment. Left shift and total white blood cell count before and after treatment for C. dif
Diagnostic workup strategies for patients with HIV-related chronic diarrhea. What is the end result?: J Clin Gastroenterol. 1993 Apr;16(3):245-50. Unique Identifier : AIDSLINE MED/93280426; Rabeneck L; Department of Medicine, Baylor College of Medicine, VA Medical; Center, Houston, Texas 77030.; The intensity of diagnostic workup of patients with human immunodeficiency virus (HIV)-related chronic diarrhea is controversial. In the ideal setting in which an enteric pathogen is detected with minimal evaluation (stool tests) and in which specific treatment clears the diarrhea, eradicates the pathogen, and improve
Endoscopic characterization of idiopathic esophageal ulceration associated with human immunodeficiency virus infection.: J Clin Gastroenterol. 1993 Apr;16(3):251-6. Unique Identifier : AIDSLINE MED/93280427; Wilcox CM; Schwartz DA; Department of Medicine, Emory University School of Medicine,; Atlanta, Georgia.; Idiopathic esophageal ulcerations (IEUs) associated with human immunodeficiency virus (HIV) infection are now recognized as an important cause of esophageal disease in this population. Limited radiographic and endoscopic reports have almost uniformly described these lesions as solitary and giant. Over a 28-month perio
Detection of inhibition of HIV-1 protease activity by an enzyme-linked immunosorbent assay (ELISA).: J Immunol Methods. 1993 May 26;161(2):151-5. Unique Identifier : AIDSLINE MED/93280477; Mansfeld HW; Schulz S; Grutz G; von Baehr R; Ansorge S; Department of Internal Medicine, Medical Academy of Magdeburg,; Germany.; An ELISA is described for the detection of HIV-1 protease activity using an immobilized gag-related polyprotein as substrate. Proteolytic activity was demonstrated with either bacterial lysates expressing HIV-1 protease or purified protease. No cleavage was observed with a protein preparation from control bacteria not
Diagnosis of Pneumocystis carinii pneumonia in a population of HIV-positive drug users, with particular reference to sputum induction and fluorescent antibody techniques.: J Infect. 1993 May;26(3):257-64. Unique Identifier : AIDSLINE MED/93280495; Willocks L; Burns S; Cossar R; Brettle R; Regional Infectious Diseases Unit, City Hospital, Edinburgh, U.K.; Between June 1990 and May 1991, 200 sputum inductions were examined by a fluorescent antibody test (FAT) for Pneumocystis carinii (PC). A total of 164 specimens were negative, 36 were positive and a further 20 inductions were unsuccessful. All patients with a positive result, seven of whom had normal chest X-rays and
Tuberculosis/HIV co-infection in India's north-eastern states [letter]: J Infect. 1993 May;26(3):344-5. Unique Identifier : AIDSLINE MED/93280515; Singh NB; Singh EK; Singh HL; Singh YI
Early confirmation of HIV p24 antigenaemia in infants born of HIV-positive mothers [letter]: J Infect. 1993 May;26(3):349-51. Unique Identifier : AIDSLINE MED/93280520; Corbitt G
Two central nervous system infectious diseases in a patient with AIDS.: J Fam Pract. 1993 Jun;36(6):660-4. Unique Identifier : AIDSLINE MED/93280558; Murray-Pulsifer K; Central Maine Medical Center, Lewiston 04240.; As medical interventions prolong the lives of patients with acquired immunodeficiency syndrome (AIDS), we have begun to observe multiple infections occurring simultaneously in a single patient. This report describes two central nervous system (CNS) infections, cryptococcal meningitis and cerebral toxoplasmosis, coexis
AIDS epidemic among Florida women.: J Fla Med Assoc. 1993 Apr;80(4):246-9. Unique Identifier : AIDSLINE MED/93280563; Conti L; Lieb S; Spradling T; Witte JJ; Department of Health and Rehabilitative Services, Tallahassee.; Impact of the human immunodeficiency virus among women in Florida is increasingly recognized in the second decade of the AIDS epidemic. Illicit drug use, sexual activity with multiple partners, lack of access to health care, and socioeconomic disadvantages are greatly contributing to the increase of female AIDS cases.
Emergency room care for hemophiliac patients. Understanding and overcoming difficulties.: J Fla Med Assoc. 1993 Apr;80(4):250-4. Unique Identifier : AIDSLINE MED/93280564; Hemophiliac patients represent a unique challenge to emergency room physicians. They are particularly well educated and experienced in their disease and its treatment, whereas emergency room doctors may have little experience with management. This paradoxical situation often leads to frustration for both; it need not
Neuronal number and volume alterations in the neocortex of HIV infected individuals.: J Neurol Neurosurg Psychiatry. 1993 May;56(5):481-6. Unique Identifier : AIDSLINE MED/93280591; Everall IP; Luthert PJ; Lantos PL; Department of Neuropathology, Institute of Psychiatry, London,; UK.; Substantial neuronal loss in the superior frontal gyrus in patients who have died of AIDS have been reported previously. This investigation examined the distribution of neuronal loss in three other neocortical areas and, alteration in neuronal volume in four neocortical areas. This was carried out using two stereologi
Neuronal loss in the hippocampus in Huntington's disease: a comparison with HIV infection.: J Neurol Neurosurg Psychiatry. 1993 May;56(5):487-91. Unique Identifier : AIDSLINE MED/93280592; Spargo E; Everall IP; Lantos PL; Department of Neuropathology, Institute of Psychiatry, London,; UK.; The hippocampus is usually affected in primary dementias and the pathological changes may be severe. Knowledge of hippocampal pathology in HIV infection and Huntington s disease (HD), however, is extremely limited. A stereological technique (the optical disector) has been used to assess neuronal populations in four ar
Substance abuse and AIDS: a faculty development program for primary care providers.: J Gen Intern Med. 1993 May;8(5):266-8. Unique Identifier : AIDSLINE MED/93280657; O'Connor PG; Bigby J; Gallagher D; Department of Internal Medicine, Yale University School of; Medicine, New Haven, CT 06510.; The authors implemented a three-day faculty development program on substance abuse and AIDS for primary care faculty. Objectives included: 1) increased knowledge concerning clinical issues; 2) skill development focusing on provider-patient interactions; and 3) the development of educational approaches for teaching abo
Reactive serological tests for syphilis in tropical spastic paraparesis: a dilemma.: J Trop Med Hyg. 1993 Jun;96(3):172-4. Unique Identifier : AIDSLINE MED/93280761; Barton EN; Morgan OS; Smikle MF; Blattner WA; Department of Medicine, University of the West Indies, Mona,; Jamaica.; The prevalence of reactive serological tests for syphilis (STS) was investigated in 183 Jamaican patients with tropical spastic paraparesis (TSP) and 200 age and sex matched controls. A significantly higher prevalence of reactive STS was found in TSP patients (34.9%) compared with controls (14.0%, P
[Ancient serological traces of infections by the human immunodeficiency virus HIV-1 and HIV-2 in sub-saharan Africa. A different geography]: Med Trop (Mars). 1993 Jan-Mar;53(1):33-43. Unique Identifier : AIDSLINE MED/93280990; Remy G; Ecole des Hautes Etudes en Sciences Sociales, Marseille.; Despite of some heavy methodological limitations, the analysis of some serological data collected before 1985 allows to establish the selective regional distribution of the two infections. HIV-2 is prevalent in the West African sites which are studied and he has been observed since the sixties. The foci and the sporad
[The pathogenicity of the human immunodeficiency virus HIV-2 as seen by epidemiologists]: Med Trop (Mars). 1993 Jan-Mar;53(1):45-53. Unique Identifier : AIDSLINE MED/93280991; Soro BN; Gershy-Damet GM; Rey JL; Service d'Epidemiologie-Institut National de Sante Publique,; Abidjan-Cote d'Ivoire.; The purpose of this study is an evaluation of HIV-2 pathogenicity through an epidemiological analysis, specially in Africa. It is acknowledged that the incubation, or more specially the lapse of time between the infection and the AIDS disease, is longer with HIV-2 than with HIV-1. More over, a certain number of survey
[Infection by the human immunodeficiency virus in the Republic of Djibouti: literature review and regional data]: Med Trop (Mars). 1993 Jan-Mar;53(1):61-7. Unique Identifier : AIDSLINE MED/93280993; Rodier G; Couzineau B; Salah S; Bouloumie J; Parra JP; Fox E; Constantine N; Watts D; US Naval Medical Research Unit n. 3, (NAMRU-3) Le Caire Egypte.; The first evidence of HIV infection in Djibouti , East Africa, was found in the spring of 1986; the first case of acquired immunodeficiency syndrome (AIDS) was diagnosed in March 1988; and, as of the end of 1991, 104 cases of AIDS had been reported. HIV-1 infection was predominant
HIV never dormant [news]: Minn Med. 1993 May;76(5):42. Unique Identifier : AIDSLINE MED/93281036
Suit filed over AIDS coverage [news]: Minn Med. 1993 May;76(5):42. Unique Identifier : AIDSLINE MED/93281037
Early detection of HIV in neonates [letter; comment]: N Engl J Med. 1993 Jul 1;329(1):60-1; discussion 61-2. Unique Identifier : AIDSLINE MED/93281154; Fauvel M; Henrard D; Delage G; Lapointe N
Early detection of HIV in neonates [letter; comment]: N Engl J Med. 1993 Jul 1;329(1):61; discussion 61-2. Unique Identifier : AIDSLINE MED/93281155; Fiscus SA; Vernazza P; Lim W
Contaminated blood case nears end [news]: Nature. 1993 Jun 10;363(6429):491. Unique Identifier : AIDSLINE MED/93281176; Maddox J
[Indications for brain biopsy in the diagnosis of intracerebral lesions in patients with AIDS]: Ned Tijdschr Geneeskd. 1993 May 15;137(20):999-1002. Unique Identifier : AIDSLINE MED/93281203; Portegies P; Enting RH; Troost D; Bosch DA; Afd. Neurologie, Academische Medisch Centrum, Amsterdam.
[Myasthenia gravis in AIDS and neurosyphilis]: Nervenarzt. 1993 Apr;64(4):273-7. Unique Identifier : AIDSLINE MED/93281226; Wullenweber M; Schneider U; Hagenah R; Neurologische Abteilung, Diakoniekrankenhauses, Rotenburg/Wumme.; The co-occurrence of myasthenia gravis and AIDS in a 38 year old drug addict with HIV-infection is reported. The diagnosis myasthenia gravis is based on clinical features with muscle weakness worsening with exercise and depending on the time of day, and secondly on the result of electrophysiological tests, with a typi
[Tuberculous radiculomyelitis--good response to therapy only in early detection]: Nervenarzt. 1993 Apr;64(4):282-3. Unique Identifier : AIDSLINE MED/93281228; Botzel K; Neurologische Klinik, Ludwig-Maximilians-Universitat, Munchen.; This is a report of a case of radioculomyelitis secondary to tuberculous meningitis. The importance of an early diagnosis is stressed in the light of reports on good outcome after prompt commencement of therapy. Polymerase chain reaction is now available for quick confirmation of the suspected diagnosis.
[Kaposi's sarcoma--classic form. A rare familial case]: Minerva Chir. 1993 Mar 15;48(5):237-41. Unique Identifier : AIDSLINE MED/93281264; Invernizzi R; Ubiali P; Barcella A; Bonzanini C; Divisione di Chirurgia Generale, USSL 26, Regione Lombardia,; Ospedale di Alzano Lombardo Bergamo.; Although Kaposi s sarcoma became very well-known with the outbreak of AIDS, this pathology in the classic Mediterranean form is still unusual and obscure. Nowadays we identify four types of Kaposi s sarcoma: 1) the classic Mediterranean form, 2) the endemic African one, 3) the therapeutical in immunosuppressed patient
Mandatory AIDS testing could create hospital staffing problems [news]: N J Med. 1993 May;90(5):411. Unique Identifier : AIDSLINE MED/93281341
Arthropathy and HIV infection. A muddle of mimicry.: Postgrad Med. 1993 Jun;93(8):143-6, 149-50. Unique Identifier : AIDSLINE MED/93281451; Malin JK; Patel NJ; Section of Rheumatology, Tulane University School of Medicine,; New Orleans.; Several rheumatic diseases are associated with human immunodeficiency virus (HIV) infection. The most common are reactive and psoriatic arthritis. Classic septic arthritis caused by Staphylococcus aureus and other common organisms is very rare: Instead, infectious arthritis caused by unusual organisms is the rule. Som
A proposal for a new approach to a preventive vaccine against human immunodeficiency virus type 1.: Proc Natl Acad Sci U S A. 1993 May 15;90(10):4419-20. Unique Identifier : AIDSLINE MED/93281590; Temin HM; McArdle Laboratory, Madison, WI 53706.; Human immunodeficiency virus type 1 (HIV-1) is a more complex retrovirus, coding for several accessory proteins in addition to the structural proteins (Gag, Pol, and Env) that are found in all retroviruses. More complex retroviruses have not been isolated from birds, and simpler retroviruses have not been isolated fro
Identification of human endogenous retroviruses with complex mRNA expression and particle formation.: Proc Natl Acad Sci U S A. 1993 May 15;90(10):4480-4. Unique Identifier : AIDSLINE GENBANK/X72791; Lower R; Boller K; Hasenmaier B; Korbmacher C; Muller-Lantzsch N; Lower J; Kurth R; Paul Ehrlich Institute, Langen, Federal Republic of Germany.; Retroviruses comprise strains with considerable disease potential in animals and humans. In addition to exogenous strains transmitted horizontally, endogenous proviruses are transmitted through the germ line. Some of these endogenous retroviruses can be pathogenic in mice and possibly in other animal species. They may
Identification of a binding site for the human immunodeficiency virus type 1 nucleocapsid protein.: Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5219-23. Unique Identifier : AIDSLINE MED/93281729; Sakaguchi K; Zambrano N; Baldwin ET; Shapiro BA; Erickson JW; Omichinski JG; Clore GM; Gronenborn AM; Appella E; Laboratory of Cell Biology, National Cancer Institute, Bethesda,; MD 20892.; The nucleocapsid (NC) protein NCp7 of human immunodeficiency virus type 1 (HIV-1) is important for encapsidation of the virus genome, RNA dimerization, and primer tRNA annealing in vitro. Here we present evidence from gel mobility-shift experiments indicating that NCp7 binds specifically to an RNA sequence. Two comple
[Rheumatological manifestations and HIV infection]: Schweiz Rundsch Med Prax. 1993 Apr 6;82(14):403-9. Unique Identifier : AIDSLINE MED/93281824; Michel BA; Rheumaklinik und Institut fur physikalische Medizin,; Universitatsspital Zurich.; The spectrum of clinical manifestations in HIV infection has expanded considerably over the last few years. Several rheumatological syndromes have been associated with HIV infection such as Reiter s syndrome and other reactive arthritides, undifferentiated spondylarthropathy, but also HLA-B27-negative oligoarthritis,
[A case from practice (268). Dilated cardiomyopathy in AIDS]: Schweiz Rundsch Med Prax. 1993 May 18;82(20):597-9. Unique Identifier : AIDSLINE MED/93281839; Borer H; Ruttimann S; Martina B; Medizinische Universitats-Poliklinik, Departement fur Innere; Medizin, Basel.
Nontuberculous mycobacterial infection of the central nervous system in patients with AIDS.: South Med J. 1993 Jun;86(6):638-40. Unique Identifier : AIDSLINE MED/93281897; Jacob CN; Henein SS; Heurich AE; Kamholz S; School of Medicine, State University of New York-Health Science; Center, Brooklyn.; Infections due to nontuberculous mycobacteria (NTM) are especially common in patients with AIDS. Meningitis due to NTM, however, is rare. A search for CSF cultures positive for NTM over the past 11 years at our hospital yielded 16 cases. Of these, 15 were caused by Mycobacterium avium-intracellular (MAI), and one was
Assessment of medical students' knowledge regarding human immunodeficiency virus transmission: comparisons by gender, residence, and training level [see comments]: South Med J. 1993 Jun;86(6):660-6. Unique Identifier : AIDSLINE MED/93281903; Kittleson MJ; Ragon BM; Venglarcik JS; Department of Health Education, Southern Illinois University,; Carbondale 62901-6618.; As the incidence of human immunodeficiency virus (HIV) infection increases, health care practitioners are being called upon to counsel and educate patients regarding the complications associated with HIV infection. In addition, the anxiety levels of health care workers reveal that similar educational efforts must be i
Polycythemia as a complication of human immunodeficiency virus infection.: South Med J. 1993 Jun;86(6):686-8. Unique Identifier : AIDSLINE MED/93281908; Edwards TB; Nelson RP; Ballester OF; Saba HI; Lockey RF; Department of Internal Medicine, University of South Florida; College of Medicine, Tampa.; HIV infection is commonly associated with cytopenias. The occurrence of erythrocytosis is rare, with only one report in the medical literature. We have described the case of an asymptomatic patient found to be seropositive for HIV. The blood counts were initially normal except for mild eosinophilia and thrombocytopeni
[Incidence of HIV-1 antibodies in drug addicts autopsied at the Institute of Forensic Medicine in Copenhagen in 1988-1991]: Ugeskr Laeger. 1993 Apr 26;155(17):1294-6. Unique Identifier : AIDSLINE MED/93282035; Kringsholm B; Theilade P; Kobenhavns Universitet, Retspatologisk Institut.; During the period 1988-1991 HIV-1-antibody tests were performed on a total of 389 autopsied drug addicts. The HIV-1-incidence rose from 6 per cent in 1988 to 14 per cent in 1990 and 14 per cent in 1991. There was no significant difference between the cumulated incidence in males and females. The HIV-1-positive addicts
[Fatal AIDS hypocrisy and hidden lobbying (letter; comment)]: Ugeskr Laeger. 1993 Apr 26;155(17):1310-2. Unique Identifier : AIDSLINE MED/93282042; Cruger C
[AIDS and behavior (letter; comment)]: Ugeskr Laeger. 1993 Apr 26;155(17):1312. Unique Identifier : AIDSLINE MED/93282043; Henriques UV
Early phenotypic and functional alterations in lymphocytes from simian immunodeficiency virus infected macaques.: Vet Immunol Immunopathol. 1993 Apr;36(3):239-55. Unique Identifier : AIDSLINE MED/93282091; Kneitz C; Kerkau T; Muller J; Coulibaly C; Stahl-Hennig C; Hunsmann G; Hunig T; Schimpl A; Institute of Virology and Immunobiology, University of Wurzburg,; Germany.; Phenotypic and functional changes in lymphocytes from rhesus monkeys (Macaca mulatta) were investigated during the first 6 months after infection with SIV mac 32H. Animals preimmunized with keyhole limpet hemocyanin (KLH) were sacrificed 1, 3, 6, 12, and 24 weeks post infection. Subset composition and function of lymp
[The stress interview after acute myocardial infarct]: Vnitr Lek. 1993 Feb;39(2):178-82. Unique Identifier : AIDSLINE MED/93282157; Vavra P; Sluka V; II. interni oddeleni NsP Havirov.; Patients suffering from myocardial infarction (MI) form the high risk group. Residual ischemia, impaired left ventricular function and dysrhythmias are life endangering. Sudden death is more frequent in this group than in the one of patients with CHD. Therefore before discharge from the hospital we applied to the pati
Electrophysiological study (VEP, BAEP) in HIV-1 seropositive patients with and without AIDS.: Acta Neurol Belg. 1993;93(2):78-87. Unique Identifier : AIDSLINE MED/93282243; Pierelli F; Soldati G; Zambardi P; Garrubba C; Spadaro M; Tilia G; Pauri F; Morocutti C; Istituto di Clinica delle Malattie Nervose e Mental, Universita; degli Studi di Roma La Sapienza.; One hundred-twenty nine HIV-1 seropositive patients (39 females, 90 males) were studied by means of pattern visual evoked potential (VEP) and brainstem auditory evoked potential (BAEP) recording. Utilizing the criteria of the Centers for Disease Control the patients were clinically defined and then subdivided into fou
Acquired immunodeficiency syndrome: no time for kudos [letter; comment]: Am J Dis Child. 1993 Jun;147(6):611. Unique Identifier : AIDSLINE MED/93282367; Murphy J
Body fluid exposure in an urban tertiary care medical center.: Am J Ind Med. 1993 May;23(5):703-10. Unique Identifier : AIDSLINE MED/93282392; Longbottom HM; Cox K; Sokas RK; Department of Occupational and Environmental Medicine, George; Washington University, Washington, DC 20037.; The increasing prevalences of the human immunodeficiency (HIV) and hepatitis B viruses have focused attention on the risks that health care workers face when exposed to potentially infective body fluids. This study establishes a profile of 320 parenteral exposure incidents and 47 exposure incidents to mucous membranes
The role of oral candidiasis in survival and hospitalization patterns: analysis of an inner city hospital human immunodeficiency virus/acquired immune deficiency syndrome registry.: Am J Med Sci. 1993 Jun;305(6):345-53. Unique Identifier : AIDSLINE MED/93282445; Lin RY; Goodhart P; Department of Medicine, St. Vincent's Hospital & Medical Center,; New York, NY 10011.; To assess the effect of oral candidiasis (OC) associated with human immunodeficiency virus (HIV) at initial hospital admission on both survival and hospital use, a retrospective analysis was performed in 1,172 hospitalized patients identified by an HIV surveillance program at an inner city public hospital in East Harl
Progressive ocular toxoplasmosis in patients with acquired immunodeficiency syndrome.: Am J Ophthalmol. 1993 Jun 15;115(6):742-7. Unique Identifier : AIDSLINE MED/93282461; Moorthy RS; Smith RE; Rao NA; Doheny Eye Institute, Los Angeles, CA 90033.; We studied two patients, a 43-year-old Hispanic man with a one-year history of acquired immunodeficiency syndrome (AIDS) and a 34-year-old Hispanic man with newly diagnosed AIDS. Both had necrotizing retinitis that progressed to panophthalmitis and orbital cellulitis. Toxoplasmosis was not diagnosed in the first patie
Postmortem localization of HIV-1 RNA by in situ hybridization in lymphoid tissues of intravenous drug addicts who died unexpectedly.: Am J Pathol. 1993 Jun;142(6):1701-13. Unique Identifier : AIDSLINE MED/93282500; Burke AP; Benson W; Ribas JL; Anderson D; Chu WS; Smialek J; Virmani R; Department of Cardiovascular Pathology, Armed Forces Institute of; Pathology, Washington, D.C. 20306-6000.; The histopathological alterations in lymphoid tissues and the presence of human immunodeficiency virus (HIV-1) RNA were studied in 25 consecutive autopsies of seropositive, apparently asymptomatic, intravenous drug overdose victims without palpable lymphadenopathy. The majority of lymphoid tissues in a given person sh
Cytotoxic effector cell granules recognized by the monoclonal antibody TIA-1 are present in CD8+ lymphocytes in lymph nodes of human immunodeficiency virus-1-infected patients.: Am J Pathol. 1993 Jun;142(6):1750-8. Unique Identifier : AIDSLINE MED/93282505; Tenner-Racz K; Racz P; Thome C; Meyer CG; Anderson PJ; Schlossman SF; Letvin NL; Department of Hematology, Allgemeines Krankenhaus St. Georg.; Hamburg, Germany.; A novel monoclonal antibody (mAB) TIA-1, which recognizes a 15-kd granule-associated protein of cytotoxic T lymphocytes and natural killer cells, has been applied to sections of lymph nodes with human immunodeficiency virus (HIV)-induced lymphadenopathy (follicular hyperplasia and lymphocyte depletion). The protein re
Simian immunodeficiency virus infection of the gastrointestinal tract of rhesus macaques. Functional, pathological, and morphological changes.: Am J Pathol. 1993 Jun;142(6):1759-71. Unique Identifier : AIDSLINE MED/93282506; Heise C; Vogel P; Miller CJ; Halsted CH; Dandekar S; Department of Internal Medicine, University of California, Davis; 95616.; Gastrointestinal dysfunction and wasting are frequent complications of human immunodeficiency virus (HIV) infection. Nutrient malabsorption, decreased digestive enzymes and HIV transcripts have been documented in jejunal mucosa of HIV-infected patients; however, the pathogenesis of this enteropathy is not understood.
Elimination of viral infection risk from blood samples for allergy testing.: Allergy. 1993 Apr;48(3):207-8. Unique Identifier : AIDSLINE MED/93282558; Poulsen LK; Sorensen TB; Laboratory of Medical Allergology, National University Hospital,; Copenhagen, Denmark.
Seroprevalence of human immunodeficiency virus in admitted trauma patients at a southeastern metropolitan/rural trauma center.: Am Surg. 1993 Jun;59(6):384-7. Unique Identifier : AIDSLINE MED/93282642; Rudolph R; Bowen DG; Boyd CR; Jurgensen P; Department of Surgery, Memorial Medical Center, Savannah, Georgia; 31403.; Human Immunodeficiency Virus (HIV) seropositivity was prospectively evaluated for trauma patients admitted to Memorial Medical Center between September 1989 and August 1990. Epidemiologic data, HIV risk factors, and opportunity for body fluid exposure were compiled for 520 admitted trauma patients 15 years of age or o
Structural changes in the N-linked sugar chains of serum immunoglobulin G of HTLV-I transgenic mice.: Biochem Biophys Res Commun. 1993 May 14;192(3):1004-10. Unique Identifier : AIDSLINE MED/93282796; Endo T; Iwakura Y; Kobata A; Department of Biochemistry, University of Tokyo, Japan.; IgGs were purified from the sera of HTLV-I transgenic and nontransgenic mice. Comparative studies of the N-linked sugar chains released by hydrazinolysis revealed that their structures of transgenic IgG are quite different from those of nontransgenic IgG. Although both IgGs contained biantennary complex-type oligosacc
Erythropoietin receptor binds to Friend virus gp55 through other membrane components.: Biochem Biophys Res Commun. 1993 May 14;192(3):1131-8. Unique Identifier : AIDSLINE MED/93282814; Kishi A; Chiba T; Sugiyama M; Machide M; Nagata Y; Amanuma H; Taira H; Katsumata T; Todokoro K; Tsukuba Life Science Center, Institute of Physical and Chemical; Research (RIKEN), Ibaraki, Japan.; Direct interactions of Friend spleen focus-forming virus glycoprotein gp55 with either erythropoietin receptor (EpoR) or interleukin (IL)2 receptor beta chain (IL2R) (but not with IL3 receptor) have been reported to induce factor-independent prolonged proliferation of erythroid or lymphoid cells. In order to clarify t
Sicca syndrome associated with human immunodeficiency virus infection: an immunohistochemical study.: Arthritis Rheum. 1993 Jun;36(6):875-6. Unique Identifier : AIDSLINE MED/93282883; Coll J; Tomas S; Corominas JM; Gutierrez J; Hospital del Mar, Universidad Autonoma de Barcelona, Spain.
New device protects skin from AIDS virus and other blood pathogens [news]: Ostomy Wound Manage. 1993 Apr;39(3):94, 96. Unique Identifier : AIDSLINE MED/93282952
Prognostic value of the CD4/CD8 lymphocyte ratio in moderately burned patients.: Burns. 1993 Jun;19(3):198-201. Unique Identifier : AIDSLINE MED/93282974; Rioja LF; Alonso P; de Haro J; de la Cruz J; Servicio de Cirugia Plastica y Quemados, Hospital Reina Sofia,; Cordoba, Spain.; We investigated CD3+, CD4+ and CD8+ T-cell subpopulations, as well as the CD4/CD8 ratio in 84 moderately burned patients with injuries affecting 11-36 per cent of their total body surface area (TBSA). These lymphocyte subpopulations were quantified by indirect immunofluorescence measurement 7 and 60 days postburn. The
Surface plasmon resonance for detection and measurement of antibody-antigen affinity and kinetics.: Curr Opin Immunol. 1993 Apr;5(2):282-6. Unique Identifier : AIDSLINE MED/93283049; Malmqvist M; Pharmacia Biosensor AB, Uppsala, Sweden.; Kinetic and affinity information on biospecific interaction can be generated by analysis of adsorption of analyte to immobilized ligand on a sensor based analytical system. The analysis can be performed free of label and directly using culture supernatants. It was found to be particularly valuable for analysis of anti
Drug interactions with zidovudine [editorial]: AIDS. 1993 Apr;7(4):445-60. Unique Identifier : AIDSLINE MED/93283052; Burger DM; Meenhorst PL; Koks CH; Beijnen JH
Antigenic variation of the dominant gp41 epitope in Africa.: AIDS. 1993 Apr;7(4):461-6. Unique Identifier : AIDSLINE MED/93283053; Lange JM; Teeuwsen VJ; Boucher CA; Vahlne A; Barin F; Tjong-A-Hung S; Dekker J; Parkhede U; de Wolf F; Goudsmit J; Department of Virology, University of Amsterdam, The Netherlands.; OBJECTIVE: To determine the value of (combinations of) synthetic peptides representing immunodominant sites on HIV-1/HIV-2 transmembrane proteins for the detection and discrimination between HIV-1 and HIV-2 infection in various populations. DESIGN AND METHODS: Two 24-mer synthetic peptides derived from immunodominant
Greater diversity of the HIV-1 V3 neutralization domain in Tanzania compared with The Netherlands: serological and genetic analysis.: AIDS. 1993 Apr;7(4):467-74. Unique Identifier : AIDSLINE MED/93283054; Zwart G; Wolfs TF; Bookelman R; Hartman S; Bakker M; Boucher CA; Kuiken C; Goudsmit J; Department of Virology, Academic Medical Centre, Amsterdam, The; Netherlands.; OBJECTIVE: To compare variation in the HIV-1 V3 neutralization domain in Tanzania and The Netherlands . METHODS: For serologic analysis, the specificity of anti-V3 antibodies (immunoglobulin G) for a panel of V3 peptides was determined in
Cost-effective diagnosis of HIV-1 and HIV-2 by recombinant-expressed env peptide (566/996) dot-blot analysis.: AIDS. 1993 Apr;7(4):475-81. Unique Identifier : AIDSLINE MED/93283055; Gueye-Ndiaye A; Clark RJ; Samuel KP; Ndour-Sarr AN; Ouangre A; Sangare L; Mboup S; Marlink RG; Papas TS; Child RH; et al; Laboratory of Bacteriology and Virology, University Cheikh Anta; Diop, Dakar, Senegal.; OBJECTIVE: To characterize the recombinant env peptides, 566 (HIV-1) and 996 (HIV-2), for their ability to serodiagnose HIV-1 and HIV-2 infection. To develop a cost-effective dot-blot format for these peptides, and to evaluate its performance in a developing country laboratory. DESIGN: The recombinant env peptides wer
Accurate detection of maternal antibodies to HIV in newborn whole blood dried on filter paper.: AIDS. 1993 Apr;7(4):483-8. Unique Identifier : AIDSLINE MED/93283056; Pappaioanou M; Kashamuka M; Behets F; Mbala S; Biyela K; Davachi F; George JR; Green TA; Dondero TJ; Heyward WL; et al; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, GA 30333.; OBJECTIVE: The testing of neonatal blood specimens dried on filter paper for maternal HIV antibodies, using an enzyme immunoassay (EIA) with confirmation of repeatedly reactive specimens by immunoblot (IB), was first described in 1987. It has been used to conduct large, unlinked, anonymous HIV seroprevalence surveys f
Cell surface proteins binding to recombinant soluble HIV-1 and HIV-2 transmembrane proteins.: AIDS. 1993 Apr;7(4):489-95. Unique Identifier : AIDSLINE MED/93283057; Ebenbichler CF; Roder C; Vornhagen R; Ratner L; Dierich MP; Institut fur Hygiene, Leopold Franzens Universitat, Innsbruck,; Austria.; OBJECTIVE: To further characterize cell surface proteins binding to recombinant soluble (rs) forms of the transmembrane glycoproteins gp41 of HIV-1 (rsgp41) and gp36 of HIV-2 (rsgp36). METHODS: Various human and murine cell lines of different lineages were surface-labelled with 125I. rsgp41 and rsgp36 were bound to Cn
Progression to AIDS in French haemophiliacs: association with HLA-B35.: AIDS. 1993 Apr;7(4):497-500. Unique Identifier : AIDSLINE MED/93283058; Sahmoud T; Laurian Y; Gazengel C; Sultan Y; Gautreau C; Costagliola D; B3E, INSERM U263, SC4, Universite Pierre et Marie Curie, Paris,; France.; OBJECTIVE: To evaluate whether HLA-B35 influences progression to AIDS in HIV-seropositive subjects with haemophilia. DESIGN: Retrospective (before 1985) and prospective (after 1985) follow-up of a group of French haemophiliacs. METHODS: We studied 144 seropositive patients with moderate or severe haemophilia A or B or
Thrice-weekly cotrimoxazole is better than weekly dapsone-pyrimethamine for the primary prevention of Pneumocystis carinii pneumonia in HIV-infected patients.: AIDS. 1993 Apr;7(4):501-6. Unique Identifier : AIDSLINE MED/93283059; Podzamczer D; Santin M; Jimenez J; Casanova A; Bolao F; Gudiol GR; Infectious Disease Service, Ciudad Sanitaria de Bellvitge,; Barcelona, Spain.; OBJECTIVE: To compare the efficacy and safety of two intermittent regimens for the simultaneous primary prevention of Pneumocystis carinii pneumonia (PCP) and toxoplasmosis in HIV-infected patients. DESIGN: Prospective randomized open trial. SETTING: HIV outpatient clinic of an Infectious Disease Service and a 1000-be
Neuropsychological performance in symptomatic and asymptomatic HIV infection [see comments]: AIDS. 1993 Apr;7(4):519-24. Unique Identifier : AIDSLINE MED/93283062; Bornstein RA; Nasrallah HA; Para MF; Whitacre CC; Rosenberger P; Fass RJ; Department of Psychiatry, Ohio State University, Columbus.; OBJECTIVE: To examine cognitive function in patients at various stages of HIV infection, and to determine the nature and severity associated with stage of illness. DESIGN: Subjects were administered an extensive battery of neuropsychological tests. SUBJECTS: Two hundred and thirty-three HIV-1-infected homosexual/bisex
Economic impact of the AIDS epidemic in the European Community: towards multinational scenarios on hospital care and costs.: AIDS. 1993 Apr;7(4):541-53. Unique Identifier : AIDSLINE MED/93283065; Postma MJ; Leidl R; Downs AM; Rovira J; Tolley K; Gyldmark M; Jager JC; National Institute of Public Health and Environmental Protection,; Bilthoven, The Netherlands.; OBJECTIVE: To underpin multinational public-health HIV/AIDS strategy planning in the European Community (EC) by integrating national studies on HIV/AIDS in scenario analysis. METHOD: Three types of data are used: routine surveillance data, information on disease progression and observational studies on the economic im
Patient use and assessment of conventional and alternative therapies for HIV infection and AIDS.: AIDS. 1993 Apr;7(4):561-5. Unique Identifier : AIDSLINE MED/93283067; Anderson W; O'Connor BB; MacGregor RR; Schwartz JS; History of Science Department, Harvard University, Cambridge,; Massachusetts 02138.; OBJECTIVE: To investigate the extent of recourse to alternative therapies among 184 HIV-positive patients who continued to attend conventional medical clinics. The study describes the specific alternative therapeutic modalities that were more commonly sought by our respondents, and provides data on the subjective asse
Sentinel surveillance for HIV-1 infection: how representative are blood donors, outpatients with fever, anaemia, or sexually transmitted diseases, and antenatal clinic attenders in Mwanza Region, Tanzania?: AIDS. 1993 Apr;7(4):567-72. Unique Identifier : AIDSLINE MED/93283068; Borgdorff M; Barongo L; van Jaarsveld E; Klokke A; Senkoro K; Newell J; Nicoll A; Mosha F; Grosskurth H; Swai R; et al; National Institute for Medical Research, Mwanza, Tanzania.; OBJECTIVE: To assess the validity of extrapolation from sentinel data by comparing the HIV-1 prevalence of various sentinel groups with that of the general population in Mwanza Region, Tanzania . METHODS: In a population survey, 4161 individuals were selected in a stratified rando
Testing practices and spread of HIV among sexual partners of HIV-positive haemophiliacs in Italy. Gruppo Italiano Coagulopatie Congenite.: AIDS. 1993 Apr;7(4):573-7. Unique Identifier : AIDSLINE MED/93283069; Ghirardini A; Chiarotti F; Schinaia N; National AIDS Operational Centre, Istituto Superiore di Sanita,; Rome, Italy.; OBJECTIVES: To evaluate rates and predictors of testing and HIV positivity among the sexual partners of Italian HIV-positive haemophiliacs. METHODS: Our index cases were 602 sexually active HIV-positive haemophiliacs (aged 18 years or more) enrolled in the Italian Registry of Haemophilia. Data on the demographic and c
Multiple sexual partners: results of a national HIV/AIDS survey in the Central African Republic.: AIDS. 1993 Apr;7(4):579-83. Unique Identifier : AIDSLINE MED/93283070; Somse P; Chapko MK; Hawkins RV; Ministry of Public Health and Social Affairs, Bangui, Central; African Republic.; OBJECTIVES: To determine the prevalence and characteristics of individuals with more than one sexual partner in the Central African Republic during the previous 12 months. DESIGN: A national survey. METHODS: A stratified sample of 2589 individuals aged 15-50 years w
Further observations on zidovudine transfer and metabolism by human placenta [letter]: AIDS. 1993 Apr;7(4):590-2. Unique Identifier : AIDSLINE MED/93283073; Liebes L; Mendoza S; Lee JD; Dancis J
Secreting adrenal carcinoma in an HIV-infected patient [letter]: AIDS. 1993 Apr;7(4):594-5. Unique Identifier : AIDSLINE MED/93283076; Pedretti G; Magnani G; Guazzi AM; Nizzoli R; Fiaccadori F
HIV-related ocular microangiopathic syndrome and neuropsychological functioning [letter; comment]: AIDS. 1993 Apr;7(4):595-6. Unique Identifier : AIDSLINE MED/93283077; Perro C; Geier SA; Naber D; Klauss V; Kronawitter U; Bogner JR; Goebel ED
Decay of HIV-1 infectivity in whole blood, plasma and peripheral blood mononuclear cells [letter]: AIDS. 1993 Apr;7(4):596-7. Unique Identifier : AIDSLINE MED/93283078; Cao Y; Ngai H; Gu G; Ho DD
Clinical manifestation of HIV infection in northern Zaire [letter]: AIDS. 1993 Apr;7(4):597-8. Unique Identifier : AIDSLINE MED/93283079; Strecker W; Gurtler L; Binibangili M; Strecker K
Can prescribing policy influence patterns of drug taking and methods of drug administration? [letter]: AIDS. 1993 Apr;7(4):598-600. Unique Identifier : AIDSLINE MED/93283080; Haw S; Taylor A
[With a mandate to help (interview by Siv Barstad)]: J Sykepleien. 1993 May 4;81(8):14-5. Unique Identifier : AIDSLINE MED/93283205; Lauritzen HF
[Infection at the wheel]: J Sykepleien. 1993 May 18;81(9):20. Unique Identifier : AIDSLINE MED/93283218; Barstad S
Tuberculosis update.: J ET Nurs. 1993 Mar-Apr;20(2):20A. Unique Identifier : AIDSLINE MED/93283503; Morris J
Value of the polymerase chain reaction for the detection of Toxoplasma gondii in cerebrospinal fluid from patients with AIDS.: Clin Infect Dis. 1993 May;16(5):661-6. Unique Identifier : AIDSLINE MED/93283553; Schoondermark-van de Ven E; Galama J; Kraaijeveld C; van Druten J; Meuwissen J; Melchers W; Department of Medical Microbiology, University of Nijmegen, The; Netherlands.; To investigate whether the polymerase chain reaction (PCR) on the BI gene of Toxoplasma gondii could contribute to the diagnosis of cerebral toxoplasmosis in patients with AIDS, we retrospectively tested CSF samples from 20 patients with AIDS suspected of having cerebral toxoplasmosis for the presence of T. gondii. Su
Bacteremia due to Pseudomonas aeruginosa in children with AIDS.: Clin Infect Dis. 1993 May;16(5):706-8. Unique Identifier : AIDSLINE MED/93283559; Flores G; Stavola JJ; Noel GJ; Department of Pediatrics, Cornell University Medical College, New; York, New York.; Six episodes of Pseudomonas aeruginosa bacteremia in five children with AIDS were reviewed to characterize further the disease caused by this pathogen. Hypotension occurred in five episodes, and two children died. Bacteremia was associated most frequently with new pulmonary infiltrates and skin lesions, but additional
Tuberculous chest wall abscess in patients with AIDS [letter; comment]: Clin Infect Dis. 1993 May;16(5):727-8. Unique Identifier : AIDSLINE MED/93283566; Cacho G; Yebra M; Berrocal E; Ruiz J
Amyloidosis and infection due to human immunodeficiency virus [letter; comment]: Clin Infect Dis. 1993 May;16(5):733-4. Unique Identifier : AIDSLINE MED/93283571; Mery JP; Delahousse M; Nochy D
[Leishmania infection and AIDS]: An Med Interna. 1993 Jun;10 Suppl:29-33. Unique Identifier : AIDSLINE MED/93283601; Hernandez Quero J; Carvajal Becerra F; Escobar Lara T; Lopez Ruz MA; Velez Bernal ID; de La Higuera JM; Unidad de Enfermedades Infecciosas, Hospital Universitario,; Granada.
[Retrovirus and autoimmunity]: An Med Interna. 1993 Jun;10 Suppl:47-53. Unique Identifier : AIDSLINE MED/93283603; Coll J; Servicio de Medicina Interna, Hospital del Mar, Universidad; Autonoma, Barcelona.
Incidence of inhibitor development in a group of young hemophilia A patients treated exclusively with lyophilized cryoprecipitate.: Blood. 1993 Jun 15;81(12):3332-5. Unique Identifier : AIDSLINE MED/93283683; Peerlinck K; Rosendaal FR; Vermylen J; Center for Thrombosis and Vascular Research, University of; Leuven, Belgium.; The incidence of neutralizing isoantibody formation to infused factor VIII in a cohort of 67 hemophilia A patients, born between January 1, 1971 and April 30, 1990, who had been treated exclusively with lyophilized cryoprecipitate, was 6% (5.3 per 1,000 patient years of observation). The age-dependent cumulative risk
Identification of a novel human immunodeficiency virus strain cytopathic to megakaryocytic cells.: Blood. 1993 Jun 15;81(12):3336-42. Unique Identifier : AIDSLINE MED/93283684; Kunzi MS; Groopman JE; Mapplethorpe Laboratory for AIDS Research, Department of; Medicine, New England Deaconess Hospital, Harvard Medical School,; Boston, MA 02215.; Impaired megakaryocytopoiesis may be a contributing factor to thrombocytopenia associated with human immunodeficiency virus (HIV) infection. Because HIV isolates differ in their host range and pathogenicity, we investigated whether HIV strains with demonstrable cell tropism and increased cytopathicity for megakaryocyt
Dysmyelinating and demyelinating conditions in infancy.: Curr Opin Neurol Neurosurg. 1993 Jun;6(3):379-86. Unique Identifier : AIDSLINE MED/93283761; Kolodny EH; Department of Neurology, New York University School of Medicine,; NY 20016.; The myelin membrane is essential for rapid conduction of nerve impulses through the central nervous system. Failure of myelination--dysmyelination--may arise through several mechanisms. The synthesis of a particular myelin protein can be defective, as occurs for proteolipid protein in Pelizaeus-Merzbacher disease and
[Prevention of sexually transmitted diseases or control of prostitutes and patients with venereal diseases? An exemplary, epicritical study in Bremen]: Gesundheitswesen. 1993 Apr;55(4):179-84. Unique Identifier : AIDSLINE MED/93283871; Jager H; Patzelt I; Schmacke N; Hauptgesundheitsamt Bremen.; Data derived from laboratory and activity statistics of the Venereal Disease department of the Public Health Office in Bremen were analysed between 1961 and 1991. The traditional concept to fight venereal diseases aimed at controlling persons at risk for syphilis, gonorrhoea, chancroid or lymphogranuloma. This high-ri
Increasing incidence and mortality rates of soft tissue sarcoma in Western countries? [editorial]: Clin Investig. 1993 May;71(5):339-40. Unique Identifier : AIDSLINE MED/93283880; Schuurman B; Meyer S
Primary esophageal lymphoma in AIDS.: Abdom Imaging. 1993;18(3):223-4. Unique Identifier : AIDSLINE MED/93283997; Radin DR; Department of Radiology, University of Southern California School; of Medicine, L.A. County-USC Medical Center 90033.; In a patient with acquired immunodeficiency syndrome (AIDS) and primary esophageal lymphoma, esophagography and computed tomography (CT) demonstrated a large ulcerated mass involving the distal esophagus. Although rare, the diagnosis of esophageal lymphoma should be considered in patients at risk for AIDS when the rad
Exposure flow chart.: Nurs Qual Connect. 1993 May-Jun;2(6):4. Unique Identifier : AIDSLINE MED/93284146; Neid B
AIDS knowledge and risk behaviours among traumatic brain injury survivors with coexisting substance abuse.: Brain Inj. 1993 May-Jun;7(3):209-17. Unique Identifier : AIDSLINE MED/93284251; Kramer TH; Nelson DF; Li PW; Department of Psychiatry, State University of New York, Brooklyn.; An exploratory needs assessment for AIDS education and prevention was conducted at a traumatic brain injury (TBI) rehabilitation facility among 29 clients that also experience coexisting substance abuse disorders. The results suggest that the surveyed clients possessed a moderate level of information about AIDS. Their
Current problems in tuberculosis and its management.: Br J Hosp Med. 1993 May 5-18;49(9):645-8. Unique Identifier : AIDSLINE MED/93284337; Ormerod P; Blackburn Royal Infirmary, Lancashire.; The decline in tuberculosis (TB) incidence since 1950 stopped in the late 1980s, but the reasons for this arrest are not yet certain. An HIV/TB interaction, such as that described in the USA, has not yet been convincingly shown. Because of the decreased prevalence and variable distribution of TB cases, clinical awaren
HIV infection and Salmonella septic arthritis.: Clin Exp Rheumatol. 1993 Mar-Apr;11(2):187-9. Unique Identifier : AIDSLINE MED/93284767; Stein M; Houston S; Pozniak A; Kiire C; Mason PR; Department of Clinical Pharmacology, University of Zimbabwe; Medical School, Harare.; Human immunodeficiency virus (HIV) infection predisposes to bacterial infection at may sites but septic arthritis is notably uncommon. An HIV seropositive patient who presented with oligoarticular septic arthritis due to Salmonella enteritidis and who responded poorly to antibiotic therapy and repeated aspiration of i
Radionuclide hepatobiliary scanning in patients with AIDS-related sclerosing cholangitis.: Clin Nucl Med. 1993 May;18(5):417-22. Unique Identifier : AIDSLINE MED/93284786; Quinn D; Pocock N; Freund J; Kelleher A; Penny R; Brew B; Nuclear Medicine Department, St. Vincent's Hospital,; Darlinghurst, Australia.; Biliary disease, primarily manifesting as papillary stenosis or sclerosing cholangitis, is being increasingly recognized as a problem in the acquired immunodeficiency syndrome (AIDS) and may be amenable to specific treatment. Ultrasound, followed by endoscopic retrograde cholangiopancreatography (ERCP) for definitive
Intestinal mucosal inflammation associated with human immunodeficiency virus infection.: Dig Dis Sci. 1993 Jun;38(6):1119-27. Unique Identifier : AIDSLINE MED/93284975; Kotler DP; Reka S; Clayton F; Department of Medicine, St. Luke's-Roosevelt Hospital Center, New; York, New York 10025.; The role of the human immunodeficiency virus type-1 (HIV) in producing intestinal disease was studied prospectively in 74 HIV-infected individuals with (43) or without (31) the acquired immunodeficiency syndrome (AIDS). Thirty-one subjects had enteric infections; all but one had AIDS. Alteration in bowel habits was th
Splenic infarction associated with anticardiolipin antibodies in a patient with acquired immunodeficiency syndrome.: Dig Dis Sci. 1993 Jun;38(6):1152-5. Unique Identifier : AIDSLINE MED/93284980; Cappell MS; Simon T; Tiku M; Department of Medicine, UMDNJ-Robert Wood Johnson Medical School,; New Brunswick 08903-0019.; Although patients with AIDS frequently develop high titers of anticardiolipin antibodies, the clinical significance of this laboratory abnormality in AIDS patients is unknown. A 33-year-old female with AIDS, a prior small cerebrovascular accident, thrombocytopenia, and a coagulopathy suddenly developed left upper quad
The lux autoinducer regulates the production of exoenzyme virulence determinants in Erwinia carotovora and Pseudomonas aeruginosa.: EMBO J. 1993 Jun;12(6):2477-82. Unique Identifier : AIDSLINE MED/93285118; Jones S; Yu B; Bainton NJ; Birdsall M; Bycroft BW; Chhabra SR; Cox AJ; Golby P; Reeves PJ; Stephens S; et al; Department of Biological Sciences, University of Warwick,; Coventry, UK.; Erwinia carotovora and Pseudomonas aeruginosa secrete exoenzymes that contribute to the pathogenesis of plant and mammalian infections respectively. E.carotovora mutants defective in synthesis of the pectinase, cellulase and protease exoenzymes were isolated and classified into two groups. Group 2 mutants were found t
Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters.: EMBO J. 1993 Jun;12(6):2539-48. Unique Identifier : AIDSLINE MED/93285125; Eggermont J; Proudfoot NJ; Sir William Dunn School of Pathology, University of Oxford, UK.; Transcriptional termination by RNA polymerase II at the 3 end of genes encoding poly(A)+ mRNAs is thought to require two distinct cis-active elements: a functional poly(A) signal and a downstream transcriptional pause site. An important requirement for efficient termination is to prevent transcriptional interference
Cervical intraepithelial neoplasia in HIV seropositive patients.: Eur J Gynaecol Oncol. 1993;14(3):246-8. Unique Identifier : AIDSLINE MED/93285256; Gentile G; Formelli G; Costigliola P; Busacchi P; Pelusi G; Inst. Obstet. Gynecol. Clinic, University of Bologna.; In order to assess the frequency of cervical intraepithelial neoplasia (CIN) in a high risk population, 32 women infected with human immunodeficiency virus (HIV), with no AIDS-related symptoms, underwent colposcopic, cytologic and histologic examinations of the uterine cervix. In seven cases (21.9%) cervical smears sh
HIV: what employers need to know [news]: Fla Nurse. 1993 May;41(5):2. Unique Identifier : AIDSLINE MED/93285370
Developing AIDS community service consortia.: Health Aff (Millwood). 1993 Spring;12(1):186-99. Unique Identifier : AIDSLINE MED/93285571; Mor V; Fleishman JA; Piette JD; Allen SM; Brown University Center for Gerontology and Health Care Research.
Clinico-epidemiological study of donovanosis in Durban, South Africa.: Genitourin Med. 1993 Apr;69(2):108-11. Unique Identifier : AIDSLINE MED/93285651; O'Farrell N; City Health STD Clinic, King Edward VIII Hospital, Durban, Natal,; South Africa.; OBJECTIVE: To describe the epidemiological and clinical features of donovanosis and their relevance to the possible coincident risk of HIV-1 transmission in patients attending an STD clinic. DESIGN: Assessment of patients with donovanosis diagnosed by the detection of Donovan bodies on tissue smears stained by the Rap
Management of genital herpes by genitourinary physicians: does experience or doctor's gender influence clinical management?: Genitourin Med. 1993 Apr;69(2):115-8. Unique Identifier : AIDSLINE MED/93285653; Russell JM; Cracknell M; Barton SE; Catalan J; Department of Genitourinary Medicine, Charing Cross Hospital,; London, UK.; OBJECTIVE--To determine the variation in management of genital herpes by genitourinary physicians, and whether their duration of experience or gender influence their clinical management. METHODS--A postal questionnaire was sent to UK consultant genitourinary physicians with deta
Systemic Pneumocystis carinii pneumonia prophylaxis with dapsone and pyrimethamine fails to protect against extrapulmonary pneumocystosis.: Genitourin Med. 1993 Apr;69(2):130-2. Unique Identifier : AIDSLINE MED/93285657; Carlin EM; Coker RJ; Goldin RD; Harris JR; Department of Genitourinary Medicine, St. Mary's Hospital,; London, UK.; Extrapulmonary pneumocystosis is a feature of severe immunosuppression which earlier reports have suggested is limited to patients receiving either no prophylaxis or aerosolised pentamidine. We report a case of disseminated pneumocystosis which developed in an HIV positive homosexual man despite systemic primary Pneum
Adolescents, sexual behaviour and implications for an epidemic of HIV/AIDS among the young.: Genitourin Med. 1993 Apr;69(2):133-40. Unique Identifier : AIDSLINE MED/93285658; Dickson N; Paul C; Herbison P; Department of Preventive and Social Medicine, University of Otago; Medical School, Dunedin, New Zealand.; OBJECTIVE--To determine the patterns of sexual behaviour, condom use and sexually transmitted diseases among young New Zealanders, and the characteristics of those with many sexual partners. SUBJECTS--A cohort of young people enrolled in a longitudinal cohort study, and followed up since age three. METHODS--Subjects w
A history of sexually transmitted diseases in Thailand: policy and politics.: Genitourin Med. 1993 Apr;69(2):148-57. Unique Identifier : AIDSLINE MED/93285660; Bamber SD; Hewison KJ; Underwood PJ; University of Western Australia.; This paper provides a brief history of sexually transmitted diseases (STDs) in Thailand . The presentation is divided into three main sections: the period up to the 1930s; the period from the 1930s until the end of the early 1980s; and the period from the early 1980s until the pre
Partner notification for HIV infection in the United Kingdom: a look back on seven years experience in Newcastle upon Tyne.: Genitourin Med. 1993 Apr;69(2):94-7. Unique Identifier : AIDSLINE MED/93285664; Pattman RS; Gould EM; Department of Genitourinary Medicine, Newcastle General Hospital,; Newcastle upon Tyne, UK.; OBJECTIVE--To examine the outcome of partner notification for HIV infection. DESIGN--Retrospective analysis of medical, health adviser and counsellor records. SETTING--Teaching hospital, Newcastle upon Tyne. PATIENTS--All newly diagnosed cases of human immunodeficiency virus (HIV) infection and their sexual partners.
The role of CD8-positive lymphocytes in the control of HIV-1 infection of peripheral blood mononuclear cells.: Immunol Lett. 1993 Feb;35(2):83-92. Unique Identifier : AIDSLINE MED/93285742; Bagasra O; Pomerantz RJ; Thomas Jefferson University, Jefferson Medical College,; Department of Medicine, Philadelphia, PA 19107.; The role of CD8-positive lymphocytes from HIV-1-seropositive individuals in the inhibition of HIV-1 replication in CD4-positive lymphocytes, either from HIV-1-seropositive or seronegative individuals, has been described. It has been suggested that CD8-positive lymphocytes isolated from HIV-1-seropositive individuals a
Lymphokine induction of rat microglia multinucleated giant cell formation.: Glia. 1993 May;8(1):51-61. Unique Identifier : AIDSLINE MED/93285781; Lee TT; Martin FC; Merrill JE; Department of Neurology, Reed Neurological Research Center, UCLA; School of Medicine 90024-1769.; Multinucleated giant cell formation (MNGC) occurs in central nervous system AIDS. The mechanism of fusion of microglia in these cases is unknown. We investigated the ability of lymphokines to induce fusion and found that interleukin-3 (IL-3), interleukin-4 (IL-4), gamma interferon (gamma-IFN), and granulocyte-macropha
The optimization of hearing-impaired children's speechreading.: Int J Pediatr Otorhinolaryngol. 1993 Apr;26(3):209-23. Unique Identifier : AIDSLINE MED/93285880; Arnold P; Department of Psychology, University of Manchester, UK.; As more hearing-impaired and deaf children are mainstreamed into regular schools and as age related hearing loss in advanced countries become more prevalent, so the need for optimal methods to teach speechreading increases. The numbers of children and adults who would benefit from improved methods of teaching speechre
Policy regarding HIV-infected health care workers.: Iowa Med. 1993 May;83(5):184-5. Unique Identifier : AIDSLINE MED/93285907
Predictive value of neurological abnormalities in HIV 1 patients in the early stages of the infection.: Ital J Neurol Sci. 1993 Mar;14(2):171-7. Unique Identifier : AIDSLINE MED/93285917; Tilia G; Spadaro M; Soldati G; Pinter E; Morocutti C; Istituto di Clinica delle Malattie Nervose e Mentali, Universita; La Sapienza, Roma.; A longitudinal clinical neurological and electrophysiological follow-up study was carried out on 31 HIV1 seropositive outpatients in the asymptomatic or LAS stages of the infection (CDC II-III). The results of clinical examination and multimodal evoked potentials (EP) recording showed a high percentage of abnormalitie
Antiviral therapy of chronic hepatitis B: past, present, and future.: J Hepatol. 1993;17 Suppl 3:S56-63. Unique Identifier : AIDSLINE MED/93286415; Perrillo RP; Washington University School of Medicine, St. Louis, MO.; A wide variety of agents has been used to treat chronic hepatitis B, but none has proved effective with the exception of interferon. Toxicity has been a major problem with some drugs whereas in others a lack of antiviral potency has been demonstrated. Alpha-interferon represents a good compromise because it has both i
Simian immunodeficiency virus (SIVmac251) membrane lipid mixing with human CD4+ and CD4- cell lines in vitro does not necessarily result in internalization of the viral core proteins and productive infection.: J Gen Virol. 1993 Jun;74 ( Pt 6):1043-54. Unique Identifier : AIDSLINE MED/93286558; Stamatatos L; Duzgunes N; Department of Microbiology, University of the Pacific School of; Dentistry, San Francisco, California 94115-2399.; The cell binding site of simian immunodeficiency virus (SIV) is believed to be the CD4 molecule. Several CD4+ cell lines are, however, resistant to infection by SIVmac251 in vitro and additional cell membrane molecules have been implicated in SIVmac251 entry. We investigated the binding, envelope fusion and entry of t
Optic neuritis and HIV-1 infection.: J Neurol Neurosurg Psychiatry. 1993 Jun;56(6):705-7. Unique Identifier : AIDSLINE MED/93286618; Sweeney BJ; Manji H; Gilson RJ; Harrison MJ; Department of Genito-Urinary Medicine, University College and; Middlesex School of Medicine, London, UK.; A patient is reported who developed acute optic neuritis in the context of severe immunodeficiency associated with HIV-1 infection. The clinical, laboratory, and radiological features are described and the possible associations with syphilis, multiple sclerosis, lymphoma, and HIV-1 infection are discussed.
Occurrence of primary biliary cirrhosis, CREST syndrome and Sjogren's syndrome in a patient with HTLV-I-associated myelopathy.: J Neurol Sci. 1993 May;116(1):47-51. Unique Identifier : AIDSLINE MED/93286636; Kuroda Y; Fukuoka M; Endo C; Matsui M; Kurohara K; Kakigi R; Tokunaga O; Department of Internal Medicine (Section of Neurology), Saga; Medical School, Japan.; We report the occurrence of three autoimmune diseases (primary biliary cirrhosis, CREST syndrome and Sjogren s syndrome) in a patient with HTLV-I-associated myelopathy (HAM). The patient had the depressed cell-mediated immune responses but the infiltration of CD8-T cells was found in the cerebrospinal fluid and liver.
Uncommon invasive fungal pathogens in the acquired immunodeficiency syndrome.: J Med Vet Mycol. 1993;31(2):175-9. Unique Identifier : AIDSLINE MED/93286846; Perfect JR; Schell WA; Rinaldi MG; Department of Medicine, Duke University Medical Center, Durham,; NC 27710.; This communication lists fungi reported to cause invasive infection in patients with AIDS. It excludes the well known and common fungi that infect these patients such as Candida, Cryptococcus, Histoplasma, Coccidioides and Aspergillus. It is likely that these less common fungal pathogens will be seen more frequently i
Pentoxifylline inhibits HIV-1 LTR-driven gene expression by blocking NF-kappa B action.: J Acquir Immune Defic Syndr. 1993 Jul;6(7):778-86. Unique Identifier : AIDSLINE MED/93286875; Biswas DK; Dezube BJ; Ahlers CM; Pardee AB; Division of Cell Growth and Regulation, Dana-Farber Cancer; Institute, Boston, MA 02115.; The drug pentoxifylline (PTX) (1-(5 -oxohexyl) 3,7-dimethylxanthine) down-regulates human immunodeficiency virus (HIV-1) long terminal repeat (LTR)-directed gene expression in the human monocytic cell line U38. This effect of PTX has been tested in clinical trials. In this investigation, a similar inhibitory effect of
Psychological effects of participation and nonparticipation in a placebo-controlled zidovudine clinical trial with asymptomatic human immunodeficiency virus-infected individuals.: J Acquir Immune Defic Syndr. 1993 Jul;6(7):795-808. Unique Identifier : AIDSLINE MED/93286877; Robiner WN; Melroe NH; Campbell S; Rhame FS; Colon E; Chung J; Reaney S; Health Psychology Clinic, University of Minnesota Hospital and; Clinic, Minneapolis 55455.; Psychological effects of participation in Protocol 019, a zidovudine placebo-controlled clinical trial, were investigated. Forty-six Protocol 019 subjects and 27 control asymptomatic human immunodeficiency virus-seropositive subjects were assessed at entry, 2 months, 6 months, and after trial modification. At baseline
Variability of reporting and lack of adherence to consensus guidelines in human T-lymphocyte immunophenotyping reports: results of a case series.: J Acquir Immune Defic Syndr. 1993 Jul;6(7):823-30. Unique Identifier : AIDSLINE MED/93286880; Peddecord KM; Benenson AS; Hofherr LK; Francis DP; Garfein RS; Cross GD; Schalla WO; Laboratory Assurance Program, Graduate School of Public Health,; College of Health and Human Services, San Diego State University,; CA 92182-0405.; Percentages and absolute counts of CD4+ lymphocytes, as determined by T-lymphocyte immunophenotyping (TLI), are prognostic, as well as diagnostic, of the course of human immunodeficiency virus type 1 infections and are important indicators for initiating Pneumocystis carinii pneumonia prophylaxis and antiretroviral th
The effects of intravenous drug use and gender on the cost of hospitalization for patients with AIDS [see comments]: J Acquir Immune Defic Syndr. 1993 Jul;6(7):831-9. Unique Identifier : AIDSLINE MED/93286881; Seage GR 3d; Hertz T; Stone VE; Epstein AM; Institute for Urban Health Policy, Research and Education, Boston; Department of Health and Hospital, MA 02118.; At present limited data exist describing the hospital use patterns of intravenous drug users (IVDUs) and women with AIDS. Our objective was to determine if frequency of hospitalization, length of stay (LOS), and cost per hospitalization varied by risk status and gender, controlling for a variety of confounders, includ
The risk of tropical spastic paraparesis differs according to ethnic group among HTLV-I carriers in Inongo, Zaire.: J Acquir Immune Defic Syndr. 1993 Jul;6(7):840-4. Unique Identifier : AIDSLINE MED/93286882; Jeannel D; Garin B; Kazadi K; Singa L; de The G; Unite d'Epidemologie des Virus Oncogenes and URA 1157 CNRS,; Institut Pasteur, Paris, France.; Following the finding in 1990 of six HTLV-I-positive cases of tropical spastic paraparesis (TSP/HAM) is a field survey carried out in the city of Inongo (Bandundu, Zaire ), the prevalence of HTLV-I infection has been studied by detection of specific antibodies on a randomized sampl
No change in incidence and prevalence of HIV among intravenous drug users in Copenhagen from 1985 to 1990.: J Acquir Immune Defic Syndr. 1993 Jul;6(7):845-8. Unique Identifier : AIDSLINE MED/93286883; Worm AM; Gottschau A; University of Copenhagen, Department of Dermatology and; Venereology, Bispebjerg Hospital, Denmark.; During the years 1984 to 1990, 1,029 intravenous drug users (IVDU), equalling approximately one-third of the estimated total IVDU population in the study area, attended the outpatient venereal disease clinic of Copenhagen for an HIV antibody test. Neglecting samples on HIV-positive persons after the first positive tes
Cutaneous nocardiosis caused by Nocardia nova occurring in an HIV-infected individual: a case report and review of the literature [letter]: J Acquir Immune Defic Syndr. 1993 Jul;6(7):849-51. Unique Identifier : AIDSLINE MED/93286884; Schiff TA; Sanchez M; Moy J; Klirsfeld D; McNeil MM; Brown JM
Presence of human T-cell lymphotropic virus types I and II and coinfection with human immunodeficiency virus in different groups at risk in Argentina [letter]: J Acquir Immune Defic Syndr. 1993 Jul;6(7):851-2. Unique Identifier : AIDSLINE MED/93286885; Pampuro SE; Rabinovich RD; Martinez Peralta L; Gallo D; Hanson C; Libonatti O
Zidovudine treatment and virus excretion in the cervicovaginal secretions of HIV-infected women [letter]: J Acquir Immune Defic Syndr. 1993 Jul;6(7):852-4. Unique Identifier : AIDSLINE MED/93286886; Nicolosi A
TB on the rise in the U.S. [news]: J Pract Nurs. 1993 Mar;43(1):19. Unique Identifier : AIDSLINE MED/93286961
GroupBuild: a fragment-based method for de novo drug design.: J Med Chem. 1993 Jun 11;36(12):1700-10. Unique Identifier : AIDSLINE MED/93287039; Rotstein SH; Murcko MA; Vertex Pharmaceuticals Incorporated, Cambridge, Massachusetts; 02139-4211.; A novel method for de novo drug design, GroupBuild, has been developed to suggest chemically reasonable structures which fill the active sites of enzymes. The proposed molecules provide good steric and electrostatic contact with the enzyme and exist in low-energy conformations. These structures are composed entirely o
Divergent evolution may link human immunodeficiency virus GP41 to human CD4.: J Mol Evol. 1993 May;36(5):448-57. Unique Identifier : AIDSLINE MED/93287142; Facchiano A; Facchiano F; van Renswoude J; Raggio Italgene S.p.A., Pomezia, Roma, Italy.; A local sequence similarity of HIV envelope proteins (gp120 and gp41) to immunoglobulins suggests that a mimicry phenomenon may form the basis of the HIV-cell membrane interaction and of HIV-induced autoimmune reaction. We explored the hypothesis of any deeper relationship between HIV env proteins and immunoglobulin f
The full-length Tat protein is required for TAR-independent, posttranscriptional trans activation of human immunodeficiency virus type 1 env gene expression.: J Virol. 1993 Jul;67(7):3739-47. Unique Identifier : AIDSLINE MED/93287187; Kim YS; Panganiban AT; McArdle Laboratory for Cancer Research, University of Wisconsin,; Madison 53706.; Tat is a protein that dramatically increases the expression of all genes expressed from the human immunodeficiency virus type 1 (HIV-1) long terminal repeat through interaction with a cis-acting target sequence referred to as TAR (for trans-acting responsive region). The tat gene is divided into two coding exons which
A direct demonstration of recombination between an injected virus and endogenous viral sequences, resulting in the generation of mink cell focus-inducing viruses in AKR mice.: J Virol. 1993 Jul;67(7):3763-70. Unique Identifier : AIDSLINE MED/93287190; DiFronzo NL; Holland CA; Center for Virology, Children's National Medical Center,; Washington, DC 20010-2970.; We analyzed viral recombination events that occur during the preleukemic period in AKR mice. We tagged a molecular chimera between the nonleukemogenic virus Akv and the leukemogenic mink cell focus-inducing (MCF) virus MCF 247 with an amber suppressor tRNA gene, supF. We injected the supF-tagged chimeric virus that co
Physicochemical dissociation of CD4-mediated syncytium formation and shedding of human immunodeficiency virus type 1 gp120.: J Virol. 1993 Jul;67(7):3818-25. Unique Identifier : AIDSLINE MED/93287196; Fu YK; Hart TK; Jonak ZL; Bugelski PJ; SmithKline Beecham Pharmaceuticals, Toxicology-U.S., King of; Prussia, Pennsylvania 19406-0939.; The mechanism of CD4-mediated fusion via activated human immunodeficiency virus type 1 (HIV-1) gp41 and the biological significance of soluble CD4 (sCD4)-induced shedding of gp120 are poorly understood. The purpose of these investigations was to determine whether shedding of gp120 led to fusion activation or inactivat
Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro: the cytoplasmic domain of CD4 contributes to Vpu sensitivity.: J Virol. 1993 Jul;67(7):3877-84. Unique Identifier : AIDSLINE MED/93287203; Chen MY; Maldarelli F; Karczewski MK; Willey RL; Strebel K; Laboratory of Molecular Microbiology, National Institute of; Allergy and Infectious Diseases, Bethesda, Maryland 20892.; CD4 is an integral membrane glycoprotein which functions as the human immunodeficiency virus (HIV) receptor for infection of human host cells. We have recently demonstrated that Vpu, an HIV type 1 (HIV-1) encoded integral membrane phosphoprotein, induces rapid degradation of CD4 in the endoplasmic reticulum. In this r
Independent variation and positive selection in env V1 and V2 domains within maternal-infant strains of human immunodeficiency virus type 1 in vivo.: J Virol. 1993 Jul;67(7):3951-60. Unique Identifier : AIDSLINE GENBANK/L15087; Lamers SL; Sleasman JW; She JX; Barrie KA; Pomeroy SM; Barrett DJ; Goodenow MM; Department of Pathology and Laboratory Medicine, University of; Florida College of Medicine, Gainesville 32610-0275.; Multiple targets for immune recognition and cellular tropism are localized to the V1 and V2 hypervariable regions in the amino portion of human immunodeficiency virus type 1 (HIV-1) gp120env. We have assessed genetic diversity in env V1 and V2 hypervariable domains in vivo within epidemiologically related strains of H
Packaging of human immunodeficiency virus type 1 RNA requires cis-acting sequences outside the 5' leader region.: J Virol. 1993 Jul;67(7):3997-4005. Unique Identifier : AIDSLINE MED/93287217; Richardson JH; Child LA; Lever AM; Department of Medicine, University of Cambridge, Addenbrooke's; Hospital, United Kingdom.; cis elements required for the encapsidation of human immunodeficiency virus type 1 (HIV-1) RNA have been investigated by using a replication-competent helper virus to package a series of HIV-1-based vectors which had been stably transfected into human CD4 T-cell lines. A previously identified packaging signal in the 5
The two zinc fingers in the human immunodeficiency virus type 1 nucleocapsid protein are not functionally equivalent.: J Virol. 1993 Jul;67(7):4027-36. Unique Identifier : AIDSLINE MED/93287220; Gorelick RJ; Chabot DJ; Rein A; Henderson LE; Arthur LO; AIDS Vaccine Development Program, Program Resources Inc.,; DynCorp, Frederick, Maryland.; The highly conserved zinc fingers in retroviral nucleocapsid (NC) proteins have the general structure Cys-(X)2-Cys-(X)4-His-(X)4-Cys. Human immunodeficiency virus type 1 (HIV-1) contains two Zn2+ fingers, and mutants were constructed in which the native sequence of each Zn2+ finger was maintained but their positions i
Partial inhibition of the human immunodeficiency virus type 1 protease results in aberrant virus assembly and the formation of noninfectious particles.: J Virol. 1993 Jul;67(7):4050-5. Unique Identifier : AIDSLINE MED/93287222; Kaplan AH; Zack JA; Knigge M; Paul DA; Kempf DJ; Norbeck DW; Swanstrom R; Department of Medicine, University of North Carolina, Chapel Hill; 27599-7295.; The production of infectious particles by human immunodeficiency virus type 1 is dependent on the accurate cleavage of its Gag and Gag/Pol precursors by a virally encoded protease. In the absence of protease activity, morphologically abnormal particles which are noninfectious are formed. Recently, inhibitors of the pr
Characterization of a naturally occurring ecotropic receptor that does not facilitate entry of all ecotropic murine retroviruses.: J Virol. 1993 Jul;67(7):4056-61. Unique Identifier : AIDSLINE MED/93287223; Eiden MV; Farrell K; Warsowe J; Mahan LC; Wilson CA; Laboratory of Cell Biology, National Institute of Mental Health,; Bethesda, Maryland 20892.; A fibroblast cell line (MDTF) derived from the feral mouse Mus dunni is resistant to infection by Moloney murine leukemia virus (Mo-MuLV), an ecotropic murine leukemia virus (E-MuLV) (M. R. Lander and S. K. Chattopadadhyay, J. Virol. 52:695-698, 1984). MDTF cells can be infected by other E-MuLVs such as Friend MuLV an
Simian immunodeficiency virus mutants resistant to serum neutralization arise during persistent infection of rhesus monkeys.: J Virol. 1993 Jul;67(7):4104-13. Unique Identifier : AIDSLINE GENBANK/M61092; Burns DP; Collignon C; Desrosiers RC; New England Regional Primate Research Center, Harvard Medical; School, Southborough, Massachusetts 01772-9102.; We previously described the pattern of sequence variation in gp120 following persistent infection of rhesus monkeys with the pathogenic simian immunodeficiency virus SIVmac239 molecular clone (D.P.W. Burns and R.C. Desrosiers, J. Virol. 65:1843, 1991). Sequence changes were confined largely to five variable regions (V
Transgenic Fv-4 mice resistant to Friend virus.: J Virol. 1993 Jul;67(7):4163-8. Unique Identifier : AIDSLINE MED/93287235; Limjoco TI; Dickie P; Ikeda H; Silver J; Laboratory of Molecular Microbiology, National Institute of; Allergy and Infectious Diseases, Bethesda, Maryland 20892.; Fv-4 is a mouse gene that confers resistance to infection with ecotropic retroviruses. A candidate Fv-4 gene was cloned previously and found to resemble the 3 half of a murine leukemia virus (MuLV). To study the effect of this gene in vivo, we generated two transgenic mouse strains carrying the Fv-4 env gene under co
Human immunodeficiency virus type 1 Vpu has a CD4- and an envelope glycoprotein-independent function.: J Virol. 1993 Jul;67(7):4190-4. Unique Identifier : AIDSLINE MED/93287238; Geraghty RJ; Panganiban AT; McArdle Laboratory for Cancer Research, University of Wisconsin,; Madison 53706.; Vpu is a 16-kDa membrane-associated phosphoprotein that is expressed from the same, singly spliced message as the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein precursor, gp160. Previous studies suggest that Vpu functions in the late stages of viral replication, possibly in virus egression from the
Differential expression of Rel family members in human T-cell leukemia virus type I-infected cells: transcriptional activation of c-rel by Tax protein.: J Virol. 1993 Jul;67(7):4205-13. Unique Identifier : AIDSLINE MED/93287240; Li CC; Ruscetti FW; Rice NR; Chen E; Yang NS; Mikovits J; Longo DL; Biological Carcinogenesis and Development Program, Program; Resources, Inc./Dyncorp, Frederick, Maryland.; The Tax protein of the human T-cell leukemia virus type I (HTLV-I) has been shown to induce nuclear expression of Rel family NF-kappa B-binding proteins. However, under different experimental conditions, different J. H. Kim, Y. Daitoku, and W. G. Greene, J. Virol. 65:6892-6899, 1991). In this study, using specific imm
Vpx of simian immunodeficiency virus is localized primarily outside the virus core in mature virions.: J Virol. 1993 Jul;67(7):4386-90. Unique Identifier : AIDSLINE MED/93287261; Yu X; Matsuda Z; Yu QC; Lee TH; Essex M; Department of Cancer Biology, Harvard School of Public Health,; Boston, Massachusetts 02115.; Human immunodeficiency virus type 2 and the related simian immunodeficiency virus (SIV) contain a unique regulatory gene, vpx. The Vpx protein is packaged in mature virions and is required for efficient viral replication in peripheral blood lymphocytes and macrophages. To study the localization of Vpx in mature virion
Antisense phosphorothioate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages.: J Virol. 1993 Jul;67(7):4409-14. Unique Identifier : AIDSLINE MED/93287266; Balotta C; Lusso P; Crowley R; Gallo RC; Franchini G; Laboratory of Tumor Cell Biology, National Cancer Institute,; Bethesda, Maryland 20892.; The replication of human immunodeficiency viruses (HIV) in human macrophages is influenced by genetic determinants which have been mapped predominantly to the viral envelope. However, in HIV-2, the vpr gene has also been suggested as an important modulator of viral expression in human macrophages. We synthesized five
Phorbol esters modulate the phosphorylation of human T-cell leukemia virus type I Tax.: J Virol. 1993 Jul;67(7):4436-41. Unique Identifier : AIDSLINE MED/93287271; Fontes JD; Strawhecker JM; Bills ND; Lewis RE; Hinrichs SH; Department of Pathology, University of Nebraska Medical Center,; Omaha 68198-6495.; The Tax protein from human T-cell leukemia virus type I (HTLV-I) is a 40-kDa phosphoprotein capable of activating transcription from its own long terminal repeat (LTR), as well as increasing the transcription of cellular genes. Transcriptional activation of the HTLV-I LTR has been demonstrated via a cyclic-AMP-respons
Differential regulation of the human immunodeficiency virus type 2 enhancer in monocytes at various stages of differentiation.: J Virol. 1993 Jul;67(7):4448-53. Unique Identifier : AIDSLINE MED/93287273; Hilfinger JM; Clark N; Smith M; Robinson K; Markovitz DM; Department of Internal Medicine, University of Michigan Medical; Center, Ann Arbor 48109-0680.; We have demonstrated that stimulation of the human immunodeficiency virus type 2 (HIV-2) enhancer in T cells is dependent upon at least four cis-acting elements, including two purine-rich binding sites, PuB1 and PuB2, which are capable of binding members of the ets family of proto-oncogenes, the pets (peri-ets) site,
The management of meatal obstruction due to Kaposi's sarcoma of the glans penis.: J Urol. 1993 Jul;150(1):193-5. Unique Identifier : AIDSLINE MED/93287301; Swierzewski SJ 3d; Wan J; Boffini A; Faerber GJ; Department of Surgery, University of Michigan Medical Center, Ann; Arbor.; Kaposi s sarcoma involving the glans penis was first described in 1902, with a subsequent report of meatal disease in 1943. With the recognition of the acquired immunodeficiency syndrome, genital lesions are becoming more frequently reported, with 51 cases cited in the literature. To date only 4 additional cases of me
'Invisible' epidemic now becoming visible as HIV/AIDS pandemic reaches adolescents [news]: JAMA. 1993 Jul 7;270(1):16, 18-9. Unique Identifier : AIDSLINE MED/93287344; Goldsmith MF
[Current status of transfusion-transmitted infection]: Rinsho Ketsueki. 1993 Apr;34(4):411-7. Unique Identifier : AIDSLINE MED/93287394; Shimizu M; Department of Transfusion Medicine, Tokyo Women's Medical; College.; Recently transfusion-transmitted infections (TTI) have been decreased remarkably. Especially nonA, nonB posttransfusion hepatitis (PTH) has reduced to one third by introducing anti-HCV (C100-3) antibody screening. HCV-PTH will be lowered more with screening by the 2nd generation reagent of HCV. None of cases with HIV
HIV and AIDS: a review of the recent MMWR literature.: J Emerg Nurs. 1993 Jun;19(3):249-53. Unique Identifier : AIDSLINE MED/93287440; Danis DM
Saving the ethnopharmacological heritage of Samoa.: J Ethnopharmacol. 1993 Mar;38(2-3):181-8. Unique Identifier : AIDSLINE MED/93287679; Cox PA; Department of Botany, Brigham Young University, Provo, Utah; 84602.; Early European visitors to Samoa tended to denigrate the authenticity and efficacy of Samoan herbal medicine, yet bioassays indicate pharmacological activity in over 86% of Samoan medicinal plants. Novel anti-inflammatory compounds
[AIDS 1992. New definition, new classification (letter)]: Med Clin (Barc). 1993 Jun 5;101(2):76. Unique Identifier : AIDSLINE MED/93287695; Pena JM; Vazquez JJ
Human immunodeficiency virus type 1 (HIV-1) tat-protein stimulates the production of interleukin-6 (IL-6) by peripheral blood monocytes.: New Microbiol. 1993 Apr;16(2):115-20. Unique Identifier : AIDSLINE MED/93287893; Zauli G; Furlini G; Re MC; Milani D; Capitani S; La Placa M; Institute of Human Anatomy, University of Ferrara, Italy.; In this study we evaluated the effect of human immunodeficiency virus type 1 (HIV-1) recombinant tat-protein on the production of interleukin-6 (IL-6), granulocyte/macrophage colony stimulating factor (GM-CSF) and tumor necrosis factor-alpha (TNF-alpha) by purified peripheral blood monocytes. Whereas no effects were o
A simple method to detect HIV-1 protein specificity of IgG intrathecal synthesis in HIV-1 infection.: New Microbiol. 1993 Apr;16(2):121-7. Unique Identifier : AIDSLINE MED/93287894; Carbonara S; Angarano G; Quarto M; Germinario C; Chironna M; Fiore JR; Monno L; Barbuti S; Pastore G; Clinic of Infectious Diseases, University of Bari, Italy.; There is currently no simple method to detect the antigen specificity of anti-HIV-1 IgG intrathecal synthesis (IS). Fifty-seven pairs of serum and corresponding CSF from 29 HIV-1 seropositive patients were adjusted to an identical concentration of total IgG and tested by a commercial HIV-1 Western Blot (WB) assay. IgG
Booster PCR: evaluation of an improved method for amplification of a few HIV-1 proviral DNA sequences.: New Microbiol. 1993 Apr;16(2):129-33. Unique Identifier : AIDSLINE MED/93287895; Filice G; Debiaggi M; Cereda PM; Romero E; Institute of Infectious Diseases, University of Pavia, IRCCS San; Matteo, Italy.; A biphasic polymerase chain reaction designed as booster PCR for the detection of human immunodeficiency virus type-1 (HIV-1) was evaluated in samples containing a very low number of target DNA. We examined DNA samples obtained from chronically infected H9/HTLV-III B cells and purified plasmidic DNA containing the ent
Polymerase chain reaction in the early diagnosis of HIV-1 infection in high risk subjects.: New Microbiol. 1993 Apr;16(2):181-4. Unique Identifier : AIDSLINE MED/93287902; Borghi V; Lami G; Frigieri G; Cecchi MT; Zoboli G; Tavio M; Pecorari M; Mongiardo N; Cossarizza A; De Rienzo B; Department of Infectious and Tropical Diseases, University of; Modena, Italy.; We investigated the presence of the HIV-1 infection using the polymerase chain reaction (PCR) test in seronegative sexual partners of HIV-infected subjects and in children born to seropositive mothers. By using PCR assay, no HIV-1 DNA was detected in 32 female partners of HIV positive patients including three pregnant
HIV-infected health care workers [news]: Midwives Chron. 1993 May;106(1264):164. Unique Identifier : AIDSLINE MED/93287916
HIV transmission [letter]: Midwives Chron. 1993 May;106(1264):184. Unique Identifier : AIDSLINE MED/93287921; Kennedy J
HIV transmission [letter]: Midwives Chron. 1993 May;106(1264):184. Unique Identifier : AIDSLINE MED/93287922; Pritchard M
Midwives to get new safety guidelines on the twin dangers of HIV and hepatitis B [news]: Midwives Chron. 1993 May;106(1264):186. Unique Identifier : AIDSLINE MED/93287923
Pediatric AIDS--Johns Hopkins grand rounds.: Neonatal Netw. 1993 Jun;12(4):7-15. Unique Identifier : AIDSLINE MED/93287960; Oleske J
Update: mortality attributable to HIV infection/AIDS among persons aged 25-44 years--United States, 1990 and 1991.: MMWR Morb Mortal Wkly Rep. 1993 Jul 2;42(25):481-6. Unique Identifier : AIDSLINE MED/93287968; During the 1980s, human immunodeficiency virus (HIV) infection emerged as a leading cause of death in the United States . This report updates national trends in deaths caused by HIV infection during 1990 and 1991 and indicates that HIV infection/acquired immunodeficiency syndrome (AIDS)
Drug-resistant tuberculosis in New York City [letter; comment]: N Engl J Med. 1993 Jul 8;329(2):134-5. Unique Identifier : AIDSLINE MED/93288070; Israel HL
Using saliva to test for HIV.: Nurs RSA. 1993 Mar;8(3):35. Unique Identifier : AIDSLINE MED/93288117
Opportunistic infection [letter]: Nature. 1993 Jun 17;363(6430):577. Unique Identifier : AIDSLINE MED/93288124; Leavitt FJ
AIDS update. What to tell patients about the female condom.: Nursing. 1993 Jun;23(6):71-73. Unique Identifier : AIDSLINE MED/93288305; Anastasi JK
A.I.D.S. patient--code controversy.: Nursing. 1993 Jun;23(6):81. Unique Identifier : AIDSLINE MED/93288307; Salladay SA
Preventing transmission of bloodborne infections.: Nurs Manage. 1993 Jun;24(6):68-9. Unique Identifier : AIDSLINE MED/93288322; Allen G
Oral surgeons more likely to treat AIDS patients [news]: N Y State Dent J. 1993 May;59(5):59. Unique Identifier : AIDSLINE MED/93288333
Immunoblastic B-cell malignant lymphoma involving the orbit and maxillary sinus in a patient with acquired immune deficiency syndrome.: Ophthalmology. 1993 Jun;100(6):966-70. Unique Identifier : AIDSLINE MED/93288378; Font RL; Laucirica R; Patrinely JR; Department of Ophthalmology, Cullen Eye Institute, Baylor College; of Medicine, Houston, TX 77030.; BACKGROUND: A 44-year-old man was diagnosed with acquired immune deficiency syndrome (AIDS)-related complex in 1986. Four years later, erythema and swelling of the right lower eyelid and face and a palpable mass along the right inferior orbital rim developed. Computed tomographic scans of the orbits disclosed a mass i
Differential effect of HTLV infection and HTLV Tax on interleukin 3 expression.: Oncogene. 1993 Jul;8(7):1905-11. Unique Identifier : AIDSLINE MED/93288405; Wolin M; Kornuc M; Hong C; Shin SK; Lee F; Lau R; Nimer S; Department of Medicine, UCLA School of Medicine 90024-1678.; To characterize the interactions between human T-cell leukemia virus (HTLV) infection and cellular gene expression, we examined the expression of the lymphokine interleukin 3 (IL-3) in the presence and absence of HTLV infection. IL-3, like granulocyte-macrophage colony-stimulating factor (GM-CSF), is produced by activ
Physicians to play key role in halting the new TB threat. Pennsylvania Medical Society Commission on Public Health.: Pa Med. 1993 May;96(5):16-9. Unique Identifier : AIDSLINE MED/93288437; In response to grave concern of Society members about the current and potential impact of the resurgence of tuberculosis on the health and well-being of the people of Pennsylvania, the Commission on Public Health in a position paper outlined Society concerns and suggested ways to halt the new threat of this once perva
HIV hotline for health care providers [news]: Pa Nurse. 1993 May;48(5):11. Unique Identifier : AIDSLINE MED/93288445
Gene therapy--a primer.: Pediatr Ann. 1993 May;22(5):312-21. Unique Identifier : AIDSLINE MED/93288492; Wolff JA; Waisman Center, University of Wisconsin, Madison 53705.
Natural killer cytotoxicity and antibody-dependent cellular cytotoxicity of human immunodeficiency virus-infected cells by leukocytes from human neonates and adults.: Pediatr Res. 1993 May;33(5):469-74. Unique Identifier : AIDSLINE MED/93288519; Jenkins M; Mills J; Kohl S; Department of Pediatrics, San Francisco General Hospital Medical; Center, University of California 94110.; In infants born to mothers infected with the human immunodeficiency virus (HIV), antibody-dependent cellular cytotoxicity (ADCC) or natural killer cytotoxicity (NKC) may either eliminate infection or ameliorate its course. We developed and standardized an assay for cytotoxicity of HIV-infected cells and studied the ca
[Rochalimaea henselae infection. Febrile pancytopenia and hepatic peliosis in a patient with HIV infection]: Presse Med. 1993 Mar 27;22(11):532-4. Unique Identifier : AIDSLINE MED/93288598; Quint L; Jaccard A; Mainguene C; Roulot D; Geoffray C; Hofman P; Oksenhendler E; Clauvel JP; Service d'Immuno-hematologie, Hopital Saint-Louis, Paris.; A case of Rochalimaea henselae infection in an AIDS patient is reported. The R. henselae infection was revealed by febrile pancytopenia associated with liver and spleen enlargement. The diagnosis was made on the finding at histology of hepatic peliosis lesions. Within these lesions Warthin Starry staining displayed ba
[Atypical malignant melanoma in a HIV-positive patient. A fortuitous association? (letter)]: Presse Med. 1993 Mar 27;22(11):553. Unique Identifier : AIDSLINE MED/93288606; Van Landuyt H; Drobacheff C; Bertrand MA; Laurent R
[Cortical blindness disclosing progressive multifocal leukoencephalitis in AIDS (letter)]: Presse Med. 1993 Mar 27;22(11):554. Unique Identifier : AIDSLINE MED/93288609; Lafeuillade A; Pellegrino P; Benderitter T; Quilichini R
[Value of acetate medroxyprogesterone in the treatment of cachexia in AIDS (letter)]: Presse Med. 1993 Apr 3;22(12):597. Unique Identifier : AIDSLINE MED/93288620; Saint-Marc T; Livrozet JM; Fournier F; Rambeaud B; Touraine JL
[Echocardiographic abnormalities in the stage IV of HIV infection]: Presse Med. 1993 Apr 24;22(15):712-6. Unique Identifier : AIDSLINE MED/93288649; Gouello JP; Chennebault JM; Loison J; Bouachour G; Tirot P; Achard J; Service des Maladies infectieuses et Reanimation medicale,; CHRU, Angers.; Fifty patients in stage IV of HIV infection (including 41 AIDS patients) were prospectively studied by echocardiography. Thirteen of them showed abnormalities: 4 had pericardial effusion, 1 endocarditis, 7 myocardial disorders and 1 primary pulmonary arterial hypertension. Pericardial effusion, also present in patient
Incarceration history as a risk factor for HIV infection among Puerto Rican injection drug users.: P R Health Sci J. 1993 Apr;12(1):13-7. Unique Identifier : AIDSLINE MED/93288791; Robles RR; Marrero CA; Freeman DH; Colon HM; Matos TD; Sahai H; Puerto Rico Department of Anti Addiction Services/Center for; Evaluation and Sociomedical Research, School of Public Health,; University of Puerto Rico, San Juan.; This study assesses factors associated with incarceration history and HIV seropositivity among 1,700 out-of-treatment drug injectors recruited in Puerto Rico between 1989-1990 from health care centers, emergency rooms, copping areas, shooting galleries, bars, billiard rooms and
Human immunodeficiency virus infection and risk behaviors among injection drug users in four Puerto Rican communities.: P R Health Sci J. 1993 Apr;12(1):19-25. Unique Identifier : AIDSLINE MED/93288792; Reyes JC; Robles RR; Colon HM; Matos TD; Sahai H; Freeman DH; Dept. of Anti Addiction Services, Commonwealth of Puerto Rico,; San Juan.; This study compares the prevalence of human immunodeficiency virus (HIV) infection and HIV risk behaviors among 1,702 injection drug users (IDUs) recruited within four catchment areas in metropolitan San Juan (79.9% male and 20.1% female). To assess the impact of different antecedent variables on intercommunity risk d
Effects of a HIV risk reduction education program among injection drug users in Puerto Rico.: P R Health Sci J. 1993 Apr;12(1):27-34. Unique Identifier : AIDSLINE MED/93288793; Colon HM; Robles RR; Freeman D; Matos T; Research Institute, Puerto Rico Department of Anti Addiction; Services, Rio Piedras 00928-1414.; This report examines the extent to which an educational component enhanced the efficacy of a community outreach program in reducing HIV transmission behaviors among injecting drug users (IDUs). The experimental enhancement comprised three group educational sessions where detailed information on HIV risk and protective
[Brief history of AIDS in non-human primates and its contribution to the study of acquired immunodeficiency syndrome]: P R Health Sci J. 1993 Apr;12(1):47-54. Unique Identifier : AIDSLINE MED/93288797; Malaga CA; Kraiselburd E; Lavergne JA; Del Llano AM; Amieiro JP; Centro de Recursos Animales, Universidad de Puerto Rico, San Juan; 00936-5067.; Infection of the rhesus monkey (Macaca mulatta) with retroviruses originating from African non human primates (SIV) induces in this species an acquired immunodeficiency syndrome (SAIDS) closely resembling AIDS in humans. Analogies between the SIV-rhesus system and AIDS in humans are described in this work, analyzing t
Drugs and AIDS [editorial]: P R Health Sci J. 1993 Apr;12(1):5. Unique Identifier : AIDSLINE MED/93288798; Robles RR
[Guidelines for the management of women with HIV infection]: P R Health Sci J. 1993 Apr;12(1):55-61. Unique Identifier : AIDSLINE MED/93288799; Zorrilla CD; Romaguera J; Diaz C; Departamento de Obstetricia y Ginecologia, Escuela de Medicina,; Universidad de Puerto Rico.; During the second decade of AIDS the spread of this disease has encompassed most areas of the world. In Puerto Rico the epidemic has been different than in the mainland USA. Our initial cases were mostly associated to intravenous drug use and subsequently heterosexual transmiss
HIV risk behaviors and HIV seropositivity among young injection drug users.: P R Health Sci J. 1993 Apr;12(1):7-12. Unique Identifier : AIDSLINE MED/93288801; Marrero Rodriguez CA; Robles RR; Colon HM; Freeman DH; Matos TD; Reyes JC; Research Institute, Puerto Rico Department of Anti-Addiction; Services, Hato Rey 00928-1414.; Although injection drug use (IDU) is the major risk category for HIV infection in Puerto Rico and injection drug users start their drug injection careers very young, there is little information related to drug injection patterns of young IDUs. In this paper we report on factors
Polio vaccines and the origin of AIDS [letter] [see comments]: Res Virol. 1993 Mar-Apr;144(2):175-7. Unique Identifier : AIDSLINE MED/93289033; Elswood BF; Stricker RB
Use of backcalculation for estimation of the probability of progression from HIV infection to AIDS.: Stat Med. 1993 Apr 15;12(7):617-31. Unique Identifier : AIDSLINE MED/93289185; Marion SA; Schechter MT; Department of Health Care and Epidemiology, Faculty of Medicine,; University of British Columbia, Vancouver, Canada.; Backcalculation has been used to estimate the rate of past HIV infection and to predict future AIDS incidence. In this study we examine another use: estimating the probability of progression from HIV infection to AIDS as a function of time from infection. Given observed AIDS incidence data, the technique of backcalcul
[Tuberculosis, a pathology that has currently returned]: Rev Infirm. 1993 Mar;43(5):46-8. Unique Identifier : AIDSLINE MED/93289227; Harlay A
[Weight loss, a major complication of AIDS]: Rev Infirm. 1993 Mar;43(6):20-2. Unique Identifier : AIDSLINE MED/93289234; Burrus O
[The role of the general practitioner in pathology due to AIDS]: Rev Infirm. 1993 Mar;43(6):23-5. Unique Identifier : AIDSLINE MED/93289235; Thomas M; Gauthier N; Bechu P; Chevalier S; Jeantils V
Occupational blood exposure among health care workers: I. Frequency and reporting.: Scand J Infect Dis. 1993;25(2):193-8. Unique Identifier : AIDSLINE MED/93289263; Nelsing S; Nielsen TL; Nielsen JO; Department of Infectious Diseases, University of Copenhagen,; Hvidovre Hospital, Denmark.; The frequency and reporting rate concerning occupational blood exposure were investigated among former and currently employed medical staff at a Department of Infectious Diseases (DID) having a high prevalence of HIV-positive patients. Subjects were asked to complete an anonymous questionnaire describing occupational
Occupational blood exposure among health care workers: II. Exposure mechanisms and universal precautions.: Scand J Infect Dis. 1993;25(2):199-205. Unique Identifier : AIDSLINE MED/93289264; Nelsing S; Nielsen TL; Nielsen JO; Department of Infectious Diseases, Hvidovre Hospital, University; of Copenhagen, Denmark.; We investigated mechanisms of mucocutaneous exposure (MCE) and percutaneous exposure (PCE) to blood, and compliance with protective barriers among all former and presently employed medical staff at a Danish Department of Infectious Diseases. All subjects were asked to complete an anonymous questionnaire. 135 out of 16
DNA amplification on cerebrospinal fluid for diagnosis of cerebral toxoplasmosis among HIV-positive patients with signs or symptoms of neurological disease.: Scand J Infect Dis. 1993;25(2):227-37. Unique Identifier : AIDSLINE MED/93289268; Ostergaard L; Nielsen AK; Black FT; Department of Infectious Diseases, Marselisborg Hospital, Aarhus,; Denmark.; Reactivation of Toxoplasma gondii can lead to a life-threatening intracerebral infection in immunocompromised HIV-positive patients. Due to the current diagnostic limitations for establishing an exact diagnosis of cerebral toxoplasmosis, a nested PCR system was developed for direct detection of T. gondii in cerebrospi
[How well do condoms protect against HIV infection?]: Schweiz Med Wochenschr. 1993 May 15;123(19):987-96. Unique Identifier : AIDSLINE MED/93289282; Heusser R; Bauer G; Tschopp A; Luthy R; Somaini B; Gutzwiller F; Institut fur Sozial-und Praventivmedizin, Universitat Zurich.; A review of the literature shows that condoms offer good protection against HIV infection and other sexually transmitted diseases. A series of in vitro experiments demonstrate that quality condoms made of latex are impermeable to HIV. In addition, more than 30 in vivo studies confirm that condoms are highly effective
[AIDS and business: who discovered it? (news)]: Schweiz Monatsschr Zahnmed. 1993;103(5):649. Unique Identifier : AIDSLINE MED/93289327
[The setting up of a Blood and AIDS work group (news)]: Schweiz Monatsschr Zahnmed. 1993;103(5):653. Unique Identifier : AIDSLINE MED/93289330
[The HIV test in Switzerland 1992: incidence, pertinence, impact and quality (news)]: Schweiz Monatsschr Zahnmed. 1993;103(5):675. Unique Identifier : AIDSLINE MED/93289332
HIV and AIDS [letter]: Science. 1993 Jun 18;260(5115):1705-6. Unique Identifier : AIDSLINE MED/93289335; Duesberg P
HIV and AIDS [letter]: Science. 1993 Jun 18;260(5115):1707-8. Unique Identifier : AIDSLINE MED/93289337; Laman JD
Natural selection at work on the surface of virus-infected cells.: Science. 1993 Jun 18;260(5115):1771-2. Unique Identifier : AIDSLINE MED/93289353; McMichael A; Institute of Molecular Medicine, John Radcliffe Hospital,; Headington, Oxford, United Kingdom.
[Geographic inequalities in HIV infection and AIDS in sub-saharan Africa]: Soc Sci Med. 1993 May;36(10):1247-56. Unique Identifier : AIDSLINE MED/93289381; Amat-Roze JM; The geography of HIV infection in Africa (which is the continent with the highest incidence rates) has varied features at each scale. The transmission is oriented preferentially according to axes and poles where the virus--because of local environmental factors--found favorable conditions to dissemination and spread.
Social relationships of men at risk for AIDS.: Soc Sci Med. 1993 May;36(9):1161-7. Unique Identifier : AIDSLINE MED/93289417; O'Brien K; Wortman CB; Kessler RC; Joseph JG; Department of Psychology, Portland State University, OR 97207.; Survey data collected in 1984-85 from a community sample of 637 gay and bisexual men were used to determine the features of social relationships that were most conductive to changes in both psychological health and AIDS-related sexual risk behavior. Multiple regression analyses showed that both the perceived availabil
Miliary pulmonary cryptococcosis in a patient with the acquired immunodeficiency syndrome.: Thorax. 1993 Apr;48(4):402-3. Unique Identifier : AIDSLINE MED/93289530; Douketis JD; Kesten S; Toronto Hospital, Ontario, Canada.; A 33 year old man with AIDS presented with fever, dyspnoea, cough and a miliary pattern on the chest radiograph. Cryptococcus neoformans infection was diagnosed from bronchoalveolar lavage bronchoscopy. This case supports the principle that, in patients with AIDS, pulmonary infections can exhibit variable radiographic
Occupational risk to surgeons of unrecognized HIV infection in a low-prevalence area.: World J Surg. 1993 Mar-Apr;17(2):232-5; discussion 236. Unique Identifier : AIDSLINE MED/93289765; Evrard S; Meyer P; van Haaften K; Christmann D; Marescaux J; Department of Surgery A, Hopitaux Universitaires de Strasbourg,; France.; Data are available on the occupational risk to surgeons of the human immunodeficiency virus (HIV) for areas of high HIV prevalence but not for low-risk areas and particularly for unrecognized HIV infection. The 40-year cumulative occupational risk to surgeons caring for patients with unknown HIV serologies in a low-pr
New AIDS definition increases reported cases; physicians asked to review records.: Wis Med J. 1993 Apr;92(4):198. Unique Identifier : AIDSLINE MED/93289782
Contraception and sexually transmitted diseases: interactions and opportunities.: Am J Obstet Gynecol. 1993 Jun;168(6 Pt 2):2033-41. Unique Identifier : AIDSLINE MED/93289931; McGregor JA; Hammill HA; Department of Obstetrics and Gynecology, University of Colorado; Health Sciences Center, Denver 80262.; Today safe sex means protection from both unintended pregnancy and sexually transmitted disease and human immunodeficiency virus. These parallel complications of sexual activity have serious biologic and clinical sequelae that should be considered at the time of contraceptive selection. In addition, there is ongoing d
Study shows that many nurses fear contracting AIDS.: Am Nurse. 1993 Jun;25(6):13. Unique Identifier : AIDSLINE MED/93290028
Chronic diarrhea and malabsorption associated with enteropathogenic bacterial infection in a patient with AIDS.: Ann Intern Med. 1993 Jul 15;119(2):127-8. Unique Identifier : AIDSLINE MED/93290059; Kotler DP; Orenstein JM; St. Luke's-Roosevelt Hospital Center, College of Physicians and; Surgeons, Columbia University, New York, New York.
Quinolinic acid and inflammation.: Ann N Y Acad Sci. 1993 May 28;679:211-6. Unique Identifier : AIDSLINE MED/93290109; Heyes MP; Section of Analytical Biochemistry, Laboratory of Clinical; Science, NIH, Bethesda, Maryland 20892.
[Chronic daily oral low-dose etoposide therapy for an aged patient with aggressive lymphoma: a successful case report]: Gan To Kagaku Ryoho. 1993 Jun;20(8):1079-82. Unique Identifier : AIDSLINE MED/93290378; Sakoda H; Yoshida H; Usami M; Fushimi H; Komaki N; Kameyama M; Fukuhara S; Ohkuma M; Dept. of Internal Medicine, Sumitomo Hospital.; A 72-year-old female from Fukuoka Prefecture was admitted to our hospital complaining of puffy face and general malaise in April, 1992. Physical examinations revealed generalized lymphadenopathy and hepatosplenomegaly complicated with superior vena cava syndrome. A histological diagnosis of diffuse large cell-type mal
Attitude towards serological tests for infection during pregnancy.: Arch Gynecol Obstet. 1993;252(4):161-7. Unique Identifier : AIDSLINE MED/93290386; Donders GG; Desmyter J; Goubau P; van Assche FA; Department of Obstetrics and Gynecology, Katholieke Universiteit,; Leuven, Belgium.; In anticipation of systematic prenatal screening at the antenatal clinic of Gasthuisberg University Hospital, Leuven, Belgium , the attitude of 500 successive pregnant women towards testing for rubella, toxoplasmosis, hepatitis B virus, HIV and syphilis was studied by means of writ
HIV testing of great value to the ESRD patient [letter]: ANNA J. 1993 Apr;20(2):114. Unique Identifier : AIDSLINE MED/93290411; Collins D
The risk of occupational human immunodeficiency virus infection in health care workers. Italian Multicenter Study. The Italian Study Group on Occupational Risk of HIV infection.: Arch Intern Med. 1993 Jun 28;153(12):1451-8. Unique Identifier : AIDSLINE MED/93290485; Ippolito G; Puro V; De Carli G; AIDS Unit RM10, L. Spallanzani Hospital, Rome, Italy.; BACKGROUND: More than 50 cases of occupationally acquired human immunodeficiency virus (HIV) infection in health care workers (HCWs) have been reported worldwide. Determinants of injuries and of infection are important to investigate to design effective prevention programs. METHODS: In
Unrecognized coccidioidomycosis complicating Pneumocystis carinii pneumonia in patients infected with the human immunodeficiency virus and treated with corticosteroids. A report of two cases [see comments]: Arch Intern Med. 1993 Jun 28;153(12):1496-8. Unique Identifier : AIDSLINE MED/93290490; Mahaffey KW; Hippenmeyer CL; Mandel R; Ampel NM; Department of Internal Medicine, University of Arizona Health; Sciences Center, Tucson.; Coccidioidomycosis is becoming increasingly recognized as an opportunistic infection among patients infected with the human immunodeficiency virus. We treated two cases of concomitant coccidioidomycosis and Pneumocystis carinii pneumonia. In each case, the diagnosis
Straight to the Point. ANF HIV/AIDS video in Berlin festival [news]: Aust Nurses J. 1993 Mar;22(8):28. Unique Identifier : AIDSLINE MED/93290570
HIV/AIDS: Medicare is the key to care.: Aust Nurses J. 1993 Mar;22(8):8-9. Unique Identifier : AIDSLINE MED/93290571; Ballard J
Immune stimulation by an antisense oligomer complementary to the rev gene of HIV-1.: Biochem Pharmacol. 1993 May 25;45(10):2037-43. Unique Identifier : AIDSLINE MED/93290693; Branda RF; Moore AL; Mathews L; McCormack JJ; Zon G; Department of Medicine, University of Vermont, Burlington 05405.; Mice developed massive splenomegaly and polyclonal hypergammaglobulinemia within 2 days after intravenous injection of a phosphorothioate oligomer that is antisense to a portion of the rev region of the HIV-1 genome. Histologic examination of spleens from injected animals showed marked expansion of a uniform-appearing
Detection of antibodies to the HIV-1 p25/24 and gp120 proteins by sphere-linked immunodiagnostic assay (SLIDA).: Biotechniques. 1993 May;14(5):774-6, 778-80. Unique Identifier : AIDSLINE MED/93290876; Das P; Hari V; Department of Biological Sciences, Wayne State University,; Detroit, MI 48202.; In this paper, we have used the technique known as sphere-linked immunodiagnostic assay (SLIDA) for the detection of antibodies to HIV-1 p25/24 and gp120 proteins. In this technique, the p25/24 and gp120 proteins were covalently bonded to 0.5 micron carboxylated microspheres. They were then exposed to serial dilutions
Antioxidants inhibit stimulation of HIV transcription.: AIDS Res Hum Retroviruses. 1993 Apr;9(4):299-306. Unique Identifier : AIDSLINE MED/93290923; Staal FJ; Roederer M; Raju PA; Anderson MT; Ela SW; Herzenberg LA; Herzenberg LA; Department of Genetics, Stanford University School of Medicine,; California 94305.; In studies presented here, we demonstrate that antioxidants regulate NF-kappa B activation and signal transduction pathways leading to HIV expression. We show (1) that N-acetyl-L-cysteine (NAC), an antioxidant and an efficient glutathione (GSH) precursor, inhibits NF-kappa B activation and HIV expression under conditi
Simultaneous amplification of multiple HIV-1 DNA sequences from clinical specimens by using nested-primer polymerase chain reaction.: AIDS Res Hum Retroviruses. 1993 Apr;9(4):315-20. Unique Identifier : AIDSLINE MED/93290925; Zazzi M; Romano L; Brasini A; Valensin PE; Department of Molecular Biology, University of Siena, Italy.; A sensitive and specific polymerase chain reaction (PCR) protocol with nested primers was developed for simultaneous amplification of three independent human immunodeficiency virus type 1 (HIV-1) DNA sequences from clinical specimens. DNA samples were first amplified with gag, pol, and env outer primer pairs and then
Cotransfection of HIV-1 molecular clones with restricted cell tropism may yield progeny virus with altered phenotype.: AIDS Res Hum Retroviruses. 1993 Apr;9(4):321-9. Unique Identifier : AIDSLINE MED/93290926; Tan W; Fredriksson R; Bjorndal A; Balfe P; Fenyo EM; Department of Virology, School of Medicine, Karolinska Institute,; Stockholm, Sweden.; Seven infectious molecular clones were obtained from a human immunodeficiency virus type 1 isolate with rapid/high replicative capacity. Biological characterization of progeny viruses obtained after transfection of clones into peripheral blood mononuclear cells showed that six clones yielded virus with restricted cell
Human immunodeficiency virus type 2 multiply spliced transcripts.: AIDS Res Hum Retroviruses. 1993 Apr;9(4):331-5. Unique Identifier : AIDSLINE MED/93290927; Chatterjee P; Garzino-Demo A; Swinney P; Arya SK; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.; Viral transcripts, particularly those of the regulatory genes (e.g., rev) in lymphocytic cells chronically infected with human immunodeficiency virus type 2, consist of two types, differing in the structure of the leader sequence derived from the 5 long terminal repeat (LTR). Some transcripts undergo a specific splic
Comparative analysis of HTLV-I promoter activities reveals no disease-linked pattern of expression.: AIDS Res Hum Retroviruses. 1993 Apr;9(4):337-41. Unique Identifier : AIDSLINE MED/93290928; Gonzalez-Dunia D; Komurian-Pradel F; Chirinian-Syan S; De The G; Brahic M; Ozden S; Departement des Retrovirus, UA Centre National de Recherche; Scientifique (CNRS) 1157, Institut Pasteur, Paris, France.; To investigate the possibility of an association between the type of pathology caused by HTLV-I and the activity of its promoter, we compared the levels of transcription obtained with six LTRs isolated from patients with two different HTLV-I-related diseases: ATL and TSP/HAM. The patients came from different geographi
Human endogenous retroviral element K10 (HERV-K10) encodes a full-length gag homologous 73-kDa protein and a functional protease.: AIDS Res Hum Retroviruses. 1993 Apr;9(4):343-50. Unique Identifier : AIDSLINE MED/93290929; Mueller-Lantzsch N; Sauter M; Weiskircher A; Kramer K; Best B; Buck M; Grasser F; Abteilung Virologie, Universitatskliniken des Saarlandes,; Homburg, Germany.; The gag-homologous region of the human endogenous retrovirus K10 (HERV-K10) was amplified by PCR from human genomic DNA and was analyzed by DNA cloning, sequencing, and expression of open reading frames in the prokaryotic pATH expression system. The analysis of genomic DNA of three donors provided evidence that HERV-K
Phylogenetic and serological characterization of two Ugandan HIV-1 isolates.: AIDS Res Hum Retroviruses. 1993 Apr;9(4):351-6. Unique Identifier : AIDSLINE GENBANK/M98504; Atkin A; Pestano G; Serwadda D; Prince AM; Pascual D; Sewankambo N; Boto WM; Department of Biology, City College of City University of New; York, New York 10031.; HIV-1 isolates Ug06 and Ug23 were established in culture from peripheral blood mononuclear cells (PBMCs) of Ugandan subjects. The isolates were studied for phylogenetic and serological relationships with each other and with the laboratory strains, HTLV-IIIB and HIV-1MN. The results suggest that the Ugandan isolates ar
Sequence analysis of the gp120 region of the env gene of Ugandan human immunodeficiency proviruses from a single individual.: AIDS Res Hum Retroviruses. 1993 Apr;9(4):357-63. Unique Identifier : AIDSLINE MED/93290931; Bruce C; Clegg C; Featherstone A; Smith J; Oram J; Centre for Applied Microbiology and Research, Public Health; Laboratory Service, Porton Down, Salisbury, England.; DNA sequences encoding the surface glycoprotein gp120 of the human immunodeficiency virus type 1 (HIV-1) were amplified by the polymerase chain reaction (PCR) from peripheral blood mononuclear cells obtained from a Ugandan AIDS patient. The PCR-amplified DNA was cloned into a phagemid vector and nine clones sequenced.
Clarithromycin effectively treats infection in AIDS patients [news]: Oncology (Huntingt). 1993 May;7(5):57. Unique Identifier : AIDSLINE MED/93290979
Cost of HIV care to reach $15 billion by 1995 [news]: Oncology (Huntingt). 1993 May;7(5):90. Unique Identifier : AIDSLINE MED/93290986
HIV/AIDS: evaluating the risks [news]: Nurs Stand. 1993 Apr 28-May 4;7(32):18. Unique Identifier : AIDSLINE MED/93291064; Alderman C
Health care worker infected with HIV [news]: Nurs Stand. 1993 Apr 28-May 4;7(32):6. Unique Identifier : AIDSLINE MED/93291079
Publicity over HIV-positive health workers [news]: Nurs Stand. 1993 May 26-Jun 1;7(36):11. Unique Identifier : AIDSLINE MED/93291080
School nurses need support, training and resources in educating children about HIV and AIDS [news]: Nurs Stand. 1993 May 26-Jun 1;7(36):13. Unique Identifier : AIDSLINE MED/93291081
HIV-positive nurse goes to ground [news]: Nurs Stand. 1993 May 26-Jun 1;7(36):6. Unique Identifier : AIDSLINE MED/93291093
[Production of hepatitis B virus from peripheral blood lymphocytes stimulated with phytohemagglutinin]: Enferm Infecc Microbiol Clin. 1993 Apr;11(4):187-9. Unique Identifier : AIDSLINE MED/93291220; Sarria L; Gallego L; de las Heras B; Basaras M; Cisterna R; Departamento de Microbiologia e Inmunologia, Universidad del; Pais Vasco.; BACKGROUND: It was studied the production of HBV from lymphocytes from peripheral blood induced with a mitogen agent as phytohemagglutinin (PHA), in patients infected by HIV. METHODS: The methodology developed included the culture of peripheral blood mononuclear cells and its induction to proliferate with PHA, in orde
[Subcutaneous venous reservoirs: comparative study of their efficacy in patients with AIDS versus oncology and hematology patients]: Enferm Infecc Microbiol Clin. 1993 Apr;11(4):190-4. Unique Identifier : AIDSLINE MED/93291221; Moral A; Targarona EM; Mallolas J; Martinez J; Pros I; Valverde M; Palombo H; Trias M; Servicio de Cirugia, Hospital Clinic i Provincial, Barcelona.; BACKGROUND: Chronic venous access may constitute a serious problem in some patients and the subcutaneous venous reservoirs have demonstrated to be a useful alternative. AIDS patients require intense pharmacologic treatment, thus the use of subcutaneous venous reservoirs may be specially useful. However, the prevalence
[Pulmonary toxoplasmosis. Study of 4 cases and review of the literature]: Enferm Infecc Microbiol Clin. 1993 Apr;11(4):195-8. Unique Identifier : AIDSLINE MED/93291222; Asensi V; Carton JA; Maradona JA; de Ona M; Melon S; Asensi JM; Martinez A; Tuya MJ; Arribas JM; Unidad de Enfermedades Infecciosas, Hospital Central de Asturias,; Universidad de Oviedo.; BACKGROUND: Description of four cases of pulmonary toxoplasmosis and review of the literature. METHODS: A retrospective analysis (October 1990-December 1992) was carried out of the patients with samples of tracheal aspirate, bronchoalveolar lavage (BAL) and lung biopsy positive for T. gondii by immunofluorescence with
AIDS-ology: an interventional specialty [see comments]: Clin Infect Dis. 1993 Apr;16(4):459-62. Unique Identifier : AIDSLINE MED/93291328; Verghese A; Department of Internal Medicine, Texas Tech University Health; Sciences Center, El Paso.; The AIDS Commentaries have focused primarily upon the clinical aspects of infection due to the human immunodeficiency virus as documented in academic centers based in large metropolitan areas. Clinicians outside the epicenters of the epidemic face a different set of problems. Dr. Verghese has previously shared his exp
Epidemiology of extrapulmonary tuberculosis among persons with AIDS in the United States.: Clin Infect Dis. 1993 Apr;16(4):513-8. Unique Identifier : AIDSLINE MED/93291338; Slutsker L; Castro KG; Ward JW; Dooley SW Jr; Surveillance Branch, Centers for Disease Control, Atlanta,; Georgia 30333.; AIDS surveillance data reported to the Centers for Disease Control from January 1981 through December 1991 were analyzed in a study characterizing persons with human immunodeficiency virus (HIV) infection and extrapulmonary tuberculosis (EPTB) in the United States . Among 206,392 person
Predictive value of bronchoalveolar lavage in excluding a diagnosis of Pneumocystis carinii pneumonia during prophylaxis with aerosolized pentamidine.: Clin Infect Dis. 1993 Apr;16(4):519-22. Unique Identifier : AIDSLINE MED/93291339; Teuscher AU; Opravil M; Theiler R; Speich R; Kuster H; Siegenthaler W; Russi EW; Luthy R; Department of Medicine, University Hospital, Zurich,; Switzerland.; We assessed the negative predictive value of bronchoalveolar lavage (BAL) for Pneumocystis carinii pneumonia (PCP) during prophylaxis with aerosolized pentamidine. On the basis of the assumption that undiagnosed and untreated PCP would progress and become clinically apparent, for 3 months we prospectively followed 34
A cutaneous lesion in a patient with AIDS: an unusual presentation of infection due to Mycobacterium avium complex.: Clin Infect Dis. 1993 Apr;16(4):555-7. Unique Identifier : AIDSLINE MED/93291346; Clark JA; Margolis DM; Division of Infectious Diseases, University of Massachusetts; Medical Center, Worcester.; A patient with AIDS developed a purplish, necrotic skin lesion followed by fevers, constitutional symptoms, and watery diarrhea. Stains of samples from the skin lesion and of stool and bone marrow revealed acid-fast bacilli, and Mycobacterium avium was isolated from cultures of these specimens and blood. With the init
[Mycobacteriosis from Mycobacterium szulgai in a patient with human immunodeficiency virus infection]: An Med Interna. 1993 Apr;10(4):182-4. Unique Identifier : AIDSLINE MED/93291370; Roig P; Nieto A; Navarro V; Bernacer B; Borras R; Servicio Medicina Interna, Hospital General Universitario,; Valencia.; We present a case of renal and, probably, bone mycobacteriosis by M. szulgai in a patient infected by the human immunodeficiency virus (HIV). M. szulgai is an atypical skotochromogen mycobacterium rarely described in the literature. Clinically, it is characterized by the predominance of pulmonary manifestations undist
Statistical models for prevalent cohort data [see comments]: Biometrics. 1993 Mar;49(1):1-11. Unique Identifier : AIDSLINE MED/93291381; Wang MC; Brookmeyer R; Jewell NP; Department of Biostatistics, Johns Hopkins University, Baltimore,; Maryland 21205.; In prospective cohort studies individuals are sometimes recruited according to a certain cross-sectional sampling criterion. A prevalent cohort is defined as a group of individuals who have a certain disease at enrollment into the study. Statistical models for the analysis of prevalent cohort data are considered when
Analyzing doubly censored data with covariates, with application to AIDS.: Biometrics. 1993 Mar;49(1):13-22. Unique Identifier : AIDSLINE MED/93291384; Kim MY; De Gruttola VG; Lagakos SW; Department of Environmental Medicine, New York University Medical; Center, New York 10010.; This paper proposes a method for incorporating covariate information in the analysis of survival data when both the time of the originating event and the failure event can be right- or interval-censored. This method generalizes the one-sample estimation results of De Gruttola and Lagakos (1989, Biometrics 45, 1-11) by
School-based health care: an inner-city experience.: R I Med. 1993 Apr;76(4):185-9. Unique Identifier : AIDSLINE MED/93291481; Vaz RM; Greene A; Griffin J; Providence Ambulatory Health Care Foundation, Inc., RI 02906.
[HIV infection in Norway]: Sykepl Fag. 1993 Jun 15;81(3):12-5. Unique Identifier : AIDSLINE MED/93291899; Nilsen O
[HIV and AIDS. An encounter with ourselves]: Sykepl Fag. 1993 Jun 15;81(3):16-9. Unique Identifier : AIDSLINE MED/93291900; Leines O
[HIV and AIDS--here and now (editorial)]: Sykepl Fag. 1993 Jun 15;81(3):2. Unique Identifier : AIDSLINE MED/93291901; Svaboe HM
[HIV and AIDS--an oasis for the HIV-positive]: Sykepl Fag. 1993 Jun 15;81(3):20-2. Unique Identifier : AIDSLINE MED/93291902; Wage J
[HIV-positivity in the outer reaches of Norway]: Sykepl Fag. 1993 Jun 15;81(3):22-6. Unique Identifier : AIDSLINE MED/93291903; Midtgard G
[HIV and AIDS in the world today]: Sykepl Fag. 1993 Jun 15;81(3):27-30. Unique Identifier : AIDSLINE MED/93291904; Hasseltvedt V
[Nursing care of AIDS patients in Ulleval hospital]: Sykepl Fag. 1993 Jun 15;81(3):3-7. Unique Identifier : AIDSLINE MED/93291905; Dalgard R; Nygard H
[HIV and AIDS. LMA (National Association against AIDS) seeks annual TV action]: Sykepl Fag. 1993 Jun 15;81(3):31-2. Unique Identifier : AIDSLINE MED/93291906; Bakke KA
[HIV and AIDS--useful addresses and telephone numbers]: Sykepl Fag. 1993 Jun 15;81(3):33. Unique Identifier : AIDSLINE MED/93291907
[HIV and AIDS. Home care project in Rwanda]: Sykepl Fag. 1993 Jun 15;81(3):34. Unique Identifier : AIDSLINE MED/93291908; Almedal C
[HIV and AIDS around the world]: Sykepl Fag. 1993 Jun 15;81(3):35-6. Unique Identifier : AIDSLINE MED/93291909
[HIV and AIDS--living with dignity]: Sykepl Fag. 1993 Jun 15;81(3):8-11. Unique Identifier : AIDSLINE MED/93291922; Hovland A
HIV insurance coverage.: J Can Dent Assoc. 1993 Jun;59(6):515. Unique Identifier : AIDSLINE MED/93291978; Moran R
Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B.: Cell. 1993 Jun 18;73(6):1067-78. Unique Identifier : AIDSLINE MED/93292069; Luban J; Bossolt KL; Franke EK; Kalpana GV; Goff SP; Department of Medicine, Columbia University, College of; Physicians and Surgeons, New York, New York 10032.; Retroviral Gag protein is capable of directing the assembly of virion particles independent of other retroviral elements and plays an important role early in the infection of a cell. Using the GAL4 two hybrid system, we screened a cDNA expression library and identified two host proteins, cyclophillins (CyPs) A and B,
Acquired immunodeficiency syndrome: case reporting at a university hospital.: Cleve Clin J Med. 1993 May-Jun;60(3):202-6. Unique Identifier : AIDSLINE MED/93292135; Picken A; Plona R; Parker P; Carey JT; Lederman MM; Division of Infectious Diseases, Case Western Reserve University; School of Medicine, Cleveland, OH.; BACKGROUND: Planning and allocating resources for care of patients with acquired immunodeficiency syndrome (AIDS) requires accurate assessment of disease incidence. OBJECTIVE: To assess the accuracy and completeness of AIDS case reporting at our institution, we reviewed all inpatient and outpatient records of patients
Mucosal macrophage subsets of the gut in HIV: decrease in antigen-presenting cell phenotype.: Clin Exp Immunol. 1993 Jun;92(3):442-7. Unique Identifier : AIDSLINE MED/93292187; Lim SG; Condez A; Poulter LW; University Department of Medicine, Royal Free Hospital School of; Medicine, London, UK.; The effect of HIV infection on intestinal lamina propria macrophage subsets was investigated in 41 patients at various stages of HIV infection (asymptomatic HIV infection, n = 17; AIDS, n = 24). Duodenal biopsies taken from HIV patients at endoscopy were snap frozen and cryostat sections cut for immunohistochemical st
Symptomatic sulfadiazine crystalluria in AIDS patients: a report of two cases [see comments]: Clin Nephrol. 1993 May;39(5):254-6. Unique Identifier : AIDSLINE MED/93292222; Hein R; Brunkhorst R; Thon WF; Schedel I; Schmidt RE; Zentrum Innere Medizin und Dermatologie, Medizinische Hochschule; Hannover, Germany.; As the incidence of toxoplasma encephalitis (TE) in AIDS patients increases, sulfadiazine/pyrimethamine combination therapy is broadly administered. Two cases of acute and chronic renal sulfadiazine crystallization with acute renal failure and nephrolithiasis are repor
Human immunodeficiency virus infection in pregnancy.: Baillieres Clin Obstet Gynaecol. 1993 Mar;7(1):45-74. Unique Identifier : AIDSLINE MED/93292270; Kesson A; Sorrell T; Human immunodeficiency virus (HIV) infection in women is an increasing problem. World wide, at least 25% of all infections occur in adolescent or adult women, most of whom are of child-bearing age. The commonest modes of acquisition of HIV infection are sexual contact with an HIV-infected male and sharing needles duri
Disseminated histoplasmosis in a patient with acquired immunodeficiency syndrome (AIDS): a case report.: East Afr Med J. 1993 Jan;70(1):61-2. Unique Identifier : AIDSLINE MED/93292425; Amayo EO; Riyat MS; Okelo GB; Adam AM; Toroitich K; Department of Medicine, College of Health Sciences, University of; Nairobi.; A 27 year old female with AIDS and disseminated histoplasmosis is presented. The clinical features include fever, weight loss, productive cough, splenomegaly and moderate pallor. The initial working diagnosis was pulmonary tuberculosis. The diagnosis of disseminated histoplasmosis was made terminally from bone marrow
Pregnancy outcome and placental weights: their relationship to HIV-1 infection.: East Afr Med J. 1993 Feb;70(2):85-9. Unique Identifier : AIDSLINE MED/93292441; Gichangi PB; Nyongo AO; Temmerman M; Department of Human Pathology, University of Nairobi.; The relationship between placental characteristics, including weight and inflammation, and pregnancy outcome was examined as part of a case control study looking into the impact of maternal HIV-1 infection on pregnancy outcome. Cases defined as low birth weight (
Oligomerization of the Nef protein from human immunodeficiency virus (HIV) type 1.: Eur J Biochem. 1993 Jun 1;214(2):451-7. Unique Identifier : AIDSLINE MED/93292506; Kienzle N; Freund J; Kalbitzer HR; Mueller-Lantzsch N; University of the Saarland, Dept. Virology, Homburg/Saar, FRG.; The nef genes, derived from two different human immunodeficiency-virus-type-1 (HIV-1) strains, were expressed in procaryotic cells (Escherichia coli) and in eucaryotic cells (insect cells infected with nef-containing baculovirus). The oligomerization of recombinant Nef protein was studied by NMR spectroscopy and immun
Isolation of Bordetella bronchiseptica from a patient with AIDS [letter]: Eur J Clin Microbiol Infect Dis. 1993 Apr;12(4):304-6. Unique Identifier : AIDSLINE MED/93292540; Mesnard R; Guiso N; Michelet C; Sire JM; Pouedras P; Donnio PY; Avril JL
Acid secretion in human immunodeficiency virus infection.: Gastroenterology. 1993 Jul;105(1):298-9. Unique Identifier : AIDSLINE MED/93292830; Laine L
[HIV infected patients usually treated as outpatients. H. Jager, Munich, on the management of AIDS patients in general practice]: Fortschr Med. 1993 May 10;111(13):28-9. Unique Identifier : AIDSLINE MED/93293105; Jager H
[Generation of a monoclonal antibody specific to human T cell receptor V beta 22, and analysis of peripheral blood T cell repertoire utilizing this monoclonal antibody]: Fukuoka Igaku Zasshi. 1993 Feb;84(2):58-67. Unique Identifier : AIDSLINE MED/93293115; Okamoto Y; Department of genetics, Kyushu University 69, Fukuoka.; A murine monoclonal antibody, R1-21, against a HLA-DR4 restricted CD4+ T cell line specific to streptococcal cell wall (SCW) Ag was generated. R1-21 reacted with about 50% of the HLA-DR4 restricted CD4+ T cell line. R1-21 distinguished a diversity of TCR because it reacted with a small population of peripheral T lymph
Peripheral T-cell lymphoma: a clinicopathological study of 41 cases and evaluation of the prognostic significance of the updated Kiel classification.: Histopathology. 1993 Apr;22(4):303-10. Unique Identifier : AIDSLINE MED/93293167; Montalban C; Obeso G; Gallego A; Castrillo JM; Bellas C; Rivas C; Department of Internal Medicine, Hospital Ramon y Cajal,; Universidad de Alcala, Spain.; A total of 41 non-cutaneous peripheral T-cell lymphomas were classified following the updated Kiel classification. Of these, 20 cases belonged to the low-grade group (T-cell chronic lymphocytic leukaemia, 3; lymphoepithelioid, 5; angioimmunoblastic, 4; pleomorphic small cell, 8) and 21 to the high grade group (pleomor
The intracellular bacterium Rhodococcus equi requires Mac-1 to bind to mammalian cells.: Infect Immun. 1993 Jul;61(7):2919-29. Unique Identifier : AIDSLINE MED/93293312; Hondalus MK; Diamond MS; Rosenthal LA; Springer TA; Mosser DM; Department of Microbiology and Immunology, Temple University; School of Medicine, Philadelphia, Pennsylvania 19140.; Rhodococcus equi is a facultative intracellular bacterium of macrophages that causes disease in immunocompromised individuals, particularly those with AIDS. In this report, we demonstrate that R. equi binding to mammalian cells requires complement and is mediated primarily by the leukocyte complement receptor, Mac-1.
Infection with Mycobacterium avium induces production of interleukin-10 (IL-10), and administration of anti-IL-10 antibody is associated with enhanced resistance to infection in mice.: Infect Immun. 1993 Jul;61(7):3093-7. Unique Identifier : AIDSLINE MED/93293340; Bermudez LE; Champsi J; Kuzell Institute for Arthritis and Infectious Diseases,; California Pacific Medical Center, San Francisco 94115.; Organisms of the Mycobacterium avium complex are associated with disseminated infection in patients with AIDS. The mechanisms that account for the survival of the intracellular bacteria are unknown. We document here that infection of C57BL/6 black mice with M. avium 101 triggered interleukin-10 (IL-10) production. The
Expression of the target antigen for cytotoxic T lymphocytes on adult T-cell-leukemia cells.: Int J Cancer. 1993 Jun 19;54(4):582-8. Unique Identifier : AIDSLINE MED/93293375; Kannagi M; Matsushita S; Harada S; Department of Biodefence and Medical Virology, Kumamoto; University School of Medicine, Japan.; Adult T-cell-leukemia (ATL) cells were examined for susceptibility to human T-cell-leukemia virus type I (HTLV-I) tax-specific cytotoxic T lymphocytes (CTL) derived from a patient with HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). These CTL efficiently killed HLA-matched leukemia cells of an ATL
[Anaerobic infections in the head and neck area. Current status of knowledge]: HNO. 1993 Apr;41(4):222-9. Unique Identifier : AIDSLINE MED/93293538; Luckhaupt H; Ahrens A; HNO-Klinik, Ruhr-Universitat Bochum.; The classification of anaerobic infections and the most common organisms affecting the head and neck, pathogenesis diagnosis and current therapy are reported. Certain types of infections are particularly important for anaerobic bacteria and include actinomycosis, infectious complications of chronic otitis media or sin
The crystallographic structure of the protease from human immunodeficiency virus type 2 with two synthetic peptidic transition state analog inhibitors.: J Biol Chem. 1993 Jun 25;268(18):13103-9. Unique Identifier : AIDSLINE MED/93293821; Mulichak AM; Hui JO; Tomasselli AG; Heinrikson RL; Curry KA; Tomich CS; Thaisrivongs S; Sawyer TK; Watenpaugh KD; Discovery Research, Upjohn Company, Kalamazoo, Michigan 49007.; The crystal structure of human immunodeficiency virus (HIV) type 2 protease has been determined in complexes with peptidic inhibitors Noa-His-Cha psi [CH(OH)CH(OH)]Val-Ile-Amp (U75875) and Qnc-Asn-Cha psi [CH(OH)CH2]Val-Npt(U92163) (where Noa is naphthyloxyacetyl, Cha is cyclohexylalanine, Amp is 2-aminomethylpyridine
Biochemical and immunological characterization of micellar complexes of the envelope glycoprotein of a simian immunodeficiency virus isolated from an African green monkey.: J Virol Methods. 1993 May;42(2-3):169-80. Unique Identifier : AIDSLINE MED/93293946; Luke W; Polzien F; Scharf JG; Hunsmann G; German Primate Centre, Gottingen.; The external envelope glycoprotein gp130 of a simian immunodeficiency virus isolated from an African green monkey (SIVagmTYO-7) was purified as micellar complexes. The molecular weight of the gp130 micelles was about 700 K. On electron microscopy, the micelles appeared as spherical particles with a diameter of 15 to 2
Primer extension analysis provides a sensitive tool for the identification of PCR-amplified DNA from HIV-1.: J Virol Methods. 1993 May;42(2-3):309-22. Unique Identifier : AIDSLINE GENBANK/K03455; Boni J; Schupbach J; Swiss National Center for Retroviruses, University of Zurich.; Primer extension analysis was evaluated as a means to identify PCR-amplified DNA from HIV-1. Solution hybridization with radioactive labeled oligonucleotides followed by an extension reaction with Klenow fragment of Escherichia coli DNA polymerase I and subsequent separation on denaturing polyacrylamide gels reveals s
Early molecular replication of human immunodeficiency virus type 1 in cultured-blood-derived T helper dendritic cells.: J Clin Invest. 1993 Jun;91(6):2721-6. Unique Identifier : AIDSLINE MED/93294010; Langhoff E; Kalland KH; Haseltine WA; Division of Human Retrovirology, Dana-Farber Cancer Institute,; Boston, Massachusetts 02115.; The rate and efficiency of key steps in the life cycle of the human immunodeficiency virus type 1 was examined in three primary cell types, T cells, monocytes, and T helper dendritic cells using the same quantity of virus involved and same cell number. The results show that viral DNA synthesis proceeds much more rapid
Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brains.: J Clin Invest. 1993 Jun;91(6):2769-75. Unique Identifier : AIDSLINE MED/93294016; Achim CL; Heyes MP; Wiley CA; Department of Pathology, University of California San Diego, La; Jolla 92093-0612.; HIV encephalitis is unusual in that neurologic damage occurs in the absence of significant infection of neuronal or glial cells. Because the predominant infected cell in the brain is the macrophage, it has been proposed that release of viral or immune activation factors from macrophages may mediate neurologic damage.
Burn-out in hospital nurses: a comparison of acquired immunodeficiency syndrome, oncology, general medical, and intensive care unit nurse samples.: J Prof Nurs. 1993 May-Jun;9(3):169-77. Unique Identifier : AIDSLINE MED/93294102; van Servellen G; Leake B; School of Nursing, University of California Los Angeles.; Previous research has shown that job-related stress and burn-out are associated with high levels of demand placed on the worker, especially in situations where influence is low. This study examined burn-out among nurses working on acquired immunodeficiency syndrome (AIDS) special care units (SCUs), oncology SCUs, medi
Peer education in the residential context.: J Am Coll Health. 1993 May;41(6):271-2. Unique Identifier : AIDSLINE MED/93294122; Bauman DW 3d; State University of New York, Stony Brook.; Research on HIV-prevention education with college students has demonstrated that interventions that provide only information do not bring about risk-reducing changes in behavior. Given the chronic nature of HIV infection, as well as data that show that students do not consistently use condoms and practice safer sex, p
Training opinion leaders to promote safer sex.: J Am Coll Health. 1993 May;41(6):273-4. Unique Identifier : AIDSLINE MED/93294123; Grossberg PM; Tillotson TS; Roberts CM; Roach KJ; Brault BA; University Health Service, University of Wisconsin-Madison.; Training opinion leaders in a men s residence hall in a brief program focused on communication and life skills is an effective way to stimulate peer discussions on HIV prevention and risk reduction and appears likely to have positive influences on behavioral change or intention. The program at the University of Wiscon
Sex, truth, and womantalk: what your mother never taught you.: J Am Coll Health. 1993 May;41(6):279-80. Unique Identifier : AIDSLINE MED/93294125; Getty A; Bannan HM; Student Health Center, Florida Atlantic University, Boca Raton.; This article describes a project based on feminist theory and pedagogical techniques that used students as peer facilitators. The program was designed to maintain and enhance health-promoting sexual behaviors among female college students in response to the premise that women s gender socialization limits their abilit
Peer-based HIV risk assessment: a step-by-step guide through the teachable moment.: J Am Coll Health. 1993 May;41(6):297-9. Unique Identifier : AIDSLINE MED/93294129; Fabiano P; Western Washington University, Bellingham.; Peer educators in HIV prevention have influence with other students beyond the narrowly defined traditional activities of workshop presentations of outreach projects. Training HIV prevention peer educators to be prepared for the teachable moments when other students seek their assistance on assessing risk for HIV infe
Construction of an HIV-1 peptide vaccine containing a multideterminant helper peptide linked to a V3 loop peptide 18 inducing strong neutralizing antibody responses in mice of multiple MHC haplotypes after two immunizations.: J Immunol. 1993 Jun 15;150(12):5647-65. Unique Identifier : AIDSLINE MED/93294321; Ahlers JD; Pendleton CD; Dunlop N; Minassian A; Nara PL; Berzofsky JA; Molecular Immunogenetics and Vaccine Research Section, National; Cancer Institute, National Institute of Health, Bethesda, MD; 20892.; Peptide constructs comprised of multideterminant Th peptides from the envelope glycoprotein of HIV previously identified to induce proliferative responses in four different haplotypes of mice and IL-2 responses in 52 to 73% of HIV positive, Ag-responsive patients, were
Parvovirus B19 infection in human immunodeficiency virus type 1-infected persons failing or intolerant to zidovudine therapy [see comments]: J Infect Dis. 1993 Jul;168(1):101-5. Unique Identifier : AIDSLINE MED/93294342; Naides SJ; Howard EJ; Swack NS; True CA; Stapleton JT; Dept. of Internal Medicine, University of Iowa College of; Medicine, Iowa City 52242.; To determine the incidence of B19 infection in patients with AIDS who were being treated with dideoxyinosine, serial sera (n = 28) taken over a 2-year period from 14 individuals were analyzed with respect to anti-B19 serology and the presence of B19 DNA. All 14 individuals were anti-B19 IgM negative. Nine of 14 had B1
Mycobacterium tuberculosis in household contacts of human immunodeficiency virus type 1-seropositive patients with active pulmonary tuberculosis in Kinshasa, Zaire [published erratum appears in J Infect Dis 1993 Sep;168(3):802]: J Infect Dis. 1993 Jul;168(1):106-11. Unique Identifier : AIDSLINE MED/93294343; Klausner JD; Ryder RW; Baende E; Lelo U; Williame JC; Ngamboli K; Perriens JH; Kaboto M; Prignot J; Department of Medicine, New York University Medical Center, New; York.; Rates of infection with Mycobacterium tuberculosis were compared in Kinshasa, Zaire , in 521 household contacts of 74 human immunodeficiency virus type 1 (HIV-1)-seropositive index patients and in 692 household contacts of 95 HIV-1-seronegative [corrected] index patients with sputu
Randomized, placebo-controlled trial of rifampin, ethambutol, and ciprofloxacin for AIDS patients with disseminated Mycobacterium avium complex infection [published erratum appears in J Infect Dis 1993 Sep;168(3):802]: J Infect Dis. 1993 Jul;168(1):112-9. Unique Identifier : AIDSLINE MED/93294344; Jacobson MA; Yajko D; Northfelt D; Charlebois E; Gary D; Brosgart C; Sanders CA; Hadley WK; Department of Medicine, University of California, San Francisco.; Patients with AIDS and disseminated Mycobacterium avium complex (MAC) infection received rifampin (600 mg) plus ethambutol (25 mg/kg) plus ciprofloxacin (750 mg) or matching placebos daily for 8 weeks. Patients were monitored every 2 weeks clinically and by quantitating MAC colony-forming units (cfu) per milliliter of
Further evidence of host species-specific variation in antigens of Pneumocystis carinii using the polymerase chain reaction.: J Infect Dis. 1993 Jul;168(1):191-4. Unique Identifier : AIDSLINE MED/93294356; Gigliotti F; Haidaris PJ; Haidaris CG; Wright TW; Van der Meid KR; Department of Pediatrics, University of Rochester School of; Medicine and Dentistry, New York.; To further elucidate the extent of variation among Pneumocystis carinii obtained from different mammalian hosts, polymerase chain reaction (PCR) analysis of the genes encoding two antigens of P. carinii was done. Using primers based on the ferret P. carinii glycoprotein (gp)A gene and the rat P. carinii 45- to 55-kDa
Mother-to-child transmission of human immunodeficiency virus type 1: correlation with neutralizing antibodies against primary isolates.: J Infect Dis. 1993 Jul;168(1):207-10. Unique Identifier : AIDSLINE MED/93294359; Scarlatti G; Albert J; Rossi P; Hodara V; Biraghi P; Muggiasca L; Fenyo EM; Department of Virology, Karolinska Institute, Stockholm, Sweden.; The aim of this study was to investigate the influence of neutralizing antibodies in mother s serum on the risk of mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1). Sera from 20 HIV-1 infected mothers were analyzed for their ability to neutralize their own virus (autologous neutralization) a
Herpes zoster and human immunodeficiency virus infection: a cohort study of 101 coinfected patients. Groupe d'Epidemiologie clinique du SIDA en aquitaine [letter; comment]: J Infect Dis. 1993 Jul;168(1):245. Unique Identifier : AIDSLINE MED/93294370; Rogues AM; Dupon M; Ladner J; Ragnaud JM; Pellegrin JL; Dabis F
Soluble CD4 levels in human immunodeficiency virus-infected patients [letter]: J Infect Dis. 1993 Jul;168(1):246. Unique Identifier : AIDSLINE MED/93294371; Reddy MM
Pharmacokinetics of liposomal nystatin in patients with human immunodeficiency virus infection [letter]: J Infect Dis. 1993 Jul;168(1):253-4. Unique Identifier : AIDSLINE MED/93294379; Rios A; Rosenblum M; Crofoot G; Lenk RP; Hayman A; Lopez-Berestein G
Gender differences in reported AIDS-indicative diagnoses.: J Infect Dis. 1993 Jul;168(1):61-7. Unique Identifier : AIDSLINE MED/93294389; Fleming PL; Ciesielski CA; Byers RH; Castro KG; Berkelman RL; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, GA 30333.; To compare AIDS-defining conditions in women and men, US adult AIDS cases diagnosed between January 1988 and June 1991 and reported to the Centers for Disease Control and Prevention through June 1992 were examined. For most AIDS-defining conditions, the prevalence was similar for women and men when differences in race
Virologic markers of human immunodeficiency virus type 1 in cerebrospinal fluid. The HIV Neurobehavioral Research Center Group.: J Infect Dis. 1993 Jul;168(1):68-74. Unique Identifier : AIDSLINE MED/93294390; Spector SA; Hsia K; Pratt D; Lathey J; McCutchan JA; Alcaraz JE; Atkinson JH; Gulevich S; Wallace M; Grant I; Department of Pediatrics, University of California, San Diego, La; Jolla 92093.; As part of a longitudinal study, 265 cerebrospinal fluid (CSF) specimens from 204 human immunodeficiency virus type 1 (HIV-1)-seropositive subjects and 43 seronegative controls were evaluated. Of the 204 seropositive persons, 78 (38%) had > or = 1 CSF culture positive for HIV-1; the probability of being culture positi
Increased phagocytosis and generation of reactive oxygen products by neutrophils and monocytes of men with stage 1 human immunodeficiency virus infection.: J Infect Dis. 1993 Jul;168(1):75-83. Unique Identifier : AIDSLINE MED/93294391; Bandres JC; Trial J; Musher DM; Rossen RD; Research Center for AIDS and HIV-Associated Diseases, VA Medical; Center, Houston, TX 77030.; Flow cytometry was used to study phagocytic function and release of reactive oxygen products following phagocytosis by neutrophils (PMNL) and monocytes of heparinized whole blood from stage 1 human immunodeficiency virus type 1 (HIV-1)-infected men. Phagocytic capacity was assessed by measuring uptake of Texas red-lab
Infection of epithelial cell line HEp-2 with human immunodeficiency virus type 1 is CD4 dependent.: J Med Virol. 1993 May;40(1):39-43. Unique Identifier : AIDSLINE MED/93294550; Nottet HS; Janse I; de Graaf L; Bakker LJ; Visser MR; Verhoef J; Eijkman-Winkler Laboratory for Medical Microbiology, University; of Utrecht, The Netherlands.; HEp-2 cells, human epithelial cells derived from a larynx carcinoma, were found to be highly susceptible to infection with HIV-1 stain IIIb and MN, but not to infection with the monotropic strain IIIBa-L or the clinical isolate HIV-1AT. HEp-2 cells infected with HIV-1 IIIb continuously secreted high levels of p24 anti
Should there be mandatory human immunodeficiency virus testing for pregnant women? [editorial]: J Perinatol. 1993 Mar-Apr;13(2):91-2. Unique Identifier : AIDSLINE MED/93294649; Sherwen LN
Rural HIV infection: the window of opportunity for action is still wide open.: J Gen Intern Med. 1993 Apr;8(4):210-2. Unique Identifier : AIDSLINE MED/93294666; Helms CM; Department of Internal Medicine, University of Iowa College of; Medicine, Iowa City.
Home infusion of intravenous immune globulin in human immunodeficiency virus--infected children [letter; comment]: J Intraven Nurs. 1993 May-Jun;16(3):195. Unique Identifier : AIDSLINE MED/93294674; Poole JK
Methionyl-tRNA synthetase zinc binding domain. Three-dimensional structure and homology with rubredoxin and gag retroviral proteins.: J Mol Biol. 1993 Jun 20;231(4):1078-89. Unique Identifier : AIDSLINE MED/93294859; Fourmy D; Dardel F; Blanquet S; Laboratoire de Biochimie, URA 240 CNRS Ecole Polytechnique,; Palaiseau, France.; Methionyl-tRNA synthetase from Escherichia coli contains one tightly bound zinc atom per subunit. The region encompassing residues 138 to 163 of this enzyme is responsible for the metal binding. A 28-mer peptide corresponding to these residues was expressed in vivo and shown to contain approximately 1 mol of tightly b
Crystallization and preliminary X-ray investigation of recombinant simian immunodeficiency virus proteinase.: J Mol Biol. 1993 Jun 20;231(4):1139-42. Unique Identifier : AIDSLINE MED/93294867; Wilderspin AF; Sugrue RJ; Department of Crystallography, Birbeck College, London, U.K.; Simian immunodeficiency virus (SIV) proteinase has been crystallized from sodium acetate buffer with sodium chloride as precipitant. The crystals are orthorhombic and the space group is C222(1) with unit cell dimensions a = 32.18 A, b = 62.52 A, c = 95.76 A, alpha = beta = gamma = 90 degrees, indicating a single monom
[A case of T-cell lymphoma showing multiple nodular shadows and an elevated titer of human T-lymphotropic virus type I (HTLV-I) antibody]: Nippon Kyobu Shikkan Gakkai Zasshi. 1993 Feb;31(2):231-4. Unique Identifier : AIDSLINE MED/93295017; Hanada N; Abe T; Katagiri M; Yanase N; Yamashita E; Shionoya S; Yoshimura H; Kasai K; Kameya T; Tomita T; Department of Medicine, School of Medicine, Kitasato University,; Kanagawa, Japan.; A 42-year-old man, born in Chiba prefecture, was admitted to our hospital because of multiple nodular shadows on chest X-ray film and an elevated titer of human T-lymphotropic virus type I (HTLV-I) antibody. The pulmonary lesion was diagnosed as T-cell lymphoma by open lung biopsy. There has been only one previous rep
[A case of hypersensitivity pneumonitis in Pholiota nameko's manufacturer]: Nippon Kyobu Shikkan Gakkai Zasshi. 1993 Feb;31(2):275-9. Unique Identifier : AIDSLINE MED/93295026; Kishimoto N; Mouri M; Sakurai S; Nanbu Y; Ohya N; Department of Internal Medicine, Kanazawa Medical University,; Ishikawa, Japan.; A 58-year-old female was admitted to our hospital because of fever and dyspnea on exertion. She has been working in the factory making Pholiota nameko for 8 years. Her chest X-ray revealed diffuse linear and fine nodular shadows in both lower lung fields. Hypoxemia was seen on blood gas analysis. Bronchoalveolar lavag
Detection of immunoglobulin gene rearrangement of B cell non-Hodgkin's lymphomas and leukemias in fresh, unfixed and formalin-fixed, paraffin-embedded tissue by polymerase chain reaction.: Lab Invest. 1993 Jun;68(6):746-57. Unique Identifier : AIDSLINE MED/93295088; Inghirami G; Szabolcs MJ; Yee HT; Corradini P; Cesarman E; Knowles DM; Department of Pathology, College of Physicians and Surgeons of; Columbia University, New York, New York.; BACKGROUND: The majority of B cell nonHodgkin s lymphomas (NHLs) are composed of a genotypically identical cell population characterized by a unique immunoglobulin (Ig) VDJ gene rearrangement which is customarily documented by Southern blot hybridization analysis of fresh tissue. Sometimes, however, this approach cann
Immunohistochemical characteristics of polymyositis in patients with HTLV-I-associated myelopathy and HTLV-I carriers.: Muscle Nerve. 1993 May;16(5):472-6. Unique Identifier : AIDSLINE MED/93295406; Higuchi I; Montemayor ES; Izumo S; Inose M; Osame M; Third Department of Internal Medicine, Faculty of Medicine,; Kagoshima University, Japan.; The immunohistochemical characteristics of polymyositis in patients with HTLV-I-associated myelopathy (HAM) and HTLV-I carriers were studied. Infiltrating cells were predominantly T cells and were not different from in the control group. All specimens contained positively staining muscle fibers for MHC class I antigen
Duesberg's anti-AZT campaign continues [news]: Nature. 1993 Jun 24;363(6431):660. Unique Identifier : AIDSLINE MED/93295470; Clayton J
British group backs French scientist [news]: Nature. 1993 Jun 24;363(6431):663. Unique Identifier : AIDSLINE MED/93295471; Dickson D
The SCID-hu mouse as a model for HIV-1 infection.: Nature. 1993 Jun 24;363(6431):732-6. Unique Identifier : AIDSLINE MED/93295486; Aldrovandi GM; Feuer G; Gao L; Jamieson B; Kristeva M; Chen IS; Zack JA; Department of Pediatrics, Harbor, UCLA Medical Center, Torrance; 90509.; During normal fetal ontogeny, one of the first organs to harbour CD4-positive cells is the thymus. This organ could therefore be one of the earliest targets infected by human immunodeficiency virus type 1 (HIV-1) in utero. HIV-1-infected cells and pathological abnormalities of the thymus have been seen in HIV-1-infect
Oral manifestations of cutaneous T-cell lymphoma. A report of eight cases.: Oral Surg Oral Med Oral Pathol. 1993 Jun;75(6):700-5. Unique Identifier : AIDSLINE MED/93295705; Sirois DA; Miller AS; Harwick RD; Vonderheid EC; Department of Oral Pathology, Biology, and Diagnostic Science,; University of Medicine and Dentistry of New Jersey, New Jersey; Dental School, Newark.; Cutaneous T-cell lymphoma rarely involves the oral cavity. Only 14 detailed cases of oral cutaneous T-cell lymphoma have been described in the English-language literature; this report describes eight additional cases observed among 824 patients evaluated at our cutaneous T-cell lymphoma center since 1968. Oral involve
Early oral presentation of lues maligna in a patient with HIV infection. A case report.: Oral Surg Oral Med Oral Pathol. 1993 Jun;75(6):728-32. Unique Identifier : AIDSLINE MED/93295710; Ficarra G; Zaragoza AM; Stendardi L; Parri F; Cockerell CJ; Institute of Odontology and Stomatology, University of Florence,; Italy.; We present a case of a patient infected with the human immunodeficiency virus who developed syphilis manifested by atypical early oral and skin ulcerations. The profound immune defects associated with human immunodeficiency virus may lead to an altered clinical presentation and a more aggressive course in patients inf
Otologic neurotologic manifestations of HIV-related disease.: Otolaryngol Head Neck Surg. 1993 Jun;108(6):680-7. Unique Identifier : AIDSLINE MED/93295730; Linstrom CJ; Pincus RL; Leavitt EB; Urbina MC; Department of Otolaryngology, New York Eye and Ear Infirmary, NY; 10003.; Human immunodeficiency virus (HIV), the causative agent of acquired immunodeficiency syndrome (AIDS), has reached worldwide epidemic proportions and is increasing. Otologists, neurotologists, and audiologists practicing in metropolitan centers in North America can expect to encounter patients with HIV-related illnesse
Improving awareness.: Nurs Times. 1993 May 5-11;89(18):29-31. Unique Identifier : AIDSLINE MED/93295867; McHaffie H
How do colleges approach AIDS/HIV?: Nurs Times. 1993 May 5-11;89(18):56. Unique Identifier : AIDSLINE MED/93295876; McHaffie H; Boyd K
Staff 'just missed routine AIDS tests' [news]: Nurs Times. 1993 May 5-11;89(18):7. Unique Identifier : AIDSLINE MED/93295880
Students 'too scared to reveal they have HIV' [news]: Nurs Times. 1993 May 5-11;89(18):7. Unique Identifier : AIDSLINE MED/93295881; Carlisle D
UKCC policy on AIDS 'must be scrapped' [news]: Nurs Times. 1993 May 26-Jun 1;89(21):7. Unique Identifier : AIDSLINE MED/93295897; Carlisle D
HIV/AIDS. Mind body and soul.: Nurs Times. 1993 Jun 9-15;89(23):42-5. Unique Identifier : AIDSLINE MED/93295908; Sumpter J; Ryan C; Homes-Smith S
Peer pressure threatens HIV precautions [news]: Nurs Times. 1993 Jun 9-15;89(23):9. Unique Identifier : AIDSLINE MED/93295916
Physical and psychosocial nursing care for patients with HIV infection.: Nurs Clin North Am. 1993 Jun;28(2):303-16. Unique Identifier : AIDSLINE MED/93295920; O'Brien ME; Pheifer WG; Catholic University of America School of Nursing, Washington, DC.; As suggested earlier we have chosen in this article to discuss only a small group of key physical and psychosocial concerns and needs associated with HIV and AIDS. These were the issues most frequently discussed by a study group of people living with HIV. We recognize, however, that holistic nursing intervention consi
Delivery systems for the care of persons with HIV infection and AIDS.: Nurs Clin North Am. 1993 Jun;28(2):317-33. Unique Identifier : AIDSLINE MED/93295921; Morrison C; University of California School of Public Health, Berkeley, CA.; HIV infection and AIDS are pathologic conditions that more than any other disease require the concerted, cooperative efforts of the health care profession and the community. This article discusses the development of delivery systems for the care of persons with HIV infection and AIDS, highlights what systems have been
AIDS-myelopathy. A neuropathological study.: Pathol Res Pract. 1993 Feb;189(1):58-65. Unique Identifier : AIDSLINE MED/93296024; Bergmann M; Gullotta F; Kuchelmeister K; Masini T; Angeli G; Department of Neuropathology University of Muenster, FRG.; Vacuolar myelopathy belongs to the AIDS-associated diseases. It is characterized by vacuolation and infiltration of the long tracts of the spinal cord by macrophages. The clinical and morphological findings of 8 AIDS-patients with vacuolar myelopathy are reported here. The syndrome developed during the final stages of
CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals.: Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5549-53. Unique Identifier : AIDSLINE MED/93296175; Mariani R; Skowronski J; Cold Spring Harbor Laboratory, NY 11724.; PCR was used to clone isolates of the human immunodeficiency virus type 1 (HIV-1) nef gene directly from peripheral blood leukocytes of HIV-1-infected individuals. A transient expression system with human CEM T cells was used to assess the effect of nef on CD4 antigen expression on the cell surface. We show that CD4 d
Plasma viremia as a sensitive indicator of the antiretroviral activity of L-697,661.: Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5608-12. Unique Identifier : AIDSLINE MED/93296187; Davey RT Jr; Dewar RL; Reed GF; Vasudevachari MB; Polis MA; Kovacs JA; Falloon J; Walker RE; Masur H; Haneiwich SE; et al; National Institute of Allergy and Infectious Diseases, National; Institutes of Health, Bethesda, MD 20892.; L-697,661 is a non-nucleoside analogue with potent, selective inhibitory activity against the reverse transcriptase of human immunodeficiency virus type 1 (HIV-1). The present study evaluated the potential role of this compound in the treatment of HIV-1-infected patients in a double-blinded, placebo- and zidovudine-co
AIDS and aesthetic surgery [letter]: Plast Reconstr Surg. 1993 Jul;92(1):172-3. Unique Identifier : AIDSLINE MED/93296325; Yoo RP
[Multiple brain lesions with negative serology in cerebrospinal fluid in a patient with AIDS and pulmonary tuberculosis (clinical conference)]: Rev Clin Esp. 1993 May;192(9):451-7. Unique Identifier : AIDSLINE MED/93296494
[Clarithromycin in the treatment of cerebral toxoplasmosis associated with HIV infection (letter)]: Rev Clin Esp. 1993 May;192(9):458-9. Unique Identifier : AIDSLINE MED/93296496; Alba D; Molina F; Ripoll MM; del Arco A
[Visceral leishmaniasis in patients infected by HIV. An AIDS diagnostic criteria? (letter; comment) (published erratum appears in Rev Clin Esp 1993 May;192(9):462)]: Rev Clin Esp. 1993 May;192(9):462. Unique Identifier : AIDSLINE MED/93296500; Rousaud F
[Anesthetic considerations in patients with human immunodeficiency virus infection]: Rev Esp Anestesiol Reanim. 1993 May-Jun;40(3):137-45. Unique Identifier : AIDSLINE MED/93296506; Santacana E; Aliaga L; Villar-Landeira JM; Servicio de Anestesiologia, Reanimacion y Terapeutica del; Dolor, Hospital de la Santa Creu i Sant Pau, Barcelona.; In the last few years many articles have been published on AIDS, the mechanism of transmission, prophylaxis and therapeutic possibilities; however, very few publications are available related with anesthesia of patients infected with HIV or AIDS. The authors have therefore undertaken this review in which following a b
[HIV-induced clinical conditions: rheumatic conditions]: Recenti Prog Med. 1993 Jun;84(6):465-9. Unique Identifier : AIDSLINE MED/93296538; Consoli G; D'Egidio P; Cattedra di Reumatologia, Universita G. D'Annunzio, Pescara.; Many retroviruses have been shown to be involved in the etiology of rheumatic diseases both in animal models and in humans. In particular, HIV infection has been correlated to a greater incidence of Reiter syndrome, psoriatic arthritis, sicca syndrome and other seronegative polyarthritides. Aim of this paper is to dis
Reduction of HIV-1 antigen production by phosphatidylcholine containing formulations via growth inhibition of HIV-1-infected cells.: Res Exp Med (Berl). 1993;193(2):123-35. Unique Identifier : AIDSLINE MED/93296548; Willer A; Heinzmann U; Mellert W; Kleinschmidt A; Goebel FD; Erfle V; GSF-Institut fur Molekulare Virologie, Neuherberg/Munchen,; Germany.; Phosphatidylcholine (PC) and licensed formulations containing PC were tested for their influence on the proliferation and viability of cells permanently infected with HIV-1 (human immunodeficiency virus type 1). PC alone, as well as pharmaceutical formulations containing PC, selectively inhibited the growth of product
What diet can do to combat HIV infection.: RN. 1993 Jun;56(6):71-2. Unique Identifier : AIDSLINE MED/93296639; Cerrato PL
Tuberculosis in the normal host: radiological findings.: Semin Roentgenol. 1993 Apr;28(2):109-18. Unique Identifier : AIDSLINE MED/93296695; Miller WT; Miller WT Jr; Department of Radiology, Hospital of the University of; Pennsylvania, Philadelphia 19104.
Pulmonary tuberculosis in immunocompromised hosts: epidemiological, clinical, and radiological assessment.: Semin Roentgenol. 1993 Apr;28(2):119-30. Unique Identifier : AIDSLINE MED/93296696; Davis SD; Yankelevitz DF; Williams T; Henschke CI; Department of Radiology, New York Hospital-Cornell Medical; Center, NY 10021.
Disseminated nontuberculous mycobacterial infections in immunosuppressed patients.: Semin Roentgenol. 1993 Apr;28(2):150-7. Unique Identifier : AIDSLINE MED/93296699; Aronchick JM; Miller WT Jr; Department of Radiology, University of Pennsylvania Medical; Center, Philaldelphia 19104.; In summary, DNTM is an uncommon cause of infection in non-AIDS immunocompromised patients, but it is seen with increasing frequency as a late complication in AIDS patients who are severely debilitated. Non-AIDS patients may have pulmonary symptoms and parenchymal abnormalities on chest radiographs. These patients appa
Pulmonary tuberculosis in children.: Semin Roentgenol. 1993 Apr;28(2):158-72. Unique Identifier : AIDSLINE MED/93296700; Agrons GA; Markowitz RI; Kramer SS; Department of Radiology, Children's Hospital of Philadelphia, PA; 19104.; TB is no longer the scourge it once was, but it remains an important cause of morbidity and mortality worldwide. Fueled by increasing poverty, homelessness, immigration, drug abuse, declining prevention programs, and the HIV epidemic, its incidence in the United States has increased dr
Rapid freezing of whole blood or buffy coat samples for polymerase chain reaction and cell culture analysis: application to detection of human immunodeficiency virus in blood donor and recipient repositories. The Transfusion Safety Study Group.: Transfusion. 1993 Jun;33(6):504-8. Unique Identifier : AIDSLINE MED/93296814; Adams M; Lee TH; Busch MP; Heitman J; Marshall GJ; Gjerset GF; Mosley JW; Irwin Memorial Blood Centers, San Francisco, California.; Storage of lymphocytes for later use in prospective epidemiologic studies of blood donors and transfusion recipients has been limited by the cost of separating peripheral blood mononuclear cells (PBMCs). When the Transfusion Safety Study began in 1985, it was decided to establish a cell repository of cryopreserved buf
Time from diagnosis of acquired immune deficiency syndrome (AIDS) to death among persons with blood-borne AIDS in Italy.: Transfusion. 1993 Jun;33(6):509-14. Unique Identifier : AIDSLINE MED/93296815; Schinaia N; Bellocco R; Arcieri R; Zaccarelli M; National AIDS Operational Center, Laboratory of Epidemiology and; Biostatistics, Istituto Superiore di Sanita, Rome, Italy.; The objective of the study reported here was to analyze survival time and factors associated with more rapid death among persons with acquired immune deficiency syndrome (AIDS) in Italy who acquired human immunodeficiency virus (HIV) infection through the transfusion of blood (n = 1
Mycobacterial infections in renal allograft recipients.: Transplant Proc. 1993 Jun;25(3):2288-9. Unique Identifier : AIDSLINE MED/93296955; Delaney V; Sumrani N; Hong JH; Sommer B; Department of Surgery, State University of New York Health; Science Center, Brooklyn.
Negative impact of trading in human organs on the development of transplantation in the Middle East.: Transplant Proc. 1993 Jun;25(3):2310-3. Unique Identifier : AIDSLINE MED/93296966; Abouna GM; Department of Surgery, Hahnemann University, Philadelphia,; Pennsylvania 19102.
Omani experience with a heterogeneous group of kidney transplant recipients over a 10-year period.: Transplant Proc. 1993 Jun;25(3):2359-60. Unique Identifier : AIDSLINE MED/93296988; Aghanashinikar PN; Daar AS; Marhuby H; Woods HF; Nandakumar M; Yaqoob M; White AG; Albusaidi QM; al Hassani MK; Oman Transplant Program, Royal Hospital Ministry of Health,; Muscat.
Expression of simian type D retroviral (Mason-Pfizer monkey virus) capsids in insect cells using recombinant baculovirus.: Virology. 1993 Jan;192(1):298-306. Unique Identifier : AIDSLINE MED/93297118; Sommerfelt MA; Roberts CR; Hunter E; University of Alabama at Birmingham, Department of Microbiology,; Birmingham 35294.; Mason- Pfizer monkey virus (M-PMV) is a primate retrovirus that shows type D morphogenesis in mammalian cells. Immature intracytoplasmic A type particles (ICAPs) preassemble in the infected cell cytoplasm migrate to the plasma membrane and are released by budding. This is i
Characterization of a nuclear retention sequence within the 3' region of the HIV-2 envelope gene.: Virology. 1993 Jan;192(1):33-7. Unique Identifier : AIDSLINE MED/93297123; Keller R; Montagnier L; Cordonnier A; Unite d'Oncologie Virale (CNRS UA1157), Institut Pasteur, Paris,; France.; During the phenotypic analysis of mutations in the HIV-2 envelope protein (gp140), we have identified a mutant that expresses high levels of gp140 in the absence of the Rev protein. This mutant was obtained by deletion of a 190-base pair fragment at the end of the env coding region. Northern blot analysis of RNAs prod
Primary HIV-1 isolates refractory to neutralization by soluble CD4 are potently inhibited by CD4-Pseudomonas exotoxin.: Virology. 1993 Jan;192(1):375-9. Unique Identifier : AIDSLINE MED/93297133; Kennedy PE; Moss B; Berger EA; Laboratory of Viral Diseases, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda,; Maryland 20892.; Despite the ability of soluble forms of CD4 (sCD4) and related CD4 derivatives to neutralize human immunodeficiency type 1 (HIV-1) infectivity in vitro, these agents have shown little evidence of efficacy in clinical trials with infected individuals. These disappointing findings may be related to recent observations t
Presence of env genes in members of the RTVL-H family of human endogenous retrovirus-like elements.: Virology. 1993 Jan;192(1):52-61. Unique Identifier : AIDSLINE GENBANK/D11078; Hirose Y; Takamatsu M; Harada F; Department of Biophysics, Cancer Research Institute, Kanazawa; University, Japan.; We have found that the RTVL-H family of human endogenous retrovirus-like elements was highly expressed in lung squamous cell carcinoma tissue and several human cell lines. We determined the nucleotide sequences of several cDNA clones and found a unique sequence that was not present in the published prototypic RTVL-H s
Clinical evaluation of viral safety of coagulation factor VIII and IX concentrates [see comments]: Vox Sang. 1993;64(4):197-203. Unique Identifier : AIDSLINE MED/93297155; Mannucci PM; Angelo Bianchi Bonomi Hemophilia and Thrombosis Center (WHO; Collaborating Center), IRCCS Maggiore Hospital, Milan, Italy.; Virucidal methods to inactivate infectious agents are based on various methods of heating or chemically treating plasma concentrates of coagulation factors VIII and IX used in the treatment of hemophilia A and B. This clinical evaluation of the viral safety of such treated concentrates is mainly based on the prospec
Avoiding indeterminate results in HIV-1 western blot using synthetic peptide assays. HIV-2 Spanish Study Group [letter]: Vox Sang. 1993;64(4):250-1. Unique Identifier : AIDSLINE MED/93297166; Soriano V; Gutierrez M; Tuset C; Martinez-Zapico R; Ortiz de Lejarazu R; Gonzalez A; Aguilera A; Codina G; Ulloa F; Leal M; et al
Association between neopterin and beta-2-microglobulin levels and HIV status in Romanian orphanage children.: Wien Klin Wochenschr. 1993;105(10):284-8. Unique Identifier : AIDSLINE MED/93297172; Zaknun D; DiFranco M; Oswald HP; Zaknun J; Mayersbach P; Vuja E; Wachter H; Fuchs D; Clinic for Paediatrics, University of Innsbruck.; Serologic markers of immune activation, neopterin and beta-2-microglobulin (B2M), have been shown to predict progressive human immunodeficiency virus type 1 (HIV-1) disease based on cohort studies in adults. Both parameters appear also to be valuable in distinguishing HIV-1 infants with progressive disease from asympt
[Effect of cytokines on HIV infection in cell lines]: Wien Klin Wochenschr. 1993;105(10):294-7. Unique Identifier : AIDSLINE MED/93297174; Arabjan E; Sandoz Forschungsinstitut, Wien.
[Increased level of nitrogen radicals in serum of patients with rheumatic diseases and AIDS]: Z Gesamte Inn Med. 1993 May;48(5):244-6. Unique Identifier : AIDSLINE MED/93297184; Zuber M; Miesel R; Deutsches Rheumaforschungszentrum, Berlin.; 354 sera from venous blood of patients with various rheumatic diseases and AIDS were assayed for the presence of reactive nitrogen intermediates. Compared to healthy individuals, the serum levels of nitric oxides from patients with connective tissue diseases and inflammatory rheumatic diseases were elevated (P
Risk of blood contact through surgical gloves in aesthetic procedures.: Aesthetic Plast Surg. 1993 Spring;17(2):167-8. Unique Identifier : AIDSLINE MED/93297367; Greco RJ; Wheatley M; McKenna P; Division of Plastic and Reconstructive Surgery, University of; Pittsburgh, PA 15261.; Evidence of glove perforation, and therefore blood contact, was evaluated in 100 consecutive pairs of gloves used in aesthetic surgical procedures. The surgeon (38.3%) was more likely than the assistant (22.5%) to have exposure. In only 15% of these cases were they aware of the exposure. The left index finger (44%) wa
[Syphilis: current aspects in relation to HIV]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):107-28. Unique Identifier : AIDSLINE MED/93297372; Goens J; De Berdt PA; Services de Dermatologie, Hopitaux Universitaires Saint-Pierre,; Brugmann et des Enfants Reine Fabiola.
[AIDS: myths, untruths and reality]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):15-8. Unique Identifier : AIDSLINE MED/93297376; Clumeck N; Service des Maladies Infectieuses, Hopital Universitaire; Saint-Pierre, Bruxelles.
[History of venereal diseases]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):19-28. Unique Identifier : AIDSLINE MED/93297383; Mattelaer JJ; Service d'Urologie, St.-Maartensziekenhuis, Kortrijk-Belgique.
[Economic impact of HIV]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):29-33. Unique Identifier : AIDSLINE MED/93297397; Souteyrand Y; Agence Nationale de Recherche sur le SIDA, Paris.
[Epidemiology of AIDS in Europe]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):327-35. Unique Identifier : AIDSLINE MED/93297402; Declercq E; Mak R; Stroobant A; Van Hemeldonck LA; Institut d'Hygiene et d'Epidemiologie, Bruxelles.
[Epidemiology of HIV-1 infection and AIDS in developing countries]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):337-9. Unique Identifier : AIDSLINE MED/93297403; Temmerman M; Piot P; W.H.O. Collaborating Center for Research and Training in STD,; Institute of Tropical Medecine, Antwerpen.
[Outpatient management of seropositive patients]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):341-4. Unique Identifier : AIDSLINE MED/93297404; Clumeck N; Centre de reference SIDA-ULB, Hopital Saint-Pierre, Bruxelles.
[Pathophysiology of the HIV virus]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):345-51. Unique Identifier : AIDSLINE MED/93297405; Gerain J; Microbiologie et Medecine Interne, Institut J. Bordet,; Bruxelles.
[Prevention and risk management in economics and medicine: various observations]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):35-9. Unique Identifier : AIDSLINE MED/93297406; Eeckhoudt L; Facultes Universitaires Catholiques de Mons, Belgique.
[Hiv and AIDS infection. A. History, definition and classification]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):353-61. Unique Identifier : AIDSLINE MED/93297407; Cran S; Clinique du Parc Leopold, Bruxelles.
[Natural history of HIV infection in adults]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):363-79. Unique Identifier : AIDSLINE MED/93297408; Cran S; Clinique du Parc Leopold, Bruxelles.
[Opportunistic infections]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):381-93. Unique Identifier : AIDSLINE MED/93297409; Gerard M; Clinique des Maladies Infectieuses, Hopital Saint Pierre,; Bruxelles.
[AIDS and cancer]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):395-8. Unique Identifier : AIDSLINE MED/93297410; Hermans P; Clinique des Maladies Infectieuses, Hopital Universitaire; Saint-Pierre, Bruxelles, Belgique.
[Hematological manifestations of AIDS]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):399-403. Unique Identifier : AIDSLINE MED/93297411; Hamdam O; Gerain J; UCL, Cliniques Universitaires Saint-Luc, Bruxelles.
[The contribution of social sciences to the prevention of AIDS]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):41-6. Unique Identifier : AIDSLINE MED/93297413; Hubert M; Centre d'Etudes Sociologiques, Facultes Universitaires; Saint-Louis, Bruxelles.
[Cardiac manifestations in HIV infection]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):443-8. Unique Identifier : AIDSLINE MED/93297415; Cran S; Clinique du Parc Leopold, Bruxelles.
[Pulmonary manifestations of acquired immunodeficiency syndrome]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):449-72. Unique Identifier : AIDSLINE MED/93297416; Cran S; Clinique du Parc Leopold, Bruxelles.
[Reactions to AIDS risks in heterosexual relations: an attempt at typology]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):47-54. Unique Identifier : AIDSLINE MED/93297417; Van Campenhoudt L; Peto D; Remy J; Hubert M; Centre d'Etudes Sociologiques, Facultes Universitaires; Saint-Louis, Bruxelles.
[Endocrine manifestations of AIDS]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):473-7. Unique Identifier : AIDSLINE MED/93297418; Cran S; Hamdam H; Clinique du Parc Leopold, Bruxelles.
[AIDS and skin]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):479-503. Unique Identifier : AIDSLINE MED/93297419; Delescluse J; Van der Endt H; Service de Dermatologie, Centre Hospitalier Cesar de Paepe,; Bruxelles.
[Digestive manifestations in HIV+ patients. Enteric manifestations and diarrhea]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):505-11. Unique Identifier : AIDSLINE MED/93297420; Van Laethem Y; Service des Maladies Infectieuses, Hopital Universitaire; Saint-Pierre, Bruxelles.
[Hepatobiliary manifestations in acquired immunodeficiency syndrome]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):513-6. Unique Identifier : AIDSLINE MED/93297421; Urbain D; Departement de gastro-enterologie, Hopital universitaire; Saint-Pierre, U.L.B., Bruxelles.
[Anal and perianal lesions observed in subjects infected with HIV virus]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):517-23. Unique Identifier : AIDSLINE MED/93297422; Van Gossum M; Puy-Montbrun T; Ganansia R; Centre Hospitalier Cesar de Paepe, Hopital Universitaire; Brugmann, Bruxelles.
[AIDS and digestive surgery]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):525-9. Unique Identifier : AIDSLINE MED/93297423; Cadiere GB; Bruyns J; Service de Chirurgie Digestive, Hopital Universitaire; Saint-Pierre, Bruxelles.
[Nephrological manifestations of AIDS]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):531-7. Unique Identifier : AIDSLINE MED/93297424; Vandervelde D; Centre d'Hemodialyse, Hospitalier J. Bracops, Bruxelles.
[Urological manifestations in HIV infection]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):539-45. Unique Identifier : AIDSLINE MED/93297425; Libert MH; Centre Hospitalier Cesar de Paepe, Bruxelles.
[Gynecological consequences of HIV infection]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):547-9. Unique Identifier : AIDSLINE MED/93297426; Jacquet C; Service de Gynecologie, Clinique de l'Europe, Bruxelles.
[Definition of sexually transmissible diseases. Relationship between sexually transmitted diseases and HIV infection]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):55-60. Unique Identifier : AIDSLINE MED/93297427; Laga M; Crabbe F; Departement de Microbiologie, Institut de Medecine Tropicale,; Antwerpen, Belgique.
[Rheumatological manifestations of HIV infection]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):551-6. Unique Identifier : AIDSLINE MED/93297428; Golstein M; Mindlin A; Service de Rhumatologie, Centre Hospitalier Cesar De Paepe,; Bruxelles.
[AIDS and ORL manifestations]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):557-66. Unique Identifier : AIDSLINE MED/93297429; Vangehuchten S; Coeckelenbergh A; Verbeurgt L; Service ORL, Centre Hospitalier Cesar de Paepe, Bruxelles.
[Human immunodeficiency virus infection (HIV) in children]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):567-9. Unique Identifier : AIDSLINE MED/93297430; Levy J; Service de Pediatrie, Hopital Universitaire Saint-Pierre.
[Home parenteral nutrition in patients with acquired immunodeficiency syndrome (AIDS)]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):599-606. Unique Identifier : AIDSLINE MED/93297434; Siderova VS; Carpentier YA; Hermans P; Laboratoire de Chirurgie Experimentale L. Deloyers, Universite; Libre de Bruxelles.
[HIV and vaccines]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):607-14. Unique Identifier : AIDSLINE MED/93297435; Payen MC; Service des Maladies Infectieuses, Hopital Universitaire Saint; Pierre, Bruxelles.
[Prevention of HIV infection in the framework of an accidental intramural exposure]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):615-20. Unique Identifier : AIDSLINE MED/93297437; Van Laethem Y; Service des Maladies infectieuses, Hopital Saint-Pierre,; Bruxelles.
[AIDS: Useful addresses]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):621-31. Unique Identifier : AIDSLINE MED/93297438
[Sexually transmissible diseases and medical ethics]: Acta Urol Belg. 1993 Jan-Jun;61(1-2):71-80. Unique Identifier : AIDSLINE MED/93297439; Libert MH; Verdonk G; Urologie, Centre Hospitalier Cesar de Paepe, Bruxelles.
White matter lesions and cerebral atrophy on MR images in patients with and without AIDS dementia complex.: AJR Am J Roentgenol. 1993 Jul;161(1):177-81. Unique Identifier : AIDSLINE MED/93297471; Broderick DF; Wippold FJ 2d; Clifford DB; Kido D; Wilson BS; Mallinckrodt Institute of Radiology, Washington University; Medical Center, St. Louis, MO 63110.; OBJECTIVE. The objective of this study was threefold: to determine if the frequency of deep white matter changes and cerebral atrophy seen on MR images is significantly different between patients with and without AIDS dementia complex, to determine if certain patterns of white matt
APhA launches AIDS education program [news]: Am Pharm. 1993 Jun;NS33(6):59. Unique Identifier : AIDSLINE MED/93297555
New policies of APhA address payment reform, HIV infection, patient compliance [news]: Am J Hosp Pharm. 1993 Jun;50(6):1077, 1081. Unique Identifier : AIDSLINE MED/93297618
Characterization of inflammatory infiltrates in chronic chagasic myocardial lesions: presence of tumor necrosis factor-alpha+ cells and dominance of granzyme A+, CD8+ lymphocytes.: Am J Trop Med Hyg. 1993 May;48(5):637-44. Unique Identifier : AIDSLINE MED/93297664; Reis DD; Jones EM; Tostes S Jr; Lopes ER; Gazzinelli G; Colley DG; McCurley TL; Departamento de Bioquimica e Imunologia, Universidade Federal de; Minas Gerais, Belo Horizonte, Brazil.; The inflammatory infiltrates in the heart lesions of chronic chagasic cardiomyopathy are composed predominantly of small lymphocytes with admixed macrophages, plasma cells, and segmented leukocytes. The phenotypes of the lymphoid cells in these infiltrates of human Chagas disease have not been previously detailed. We
Trends of human immunodeficiency virus type-1 infection in female prostitutes and males diagnosed with a sexually transmitted disease in Djibouti, east Africa.: Am J Trop Med Hyg. 1993 May;48(5):682-6. Unique Identifier : AIDSLINE MED/93297671; Rodier GR; Couzineau B; Gray GC; Omar CS; Fox E; Bouloumie J; Watts D; U.S. Naval Medical Research Unit No. 3, Cairo, Egypt.; A cross-sectional serosurvey for human immunodeficiency virus type 1 (HIV-1) was conducted during the first quarter of 1991 among high risk groups in Djibouti , East Africa, and compared with previous surveys in 1987, 1988, and 1990. The survey demonstrated evidence of HIV-1 infec
Characteristics of the acquired immunodeficiency syndrome in Brazil.: Am J Trop Med Hyg. 1993 May;48(5):687-92. Unique Identifier : AIDSLINE MED/93297672; Moreira Junior ED; Silva N; Brites C; Carvalho EM; Bina JC; Badaro R; Johnson WD Jr; Federal University of Bahia, Salvador, Brazil.; The clinical and epidemiologic characteristics of the acquired immunodeficiency syndrome (AIDS) were studied in a tropical area of Brazil . During an 18-month period (July 1989-January 1991), 111 consecutive AIDS patients (102 men and nine women) were evaluated. Patients reported ho
Cranial computed tomography in the emergency department evaluation of HIV-infected patients with neurologic complaints.: Ann Emerg Med. 1993 Jul;22(7):1169-76. Unique Identifier : AIDSLINE MED/93297766; Tso EL; Todd WC; Groleau GA; Hooper FJ; Division of Emergency Medicine, University of Maryland Medical; Center, Baltimore.; STUDY OBJECTIVE: To demonstrate the usefulness of cranial computed tomography (CT) in the emergency department evaluation of HIV-infected patients and patients with risk factors for HIV infection who present with neurologic complaints. DESIGN: Retrospective review of imaging reports and medical records of patients who
Diffuse microgliosis associated with cerebral atrophy in the acquired immunodeficiency syndrome.: Ann Neurol. 1993 Jul;34(1):65-70. Unique Identifier : AIDSLINE MED/93297905; Gelman BB; Department of Pathology, University of Texas Medical Branch,; Galveston 77550.; The cause of cerebral atrophy in patients with acquired immunodeficiency syndrome (AIDS) is obscure because human immunodeficiency virus type 1 (HIV-1)-related histopathological changes hardly correlate with cerebral atrophy. In this study, brain ventricular expansion was compared to the frontal lobe density of mononu
Pyrimethamine inhibits renal secretion of creatinine.: Antimicrob Agents Chemother. 1993 May;37(5):1056-60. Unique Identifier : AIDSLINE MED/93297921; Opravil M; Keusch G; Luthy R; Division of Infectious Diseases, University Hospital, Zurich,; Switzerland.; The mechanism of increased serum creatinine after administration of pyrimethamine and dapsone was evaluated for six healthy volunteers. Serum parameters, urine sediment, and clearances of creatinine, inulin, and para-aminohippurate were assessed prior to and 28 h after the ingestion of a single, combined dose of 100 m
Standardized peripheral blood mononuclear cell culture assay for determination of drug susceptibilities of clinical human immunodeficiency virus type 1 isolates. The RV-43 Study Group, the AIDS Clinical Trials Group Virology Committee Resistance Working Group.: Antimicrob Agents Chemother. 1993 May;37(5):1095-101. Unique Identifier : AIDSLINE MED/93297927; Japour AJ; Mayers DL; Johnson VA; Kuritzkes DR; Beckett LA; Arduino JM; Lane J; Black RJ; Reichelderfer PS; D'Aquila RT; et al; Division of Infectious Diseases, Beth Israel Hospital, Harvard; Medical School, Boston, Massachusetts 02215.; A standardized antiviral drug susceptibility assay for clinical human immunodeficiency virus type 1 (HIV-1) isolates has been developed for use in clinical trials. The protocol is a two-step procedure that first involves cocultivation of patient infected peripheral blood mononuclear cells (PBMC) with seronegative phyt
Comparative study of bioavailabilities and pharmacokinetics of clindamycin in healthy volunteers and patients with AIDS.: Antimicrob Agents Chemother. 1993 May;37(5):1137-43. Unique Identifier : AIDSLINE MED/93297934; Gatti G; Flaherty J; Bubp J; White J; Borin M; Gambertoglio J; Division of Clinical Pharmacy, School of Pharmacy, University of; California-San Francisco 94143.; The absolute oral bioavailability and pharmacokinetics of clindamycin administered to 16 healthy volunteers and 16 patients with AIDS were compared. Clindamycin was given intravenously (i.v.) (Cleocin phosphate) at a dose of 600 mg as a 25-min infusion and orally (Cleocin hydrochloride) by use of a crossover design in
The prevalence of antibodies to human T-lymphotropic virus type I in different population groups in Papua New Guinea.: Arch Virol. 1993;130(3-4):327-34. Unique Identifier : AIDSLINE MED/93298049; Sanders RC; Wai'in PM; Alexander SS; Levin AG; Blattner WA; Alpers MP; Papua New Guinea Institute of Medical Research, Goroka.; Isolation and partial sequencing of human T-lymphotropic virus type I (HTLV-I) variants from inhabitants of Papua New Guinea (PNG) and the Solomon Is
Phagocytosis reduces HIV-1 production in human monocytes/macrophages infected in vitro.: Arch Virol. 1993;130(3-4):463-9. Unique Identifier : AIDSLINE MED/93298059; Piedimonte G; Montroni M; Silvestri G; Silvotti L; Donatini A; Rossi L; Borghetti AF; Magnani M; Institute of General Pathology, University of Parma, Italy.; The addition of ingestable particles (opsonized erythrocytes or latex beads) or a phorbol ester activates monocytes--derived human macrophages (MDHM) cultured in vitro, and markedly reduces virion release from HIV-infected MDHM as well as their ability to transmit the infection to cocultured lymphoid CD4-positive CEM
Can AIDS be prevented by T-cell vaccination?: Immunol Today. 1993 May;14(5):200-2. Unique Identifier : AIDSLINE MED/93298223; Atlan H; Gersten MJ; Salk PL; Salk J; Service de Biophysique, Centre hospitalier universitaire,; Broussais-Hotel Dieu, Universite Paris VI, France.; T-cell vaccination as a specific prophylactic and therapeutic procedure has been shown to be effective in animal models of autoimmune disease. As autoimmunopathogenic components have been implicated in HIV infection, the authors propose a therapeutic test utilizing T-cell vaccination and suggest that AIDS could be pre
Lymphocyte lifespan, immunological memory and retroviral infections [letter; comment]: Immunol Today. 1993 May;14(5):235. Unique Identifier : AIDSLINE MED/93298231; Michie CA; McLean A
Beating the narcos [interview by Michael Gillard]: Nurs Stand. 1993 May 5-11;7(33):18-9. Unique Identifier : AIDSLINE MED/93298590; Munro E
Poor education undermines profession's HIV work [news]: Nurs Stand. 1993 May 5-11;7(33):8. Unique Identifier : AIDSLINE MED/93298602
Funding cuts to AIDS charities are over hasty [news]: Nurs Stand. 1993 May 12-18;7(34):5. Unique Identifier : AIDSLINE MED/93298615
Neuropathological studies in the brains of AIDS patients with opportunistic diseases.: Int J Legal Med. 1993;105(6):339-50. Unique Identifier : AIDSLINE MED/93298663; Neuen-Jacob E; Figge C; Arendt G; Wendtland B; Jacob B; Wechsler W; Department of Neuropathology, Heinrich-Heine-University,; Dusseldorf, Germany.; The brains of 70 fatal cases with AIDS were studied by means of immunohistochemistry and in-situ hybridization in a consecutive autopsy series (1985-July 1992). In addition, the neuropathological changes were correlated with the neurological and neuroimaging findings. Opportunistic infections included toxoplasmosis (1
[Pulmonary cryptosporidiosis and AIDS. Presentation of a case and review of the literature]: An Med Interna. 1993 May;10(5):232-6. Unique Identifier : AIDSLINE MED/93298833; Brea Hernando AJ; Bandres Franco E; Mosquera Lozano JD; Lantero Benedito M; Ezquerra Lezcano M; Servicio de Medicina Interna, Hospital San Millan, Logrono, La; Rioja.; Pulmonary cryptosporidiasis is a rare disease. However, following the advent of the acquired immunodeficiency syndrome (AIDS), this rare pathology infection by Cryptosporidium and we conduct a literature review. The Cryptosporidium can be detected with the routine technique used for the identification of mycobacterias
[Steroid therapy of non-specific aphthous ulcers in patients with HIV infection (letter)]: An Med Interna. 1993 May;10(5):258-9. Unique Identifier : AIDSLINE MED/93298841; Lopez-Gomez M; Hernandez Burruezo JJ; Castano J; Gea I; Mateas Ruiz F
The interactive role of mucosal T lymphocytes in intestinal growth, development and enteropathy.: J Gastroenterol Hepatol. 1993 May-Jun;8(3):270-8. Unique Identifier : AIDSLINE MED/93298923; Marsh MN; Cummins AG; University Department of Medicine, Hope Hospital, Salford,; Greater Manchester, United Kingdom.; Over the past 15-20 years, research has progressively focused on the mucosal T cell as the central factor in the initiation of physiological or pathological changes, first in the growth and maturation of the early (postnatal) intestine, and second in adult-type enteropathies resulting from sensitivity to either food o
The impact of predators on livestock in the Abruzzo region of Italy.: Rev Sci Tech. 1993 Mar;12(1):39-50. Unique Identifier : AIDSLINE MED/93299001; Fico R; Morosetti G; Giovannini A; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise; G. Caporale, Teramo, Italy.; Free-living populations of wolves (Canis lupus Linnaeus, 1758) and brown bears (Ursus arctos Linnaeus, 1758) regularly cause damage to livestock in the Abruzzo region of Italy . The laws of the region provide for compensation payments to owners for losses caused by predators. In the
[Development of a factual model for the dynamics of the transmission of infection by the human immunodeficiency virus: an example for animal epidemiology]: Rev Sci Tech. 1993 Mar;12(1):73-82. Unique Identifier : AIDSLINE MED/93299003; Le Pont F; Valleron AJ; Institut national de la sante et de la recherche medicale,; Unite de recherches biomathematiques et biostatistiques (U263),; Paris.; In order to simulate the spreading mechanism of human immunodeficiency virus (HIV), a factual approach was developed given the ease of incorporating new knowledge and taking into account the variability of a large number of sociological, biological and demographic factors, and also on account of the dynamics of the re
Vertically transmitted HIV infection in the British Isles.: BMJ. 1993 May 15;306(6888):1296-9. Unique Identifier : AIDSLINE MED/93299143; Ades AE; Davison CF; Holland FJ; Gibb DM; Hudson CN; Nicholl A; Goldberg D; Peckham CS; Department of Epidemiology and Biostatistics, Institute of Child; Health, London.; OBJECTIVE--To describe the epidemiology of vertically acquired HIV infection in the British Isles, the level of underreporting, the vertical transmission rate, and clinical spectrum of paediatric AIDS. DESIGN--Confidential, linked registers based on reporting from obstetricians and paediatricians; anonymous unlinked n
AIDS epidemic in Africa. Channel four tackles controversy [letter] [see comments]: BMJ. 1993 May 15;306(6888):1337. Unique Identifier : AIDSLINE MED/93299153; O'Brien F
Building a city wide service for exchanging needles and syringes.: BMJ. 1993 May 22;306(6889):1394-7. Unique Identifier : AIDSLINE MED/93299189; Gruer L; Cameron J; Elliott L; HIV and Addictions Resource Centre, Ruchill Hospital, Glasgow.; How best can injecting drug misusers obtain clean injecting equipment in a city where drug injecting is widespread? An exchange service for needles and syringes throughout Glasgow has been established in health centres and clinics in the evening. Over the past four years seven new exchanges have been opened and over 2
Injecting drug users in Edinburgh. Fewer drug users share needles [letter; comment]: BMJ. 1993 May 22;306(6889):1414. Unique Identifier : AIDSLINE MED/93299211; Bath GE; Dominy N; Burns SM; Peters A; Davies AG; Richardson AM
Antenatal HIV testing. Anonymous testing misleads patients [letter; comment]: BMJ. 1993 May 29;306(6890):1479. Unique Identifier : AIDSLINE MED/93299256; Kahtan S
Antenatal HIV testing. Dedicated counsellors needed [letter; comment]: BMJ. 1993 May 29;306(6890):1480. Unique Identifier : AIDSLINE MED/93299259; Smith R; Patel NB; Fleming SM
Insurers inconsistent over HIV [news] [see comments]: BMJ. 1993 Jun 5;306(6891):1495-8. Unique Identifier : AIDSLINE MED/93299269
Zidovudine unproved in AIDS dementia [letter; comment]: BMJ. 1993 Jun 5;306(6891):1543-4. Unique Identifier : AIDSLINE MED/93299303; Burgess A; Thornton S; Catalan J
Discriminating needle exchange attenders from non-attenders.: Addiction. 1993 May;88(5):681-7. Unique Identifier : AIDSLINE MED/93299347; Frischer M; Elliott L; Communicable Diseases (Scotland) Unit, Ruchill Hospital, Glasgow,; UK.; In 1990, approximately 1500 of Glasgow s estimated 9400 injecting drug users attended the city s four needle and syringe exchanges. In the same year, a multisite and citywide strategy was used to interview an estimated 5% sample of the city s injectors using an internationally agreed WHO structured schedule. Of the 50
Host factors predisposing to anaerobic infections.: FEMS Immunol Med Microbiol. 1993 Mar;6(2-3):159-63. Unique Identifier : AIDSLINE MED/93299404; Finegold SM; Research Service, VA Medical Center West Los Angeles, Wadsworth,; CA 90073.; Factors that predispose to infection in general, of course, may predispose to infection with anaerobes. Included in this category are diabetes mellitus, neutropenia, hypogammaglobulinaemia, malignancy, splenectomy, collagen vascular disease, cytotoxic drug therapy, corticosteroid therapy and other immunosuppression. H
The HIV quality audit marker (HIV-QAM): an outcome measure for hospitalized AIDS patients.: Qual Life Res. 1993 Apr;2(2):99-107. Unique Identifier : AIDSLINE MED/93299432; Holzemer WL; Henry SB; Stewart A; Janson-Bjerklie S; Department of Mental Health, Community and Administrative; Nursing, School of Nursing, University of California, San; Francisco 94143-0604.; The development and validation of the HIV-Quality Audit Marker (HIV-QAM), an instrument designed to measure changes in the status of hospitalized AIDS patients due to nursing care, is reported. The HIV-QAM is designed to capture the nurse data-collector s judgment of the status of the patient based upon observations,
Suppression by HIV of IL-1 and IL-6 secretion in accessory cells: AC function defect partially corrected with exogenous IL-1 and IL-6.: Clin Immunol Immunopathol. 1993 May;67(2):109-16. Unique Identifier : AIDSLINE MED/93299861; Lacroix F; Zhao DY; Izaguirre CA; Filion LG; Department of Microbiology and Immunology, Faculty of Medicine,; University of Ottawa, Ontario, Canada.; To determine the effect of HIV infection on the accessory cell function of monocytes we measured the ability of HIV-infected monocytes to restore PHA-induced and soluble anti-CD3-induced T cell blastogenesis. These T cells were highly purified and depleted of monocytes (
Detection of HIV in bone allografts prepared from AIDS autopsy tissue.: Clin Orthop. 1993 Jul;(292):384-90. Unique Identifier : AIDSLINE MED/93299915; Salzman NP; Psallidopoulos M; Prewett AB; O'Leary R; Laboratory of Molecular Retrovirology, Georgetown University; School of Medicine, Washington D.C. 20007.; Processed bone from an AIDS patient was tested for the presence of the human immunodeficiency virus type 1 (HIV-1). The preliminary procedures used to process bone allografts included removal of adventitious material and two cycles of freeze thawing. Although infectious virus was readily observed in plasma and bone ma
Leiomyomata and leiomyosarcomata in HIV-infected children [letter; comment]: Diagn Cytopathol. 1993;9(3):366. Unique Identifier : AIDSLINE MED/93299994; Challapalli M
A bacteriological survey of tuberculosis due to the human tubercle bacillus (Mycobacterium tuberculosis) in south-east England: 1984-91.: Epidemiol Infect. 1993 Jun;110(3):609-19. Unique Identifier : AIDSLINE MED/93300141; Yates MD; Grange JM; Public Health Laboratory Service, Dulwich Hospital, London.; The occurrence and nature of bacteriologically confirmed tuberculosis due to Mycobacterium tuberculosis in South-East England in the period 1984-91 is reported and compared with the results of a study for 1977-83. Registered new cases reached a low of 1028 in 1988 but increased to 1252 in 1991. This appeared to be due
Counselling and testing for HIV infection in Rome 1985-1990: analysis of client characteristics and seroprevalence.: Eur J Epidemiol. 1993 Mar;9(2):162-8. Unique Identifier : AIDSLINE MED/93300174; Girardi E; Puro V; Colaiacomo M; Lo Presti E; Frigiotti D; Giannini V; Visco G; Ippolito G; AIDS Unit, Lazzaro Spallanzani Hospital for Infectious Diseases,; Rome, Italy.; To analyze the characteristics of persons seeking HIV testing, and to evaluate the potential effectiveness of a regional program of confidential counselling and testing for HIV infection, we reviewed data on 5127 clients seen from July 1985 to December 1990 in a major counselling and testing site of the city of Rome.
Demand patterns for HIV-tests in general practice: information collected by sentinel networks in 5 European countries.: Eur J Epidemiol. 1993 Mar;9(2):169-75. Unique Identifier : AIDSLINE MED/93300175; Van Casteren V; Leurquin P; Bartelds A; Gurtner F; Massari V; Maurice-Tison S; Vega AT; Mak R; Institute of Hygiene and Epidemiology, Brussels, Belgium.; This study describes a 1 year international data collection on the demand pattern for HIV-antibody tests in general practice recorded by 6 sentinel networks in 5 European countries. The purpose of the recording was to evaluate the use of HIV-antibody testing by general practitioners and the demand for testing among th
AIDS and tuberculosis.: Eur J Epidemiol. 1993 Mar;9(2):176-82. Unique Identifier : AIDSLINE MED/93300176; Morales Suarez-Valera MM; Llopis Gonzalez A; Ballester Calabuig ML; Unidad de Salud Publica, Higiene y Sanidad Ambiental, Burjasot; Valencia, Spain.; Between 1985-1989 were diagnosed 376 cases of TBC in La Fe hospital in Valencia. 36 of this cases also had AIDS. We have carried out a compared study among the 340 cases of TBC and the 36 cases of AIDS+TBC. In this way we have described the social and work conditions of both groups, the hospitalization, the associated
Toxoplasma gondii pneumonia in Italian patients infected with HIV.: Eur J Epidemiol. 1993 Mar;9(2):233-4. Unique Identifier : AIDSLINE MED/93300187; Libanore M; Ghinelli F; Gritti FM; Department of Infectious Diseases, St. Anna Hospital, Ferrara,; Italy.
HIV seroprevalence at the Obstetrics Hospital in Turin, Italy [letter]: Eur J Epidemiol. 1993 Mar;9(2):235-6. Unique Identifier : AIDSLINE MED/93300188; Moiraghi Ruggenini A; Zotti C; Fabris C; Galletto P
Recombinant alpha interferon for chronic hepatitis B in anti-HIV positive patients receiving zidovudine.: Gut. 1993;34(2 Suppl):S106. Unique Identifier : AIDSLINE MED/93300339; Marcellin P; Boyer N; Colin JF; Martinot-Peignoux M; Lefort V; Matheron S; Erlinger S; Benhamou JP; Service d'Hepatologie, Hopital Beaujon, Clichy, France.; In this pilot study of the effects of interferon alfa in 10 anti-HIV positive, chronic hepatitis B patients treated with zidovudine ( AZT ), tolerance to interferon was good and similar to that in anti-HIV negative patients. After treatment, the HIV sta
Zidovudine plus interferon alfa-2b treatment in patients with HIV and chronic active viral hepatitis.: Gut. 1993;34(2 Suppl):S107-8. Unique Identifier : AIDSLINE MED/93300340; Visco G; Alba L; Grisetti S; Guarascio P; Narciso P; Sette P; Struglia C; Tossini G; Tozzi V; L. Spallanzani Hospital for Infectious Diseases, Rome, Italy.; Results are reported for a small study of 11 patients positive for HIV and with chronic active viral hepatitis. Low dose zidovudine/interferon alfa-2b combined treatment produced a general reduction in alanine aminotransferase activities and increased the CD4 lymphocyte count, hepatitis B e seroconversion, and the los
Insurance status among people with AIDS: relationships with sociodemographic characteristics and service use.: Inquiry. 1993 Summer;30(2):180-8. Unique Identifier : AIDSLINE MED/93300557; Fleishman JA; Mor V; Center for Gerontology and Health Care Research, Brown; University.; This paper presents data on health insurance coverage among people with AIDS. The data came from interviews with 937 people with AIDS recruited from outpatient HIV clinics and community-based AIDS service organizations in nine communities across the United States . At the time of the in
Transfusion therapy in the critically ill patient.: Int Anesthesiol Clin. 1993 Spring;31(2):73-95. Unique Identifier : AIDSLINE MED/93300581; Chanatry BJ; Gettinger A
AIDS in India [letter]: Home Healthc Nurse. 1993 May-Jun;11(3):71-2. Unique Identifier : AIDSLINE MED/93300672; Campbell D
No link: HIV and CFS [news]: J Am Osteopath Assoc. 1993 May;93(5):542. Unique Identifier : AIDSLINE MED/93300687
Vaccines tested in HIV-infected children [news]: J Am Osteopath Assoc. 1993 May;93(5):542. Unique Identifier : AIDSLINE MED/93300688
Nucleolar targeting signal of Rex protein of human T-cell leukemia virus type I specifically binds to nucleolar shuttle protein B-23.: J Biol Chem. 1993 Jul 5;268(19):13930-4. Unique Identifier : AIDSLINE MED/93300776; Adachi Y; Copeland TD; Hatanaka M; Oroszlan S; Laboratory of Molecular Virology and Carcinogenesis, National; Cancer Institute-Frederick Cancer Research and Development; Center, Frederick, Maryland 21702-1201.; Rex protein, the post-transcriptional regulator of human T-cell leukemia virus type I, is located predominantly in the cell nucleolus and is associated with the cytoplasmic accumulation of unspliced and singly spliced viral mRNAs. The N-terminal 19-amino acid segment of Rex has been identified as the nucleolar targeti
Lymphocyte subsets and serum immunoglobulins in patients with premature ovarian failure before and after oestrogen replacement.: Hum Reprod. 1993 May;8(5):714-6. Unique Identifier : AIDSLINE MED/93301073; Ho PC; Tang GW; Lawton JW; Department of Obstetrics and Gynaecology, University of Hong; Kong.; We have previously demonstrated that in patients with oestrogen deficiency, there was a significant reduction in the ratio of CD4+ to CD8+ lymphocytes. To test our hypothesis that oestrogen deficiency was the cause of the changes in lymphocyte subsets, we have studied the lymphocyte subsets and serum immunoglobulin le
Enzyme-linked oligosorbent assay for detection of polymerase chain reaction-amplified human immunodeficiency virus type 1.: J Clin Microbiol. 1993 Jun;31(6):1444-9. Unique Identifier : AIDSLINE MED/93301098; Mallet F; Hebrard C; Brand D; Chapuis E; Cros P; Allibert P; Besnier JM; Barin F; Mandrand B; Unite Mixte de Recherche 103, Centre National de la Recherche; Scientifique-bioMerieux, Ecole Normale Superieure de Lyon,; France.; An enzyme-linked oligosorbent assay (ELOSA) was developed for the detection on microtiter plates of polymerase chain reaction (PCR)-amplified human immunodeficiency virus type 1 (HIV-1) DNA. The denatured PCR product was hybridized with a passively adsorbed oligonucleotide capture probe and a horseradish peroxidase-la
Discrimination between human T-cell lymphotropic virus type I and II (HTLV-I and HTLV-II) infections by using synthetic peptides representing an immunodominant region of the core protein (p19) of HTLV-I and HTLV-II.: J Clin Microbiol. 1993 Jun;31(6):1481-5. Unique Identifier : AIDSLINE MED/93301104; Bonis J; Baillou A; Barin F; Verdier M; Janvier B; Denis F; Laboratoire de Bacteriologie-Virologie, Centre Hospitalier; Universitaire Dupuytren, Limoges, France.; We describe enzyme immunoassays that use synthetic oligopeptides to discriminate serologically between human T-cell lymphotropic virus type I and II (HTLV-I and HTLV-II) infections. The peptides represented 20-amino acid segments between residues 111 and 130 (MA1) and residues 116 and 135 (MA2) of the p19 gag proteins
Increased detection of human immunodeficiency virus antigenemia after dissociation of immune complexes at low pH.: J Clin Microbiol. 1993 Jun;31(6):1656-8. Unique Identifier : AIDSLINE MED/93301140; Pokriefka RA; Manzor O; Markowitz NP; Saravolatz LD; Kvale P; Donovan RM; Department of Internal Medicine, Henry Ford Hospital, Detroit,; Michigan 48202.; This study compared the number of patients with detectable human immunodeficiency virus (HIV) antigenemia after immune complex (IC) dissociation by established methods using either 0.5 NCl or 1.5 M glycine buffer. Without IC dissociation, HIV antigen was detected in 43% of patients. After dissociation, the HCl method
Progress in the understanding of HIV infection: an overview.: J Am Acad Dermatol. 1993 Jul;29(1):1-21. Unique Identifier : AIDSLINE MED/93301194; Myers SA; Prose NS; Bartlett JA; Department of Dermatology, Duke University Medical Center,; Durham, NC 27710.; The worldwide epidemic of human immunodeficiency virus (HIV) infection will likely be considered the most important public health event of the twentieth century. During the past 15 years, a wealth of information relating to the epidemiology, diagnosis, natural history, and treatment of HIV infection has accumulated. T
Clinical curriculum considerations for an HIV seropositive dental student.: J Dent Educ. 1993 Jun;57(6):449-53. Unique Identifier : AIDSLINE MED/93301249; Dale RA; Berrong JM; Kuebker WA; Department of General Practice; University of Texas Health; Science Center, San Antonio 78284.
Neurosyphilis with associated retinitis.: J Am Optom Assoc. 1993 Apr;64(4):245-9. Unique Identifier : AIDSLINE MED/93301350; Ruder AJ; Halverson KD; Austin JK; Jones WL; A 59-year-old black male presented with an acute unilateral central scotoma and decreased visual acuity in each eye. Ocular examination revealed bilateral vitritis, nerve fiber layer hemorrhages and infarcts, arteritis, serous macular edema and optic nerve head edema with telangiectasia. Vascular work-up was remarkabl
[Investigation of AZT sensitivity of HIV-1 isolates from patients treated with AZT]: Kansenshogaku Zasshi. 1993 Apr;67(4):311-4. Unique Identifier : AIDSLINE MED/93301474; Saito T; Kondo M; Ito A; Nagao T; Imai M; Department of Virology, Kanagawa Prefectural Public Health; Laboratories.; AZT sensitivity was investigated on 6 HIV-1 isolates by culture method. Three of the isolates derived from 2 patients treated with AZT and the others were isolated from patients not treated with AZT. Cultures of 2 isolates (005 and 038) from a patient
Failure to establish long-term marrow cultures from immunodeficient mice (MAIDS): effect of zidovudine in vitro.: J Leukoc Biol. 1993 Jun;53(6):658-65. Unique Identifier : AIDSLINE MED/93301555; Tse KF; Hughes NK; Gallicchio VS; Department of Medicine, University of Kentucky Medical Center,; Lexington.; We report here the results of studies examining the ability of zidovudine ( AZT ) to influence the establishment and maintenance of long-term marrow cultures (LTMC) using marrow from murine immunodeficient mice (MAIDS). Normal C57BL6 mice were infected
Uniform detection of HIV-1 in alveolar macrophages of pediatric but not adult AIDS patients.: J Leukoc Biol. 1993 Jun;53(6):722-6. Unique Identifier : AIDSLINE MED/93301564; Pearce TE; Nowakowski M; Eden E; Huang ZB; Steiner P; Shahabuddin M; Potash MJ; Volsky DJ; Molecular Virology Laboratory, St. Luke's/Roosevelt Hospital; Center, College of Physicians and Surgeons, Columbia University,; New York, New York 10019.; Manifestations of pulmonary disease in pediatric AIDS patients differ from those in adults. To evaluate whether differences in the frequency of alveolar macrophage (AM) infection with human immunodeficiency virus type 1 (HIV-1) could account for these clinical distinctions, we undertook a comparative analysis of HIV-1
Effects of adjuvants and multiple antigen peptides on humoral and cellular immune responses to gp160 of HIV-1.: J Acquir Immune Defic Syndr. 1993 Aug;6(8):855-64. Unique Identifier : AIDSLINE MED/93301828; Levi M; Ruden U; Birx D; Loomis L; Redfield R; Lovgren K; Akerblom L; Sandstrom E; Wahren B; Department of Virology, National Bacteriological Laboratory,; Stockholm, Sweden.; The capacity of five different adjuvants, AlPO4, a muramyldipeptide formulation (MDP.TSL), Freund s adjuvant, immunostimulating complex and its matrix components to elicit humoral and cellular responses in rabbits immunized with the human immunodeficiency virus type 1 (HIV-1) envelope protein rgp160IIIB was compared.
Induction of HIV-1 replication in a chronically infected T-cell line by cytotoxic T lymphocytes.: J Acquir Immune Defic Syndr. 1993 Aug;6(8):865-71. Unique Identifier : AIDSLINE MED/93301829; Harrer T; Jassoy C; Harrer E; Johnson RP; Walker BD; Infectious Disease Unit, Massachusetts General Hospital, Boston; 02114.; CD8-positive cytotoxic T cells (CTLs) are activated by recognition of peptide bound to MHC class I molecules on target cells. This human leukocyte antigen-restricted process induces not only lysis of target cells but also secretion of lymphokines by the CTLs, including TNF-alpha, TNF-beta, and IFN-gamma. In this study
Zidovudine resistance, syncytium-inducing phenotype, and HIV disease progression in a case-control study. The VA Cooperative Study Group.: J Acquir Immune Defic Syndr. 1993 Aug;6(8):891-7. Unique Identifier : AIDSLINE MED/93301832; St Clair MH; Hartigan PM; Andrews JC; Vavro CL; Simberkoff MS; Hamilton JD; Burroughs Wellcome Co., Research Triangle Park, North Carolina; 27709.; A case-control study of patients with progressive (cases) or nonprogressive (controls) disease was designed to determine the association among disease progression, zidovudine sensitivity, and syncytium-inducing phenotype. Viral isolates were screened for sensitivity to zidovudine using a peripheral blood mononuclear c
Prevalence and persistence of antibody titers to recombinant HIV-1 core and matrix proteins in HIV-1 infection.: J Acquir Immune Defic Syndr. 1993 Aug;6(8):898-903. Unique Identifier : AIDSLINE MED/93301833; Janvier B; Mallet F; Cheynet V; Dalbon P; Vernet G; Besnier JM; Choutet P; Goudeau A; Mandrand B; Barin F; Unite de Virologie, URA CNRS 1334, CHRU Bretonneau, Tours,; France.; Numerous studies have established the correlation between antibodies to the core protein p24 of HIV-1 and the progression of the acquired immunodeficiency syndrome. In this study, we analyzed the immune response to two recombinant gag proteins, p24 and p17, in order to evaluate their diagnostic or prognostic significa
Pharmacoepidemiology of adverse drug reactions in hospitalized patients with human immunodeficiency virus disease.: J Acquir Immune Defic Syndr. 1993 Aug;6(8):919-26. Unique Identifier : AIDSLINE MED/93301836; Harb GE; Alldredge BK; Coleman R; Jacobson MA; Department of Medicine, University of California, San Francisco.; To evaluate the incidence, characteristics, and risk factors of adverse drug reactions (ADRs) in patients with human immunodeficiency virus (HIV) disease, we conducted was a prospective observational study of inpatients with HIV disease. The study was conducted in a public teaching hospital affiliated with the Univers
Chromosome studies in HTLV-I, -II, and HIV-1, -2 cell lines infected in vivo and in vitro.: J Acquir Immune Defic Syndr. 1993 Aug;6(8):930-40. Unique Identifier : AIDSLINE MED/93301838; Whang-Peng J; Chen YM; Knutsen T; Zhao WP; Tsai S; Medicine Branch, National Cancer Institute, National Institutes; of Health, Bethesda, Maryland 20892.; HTLV-I, II and HIV-1, 2 are T-cell tropic viruses, all belonging to the retrovirus family. These viruses are transmitted horizontally by intimate contact or through blood products. The study of chromosomal changes in these T cells may enhance our understanding of the nature and mechanism of these viral infections. How
HIV-2 infection in Bissau, West Africa, 1987-1989: incidence, prevalences, and routes of transmission.: J Acquir Immune Defic Syndr. 1993 Aug;6(8):941-8. Unique Identifier : AIDSLINE MED/93301839; Poulsen AG; Aaby P; Gottschau A; Kvinesdal BB; Dias F; Molbak K; Lauritzen E; Statens Seruminstitut, Copenhagen, Denmark.; In a community study, the HIV-1 and HIV-2 antibody status of the inhabitants of 100 randomly chosen houses in Bissau, West Africa, were followed from 1987 to 1989. There was no HIV-1 infection alone, while the HIV-2 seroprevalence in adults was 8.9% (58 of 652) in 1987 and 10.1% (61 of 603) in 1989. HIV-2 seroprevalen
Seroepidemiology of human T-cell lymphotropic virus type I/II in northeastern Brazil.: J Acquir Immune Defic Syndr. 1993 Aug;6(8):959-63. Unique Identifier : AIDSLINE MED/93301841; Moreira ED Jr; Ribeiro TT; Swanson P; Sampaio Filho C; Melo A; Brites C; Badaro R; Toedter G; Lee H; Harrington W Jr; Department of Medicine, Federal University of Bahia, Salvador,; Brazil.; We investigated the prevalence of human T-lymphotropic virus I/II (HTLV-I/II) infection in Bahia, a state in Northeastern Brazil . Healthy individuals (n = 327) and patients (n = 337) with a variety of diseases were screened for antibodies to HTLV-I/II using an enzyme immunoassay an
Prevalence of anti-HTLV-I antibodies in HIV-seropositive individuals in Guadalajara, Mexico [letter]: J Acquir Immune Defic Syndr. 1993 Aug;6(8):965-6. Unique Identifier : AIDSLINE MED/93301843; Vazquez-Valls E; Campos-Lopez PI; Torres-Mendoza BM; Alvarez-Maya I; Gonzalez-Mendoza A
AIDS cases with wasting syndrome who meet the CDC surveillance criteria [letter]: J Acquir Immune Defic Syndr. 1993 Aug;6(8):966-7. Unique Identifier : AIDSLINE MED/93301844; Nwanyanwu OC; Nahlen BL; Stehr-Green JK; Berkelman RL
Detection of anti-HIV antibodies in saliva.: J Oral Pathol Med. 1993 Apr;22(4):153-6. Unique Identifier : AIDSLINE MED/93301857; Urquia M; Rodriguez-Archilla A; Gonzalez-Moles MA; Ceballos A; Department of Oral Medicine, University of Granada, Spain.; It is sometimes difficult in clinical practice to identify carriers of the AIDS virus. Such identification is of unquestionable value in oral pathology, both for determining the pathogenesis of certain lesions and for assessing their significance to the patient. We evaluated several commercially available diagnostic t
Immunohistochemical study of oral keratoses including lichen planus.: J Oral Pathol Med. 1993 Apr;22(4):180-2. Unique Identifier : AIDSLINE MED/93301862; Robertson WD; Wray D; Department of Oral Medicine & Oral Pathology, University of; Edinburgh, Scotland.; Biopsies of non-ulcerated oral mucosa from 13 patients with oral lichen planus and 12 patients with leukoplakia were immunohistochemically stained using monoclonal antibodies to pan T, pan B, T helper and T suppressor/cytotoxic cells and the stained lymphocytes enumerated using an image analyser. The results show the
Langerhans cells: structure, function and role in oral pathological conditions.: J Oral Pathol Med. 1993 May;22(5):193-202. Unique Identifier : AIDSLINE MED/93301865; Lombardi T; Hauser C; Budtz-Jorgensen E; Division of Gerodontology and Removable Prosthodontics,; University of Geneva, Switzerland.; Langerhans cells (LCs) are dendritic bone marrow derived cells situated suprabasally in most stratified squamous epithelia, such as the epidermis and the epithelium of oral mucosa, including the gingiva. Langerhans cells are thought to act as antigen-presenting cells (APC) during induction of immune responses. The exa
Salivary autoantibodies in HIV-associated salivary gland disease.: J Oral Pathol Med. 1993 May;22(5):203-6. Unique Identifier : AIDSLINE MED/93301866; Atkinson JC; Schiodt M; Robataille S; Greenspan D; Greenspan JS; Fox PC; Clinical Investigations Section, National Institute of Dental; Research, Bethesda, Maryland 20892.; A subset of HIV-positive patients develops salivary gland disease (HIV-SGD), characterized by salivary gland enlargement and/or decreased salivary flow. While clinical symptoms are similar to Sjogren s syndrome (SS), patients with HIV-SGD lack circulating anti-SS-A/Ro and anti-SS-B/La. Occasionally, SS patients lackin
Oral mucosal bacillary epithelioid angiomatosis in a patient with AIDS associated with rapid alveolar bone loss: case report.: J Oral Pathol Med. 1993 May;22(5):235-9. Unique Identifier : AIDSLINE MED/93301872; Glick M; Cleveland DB; Infectious Disease Center, Temple University School of Dentistry,; Philadelphia, PA 19140.; Oral manifestations of bacillary epithelioid angiomatosis have been described in the literature, but without histopathologic evidence confirming the presence of the etiologic bacilli. The clinical and histopathologic similarities between bacillary epithelioid angiomatosis and Kaposi s sarcoma may have contributed to c
Infectious diseases.: JAMA. 1993 Jul 14;270(2):223-4. Unique Identifier : AIDSLINE MED/93302024; Stoeckle MY; Douglas RG Jr; Cornell University Medical College, New York, NY.
HIV/AIDS early treatment controversy cues new advice but questions remain [news]: JAMA. 1993 Jul 21;270(3):295-6. Unique Identifier : AIDSLINE MED/93302045; Goldsmith MF
Commission report: 'AIDS: an expanding tragedy' [news]: JAMA. 1993 Jul 21;270(3):298. Unique Identifier : AIDSLINE MED/93302047; Marwick C
From the Centers for Disease Control and Prevention. Update: mortality attributable to HIV infection/AIDS among persons aged 25-44 years--United States, 1990 and 1991.: JAMA. 1993 Jul 21;270(3):305-6. Unique Identifier : AIDSLINE MED/93302050
[Thrombocytopenia in HIV-1 seropositive hemophiliacs]: Rinsho Ketsueki. 1993 May;34(5):605-10. Unique Identifier : AIDSLINE MED/93302133; Fukutake K; Yorifuji H; Koike K; Yamamoto Y; Tateyama M; Sugimura D; Yoshida S; Takahashi Y; Department of Clinical Pathology, Tokyo medical College.; When platelet counts were compared in 1986 and 1992 in 117 anti-HIV antibody positive and negative hemophilia patients, a clear decrease was found in the positive group. In 1992 platelet counts
[Detection of HIV-1 proviral DNA and RNA in serum from HIV-1 sero-positive hemophiliacs by polymerase chain reaction]: Rinsho Ketsueki. 1993 May;34(5):620-7. Unique Identifier : AIDSLINE MED/93302136; Horikoshi Y; Ichikawa M; Tonouchi T; Mimaya J; Morita T; Ohtsuka Y; Kawabata H; Division of Hematology and Oncology, Shizuoka Children's; Hospital.; We amplified HIV-1 proviral DNA and RNA in serum by DNA-PCR and RT-RCR in 20 HIV-1 seropositive hemophiliacs asymptomatic carrier (AC): 10, AIDS-related complex (ARC):8, AIDS:2). HIV-1 DNA sequences were identified in 44 (93.6%) of 47 specimens. 23 (92.0%) of 25 samples in AC, 13 (100%) of 13 in ARC, 8 (88.8%) of 9 in
Viral DNA in microdissected renal biopsy tissue from HIV infected patients with nephrotic syndrome.: Kidney Int. 1993 Jun;43(6):1347-52. Unique Identifier : AIDSLINE MED/93302261; Kimmel PL; Ferreira-Centeno A; Farkas-Szallasi T; Abraham AA; Garrett CT; Department of Medicine, George Washington University Medical; Center, Washington, D.C.; Focal glomerulosclerosis (FGS) has been considered as HIV-associated nephropathy, a specific renal complication of infection. To determine whether renal disease in HIV infected patients has one highly prevalent pathologic expression, and whether renal parenchymal viral genomic incorporation affects pathologic outcome,
[Risk of tuberculosis in parenteral drug addicts with human immunodeficiency virus seropositivity. A cohort study in detoxication communities]: Med Clin (Barc). 1993 May 15;100(19):725-9. Unique Identifier : AIDSLINE MED/93302287; Solera J; Lopez E; Serna E; Vergara L; Martinez-Alfaro E; Saez L; Unidad de Enfermedades Infecciosas, Hospital General de Albacete.; BACKGROUND: The aim of this study was to determine the risk of active tuberculosis in intravenous drug addict (IVDA) patients seropositive and seronegative for the HIV. METHODS: A retrospective study of a cohort of IVDA males in 2 drug addict detoxication communities was carried out. Patients with tuberculosis, under
[Recurrent abscess of the lung caused by Rhodococcus equi in an HIV-positive patient: response to the combination imipenem/vancomycin (letter)]: Med Clin (Barc). 1993 May 15;100(19):759. Unique Identifier : AIDSLINE MED/93302297; Javaloyas M; Garcia D; Ruffi G
[Bacillary (epithelioid) angiomatosis with a nodular presentation and self-limited evolution]: Med Clin (Barc). 1993 Jun 12;101(3):102-4. Unique Identifier : AIDSLINE MED/93302312; Teira R; Lopez I; Zubero Z; Munoz J; Careaga JM; Santamaria JM; Servicios de Anatomia Patologica, Hospital Civil de Bilbao.; Bacillary angiomatosis (epithelioid) is a recently described clinicopathologic syndrome, principally associated to infection by the human immunodeficiency virus. The case of a patient who was seen for fever and the appearance of four painful, erythematous and indurated subcutaneous nodules on the anteroexternal face o
[Serum adenosine deaminase and HIV infection (letter; comment)]: Med Clin (Barc). 1993 Jun 12;101(3):115. Unique Identifier : AIDSLINE MED/93302315; Jaqueti J; Martinez-Hernandez D; Arenas J; Gomez de Terreros FJ
[The seroprevalence of human immunodeficiency virus infection (letter; comment)]: Med Clin (Barc). 1993 Jun 12;101(3):115-6. Unique Identifier : AIDSLINE MED/93302316; Casabona J; Vall M
[Swedish protection against infections and HIV-positive blacks]: Lakartidningen. 1993 Jun 30;90(26-27):2467-8. Unique Identifier : AIDSLINE MED/93302391; Britton S; Institutionen for infektionssjukdomar, Huddinge sjukhus.
[Prevalence of HIV-positive persons is high in groups of Africans]: Lakartidningen. 1993 Jun 30;90(26-27):2468-9. Unique Identifier : AIDSLINE MED/93302392; Christenson B; Lundbergh P; Smittskyddslakare, Karolinska sjukhuset, Stockholm.
HTLV-I among Northern Territory aborigines [see comments]: Med J Aust. 1993 Jul 5;159(1):12-6. Unique Identifier : AIDSLINE MED/93302567; Bastian I; Hinuma Y; Doherty RR; Menzies School of Health Research, Casuarina, NT.; OBJECTIVE: To survey the Aboriginal community of the Northern Territory for antibodies to human T-lymphotropic virus type I (HTLV-I) and to describe the distribution of the virus. DESIGN: A sero-epidemiological study using the Serodia particle-agglutination assay, indirect immunofluorescence and western blot. Evidence
Tropical spastic paraparesis in an aborigine [see comments]: Med J Aust. 1993 Jul 5;159(1):28-9. Unique Identifier : AIDSLINE MED/93302572; Rajabalendaran N; Burns R; Mollison LC; Blessing W; Kirubakaran MG; Lindschau P; Department of Medicine, Alice Springs Hospital, NT.; OBJECTIVE: To present the first documented case of human T-lymphotropic virus type I (HTLV-I) associated myelopathy/tropical spastic paraparesis in the Australian population. CLINICAL FEATURES: A 31-year-old Aboriginal man with an 18-month history of progressive weakness of the legs was found to have an upper motor ne
HTLV-I associated myelopathy in a Seychellois immigrant.: Med J Aust. 1993 Jul 5;159(1):29-31. Unique Identifier : AIDSLINE MED/93302573; Thyagarajan D; Bastian I; Stark RJ; Day BJ; Dax EM; Gilligan BS; Department of Neurology, Alfred Hospital, Prahran, VIC.; OBJECTIVE: To describe the clinical and laboratory features of human T-lymphotropic virus type I (HTLV-I) associated myelopathy in an immigrant from the Seychelles . CLINICAL FEATURES: A slowly progressive myelopathy has been recently diagnosed in a 64-year-old woman who emigrat
HTLV-I in Australia [editorial; comment]: Med J Aust. 1993 Jul 5;159(1):3-4. Unique Identifier : AIDSLINE MED/93302574; Heard RN; Department of Neurology, Royal Prince Alfred Hospital, Sydney.
HTLV-I: is donor screening really necessary? [editorial; comment]: Med J Aust. 1993 Jul 5;159(1):4-5. Unique Identifier : AIDSLINE MED/93302577; Wylie B; New South Wales Red Cross Blood Transfusion Service.
HTLV-I among Northern Territory blood donors [see comments]: Med J Aust. 1993 Jul 5;159(1):7-12. Unique Identifier : AIDSLINE MED/93302599; Bastian I; Dent J; McFarlane R; Karopoulos A; Way B; Menzies School of Health Research, Casuarina, NT.; OBJECTIVE: Human T-lymphotropic virus type I (HTLV-I) is known to be endemic among Northern Territory (NT) Aborigines, therefore evidence was sought of HTLV-I infection in NT blood donors. DESIGN: Samples were screened for HTLV-I antibodies using the Serodia HTLV-I particle-agglutination assay. Repeatedly reactive ser
'U' discovers transmission of AZT-resistant AIDS [news]: Minn Med. 1993 Jun;76(6):50. Unique Identifier : AIDSLINE MED/93302642
Acer may have transmitted AIDS to another Florida patient [news]: Minn Med. 1993 Jun;76(6):50-1. Unique Identifier : AIDSLINE MED/93302643
AIDS cases continue to grow [news]: Minn Med. 1993 Jun;76(6):51. Unique Identifier : AIDSLINE MED/93302644
AIDS vaccine for mothers may protect newborns [news]: Minn Med. 1993 Jun;76(6):51. Unique Identifier : AIDSLINE MED/93302645
Retrospective serological study of histoplasmosis in Mexico.: Mycoses. 1993 Jan-Feb;36(1-2):25-30. Unique Identifier : AIDSLINE MED/93302806; Taylor ML; Pedroza-Seres M; Gamez-Aranda A; Toriello C; Department of Microbiology and Parasitology, School of Medicine,; National Autonomous University of Mexico, D. F.; Mycotic immunodiagnosis was performed in 325 patients with clinical evidence of systemic mycoses, over a 5-year period, from different hospitals of Mexico City. Results showed 168 individuals that presented one positive serological test to Histoplasma capsulatum antigens. From these, only 27 patients were serologicall
CLIA-88 and OSHA--the price of compliance for Physicians' Office Laboratories.: Nebr Med J. 1993 May;78(5):124-7. Unique Identifier : AIDSLINE MED/93302872; Loschen DJ
[Acute non-lithiasic cholecystitis caused by Salmonella enteritidis in AIDS (letter)]: Presse Med. 1993 May 1-8;22(16):785. Unique Identifier : AIDSLINE MED/93303151; Thyrault M; Gachot B; Wolff M
[Value of polymerase chain reaction in the detection of HIV infection in tissue donors (letter)]: Presse Med. 1993 May 1-8;22(16):787. Unique Identifier : AIDSLINE MED/93303155; Loty B
Renal manifestations of AIDS.: Radiographics. 1993 May;13(3):587-96. Unique Identifier : AIDSLINE MED/93303322; Miller FH; Parikh S; Gore RM; Nemcek AA Jr; Fitzgerald SW; Vogelzang RL; Department of Radiology, Northwestern University Medical School,; Northwestern Memorial Hospital, Chicago, Ill.; The kidneys in patients with acquired immunodeficiency syndrome (AIDS) are subject to a variety of insults. Renal manifestations can be seen with imaging studies of AIDS patients. Computed tomographic (CT) and ultrasound (US) scans of 64 patients with AIDS and renal dysfunction were retrospectively reviewed and compar
[From knowledge on sex behavior to AIDS prevention (editorial)]: Rev Epidemiol Sante Publique. 1993;41(3):197-9. Unique Identifier : AIDSLINE MED/93303370; Spira A
[Factors associated with at-risk anal relations in homosexual HIV-seropositive men]: Rev Epidemiol Sante Publique. 1993;41(3):228-34. Unique Identifier : AIDSLINE MED/93303374; Nadeau D; Boyer R; Fortin C; Duval B; Godin G; Bergeron M; Unite de Recherche Clinique pour le Traitement du Sida, Ste-Foy,; Canada.; This pilot study proposes an index to quantify the intensity of high-risk anal sex and presents factors associated with this practice among 65 homosexual men with HIV infection. All of them answered a self-administered questionnaire. Using multiple logistic regression, we first compared those who had had safe sex in t
Lethal cascade. A model for the neurologic damage found in AIDS.: Sci Am. 1993 Mar;268(3):28-30. Unique Identifier : AIDSLINE MED/93303580; Holloway M
NIH to test AIDS drug nixed by WHO [news]: Science. 1993 Jun 25;260(5116):1880. Unique Identifier : AIDSLINE MED/93303586; Holden C
Army expected to clear AIDS scientist [news]: Science. 1993 Jul 2;261(5117):19. Unique Identifier : AIDSLINE MED/93303614
Shalala draws line on AIDS test royalties [news]: Science. 1993 Jul 2;261(5117):19. Unique Identifier : AIDSLINE MED/93303615
Donna Shalala and the future of NIH [news]: Science. 1993 Jul 2;261(5117):20-1. Unique Identifier : AIDSLINE MED/93303616; Mervis J
Blood transfusion and viruses with delayed expression [editorial]: S Afr Med J. 1993 Apr;83(4):235-6. Unique Identifier : AIDSLINE MED/93303710; Nurse GT
Rapid 'bedside' HIV tests and testing--useful but needs to be used with caution [letter]: S Afr Med J. 1993 Apr;83(4):294. Unique Identifier : AIDSLINE MED/93303732; Evian C
A Pandora's box of hiv testing [letter]: S Afr Med J. 1993 Apr;83(4):294-5. Unique Identifier : AIDSLINE MED/93303733; Lyons SF; Martin DJ
[Hematological changes associated with human immunodeficiency virus (HIV-1) infection]: Ugeskr Laeger. 1993 May 10;155(19):1442-6. Unique Identifier : AIDSLINE MED/93303783; Moller T; Hasselbalch HC; Epidemiafdeling M, Rigshospitalet, Kobenhavn.; Infection with human immunodeficiency virus type 1 (HIV-1) primarily involves a subgroup of T-lymphocytic cells, but other cell types are also invaded by the virus, including cell lines within the haematopoietic system. Together with infectious, inflammatory and neoplasic processes, invasion of haematopoietic tissue e
Evidence for the cooperation of gp120 amino acids 322 and 448 in SIVmac entry.: Virology. 1993 Jul;195(1):167-74. Unique Identifier : AIDSLINE MED/93303915; Morrison HG; Kirchhoff F; Desrosiers RC; Division of Microbiology, New England Regional Primate Research; Center, Harvard Medical School, Southborough, Massachusetts; 01772-9102.; The substitution of glycine for valine at amino acid 448 in the C4 domain of SIVmac239 envelope glycoprotein gp120 resulted in little or no viral infectivity for CEMX174 cells and rhesus monkey peripheral blood mononuclear cells. The block to viral replication was located at an early stage including virus entry into c
Molecular epidemiology of HIV-1 based on phylogenetic analysis of in vivo gag p7/p9 direct sequences.: Virology. 1993 Jul;195(1):185-94. Unique Identifier : AIDSLINE MED/93303917; Salminen M; Nykanen A; Brummer-Korvenkontio H; Kantanen ML; Liitsola K; Leinikki P; Department of HIV, National Public Health Institute, Helsinki,; Finland.; Viruses of different geographical origin are circulating in Finland . We wanted to test whether phylogenetic analysis of patient lymphocyte proviral quasispecies sequences could be used to group different strains into genetic lineage
Changes in the host range and growth potential of an HIV-1 clone are conferred by the vpu gene.: Virology. 1993 Jul;195(1):260-4. Unique Identifier : AIDSLINE MED/93303928; Du B; Wolf A; Lee S; Terwilliger E; Department of Medicine, New England Deaconess Hospital, Boston,; Massachusetts 02215.; vpu, alone among the genes of human immunodeficiency virus type 1 (HIV-1), is unique to this virus, with no analogous reading frame evident in the genomes of either HIV-2 or the related SIVs. Effects of vpu upon levels of virus production from infected cells have been noted, but vpu is dispensable for HIV-1 replicatio
Variation in HTLV-I sequences from rabbit cell lines with diverse in vivo effects.: Virology. 1993 Jul;195(1):271-4. Unique Identifier : AIDSLINE GENBANK/L03562; Zhao TM; Robinson MA; Sawasdikosol S; Simpson RM; Kindt TJ; Laboratory of Immunogenetics, NIAID Twinbrook II Facility,; Rockville, Maryland 20852.; Comparison of nucleotide sequences determined for HTLV-I integrated provirus from two rabbit cell lines, RH/K30 and RH/K34, revealed greater than 99% identity to one another. Substitutions encoding amino acid interchanges were observed in the gag, pol, and rex regions whereas the env and tax proteins were identical in
Factors that influence HIV/AIDS instruction in schools.: Adolescence. 1993 Summer;28(110):309-14. Unique Identifier : AIDSLINE MED/93304157; Denson DR; Voight R; Eisenman R; Department of Health and Physical Education, McNeese State; University, Lake Charles, Louisiana 70609.; Sex education is allowed but not required in Louisiana. It is taught at the discretion of local school districts as mandated in the Local Option Sex Education Statute, Act 480. HIV/AIDS education is also optional and may be taught without incorporating sex education policies. In the present study, a survey of ninety-e
Contraceptive health programs for adolescents: a critical review.: Adolescence. 1993 Summer;28(110):347-59. Unique Identifier : AIDSLINE MED/93304161; Lagana L; Hayes DM; Department of Psychology, Illinois Institute of Technology,; Chicago 60616.; Many adolescents are neither educated about contraception nor consistently practice it as part of their sexual health behavior. Contraceptive education has taken many forms and has been questioned as to its effectiveness. This paper reviews some of the contraceptive education programs that have been designed for adole
[HTLV-I and ocular disease]: Nippon Ganka Gakkai Zasshi. 1993 Apr;97(4):433-40. Unique Identifier : AIDSLINE MED/93304272; Ohba N; Nakao K; Department of Ophthalmology, Kagoshima University Faculty of; Medicine, Japan.; Human T-lymphotropic virus type 1 (HTLV-I) has an etiologic role in adult T-cell leukemia (ATL) and HTLV-I associated myelopathy (HAM). This paper reviews the ophthalmic literature relevant to the retrovirus. Patients with ATL may have intraocular invasion of proliferated T lymphocytes, lymphomatous lesion in the ocul
Diarrhea in Pneumocystis carinii pneumonia [letter]: Am J Gastroenterol. 1993 Jul;88(7):1138-9. Unique Identifier : AIDSLINE MED/93304347; Newton JA Jr; Weiss PJ; Litynski JJ
Elevated levels of heme oxygenase-1 activity and mRNA in peripheral blood adherent cells of acquired immunodeficiency syndrome patients.: Am J Hematol. 1993 May;43(1):19-23. Unique Identifier : AIDSLINE MED/93304380; Levere RD; Staudinger R; Loewy G; Kappas A; Shibahara S; Abraham NG; Department of Medicine, New York Medical College, Valhalla 10595.; Patients with the acquired immunodeficiency syndrome (AIDS) commonly develop hematological abnormalities, including anemia, leukopenia, and thrombocytopenia. Heme synthesis and heme degradation are critical to the maintenance of cellular heme homeostasis and to hematopoietic differentiation. We examined heme oxygenase
Reproductive health: a global perspective.: Am J Obstet Gynecol. 1993 Jun;168(6 Pt 1):1649-54. Unique Identifier : AIDSLINE MED/93304435; Sciarra JJ; Department of Obstetrics and Gynecology, Northwestern University; Medical School, Chicago, IL 60611.
Seventeen-year review of sexual and contraceptive behavior on a college campus.: Am J Obstet Gynecol. 1993 Jun;168(6 Pt 1):1833-7; discussion 1837-8. Unique Identifier : AIDSLINE MED/93304459; Hale RW; Char DF; Nagy K; Stockert N; Department of Obstetrics and Gynecology, John A. Burns School of; Medicine, University of Hawaii, Honolulu 96826.; OBJECTIVES: We reviewed current sexual and contraceptive behavior of college-age men and women and compared the findings with those of similar studies in 1974 and 1979. STUDY DESIGN: A randomly selected population questionnaire was provided to students registered in the spring 1991 semester. Of the 1921 survey forms m
Extravasation and transcytosis of liposomes in Kaposi's sarcoma-like dermal lesions of transgenic mice bearing the HIV tat gene.: Am J Pathol. 1993 Jul;143(1):10-4. Unique Identifier : AIDSLINE MED/93304476; Huang SK; Martin FJ; Jay G; Vogel J; Papahadjopoulos D; Friend DS; Cancer Research Institute, University of California, San; Francisco.; Transgenic mice bearing the HIV tat gene develop dermal lesions resembling a common malignant tumor in AIDS, Kaposi s sarcoma (KS). To evaluate the permeability characteristics of these lesions and the therapeutic potential of drug-carrying liposomes, we have studied the localization of sterically stabilized liposomes
In situ detection of PCR-amplified HIV-1 nucleic acids and tumor necrosis factor cDNA in cervical tissues.: Am J Pathol. 1993 Jul;143(1):40-8. Unique Identifier : AIDSLINE MED/93304502; Nuovo GJ; Forde A; MacConnell P; Fahrenwald R; Department of Pathology, SUNY, Stony Brook 11794-8691.; This study determined the histological distribution of polymerase chain reaction-amplified human immunodeficiency virus 1 (HIV-1) DNA and RNA in cervical tissues. Amplified HIV-1 DNA and complementary DNA were detected in each of 21 cervical biopsies from women with acquired immunodeficiency syndrome. The viral nuclei
[Clinical studies and treatment of Karposi's sarcoma of the head and neck in AIDS patients]: An Otorrinolaringol Ibero Am. 1993;20(3):267-77. Unique Identifier : AIDSLINE MED/93304598; Bujia J; Riederer A; Zietz C; Vogl T; Wilmes E; Catedra de Otorrinolaringologia,; Ludwig-Maximilians-Universitat Munchen.; Kaposi s sarcoma is the major neoplastic disease of HIV-infected patients in the head and neck regions. A clinical study realized at Ludwig-Maximilians University, Munchen, uncover 25 homosexuals with KS out of 135 HIB-positive patients. Six of them showed a KS as initial manifestation of the syndrome. The KS was foun
Pneumocystis carinii pleural effusion. Pathogenesis and pleural fluid analysis.: Am Rev Respir Dis. 1993 Jul;148(1):232-4. Unique Identifier : AIDSLINE MED/93304795; Horowitz ML; Schiff M; Samuels J; Russo R; Schnader J; Department of Medicine, North Shore University Hospital,; Manhasset, NY 11030.; We present three new cases of Pneumocystis carinii in pleural effusions of patients with AIDS, bringing the total number of reported cases to six. In our patients, diagnosis was made by visualization of Pneumocystis in pleural fluid stained with Gomori methenamine silver. LDH was greater than 400, and pleural fluid to
Management of spontaneous pneumothorax.: Am Rev Respir Dis. 1993 Jul;148(1):245-8. Unique Identifier : AIDSLINE MED/93304799; Light RW; Veterans Administration Medical Center, Long Beach, California; 90822.
Anti-HIV (human immunodeficiency virus) activity of sulfated paramylon.: Antiviral Res. 1993 May;21(1):1-14. Unique Identifier : AIDSLINE MED/93304934; Koizumi N; Sakagami H; Utsumi A; Fujinaga S; Takeda M; Asano K; Sugawara I; Ichikawa S; Kondo H; Mori S; et al; Department of Pathology, University of Tokyo, Japan.; Sulfated derivatives of paramylon, a water-insoluble (1-3)-beta-D-glucan from Euglena gracilis, significantly inhibited the cytopathic effect of human immunodeficiency virus (HIV-1, HIV-2) and the expression of HIV antigen in cultured MT-4, MOLT-4 cells and human peripheral blood mononuclear cells. Native paramylon, N
Characterization of two structurally novel HIV-1 protease inhibitors identified by rational selection.: Antiviral Res. 1993 May;21(1):73-84. Unique Identifier : AIDSLINE MED/93304939; Humblet CC; Lunney EA; Buckheit RW Jr; Doggett C; Wong R; Antonucci TK; Department of Chemistry, Parke-Davis Pharmaceutical Research; Division, Warner-Lambert Company, Ann Arbor, MI 48105.; The human immunodeficiency virus (HIV-1), associated with the AIDS (acquired immunodeficiency syndrome) epidemic, encodes an aspartyl protease that is essential for polyprotein processing in the virus (Navia et al., 1989). It has been demonstrated that inactivation of the protease either catalytically or by an inhibit
The risks of blood exposures.: AORN J. 1993 Jun;57(6):1329. Unique Identifier : AIDSLINE MED/93304942; Steelman VM
Abdominal mycobacterial infection mimicking acute appendicitis in an AIDS patient.: Aust N Z J Surg. 1993 Jul;63(7):558-60. Unique Identifier : AIDSLINE MED/93305029; Visvanathan K; Jones PD; Truskett P; Department of Infectious Diseases, Prince Henry Hospital, Sydney,; New South Wales, Australia.; A case of abdominal mycobacterial infection mimicking acute appendicitis in a human immunodeficiency virus (HIV) infected patient is reported. The case illustrates the unusual aetiology of an acute abdomen in this population and the report reviews the aetiology of surgical abdominal pain in HIV infection and discusses
Separation and partial characterization of proteinases with substrate specificity for basic amino acids from human MOLT-4 T lymphocytes: identification of those inhibited by variable-loop-V3 peptides of HIV-1 (human immunodeficiency virus-1) envelope glycoprotein.: Biochem J. 1993 Jun 15;292 ( Pt 3):711-8. Unique Identifier : AIDSLINE MED/93305053; Harvima IT; Harvima RJ; Nilsson G; Ivanoff L; Schwartz LB; Department of Internal Medicine, Medical College of Virginia,; Virginia Commonwealth University, Richmond 23298.; The V3 loop of the HIV (human immunodeficiency virus)-1 envelope glycoprotein gp120 likely plays a role in HIV-1 infectivity. Although the amino acid sequence of the V3 loop is hypervariable, it contains a conserved region, Gly-Pro-Gly-Arg, that shows similarity to the active-site Gly-Pro-Cys-Arg sequence of inter-alp
Subacute measles encephalitis in the young immunocompromised host: report of two cases diagnosed by polymerase chain reaction and treated with ribavirin and review of the literature.: Clin Infect Dis. 1993 May;16(5):654-60. Unique Identifier : AIDSLINE MED/93283552; Mustafa MM; Weitman SD; Winick NJ; Bellini WJ; Timmons CF; Siegel JD; Department of Pediatrics, University of Texas Southwestern; Medical Center, Dallas 75235-9063.; Two young patients with subacute measles encephalitis are described: a 20-year-old male hemophiliac infected with human immunodeficiency virus (HIV) and a 4-year-old girl with acute leukemia. Both patients were afebrile and had persistent focal seizures and slurred speech beginning 2 and 7 months, respectively, after
Isolation of Mycobacterium malmoense from HIV-positive patients [letter; comment]: J Infect. 1993 May;26(3):345-6. Unique Identifier : AIDSLINE MED/93280516; Willocks L; Leen CL; Brettle RP; Rayner A; Harris G; Watt B
Long-term observations of human immunodeficiency virus-infected chimpanzees [published erratum appears in AIDS Res Hum Retroviruses 1993 Jun;9(6):579]: AIDS Res Hum Retroviruses. 1993 Apr;9(4):375-8. Unique Identifier : AIDSLINE MED/93290933; Johnson BK; Stone GA; Godec MS; Asher DM; Gajdusek DC; Gibbs CJ Jr; Laboratory of Central Nervous System Studies, National Institute; of Neurological Disorders and Stroke, National Institutes of; Health, Bethesda, Maryland 20892.; Twenty-seven chimpanzees inoculated with material presumed to contain human immunodeficiency virus (HIV) between June 1983 and February 1985 were studied. The animals were examined on four to six occasions between 1989 and 1992 for serologic, virologic, hematologic, immunophenotypic, as well as clinical signs of HIV i
Catheter-associated sepsis due to Alcaligenes xylosoxidans in a child with AIDS [letter; comment] [see comments]: Clin Infect Dis. 1993 Apr;16(4):592-3. Unique Identifier : AIDSLINE MED/93291358; Cieslak TJ; Raszka WV
Antenatal HIV testing. Named testing is unevaluated and costly [letter; comment]: BMJ. 1993 May 29;306(6890):1479-80. Unique Identifier : AIDSLINE MED/93299258; Riley A
[Dementia in the elderly. Will we think in AIDS (letter)]: Aten Primaria. 1993 Apr;11(6):319. Unique Identifier : AIDSLINE MED/93271346; Vila i Coll MA; Cuencia i Olivas AM; Fuentes Perez MA; Pou i Vila MR
Atypical autoantigen targets of perinuclear antineutrophil cytoplasm antibodies (P-ANCA): specificity and clinical associations.: J Autoimmun. 1993 Apr;6(2):185-95. Unique Identifier : AIDSLINE MED/93270648; Lesavre P; Noel LH; Gayno S; Nusbaum P; Reumaux D; Erlinger S; Grunfeld JP; Halbwachs-Mecarelli L; Department of Nephrology, Hopital Necker, Paris, France.; Atypical antineutrophil cytoplasm antibodies (A-ANCA) are defined here as ANCA detected by IIF and not directed against the predominant ANCA antigens, proteinase 3 (PR3) and myeloperoxidase (MPO). A-ANCA are found in a variety of clinical conditions, namely rheumatoid arthritis, inflammatory bowel diseases, chronic he
Cell-mediated immunity to BLV replication: analogous to HIV immunopathogenesis? [letter; comment]: Immunol Today. 1993 Apr;14(4):190-1. Unique Identifier : AIDSLINE MED/93270680; Sugimoto M; Ohishi K; Ikawa Y
Foscarnet treatment in various cytomegalovirus infections.: Int J Clin Pharmacol Ther Toxicol. 1993 Apr;31(4):204-7. Unique Identifier : AIDSLINE MED/93273544; Brockmeyer NH; Hengge UR; Mertins L; Malessa R; Steinmetz R; Gooss M; Department of Dermatology, University of Essen, Germany.; We examined the effect of foscarnet (Foscavir) in 15 AIDS patients with cytomegalovirus infection. Cytomegalovirus infection was presented as retinits (n = 8), colitis (n = 3), oral (n = 1) and perianal ulcers (n = 3) and pneumonitis (n = 1). Induction therapy with foscarnet showed
T-cell lymphoma associated with periodontal disease and HIV infection. A case report.: J Clin Periodontol. 1993 May;20(5):378-80. Unique Identifier : AIDSLINE MED/93274003; Palmer GD; Morgan PR; Challacombe SJ; Department of Oral Medicine and Pathology, United Medical School,; Guy's Hospital, London, UK.; A case is described of gingival non-Hodgkins lymphoma presenting in a site previously diagnosed as HIV-periodontitis. The lymphoma presented along with other signs of HIV infection and AIDS, which taken together were compatible with increased immunosuppression and reactivation of Epstein-Barr virus. The implications o
Depressed neutrophil superoxide production in human immunodeficiency virus infection.: J Infect Dis. 1993 Jun;167(6):1406-10. Unique Identifier : AIDSLINE MED/93274101; Pitrak DL; Bak PM; DeMarais P; Novak RM; Andersen BR; Department of Medicine, University of Illinois College of; Medicine, Chicago.; Neutrophil (PMNL) superoxide (O2-) production was evaluated in 71 patients with human immunodeficiency virus (HIV) infection at different stages of disease. In vitro O2- production was significantly depressed for PMNL isolated from HIV-positive patients compared with control PMNL at rest and after stimulation. The deg
Feline immunodeficiency virus infection. Clinicopathologic findings in 90 naturally occurring cases.: J Vet Intern Med. 1993 Mar-Apr;7(2):85-90. Unique Identifier : AIDSLINE MED/93274612; Sparkes AH; Hopper CD; Millard WG; Gruffydd-Jones TJ; Harbour DA; Department of Veterinary Medicine, University of Bristol,; Langford, United Kingdom.; In 90 cats with naturally occurring feline immunodeficiency virus (FIV) infection, the clinicopathologic changes seen at the time of first diagnosis of FIV infection included lymphopenia (29%), neutrophilia (27%), monocytosis (23%), anemia (18%), leukocytosis (13%), leukopenia (13%), neutropenia (11%), hyperproteinemi
Effect of feline immunodeficiency virus infection on Toxoplasma gondii-specific humoral and cell-mediated immune responses of cats with serologic evidence of toxoplasmosis.: J Vet Intern Med. 1993 Mar-Apr;7(2):95-100. Unique Identifier : AIDSLINE MED/93274614; Lappin MR; Marks A; Greene CE; Rose BJ; Gasper PW; Powell CC; Reif JS; Department of Clinical Sciences, College of Veterinary Medicine; and Biomedical Sciences, Colorado State University, Fort Collins; 80523.; Serum samples from 89 cats with serologic evidence of toxoplasmosis were identified by using an enzyme-linked immunosorbent assay (ELISA) that detected Toxoplasma gondii-specific immunoglobulin M (IgM) or T. gondii-specific immunoglobulin G (IgG). Concurrent feline immunodeficiency virus (FIV) infection was detected i
Mutagenesis of EIAV TAT reveals structural features essential for transcriptional activation and TAR element recognition.: Virology. 1993 Jun;194(2):530-6. Unique Identifier : AIDSLINE MED/93276539; Derse D; Newbold SH; Laboratory of Viral Carcinogenesis, NCI-Frederick Cancer Research; and Development Center, Maryland 21702-1201.; Certain members of the lentivirus subfamily of retroviruses encode unique transcriptional activator (Tat) proteins that modify the transcription complex after binding to the 5 end of nascent viral mRNA. The Tat proteins are modular, containing RNA-binding and activation domains that can be exchanged between different
Analysis of the rhesus cytomegalovirus immediate-early gene promoter.: Virology. 1993 Jun;194(2):815-21. Unique Identifier : AIDSLINE MED/93276571; Alcendor DJ; Barry PA; Pratt-Lowe E; Luciw PA; Department of Medical Pathology, University of California, Davis; 95616.; A cytomegalovirus ( CMV ) isolate has been recovered from a rhesus macaque (Macaca mulatta) experimentally infected with simian immunodeficiency virus. The full-length immediate-early gene (IE) was cloned from a genomic library
Herpesvirus saimiri transformed human T cell lines: a permissive system for human immunodeficiency viruses.: Virology. 1993 Jun;194(2):875-7. Unique Identifier : AIDSLINE MED/93276582; Nick S; Fickenscher H; Biesinger B; Born G; Jahn G; Fleckenstein B; Institut fur Klinische und Molekulare Virologie, Universitat; Erlangen-Nurnberg, Germany.; Human peripheral blood T lymphocytes are readily transformed to continuous growth by Herpesvirus saimiri subgroup C strains. The immortalized cells express the phenotype of mature activated T cells and bear either CD4 or CD8 surface markers. Here we report that Herpesvirus saimiri transformed CD4+ cell lines are highl
Feline CD4 molecules expressed on feline non-lymphoid cell lines are not enough for productive infection of highly lymphotropic feline immunodeficiency virus isolates.: Arch Virol. 1993;130(1-2):171-8. Unique Identifier : AIDSLINE MED/93277376; Norimine J; Miyazawa T; Kawaguchi Y; Tomonaga K; Shin YS; Toyosaki T; Kohmoto M; Niikura M; Tohya Y; Mikami T; Department of Veterinary Microbiology, Faculty of Agriculture,; University of Tokyo, Japan.; To investigate whether the feline CD 4 (fCD4) molecules are involved in infections of highly lymphotropic feline immunodeficiency virus (FIV) isolates, we expressed fCD4 stably on Crandell feline kidney cells and Felis catus whole foetus 4 cells by transfection of a cDNA encoding the fCD4 glycoprotein, and then infect
Characterization of the hepatitis B virus transactivators: a possible direct role of the virus in the development of hepatocellular carcinoma.: J Surg Oncol Suppl. 1993;3:34-6. Unique Identifier : AIDSLINE MED/93277659; Levrero M; Balsano C; Avantaggiati ML; Natoli G; Chirillo P; De Marzio E; Collepardo D; Costanzo A; Istituto di I Clinica Medica e Fondazione Andrea Cesalpino,; Universita degli Studi di Roma La Sapienza, Italy.
The foamy virus family: molecular biology, epidemiology and neuropathology.: Biochim Biophys Acta. 1993 May 25;1155(1):1-24. Unique Identifier : AIDSLINE MED/93277904; Aguzzi A; Institute of Neuropathology, Department of Pathology, University; of Zurich.; The family of foamy viruses designates a group of retroviruses which share a specific morphology and provoke characteristic cytopathic effects in cultured cells. Like HTLV and HIV, foamy viruses are complex viruses encoding a number of ancillary genes in addition to gag, pol and env, including a transcriptional transa
[Disseminated toxoplasmosis in AIDS]: Dtsch Med Wochenschr. 1993 Jun 4;118(22):814-9. Unique Identifier : AIDSLINE MED/93279174; Holch A; Opravil M; Moradpour D; Siegenthaler W; Schneider J; Luthy R; Abteilung Infektiologie, Universitatsspital, Zurich.; Within one year a 46-year-old HIV-positive man developed Pneumocystis carinii pneumonia, candida oesophagitis and recurrent mucocutaneous herpes simplex infections. He finally developed a constant fever without any infection-localizing features. There was pancytopenia, increased activities of the transaminases, lactat
Is human papillomavirus-related disease an independent risk factor for human immunodeficiency virus infection?: Gynecol Oncol. 1993 May;49(2):243-6. Unique Identifier : AIDSLINE MED/93279576; Spitzer M; Brennessel D; Seltzer VL; Silver L; Lox MS; Department of Obstetrics and Gynecology, Queens Hospital Center,; Jamaica, NY 11432.; We sought to determine the prevalence of human immunodeficiency virus (HIV) infection in a population of women with human papillomavirus (HPV)-related diseases attending a colposcopy clinic who had no other CDC-defined risk factors for HIV. Study patients included all new patients attending our colposcopy clinic who w
Comparison of the substrate-binding pockets of the Rous sarcoma virus and human immunodeficiency virus type 1 proteases.: J Biol Chem. 1993 Jun 5;268(16):11711-20. Unique Identifier : AIDSLINE MED/93280130; Cameron CE; Grinde B; Jacques P; Jentoft J; Leis J; Wlodawer A; Weber IT; Case Western Reserve University School of Medicine, Cleveland,; Ohio 44106-4935.; A steady state kinetic analysis of the avian myeloblastosis virus/Rous sarcoma virus (AMV/RSV) and human immunodeficiency virus Type 1 (HIV-1) retroviral proteases (PRs) was carried out using a series of 40 peptide substrates that are derivatives of the AMV/RSV nucleocapsid-PR cleavage site. These peptides contain sin
Viral infections in the dental setting: potential effects on pregnant HCWs.: J Am Dent Assoc. 1993 Jun;124(6):79-86. Unique Identifier : AIDSLINE MED/93280373; Glick M; Goldman HS; Department of Oral Medicine, Temple University School of; Dentistry, Philadelphia, Pa. 19140.; Occupational exposure of pregnant health care workers to infectious diseases may cause a variety of effects. This article reviews potential effects of viral infections in pregnant health care workers by pathogens transmittable in a dental setting.
Neurological disease induced in transgenic mice expressing the env gene of the Cas-Br-E murine retrovirus.: Proc Natl Acad Sci U S A. 1993 May 15;90(10):4538-42. Unique Identifier : AIDSLINE MED/93281614; Kay DG; Gravel C; Pothier F; Laperriere A; Robitaille Y; Jolicoeur P; Laboratory of Molecular Biology, Clinical Research Institute of; Montreal, Quebec, Canada.; The Cas-Br-E murine leukemia virus induces a spongiform myeloencephalopathy in susceptible mice. We constructed transgenic mice harboring either the viral genome (in a replication-defective form) or only its env gene. Low levels of expression of either transgene resulted in mild neuropathology and/or signs of neurolog
Lipid composition and fluidity of the human immunodeficiency virus envelope and host cell plasma membranes.: Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5181-5. Unique Identifier : AIDSLINE MED/93281721; Aloia RC; Tian H; Jensen FC; Anesthesia Service, J. L. Pettis Veterans Administration; Hospital, Loma Linda, CA 92357.; Previous studies have indicated that human immunodeficiency virus (HIV) is enclosed with a lipid envelope similar in composition to cell plasma membranes and to other viruses. Further, the fluidity, as measured by spin resonance spectroscopy, is low and the viral envelope is among the most highly ordered membranes ana
Light-mediated activities of thiarubrines against human immunodeficiency virus.: Photochem Photobiol. 1993 Apr;57(4):675-80. Unique Identifier : AIDSLINE MED/93281773; Hudson JB; Balza F; Harris L; Towers GH; Division of Medical Microbiology, University of British Columbia,; Vancouver, Canada.; Two thiarubrines (dithiacyclohexadienes), which were isolated recently from species of Asteraceae, were investigated for light-mediated antiviral activity against human immunodeficiency virus (HIV-1). Both compounds (thiarubrines A and D) showed good anti-HIV activity, in micromolar concentrations, which was dependent
Transscleral iontophoresis of foscarnet.: Am J Ophthalmol. 1993 Jun 15;115(6):748-54. Unique Identifier : AIDSLINE MED/93282462; Sarraf D; Equi RA; Holland GN; Yoshizumi MO; Lee DA; Jules Stein Eye Institute, Department of Ophthalmology,; University of California, Los Angeles.; Current local treatments of cytomegalovirus retinopathy may result in serious intraocular complications. Using an animal model, we investigated transscleral iontophoresis as a technique for delivery of foscarnet to the vitreous. Using a probe tip surface area of 0.19 mm2, a current
Primary and secondary erythema migrans in central Wisconsin.: Arch Dermatol. 1993 Jun;129(6):709-16. Unique Identifier : AIDSLINE MED/93282669; Melski JW; Reed KD; Mitchell PD; Barth GD; Department of Dermatology, Marshfield Clinic, WI 54449.; BACKGROUND AND DESIGN--We report a series of 28 consecutive patients with erythema migrans (EM) who underwent skin biopsies for culture of Borrelia burgdorferi. Culture results, Lyme serologic findings, and clinical features in patients with only primary EM are compared with those in patients with secondary EM. RESULT
Effect of topoisomerase inhibitors on the in vitro HIV DNA integration reaction.: Biochem Biophys Res Commun. 1993 May 14;192(3):1409-14. Unique Identifier : AIDSLINE MED/93282853; Carteau S; Mouscadet JF; Goulaouic H; Subra F; Auclair C; Laboratoire de Pharmacologie des Macomolecules Biologiques, CNRS; URA 0147, INSERM U 140, Institut Gustave Roussy, Villejuif,; France.; Retroviral growth requires as an obligatory step the integration of a DNA copy of the viral RNA into the genomic DNA of the host. Recombinant human immunodeficiency virus type I (HIV-1) integrase (IN) expressed in Escherichia coli efficiently catalyzes the overall in vitro integration reaction, namely, the processing
Immunological parameters during treatment with ditiocarb (Imuthiol).: AIDS. 1993 Apr;7(4):525-30. Unique Identifier : AIDSLINE MED/93283063; Vanham GL; Kestens L; Van Hoof J; Penne G; Colebunders R; Goilav C; Vandenbruaene M; el Habib R; Gigase P; Institute of Tropical Medicine, Antwerp, Belgium.; OBJECTIVES: To examine the effect of ditiocarb (DTC) treatment on immunological parameters of HIV infection. Immunophenotyping included CD4+ T-cell counting and the analysis of activation markers on CD8+ T cells. Anti-CD3-induced proliferation and anti-CD3-mediated cytotoxicity were monitored as indexes of T-cell func
The surveillance definition for AIDS in the United States [editorial]: AIDS. 1993 Apr;7(4):585-7. Unique Identifier : AIDSLINE MED/93283071; Buehler JW; Ward JW; Berkelman RL
Statistics from the Centers for Disease Control and Prevention.: AIDS. 1993 Apr;7(4):601-3. Unique Identifier : AIDSLINE MED/93283081
Epstein-Barr virus-related oral T-cell lymphoma associated with human immunodeficiency virus immunosuppression.: Blood. 1993 Jun 15;81(12):3350-6. Unique Identifier : AIDSLINE MED/93283686; Thomas JA; Cotter F; Hanby AM; Long LQ; Morgan PR; Bramble B; Bailey BM; Department of Clinical Sciences, London School of Hygiene and; Tropical Medicine, UK.; Epstein-Barr virus (EBV) is generally held to infect B cells and epithelial cells, although there are now reports of EBV infection in normal T cells and neoplastic T-cell diseases. In patients with human immunodeficiency virus (HIV) infection, EBV is associated with the benign epithelial lesion, hairy leukoplakia, and
Excitatory amino acid receptors, excitotoxicity, and the human nervous system.: Curr Opin Neurol Neurosurg. 1993 Jun;6(3):414-22. Unique Identifier : AIDSLINE MED/93283767; Shaw PJ; Department of Neurology, Royal Victoria Infirmary, Newcastle upon; Tyne, UK.; Glutamate receptors continued to be the subject of intense investigation during 1992. It is clear that there is great structural and functional diversity within this receptor family, although the precise subunit structure of excitatory amino acid (EAA) receptors in specific neuronal groups within the human central ner</