1993

AIDS-the untold story (Gene Antonio). [sound recording].: Arcadia, CA : Focus on the Family, p1986 1 sound cassette : analog Unique Identifier : AIDSLINE AV/9300411A; Antonio G
The:Last laugh. [videorecording]: Boston, MA : Fanlight Productions, c1990 1 videocassette (56 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9300399A; Kellerman S; (Producer) Celebrating the healing power of laughter, hope, and positive thinking, this program documents a three-day comedy workshop for People with AIDS (PWA s). Nine men who had never set foot on stage before learn the tricks of the trade from professional comics and present their act in a sold-out show. For the
Bloodborne pathogens standard for nurses. [videorecording]: [Tucson, Ariz.] : Medfilms, c1992 1 videocassette (9 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9300381A; Reeter AK
HIV infection : ethics in practice. [videorecording]: [Oakland, Calif.?] : Kaiser Foundation Health Plan, c1992 1 videocassette (50 min.) : sd., col. ; 1/2 in (Medicine in the nineties) Unique Identifier : AIDSLINE AV/9300398A; Wolfe E
[El:SIDA y otras enfermedades.]: Barcelona : Ediciones Aura, c1986 189 p Unique Identifier : AIDSLINE CAT/9305014; Sales DJ
[AIDS : Herausforderung an paritatische Sozialarbeit.]: Hannover : Deutscher Paritatischer Wohlfahrtsverband, Landesverband Niedersachsen, Der Vorstand, [1987] 9, 7 leaves (DPWV-Dokumente) Unique Identifier : AIDSLINE CAT/9304658; Neubelt W
AIDS : the role of the employer in prevention.: Johannesburg : Issued and distributed by the National Council for Mental Health, [1988] 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9304141
AIDS--a perspective for Canadians : background papers.: Ottawa, Ont., Canada : The Society, c1988 x, 407 p. : ill Unique Identifier : AIDSLINE CAT/9304142
Blaming others : prejudice, race, and worldwide AIDS.: Washington : Panos Institute ; Philadelphia, PA : New Society Publishers, c1988 vii, 168 p. : ill Unique Identifier : AIDSLINE CAT/9304162; Sabatier R; Tinker J
A:synopsis of state AIDS laws enacted during the 1983-1987 state legislative sessions.: Washington, D.C. : Intergovernmental Health Policy Project, State AIDS Policy Center, George Washington University, [1988] 124, 8 p Unique Identifier : AIDSLINE CAT/9304624; Thomas C
[AIDS und Psychiatrie : Tagungsruckblick : Donnerstag, 10. November 1988 im Volkshaus (Theatersaal) Zurich.]: Weinfelden : Pro Mente Sana, [1989?] 65 p. : ill Unique Identifier : AIDSLINE CAT/9304654
Workbook for the Fifth National Pediatric AIDS Conference and the follow-up to the 1987 Surgeon General's Workshop on Children with HIV Infection and their Families.: [Rockville, Md. : Pediatric AIDS Program, Office of Maternal and Child Health, Health Resources and Services Administration, Dept. of Health and Human Services ; Washington, D.C. : Distributed by the National Maternal and Child Health Clearinghousec1989], 1989] 1 v. (loose-leaf) Unique Identifier : AIDSLINE CAT/9305837; Hutchings JJ; Cronin MA; Their Families
Care of the HIV-infected patient : a dental perspective.: Boston, MA (131 Clarendon St., Boston 02116) : AIDS Action Committee of Massachusetts, c1990 21 p., [1] folded leaf of plates Unique Identifier : AIDSLINE CAT/9304168; Husack WA; Zide-Selbovitz L
HIV seroprevalence report.: Portland, OR : The Program, v Unique Identifier : AIDSLINE CAT/9304326
Projections of acquired immune deficiency syndrome in Australia using data to the end of September 1989.: Canberra : National Centre for Epidemiology and Population Health, the Australian National University, [1990] ii, 138 p. : ill (Working papers / National Centre for Epidemiology and Population Health, ISSN 1033-1557 ; no. 16) Unique Identifier : AIDSLINE CAT/9304476; Solomon PJ; Fazekas de St. Groth C; Wilson SR
[SPID--mozhno li ostanovit' epidemiiu? : o sotrudnichestve stran-chlenov SEV v oblasti bor'by so SPIDom.] Izd. 2-e, dop.: Moskva : Sovet ekon. vzaimopomoshchi, Sekretariat, 1990 45 p. : ill Unique Identifier : AIDSLINE CAT/9304543; Pokrovskii VA
A:summary of AIDS laws from the 1989 legislative session.: Washington, D.C. : AIDS Policy Center, Intergovernmental Health Policy Project, George Washington University, [1990] xv, 176 p. : ill Unique Identifier : AIDSLINE CAT/9304622; Bowleg IA
The:trialing, approval, and marketing of treatments & therapies for HIV/AIDS and related illnesses in Australia : a policy document. 1st ed.: [Darlinghurst, NSW] : AIDS Council of New South Wales, [1990] 100 p Unique Identifier : AIDSLINE CAT/9304626
AIDS : an issue for every woman : an edited report of the proceedings of a Women and AIDS Support Network Conference, held in Harare, Zimbabwe on the 23rd and 24th November 1989 : report.: Harare, Zimbabwe : Women and AIDS Support Network, 1990 42 p. : ill Unique Identifier : AIDSLINE CAT/9304655; Willmore B; Ray S
[AIDS.] 1. Aufl.: Berlin : Verlag Gesundheit, c1990 90 p. : ill Unique Identifier : AIDSLINE CAT/9304656; Sonnichsen N
Pediatric AIDS and hospital care in the U.S. : report on the 1987 U.S. hospital pediatric AIDS survey.: Washington, D.C. : National Public Health and Hospital Institute, [1990] 15 p. : ill Unique Identifier : AIDSLINE CAT/9304920; Andrulis DP
The:AIDS notebooks.: Albany : State University of New York Press, c1990 xii, 166 p (SUNY series in the philosophy of the social sciences) Unique Identifier : AIDSLINE CAT/9305102; Schecter S
The:HIV risk-taking behaviour scale (HRBS) manual.: [Kensington, N.S.W.] : National Drug and Research Centre, 1990 8 leaves (Technical report ; no. 10) Unique Identifier : AIDSLINE CAT/9305218; Ward J; Darke S; Hall W
HIV/AIDS statistics. Mar. 1990-Sept. 1992.: Jefferson City, MO : Missouri Dept. of Health, Bureau of AIDS Prevention, [1990-1992] v. : ill Unique Identifier : AIDSLINE CAT/9305219
The:caregivers' journey : when you love someone with AIDS.: [City Center, Minn.] : Hazelden, 1990 x, 237 p Unique Identifier : AIDSLINE CAT/9305456; Pohl M; Kay D; Toft D
Patients with human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS).: Affairs Chicago, Ill. (211 E. Chicago Ave., Chicago 60611) : American Dental Association, Council on Community Health, Hospital, Institutional, and Medical Affairs, [1990] 12 p (Oral health care guidelines) Unique Identifier : AIDSLINE CAT/9305707
[AIDS-Aufklarung : medizinische und ethische Aspekte.]: Frankfurt Am Main ; New York : Peter Lang, c1991 137 p Unique Identifier : AIDSLINE CAT/9304143; Eiff AW
[Le:SIDA : guide du praticien : diagnostic, prise en charge, traitement.]: Geneve : Editions Medecine & hygiene, c1991 120 p. : ill Unique Identifier : AIDSLINE CAT/9304542; Hirschel B
[El:SIDA en Puerto Rico : acercamientos multidisciplinarios.] 1. ed.: Rio Piedras, PR : Universidad de Puerto Rico, 1991 ix, 314 p. : ill Unique Identifier : AIDSLINE CAT/9305013; Cunningham I
The:twin epidemics of substance use and HIV : report.: Syndrome Washington, D.C. (1730 K St. NW, suite 815, Washington 20006) : The Commission, [1991] 19 p. : ill Unique Identifier : AIDSLINE CAT/9305088
AIDS and life insurance.: London : Dept. of Health : HMSO, 1991 iii, 37 p Unique Identifier : AIDSLINE CAT/9305101
AIDS, an epidemic of ethical puzzles.: Aldershot, Hants [England] ; Brookfield, Vt., USA : Dartmouth, c1991 xi, 187 p Unique Identifier : AIDSLINE CAT/9305103
HIV disease in correctional facilities : report.: Syndrome Washington, D.C. (1730 K St., NW, Suite 815, Washington 20006) : The Commission, [1991] 43 p Unique Identifier : AIDSLINE CAT/9305217
Pediatric AIDS : abstracts of active projects, FY 1990 and FY 1991.: Washington, D.C. (38th and R St., NW, Washington 20057) : National Center for Education in Maternal and Child Health : [Distributed by] National Maternal and Child Health Clearinghouse, [1991] v, 70 p Unique Identifier : AIDSLINE CAT/9305708
Report : Regional Workshop for Programme Managers of National AIDS Committees, convened by the Regional Office for the Western Pacific of the World Health Organization, Canberra, Australia, 3-4 August 1990.: Pacific Committees Manila, Philippines : The Office, [1991] 26 p Unique Identifier : AIDSLINE CAT/9305747
Report.: Western Pacific Region Manila, Philippines : Printed and distributed by the Regional Office for the Western Pacific of the World Health Organization, [1992] 29 p. : ill (Report series ; no. RS/91/GE/31(PHL)) Unique Identifier : AIDSLINE CAT/9304499
Report.: among Commercial Sex Workers Manila, Philippines : Printed and distributed by the Regional Office for the Western Pacific of the World Health Organization, [1992] 28 p (Report series ; no. RS/91/GE/33(PHL)) Unique Identifier : AIDSLINE CAT/9304500
AIDS : women, drugs, and social care.: London ; Washington, DC : Falmer Press, 1992 x, 135 p (Social aspects of AIDS ; v. 1) Unique Identifier : AIDSLINE CAT/9304657; Dorn N; Henderson S; South N
Clinical assessment and treatment of HIV : rehabilitation of a chronic illness.: Thorofare, NJ : SLACK, c1992 xx, 260 p. : ill Unique Identifier : AIDSLINE CAT/9304696; Galantino ML
Report.: Control Programmes Manila, Philippines : Printed and distributed by the Regional Office for the Western Pacific of the World Health Organization, [1992] 24 p (Report series ; no. RS/91/GE/15(SMA)) Unique Identifier : AIDSLINE CAT/9304971
Let's talk : an honest conversation on critical issues : abortion, euthanasia, AIDS, health care.: Grand Rapids, Mich. : Zondervan, c1992 138 p Unique Identifier : AIDSLINE CAT/9305263; Koop CE; Johnson GT
AIDS : lessons from the first decade.: Dubuque, Iowa : Kendall/Hunt Pub. Co., c1992 v, 169 p. : ill Unique Identifier : AIDSLINE CAT/9305505; Appleman MM; DellaCorte C
HIV connect.: New York, NY : Library for AIDS/HIV Resources, New York City Dept. of Health, v Unique Identifier : AIDSLINE CAT/9305632
HIV infection : a clinical manual. 2nd ed.: Boston : Little, Brown, c1993 xviii, 555 p., [4] p. of plates : ill Unique Identifier : AIDSLINE CAT/9304815; Libman H; Witzburg RA
HIV infection in women.: Edinburgh ; New York : Churchill Livingstone, 1993 x, 290 p. : ill Unique Identifier : AIDSLINE CAT/9305633; Johnson MA; Johnstone FD
Erythropoietin: molecular, cellular, and clinical biology.: The Johns Hopkins Series in Contemporary Medicine and Public Health. Erslev AJ et al, eds. Baltimore, MD, Johns Hopkins University Press, 478 p., 1991. Unique Identifier : AIDSLINE ICDB/93688707; Anonymous; No affiliation given; Early studies showed that the action of erythropoietin is directed at primitive, still undifferentiated cells. Subsequent studies outlined the hierarchy of red cell development from multipotential stem cells via erythroid-committed progenitor cells and erythroid precursor cells to mature red cells and showed that eryt
Erythropoietin: physiology and clinical applications.: Blood Cell Growth Factors: Their Present and Future Use in Hematology and Oncology. Murphy MJ Jr, ed. Dayton, OH, AlphaMed Press, p. 105-20, 1991.. Unique Identifier : AIDSLINE ICDB/93689909; Spivak JL; Dept. of Medicine, Johns Hopkins Univ. Sch. of Medicine,; Baltimore, MD; Recombinant human erythropoietin (rhEpo) has come of age. Clinical trials have substantiated that the hormone can alleviate transfusion requirements, correct anemia and improve the quality of life in patients (pts) with end-stage renal disease. Epo is also effective in correcting anemia in pts with rheumatoid arthriti
Current concepts in psycho-oncology IV. October 10-12, 1991. New York, NY.: Current Concepts in Psycho-oncology IV. October 10-12, 1991. New York, NY, 331 p., 1991.. Unique Identifier : AIDSLINE ICDB/93690048; Anonymous; No affiliation given; This volume is the syllabus of a postgraduate course presented October 10-12, 1991, at Memorial Sloan-Kettering Cancer Center, New York. It includes full-length papers, workshop papers, and abstracts of poster presentations. The full-length papers include cancer in the socioeconomically disadvantaged (the role of inte
Clinical use of antibodies: tumors, infection, infarction, rejection, and in the diagnosis of aids.: Dev Nuclear Med; 19:1-185 1991. Unique Identifier : AIDSLINE ICDB/93690049; Anonymous; No affiliation given; In the past decade, since the first use of radiolabeled monoclonal antibodies (MAbs) in man, tremendous progress has occurred in the field of immunoscintigraphy. A large panel of highly specific MAbs against tumor-associated antigens as well as normal cell compounds has been developed. Enormous progress has been made
Malignant lymphoma: biology, natural history, and treatment.: Malignant Lymphoma: Biology, Natural History, and Treatment. Malvern, PA, Lea and Febiger, 395 p., 1991.. Unique Identifier : AIDSLINE ICDB/93690052; Aisenberg AC; Harvard Medical Sch., Boston, MA; This book approaches lymphoma as a subject for scientific inquiry, yet treatment is always in mind. The author cites a 40-yr interest in his subject, but claims to have learned more in the 18 mo before publication than during the preceding decades. These latest data are reviewed: (1) Hodgkin s disease (epidemiology, i
Quality of life: psychological, family, and social correlates in children with hemophilia.: Diss Abstr Int [B]; 52(9):4672 1992. Unique Identifier : AIDSLINE ICDB/93682321; Tse AM; Univ. of Illinois at Chicago, Health Sciences Center; Nursing management programs for children with hemophilia successfully reduced the incidence of deformities and immobilization, resulting in a near normal quality of life for children affected by this problem. Children with hemophilia who received transfusions or coagulation factors between 1979 and 1985 were exposed t
Chemoprevention by dietary dehydroepiandrosterone (DHEA): inhibition of lymphopoiesis.: Diss Abstr Int [B]; 52(9):4660 1992. Unique Identifier : AIDSLINE ICDB/93682331; Risdon GH; Univ. of Texas Health Science Center at Dallas; DHEA, a C-19 steroid, is one of the major secretory products of the human adrenal gland. Low levels of DHEA-sulfate have been correlated with both the risk and presence of breast cancer in women and cardiovascular disease in men. In rodents, the ingestion of DHEA inhibits the development of neoplasia, diabetes, obesit
Roles of retroviral R regions in long terminal repeat-driven gene expression.: Diss Abstr Int [B]; 53(4):1708 1992. Unique Identifier : AIDSLINE ICDB/93688343; Cupelli LA; Yeshiva Univ.; The R region of the retroviral long-terminal repeat (LTR) marks the site of transcription initiation of provirus RNAs and has been well characterized for its role in viral replication. In the human retroviruses, the R region also functions in the expression of viral genomes. A sequence within the R region of the human
Development and application of an assay for 2',5'-oligoadenylate synthetase activity in human cells.: Diss Abstr Int [B]; 53(5):2261 1992. Unique Identifier : AIDSLINE ICDB/93688580; Miele ME; Pennsylvania State Univ.; 2,5A synthetase catalyzes the polymerization of ATP into 2 ,5 -linked oligoadenylates of varying chain lengths (2,5A). To identify these multiple oligoadenylates, a method was devised utilizing electrophoretic separation of 32P-labeled 2,5A in a thin 20% polyacrylamide gel containing 7 M urea. A mixture of 2,5A synthe
CT of mesenteric and peritoneal lymphoma (Meeting abstract).: American Roentgen Ray Society Ninety-second Annual Meeting. May 10-15, 1992, Orlando, FL, p. 53-4, 1992.. Unique Identifier : AIDSLINE ICDB/93688906; Crawley G; Baker ME; Gulliver D; Leder R; Paulson E; Roubidoux M; Dunnick NR; Durham, NC; Our purpose was to determine the incidence and pattern of mesenteric and peritoneal, non-Hodgkin s lymphoma (NHL) on CT and to determine if unusual manifestations are isolated or found in conjunction with extensive disease and if these are caused by AIDS. Methods: Over a 4-yr perio
Identification and characterization of the early antigen complex of HHV-6.: Diss Abstr Int [B]; 53(7):3312 1993. Unique Identifier : AIDSLINE ICDB/93690163; Iyengar S; Georgetown Univ. Medical Center; HHV-6, a new herpes virus described in 1986, is a causative agent of exanthem subitum. Sero-epidemiological and biological studies have implicated this virus in various lymphoproliferative diseases, AIDS and cancer. The etiological significance of these disease associations is unclear. In order to investigate the role
Malignant lymphomas.: Hematology; 14:299-334 1991. Unique Identifier : AIDSLINE ICDB/93689059; Cabanillas F; UT M.D. Anderson Cancer Center, Houston, TX 77030; The malignant lymphomas are a group of heterogeneous disorders that cover a wide range of clinical behaviors. Two fundamental requirements for the management of lymphomas are (1) appropriate pathological classification and (2) good understanding of the natural history of the various cell types. Characteristics and man
The envelope proteins of HTLV-1: analysis of variability and function (Meeting abstract).: Br J Cancer; 65(Suppl 16):2 1992. Unique Identifier : AIDSLINE ICDB/93689951; Schulz TF; Carrington CV; Clapham P; Weiss RA; Chester Beatty Laboratories, Inst. of Cancer Res., London, UK; HTLV-I, the causative agent of adult T-cell leukemia and tropical spastic paraparesis, is a highly conserved human retrovirus endemic to southern Japan , the Caribbean, Africa and South America. In vivo the virus is mainly found in CD4+ T cells, and its envelope protein is thought to
A phase I/II study of recombinant tumor necrosis factor and recombinant interferon gamma in patients with AIDS-related complex.: Biotechnol Ther. 1989-90;1(3):229-36. Unique Identifier : AIDSLINE MED/93160946; Kaplan LD; Abrams DI; Sherwin SA; Kahn J; Volberding PA; Department of Medicine, San Francisco General Hospital,; California 94110.; A clinical trial was conducted to determine the tolerance and toxicity of recombinant tumor necrosis factor (rTNF) and recombinant interferon gamma (rIFN-gamma) when administered concurrently by continuous intravenous infusion to 11 patients with the AIDS-related complex (ARC). In addition, HIV culture, p24 antigen le
Hairy leukoplakia: diagnosis and significance.: J Conn State Dent Assoc. 1990 Spring;66(1):38-40. Unique Identifier : AIDSLINE MED/93147329; Peters ES Jr; Eisenberg E
Response of dental professionals in Saudi Arabia towards hepatitis B vaccine and glove wearing.: Odontostomatol Trop. 1991 Jun;14(2):24-8. Unique Identifier : AIDSLINE MED/93149927; al-Ruhaimi KA; Oral & Maxillofacial Surgery Department of Biomedical Dental; Sciences College of Dentistry, King Saud University.; Dental specialists, dental general practitioners, dental assistants and hygienists at the medical province of Riyadh (95, 111, 141 and 14 respectively), were surveyed to ascertain their uptake of vaccination against the hepatitis B virus. Only 25.3% of dental specialists, 14.4% of dental practitioners, 25.5% of dental
[Human immunodeficiency virus (HIV) and drug dependence]: Acta Psiquiatr Psicol Am Lat. 1991 Dec;37(4):277-81. Unique Identifier : AIDSLINE MED/93150890; Miguez HA; Pecci MC; Consejo Nacional de Investigaciones Cientificas y Tecnicas; (CONICET), Buenos Aires, Argentina.; A research has been carried out at several centers for the treatment of drug abusers in Argentina , during the year 1989. Questions related to HIV infection were included among the topics under study. A questionnaire was filled out by 659 patients from both State-run, and private
[Usefulness of bronchoalveolar gavage in patients with acquired immunodeficiency syndrome]: Pneumonol Alergol Pol. 1991;59(9-10):17-22. Unique Identifier : AIDSLINE MED/93160973; Chosia M; Marsan C; Zakladu Patomorfologii Nowotworow Instytutu Patologii,; Pomorskiej Akademii Medycznej, Szczecinie.; 51 BALFs from HIV positive patients were analysed. In 16 of them Pneumocystis carinii organisms were found. Two methods detecting Pneumocystis carinii were used: Grocott-Gomori, fluorescence Papanicolaou stain. The best staining method turned out to be Grocott-Gomori. The differential count was carried out in 40 BALFs
[Subpopulations of T lymphocytes in bronchoalveolar lavage (BAL) fluid of different interstitial lung diseases]: Pneumonol Alergol Pol. 1991;59(9-10):23-7. Unique Identifier : AIDSLINE MED/93160974; Chosia M; Marsan C; Zakladu Patomorfologii Nowotworow Instytutu Patologii,; Pomorskiej Akademii Medycznej, Szczecinie.; Immunocytochemical examinations using the PAP method with monoclonal antibodies against lymphocytes T (CD3, CD4, CD8) were carried out in 31 BAL s from patients with different interstitial lung diseases. A distinct increase of the CD4 (T helper): CD8 (T suppressor) ratio was found in patients with sarcoidosis and in a
Quantitative analysis of CD6, CD4 and CD8 cell surface molecules compared to the absolute numbers of CD6+, CD4+ and CD8+ T-cells in peripheral blood in patients with HIV-infection.: J Clin Lab Immunol. 1991 Aug;35(4):157-63. Unique Identifier : AIDSLINE MED/93164214; Gruber R; Endl J; Froschl M; Rieber EP; Ziegler-Heitbrock HW; Riethmuller G; Institut fur Immunologie, Universitat Munchen, FRG.; T lymphocyte subsets were determined on blood samples from 16 HIV-seropositive patients with manifest AIDS (CDC IV), 24 HIV-seropositive patients with lymphadenopathy syndrome (LAS, CDC III), 16 HIV-seropositive clinical healthy persons (CDC II) and 11 HIV-seronegative homosexuals as control group. Absolute numbers of
Expression and release of IL-2 receptor and production of IL-2 by activated T lymphocyte subsets.: J Clin Lab Immunol. 1991 Sep;36(1):27-32. Unique Identifier : AIDSLINE MED/93164222; Shahabuddin S; Department of Pathology, Riyadh Armed Forces Hospital, Saudi; Arabia.; T lymphocyte subsets differ in expression of cell surface antigen and functional properties. Both CD4+ and CD8+ subsets express interleukin-2 receptor (IL-2R) following their activation in vitro. In the present investigation T lymphocyte subsets were activated by different mitogens and IL-2R expression was enumerated
The role of neopterin as a monitor of cellular immune activation in transplantation, inflammatory, infectious, and malignant diseases.: Crit Rev Clin Lab Sci. 1992;29(3-4):307-41. Unique Identifier : AIDSLINE MED/93143865; Fuchs D; Weiss G; Reibnegger G; Wachter H; Institute for Medical Chemistry and Biochemistry, University of; Innsbruck, Austria.; The accumulated knowledge about the organization and function of the human immune system contributes to a better understanding of the pathogenesis of most diverse disorders and is opening new avenues for therapeutic regimens. To gain further insight into the complex interactions within the components of the immune sys
Quarterly Communicable Disease Review. April to June 1992. From the PHLS Communicable Disease Surveillance Centre.: J Public Health Med. 1992 Dec;14(4):408-17. Unique Identifier : AIDSLINE MED/93143988; Cartwright KA; Evans BG; Hall SM; Healing TD; Noone A
In vitro infection of human macrophages by human T-cell leukemia/lymphotropic virus type I (HTLV-I).: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1845-9. Unique Identifier : AIDSLINE MED/93143992; Koralnik IJ; Lemp JF Jr; Gallo RC; Franchini G; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, MD 20892.; HTLV-I is associated with a neurological syndrome designated Tropical Spastic Paraparesis/HTLV-I associated myelopathy (TSP/HAM). To determine whether HTLV-I can replicate in human primary macrophages and thus contribute to HTLV-I dissemination in the nervous system, elutriated human macrophages were infected cell-fre
Coexistence of human T-lymphotropic virus types I and II among the Wayuu Indians from the Guajira Region of Colombia.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1851-5. Unique Identifier : AIDSLINE MED/93143993; Duenas-Barajas E; Bernal JE; Vaught DR; Briceno I; Duran C; Yanagihara R; Gajdusek DC; Laboratory of Central Nervous System Studies, National Institute; of Neurological Disorders and Stroke, National Institutes of; Health, Bethesda, MD.; High prevalences of human T-lymphotropic virus type II (HTLV-II) infection have been found recently among certain Amerindian groups in North, Central, and South America. To determine if the Amerindians of Colombia are similarly affe
Evaluation of enzyme immunoassay using a recombinant envelope protein expressed in insect cells for serological confirmation of HTLV-I infection.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1857-61. Unique Identifier : AIDSLINE MED/93143994; Yamashita K; Maekawa M; Mitani K; Wakamiya M; Ogino T; Miyamura K; Baba K; Yamamoto Y; Nyunoya H; Shimotohno K; et al; AIDS Research Center, National Institute of Health, Tokyo, Japan.; A recombinant human T-lymphotropic virus type I (HTLV-I) envelope protein expressed in insect cells using a recombinant baculovirus was employed as the antigen in an enzyme immunoassay (renvEIA). Peripheral blood samples were obtained from asymptomatic carriers or healthy individuals. Plasma was tested for HTLV-I anti
Association of mycoplasma with HIV-1 and HTLV-I in human T lymphocytes.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1863-8. Unique Identifier : AIDSLINE MED/93143995; Phillips DM; Pearce-Pratt R; Tan X; Zacharopoulos VR; Population Council, New York, NY 10021.; Recent findings from a number of investigators suggest associations between mycoplasma and HIV or AIDS. We used a quantitative morphometric technique to analyze electron micrographs of human T lymphocytes that were infected with both mycoplasma and/or HIV-1. We observed that lymphocytes which were associated with HIV-
Genetic variants of HIV-1 in Thailand.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1887-95. Unique Identifier : AIDSLINE MED/93143998; McCutchan FE; Hegerich PA; Brennan TP; Phanuphak P; Singharaj P; Jugsudee A; Berman PW; Gray AM; Fowler AK; Burke DS; Henry M. Jackson Foundation Research Laboratory, Rockville, MD; 20850.; Serosurveys conducted prior to 1988 indicated a very low level of HIV-1 infection in Thailand , even among high-risk groups. The Ministry of Health has reported a dramatic increase in HIV-1 infection during the last three years. The geographic and demographic distribution of the e
Characterization of the specificity of the human antibody response to the V3 neutralization domain of HIV-1.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1897-908. Unique Identifier : AIDSLINE MED/93143999; Zwart G; Wolfs TF; Valk M; Van der Hoek L; Kuiken CL; Goudsmit J; Human Retrovirus Laboratory, Academic Medical Center, Amsterdam,; The Netherlands.; The major neutralization domain of HIV-1, contained in the third variable region (V3) of the external envelope, is highly variable at positions flanking a conserved glycine-proline-glycine sequence. We investigated the relation between V3 sequences of HIV-1 variants circulating in a host and that host s antibody speci
Reactivities of HIV-1 gag-derived peptides with antibodies of HIV-1-infected and uninfected humans.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1909-17. Unique Identifier : AIDSLINE MED/93144000; Haist S; Marz J; Wolf H; Modrow S; Medizinische Mikorbiologie und Hygiene, Universitat Regensburg,; Germany.; A group of 41 peptides, each 24 amino acids long and overlapping with each other by 12 residues spanning the total gag open reading frame (orf) of HIV-1 (HTLV-IIIBH 10 isolate) were synthesized using Fmoc chemistry. The purified compounds were used in ELISA assays and tested for antibody reactivities in sera of human
Anti-CD4 antibodies are associated with HIV-1 seroconversion and may be detectable before anti-HIV-1 antibodies. The Multicenter AIDS Cohort Study.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1919-27. Unique Identifier : AIDSLINE MED/93144001; Keiser P; Keay S; Wasserman S; Wecksler W; Division of Infectious Diseases, University of Maryland School of; Medicine, Baltimore 21201.; We examined the sera from 14 HIV-1 seroconverters for the presence of autoantibodies against CD4. Anti-CD4 antibodies were detected in the serum of 11 of 13 HIV-1-infected persons at the time of HIV-1 seroconversion. In 6 of 14 persons from whom a serum was obtained prior to HIV-1 seroconversion, anti-CD4 antibodies w
A CD4-derived peptide carrier blocks acute HIV-1 infection in vitro and binds to gp120 in the presence of Walter-Reed stage 1-6 HIV+ sera.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1945-8. Unique Identifier : AIDSLINE MED/93144004; Ghetie V; Wheeler T; Scott D; Uhr JW; Vitetta ES; Department of Microbiology, University of Texas Southwestern; Medical Center, Dallas 75235-9048.; A peptide containing amino acid residues 41-84 of the CD4 molecule was synthesized and coupled through a thioether bond to human serum albumin. This conjugate bound to gp120 with an affinity that was half that of CD4 and blocked the HIV infection in vitro with an efficacy tenfold lower than that of CD4. More important
On the historical origins of HIV-1 (MN) and (RF).: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1950. Unique Identifier : AIDSLINE MED/93144005; Reitz MS Jr; Guo HG; Oleske J; Hoxie J; Popovic M; Read-Connole E; Markham P; Streicher H; Gallo RC
[A nurse for all times (interview by Siv Barstad)]: J Sykepleien. 1992 Sep 21;80(15):14-6. Unique Identifier : AIDSLINE MED/93144015; Eihuns H
[Nursing for the most dangerous (interview by Siv Barstad)]: J Sykepleien. 1992 Sep 21;80(15):20-2. Unique Identifier : AIDSLINE MED/93144018; Figenschou L
[Professionally competent, but lacking good manners (interview by Siv Barstad)]: J Sykepleien. 1992 Nov 16;80(19):10. Unique Identifier : AIDSLINE MED/93144041; Iversen I
[Untraditional vacation for disabled and nurses (interview by Siv Barstad)]: J Sykepleien. 1992 Nov 16;80(19):12-3. Unique Identifier : AIDSLINE MED/93144043; Vege A
[Many challenges as chief delegate (interview by Siv Barstad)]: J Sykepleien. 1992 Nov 16;80(19):18-9. Unique Identifier : AIDSLINE MED/93144045; Lokken BN
World AIDS Day [news]: Nurs Stand. 1992 Dec 9-15;7(12):11. Unique Identifier : AIDSLINE MED/93144139
AIDS focus. Alcohol and unsafe sex.: Nurs Stand. 1992 Dec 9-15;7(12):50-3. Unique Identifier : AIDSLINE MED/93144151; Scott J
AIDS focus. Sexual issues for people with learning difficulties.: Nurs Stand. 1992 Dec 9-15;7(12):54-5. Unique Identifier : AIDSLINE MED/93144152; Brown H
AIDS focus. HIV roundup.: Nurs Stand. 1992 Dec 9-15;7(12):56. Unique Identifier : AIDSLINE MED/93144153; Weller B
[Detection of HBV-DNA in peripheral blood mononuclear cells of anti-HIV-positive patients and its relation to other serological markers of HBV]: Enferm Infecc Microbiol Clin. 1992 Oct;10(8):445-50. Unique Identifier : AIDSLINE MED/93144371; Sunen E; Malave C; Sarria L; Gorrino C; Campelo C; Martinez J; Cisterna R; Departamento de Microbiologia e Inmunologia, Universidad del; Pais Vasco, Hospital Civil de Bilbao.; HBV infection has been investigated in 47 anti-human HIV positive patients in relation to a similar group of 33 anti-HIV negative patients. Serological HBV markers were found in 87% of anti-HIV positive patients. The difference in markers of viral replication (HBeAg, HBV-DNA) was not statistically significant between
[Myopathy and zidovudine]: Enferm Infecc Microbiol Clin. 1992 Oct;10(8):474-6. Unique Identifier : AIDSLINE MED/93144377; Mateo O; Gato A; Ballesteros P; Benito L; Pontes MJ; Esquinas G; Servicio de Medicina Interna, Hospital Universitario de Getafe,; Madrid.; BACKGROUND: The aim of this study was to evaluate the frequency of appearance of myopathy in a group of patients treated with zidovudine. METHODS: A prospective study of 37 patients with positive serology for HIV treated over 180 days with zidovudine was carried out with evaluation of the clinical history, physical ex
[Ulcerated pulmonary infiltration in an intravenous drug addict]: Enferm Infecc Microbiol Clin. 1992 Nov;10(9):549-51. Unique Identifier : AIDSLINE MED/93144401; Garcia F; Garcia Quintana AM; Capdevila JA; Ocana I; Servicio de Medicina Interna-Patologia Infecciosa, Hospital; General Universitario de la Vall d'Hebron, Barcelona.
[Pneumonia caused by Legionella pneumophila and acquired immunodeficiency syndrome (letter) (see comments)]: Enferm Infecc Microbiol Clin. 1992 Nov;10(9):561-2. Unique Identifier : AIDSLINE MED/93144408; Barbe J; Capdevila JA; Garcia Quintana A; Ferrer A
[HIV infection and chronic brucellosis (letter) (see comments)]: Enferm Infecc Microbiol Clin. 1992 Nov;10(9):566-7. Unique Identifier : AIDSLINE MED/93144412; Martin I; Ramos C; Gutierrez A; Arazo P; Aguirre JM
Insulin and IGF-I stimulate normal and virally transformed T-lymphocyte cell growth in vitro.: Brain Behav Immun. 1992 Dec;6(4):377-86. Unique Identifier : AIDSLINE MED/93144828; Geffner ME; Bersch N; Golde DW; Department of Pediatrics, UCLA School of Medicine 90024.; We used normal and HTLV-II-transformed T-lymphocytes as target cells to study clonal proliferative responses to physiologic and supraphysiologic concentrations of insulin and IGF-I. Responses of both growth factors were measured in the presence and absence of alpha IR-3, and IGF-I receptor-blocking antibody. A biphasi
Inhibition of human immunodeficiency virus-1 proliferation by liposome-encapsulated sense DNA to the 5' tat splice acceptor site.: Antisense Res Dev. 1992 Fall;2(3):187-97. Unique Identifier : AIDSLINE MED/93144890; Sullivan SM; Gieseler RK; Lenzner S; Ruppert J; Gabrysiak TG; Peters JH; Cox G; Richer L; Martin WJ; Scolaro MJ; Vestar, Inc., San Dimas, California.; A liposome formulation containing a distearoylphosphatidylethanolamine analog was developed that was endocytosed by both lymphocytes and monocytes. This formulation was used to encapsulate sense and antisense 20-mer oligodeoxynucleotides to the 5 tat splice acceptor site of human immunodeficiency virus type 1. At a D
Cellular uptake and subcellular distribution of phosphorothioate oligonucleotides into cultured cells.: Antisense Res Dev. 1992 Fall;2(3):211-22. Unique Identifier : AIDSLINE MED/93144892; Iversen PL; Zhu S; Meyer A; Zon G; Department of Pharmacology, University of Nebraska Medical; Center, Omaha.; A phosphorothioate oligonucleotide that has been employed to inhibit HIV-1 viral expression in chronically infected H9 cells was examined for cellular uptake and subcellular distribution. The relationship between extracellular oligonucleotide concentration and the distribution and accumulation into subcellular organel
Binding of antisense phosphorothioate oligonucleotides to murine lymphocytes is lineage specific and inducible.: Antisense Res Dev. 1992 Fall;2(3):223-33. Unique Identifier : AIDSLINE MED/93144893; Iversen PL; Crouse D; Zon G; Perry G; Department of Pharmacology, University of Nebraska Medical; Center, Omaha.; A phosphorothioate oligonucleotide that has been employed to inhibit HIV-1 viral expression in chronically infected H9 cells was examined for its ability to associate with murine lymphoid cells. The relationship between cellular oligonucleotide concentration and the lymphoid target tissues is important to the selectio
Estimating the trend of the epidemic of drug use in Italy, 1985-89.: Br J Addict. 1992 Dec;87(12):1643-8. Unique Identifier : AIDSLINE MED/93144901; Rezza G; Dorrucci M; Filibeck U; Serafin I; SE.CE.DAS (Epidemiology Unit and Drug Unit), Ministero della; Sanita, Rome, Italy.; We used data from different sources to estimate the extent and the trend of the epidemic of drug use in Italy in the second half of the 80s. During the study period, the number of subjects attending drug dependency units increased from 13,905 to 61,689. Mortality and morbidity indi
Knowledge of AIDS and HIV among various groups.: Br J Addict. 1992 Dec;87(12):1663-8. Unique Identifier : AIDSLINE MED/93144903; Ralston GE; Dow MG; Rothwell B; Department of Psychological Medicine/Drug Project, Southern; General Hospital, Glasgow, UK.; To date, no cure has been found for HIV/AIDS. Prevention has therefore been the immediate principal aim and a didactic approach has been given a primary role. Studies from the USA indicate that knowledge level may be dictated by membership of particular subcultural groups and the perceived relevance of HIV/AIDS to the
Presumed intraocular lymphoma in a 60-year-old man with AIDS.: Eur J Ophthalmol. 1992 Oct-Dec;2(4):203-4. Unique Identifier : AIDSLINE MED/93144917; Seerp Baarsma G; Roland Smit LM; Rotterdam Eye Hospital, The Netherlands.; A 60-year-old man with AIDS and active pulmonary tuberculosis presented with a rapidly growing chorioretinal tumor. Tuberculostatics had no effect on the tumor but radiation resulted in a quick decrease in its size. It is therefore believed to be a lymphoma. No biopsy was performed. An intraocular lymphoma in a patien
Confronting the challenge of AIDS in the African-American community.: Ethn Dis. 1992 Fall;2(4):358-60. Unique Identifier : AIDSLINE MED/93145001; DiClemente RJ; Center for AIDS Prevention Studies, University of California, San; Francisco 94105.
Correlates of HIV risk behaviors in black and white San Francisco heterosexuals: the population-based AIDS in multiethnic neighborhoods (AMEN) study.: Ethn Dis. 1992 Fall;2(4):361-70. Unique Identifier : AIDSLINE MED/93145002; Peterson JL; Grinstead OA; Golden E; Catania JA; Kegeles S; Coates TJ; Center for AIDS Prevention Studies, University of California, San; Francisco 94105.; This study, the first random household probability sample of unmarried adults in an HIV epicenter, examined the prevalence and correlates of HIV risk behaviors among sexually active unmarried heterosexual white and black adults (n = 848) in San Francisco, California. Racial or gender differences were found in the HIV
Predicting intentions to use condoms among African-American adolescents: the theory of planned behavior as a model of HIV risk-associated behavior.: Ethn Dis. 1992 Fall;2(4):371-80. Unique Identifier : AIDSLINE MED/93145003; Jemmott JB 3d; Jemmott LS; Hacker CI; Department of Psychology, Princeton University, NJ 08544-1010.; The relation of attitudes, subjective norms, and perceived behavioral control to intentions to use condoms was examined among 179 adolescents who completed a confidential self-administered questionnaire prior to participating in a minority youth health conference. Approximately 72% of the adolescents were African Amer
Cultural, gender, and psychosocial influences on HIV-related behavior of African-American female adolescents: implications for the development of tailored prevention programs.: Ethn Dis. 1992 Fall;2(4):381-8. Unique Identifier : AIDSLINE MED/93145004; Wingood GM; DiClemente RJ; Department of Health and Social Behavior, Harvard School of; Public Health, Boston, MA 02115.; This paper presents epidemiologic data describing the risk of HIV/AIDS and sexually transmitted diseases for African-American female adolescents relative to their white peers. Diverse cultural, psychosocial, and gender influences affect behavior; these should be considered in the development and implementation of cult
'Many are called...': participation by minority leaders in an AIDS intervention in San Francisco.: Ethn Dis. 1992 Fall;2(4):389-401. Unique Identifier : AIDSLINE MED/93145005; Morales ES; Fullilove MT; California School of Professional Psychology, Berkeley/Alameda,; MERIT Institute, San Francisco.; Though the AIDS epidemic has posed a significant threat to minority people, especially African Americans and Latinos, minority community response to the epidemic has lagged significantly behind the organized efforts initiated by the European-American gay community. To test the efficacy of an educational intervention i
Quantitative or semi-quantitative PCR: reality versus myth.: PCR Methods Appl. 1992 Aug;2(1):1-9. Unique Identifier : AIDSLINE MED/93145045; Ferre F; Immune Response Corporation, Carlsbad, California 92008.
A method for nested PCR with single closed reaction tubes.: PCR Methods Appl. 1992 Aug;2(1):60-5. Unique Identifier : AIDSLINE MED/93145054; Yourno J; Wadsworth Center for Laboratories and Research, New York State; Department of Health, Albany 12201-0509.; Toward the goal of reducing diagnostic false positives while retaining high sensitivity, a closed-tube nested PCR procedure has been developed for detecting low-copy-number human immunodeficiency virus (HIV) gag target DNA sequences. Master mix for amplification 2, in a hanging gel matrix at the reaction tube top, rem
The newest science and its newest disease.: Conn Med. 1992 Nov;56(11):649-50. Unique Identifier : AIDSLINE MED/93145631; Massey RU; Department of Community Medicine and Health Care, University of; Connecticut School of Medicine, Farmington.
Lymphomas in mice with retrovirus-induced immunodeficiency.: Curr Top Microbiol Immunol. 1992;182:395-8. Unique Identifier : AIDSLINE MED/93145710; Tang Y; Fredrickson TN; Chattopadhyay SK; Hartley JW; Morse HC 3d; Laboratory of Immunopathology, NIAID, NIH, Bethesda, MD.
Does HIV infection of B lymphocytes initiate AIDS lymphoma? Detection by PCR of viral sequences in lymphoma tissue.: Curr Top Microbiol Immunol. 1992;182:399-407. Unique Identifier : AIDSLINE MED/93145711; Astrin SM; Schattner E; Laurence J; Lebman RI; Rodriguez-Alfageme C; Fox Chase Cancer Center, Philadelphia, PA 19111.; Individuals infected with HIV (Human Immunodeficiency Virus) frequently develop B cell non-Hodgkins lymphoma. Although previous studies have failed to document the presence of HIV sequences in these tumors, the recent demonstration of malignant transformation of primary B lymphocytes by HIV-1 has prompted us to reinve
Transactivation of the c-myc gene by HTLV-1 tax is mediated by NFkB.: Curr Top Microbiol Immunol. 1992;182:421-4. Unique Identifier : AIDSLINE MED/93145713; Duyao MP; Kessler DJ; Spicer DB; Sonenshein GE; Biochemistry Department, Boston University School of Medicine, MA; 02118.
Kaposi sarcoma involving bone in an HIV negative patient.: Eur J Radiol. 1992 Oct;15(3):200-2. Unique Identifier : AIDSLINE MED/93145985; Martinez-Sapina MJ; Mosquera J; Castro JM; Comesana ML; Rodriguez E; Menendez MD; Department of Radiology, Hospital Juan Canalejo, La Coruna,; Spain.
A leader in Canada's response to the AIDS crisis.: Hosp Community Psychiatry. 1992 Nov;43(11):1140-1. Unique Identifier : AIDSLINE MED/93146543
High-risk sex behavior among young street-recruited crack cocaine smokers in three American cities: an interim report. The Multicenter Crack Cocaine and HIV Infection Study Team.: J Psychoactive Drugs. 1992 Oct-Dec;24(4):363-71. Unique Identifier : AIDSLINE MED/93148011; Edlin BR; Irwin KL; Ludwig DD; McCoy HV; Serrano Y; Word C; Bowser BP; Faruque S; McCoy CB; Schilling RF; et al; Division of HIV/AIDS, Centers for Disease Control, Atlanta,; Georgia 30333.; Since crack cocaine appeared in urban areas in the United States in the mid-1980s, reports have suggested that crack smokers may be at increased risk of sexually transmitted diseases (STDs), including infection with HIV, because they have multiple sex partners, trade sex for money or d
Crack cocaine use and sexual activity in Miami, Florida.: J Psychoactive Drugs. 1992 Oct-Dec;24(4):373-80. Unique Identifier : AIDSLINE MED/93148012; Weatherby NL; Shultz JM; Chitwood DD; McCoy HV; McCoy CB; Ludwig DD; Edlin BR; Comprehensive Drug Research Center, University of Miami School of; Medicine, Florida 33136.; Data are analyzed from the Multicenter Study of Crack Cocaine and HIV Infection in Miami, Florida, examining interrelationships among use of crack cocaine, use of other drugs, sexual activity, and exchange of sex for money and drugs. This study was designed to recruit two groups of approximately equal size: persons wh
A gender comparison of health status among users of crack cocaine.: J Psychoactive Drugs. 1992 Oct-Dec;24(4):389-97. Unique Identifier : AIDSLINE MED/93148014; McCoy HV; Miles C; Department of Public Health, Florida International University.; This study examines a population of inner-city crack cocaine users in Miami, Florida. Many study participants were also injection drug users; others were the sexual partners of injection drug users. In general, the self-reported health status of the study population was good, but men perceived their health in a more p
Crack use and correlates of use in a national population of street heroin users. The National AIDS Research Consortium.: J Psychoactive Drugs. 1992 Oct-Dec;24(4):411-6. Unique Identifier : AIDSLINE MED/93148016; McBride DC; Inciardi JA; Chitwood DD; McCoy CB; Andrews University, Department of Behavioral Sciences, Berrien; Springs, Michigan 49104.; Traditionally, researchers and clinicians have viewed street heroin users as representing an end point in a drug-using career. It is toward this population that major national treatment efforts have been directed. Concomitant with the historical national concern about heroin use has been concern about the increase in
Human immunodeficiency virus (HIV) and HIV infected cells in saliva and salivary glands of a patient with systemic lupus erythematosus.: J Rheumatol. 1992 Nov;19(11):1810-2. Unique Identifier : AIDSLINE MED/93148271; Yeh CK; Fox PC; Goto Y; Austin HA; Brahim JS; Fox CH; Clinical Investigations and Patient Care Branch, NIDR, National; Institutes, of Health, Bethesda, MD 20892.; A young woman with systemic lupus erythematosus (SLE) was infected with human immunodeficiency virus 1 (HIV-1) and about 6 years later developed persistent bilateral parotid gland enlargement. It was unclear whether this represented salivary gland involvement as a component of her SLE (secondary Sjogren s syndrome) or
Vasculitis with eosinophilia and digital gangrene in a patient with acquired immunodeficiency syndrome.: J Rheumatol. 1992 Nov;19(11):1813-6. Unique Identifier : AIDSLINE MED/93148272; Enelow RS; Hussein M; Grant K; Cupps TR; Druckman D; Mortazavi A; Villaflor ST; Glass-Royal M; Georgetown Department of Medicine, District of Columbia General; Hospital, Washington 20003.; Fewer than 40 cases of vasculitis have been described in the setting of human immunodeficiency virus infection. We describe a patient with the acquired immunodeficiency syndrome (AIDS), a heavy smoker, who developed a syndrome of constitutional symptoms, eosinophilia and digital gangrene. Vasculitis of the digital art
[Environment and nursing (II). Non-communicable occupational health hazards in the hospital]: Taehan Kanho. 1992 Jul-Aug;31(3):12-21. Unique Identifier : AIDSLINE MED/93148561; Paek DM
[Environment and nursing (II). Occupational health care in hospital]: Taehan Kanho. 1992 Jul-Aug;31(3):22-5. Unique Identifier : AIDSLINE MED/93148562; Lee SE
[An experimental activity. The traveling bus for the prevention of AIDS]: Krankenpfl Soins Infirm. 1992 Dec;85(12):12-3. Unique Identifier : AIDSLINE MED/93148596
Energy transformations in the biosynthesis of the immune system: their relevance to the progression and treatment of AIDS.: Med Hypotheses. 1992 Aug;38(4):315-21. Unique Identifier : AIDSLINE MED/93148868; Tanner HA; Dysfunction of the immune system is observed in diseases where metabolic respiration is inhibited. Anabolites that enhance oxidative phosphorylation will provide the ATP essential for the biosynthesis of the cellular components and antibodies of the immune system. The induction of Coenzyme Q10 has been observed to pro
Are sense-antisense peptide interactions between HIV-1 (gp120), CD4, and the proto oncogene product p56lck important?: Med Hypotheses. 1992 Aug;38(4):322-4. Unique Identifier : AIDSLINE MED/93148869; Brown R; Meldrum C; Cousins S; Department of Psychology, University of Newcastle, Callaghan,; Australia.; The finding that codons for hydrophobic and hydrophilic amino acids are generally complemented by codons for hydrophilic and hydrophobic amino acids respectively has led to a novel observation. The antisense peptides coded for by the complementary DNA strand of biologically active peptides are able to bind their activ
Surgery in the age of AIDS: a video.: Nurse Educ. 1992 Nov-Dec;17(6):13. Unique Identifier : AIDSLINE MED/93149500; Blancett SS
AIDS: a caring response.: Nurse Educ. 1992 Nov-Dec;17(6):5. Unique Identifier : AIDSLINE MED/93149509; Gaskins SW; VanderMeer J
[Rhodococcus equi infections in AIDS: personal cases]: Pathologica. 1992 Jul-Aug;84(1092):517-21. Unique Identifier : AIDSLINE MED/93149682; Piersantelli N; Casini-Lemmi M; Cavanna E; Cassola G; Crisalli MP; Guida B; Paladino M; Penco G; Piscopo R; Torresin A; Divisione Malattie Infettive, Ospedali Galliera di Genova.; We report on the occurrence of an uncommon pathogen, Rhodococcus equi (R.e.) in HIV infection. In the period february 1990-July 1991 we performed the diagnosis of R.e. infection (lung, lung-central nervous system) in two infected patients, aged 27 and 31 years, both males, drug addicts, classified as CDC IV. In the fi
Pericardial effusion and its relationship to cardiac disease in children with acquired immunodeficiency syndrome.: Pediatr Radiol. 1992;22(7):548-51. Unique Identifier : AIDSLINE MED/93149714; Mast HL; Haller JO; Schiller MS; Anderson VM; Department of Radiology, State University of New York, Health; Science Center at Brooklyn, Downstate Medical Center.; Over 200 children with acquired immunodeficiency syndrome (AIDS) have been followed at our institution. We retrospectively evaluated 45 children from the above group. 26 of the 45 children had a pericardial effusion documented at echocardiography and/or at post-mortem examination. This report describes the association
Two smooth muscle tumors in the airway of an HIV-infected child.: Pediatr Radiol. 1992;22(7):552-3. Unique Identifier : AIDSLINE MED/93149715; Balsam D; Segal S; Department of Radiology, Nassau County Medical Center, East; Meadow, NY 11554.; Tumors of smooth muscle origin are rare in childhood. We report a case of multiple bronchial leiomyomata in a seven year old girl with clinical HIV infection who presented with new onset of wheezing. Clinical details of this case have been published elsewhere, but without imaging studies [1].
Bronchiectasis in children with lymphocytic interstitial pneumonia and acquired immune deficiency syndrome. Plain film and CT observations.: Pediatr Radiol. 1992;22(8):603-6; discussion 606-7. Unique Identifier : AIDSLINE MED/93149735; Amorosa JK; Miller RW; Laraya-Cuasay L; Gaur S; Marone R; Frenkel L; Nosher JL; Department of Radiology, UMDNJ Robert Wood Johnson Medical; School, New Brunswick 08903-0019.; In a review of 77 HIV positive children seen between 1981 and 1990, 32 were diagnosed as having lymphocytic interstitial pneumonitis). Four of the LIP group developed bronchiectasis, a finding not previously reported. The precise factors leading to the bronchiectasis are unclear. All patients had chronically consolida
A welcome step [news]: Nurs Times. 1992 Oct 7-13;88(41):18. Unique Identifier : AIDSLINE MED/93149787; Mason P
Comparative pharmacokinetics of zidovudine in healthy volunteers and in patients with AIDS with and without hepatic disease.: Pharmacotherapy. 1992;12(6):429-34. Unique Identifier : AIDSLINE MED/93149863; Fletcher CV; Rhame FS; Beatty CC; Simpson M; Balfour HH Jr; Department of Pharmacy Practice, College of Pharmacy, University; of Minnesota, Minneapolis 55455.; To understand whether disease caused by the human immunodeficiency virus (HIV) affects zidovudine disposition, we compared the drug s pharmacokinetics in six healthy volunteers; six persons with the acquired immunodeficiency syndrome (AIDS) and no evidence of gastrointestinal (nausea, vomiting, diarrhea), renal (eleva
Granulocyte-macrophage colony-stimulating factor and zidovudine in the treatment of neutropenia and human immunodeficiency virus infection.: Pharmacotherapy. 1992;12(6):455-61. Unique Identifier : AIDSLINE MED/93149868; Hewitt RG; Morse GD; Department of Medicine, State University of New York, Buffalo.; Granulocyte-macrophage colony-stimulating factor (GMCSF) is a hematopoietic protein that has been studied both in vitro and in vivo in human immunodeficiency virus (HIV) infection. Since both HIV infection primarily and zidovudine (formerly AZT ) treat
Pediatric HIV-1 infection: a clinical overview.: Pediatr Dermatol. 1992 Dec;9(4):323-5. Unique Identifier : AIDSLINE MED/93149931; Scott GB; Division of Pediatric Infectious Disease and Immunology,; University of Miami School of Medicine, Florida.; Several questions remain unanswered including the timing of perinatal transmission, maternal factors predisposing to perinatal transmission of HIV-1, the best methods for early diagnosis in the neonate, and means of preventing perinatal HIV-1 infection. Significant advances have been made in the early diagnosis of HIV
Cutaneous manifestations of pediatric HIV infection.: Pediatr Dermatol. 1992 Dec;9(4):326-8. Unique Identifier : AIDSLINE MED/93149932; Prose NS; Duke University Medical Center, Durham, North Carolina.; Children who are infected with human immunodeficiency virus may develop a wide variety of mucocutaneous manifestations, such as skin infections, tumors, and inflammatory skin disorders. The most significant infectious diseases are candidiasis, dermatophytosis, herpes simplex, herpes zoster, and pyoderma. Inflammatory
[Value of thiabendazole in scabies resistant to local treatment in HIV infected patients (letter)]: Presse Med. 1992 Nov 14;21(38):1821-2. Unique Identifier : AIDSLINE MED/93149988; Allegre T; Cailleres S; Lota I; Tadrist Z; Coulet F; Bellon O; Blanc AP
AIDS acquired by drug consumption and other noncontagious risk factors.: Pharmacol Ther. 1992;55(3):201-77. Unique Identifier : AIDSLINE MED/93150052; Duesberg PH; Department of Molecular and Cell Biology, University of; California, Berkeley 94720.; The hypothesis that human immunodeficiency virus (HIV) is a new, sexually transmitted virus that causes AIDS has been entirely unproductive in terms of public health benefits. Moreover, it fails to predict the epidemiology of AIDS, the annual AIDS risk and the very heterogeneous AIDS diseases of infected persons. The
Pokeweed antiviral protein: ribosome inactivation and therapeutic applications.: Pharmacol Ther. 1992;55(3):279-302. Unique Identifier : AIDSLINE MED/93150053; Irvin JD; Uckun FM; Department of Chemistry, Southwest Texas State University, San; Marcos 78666.; Pokeweed antiviral protein (PAP) is a ribosome-inactivating protein (RIP) that inactivates ribosomes by the removal of a single adenine from ribosomal RNA. The studies summarized in our review concern the nature and application of this novel therapeutic agent. We describe how researchers continue to elucidate the stru
[Care, work accidents and preventive treatment with AZT]: Soins Chir. 1992 Aug-Sep;(138-139):53-4. Unique Identifier : AIDSLINE MED/93150224; Bonifassi L; Pradier C
HIV/AIDS in prisons.: Scott Med J. 1992 Oct;37(5):132-7. Unique Identifier : AIDSLINE MED/93150281; McKee KJ; Power KG; Department of Medicine, Ninewells Hospital and Medical School,; Dundee.
AIDS on the college campus.: S D Nurse. 1992 Dec;34(4):11. Unique Identifier : AIDSLINE MED/93150298; Kropenske L
The clinical applications of colony-stimulating factors in acquired immunodeficiency syndrome.: Semin Hematol. 1992 Oct;29(4 Suppl 3):33-7. Unique Identifier : AIDSLINE MED/93150321; Scadden DT; Harvard Medical School, Division of Hematology/Oncology, Boston,; MA.
Prior episode of sexually transmitted disease and subsequent sexual risk-reduction practices. A need for improved risk-reduction interventions.: Sex Transm Dis. 1992 Nov-Dec;19(6):326-30. Unique Identifier : AIDSLINE MED/93150380; O'Campo P; Deboer M; Faden RR; Kass N; Gielen AC; Anderson J; Department of Maternal and Child Health, Johns Hopkins School of; Hygiene and Public Health, Baltimore, Maryland.; Persons with a history of a sexual transmitted disease (STD) are at increased risk for infection with human immunodeficiency virus (HIV). The extent to which women with a previous history of a STD report currently practicing protective behaviors against STD transmission is examined. Specifically, whether having experi
Age at first coitus. A marker for risky sexual behavior in women.: Sex Transm Dis. 1992 Nov-Dec;19(6):331-4. Unique Identifier : AIDSLINE MED/93150381; Greenberg J; Magder L; Aral S; Division of STD and HIV Prevention, Centers for Disease Control,; Atlanta, GA 30333.; This study examines whether riskier sexual behavior or duration of sexual experience explains why women who become sexually active earlier in life have a higher prevalence of sexually transmitted disease (STD). Responses to a self-administered questionnaire on risk behavior from 4,342 single women attending Planned Pa
Sexual patterns and human immunodeficiency virus infection among homosexuals in Taiwan.: Sex Transm Dis. 1992 Nov-Dec;19(6):335-8. Unique Identifier : AIDSLINE MED/93150382; Ko YC; Chang SJ; School of Public Health, Kaohsiung Medical College, Taiwan,; Republic of China.; Between 1988 and 1991, 64 homosexual men and 43 bisexual men were screened for human immunodeficiency virus (HIV) in Southern Taiwan ; 5 of them were found to carry HIV antibodies. According to a self-administered questionnaire compl
[Fertility in men infected with HIV]: Minerva Urol Nefrol. 1992 Jul-Sep;44(3):228-9. Unique Identifier : AIDSLINE MED/93150401; Di Nola F
[AIDS in transplantation]: Minerva Urol Nefrol. 1992 Jul-Sep;44(3):230-1. Unique Identifier : AIDSLINE MED/93150402; Di Nola F
[Sexually transmissible diseases (editorial)]: Soins Gynecol Obstet Pueric Pediatr. 1992 Nov;(138):3. Unique Identifier : AIDSLINE MED/93150436; Goddet B
[Human immunodeficiency virus]: Soins Gynecol Obstet Pueric Pediatr. 1992 Nov;(138):42-4. Unique Identifier : AIDSLINE MED/93150440; Barin F
Cutaneous findings associated with HIV disease including AIDS: experience from Sub Saharan Africa.: Trop Doct. 1992;22 Suppl 1:35-41;60. Unique Identifier : AIDSLINE MED/93150558; Pallangyo KJ; Department of Medicine, Faculty of Medicine, Muhimbili Medical; Centre, Dar es Salaam, Tanzania.; Cutaneous manifestations are common in patients with HIV infection and tend to be more frequent as immunodeficiency progresses. In the initial stage of HIV infection a transient maculopapular-rash may appear. During the otherwise asymptomatic phase that follows, patients may develop seborrhoeic dermatitis, persistent
No evidence of new HIV-like epidemic.: Soz Praventivmed. 1992;37(6):309. Unique Identifier : AIDSLINE MED/93150726
Detection of T-lymphocytes in the peripheral blood and lymphoid tissues of cattle using a variant of the E-rosette test and monoclonal antibodies.: Zentralbl Veterinarmed [B]. 1992 Nov;39(9):633-40. Unique Identifier : AIDSLINE MED/93150743; Vojtisek P; Knotek Z; Horin P; Madr P; University of Veterinary Science, Institute of Animal Breeding; and Genetics, Brno, CSFR.; A simple and efficient variant of the E-rosette test based on addition of dextran to the incubation media is described. This variant 1) does not include B cells 2) involves some CD2+ null cells as described 3) is not inhibited by anti-CD5 antibody 4) correlates with CD2 expression 5) detects specific changes in the re
[Radiologic manifestations of AIDS in the thorax]: Acta Med Port. 1992 Nov;5(10):539-45. Unique Identifier : AIDSLINE MED/93150943; Lucas MF; Servico de Radiologia, Hospital de Curry Cabral, Lisboa.; In AIDS, pulmonary involvement is the main cause of morbidity and death. In this article the author makes a short report of the illness and a review of its radiological pulmonary images, in what concerns infections, tumoral, non-infections and non-tumoral pathology. Finally, the author proposes a radiological follow-u
Variability in reprocessing policies and procedures for flexible fiberoptic endoscopes in Massachusetts hospitals.: Am J Infect Control. 1992 Dec;20(6):283-90. Unique Identifier : AIDSLINE MED/93151461; Reynolds CD; Rhinehart E; Dreyer P; Goldmann DA; Division of Health Care Quality, Massachusetts Department of; Public Health, Boston.; BACKGROUND: Concern is increasing regarding the risk of transmission of blood-borne pathogens by means of improperly reprocessed medical devices. METHODS: On-site surveys of policies and practices were performed in 18 reprocessing areas in eight randomly selected hospitals in Massachusetts to assess current practices
Infection of cultured human adrenal cells by different strains of HIV.: AIDS. 1992 Dec;6(12):1437-43. Unique Identifier : AIDSLINE MED/93152026; Barboza A; Castro BA; Whalen M; Moore CC; Parkin JS; Miller WL; Gonzalez-Scarano F; Levy JA; Department of Medicine, University of California, School of; Medicine, San Francisco 94143-0128.; OBJECTIVE: To determine whether human adrenal cells can be infected by HIV. METHODS: Cultured human fetal adrenal cells and the SW13 human adrenocortical carcinoma cell line were inoculated with several HIV-1 and HIV-2 strains. Virus replication was detected by viral core antigen enzyme-linked immunosorbent and revers
Zidovudine-resistant and -sensitive HIV-1 isolates from patients on drug therapy: in vitro studies evaluating level of replication-competent viruses and cytopathogenicity.: AIDS. 1992 Dec;6(12):1445-9. Unique Identifier : AIDSLINE MED/93152027; Tremblay M; Rooke R; Wainberg MA; Departement de Microbiologie, Faculte de Medecine, Universite; Laval, Ste-Foy, Quebec, Canada.; OBJECTIVE: To compare biological properties of zidovudine-resistant variants of HIV-1 isolated from subjects on long-term drug therapy with drug-sensitive parental isolates obtained from the same patients before initiation of treatment. METHODS: Clinical HIV-1 strains were isolated following co-incubation of patient p
Immunization in children with HIV seropositivity at birth: antibody response to polio vaccine and tetanus toxoid.: AIDS. 1992 Dec;6(12):1465-9. Unique Identifier : AIDSLINE MED/93152030; Barbi M; Biffi MR; Binda S; Clerici-Schoeller M; Ferraris G; Luraschi C; Masella P; Mazzoni P; Pozzi A; Pregliasco F; et al; Istituto di Virologia, Universita di Milano, Italy.; OBJECTIVE: To evaluate the humoral response to routine childhood immunization of HIV-infected children. DESIGN: Response rate, antibody titres and persistence after polio and tetanus vaccination were compared in 72 children with HIV seropositivity at birth and divided according to HIV infection status as determined by
Eflornithine versus cotrimoxazole in the treatment of Pneumocystis carinii pneumonia in AIDS patients.: AIDS. 1992 Dec;6(12):1489-93. Unique Identifier : AIDSLINE MED/93152034; Smith DE; Davies S; Smithson J; Harding I; Gazzard BG; AIDS Research Unit, Westminster Hospital, London, UK.; OBJECTIVES: To compare cotrimoxazole and eflornithine as primary treatment for first-episode Pneumocystis carinii pneumonia (PCP). DESIGN: Prospective open-labelled study. METHODS: Patients were randomized to eflornithine (400 mg/kg daily, as a continuous intravenous infusion) or cotrimoxazole (3.84 g twice daily, int
HIV infection and breast-feeding: policy implications through a decision analysis model.: AIDS. 1992 Dec;6(12):1505-13. Unique Identifier : AIDSLINE MED/93152037; Hu DJ; Heyward WL; Byers RH Jr; Nkowane BM; Oxtoby MJ; Holck SE; Heymann DL; Division of HIV/AIDS, National Center for Infectious Diseases,; Centers for Disease Control, Atlanta, Georgia.; OBJECTIVES: (1) To develop a comprehensive decision analysis model to compare mortality associated with HIV transmission from breast-feeding with the mortality from not breast-feeding in different populations and (2) to perform sensitivity analyses to illustrate critical boundaries for guiding research and policy. MET
Estimating the incubation period of paediatric AIDS in Rwanda.: AIDS. 1992 Dec;6(12):1515-20. Unique Identifier : AIDSLINE MED/93152038; Commenges D; Alioum A; Lepage P; Van de Perre P; Msellati P; Dabis F; INSERM U330, Universite de Bordeaux II, France.; OBJECTIVE: To estimate the distribution of the incubation period of paediatric AIDS in Rwanda . DESIGN: Data were collected between February 1984 and December 1990 at the Centre Hospitalier de Kigali (CHK), the capital city of Rwanda, Central Africa. PATIENTS: We used a sample of 68
The epidemiology of HIV-1 infection in urban areas, roadside settlements and rural villages in Mwanza Region, Tanzania.: AIDS. 1992 Dec;6(12):1521-8. Unique Identifier : AIDSLINE MED/93152039; Barongo LR; Borgdorff MW; Mosha FF; Nicoll A; Grosskurth H; Senkoro KP; Newell JN; Changalucha J; Klokke AH; Killewo JZ; et al; National Institute for Medical Research, Mwanza, Tanzania.; OBJECTIVE: To determine the prevalence of HIV-1 infection and to identify the most important risk factors for infection. DESIGN: A cross-sectional population survey carried out in 1990 and 1991 in Mwanza Region, Tanzania . METHODS: Adults aged 15-54 years were selected from the re
No seroconversions among steady sex partners of methadone-maintained HIV-1-seropositive injecting drug users in New York City [published erratum appears in AIDS 1993 Mar;7(3):following 444]: AIDS. 1992 Dec;6(12):1529-33. Unique Identifier : AIDSLINE MED/93152040; Siddiqui NS; Brown LS Jr; Phillips RY; Vargas O; Makuch RW; Division of Medical Services, Evaluation and Research Addiction; Research and Treatment Corporation, Brooklyn, New York.; OBJECTIVE: To assess the incidence of heterosexual HIV-1 transmission from seropositive methadone-maintained injecting drug users (IDU) to their seronegative, non-IDU steady sex partners. DESIGN: A prospective, longitudinal study. SETTING: HIV-1-seropositive IDU and their HIV-1-seronegative, non-IDU steady sex partner
Seroprevalence of HIV infection in rural South Africa.: AIDS. 1992 Dec;6(12):1535-9. Unique Identifier : AIDSLINE MED/93152041; Abdool Karim Q; Abdool Karim SS; Singh B; Short R; Ngxongo S; Medical Research Council (Natal), South Africa.; OBJECTIVES: To establish the prevalence of HIV infection in rural South Africa and to investigate demographic factors that influence this prevalence. DESIGN: An anonymous HIV seroprevalence survey was performed in conjunction with a population-based malaria surveillance programme.
Tat contains a sequence related to snake neurotoxins [letter]: AIDS. 1992 Dec;6(12):1541-2. Unique Identifier : AIDSLINE MED/93152042; Garry RF; Koch G
How necessary is western blot in the follow-up of children of HIV-infected mothers? The European Collaborative Study [letter]: AIDS. 1992 Dec;6(12):1544-5. Unique Identifier : AIDSLINE MED/93152044
False-positive HIV-1 virus cultures using whole blood [letter] [see comments]: AIDS. 1992 Dec;6(12):1545-6. Unique Identifier : AIDSLINE MED/93152045; Schupbach J; Jendis JB; Bron C; Boni J; Tomasik Z
Effectiveness of assays for antibodies to HIV and p24 antigen to detect very recent HIV infections in blood donors. The Retrovirus Study Group of the French Society of Blood Transfusion [letter]: AIDS. 1992 Dec;6(12):1548-50. Unique Identifier : AIDSLINE MED/93152047; Courouce AM; Barin F; Maniez M; Janot C; Noel L; Elghouzzi MH
HIV-1 viraemia during granulocyte-macrophage colony stimulating factor therapy [letter]: AIDS. 1992 Dec;6(12):1550-1. Unique Identifier : AIDSLINE MED/93152048; Lafeuillade A; Tamalet C; Pellegrino P; Tourres C; Vignoli C; Quilichini R
The impact of HIV disease progression on serum lipoproteins [letter]: AIDS. 1992 Dec;6(12):1551-2. Unique Identifier : AIDSLINE MED/93152049; Meenan J; Mooney E; Mosquita N; Johnson AH; Collins P; Feely J; Mulcahy FM
On 'Specific nutrient abnormalities in asymptomatic HIV-1 infection' [letter; comment]: AIDS. 1992 Dec;6(12):1552-3. Unique Identifier : AIDSLINE MED/93152050; Graham NM
HIV prevalence among female street prostitutes attending a health-care drop-in centre in Glasgow [letter]: AIDS. 1992 Dec;6(12):1553-4. Unique Identifier : AIDSLINE MED/93152051; Carr SV; Green ST; Goldberg DJ; Cameron S; Gruer L; Frischer M; Mackie T; Follett E
Surveillance of voluntary HIV testing in Switzerland [letter; comment]: AIDS. 1992 Dec;6(12):1555. Unique Identifier : AIDSLINE MED/93152052; Estermann J; Paget J; Gebhardt M
International travel and AIDS risk in South Korea [letter]: AIDS. 1992 Dec;6(12):1555-7. Unique Identifier : AIDSLINE MED/93152053; Choi KH; Catania JA; Coates J; Hyung LD; Hearst N
Meningococcal meningitis and HIV infection: results from a case-control study in western Uganda [letter]: AIDS. 1992 Dec;6(12):1557-8. Unique Identifier : AIDSLINE MED/93152054; Kipp W; Kamugisha J; Rehle T
Does laboratory recovery of Pneumocystis carinii always mean clinically significant disease? [letter]: AIDS. 1992 Dec;6(12):1558-9. Unique Identifier : AIDSLINE MED/93152055; Contini G; Romani R; Vullo V; Delia S; Sorice F
[ORL manifestations in HIV patients. Report of 156 cases]: Acta Otorrinolaringol Esp. 1992 Sep-Oct;43(5):317-20. Unique Identifier : AIDSLINE MED/93152197; Alarcos Tamayo E; Blasco Redondo R; Alarcos Llorach A; del Pozo Perez MA; Vielba A; Servicio de ORL, Hospital Clinico de Valladolid.; The study of 156 cases HIV infected patients put forward the high incidence of ENT manifestations in these cases. Cervical lymph nodes are an habitual manifestation of the disease. They appear as a host reaction versus viral infection and often they are the expression of opportunistic infection, Kaposi Sarcoma or lymp
Attitudes towards and use of general practitioner services among homosexual men with HIV infection or AIDS.: Br J Gen Pract. 1992 Mar;42(356):107-10. Unique Identifier : AIDSLINE MED/93152247; Wadsworth E; McCann K; Institute for Social Studies in Medical Care, London.; In a study of 263 homosexual men positive for the human immunodeficiency virus (HIV), it was found that 87% were registered with a general practitioner and of these, 55% said that the general practitioner knew their HIV status. Of the 104 men who had experienced symptoms, 39% had consulted the general practitioner for
Research subjects needed [letter]: Br J Gen Pract. 1992 Mar;42(356):133. Unique Identifier : AIDSLINE MED/93152261; Rose L
Can diphtheria toxin be used for gene therapy of human immunodeficiency virus infection? [letter]: AIDS Res Hum Retroviruses. 1992 Dec;8(12):1949-50. Unique Identifier : AIDSLINE MED/93152266; Caruso M; Tsikas G; Roussel M; Alizon M; Klatzmann D
Effect of a human immunodeficiency virus protease inhibitor on human monocyte function.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):1951-8. Unique Identifier : AIDSLINE MED/93152267; Bugelski PJ; Kaplan JM; Hart TK; Miller J; Laydon JT; Lee JC; Dreyer GB; Kirsh R; Department of Experimental Pathology, SmithKline Beecham; Pharmaceuticals, Philadelphia, PA.; Human immunodeficiency virus (HIV) is the cause of acquired immunodeficiency syndrome (AIDS). Encoded by the HIV genome are several precursor proteins that undergo proteolytic cleavage to yield functional proteins. The env precursor protein is cleaved by a cellular protease. The gag precursor protein of HIV (p55), how
A novel transgenic mouse model for the in vivo evaluation of anti-human immunodeficiency virus type 1 drugs.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):1959-65. Unique Identifier : AIDSLINE MED/93152268; Mehtali M; Munschy M; Ali-Hadji D; Kieny MP; TRANSGENE S.A., Strasbourg, France.; We have developed a binary transgenic mouse system that allows easy in vivo evaluation of new anti-human immunodeficiency virus type 1 (HIV-1) drugs or therapies specifically designed to target the viral transactivator protein (TAT) or long terminal repeat (LTR) functions. This approach consists of a simple genetic cr
Diagrammatization of codon usage in 339 human immunodeficiency virus proteins and its biological implication.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):1967-76. Unique Identifier : AIDSLINE MED/93152269; Chou KC; Zhang CT; Upjohn Research Laboratories, Kalamazoo, MI 49001.; The occurrence frequencies of bases A (adenine), C (cytosine, G (guanine), and T (thymine) occurring in the 1st, 2nd, and 3rd codon positions in the codon usage table of viral genes for the 339 human immunodeficiency virus (HIV) proteins compiled recently have been calculated and diagrammatized. For comparison, the co
Regulatory elements in the human immunodeficiency virus type 1 long terminal repeat LTR (HIV-1) responsive to steroid hormone stimulation [see comments]: AIDS Res Hum Retroviruses. 1992 Dec;8(12):1977-80. Unique Identifier : AIDSLINE MED/93152270; Kolesnitchenko V; Snart RS; Departement de Physiologie Cellulaire, Universite Pierre et; Marie Curie, Paris, France.; Within the long terminal repeat (LTR) of the human immunodeficiency virus type 1 (HIV-1) provirus there exists a steroid hormone-responsive element corresponding to the TGTTCT sequence identified as the glucocorticoid receptor binding element within the LTR of mouse mammary tumor virus. We have used an LTR(HIV-1)-chlo
Heterogeneous expression and coordinate regulation of endogenous retroviral sequences in human peripheral blood mononuclear cells.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):1991-8. Unique Identifier : AIDSLINE MED/93152272; Krieg AM; Gourley MF; Klinman DM; Perl A; Steinberg AD; Department of Internal Medicine, University of Iowa, Iowa City; 52242.; This study examines the expression of human endogenous retroviral or retroviral-like (ERV) sequences in peripheral blood mononuclear cells (PBMC). Probes to 12 human ERV were used in Northern analyses of 38 patients with autoimmune muscle diseases and 31 blood donor controls. All patients and controls expressed multip
Stable expression of the human immunodeficiency virus type 1 envelope glycoprotein in transfected L cells.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):1999-2009. Unique Identifier : AIDSLINE MED/93152273; Bird C; Gleeson PA; Ramsay A; Li P; McCluskey J; Department of Pathology and Immunology, Monash Medical School,; Prahran, Victoria, Australia.; An SV40-based expression vector was used to generate CD4-negative murine L cell lines which stably expressed the human immunodeficiency virus envelope glycoprotein (env). Despite the presence of abundant intracellular envelope glycoprotein, the expression of env gp120/41 was not detected on the cell surface. Pulse-cha
Strong association of simian immunodeficiency virus (SIVagm) envelope glycoprotein heterodimers: possible role in receptor-mediated activation.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):2011-20. Unique Identifier : AIDSLINE MED/93152274; Allan JS; Whitehead EM; Strout K; Short M; Kanda P; Hart TK; Bugelski PJ; Department of Virology and Immunology, Southwest Foundation for; Biomedical Research, San Antonio, TX 78228.; Soluble forms of a human cell-surface molecule expressed on T lymphocytes (CD4) neutralize diverse strains of both human (HIV) and simian (SIV) immunodeficiency viruses through the induction of envelope shedding and direct competition with cellular CD4 for virus binding. However, we have previously shown that sCD4 enh
Simian immunodeficiency virus (SIVsm) infection of cynomolgus monkeys: effects on follicular dendritic cells in lymphoid tissue.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):2021-30. Unique Identifier : AIDSLINE MED/93152275; Joling P; van Wichen DF; Parmentier HK; Biberfeld P; Bottiger D; Tschopp J; Rademakers LH; Schuurman HJ; Department of Pathology, University Hospital, Utrecht, The; Netherlands.; We studied follicles in sections of lymph nodes and spleen from cynomolgus monkeys (Macaca fascicularis) after infection with simian immunodeficiency virus (SIVsm), by (immuno)histology and (immunogold) electron microscopy. Also isolated follicular dendritic cells (FDC) were investigated. Histology showed ranged from
Changes in the reactivity and neutralizing activity of a type-specific neutralizing monoclonal antibody induced by interaction of soluble CD4 with gp120.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):2049-54. Unique Identifier : AIDSLINE MED/93152278; Maeda Y; Matsushita S; Hattori T; Murakami T; Takatsuki K; Second Department of Internal Medicine, Kumamoto University; Medical School, Japan.; Antibodies directed against the third hypervariable loop-domain (V3 loop) of human immunodeficiency virus type 1 (HIV-1) gp120 inhibit the infection by HIV-1 in a type-specific manner without interfering with the binding of gp120 to CD4. Previous studies demonstrated that soluble CD4 (sCD4) induced the dissociation of
Expression of human CD4 in transgenic mice does not confer sensitivity to human immunodeficiency virus infection.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):2063-71. Unique Identifier : AIDSLINE MED/93152280; Lores P; Boucher V; Mackay C; Pla M; Von Boehmer H; Jami J; Barre-Sinoussi F; Weill JC; Unite 257, Institut National de la Sante et de la Recherche; Medicale, Institut Cochin de Genetique Moleculaire, Paris,; France.; Transfection of the human CD4 molecule into mouse cells does not confer susceptibility to human immunodeficiency virus type 1 (HIV-1) infection. Expression of the human CD4 molecule in transgenic mice was seen to offer some new possibilities. However, transgenic mouse T cells expressing either the human CD4 receptor,
Trimethoprim, alone or in combination with sulphamethoxazole, decreases the renal excretion of zidovudine and its glucuronide.: Br J Clin Pharmacol. 1992 Dec;34(6):551-4. Unique Identifier : AIDSLINE MED/93152384; Chatton JY; Munafo A; Chave JP; Steinhauslin F; Roch-Ramel F; Glauser MP; Biollaz J; Departement de Medecine interne, Centre Hospitalier; Universitaire Vaudois, Switzerland.; Trimethoprim and trimethoprim-sulphamethoxazole (co-trimoxazole) are often prescribed in HIV patients treated with zidovudine. The pharmacokinetics of zidovudine, after a dose of 3 mg kg-1 by constant rate intravenous infusion over 1 h were evaluated in nine HIV patients in an open, randomized, three-phase crossover s
Think tuberculosis: 'No guarantees of a cure at this time' (continuing education credit).: Tenn Nurse. 1992 Dec;55(6):6-10. Unique Identifier : AIDSLINE MED/93152583; Murabito S; Oliver G
Use of birth control pills and condoms among 17-19-year-old adolescents in Norway: contraceptive versus protective behaviour?: AIDS Care. 1992;4(4):371-80. Unique Identifier : AIDSLINE MED/93152605; Traeen B; Lewin B; Sundet JM; National Institute of Alcohol and Drug Research, Oslo, Norway.; This article addresses the relationship between sexual risk behaviour and contraceptive behaviour, and considers whether adolescents who use condoms are practising birth control or STD protective behaviour. The material comprised a representative sample of 3000 Norwegians aged 17-19 years. Data were collected by anony
AIDS dementia-related psychosis: is there a window of vulnerability?: AIDS Care. 1992;4(4):381-7. Unique Identifier : AIDSLINE MED/93152606; el-Mallakh RS; Office on AIDS, Prince George's County Health Department,; Cheverly, Maryland.; Human immunodeficiency virus (HIV) frequently enters the central nervous system (CNS) soon after infection, and frequently produces a wide variety of neurologic, cognitive, and psychiatric complications. Although, the entire spectrum of psychiatric illnesses may be seen in individuals with HIV infection, most are prob
Differences in HIV-related knowledge and attitudes between Caucasian and 'Asian' men in Glasgow.: AIDS Care. 1992;4(4):389-93. Unique Identifier : AIDSLINE MED/93152607; Elliott L; Parida SK; Gruer L; HIV and Addictions Resource Centre, Ruchill Hospital, Glasgow,; United Kingdom.; There is little available information about the possible differences in HIV-related knowledge and attitudes between ethnic majority and minority groups. Questionnaires were completed by 490 Caucasian males and 243 males with origins in the Indian subcontinent ( Asian ) living in Glasgow. There were small differences b
Selling sex: female street prostitution and HIV risk behaviour in Glasgow.: AIDS Care. 1992;4(4):395-407. Unique Identifier : AIDSLINE MED/93152608; McKeganey N; Barnard M; Public Health Research Unit, University of Glasgow, United; Kingdom.; Female prostitutes have often been seen as a major source of HIV infection. In this paper we report on a study of HIV-related risk behaviour among street prostitutes in Glasgow. This paper is based on street interviews using a standardized schedule with 68 women. We focus on the extent of HIV testing amongst the women
Maintenance of open gay relationships: some strategies for protection against HIV.: AIDS Care. 1992;4(4):409-19. Unique Identifier : AIDSLINE MED/93152609; Hickson FC; Davies PM; Hunt AJ; Weatherburn P; McManus TJ; Coxon AP; South Bank University, London, UK.; The role of sexual exclusivity (monogamy) in relation to HIV, and the use of rule making in non-exclusive (open) relationships, are discussed. Data from interviews with 387 homosexually active men are presented. The most common sexual/relational configuration amongst these men is that of open relationships. Sexual non
The Edinburgh cohort of HIV positive drug users: who are they and who cares for them?: AIDS Care. 1992;4(4):421-4. Unique Identifier : AIDSLINE MED/93152610; Chiswick A; Egan V; Brettle RP; Goodwin GM; Regional Infectious Diseases Unit, City Hospital, Edinburgh, UK.; Between 1983 and 1984, it is estimated that over 1,000 injection drug users in Edinburgh were infected with HIV. The social and demographic characteristics of 300 HIV positive drug users attending a medical clinical between 1987 and 1991 have been recorded. Nearly all were unemployed, poorly educated and living in cou
Amsterdam AIDS Conference review.: AIDS Care. 1992;4(4):425-85. Unique Identifier : AIDSLINE MED/93152611
A statistical chronicle of tuberculosis in Canada: Part II. Risk today and control.: Health Rep. 1992;4(3):277-92. Unique Identifier : AIDSLINE MED/93152743; Brancker A; Enarson DA; Grzybowski S; Hershfield ES; Jeanes CW; Canadian Centre for Health Information, Statistics Canada.; This report marks over 50 years of publication by Statistics Canada of annual reports on Tuberculosis Statistics. These years have witnessed what has been described as a conquest of tuberculosis in Canada. To quote George Jasper Wherrett in the Miracle of the Empty Beds: One hundre
Tuberculosis and HIV infection association in a rural district of northern Uganda: epidemiological and clinical considerations.: Tuber Lung Dis. 1992 Oct;73(5):285-90. Unique Identifier : AIDSLINE MED/93152803; Migliori GB; Borghesi A; Adriko C; Manfrin V; Okware S; Naamara W; Bartoloni A; Neri M; Acocella G; Department of Pneumology, Tradate Medical Centre, Italy.; 59 (18.3%) of 323 patients with tuberculosis (TB) tested for HIV-1 antibody by ELISA technique (Wellcozyme) were seropositive. In the control group selected among the health personnel working in the Arua Hospital, 7.7% were found positive for HIV-1 antibody, thus showing a significantly lower prevalence compared with
I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding.: Mol Biol Cell. 1992 Dec;3(12):1339-52. Unique Identifier : AIDSLINE MED/93153017; Ganchi PA; Sun SC; Greene WC; Ballard DW; Gladstone Institute of Virology and Immunology, University of; California, San Francisco.; The active nuclear form of the NF-kappa B transcription factor complex is composed of two DNA binding subunits, NF-kappa B p65 and NF-kappa B p50, both of which share extensive N-terminal sequence homology with the v-rel oncogene product. The NF-kappa B p65 subunit provides the transactivation activity in this complex
Sex survey gives information on HIV risk [news]: BMJ. 1992 Dec 12;305(6867):1452-3. Unique Identifier : AIDSLINE MED/93153255; Handysides S
Life insurance and HIV antibody testing [letter]: BMJ. 1992 Dec 12;305(6867):1497. Unique Identifier : AIDSLINE MED/93153269; Ogle JL
Life insurance and HIV antibody testing [letter]: BMJ. 1992 Dec 12;305(6867):1497-8. Unique Identifier : AIDSLINE MED/93153272; Tamin J
Life insurance and HIV antibody testing [letter]: BMJ. 1992 Dec 12;305(6867):1498. Unique Identifier : AIDSLINE MED/93153274; Evans BA
A commentary on strategies for AIDS prevention from the British perspective.: Clin Nurs Res. 1992 Feb;1(1):25-7. Unique Identifier : AIDSLINE MED/93153385; MacDonald SJ; The commentary review similarities between the American and the European perspective of the HIV spread, with particular emphasis on the British mode of transmission among women. Social perceptions of the female role are seen as contributing to the difficulties experienced by British women who are HIV positive. Althoug
Strategies for AIDS prevention: leadership training and peer counseling for high-risk African-American women in the drug user community.: Clin Nurs Res. 1992 Feb;1(1):9-24. Unique Identifier : AIDSLINE MED/93153393; Harris RM; Kavanagh KH; Hetherington SE; Scott DE; A culturally congruent training program to promote HIV risk-reduction behaviors was implemented in a convenient sample of 9 African-American women in an urban methadone treatment program. At each of eight peer counseling and leadership training (PCLT) program sessions, the transmission and prevention of AIDS were disc
[Demonstration of a protector effect of interleukin-1 against hematologic toxicity of azidothymidine (AZT)]: C R Seances Soc Biol Fil. 1992;186(3):206-14. Unique Identifier : AIDSLINE MED/93153673; Arock M; Dedenon A; Damais C; Averlant G; Guillosson JJ; Laboratoire d'Hematologie, Faculte de Pharmacie, Paris.; 3 -azido-3 -deoxythymidine (Azidothymidine or AZT ) has attained wide critical utility in the treatment of acquired immunodeficiency syndrome (AIDS). Unfortunately, treatment with AZT is associated with the development of severe hematopoietic toxicity.
Tuberculosis in HIV positive patients in South Africa: a comparative radiological study with HIV negative patients.: Clin Radiol. 1992 Dec;46(6):387-90. Unique Identifier : AIDSLINE MED/93153929; Saks AM; Posner R; Department of Radiology, Coronation Hospital, Johannesburg, South; Africa.; The radiological appearances of active tuberculosis in human immunodeficiency virus (HIV) positive patients was reviewed. A study group of 61 Black HIV positive patients and a control group of 50 Black HIV negative patients were analysed. The chest radiographs of the HIV seropositive group showed a significantly highe
Case report: pneumatosis intestinalis occurring in association with cryptosporidiosis and HIV infection.: Clin Radiol. 1992 Dec;46(6):410-1. Unique Identifier : AIDSLINE MED/93153935; Collins CD; Blanshard C; Cramp M; Gazzard B; Gleeson JA; Department of Radiology, Westminster Hospital, London.; We report a case of pneumatosis intestinalis (PI) occurring in association with cryptosporidiosis in a patient documented as being HIV-seropositive. Chest and abdominal radiographs taken 2 months previously were normal and the patient did not have any evidence of gastrointestinal infection at that time. The case was c
[Efficacy of paromomycin sulfate (Humagel) in an AIDS infected patient with intestinal cryptosporidiosis (letter)]: Gastroenterol Clin Biol. 1992;16(12):1010-1. Unique Identifier : AIDSLINE MED/93154547; Hammel P; Rogeaux O; Diouf ML; Gouyon B; Ruszniewski P; Bernades P
The in-vitro bactericidal activities of combinations of antimicrobial agents against clinical isolates of Mycobacterium avium-intracellulare.: J Antimicrob Chemother. 1992 Nov;30(5):643-50. Unique Identifier : AIDSLINE MED/93154940; Kent RJ; Bakhtiar M; Shanson DC; Department of Medical Microbiology, Charing Cross and Westminster; Medical School, London, UK.; The in-vitro activities of five antimicrobial agents (rifabutin, clarithromycin, ethambutol, ciprofloxacin and amikacin), alone and in combination, were evaluated against 21 strains of Mycobacterium avium-intracellulare isolated from patients with AIDS. The combined activities of these agents were studied on solid med
A new approach to estimating AIDS incubation times: results in homosexual infected men.: J Epidemiol Community Health. 1992 Dec;46(6):582-6. Unique Identifier : AIDSLINE MED/93155609; Chevret S; Costagliola D; Lefrere JJ; Valleron AJ; Department de Biostatistique et Information Medicale, Hopital; Saint-Louis, Paris, France.; STUDY OBJECTIVE--The aim was to develop a new approach for estimating the incubation period of acquired immunodeficiency syndrome (AIDS), based on age distributions. DESIGN--Incubation period was expressed as the difference between age at time of diagnosis and age at time of contamination. Assuming independence betwee
Acute effects of a nucleoside analog dideoxyinosine (DDI) on the pancreas.: J Surg Res. 1992 Dec;53(6):610-4. Unique Identifier : AIDSLINE MED/93156265; Nordback IH; Olson JL; Chaisson RE; Cameron JL; Department of Surgery, Johns Hopkins University, Baltimore,; Maryland 21205.; Dideoxyinosine (DDI, Videx ) is a recently developed nucleoside analog with activity against the human immunodeficiency virus. A significant number of patients with AIDS or AIDS-related complex treated with DDI have developed acute pancreatitis. This s
[Cryptococcosis caused by Cryptococcus neoformans var. Gattii. A case associated with acquired immunodeficiency syndrome (AIDS) in Kinshasa, Zaire]: Med Trop (Mars). 1992 Oct-Dec;52(4):435-8. Unique Identifier : AIDSLINE MED/93156598; Muyembe Tamfum JJ; Mupapa Kibadi D; Nganda L; Ngwala-Bikindu D; Kuezina T; Kela-We I; Vandepitte J; Departement de Microbiologie, Universite de Kinshasa, Zaire.; Since the introduction of AIDS, the biovar neoformans of Cryptococcus neoformans has replaced the biovar gattii as the predominant agent of cryptococcal meningitis in Kinshasa and in other tropical areas. That this is not an absolute rule is demonstrated by the present case of a HIV-positive patient, observed at the K
[Bacteremia caused by non-typhoid Salmonellas during an infection by the human immunodeficiency virus (HIV) in the African adult]: Med Trop (Mars). 1992 Oct-Dec;52(4):447-50. Unique Identifier : AIDSLINE MED/93156601; Aubry P; Niyongabo T; Nizigiye J; Muhirwa G; Kamanfu G; Ndahiragije A; Kinigi J; Faculte de Medecine, Centre Hospitalier Universitaire Kamenge; Bujumbura, Burundi.; Infection caused by non-typhous Salmonellae during the course of HIV infection is known since 1983. The authors report on 103 bacteremiae of this type found in one year. Diagnosis has been based on hemocultures. 86 patients out of 103 were HIV+. All of them were febrile. 67 suffered from digestive disorders, 33 with d
Extensive dermatophytoses caused by Trichophyton mentagrophytes and Microsporum canis in a patient with AIDS.: Mycopathologia. 1992 Dec;120(3):143-6. Unique Identifier : AIDSLINE MED/93156792; Lowinger-Seoane M; Torres-Rodriguez JM; Madrenys-Brunet N; Aregall-Fuste S; Saballs P; Department of Microbiology, Universitat Autonoma de Barcelona,; Spain.; Retrospective studies have shown the occurrence of episodes of deep or superficial fungal infections in 58 to 81% of HIV/AIDS patients as a result of impairment of cell immunity. We describe a case of disseminated cutaneous dermatophytoses caused by Trichophyton mentagrophytes and Microsporum canis in a patients with
[Isolation of Toxoplasma gondii by cellular culture in HIV infected patients]: Presse Med. 1992 Nov 21;21(39):1853-6. Unique Identifier : AIDSLINE MED/93157279; Derouin F; Garin YJ; Laboratoire de Parasitologie-Mycologie, Hopital Saint-Louis,; Paris.; Nine hundred and eight biological samples obtained from HIV-infected patients were examined for Toxoplasma gondii by a tissue culture method. Sixty-two isolations of Toxoplasma gondii were made in 43 patients. Fourteen isolations were made from tissue biopsies (brain 4, striated muscle 2, liver 1), bone marrow aspirat
[Transmission of HIV infection in Madagascar. Risk factors of contamination (letter)]: Presse Med. 1992 Nov 21;21(39):1871-2. Unique Identifier : AIDSLINE MED/93157285; Rasamindrakotroka AJ; Kirsch T; Rarivoharilala E; Andriamahenina R; Rakotomanga S
[Pulmonary tuberculosis and other mycobacterial infections in patients with AIDS]: Radiol Med (Torino). 1992 Dec;84(6):744-9. Unique Identifier : AIDSLINE MED/93157660; Pignatelli V; Savalli E; Perri G; Russo R; Bagnolesi A; Savino A; II Servizio di Radiodiagnostica, USL n. 12 Pisa.; Nowadays, the acquired immune deficiency syndrome (AIDS) is most certainly the major cause of the increased incidence of tuberculosis (TBC). A total of 138 patients (pts) with AIDS were referred to the Department of Infectious Diseases of the Hospital of Pisa, 1990-1991; 14 of them (10.1%) presented pulmonary TBC. In
[An in-vivo and in-vitro study of phagocyte migration in patients with AIDS]: Recenti Prog Med. 1992 Dec;83(12):680-4. Unique Identifier : AIDSLINE MED/93157701; Pasotti D; Mazzone A; Ricevuti G; Istituto Superiore di Sanita, Roma.; Polymorphonuclear leukocytes (PMN), are considered the first line of host defense. The PMN defects were related with an increase susceptibility to infections. We studied the neutrophil chemotactic function in 20 patients suffering from AIDS. The results of in vivo study demonstrated the decrease of chemotactic activit
[Isosporiasis and sarcocystosis. The current findings]: Recenti Prog Med. 1992 Dec;83(12):719-25. Unique Identifier : AIDSLINE MED/93157709; Dionisio D; Santucci M; Comin CE; Di Lollo S; Orsi A; Gabbrielli M; Milo D; Rogasi PG; Meli M; Vigano S; Divisione di Malattie infettive, Policlinico di Careggi, Firenze.; A review on infections by Isospora belli and Sarcocystis spp. both in healthy and in AIDS patients is done on the basis of literature and personal data. In this view a special focus is made on isospora belli infection in AIDS because of its high recurrence after successful attack therapy. Consequently the most recent
Diagnosis of Pneumocystis carinii pneumonia in HIV antibody positive patients by simple outpatient assessments [see comments]: Thorax. 1992 Dec;47(12):1005-9. Unique Identifier : AIDSLINE MED/93157934; Smith DE; Forbes A; Davies S; Barton SE; Gazzard BG; HIV/GUM Department, Kobler Centre, London.; BACKGROUND: As increasing numbers of patients with immunosuppression induced by the human immunodeficiency virus (HIV) present with respiratory symptoms it is important to differentiate Pneumocystis carinii pneumonia from other chest diseases rapidly and start treatment early. The management of pneumocystis pneumonia
Recent developments in the management of the pulmonary complications of HIV disease [letter; comment]: Thorax. 1992 Dec;47(12):1084. Unique Identifier : AIDSLINE MED/93157953; Davies PD
Lymphocyte and lymphocyte subset numbers in blood and bronchoalveolar lavage and pleural fluid in various forms of human pulmonary tuberculosis [letter; comment]: Thorax. 1992 Dec;47(12):1085-6. Unique Identifier : AIDSLINE MED/93157954; Grange JM; Stanford JL; Beck JS
Nuclear and mitochondrial changes of muscle fibers in AIDS after treatment with high doses of zidovudine.: Acta Neuropathol (Berl). 1992;85(1):39-47. Unique Identifier : AIDSLINE MED/93158329; Schroder JM; Bertram M; Schnabel R; Pfaff U; Institut fur Neuropathologie, Klinikum der; Rheinisch-Westfalischen Technischen Hochschule, Aachen, Federal; Republic of Germany.; Zidovudine (formerly azidothymidine) is a potent inhibitor of the human immunodeficiency virus (HIV) reverse transcriptase and represents the first approved drug showing clinical efficacy in HIV-associated diseases. However, considerable toxicity causing macrocytic anemia, neutropenia, and myopathy has been reported,
One pharmacist's work for AIDS patients.: Am Pharm. 1992 Dec;NS32(12):45-7. Unique Identifier : AIDSLINE MED/93158507; Martin S
[Findings of bile duct ultrasonography in 100 patients with AIDS in black Africa]: Ann Gastroenterol Hepatol (Paris). 1992 Nov-Dec;28(6-7):253-7. Unique Identifier : AIDSLINE MED/93159097; Aubry P; Nintije J; Reynaud JP; Ndabaneze E; Mucikire E; Departement de Medecine Interne, Centre Hospitalo Universitaire; de Kamenge, Bujumbura, Burundi.; A systematic study of bile ducts by abdominal echotomography on 100 African patients affected by AIDS disease has showed 11 bile ducts abnormalities (7 alithiasic cholecystitis and 6 inflammatory cholangitis, associated in 2 cases). The patients studies showed several associated infections, particularly a pulmonary tu
Diffuse infiltrative lymphocytosis syndrome in children and adults infected with HIV-1: a model of rheumatic illness caused by acquired viral infection.: Am J Reprod Immunol. 1992 Oct-Dec;28(3-4):247-50. Unique Identifier : AIDSLINE MED/93159610; Itescu S; Department of Pediatrics, Columbia University, College of; Physicians and Surgeons, New York, NY 10032.; Certain maternal/infant pairs, as well as other high-risk adults, develop a host-response HIV-1 infection characterized by circulating and tissue infiltrative CD8 T-cell lymphocytosis, termed Diffuse Infiltrative Lymphocytosis Syndrome (DILS). DILS primarily occurs in the salivary glands, lungs, renal interstitium, an
Prospective study with combined low-dose chemotherapy and zidovudine in 37 patients with poor-prognosis AIDS-related non-Hodgkin's lymphoma. French-Italian Cooperative Study Group.: Ann Oncol. 1992 Dec;3(10):843-7. Unique Identifier : AIDSLINE MED/93160075; Tirelli U; Errante D; Oksenhendler E; Spina M; Vaccher E; Serraino D; Gastaldi R; Repetto L; Rizzardini G; Carbone A; et al; Division of Medical Oncology, Centro di Riferimento Oncologico; (CRO), Aviano, Italy.; The French-Italian Cooperative Study Group included patients with poor-prognosis AIDS-related non-Hodgkin s lymphoma (NHL), defined as those with performance status (PS) > or = 3 and/or opportunistic infections (OI), in a prospective study with a 50% reduced-dose combination chemot
Syphilis: new diagnostic directions [editorial]: Int J STD AIDS. 1992 Nov-Dec;3(6):391-413. Unique Identifier : AIDSLINE MED/93160301; Young H
The role of maternal syphilis, gonorrhoea and HIV-1 infections in spontaneous abortion.: Int J STD AIDS. 1992 Nov-Dec;3(6):418-22. Unique Identifier : AIDSLINE MED/93160303; Temmerman M; Lopita MI; Sanghvi HC; Sinei SK; Plummer FA; Piot P; Department of Medical Microbiology, University of Nairobi, Kenya.; The role of the human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs) as risk factor for spontaneous abortion was investigated in a case-control study in Nairobi, Kenya . Cases (n = 195) were women admitted with clinical signs and symptoms of spontaneous a
Urethritis due to Neisseria meningitidis in a London genitourinary medicine clinic population.: Int J STD AIDS. 1992 Nov-Dec;3(6):423-5. Unique Identifier : AIDSLINE MED/93160304; Maini M; French P; Prince M; Bingham JS; Department of Genitourinary Medicine, Middlesex Hospital, London,; UK.; A retrospective study was performed in a department of genitourinary medicine to determine the prevalence and clinical features of urethral and cervical infection with Neisseria meningitidis among patients being screened for sexually transmitted diseases. During the 28 month period of the study 11 isolates (from 10 pa
The impact of HIV disease on an Irish prison population.: Int J STD AIDS. 1992 Nov-Dec;3(6):426-9. Unique Identifier : AIDSLINE MED/93160305; Murphy M; Gaffney K; Carey O; Dooley E; Mulcahy F; Department of Genitourinary Medicine, St James's Hospital,; Dublin, Ireland.; Between January 1987 and January 1991, 168 known HIV-infected prisoners have been incarcerated in Dublin s Mountjoy prison. This figure constitutes 16.6% of the total HIV-infected population in the Republic of Ireland over the same
Gonorrhoea: signs, symptoms and serogroups.: Int J STD AIDS. 1992 Nov-Dec;3(6):430-3. Unique Identifier : AIDSLINE MED/93160306; Horner PJ; Coker RJ; Turner A; Shafi MS; Murphy SM; Patrick Clements Clinic, Central Middlesex Hospital, London, UK.; Over 19 weeks, 104 male patients attending a genitourinary medicine clinic with gonococcal urethritis were asked to complete a questionnaire detailing symptoms. Sixty-seven questionnaires were duly completed. The examining nurse documented signs. Ninety-one isolates of Neisseria gonorrhoeae were serogrouped and auxoty
Prevalence of urogenital Chlamydia trachomatis infection in El Salvador. II. Gynaecology outpatients.: Int J STD AIDS. 1992 Nov-Dec;3(6):434-6. Unique Identifier : AIDSLINE MED/93160307; Canas Posada AB; Jonasson J; de Linares L; Bygdeman S; Department of Microbiology, Faculty of Medicine, University of El; Salvador.; The prevalence of urogenital infection caused by Chlamydia trachomatis was examined in 100 non-pregnant women with cervicitis, and 100 healthy women, in San Salvador City, El Salvador . Pharmacia Chlamydia EIA test was used for the detection of chlamydial antigen in urethral and
Sexual behaviour amongst travellers: a study of genitourinary medicine clinic attenders.: Int J STD AIDS. 1992 Nov-Dec;3(6):437-8. Unique Identifier : AIDSLINE MED/93160308; Daniels DG; Kell P; Nelson MR; Barton SE; Department of HIV, St Stephen's Clinic London, UK.; Two hundred and fifty attendees at two London genitourinary medicine clinics were asked to complete an anonymous self-administered questionnaire, enquiring about sexual behaviour whilst abroad. Two hundred and forty-three questionnaires were evaluable. In the study group there were 116 women, and 127 men (62 heterosex
Treatment of anogenital warts in genitourinary clinics in England and Wales.: Int J STD AIDS. 1992 Nov-Dec;3(6):439-41. Unique Identifier : AIDSLINE MED/93160309; Wardropper A; Woolley P; Manchester Royal Infirmary, UK.; A questionnaire on the treatment of anogenital warts was sent to 150 consultants in genitourinary medicine, 78 (52%) were returned completed. A wide range of treatments were used; podophyllin was the commonest first line treatment of multiple penile (60.3%), perianal (57.7%) and vulval (61.5%) warts. Cryotherapy was a
Atypical presentations of herpes simplex virus infection.: Int J STD AIDS. 1992 Nov-Dec;3(6):442-4. Unique Identifier : AIDSLINE MED/93160310; Dhar J; Carey PB; Alawattegama AB; University Department of Genitourinary Medicine, Royal Liverpool; Hospital, UK.
An inguinal bubo caused by Mycobacterium chelonae abscessus.: Int J STD AIDS. 1992 Nov-Dec;3(6):447. Unique Identifier : AIDSLINE MED/93160312; Fisk P; Department of Genitourinary Medicine, Leicester Royal Infirmary,; UK.
Survey of attitudes of a sexually transmissible diseases clinic staff to the proposed creation at that clinic of a comprehensive sexual health centre [letter]: Int J STD AIDS. 1992 Nov-Dec;3(6):449-50. Unique Identifier : AIDSLINE MED/93160314; Fong N; Evans DT
Aids literature index.: Int J STD AIDS. 1992 Nov-Dec;3(6):455-70. Unique Identifier : AIDSLINE MED/93160316
Activation-induced apoptosis in lymphoid systems.: Semin Immunol. 1992 Dec;4(6):379-88. Unique Identifier : AIDSLINE MED/93160468; Green DR; Bissonnette RP; Glynn JM; Shi Y; La Jolla Institute for Allergy and Immunology, CA 92037.; Lymphocytes become activated when antigen receptors on the cell surface are cross-linked, or when they are exposed to agents that mimic this signal. Although such activation is usually associated with the production of immune mediators (e.g. antibodies, cytokines) and entry into the cell cycle, it can alternatively le
Hemophilic blood cyst--a case report.: Chin Med Sci J. 1992 Sep;7(3):181-3. Unique Identifier : AIDSLINE MED/93160496; Tang D; Zhou S; First Affiliated Hospital, Zhejing Medical University, Hangzhou.; We report a case of hemophilic blood cyst in a patient with human immunodeficiency virus (HIV) infection. The pathogenesis, diagnosis and treatment are discussed, and neither inflammatory changes nor pathological cells were seen in the numerous histological sections obtained surgically.
Tuberculosis [letter]: R I Med. 1992 Dec;75(12):558. Unique Identifier : AIDSLINE MED/93160574; Rakatansky H
Hashimoto's thyroiditis in HTLV-I carriers.: Intern Med. 1992 Oct;31(10):1213-6. Unique Identifier : AIDSLINE MED/93160615; Kawai H; Saito M; Takagi M; Tsuchihashi T; Arii Y; Kondo A; Iwasa M; Hirose T; Hizawa K; Saito S; First Department of Internal Medicine, School of Medicine,; University of Tokushima, Japan.; We describe two HTLV-I virus carriers who have biopsy-proven Hashimoto s thyroiditis. The first patient, a 64-year-old female, has had goiter and hypothyroidism since the age of 56. The second patient, a 66-year-old male, developed hyperthyroidism and goiter at the age of 44, but at present he is hypothyroid. Both pat
[Drug-assisted treatment of substance dependence (Drug and Alcohol Symposium, Basel 1992)]: Gesundheitswesen. 1992 Nov;54(11):673-7. Unique Identifier : AIDSLINE MED/93160670; Gostomzyk JG; Gesundheitsamt Augsburg.; The report on the symposium is an interim account of the treatment of drug addiction in Switzerland . The spread of drugs could not be halted by prohibition. The ideal of a drug-free society does not seem to be translatable into reality. Hence, it is unrealistic to set up conti
Sexuality and HIV/AIDS.: Nurs Prax N Z. 1992 Nov;7(3):11-6. Unique Identifier : AIDSLINE MED/93160742; Pulotu-Endemann K
[Experiences with pregnancies in HIV-positive females]: Gynakol Geburtshilfliche Rundsch. 1992;32 Suppl 1:88-9. Unique Identifier : AIDSLINE MED/93160817; Waitz-Penz A; Sailer M; Schrocksnadel H; Kirchler H; Mayr P; Neugebauer H; Dapunt O; Univers.-Klinik f. Frauenheilk, Innsbruck.
A pilot study of steroid withdrawal followed by oral acyclovir in the treatment of chronic type B hepatitis.: Clin Invest Med. 1992 Dec;15(6):506-12. Unique Identifier : AIDSLINE MED/93161608; Minuk GY; German GB; Bernstein C; Benarroch A; Gauthier T; Sekla L; Department of Medicine, University of Manitoba Liver Diseases; Unit, Health Sciences Centre, Winnipeg.; Ten patients with chronic type B hepatitis were treated for four weeks with a rapidly tapered dose of oral prednisone (initial dose, 40 mg/d) followed by two weeks of no therapy followed by four weeks of oral acyclovir (600 mg/d). Liver biochemistry, HBsAg, HBeAg, DNA-polymerase
Legal issues in transfusion medicine. Is blood banking a medical profession?: Clin Lab Med. 1992 Dec;12(4):819-33. Unique Identifier : AIDSLINE MED/93161691; Kelly C; Barber JP; American Association of Blood Banks, Bethesda, Maryland.; In legislation concerning the transfusion of AIDS, the issue of whether blood banking is a profession has become extremely important. The status of blood banking determines how blood center actions will be judged and what liability rules will be applied. The issue was recently hotly argued in the high courts of Colora
Health beliefs and promotion of HIV-preventive intentions among teenagers: a Scottish perspective.: Health Psychol. 1992;11(6):363-70. Unique Identifier : AIDSLINE MED/93162031; Abraham C; Sheeran P; Spears R; Abrams D; Department of Epidemiology and Public Health, University of; Dundee, Ninewells Hospital and Medical School, Scotland.; Beliefs concerning the spread of the human immunodeficiency virus (HIV) and preventive behaviors were examined in a sample of 351 sexually active Scottish teenagers. A postal questionnaire, including measures of variables specified by the health belief model (HBM) and preventive intentions, was employed. The relation
Would taming the T-cell quieten the eye? [editorial]: Eye. 1992;6 ( Pt 5):vii. Unique Identifier : AIDSLINE MED/93162218; Lightman S
Serum antibodies to HIV-1 in recombinant vaccinia virus recipients boosted with purified recombinant gp160. NIAID AIDS Vaccine Clinical Trials Network.: J Clin Immunol. 1992 Nov;12(6):429-39. Unique Identifier : AIDSLINE MED/93163242; Montefiori DC; Graham BS; Kliks S; Wright PF; Department of Pathology, Vanderbilt University Medical School,; Nashville, Tennessee 37232.; Serum antibody responses were studied in detail in four vaccinia-naive volunteers in a phase I trial evaluating primary vaccination with a recombinant vaccinia virus expressing the HIV-1 gp160 envelope glycoprotein (HIVAC-1e, Oncogen/ Bristol-Myers Squibb ), followed by booster immunizat
Problems of AIDS in developing countries [editorial] [see comments]: J Indian Med Assoc. 1992 Oct;90(10):254-6. Unique Identifier : AIDSLINE MED/93163589; Dutta GP
Fc gamma receptors in cancer and infectious disease.: Immunol Res. 1992;11(3-4):203-16. Unique Identifier : AIDSLINE MED/93163666; Fanger MW; Erbe DV; Department of Microbiology, Dartmouth Medical School, Lebanon,; N.H. 03756.; Through interaction with antibody, IgG Fc receptors provide an interface between specific humoral immunity and Fc gamma R-bearing host cells. Fc gamma R trigger such diverse functions as immune complex clearance, phagocytosis of opsonized pathogens, reactive oxygen intermediate and enzyme secretion, and antibody-depen
Nested polymerase chain reaction for detection of human immunodeficiency virus type 1 DNA in clinical specimens.: J Med Virol. 1992 Nov;38(3):172-4. Unique Identifier : AIDSLINE MED/93163771; Zazzi M; Romano L; Brasini A; Valensin PE; Department of Molecular Biology, University of Siena, Italy.; A highly sensitive two-step polymerase chain reaction (PCR) method was evaluated for detection of human immunodeficiency virus type 1 (HIV-1) DNA in clinical specimens. The product resulting from the first amplification reaction is used as the template for the second PCR with an internal (nested) primer pair. Even whe
Persistent delta antigenaemia in chronic delta hepatitis and its relation with human immunodeficiency virus infection.: J Med Virol. 1992 Nov;38(3):191-4. Unique Identifier : AIDSLINE MED/93163774; Roingeard P; Dubois F; Marcellin P; Bernuau J; Bonduelle S; Benhamou JP; Goudeau A; Laboratoire de Virologie, URA CNRS 1334, Hopital Bretonneau,; Tours, France.; The prevalence of persistent hepatitis delta (HD) antigenaemia and associated factors in patients with chronic infection with the hepatitis delta virus (HDV) were investigated. Among 157 consecutive patients known to be carriers of hepatitis B surface antigen (HBsAg), 36 (23%) had one serum marker of HDV infection (an
AIDS patients with bacterial lower respiratory tract infections: treatment with ofloxacin versus sulbactam-ampicillin.: J Chemother. 1992 Dec;4(6):376-80. Unique Identifier : AIDSLINE MED/93163839; De Simone C; Trinchieri V; Tzantzoglou S; Famularo G; Moretti S; Delia S; Dept. Exp. Medicine, University of L'Aquila, Italy.; In this open-label, randomized, parallel-groups study the Authors compare the parenteral administration of a beta-lactamase inhibitor associated with a semisynthetic penicillin (sulbactam-ampicillin) with the oral administration of a 3rd-generation quinolone (ofloxacin), in 20 HIV-infected subjects suffering from lowe
Fluconazole and ketoconazole in the treatment of oral and esophageal candidiasis in AIDS patients.: J Chemother. 1992 Dec;4(6):381-6. Unique Identifier : AIDSLINE MED/93163840; Barchiesi F; Giacometti A; Arzeni D; Branchesi P; Crescenzi G; Ancarani F; Scalise G; Institute of Infectious Diseases, University of Ancona, Italy.; In our study 77 AIDS patients suffering from oral and/or esophageal candidiasis were evaluated: 38 received fluconazole, 39 ketoconazole. We analyzed the rates of clinical and mycological responses, relapses and toxicities. In vitro susceptibility tests for both antifungal drugs were performed by evaluating their Mini
Confidentiality in the age of AIDS.: J Reprod Med. 1992 Dec;37(12):969-72. Unique Identifier : AIDSLINE MED/93164130; Benrubi GI; Department of Obstetrics and Gynecology, University Medical; Center, University of Florida Health Science Center,; Jacksonville.; Confidentiality is a fundamental rule of medicine and has been specifically defined in many codes of medical ethics. A changing clinical environment both because of diseases such as AIDS, which were not anticipated when these clinical codes were created, and because of the changing relationship between the physician,
[Chronic fatigue syndrome--symptoms, signs, laboratory tests, and prognosis]: Nippon Rinsho. 1992 Nov;50(11):2586-90. Unique Identifier : AIDSLINE MED/93164418; Kanayama Y; Second Department of Internal Medicine, Osaka University Medical; School.; Chronic fatigue syndrome (CFS) is an undefined clinical problem and is perceived as a complex of multiple symptomatology with an unexplained persistent fatigue. Major symptoms include fatigue lasting for more than 6 months, low-grade fever, moderate lymphadenopathy, muscle and joint pain, and various psychological pre
Suppression of cell-mediated immunity by street rabies virus infection.: Microbiol Immunol. 1992;36(12):1277-90. Unique Identifier : AIDSLINE MED/93164898; Hirai K; Kawano H; Mifune K; Fujii H; Nishizono A; Shichijo A; Mannen K; Department of Microbiology, Oita Medical University, Japan.; An attempt to define a severe suppression of cell-mediated immunity by street rabies virus infection was undertaken by using the mice lethally and peripherally infected with a street rabies virus (1088 strain). The cell-mediated cytotoxic (CMC) activity of the spleen cells from those mice once slightly increased until
[Update oncology '92. The age of meta-analysis]: Med Klin. 1992 Dec 15;87(12):646-60. Unique Identifier : AIDSLINE MED/93164960; Schwamborn J; Pfreundschuh M; Medizinische Klinik und Poliklinik, Universitat des Saarlandes,; Homburg, Saar.
Susceptibility of yeast isolates from defined German patient groups to 5-fluorocytosine.: Mycoses. 1992 Jul-Aug;35(7-8):163-71. Unique Identifier : AIDSLINE MED/93165061; Weber S; Polak A; E Hoffmann-La Roche Ltd. Basel, Switzerland.; Susceptibility and development of resistance to 5-fluorocytosine (5-FC) in Candida strains isolated from defined German groups of probands was investigated. 5-FC susceptibility was determined in a microdilution assay in yeast nitrogen base after 24 h of incubation at 37 degrees C. The range of 5-FC concentration inves
Quantitative assessment of the efficacy of oral ketoconazole for oral candidosis in HIV-infected patients.: Mycoses. 1992 Jul-Aug;35(7-8):173-6. Unique Identifier : AIDSLINE MED/93165062; Korting HC; Blecher P; Froschl M; Braun-Falco O; Department of Dermatology, Ludwig-Maximilians University, Munich,; Germany.; Fifteen male patients with manifest oral candidosis due to Candida albicans, suffering from AIDS-related complex (ARC) or full-blown AIDS, were investigated both clinically and microbiologically before and about 1 and 4 weeks after 7 to 10 days of treatment with 200 mg ketoconazole p.o. per day. Candida albicans was q
Tuberculosis in patients infected with human immunodeficiency virus 1. A retrospective multicentre study of 123 cases in France. The Groupe des Infectiologues du Sud de la France.: Q J Med. 1992 Oct;85(306):719-30. Unique Identifier : AIDSLINE MED/93165887; Dupon M; Ragnaud JM; Service de Maladies Infectieuses et Medecine Interne, Hopital; Pellegrin, Bordeaux, France.; In order to study the epidemiological, clinical, and progressive characteristics of TB in HIV-infected individuals, a retrospective study was conducted in nine infectious disease centres of university hospitals located in the southern half of France . Among the 5730 HIV-seropositive
[Computer simulation of the 10-year outcome of a cohort of heroin addicts in Ile-de-France]: Rev Epidemiol Sante Publique. 1992;40(6):454-9. Unique Identifier : AIDSLINE MED/93165981; Charpak Y; Bejanin F; EVAL (bureau d'etudes en evaluation medicale et sante; publique, Paris, France.; The aim of this study is to develop a computer simulation model to describe imaginary cohorts of heroin users in the Ile de France (greater Paris) region. Because of the lack of well-designed cohort studies in France, this model is based on epidemiological data found in various dif
[Sarcoidosis and leukemia/T-cell lymphoma associated with HTLV-1 virus infection in adults (apropos of a case)]: Rev Med Interne. 1992 Jul-Aug;13(4):299-301. Unique Identifier : AIDSLINE MED/93166089; Panelatti G; Plumelle Y; Arfi S; Pascaline N; Caplanne D; Jean-Baptiste G; Service de Medecine Interne, CHRU, Fort de France.; The HTLV-1 virus causes a disturbance of the immune system, the evaluation of which is often difficult. We report a case of sarcoidosis in a 49 year old woman of Martinique as evidenced by bilateral hilar adenopathy, hypercalcaemia,
The AIDS epidemic in Tanzania: rate of spread of HIV in blood donors and pregnant women in Dar es Salaam.: Scand J Infect Dis. 1992;24(6):701-6. Unique Identifier : AIDSLINE MED/93166221; Haukenes G; Shao J; Mhalu F; Nome S; Sam NE; Department of Microbiology, Gade Institute, University of Bergen,; Norway.; The prevalence of antibodies to HIV in population groups in Dar es Salaam, Tanzania has been monitored from late 1984 through 1991. In the pregnant women and blood donors the doubling time was about 2 years. If, however, the doubling time is calculated from reported cases of AIDS
Sexually acquired HIV infections: an analysis of epidemiological data concerning cases reported in Sweden 1988-90.: Scand J Infect Dis. 1992;24(6):707-13. Unique Identifier : AIDSLINE MED/93166222; Blaxhult A; Eriksson G; Bottiger M; Lidman K; Department of Epidemiology, National Bacteriological Laboratory,; Stockholm, Sweden.; 536 Swedish residents who during the years 1988-90 were reported as having contracted HIV through sexual contacts were asked about circumstances regarding the transmission. Answers were received in 411 (76.7%) of the cases (285 homosexual men, 68 heterosexual men and 58 heterosexual women). In 282 (69%) of the cases t
A six-year follow-up of HIV seroprevalence among 300 intravenous drug users in Stockholm.: Scand J Infect Dis. 1992;24(6):715-23. Unique Identifier : AIDSLINE MED/93166223; Blaxhult A; Janzon R; Bottiger M; Annell A; Gabrielsson G; Rantala J; Wejderma A; Department of Epidemiology, National Bacteriological Laboratory,; Stockholm, Sweden.; As HIV tests became available in 1984, 300 intravenous drug users (IVDUs) admitted to treatment centres in Stockholm were tested and asked questions regarding their drug use and other risk factors with regard to HIV. At this initial testing, 33 persons (11.0%) were seropositive. Among the 79 heroin users, 28 (35.4%) w
Clinical and immunological follow-up of previously hospitalized HIV-2 seropositive patients in Bissau, Guinea-Bissau.: Scand J Infect Dis. 1992;24(6):725-31. Unique Identifier : AIDSLINE MED/93166224; Naucler A; Albino P; Andersson S; Paolo da Silva A; Linder H; Andreasson PA; Biberfeld G; Department of Immunology, National Bacteriological Laboratory,; Stockholm, Sweden.; A follow-up study was done in Bissau on 113 HIV-2 seropositive patients and 97 HIV-2 seronegative patients 3-15 months after hospitalization. Follow-up totalled 63.5 person years for seropositive patients and 62 for seronegative patients. The mortality during the follow-up period was 43.3% among the seropositive patie
Multiresistant Shigella species from African AIDS patients: antibacterial resistance patterns and application of the E-test for determination of minimum inhibitory concentration.: Scand J Infect Dis. 1992;24(6):733-9. Unique Identifier : AIDSLINE MED/93166225; Kruse H; Kariuki S; Soli N; Olsvik O; Department of Microbiology and Immunology, Norwegian College of; Veterinary Medicine, Oslo.; The antibacterial resistance pattern and minimum inhibitory concentrations (MIC) of 25 Shigella flexneri, 5 S. boydii, 8 S. sonnei, and 3 strains of S. dysenteriae type 2 isolated from Kenyan prostitutes with bacillary dysentery and AIDS were determined, and the applicability of the E-test for MIC determination evalua
Cerebrospinal fluid levels of IL-6 in patients with acute infections of the central nervous system.: Scand J Infect Dis. 1992;24(6):787-91. Unique Identifier : AIDSLINE MED/93166232; Torre D; Zeroli C; Ferraro G; Speranza F; Tambini R; Martegani R; Fiori GP; Division of Infectious Diseases, Regional Hospital, Varese,; Italy.; Interleukin-6 (IL-6) activity was measured in the cerebrospinal fluid (CSF) of patients with acute bacterial or viral meningitis and in AIDS patients with various cerebral disorders. Increased levels of IL-6 were detected in the CSF of patients with bacterial meningitis. On the contrary, most of the samples from patie
OSHA review, student loans among congressional victories.: Tex Med. 1992 Dec;88(12):25. Unique Identifier : AIDSLINE MED/93166399; Ortolon K
Agenda on AIDS.: Tex Med. 1992 Dec;88(12):57. Unique Identifier : AIDSLINE MED/93166411; Albrecht LJ
Oesophageal candidiasis in an HIV-negative individual treated with factor VIII concentrate [letter]: Thromb Haemost. 1992 Dec 7;68(6):782. Unique Identifier : AIDSLINE MED/93166469; Watson HG; Goulden NJ; Ludlam CA
Cryptosporidium: different behaviour in calves of isolates of human origin.: Trans R Soc Trop Med Hyg. 1992 Nov-Dec;86(6):636-8. Unique Identifier : AIDSLINE MED/93166506; Pozio E; Gomez Morales MA; Barbieri FM; La Rosa G; Laboratorio di Parassitologia, Istituto Superiore di Sanita,; Roma, Italy.; The behaviour in calves of 3 Cryptosporidium human isolates was analysed in comparison with a bovine isolate. Twenty-four neonatal calves were infected. An isolate from a patient infected with human immunodeficiency virus (HIV) and showing mild cryptosporidiosis caused severe diarrhoea with a high production of oocyst
Salivary and urinary diagnosis of human immunodeficiency viruses 1 and 2 infection in Cote d'Ivoire, using two assays.: Trans R Soc Trop Med Hyg. 1992 Nov-Dec;86(6):670-1. Unique Identifier : AIDSLINE MED/93166522; Gershy-Damet GM; Koffi K; Abouya L; Sasson-Morokro M; Brattegaard K; Parry JV; De Cock KM; Mortimer PP; Institute Pasteur de Cote d'Ivoire.; This investigation, done at the Institut Pasteur de Cote d Ivoire blind of the previous serological findings, suggests that GACELISA, a commercial immunoglobulin G capture enzyme immunoassay for anti-human immunodeficiency virus antibody, can be successfully applied to unpro
[The coronary sinus as a source of activated T-lymphocytes in patients after orthotopic heart transplantation]: Wien Klin Wochenschr. 1992;104(24):748-52. Unique Identifier : AIDSLINE MED/93166790; Holzinger C; Zuckermann A; Schollhammer A; Kopp C; Imhof M; Laufer G; Griesmacher A; Zwolfer W; Laczkovics A; Wolner E; II. Chirurgische Universitatsklinik, Wien.; Mononuclear cells are the component of blood responsible for allograft recognition, rejection and acceptance. Shifts in the patterns of various mononuclear cell subpopulations were often used as a diagnostic tool in detection of heart rejection. The specificity of mononuclear cell monitoring has remained a controversi
[Differential diagnosis of ascites and abscess forming hepatitis in AIDS patients with reference to the first patient with microsporidia infection in Austria]: Wien Klin Wochenschr. 1992;104(24):753-6. Unique Identifier : AIDSLINE MED/93166791; Armbruster C; Hassl A; Vetter N; II. Interne Abteilung, Pulmologischen Zentrums der Stadt Wien.; We report on a 30 years-old female AIDS patient suffering from generalized pneumocystosis and intestinal microsporidiosis . The chest X-ray showed a right-sided pleural effusion; the lungs showed no areas of consolidation and the heart and the vessels were normal in siz
[Risk of HIV infection in the area of emergency medicine]: Wien Klin Wochenschr Suppl. 1992;194:15-8. Unique Identifier : AIDSLINE MED/93166795; Roggla M; Roggla G; Notfallaufnahme, Allgemeines Krankenhaus, Wien.
[Lymph drainage with secondary lymphedema caused by Kaposi sarcoma]: Z Lymphol. 1992 Dec;16(1):10-3. Unique Identifier : AIDSLINE MED/93166800; Einfeldt H; Abteilung fur Physikalische Therapie, Allgemeinen Krankenhauses; St. Georg, Hamburg.; For reasons not yet known HIV infected patients in the final state of their aids disease often tend to develop Kaposi s sarcoma. These tumours result in secondary lymphatic edema which is found on both sides of the sarcoma up to the regional lymphatic nodes, transferred by the tumour cells. Depending on the state of t
Re: A method for estimating HIV transmission rates among female sex partners of male intravenous drug users [letter; comment]: Am J Epidemiol. 1992 Dec 15;136(12):1532-6. Unique Identifier : AIDSLINE MED/93167222; Blower SM
Access to medical care for HIV-infected individuals under the Americans with Disabilities Act: a duty to treat.: Am J Law Med. 1992;18(3):233-50. Unique Identifier : AIDSLINE MED/93167302; Cohen J; In 1990, Congress enacted the Americans with Disabilities Act (ADA). This Note examines the legislative history of the ADA and uncovers Congress s intent to impose a duty on health care providers to treat people with disabilities unless an individual poses a direct threat to the health or safety of others. This Note p
AIDS: constitutionality of mandatory HIV testing of convicted prostitutes--Illinois v. Adams.: Am J Law Med. 1992;18(3):277-8. Unique Identifier : AIDSLINE MED/93167304
AIDS: court-ordered HIV testing of crime victims--Florida v. Storm.: Am J Law Med. 1992;18(3):278-9. Unique Identifier : AIDSLINE MED/93167305
Blood industry: discovery from anonymous donors--Watson v. Lowcountry Red Cross.: Am J Law Med. 1992;18(3):280-1. Unique Identifier : AIDSLINE MED/93167306
Blood industry: standard of care--United Blood Service v. Quintana.: Am J Law Med. 1992;18(3):281-2. Unique Identifier : AIDSLINE MED/93167307
AIDS nursing: risk or ignorance is no excuse. New HIV/AIDS subspecialty program.: Acad Nurse. 1992 Fall;10(2):18, 20. Unique Identifier : AIDSLINE MED/93168576
The making of an AIDS nurse [interview]: Acad Nurse. 1992 Fall;10(2):19, 21. Unique Identifier : AIDSLINE MED/93168577; Anastasi JK
[The possibility of the vertical intrapartum transmission of the HIV and HB viruses]: Rev Roum Virol. 1992 Jan-Jun;43(1-2):121-3. Unique Identifier : AIDSLINE MED/93168635; Calomfirescu AL; Berca C; Mihaescu V; Steiner N; Popa R; Dinica V; Institut d'hygiene et sante publiques, Bucarest, Roumanie.; A study was performed on 756 serum samples collected from the umbilical cord of newborn infants. HBV markers were found in 4.63% of the tested subjects. Of these samples, 291 were tested for the HIV markers and 0.34% were found positive (versus 0 in the controls, most of them men from the same region). Results confirm
Some seroepidemiological data on HIV-antibody and HBs-antigen prevalence in children and infants of Craiova (Romania).: Rev Roum Virol. 1992 Jan-Jun;43(1-2):59-66. Unique Identifier : AIDSLINE MED/93168644; Voiculescu C; Balasoiu M; Turculeanu A; Filipas L; Popescu E; Sava M; Tieranu E; Cupsa A; Faculty of Medicine, Department of Microbiology, Craiova,; Romania.; By testing 2362 children and infants from Craiova ( Romania ), for both HIV-antibody and HBs-antigen presence in the blood, a high rate of positivity was noticed in orphanages and in dystrophia units. A rate of signal (i.e. about 4% for HIV-antibodies, and 2.5% for HIV-antibody/HBs
HIV-antibody detection in children by competitive and direct micro-ELISA techniques.: Rev Roum Virol. 1992 Jan-Jun;43(1-2):67-72. Unique Identifier : AIDSLINE MED/93168645; Voiculescu C; Turculeanu A; Balasoiu M; Filipas L; Faculty of Medicine, Department of Microbiology, Craiova,; Romania.; A comparative study was carried out on 110 sera from children or infants, suspected of HIV-antibody presence following several micro-ELISA assays, using four direct micro-ELISA (Wellcozyme HIV 1 + 2, Rapid Elavia Mixt, Ortho Diagnostics, RECVIH) and a competitive system--Wellcozyme-Recombinant. In three of the four di
The evolution of hepatitis B virus infection in children with symptomatic AIDS.: Rev Roum Virol. 1992 Jan-Jun;43(1-2):7-11. Unique Identifier : AIDSLINE MED/93168646; Cernescu C; Matusa F; Antipa C; Ruta S; Stefan S. Nicolau Institute of Virology, Bucharest, Romania.; Hepatitis B virus (HBV) markers were determined in 80 children under 5 years of age with HIV symptomatic infection. Because of high carrier rate of hepatitis B virus in Romania we investigated as control a group of age matched 36 HIV negative children offsprings of HBsAg carrier m
Biological roles of HIV Nef proteins. A minireview.: Rev Roum Virol. 1992 Jan-Jun;43(1-2):95-100. Unique Identifier : AIDSLINE MED/93168649; Cernescu C; Ruta S; Stefan S. Nicolau Institute of Virology, Bucharest, Romania.; The nef gene, its protein products and diverse mechanisms by which HIV pathogenicity is nef-mediated in vivo and in vitro explain the huge amount of works on this topic. Until now the following functional roles have been assigned for nef: 1. downregulation of virus replication; 2. GTP binding and GTPase activities; 3.
[Nurses in key positions]: Sairaanhoitaja. 1992;(8):21. Unique Identifier : AIDSLINE MED/93168911; Teras M
[New methods of isolating recombinant proteins]: Cas Lek Cesk. 1992 Dec 4;131(24-25):756-8. Unique Identifier : AIDSLINE MED/93169653; Suttnar J; Dyr JE; Fortova H; Liska V; Vonka V; Ustav hematologie a krevni transfuze, Praha.; Recombinant proteins are isolated from very complex protein mixtures present in the producing cell. The isolation process involves in general four mutually interconnected stages: 1. release of the recombinant protein from the cellular environment, 2. preparation of the specimen for separation, 3. separation, 4. qualit
Perioperative haemotherapy: II. Risks and complications of blood transfusion.: Can J Anaesth. 1992 Oct;39(8):822-37. Unique Identifier : AIDSLINE MED/93169704; Crosby ET; Department of Anaesthesia, Ottawa General Hospital, University of; Ottawa, Ontario, Canada.; Major life-threatening complications following blood transfusion are rare and human error remains an important aetiological factor in many. The infectious risk from blood transfusion is predominantly hepatitis, and non-A, non-B and hepatitis C (HCV) are the most common subtypes noted. The risk of post-transfusion hepa
Soluble factors levels in the initial staging of high-grade non-Hodgkin's lymphomas.: Haematologica. 1992 Nov-Dec;77(6):518-21. Unique Identifier : AIDSLINE MED/93170685; Stasi R; Conforti M; Del Poeta G; Simone MD; Coppetelli U; Tribalto M; Cantonetti M; Perrotti A; Venditti A; Papa G; Divisione di Ematologia, Universita Tor Vergata, Ospedale S.; Eugenio, Roma, Italy.; Plasma levels of several soluble factors were assayed in 31 untreated patients with high-grade non-Hodgkin s lymphomas (NHL). The results showed statistically significant higher average levels of interleukin-2 ( IL-2 ), interleukin-6 (IL-6), interleukin-8 (IL-8), interle
Special considerations for HIV infection in women.: J Am Osteopath Assoc. 1992 Nov;92(11):1437-8. Unique Identifier : AIDSLINE MED/93171106; Tranen BT; This monthly series was developed from the AOA Task Force on AIDS Writers Workshop, held August 16 to 18, 1991, in New York. The workshop was sponsored by an education grant from Burroughs Wellcome. It will provide brief clinical updates and perspectives on the human immunodeficiency virus (HIV). Readers may request
Acid lability is not an intrinsic property of interferon-alpha induced by HIV-infected cells.: J Interferon Res. 1992 Dec;12(6):431-8. Unique Identifier : AIDSLINE MED/93171643; Capobianchi MR; Mattana P; Mercuri F; Conciatori G; Ameglio F; Ankel H; Dianzani F; Institute of Virology, University La Sapienza, Rome, Italy.; Human immunodeficiency virus (HIV)-infected cells induce acid-labile interferon-alpha (al-IFN-alpha) in cultures of mononuclear cells from peripheral human blood. We have investigated the physiochemical properties of such preparations to elucidate the reasons for acid-lability of this IFN. Al-IFN-alpha is a mixture of
Infectious or not? The handpiece controversy.: J N J Dent Assoc. 1992 Summer;63(3):28-9. Unique Identifier : AIDSLINE MED/93172020; Hardie J; Department of Dentistry, Vancouver General Hospital, B.C.,; Canada.
An open letter on the handpiece issue.: J N J Dent Assoc. 1992 Summer;63(3):31-3. Unique Identifier : AIDSLINE MED/93172021; Neiburger EJ
OSHA--an agency run amok.: J N J Dent Assoc. 1992 Summer;63(3):63-6. Unique Identifier : AIDSLINE MED/93172022; Carter SD
[Three cases of chronic respiratory tract lesions associated with adult T-cell leukemia (ATL)]: Nippon Kyobu Shikkan Gakkai Zasshi. 1992 Dec;30(12):2134-8. Unique Identifier : AIDSLINE MED/93172623; Taguchi H; Takaoka K; Nasuhara Y; Kawakami Y; Department of Respiratory Medicine, Nikko Memorial Hospital,; Muroan, Japan.; Three cases of chronic respiratory tract lesions as a complication of adult T-cell leukemia (ATL) are reported. Case 1 was seropositive for HTLV-1 on recent examination following treatment of bronchiolitis. Chest radiograph revealed over inflation of the lungs and bilateral diffuse small nodular shadows. Pulmonary fun
Using the PRECEDE model to determine junior high school students' knowledge, attitudes, and beliefs about AIDS.: J Sch Health. 1992 Dec;62(10):464-70. Unique Identifier : AIDSLINE MED/93172720; Alteneder RR; Price JH; Telljohann SK; Didion J; Locher A; School of Nursing, Medical College of Ohio, Toledo 43699.; The effectiveness of a one-period school-based AIDS education program on an adolescent population of seventh and eighth grade students (N = 585) was determined. An instrument based on the PRECEDE model was used to assess program effectiveness. Three-way analysis of variance indicated significant differences (p v .01)
HIV instruction and selected HIV-risk behaviors among high school students--United States, 1988-1991.: J Sch Health. 1992 Dec;62(10):481-2. Unique Identifier : AIDSLINE MED/93172724
Routine HIV testing before surgery.: Nurs RSA. 1992 Nov-Dec;7(11-12):51. Unique Identifier : AIDSLINE MED/93173172; Maartens G; Knottenbelt J
Zidovudine effective in all ethnic groups [news]: Nurs RSA. 1992 Nov-Dec;7(11-12):53. Unique Identifier : AIDSLINE MED/93173173
Clinical update: AIDS [news]: Nurs RSA. 1992 Aug;7(8):11. Unique Identifier : AIDSLINE MED/93173174
Imaging of human T-lymphotropic virus type I-associated chronic progressive myeloneuropathies.: Neuroradiology. 1992;35(1):69-74. Unique Identifier : AIDSLINE MED/93173288; Alcindor F; Valderrama R; Canavaggio M; Lee H; Katz A; Montesinos C; Madrid RE; Merino RR; Pipia PA; Department of Neurology, State University of New York, Brooklyn.; We studied magnetic resonance imaging (MRI) of the head and cervical spine and CT of the head in 46 patients (14 men, 32 women) with chronic progressive myeloneuropathy. The findings were correlated with human T-lymphotropic virus type I (HTLV-I) serology, race, country of origin, and age. We found a female predominan
Activities of HIV-RNA targeted ribozymes transcribed from a 'shot-gun' type ribozyme-trimming plasmid.: Nucleic Acids Symp Ser. 1992;(27):15-6. Unique Identifier : AIDSLINE MED/93173622; Ohkawa J; Yuyama N; Taira K; Fermentation Research Institute, Agency of Industrial Science &; Technology, MITI, Tsukuba Science City, Japan.; We have constructed a shot-gun type ribozyme-trimming system. By concatenating several units, each consisting of a trans-acting ribozyme (targeted to HIV-RNA) and cis-acting ribozymes (trimming 5 - and 3 -ends of the trans-acting ribozyme), several kinds of trans-acting ribozymes can be liberated upon transcription an
HIV tests need time and funds [news]: Nurs Times. 1992 Dec 30-1993 Jan 5;88(52):5. Unique Identifier : AIDSLINE MED/93173708
The use of hypnosis with hemophilia.: Psychiatr Med. 1992;10(4):89-98. Unique Identifier : AIDSLINE MED/93174021; LaBaw W; University of Colorado Health Sciences Center, Denver.; The Colorado program to treat hemophiliacs using hypnosis has been described. Those using hypnosis have realized a reduction in the need for transfusions, which results in a decrease in the development of inhibitors, less potential exposure to the AIDS virus and a lower incidence of liver and kidney damage. A decrease
[AIDS: to be better defined... (news)]: Rev Infirm. 1992 Sep;42(14):4. Unique Identifier : AIDSLINE MED/93174129
[Nursing care for asylum seekers]: Soins. 1992 Aug-Sep;(563-564):18-9. Unique Identifier : AIDSLINE MED/93174311; Henin F
[Tuberculosis: answers and perspectives]: Soins. 1992 Aug-Sep;(563-564):56-61. Unique Identifier : AIDSLINE MED/93174322; Krespine C
[Early dementia]: Soins Psychiatr. 1992 Oct;(144):47-8. Unique Identifier : AIDSLINE MED/93174354; Ghodhbane T
[The immunoenzyme detection of the HIV-1 antigen by using monoclonal antibodies to protein p24]: Vopr Virusol. 1992 Sep-Dec;37(5-6):229-32. Unique Identifier : AIDSLINE MED/93174983; Shumai EP; Vorob'ev SM; Makarova NE; Tugizov ShM; Zverev VV; Kushch AA; A test system using monoclonal antibodies to HIV p24 was developed for solid-phase ELISA for detection of HIV antigen (AG) which helped detect the content of AG in samples with trace concentrations, less than 25 pg/ml. The test system can be used for AG monitoring in natural specimens (serum of HIV-infected patients a
[The anti-HIV activity of beta-glycyrrhizic acid]: Vopr Virusol. 1992 Sep-Dec;37(5-6):235-8. Unique Identifier : AIDSLINE MED/93174985; Pliasunova OA; Egoricheva IN; Fediuk NV; Pokrovskii AG; Baltina LA; Murinov IuI; Tolstikov GA; The anti-HIV activity of beta-glycyrrhizic acid (GA) and various derivatives was studied using various strains of HIV-1 and HIV-2 in primary infected lymphoblastoid cells MT-4 and monocyte cell line U-973 chronically infected with HIV-1 and containing provirus (GKV 4005). Beta-glycyrrhizic acid and its derivatives wer
AIDS in CAREC member countries--a statistical update.: West Indian Med J. 1992 Dec;41(4):172-4. Unique Identifier : AIDSLINE MED/93175010; Gayle C; Caribbean Epidemiology Centre Trinidad, W.I.
The pre-travel medical evaluation: the traveler with chronic illness and the geriatric traveler.: Yale J Biol Med. 1992 Jul-Aug;65(4):317-27. Unique Identifier : AIDSLINE MED/93175049; Patterson JE; Yale University School of Medicine, New Haven, Connecticut.; The pre-travel medical evaluation of elderly patients and patients with chronic illness requires special assessment and advice. Screening and special precautions are reviewed for traveling patients with respiratory disease, cardiac disease, sinusitis, diabetes mellitus, HIV infection, and other chronic medical conditi
[Evaluation of immunological studies in patients with rheumatoid arthritis]: Ann Acad Med Stetin. 1992;38:141-55. Unique Identifier : AIDSLINE MED/93175711; Ostanek L; Kliniki Hematologii Instytutu Chorob Wewnetrznych Pomorskiej; Akademii Medycznej.; Immunological studies are widely applicable at a clinic in rheumatoid patients, despite the fact that their clinical value is still a disputable subject. Many authors are of opinion that the determination of individual immunological tests does not provide the estimation of immunological state in patients, and should b
Cellular localization of Nef expressed in persistently HIV-1-infected low-producer astrocytes [published erratum appears in AIDS 1993 Mar;7(3):following 444]: AIDS. 1992 Dec;6(12):1427-36. Unique Identifier : AIDSLINE MED/93152025; Kohleisen B; Neumann M; Herrmann R; Brack-Werner R; Krohn KJ; Ovod V; Ranki A; Erfle V; Institut fur Molekulare Virologie, GSF Forschungszentrum fur; Umwelt und Gesundheit, Neuherberg, Germany.; OBJECTIVES: The characterization and localization of HIV-1 Nef highly expressed in permanently infected astrocytes (TH4-7-5) as a model for latent infection of human brain cells. DESIGN: Immunochemical methods are an appropriate tool to investigate expression and localization of cellular proteins. METHODS: Nef express
HIV disease and pregnancy [letter; comment]: J Obstet Gynecol Neonatal Nurs. 1992 Nov-Dec;21(6):445. Unique Identifier : AIDSLINE MED/93155780; Wilson PJ
Expression of B-type Epstein-Barr virus in HIV-infected patients and cardiac transplant recipients.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1869-74. Unique Identifier : AIDSLINE MED/93143996; Kyaw MT; Hurren L; Evans L; Moss DJ; Cooper DA; Benson E; Esmore D; Sculley TB; Queensland Institute of Medical Research, Herston, Brisbane,; Australia.; In the present study, peripheral blood mononuclear cells (PBMCs) were obtained from HIV+ subjects as well as cardiac transplant recipients, and the presence of A- and B-type Epstein-Barr virus (EBV) was determined using the polymerase chain reaction (PCR). Of the HIV+ patients studied, 24% were found to be infected wi
New drug prophylaxis for M avium infection [news]: Nurs Stand. 1992 Dec 9-15;7(12):17. Unique Identifier : AIDSLINE MED/93144140
[Annual cost of microbial immunological tests for HIV-positive individuals in a hospital center]: Enferm Infecc Microbiol Clin. 1992 Oct;10(8):462-5. Unique Identifier : AIDSLINE MED/93144374; Maroto MC; Piedrola D; Quiros E; Garcia F; Bernal MC; Servicio de Microbiologia, Hospital Universitario, Granada.; The goal of this study is to increase the knowledge of the AIDS cost in a hospital. We have studied the HIV patients diagnosed during a year in our hospital and the charges of the serological tests performed to them. 20.8% of the tests were to study antibodies against HIV (only 20% were positive). After patient distri
Recombinant human growth hormone promotes human lymphocyte engraftment in immunodeficient mice and results in an increased incidence of human Epstein Barr virus-induced B-cell lymphoma.: Brain Behav Immun. 1992 Dec;6(4):355-64. Unique Identifier : AIDSLINE MED/93144826; Murphy WJ; Durum SK; Anver M; Frazier M; Longo DL; National Cancer Institute-Frederick Cancer Research and; Development Center, Maryland 21702-1201.; Recombinant human growth hormone (rhGH) previously has been demonstrated to promote human or mouse T-cell engraftment in immunodeficient mice. We then wanted to examine long-term effects of rhGH on human cell engraftment in these mice. Mice with severe combined immune deficiency (SCID) were given human peripheral bloo
AIDS associated non-Hodgkin's lymphomas represent a broad spectrum of monoclonal and polyclonal lymphoproliferative processes.: Curr Top Microbiol Immunol. 1992;182:385-94. Unique Identifier : AIDSLINE MED/93145709; Herndier BG; Shiramizu BT; McGrath MS; Department of Pathology, University of California, San Francisco; General Hospital 94110.
[Oxidative stress in 29 HIV seropositive patients. Two-year results of a double-blind trial of diethyldithiocarbamate versus placebo]: Presse Med. 1992 Nov 14;21(38):1809-12. Unique Identifier : AIDSLINE MED/93149983; Coutellier A; Bonnefont-Rousselot D; Delattre J; Lopez O; Jaudon MC; Herson S; Emerit J; Service de Medecine interne, Hopital de La Salpetriere,; Paris.; Among 29 seropositive subjects who had participated in the HIV 87 therapeutic trial (Merieux laboratories), the oxidative stress was evaluated at 24 months in 16 treated with diethyldithiocarbamate (dithiocarb) and in 13 who had received the placebo. No significant difference was found between these two groups, wherea
Serological evidence for the presence of bovine lentivirus infection in cattle in Australia [letter]: Aust Vet J. 1992 Dec;69(12):337. Unique Identifier : AIDSLINE MED/93151800; Forman AJ; Gibson CA; Rodwell BJ
Pathogenesis and therapy of HIV-1 infection of the central nervous system [editorial]: AIDS. 1992 Dec;6(12):1411-26. Unique Identifier : AIDSLINE MED/93152024; Geleziunas R; Schipper HM; Wainberg MA
Identification and evaluation of new primer sets for the detection of lentivirus proviral DNA.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):1981-9. Unique Identifier : AIDSLINE MED/93152271; Gelman IH; Zhang J; Hailman E; Hanafusa H; Morse SS; Department of Microbiology, Mount Sinai Medical Center, New York,; NY 10029.; We have developed sets of degenerate oligonucleotides designed to detect pol gene sequences from any member of the lentivirus subfamily when used as primers in amplification techniques such as the polymerase chain reaction (PCR). This pan-lentivirus-specific primer set (PLSPS) consists of primers, LV1, LV2, and LV3, b
Infection by human herpesvirus 6 (HHV-6) of human lymphoid T cells occurs through an endocytic pathway.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):2031-7. Unique Identifier : AIDSLINE MED/93152276; Cirone M; Zompetta C; Angeloni A; Ablashi DV; Salahuddin SZ; Pavan A; Torrisi MR; Frati L; Faggioni A; Dipartimento di Medicina Sperimentale, Universita degli Studi La; Sapienza, Rome, Italy.; We have analyzed by immunoelectron microscopy the early events of binding and internalization of human herpesvirus 6 (HHV-6, strain GS) on a susceptible T-lymphoblastoid cell line, HSB-2. The virions bound to the cell surface at 4 degrees C were tightly associated with the plasma membrane. Gold immunolabeling of the v
'It wasn't hepatitis and it wasn't pneumonia': tuberculosis returns.: Tenn Nurse. 1992 Dec;55(6):4. Unique Identifier : AIDSLINE MED/93152582; Edwards F
Coexistence of acute monoblastic leukemia and adult T-cell leukemia: possible association with HTLV-I infection in both cases?: Leuk Lymphoma. 1992 Sep;8(1-2):147-55. Unique Identifier : AIDSLINE MED/93153370; Tokioka T; Shimamoto Y; Funai N; Nagumo F; Motoyoshi K; Tadano J; Yamaguchi M; Department of Internal Medicine, Saga Medical School, Japan.; A 64 year-old Japanese man who developed acute monoblastic leukemia during the course of adult T-cell leukemia/lymphoma (ATL) was studied. Leukemic cells in the peripheral blood and bone marrow were monoblasts positive for alpha-naphthol butyrate esterase (alpha-NBE) staining, CD11c and CD36 antigens, whereas tumor ce
[Study by in situ hybridization of the prevalence of herpes virus as cofactors of the tumoral development of papillomatous lesions of the anogenital region in seropositive and seronegative men against HIV]: C R Seances Soc Biol Fil. 1992;186(3):231-41. Unique Identifier : AIDSLINE MED/93153676; Bernard C; Mougin C; Rossel M; Laurent R; Lab M; Laboratoire de Virologie, CHU St-Jacques, Besancon.; Infection with specific types of HPV has emerged as necessary but not sufficient factor in the neoplastic transformation of anogenital condylomas. Some viruses (HIV, Herpes viridae: HSV, CMV , EBV) might act as cofactors in the neoplastic changes and cancer. To s
In vitro and in vivo toxicity of 2',3'-dideoxycytidine in mice.: Chem Biol Interact. 1992 Dec;85(2-3):255-63. Unique Identifier : AIDSLINE MED/93153846; Rossi L; Brandi G; Schiavano GF; Chiarantini L; Albano A; Magnani M; Istituto di Chimica Biologica G. Fornaini, Universita degli; Studi 61029, Urbino, Italy.; 3T3 mouse embryo fibroblast cell growth was inhibited in a concentration dependent manner by 2 ,3 -dideoxycytidine (ddCyd), a strong inhibitor of human immunodeficiency virus. Cell growth inhibition was associated with an increased incorporation of ddCyd into cell DNA. In contrast SP2/0-Ag14 (a mouse myeloma) cell gro
Structural analysis of 2',3'-dideoxyinosine, 2',3'-dideoxyadenosine, 2',3'-dideoxyguanosine and 2',3'-dideoxycytidine by 500-MHz 1H-NMR spectroscopy and ab-initio molecular orbital calculations.: J Biochem Biophys Methods. 1992 Dec;25(4):253-72. Unique Identifier : AIDSLINE MED/93155439; Plavec J; Koole LH; Chattopadhyaya J; Department of Bioorganic Chemistry, University of Uppasala,; Sweden.; Solution structure of anti-AIDS drug, 2 ,3 -dideoxyinosine (ddI) has been assessed by NMR spectroscopy and pseudorotational analysis in conjunction with its analogues: 2 ,3 -dideoxyadenosine (ddA), 2 ,3 -dideoxyguanosine (ddG) and 2 ,3 -dideoxycytidine ( d
Genital human papillomavirus infection in women.: J Obstet Gynecol Neonatal Nurs. 1992 Nov-Dec;21(6):503-15. Unique Identifier : AIDSLINE MED/93155787; Kelley KF; Galbraith MA; Vermund SH; AIDS Epidemiology Program, New York State Department of Health,; Albany.; OBJECTIVE: To enhance nurse clinicians knowledge of genital human papillomavirus infection in women. DATA SOURCES: Several literature searches using the following terms, dating back to 1986: human papillomavirus (HPV), females, human, cervical neoplasia, risk factors, condylomata acuminata, detection, epidemiology, p
Opportunistic intraocular infections in AIDS.: Trans Am Ophthalmol Soc. 1992;90:97-108; discussion 108-9. Unique Identifier : AIDSLINE MED/93158125; Morinelli EN; Dugel PU; Lee M; Klatt EC; Rao NA; Pathology Laboratory, Doheny Eye Institute, University of; Southern California School of Medicine, Los Angeles.; In conclusion, this clinicopathologic study has shown that CMV ocular infection is present in about 16% of terminal AIDS patients. The treatment of CMV retinitis reduces the number of CMV-infected nonocular organs and may also lessen the severity and control the
A recombinant-based feline immunodeficiency virus antibody enzyme-linked immunosorbent assay.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):133-41. Unique Identifier : AIDSLINE MED/93158174; Mermer B; Hillman P; Harris R; Krogmann T; Tonelli Q; Palin W; Andersen P; IDEXX Laboratories, Westbrook, ME 04092.; We have developed an antibody detection enzyme-linked immunosorbent assay (ELISA) for the identification of animals infected by feline immunodeficiency virus (FIV). The ELISA solid-phase antigen consists of recombinant FIV gag proteins expressed in bacteria. The proteins are purified from bacterial lysates as insolubl
A recombinant feline immunodeficiency virus envelope fusion protein stimulates peripheral blood lymphocytes from naive cats to proliferate in vitro.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):143-53. Unique Identifier : AIDSLINE MED/93158175; Beatty JA; Reid G; Rigby MA; Neil JC; Jarrett O; Browning MJ; Department of Veterinary Pathology, University of Glasgow; Veterinary School, UK.; A region of feline immunodeficiency virus (FIV)/Glasgow-8 external envelope glycoprotein (env) incorporating the third and fourth variable regions (V3/V4) was cloned, inserted into the pGEX vector and expressed in Escherichia coli to yield milligram quantities of the recombinant polypeptide as a fusion protein with gl
Long-term clinical observations on feline immunodeficiency virus infected asymptomatic carriers.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):15-22. Unique Identifier : AIDSLINE MED/93158176; Ishida T; Taniguchi A; Matsumura S; Washizu T; Tomoda I; Department of Clinical Pathology, Nippon Veterinary and Animal; Science University, Tokyo, Japan.; Eleven feline immunodeficiency virus (FIV) infected asymptomatic carrier (AC) cats were observed for 2 years for development of acquired immunodeficiency syndrome (AIDS). Four of the 11 (36.4%) showed progression of the clinical stage. Persistent generalized lymphadenopathy was noted in three cats as the first sign of
Evaluation of 9-(2-phosphonylmethoxyethyl) adenine therapy for feline immunodeficiency virus using a quantitative polymerase chain reaction.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):155-66. Unique Identifier : AIDSLINE MED/93158177; Philpott MS; Ebner JP; Hoover EA; Department of Pathology, Colorado State University, Fort Collins; 80523.; To determine the efficacy of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) as a prophylactic chemotherapeutic agent for the treatment of lentivirus infections, three groups of specific pathogen free cats were treated with 0, 3, or 6 mg kg-1 twice daily doses of PMEA beginning 24 h prior to virus challenge with feline imm
Pilot study of the effect of acemannan in cats infected with feline immunodeficiency virus.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):177-89. Unique Identifier : AIDSLINE MED/93158179; Yates KM; Rosenberg LJ; Harris CK; Bronstad DC; King GK; Biehle GA; Walker B; Ford CR; Hall JE; Tizard IR; Carrington Laboratories, Irving, TX 75062.; Acemannan, a complex carbohydrate shown to stimulate interleukin-1, tumor necrosis factor alpha and prostaglandin E2 production by macrophages, has also demonstrated antiviral activity in vitro against human immunodeficiency virus, Newcastle disease virus and influenza virus. A pilot study was undertaken to determine
Enhancement after feline immunodeficiency virus vaccination.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):191-7. Unique Identifier : AIDSLINE MED/93158180; Hosie MJ; Osborne R; Reid G; Neil JC; Jarrett O; University of Glasgow, Department of Veterinary Pathology, UK.; Cats were vaccinated with one of the three preparations: purified feline immunodeficiency virus (FIV) incorporated into immune stimulating complexes (ISCOMs), recombinant FIV p24 ISCOMs, or a fixed, inactivated cell vaccine in quil A. Cats inoculated with the FIV ISCOMs or the recombinant p24 ISCOMs developed high tit
Retrovirus infections in non-domestic felids: serological studies and attempts to isolate a lentivirus.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):215-24. Unique Identifier : AIDSLINE MED/93158182; Lutz H; Isenbugel E; Lehmann R; Sabapara RH; Wolfensberger C; Department of Veterinary Medicine, University of Zurich,; Switzerland.; An African lioness from the Zoo of Zurich had to be euthanized because of an inoperable tumor. The serum tested negative for feline leukemia virus (FeLV) p27 antigen by enzyme-linked immunosorbent assay (ELISA) but was strongly positive for feline immunodeficiency virus (FIV) antibodies by ELISA and Western blot. When
Feline immunodeficiency virus neurotropism: evidence that astrocytes and microglia are the primary target cells.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):23-35. Unique Identifier : AIDSLINE MED/93158183; Dow SW; Dreitz MJ; Hoover EA; Department of Pathology, College of Veterinary Medicine and; Biomedical Sciences, Colorado State University, Fort Collins; 80503.; To investigate the neuropathogenesis of feline immunodeficiency virus (FIV) infection in vitro, we have utilized three populations of cultured feline neural cells (astrocytes, microglia, brain endothelium) to assess the relative susceptibility to FIV infection, ability to produce viral antigens, and effects of infecti
Clinical and pathological findings in feline immunodeficiency virus experimental infection.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):3-13. Unique Identifier : AIDSLINE MED/93158184; Callanan JJ; Thompson H; Toth SR; O'Neil B; Lawrence CE; Willett B; Jarrett O; Department of Veterinary Pathology, University of Glasgow, UK.; A study is described of the clinical and pathological findings in 20 specific pathogen free cats infected when 1 year old with feline immunodeficiency virus and monitored over 12 months. Cats were divided into two groups (A and B). The clinical and clinicopathological features were studied in Group A. In Group B, at 1
Detection of feline immunodeficiency virus infection in bone marrow of cats.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):37-49. Unique Identifier : AIDSLINE MED/93158185; Beebe AM; Gluckstern TG; George J; Pedersen NC; Dandekar S; Department of Internal Medicine, School of Medicine, University; of California, Davis 95616.; Natural or experimental feline immunodeficiency virus (FIV) infection in cats is often associated with hematologic abnormalities which are similar to those observed in human immunodeficiency virus (HIV) infected patients. To determine if cells in bone marrow are infected with FIV and whether severity of hematopoietic
Decreased mitogen responsiveness and elevated tumor necrosis factor production in cats shortly after feline immunodeficiency virus infection.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):51-9. Unique Identifier : AIDSLINE MED/93158186; Lawrence CE; Callanan JJ; Jarrett O; Department of Veterinary Pathology, University of Glasgow, UK.; We present the results of an investigation into the effects of feline immunodeficiency virus (FIV) infection on the response to mitogens and cytokine production in the first month of infection. We were able to demonstrate a depression of response of peripheral blood mononuclear cells to the mitogens concanavalin A, ph
Tumor necrosis factor alpha levels in cats experimentally infected with feline immunodeficiency virus: effects of immunization and feline leukemia virus infection.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):61-9. Unique Identifier : AIDSLINE MED/93158187; Lehmann R; Joller H; Haagmans BL; Lutz H; Department of Veterinary Medicine, University of Zurich,; Switzerland.; Tumor necrosis factor alpha (TNF alpha) levels were determined by enzyme-linked immunosorbent assay (ELISA) and by cell culture bioassay in supernatants of lipopolysaccharide-stimulated feline monocyte cultures and in cat serum samples. There was a good correlation between the results obtained by the two methods. From
Transmission of feline immunodeficiency virus from infected queens to kittens.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):83-93. Unique Identifier : AIDSLINE MED/93158189; Wasmoen T; Armiger-Luhman S; Egan C; Hall V; Chu HJ; Chavez L; Acree W; Department of Biological Research and Development, Fort Dodge; Laboratories, IA 50501.; This study demonstrates the transmission of feline immunodeficiency virus (FIV) from infected queens to kittens in two separate litters. Queen 1 was infected by intravenous administration of FIV at 22 days prior to parturition. Two out of three kittens from the litter were found to be viremic at 10 weeks of age as det
[The legal and ethical aspects of nerve tissue transplantation]: Zh Vopr Neirokhir Im N N Burdenko. 1992 Nov-Dec;(6):12-3. Unique Identifier : AIDSLINE MED/93158305; Sramka M; Rattaj M; The authors have specified the following criteria for the withdrawal of embryonal tissue at their department: 1) only tissue from dead fetus is allowed to be used in neurotransplantation; 2) embryonal tissue is to be obtained after spontaneous abortions from volunteers or from women asking for artificial abortion; 3)
The absence of genital human papillomavirus DNA in virginal women.: Int J STD AIDS. 1992 Nov-Dec;3(6):414-7. Unique Identifier : AIDSLINE MED/93160302; Fairley CK; Chen S; Tabrizi SN; Leeton K; Quinn MA; Garland SM; Department of Microbiology, Royal Women's Hospital, Carlton,; Victoria, Australia.; Our aim was to determine the prevalence of human papillomavirus (HPV) infection in virginal women and to establish if other forms of sexual activity not involving penetration may contribute to the transmission of this infection. Female patients attending medical practitioners, and female high school students were recr
Azithromycin (Sumamed-Pliva) in the treatment of chlamydial genital tract infections in infertile marriages [letter]: Int J STD AIDS. 1992 Nov-Dec;3(6):448-9. Unique Identifier : AIDSLINE MED/93160313; Lazarova Z; Kazar J; Auxtova S; Rollova I; Krupova M; Pec M; Pec J
CDC advises on management of persons exposed to multiple-drug-resistant tuberculosis [news]: Clin Pharm. 1992 Dec;11(12):991, 994, 999. Unique Identifier : AIDSLINE MED/93161678
Prevalence of herpesvirus, human T-lymphotropic virus type 1, and treponemal infections in Southeast Asian refugees.: J Med Virol. 1992 Nov;38(3):195-9. Unique Identifier : AIDSLINE MED/93163775; Buchwald D; Hooton TM; Ashley RL; Department of Medicine, University of Washington, Seattle.; Sera obtained for treponemal serology (VDRL) from 193 Southeast Asian refugees representing five ethnic groups seen in a primary care clinic were examined for antibodies to human T-lymphotropic virus type 1 (HTLV-1), human herpes-virus-6 (HHV-6), Epstein-Barr virus (EBV), and cytomegal
[Chronic fatigue syndrome and virus infection: human herpesvirus 6 (HHV-6) infection]: Nippon Rinsho. 1992 Nov;50(11):2612-6. Unique Identifier : AIDSLINE MED/93164422; Yamanishi K; Research Institute for Microbial Diseases, Osaka University.; Chronic fatigue syndrome (CFS) is newly-recognized disease characterized by chronic and debilitating fatigue. It has been suggested that viral infection may be involved in this syndrome from the results of clinical examination, including increased activity of 2 ,5 -synthetase in leukocytes of patients. The following v
[Symptoms, signs and laboratory findings in patients with chronic fatigue syndrome]: Nippon Rinsho. 1992 Nov;50(11):2665-72. Unique Identifier : AIDSLINE MED/93164430; Kuratsune H; Yamaguti K; Hattori H; Tazawa H; Takahashi M; Yamanishi K; Kitani T; Department of Clinical Research, Osaka University.; This review summarizes the symptoms, signs and laboratory abnormalities seen in 59 patients with chronic fatigue syndrome (CFS), 2 patients with post-infectious CFS and in 26 patients with possible CFS whose illnesses fulfill the criteria proposed by the study group of the Ministry of Welfare,
Health care workers and HIV.: Kans Med. 1992 Dec;93(12):318. Unique Identifier : AIDSLINE MED/93164535; Stratton WT
Augmentation of bovine leukemia virus (BLV)-specific lymphocyte proliferation responses in ruminants by inoculation with BLV env-recombinant vaccinia virus: their role in the suppression of BLV replication.: Microbiol Immunol. 1992;36(12):1317-23. Unique Identifier : AIDSLINE MED/93164901; Ohishi K; Suzuki H; Yasutomi Y; Onuma M; Okada K; Numakunai S; Ohshima K; Ikawa Y; Sugimoto M; Corporate Research and Development Laboratory, Tonen Corporation,; Saitama, Japan.; Lymphocyte proliferation responses were investigated in sheep and cattle, in which the replication of bovine leukemia virus (BLV) had been known to be suppressed by inoculation with recombinant vaccinia virus (rVV) expressing BLV envelope glycoprotein (gp60). Enhanced lymphocyte proliferation responses were observed i
CDC occupational HIV surveillance system [news]: Infect Control Hosp Epidemiol. 1992 Dec;13(12):758. Unique Identifier : AIDSLINE MED/93171568
CT and MRI: prognostic tools in patients with AIDS and neurological deficits.: Neuroradiology. 1992;35(1):75-8. Unique Identifier : AIDSLINE MED/93173289; Mundinger A; Adam T; Ott D; Dinkel E; Beck A; Peter HH; Volk B; Schumacher M; Department of Diagnostic Radiology, University of Freiburg,; Federal Republic of Germany.; To determine the prognostic value of CT and MRI in AIDS we studied the survival of patients with neurological involvement, in relation to the initial imaging results. Twenty-six initial CT and 15 MRI examinations of 41 patients were reviewed for the presence of cerebral atrophy and/or focal lesions. The mean survival
[Variants of the interaction of the human T-cell leukemia virus (HTLV-I) with the B-cells of lymphoblastoid lines]: Vopr Virusol. 1992 Sep-Dec;37(5-6):232-5. Unique Identifier : AIDSLINE MED/93174984; Iakovleva LS; Pavlish OA; Tupitsin NN; Gurtsevich VE; B-cell lymphoblastoid lines which are known to be derived by in vitro inoculation of B-lymphocytes with Epstein-Barr herpes virus (EBV) were shown to be infected with HTLV-1. Three possible variants of HTLV-1 interaction with cells were demonstrated by immunoblot, polymerase chain reaction, and virus isolation: (1) pr
Immunizations for foreign travel.: Yale J Biol Med. 1992 Jul-Aug;65(4):293-315. Unique Identifier : AIDSLINE MED/93175048; Hill DR; The International Traveler's Medical Service, University of; Connecticut Health Center, Farmington 06030-3212.; One of the most important aspects of preparing travelers for destinations throughout the world is providing them with immunizations. Before administering any vaccines, however, a careful health and immunization history and travel itinerary should be obtained in order to determine vaccine indications and contraindicati
HTLV: non-HIV retroviruses of man.: Acta Clin Belg. 1992;47(6):371-6. Unique Identifier : AIDSLINE MED/93175152; Goubau P; Rega Instituut, Leuven.
The pathogenesis of AIDS lymphomas: a foundation for addressing the challenges of therapy and prevention.: Leuk Lymphoma. 1992 Oct;8(3):167-88. Unique Identifier : AIDSLINE MED/93145018; Karp JE; Broder S; Office of the Director, National Cancer Institute, Bethesda,; Maryland 20892.; The association between AIDS and a spectrum of malignancies relates to chronic, profound defects in both cellular and humoral mechanisms of immune surveillance. Ironically, as AIDS patients live longer in response to increasingly effective antiretroviral therapies, the incidence of AIDS-related malignancies will conti
Changes on distribution of CD4+/CD45RA- and CD8+/CD11- cells in tumor-infiltrating lymphocytes of renal cell carcinoma associated with tumor progression.: Eur Urol. 1992;22(4):323-8. Unique Identifier : AIDSLINE MED/93146062; Igarashi T; Murakami S; Takahashi H; Matsuzaki O; Shimazaki J; Department of Urology, Asahi General Hospital, Chiba, Japan.; To study the distribution of subsets of T cells in renal cell carcinoma, peripheral blood lymphocytes (PBL) and tumor-infiltrating lymphocytes (TIL) were analyzed in 43 untreated patients using two-color flow cytometry. An increase in the relative number of CD4+/CD45RA-, CD8+/CD11- and HLA-DR+/CD3+ cells was shown in
Failure to control AIDS-related CMV-retinitis with intravenous ganciclovir.: Int Ophthalmol. 1992 Nov;16(6):453-7. Unique Identifier : AIDSLINE MED/93146784; Bernauer W; Meyer P; Zimmerli W; Daicker B; Ruettimann S; University Eye Hospital, Basel, Switzerland.; Between January 1988 and May 1991 intravenous ganciclovir (GCV) treatment was administered to eight male AIDS-patients with unilateral cytomegalovirus ( CMV )-retinitis. Despite of continuous therapy with at least the recommend
Negative seroactivity to HTLV-1 in Sephardic Jews and Arabs with Behcet's disease [letter; comment]: J Rheumatol. 1992 Nov;19(11):1822-3. Unique Identifier : AIDSLINE MED/93148275; Yosipovitch G; Weinberger A; Shochat B
Zidovudine therapy in combination with intravenous immunoglobulin in HIV infected children.: Scott Med J. 1992 Oct;37(5):138-41. Unique Identifier : AIDSLINE MED/93150282; Croft N; Yap PL; Mok JY; Hague RA; Burns SM; Regional Infectious Diseases Unit, City Hospital, Edinburgh.; There is little published data on concomitant use of zidovudine and intravenous immunoglobulin (IV IgG). In this paper we review our experience of four HIV-1 infected children treated with zidovudine for periods of 19-33 months (mean 26.5 months) subsequent to starting IV IgG for period of 18-20 months (mean 19 months
Granulocyte-macrophage colony-stimulating factor: present status.: Semin Hematol. 1992 Oct;29(4 Suppl 3):1-3. Unique Identifier : AIDSLINE MED/93150317; Shadduck RK; Pennsylvania Cancer Institute, West Penn Hospital, Pittsburgh, PA; 15224.
Intractable chronic furunculosis: prevention of recurrences with pentoxifylline.: Acta Derm Venereol. 1992 Nov;72(6):461-2. Unique Identifier : AIDSLINE MED/93150798; Wahba-Yahav AV; A 60-year-old HIV-negative man with known noninsulin-dependent diabetes mellitus and glucose 6-phosphate-dehydrogenase deficiency anemia suffered from chronic recurrent furunculosis since the age of 30. In recent years, his condition had become increasingly severe and the recurrences increasingly frequent. Different m
A sero-epidemiological study on mother-to-child transmission of HTLV-I in southern Kyushu, Japan.: Asia Oceania J Obstet Gynaecol. 1992 Dec;18(4):371-7. Unique Identifier : AIDSLINE MED/93151777; Oki T; Yoshinaga M; Otsuka H; Miyata K; Sonoda S; Nagata Y; Department of Obstetrics and Gynecology, Faculty of Medicine,; Kagoshima University, Japan.; In vertical transmission of HTLV-I the duration of breast-feeding seems to be an important risk factor. In this study, we made prospective and retrospective surveys on the rate of vertical transmission of HTLV-I in infants and their siblings born to HTLV-I seropositive mothers. The results obtained were as follows. (1
PASSHIV-1 treatment of patients with HIV-1 infection. A preliminary report of a phase I trial of hyperimmune porcine immunoglobulin to HIV-1.: AIDS. 1992 Dec;6(12):1457-64. Unique Identifier : AIDSLINE MED/93152029; Osther K; Wiik A; Black F; Skinhoj P; Kellermann G; Ugen KE; Williams WV; Weiner DB; Verigen Inc., Hopkinton, MA 01748.; OBJECTIVE: To study the safety of intravenously administered porcine-derived hyperimmune immunoglobulin to HIV-1, PASSHIV-1, in humans. METHODS: Fourteen HIV-1-infected individuals were treated for 5-7 days with intravenous infusions of highly purified PASSHIV-1 (> 95% pure). Two of the 14 patients were retreated 3 mo
Salmonella, Campylobacter and Shigella in HIV-seropositive patients [see comments]: AIDS. 1992 Dec;6(12):1495-8. Unique Identifier : AIDSLINE MED/93152035; Nelson MR; Shanson DC; Hawkins DA; Gazzard BG; HIV/GUM Unit, St Stephen's Clinic, Westminster Hospital, London,; UK.; OBJECTIVE: To study the incidence, clinical features, treatment and outcome of patients with Salmonella, Shigella or Campylobacter infection. DESIGN: Retrospective analysis. SETTING: Two dedicated HIV units within a London teaching hospital. METHODS: All patients with Salmonella, Shigella or Campylobacter infection we
Visceral leishmaniasis in HIV-1-infected individuals: a common opportunistic infection in Spain?: AIDS. 1992 Dec;6(12):1499-503. Unique Identifier : AIDSLINE MED/93152036; Medrano FJ; Hernandez-Quero J; Jimenez E; Pineda JA; Rivero A; Sanchez-Quijano A; Velez ID; Viciana P; Castillo R; Reyes MJ; et al; Viral Hepatitis and AIDS Study Group, Virgen del Rocio University; Hospital, Sevilla, Spain.; OBJECTIVE: To investigate the epidemiological, clinical and biological features of visceral leishmaniasis (VL) in patients with HIV-1 infection. DESIGN: Retrospective study. SETTING: Three university hospitals in southern Spain . PATIENTS: Forty-seven adult patients with VL and HIV-1
A defect in tissue factor expression in monocytes from patients infected by HIV correlates with markers of disease progression.: AIDS. 1992 Dec;6(12):1542-4. Unique Identifier : AIDSLINE MED/93152043; Lathey JL; Agosti JM; Spector SD
Bone-marrow diagnosis of opportunistic infections in HIV disease [letter]: AIDS. 1992 Dec;6(12):1559-60. Unique Identifier : AIDSLINE MED/93152056; Costello C; Rule S; Shanson D; Mir N
CD4 lymphocyte decline and survival in human immunodeficiency virus infection. The Military Medical Consortium for Applied Retroviral Research.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):2039-47. Unique Identifier : AIDSLINE MED/93152277; Drabick JJ; Williams WJ; Tang DB; Sun W; Chung RC; Department of Bacterial Diseases, Walter Reed Army Institute of; Research, Washington, DC 20307-5100.; The loss of the CD4 lymphocyte is the central pathophysiologic event in the progression of human immunodeficiency virus (HIV) infection. This retrospective study, based on review of data from deceased HIV patients followed in a single HIV clinic, was conducted to determine if the rate of CD4 lymphocyte decline was pre
Demonstration of HTLV-related proviral DNA sequences and antibodies reactive with HTLV internal proteins in an Hungarian patient with Sezary syndrome.: Leuk Lymphoma. 1992 Aug;7(5-6):511-5. Unique Identifier : AIDSLINE MED/93153345; Kiss J; Kiss A; Toth FD; Suranyi P; Szegedi A; Rak K; Institute of Microbiology, University Medical School, Debrecen,; Hungary.; DNA sequences distantly related to the proviral DNA of HTLV-I were found in the leukemic cells of a Hungarian patient suffering from Sezary syndrome. Serum samples from the patient contained antibodies reactive with the internal core polypeptides of HTLV-I and HTLV-II, but not with the env gene encoded type-specific H
Disposition of the human immunodeficiency virus Tat inhibitor, Ro 5-3335, in rats and dogs.: Drug Metab Dispos. 1992 Nov-Dec;20(6):954-7. Unique Identifier : AIDSLINE MED/93154223; Town C; Chang D; Henderson L; Garland WA; Department of Drug Metabolism, Hoffmann-La Roche, Inc., Nutley,; NJ 07110.
The systemic availability of oral glutathione.: Eur J Clin Pharmacol. 1992;43(6):667-9. Unique Identifier : AIDSLINE MED/93154421; Witschi A; Reddy S; Stofer B; Lauterburg BH; Department of Clinical Pharmacology, University of Bern,; Switzerland.; When the plasma glutathione concentration is low, such as in patients with HIV infection, alcoholics, and patients with cirrhosis, increasing the availability of circulating glutathione by oral administration might be of therapeutic benefit. To assess the feasibility of supplementing oral glutathione we have determine
Feline Immunodeficiency Virus. Proceedings of an international conference. Davis, California, 4-7 September 1991.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):1-224. Unique Identifier : AIDSLINE MED/93158172
Effect of primary phase feline immunodeficiency virus infection on cats with chronic toxoplasmosis.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):121-31. Unique Identifier : AIDSLINE MED/93158173; Lappin MR; Gasper PW; Rose BJ; Powell CC; Department of Clinical Sciences, College of Veterinary Medicine; and Biomedical Sciences, Colorado State University, Fort Collins; 80523.; The effect of primary phase feline immunodeficiency virus (FIV) infection on clinical signs, hematological values, Toxoplasma gondii oocyst shedding, T. gondii-specific serology, T. gondii-specific cell-mediated immune responses, non-specific cell-mediated immune responses, and lymphocyte subpopulations from cats with
Use of two virustatica (AZT, PMEA) in the treatment of FIV and of FeLV seropositive cats with clinical symptoms.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):167-75. Unique Identifier : AIDSLINE MED/93158178; Hartmann K; Donath A; Beer B; Egberink HF; Horzinek MC; Lutz H; Hoffmann-Fezer G; Thum I; Thefeld S; I. Department of Veterinary Medicine,; Ludwig-Maximilians-University, Munich, Germany.; In the present study the therapeutic efficacy and the side effects of two antiretroviral compounds used in human acquired immunodeficiency syndrome (AIDS) research, 3 -azido-2 ,3 -dideoxythymidine ( AZT , zidovudine, Retrovir) and 9-(2-phosphonylmethoxy
Immunization-induced decrease of the CD4+:CD8+ ratio in cats experimentally infected with feline immunodeficiency virus.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):199-214. Unique Identifier : AIDSLINE MED/93158181; Lehmann R; von Beust B; Niederer E; Condrau MA; Fierz W; Aubert A; Ackley CD; Cooper MD; Tompkins MB; Lutz H; Department of Veterinary Medicine, University of Zurich,; Switzerland.; In a previous experiment a group of 15 specified pathogen free (SPF) cats were experimentally infected with a Swiss isolate of feline immunodeficiency virus (FIV). A group of 15 SPF cats served as FIV negative controls. Nine cats of each group were vaccinated with a recombinant feline leukemia virus (FeLV) vaccine, si
Persistent upregulation of MHC class II antigen expression on T-lymphocytes from cats experimentally infected with feline immunodeficiency virus.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):71-81. Unique Identifier : AIDSLINE MED/93158188; Rideout BA; Moore PF; Pedersen NC; Department of Medicine, School of Veterinary Medicine, University; of California, Davis 95616.; A significant elevation in the percentage of CD4+ and CD8+ T-lymphocytes expressing major histocompatibility complex (MHC) Class II antigens was observed in the blood of cats shortly after they were experimentally infected with feline immunodeficiency virus (FIV). In addition to an increase in the relative proportion
Interaction of acute feline herpesvirus-1 and chronic feline immunodeficiency virus infections in experimentally infected specific pathogen free cats.: Vet Immunol Immunopathol. 1992 Dec;35(1-2):95-119. Unique Identifier : AIDSLINE MED/93158190; Reubel GH; George JW; Barlough JE; Higgins J; Grant CK; Pedersen NC; Department of Medicine, School of Veterinary Medicine, University; of California, Davis 95616.; Cats with or without chronic feline immunodeficiency virus (FIV) infection were exposed to feline herpesvirus, type 1 (FHV-1). FIV infected cats became sicker than non-FIV infected cats and required more supportive treatment. However, there were no differences in the length of their illness or in the levels and durati
Pancytopaenia and hepatosplenomegaly in an AIDS patient responding to high dose steroids [letter]: Int J STD AIDS. 1992 Nov-Dec;3(6):450-1. Unique Identifier : AIDSLINE MED/93160315; Aitken C; Dalgleish A; Salama A; Forster G
The mechanisms and risks of surgical glove perforation.: J Hosp Infect. 1992 Dec;22(4):279-86. Unique Identifier : AIDSLINE MED/93163528; Palmer JD; Rickett JW; Department of Surgery, Torbay Hospital, Devon, UK.; Intact surgical gloves are a barrier to hepatitis B virus and human immunodeficiency virus (HIV) but once perforated during surgery they cannot sustain adequate defence. This study examines the rate of glove perforations during surgery at a District General Hospital. In total, 275 pairs of gloves were collected from 1
Efficient and reproducible new semimicromethod for the detection and titration of HIV in human plasma.: J Med Virol. 1992 Nov;38(3):207-13. Unique Identifier : AIDSLINE MED/93163777; Andreoni M; Sarmati L; Parisi SG; Ercoli L; Rocchi G; Department of Public Health and Cellular Biology, University of; Rome Tor Vergata, Italy.; A semimicromethod was established for isolating human immunodeficiency virus (HIV) in plasma using 48-well plates and a pool of peripheral blood mononuclear cells (PBMC) from several donors as targets for infection, which increases the efficiency of isolation by reducing the effect of variability due to diverse donor
[8th World Congress AIDS (news)]: TVZ. 1992 Nov 26;(22):807-8. Unique Identifier : AIDSLINE MED/93168309; Hoeksema K
Herpes esophagitis: a cause of upper gastrointestinal bleeding in an immunocompetent patient.: J Formos Med Assoc. 1992 Nov;91(11):1112-4. Unique Identifier : AIDSLINE MED/93169135; Chien RN; Chen PC; Lin PY; Wu CS; Department of Hepato-Gastroenterology, Chang Gung Memorial; Hospital, Taipei, Taiwan, R.O.C.; Herpes esophagitis presents as dysphagia and odynophagia in the majority of cases. Rarely has hematemesis been reported. We report a case of herpes esophagitis presenting with hematemesis in an immunocompetent patient. This 67-year-old man suffered from herpes esophagitis, proven by a panendoscopic examination, with c
Quantitative analysis of immunocompetent cells in human periapical lesions: correlations with clinical findings of the involved teeth.: J Endod. 1992 Oct;18(10):497-500. Unique Identifier : AIDSLINE MED/93171771; Matsuo T; Ebisu S; Shimabukuro Y; Ohtake T; Okada H; Department of Conservative Dentistry, Tokushima University School; of Dentistry, Japan.; Human periapical lesions develop as a result of a pathological immune response to continuous stimuli from infected root canals. This study identified the immunocompetent cells in such lesions immunohistochemically and quantified them to examine their interrelationships and correlations with clinical findings. The numb
Role of CD8+ in late opportunistic infections of patients with AIDS.: Res Immunol. 1992 Nov-Dec;143(9):903-7. Unique Identifier : AIDSLINE MED/93174093; Fiala M; Kermani V; Gornbein J; Department of Neurology, UCLA Medical Center 90024-1747.; We studied the relationship of CD4+ and CD8+ depletion to initial and late opportunistic infections in 62 patients with AIDS. The mean interval between initial and late infections was 12.2 months. Geometric mean (and 95% confidence intervals) of T-cell counts at the diagnosis of each infection were: (Pneumocystis cari
Monoclonal antibodies to the extracellular domain of HIV-1IIIB gp160 that neutralize infectivity, block binding to CD4, and react with diverse isolates.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1875-85. Unique Identifier : AIDSLINE MED/93143997; Nakamura GR; Byrn R; Rosenthal K; Porter JP; Hobbs MR; Riddle L; Eastman DJ; Dowbenko D; Gregory T; Fendly BM; et al; Department of Immunobiology, Genentech, Inc., S. San Francisco,; CA 94080.; Ten monoclonal antibodies prepared against a soluble, recombinant form of gp160, derived from the IIIB isolate of HIV-1, were characterized. Four of the antibodies neutralized HIV-1IIIB infectivity in vitro, three blocked the binding of recombinant gp120 to CD4, three were reactive with gp41, and one preferentially re
Inactivation of the human immunodeficiency virus by hypericin: evidence for photochemical alterations of p24 and a block in uncoating.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1929-36. Unique Identifier : AIDSLINE MED/93144002; Degar S; Prince AM; Pascual D; Lavie G; Levin B; Mazur Y; Lavie D; Ehrlich LS; Carter C; Meruelo D; Department of Pathology, New York University Medical Center, NY; 10016.; Following attachment and entry of human immunodeficiency virus (HIV) into a host cell, the HIV genomic RNA is reverse transcribed to cDNA. This step may be inhibited by hypericin, a compound that induces alterations of the retroviral capsid. Incubation of HIV with hypericin rendered the virus noninfectious. The replic
HIV-1 reverse transcriptase inhibitor from Phyllanthus niruri.: AIDS Res Hum Retroviruses. 1992 Nov;8(11):1937-44. Unique Identifier : AIDSLINE MED/93144003; Ogata T; Higuchi H; Mochida S; Matsumoto H; Kato A; Endo T; Kaji A; Kaji H; Research Institute for Molecular Genetics, Tsumura & Co.,; Ibaraki-Ken, Japan.; An aqueous extract of Phyllanthus niruri (Euphorbiaceae) inhibited human immunodeficiency virus type-1 reverse transcriptase (HIV-1-RT). The inhibitor against HIV-1-RT in this plant was purified by combination of three column chromatographies, Sephadex LH-20, cellulose, and reverse-phase high-performance liquid chroma
Treatment of AIDS-related non-Hodgkin's lymphoma with a twelve week chemotherapy program.: Leuk Lymphoma. 1992 Oct;8(3):213-20. Unique Identifier : AIDSLINE MED/93145022; Sawka CA; Shepherd FA; Brandwein J; Burkes RL; Sutton DM; Warner E; Division of Medical Oncology, Toronto-Bayview Regional Cancer; Centre, Ontario, Canada.; Current treatment options for acquired-immunodeficiency syndrome (AIDS)-related non-Hodgkin s lymphoma (NHL) are unsatisfactory because of excessive toxicity rates and frequent recurrence of lymphoma. In this phase II study, we evaluated a novel 12 week chemotherapy program with re
Endogenous interferon plasma levels and antipyrine pharmacokinetics in patients with viral infections.: Int J Clin Pharmacol Ther Toxicol. 1992 Nov;30(11):530-3. Unique Identifier : AIDSLINE MED/93146723; Brockmeyer NH; Mertins L; Spatz D; Tillmann I; Goos M; Department of Dermatology, University of Essen, Germany.; We investigated the pharmacokinetics of antipyrine and the endogenous plasma levels of interferon alpha (IFN alpha), interferon beta (IFN beta) and interferon gamma (IFN gamma) in 10 otherwise healthy volunteers before outbreak (baseline) and in the symptomatic interval of an acute viral respiratory infection, and als
Phorbol ester induces down-regulation of CD4 molecule expression and resistance to in vitro infection by HIV1.: Thymus. 1992 Dec;20(4):239-48. Unique Identifier : AIDSLINE MED/93150540; Touraine JL; Sanhadji K; Benard I; Research Laboratory on Transplantation, Immunobiology and; Retrovirology, INSERM U80, CNRS URA 1177, Universite Claude; Bernard, Hopital Edouard Herriot, Lyon, France.; In vitro infectivity of the MT4 lymphoid cell line with human immunodeficiency virus (HIV) has been studied in correlation with the degree of expression of the CD4 molecule at the cell surface. To modulate this CD4 expression in vitro, pre-incubation with phorbol myristate acetate (PMA) was used. The lowest CD4 expres
Rifamycins as inhibitors of retroviral reverse transcriptase from M-MuLV, RAV-2, and HIV-1.: Farmaco. 1992 Nov;47(11):1367-83. Unique Identifier : AIDSLINE MED/93151956; Bartolucci C; Cellai L; Di Filippo P; Segre A; Brufani M; Filocamo L; Bianco AD; Guiso M; Brizzi V; Benedetto A; et al; Istituto di Strutturistica Chimica, G. Giacomello, CNR C.P. 10; 00016, Roma, Italy.; 29 Rifamycins were tested for inhibition of Reverse Transcriptase (RT) as potential anti HIV drugs. Two purified commercial enzymes from M-MuLV and RAV-2 were used. Anti-RT activity was also measured on a crude lysate of HIV-1. The results show that some derivatives have interesting levels of activity on isolated M-Mu
Mapping of two new human B-cell epitopes on HIV-1 gp120.: AIDS. 1992 Dec;6(12):1451-6. Unique Identifier : AIDSLINE MED/93152028; Kusk P; Holmback K; Lindhardt BO; Hulgaard EF; Bugge TH; State Serum Institute, Department of Virology, Copenhagen,; Denmark.; OBJECTIVE: To map epitopes on gp120 defined by human antibodies and to examine the neutralizing activity of these antibodies. DESIGN AND METHODS: Serum from HIV-1-antibody-positive individuals was used to screen a random fragment expression library representing gp120 from the HIVIIIB clone BH10. The library was based
The safety and pharmacokinetics of a reverse transcriptase inhibitor, 3TC, in patients with HIV infection: a phase I study.: AIDS. 1992 Dec;6(12):1471-5. Unique Identifier : AIDSLINE MED/93152031; van Leeuwen R; Lange JM; Hussey EK; Donn KH; Hall ST; Harker AJ; Jonker P; Danner SA; Department of Internal Medicine (AIDS Unit), Academic Medical; Centre, University of Amsterdam, The Netherlands.; OBJECTIVE: To determine the safety and pharmacokinetics of the nucleoside analogue, 3TC . DESIGN: A Phase I, open-label, single-centre study. METHODS: Twenty asymptomatic, HIV-infected male patients with CD4 lymphocyte counts
Adriamycin, bleomycin and vincristine chemotherapy with recombinant granulocyte-macrophage colony-stimulating factor in the treatment of AIDS-related Kaposi's sarcoma.: AIDS. 1992 Dec;6(12):1477-81. Unique Identifier : AIDSLINE MED/93152032; Gill PS; Bernstein-Singer M; Espina BM; Rarick M; Magy F; Montgomery T; Berry MS; Levine A; Department of Internal Medicine, University of Southern; California School of Medicine, Los Angeles.; OBJECTIVE: To determine the maximum tolerated dose of granulocyte-macrophage colony-stimulating factor (GM-CSF) that would reduce the severity and duration of neutropenia from combination cytotoxic chemotherapy in the treatment of AIDS-related Kaposi s sarcoma (KS). DESIGN: Phase I, dose escalation. SETTING: Outpatien
AIDS-associated mucocutaneous Kaposi's sarcoma treated with bleomycin.: AIDS. 1992 Dec;6(12):1483-7. Unique Identifier : AIDSLINE MED/93152033; Caumes E; Guermonprez G; Katlama C; Gentilini M; Departement de Medecine Tropicale, Maladies Infectieuses,; Parasitologie, Mycologie et Sante Publique, Hopital de la; Salpetriere, Paris, France.; OBJECTIVES: To evaluate efficacy and tolerance of bleomycin in AIDS-associated mucocutaneous Kaposi s sarcoma. A previous study showed that bleomycin was effective and well tolerated in this setting. DESIGN: A non-comparative, open, prospective study. METHODS: Seventy patients were treated with 5 mg per day intramuscu
Identification of cross-reactive epitopes recognized by HIV-1 false-positive sera [letter]: AIDS. 1992 Dec;6(12):1547-8. Unique Identifier : AIDSLINE MED/93152046; Langedijk JP; Vos WF; van Doornum GJ; Rotman HA; Meloen RH; Huisman JG
Antibody epitopes sensitive to the state of human immunodeficiency virus type 1 gp41 oligomerization map to a putative alpha-helical region.: AIDS Res Hum Retroviruses. 1992 Dec;8(12):2055-62. Unique Identifier : AIDSLINE MED/93152279; Poumbourios P; McPhee DA; Kemp BE; St. Vincent's Institute of Medical Research, Fitzroy, VIC,; Australia.; Two antibodies, affinity-purified from human immunodeficiency virus-positive human plasma with synthetic peptides in the region gp41(566-596), were found to recognize oligomeric gp41 more strongly than the monomeric form in an immunoblot assay. In contrast, a murine anti-gp160 monoclonal antibody, which maps within th
Automated multiple peptide synthesis.: Pept Res. 1992 Nov-Dec;5(6):315-20. Unique Identifier : AIDSLINE MED/93153136; Gausepohl H; Boulin C; Kraft M; Frank RW; ABIMED Analysen-Technik GmbH, FRG.; A fully automated instrument for multiple simultaneous peptide synthesis was constructed to provide large numbers of peptides for immunological research. The synthesis is performed in a flow-through mode with the conventional solid supports contained in 48 individual reaction columns. The instrument is based on a comm
Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices.: Drug Metab Dispos. 1992 Nov-Dec;20(6):869-76. Unique Identifier : AIDSLINE MED/93154210; Balani SK; Pitzenberger SM; Kauffman LR; Arison BH; Ramjit HG; Goldman ME; O'Brien JA; King JD; Hoffman JM; Rooney CS; et al; Department of Animal and Exploratory Drug Metabolism, Merck; Research Laboratories, West Point, PA 19486.; L-696,229 is a potent and specific inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and is currently undergoing clinical evaluation. In vivo metabolism in rats was investigated using an intravenous bolus dose of 5 mg/kg [3H]L-696,229. The amount of radioactivity eliminated in bile and uri
The use of GM-CSF in AIDS.: Infection. 1992;20 Suppl 2:S103-6. Unique Identifier : AIDSLINE MED/93154804; Scadden DT; Dept. of Medicine, New England Deaconess Hospital, Harvard; Medical School, Boston, MA.; Hematopoietic growth factors may mitigate the cytopenias that frequently complicate HIV disease or its treatment. Clinical and in vitro studies have indicated the ability of granulocyte-macrophage colony-stimulating factor (GM-CSF), granulocyte colony-stimulating factor (G-CSF) or erythropoietin (EPO) to overcome the
Acquired immunodeficiency syndrome: education exposure, knowledge and attitude of Nigerian adolescents in Calabar.: Ann Trop Paediatr. 1992;12(4):397-402. Unique Identifier : AIDSLINE MED/93159112; Asindi AA; Ibia EO; Young MU; Department of Paediatrics, University of Calabar Teaching; Hospital, Nigeria.; The knowledge of and attitude to acquired immunodeficiency syndrome (AIDS) of 738 secondary school youths in Calabar were studied by questionnaire in March 1991. Most (92%) of the adolescents had heard about AIDS, largely through the mass media (79-85%), with parents and teachers contributing in less than 40%. About 3
Mycobacterium malmoense type II bacteraemia contributing to death in a patient with AIDS.: Int J STD AIDS. 1992 Nov-Dec;3(6):445-6. Unique Identifier : AIDSLINE MED/93160311; Cowling P; Glover S; Reeves DS; Department of Medical Microbiology, Southmead Hospital,; Westbury-on-Trym, Bristol, UK.
[Behavioral characteristics of homo- and bisexuality affecting the prevalence of HIV infection]: Vestn Ross Akad Med Nauk. 1992;(9-10):11-3. Unique Identifier : AIDSLINE MED/93160824; Eramova IIu; Pokrovskii VV
[Clinico-epidemiological analysis of the cases of HIV infection in the north-western region of Russia]: Vestn Ross Akad Med Nauk. 1992;(9-10):13-6. Unique Identifier : AIDSLINE MED/93160825; Vlasov NN; Smol'skaia TT; Noskov FS; Mebel' BD; The paper provides an epidemiological characterization of HIV infection spread in a Russia s large region with more than 10 million people. The epidemiological findings show that the significant onset of HIV infection occurred among the population in this region in mid 1988. Homosexuals and bisexuals are prevalent amo
[Clinical manifestations and the problems of classification of HIV infection]: Vestn Ross Akad Med Nauk. 1992;(9-10):16-9. Unique Identifier : AIDSLINE MED/93160826; Iurin OG; Irova TI; Gabrilovich DI; Suvorova ZK; Kravchenko AV; Potekaev NS; Kharchenko OI; Pokrovskii VV; The clinical manifestations and some immunological parameters (CD4 lymphocytes, CD4/CD8 ratio, IgM, IgA, IgG levels, skin test) were examined in 226 adult patients (148 males and 78 females) infected with HIV. These included 58 (26%) asymptomatic patients with seropositive test, 109 (48%) with the only clinical manife
[Hemostatic disorders in patients with HIV infection]: Vestn Ross Akad Med Nauk. 1992;(9-10):19-21. Unique Identifier : AIDSLINE MED/93160827; Kravchenko AV; Poliakova AM; Iurin OG; Astrina OS; Pokrovskii VV; Impaired hemostasis was studied in 50 adult patients with HIV infection. The blood coagulative potential, the number and functional activity of platelets were examined. Platelet aggregation and secretion were shown to change earlier than thrombocytopenia developed and clinical signs of HIV infection appeared. The dist
[Immunologic changes in the process of the treatment of children with HIV infection using azidothymidine]: Vestn Ross Akad Med Nauk. 1992;(9-10):21-4. Unique Identifier : AIDSLINE MED/93160828; Gabrilovich DI; Irova TI; Kuznetsova VV; Khabarova VV; Serebrovskaia LV; Pokrovskii VV
[HIV infection: a case of progressive encephalopathy and Pneumocystis carinii pneumonia in a child]: Vestn Ross Akad Med Nauk. 1992;(9-10):24-8. Unique Identifier : AIDSLINE MED/93160829; Irova TI; kiparisov EL; Kuznetsova VV; Lobanov AS; Pokrovskii VV
[Pneumocystis carinii infection in a HIV infection department]: Vestn Ross Akad Med Nauk. 1992;(9-10):28-30. Unique Identifier : AIDSLINE MED/93160830; Ermak TN; Ivanenko IP; Makarova NIu; Novozhenina EB; Pokrovskii VV; To determine the prevalence of Pneumocystis carinii in the HIV-infection department, a simultaneous survey was made of 33 HIV-infected patients at various stages of the disease, of close relatives that were nursing the patients in the unit (n-7), and of medical staff of the department (n-20). Patients with toxic infec
[AIDS--the global problem of the century. Prospects of the development of AIDS research]: Vestn Ross Akad Med Nauk. 1992;(9-10):3-8. Unique Identifier : AIDSLINE MED/93160831; Pokrovskii VI; Andzhaparidze OG; Uryvaev LV; Reshetnikova LN
[Clinico-experimental study of mental processes in men with HIV infection]: Vestn Ross Akad Med Nauk. 1992;(9-10):31-2. Unique Identifier : AIDSLINE MED/93160832; Beliaeva VV; Semenovich AV; Ruchkina EV; Pokrovskii VV; A total of 55 males aged 19.5 to 62 years who were infected with HIV were examined psychopathologically+ and neuropsychologically by A.R. Luria s methods. Twenty-one of these patients were homosexuals. Syphilis was recorded in 34.7% in this group. Lymphadenopathy was the major clinical sign of HIV infection. Symptoms
[Comparative analysis of functional activity of peripheral blood phagocytes in HIV-infected patients and in those with recurrent herpes simplex]: Vestn Ross Akad Med Nauk. 1992;(9-10):32-6. Unique Identifier : AIDSLINE MED/93160833; Pinegin BV; Butakov AA; Buraia TL; Saidov MZ; Makarova SA; Alkeeva AB; The functional activity of peripheral phagocytes were comparatively studied in 14 HIV-infected patients and 28 patients with chronic Herpes simplex viral infection. The two groups exhibited lowered adhesive capacity of phagocytes, impaired production and excretion of active oxygen metabolites. In addition, the patient
[Tumor necrosis factor-alpha and interleukin-1beta in the blood plasma of patients with HIV infection]: Vestn Ross Akad Med Nauk. 1992;(9-10):36-41. Unique Identifier : AIDSLINE MED/93160834; Ketlinskii SA; Kalinina NM; Tsvetkova SN; Rakhmanova AG; Maslov VN; Khaldeeva NA; The paper presents examination findings of 67 HIV-infected patients: 32 children aged 2.5 to 16 years and 35 adults aged 21 to 46 years. The proportion of patients with higher alpha-tumor necrosis factor and interleukin-1 beta increased with progression of the disease, the two parameters being higher in the children t
[Detection of Mycoplasma and its antibodies in the blood of HIV-positive patients and in healthy persons]: Vestn Ross Akad Med Nauk. 1992;(9-10):41-3. Unique Identifier : AIDSLINE MED/93160835; Rakovskaia IV; Goncharova SA; Sarkisian NA; Miller GG; The comparative study of HIV-positive and clinically healthy persons has indicated that the antigens of M. pneumoniae, M. fermentans and U. urealyticum are encountered nearly twice more frequently in the blood of HIV-infected patients than in that of healthy individuals. Mycoplasma antibodies are detected in HIV-posit
[The immunoenzyme test system for detection of HIV-1 antigens based on using immune polyclonal anti-HIV serum and monoclonal antibodies against gene GAG HIV-1 proteins]: Vestn Ross Akad Med Nauk. 1992;(9-10):43-7. Unique Identifier : AIDSLINE MED/93160836; Trushinskaia GN; Simonov VI; Makarova NE; Nosik DN; Kushch AA; Gibadulin RA; The paper describes the enzyme immunoassay system for detection of human immunodeficiency virus antigens, which is based on the use of rabbit anti-HIV antibodies and monoclonal antibodies to HIV-1 gene proteins gag. The system may be useful in the examination of laboratory and clinical samples to reveal both free and
[Peptides from the principal neutralizing and CD4-binding domain: similar immunoreactive properties and structure pattern]: Vestn Ross Akad Med Nauk. 1992;(9-10):47-52. Unique Identifier : AIDSLINE MED/93160837; Meshcheriakova DV; Andreev SM; Sidorova MV; Vafina MG; Az'muko AA; Petrukhina AO; Khaitov RM; The human immunodeficiency virus (HIV) proteins gp120 and gp41 are the principal immune target in HIV infection. One of the most important trends in the study of AIDS is linked to the mapping of sites involving in the binding to the cell receptor CD4 and in the induction of virus-neutralizing antibodies (VNA). Recent
[Expression of HIV-1 tat gene under the control of P 7,5 KD vaccinia virus promoter in CV-1 cells]: Vestn Ross Akad Med Nauk. 1992;(9-10):52-5. Unique Identifier : AIDSLINE MED/93160838; Kholodkov OA; Fodor II; The transient expression of the HIV-1 gag genes and a HIV-1 ++trans-activator protein (tat)-encoded was made in cultured CV-1 cells. In recombinant plasmids, the gag gene was under the control of HIV-1 ++trans-activator sequence (tar) and the tat gene was under the control of a 7.5-kd vaccinia promoter. Transactivatio
[Study of antigenic structure of HIV-1 protein p24 using monoclonal antibodies]: Vestn Ross Akad Med Nauk. 1992;(9-10):55-9. Unique Identifier : AIDSLINE MED/93160839; Konovalov EE; Loktev VB; Pokrovskii AG; Fediuk NV; Chernykh AI; Nechaev IuS; Kuliandin SA; Kipriianov SM; Ofitserov VI; During the experiments 4 murine and 3 rat hybridomas producing monoclonal antibodies (MAb) against the protein p24 of human immunodeficiency virus type 1 (HIV-1) have been obtained. Using the immunoblotting technique, it was established that all the species of MAb reacted with the same viral proteins which are derivat
[Persistent viruses in serological diagnosis of HIV infection]: Vestn Ross Akad Med Nauk. 1992;(9-10):59-62. Unique Identifier : AIDSLINE MED/93160840; Khaitov RM; Glushchenko MV; Trubcheninova LP; Prokopenko VD; Specific antibodies to persistent viruses ( CMV , EBV, HBV) were detected by ELISA in groups of HIV-infected patients and persons showing indefinite results of the immunoblotting test for HIV-1 antigens, on the one hand, and in HIV-seronegative donors and patients
[Epidemiology of HIV infection and the organization of anti- epidemiologic measures in the USSR 1987-1991]: Vestn Ross Akad Med Nauk. 1992;(9-10):8-11. Unique Identifier : AIDSLINE MED/93160841; Pokrovskii VV; Savchenko IG; Suvorova ZK; Buravtsova EV; Pankova GIu; Arzamastsev VP; Bochkov AD
Virus-like particles with reverse transcriptase activity associated with Kawasaki disease.: J Med Virol. 1992 Nov;38(3):175-82. Unique Identifier : AIDSLINE MED/93163772; Lin CY; Chen IC; Cheng TI; Liu WT; Hwang B; Chiang BN; Department of Medical Research, Veterans General Hospital-Taipei,; Taiwan, Republic of China.; To investigate the etiologic agent associated with Kawasaki disease (KD), we initially established a cocultivation system using concanavalin A (Con A)-stimulated lymphoblastoid cells obtained from each retrovirus-seronegative individual s peripheral blood mononuclear cells (MNCs) cocultivated with each of 1) 40 patien
Infectious diseases in dentistry: answers to ten legal (or illegal?) questions.: J Calif Dent Assoc. 1992 Oct;20(10):27-30. Unique Identifier : AIDSLINE MED/93172001; Logan MK
Inhibitory effects of 2'-deoxy-5-styryluridine 5'-triphosphate analogs on retroviral reverse transcriptase and eukaryotic DNA polymerases.: Nucleic Acids Symp Ser. 1992;(27):191-2. Unique Identifier : AIDSLINE MED/93173645; Yamaguchi T; Izuta S; Suzuki M; Yoshida S; Matsukage A; Saneyoshi M; Department of Biological Sciences, Nishi-Tokyo University,; Yamanashi, Japan.; Some sugar modified analogs of 2 -deoxy-E-5-styryluridine triphosphates were synthesized and examined for their inhibitory effects on eukaryotic DNA polymerases and HIV-1 reverse transcriptase. Among these compounds, 3 -azido-2 ,3 -dideoxy-E-5-styrylUTP (6) and 2 ,3 -dideoxy-E-5-styrylUTP (7) showed remarkable inhibit
Immunohistochemical detection of double-stranded-RNA-dependent protein kinase (p68) with a novel monoclonal antibody TJ4C4. A case report of an AIDS-associated Kaposi's sarcoma treated with alpha-interferon.: Tumour Biol. 1992;13(5-6):324-9. Unique Identifier : AIDSLINE MED/93174154; Haines GK; Ghadge GD; Combs SG; Leslie W; Thimmappaya B; Radosevich JA; Department of Pathology, Northwestern University/VA Lakeside; Medical Center, Chicago, Ill.; Double-stranded RNA (dsRNA)-dependent protein kinase (p68) has been shown to be induced by alpha-interferon (IFN-alpha) in mammalian cells. It binds to dsRNA, and is believed to be a factor in the control of both cellular and viral protein synthesis. This report describes the use of a new monoclonal antibody (MAb) TJ4
Use of oil overlays in oil-free PCR technology.: Biotechniques. 1993 Jan;14(1):36-40. Unique Identifier : AIDSLINE MED/93143950; Katzman M; Dept. of Medicine, Pennsylvania State University, College of; Medicine, Milton S. Hershey Medical Center, Hershey 17033.
Quantitative competitive polymerase chain reaction for accurate quantitation of HIV DNA and RNA species.: Biotechniques. 1993 Jan;14(1):70-81. Unique Identifier : AIDSLINE MED/93143958; Piatak M Jr; Luk KC; Williams B; Lifson JD; Division of HIV and Exploratory Research, Genelabs Incorporated,; Redwood City, CA 94063.; Inherent features of the PCR make this procedure suboptimal for quantitative applications. For typical clinical specimens, the absolute amount of product derived from PCR does not always bear a consistent relationship to the amount of target sequence present at the start of the reaction. Competitive PCR approaches to
Structural features of an RNA containing the CUGGGA loop of the human immunodeficiency virus type 1 trans-activation response element.: Biochemistry. 1993 Feb 2;32(4):1105-12. Unique Identifier : AIDSLINE MED/93144314; Colvin RA; White SW; Garcia-Blanco MA; Hoffman DW; Department of Microbiology, Duke University Medical Center,; Durham, North Carolina 27710.; A 19-nucleotide RNA containing the CUGGGA loop sequence corresponding to nucleotides 30-35 of the HIV-1 trans-activation response element (TAR) was synthesized in vitro and analyzed by biochemical methods and one- and two-dimensional NMR spectroscopy. Diagnostic RNase cleavage patterns were similar for the loops in th
Intravenous drug use, methadone, and AIDS: ask not for whom the bell tolls [editorial] [published erratum appears in J Addict Dis 1993;12(2):preceding 1]: J Addict Dis. 1993;12(1):1-5. Unique Identifier : AIDSLINE MED/93144354; Stimmel B
Immunodeficiency diseases.: Immunol Ser. 1993;58:543-77. Unique Identifier : AIDSLINE MED/93144442; Virella G; Department of Microbiology and Immunology, Medical University of; South Carolina, Charleston.
Clinical perspectives in the treatment of HIV disease: the role of didanosine. Introduction.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S1. Unique Identifier : AIDSLINE MED/93144543; Corey L; University of Washington School of Medicine, Seattle, Washington.
Clinical perspectives in the treatment of HIV disease: the role of didanosine. Chicago, Illinois, 28 September 1991.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S1-73. Unique Identifier : AIDSLINE MED/93144544
In vitro antiviral activity of didanosine compared with that of other dideoxynucleoside analogs against laboratory strains and clinical isolates of human immunodeficiency virus.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S16-21. Unique Identifier : AIDSLINE MED/93144545; Hitchcock MJ; Pharmaceutical Research Institute, Bristol-Myers Squibb Company,; Wallingford, Connecticut 06492.; The in vitro activity of didanosine (2 ,3 -dideoxyinosine, ddI) against the human immunodeficiency virus (HIV) is generally less potent than that of zidovudine (3 -azidothymidine, AZT ) and zalcitabine (2 ,3 -dideoxycytidine,
Longitudinal analysis of responses to oral didanosine therapy following zidovudine therapy in advanced infection with human immunodeficiency virus.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S32-9. Unique Identifier : AIDSLINE MED/93144549; McLaren C; Rozencweig M; Beltangady M; Nicaise C; Yarchoan R; Dolin R; Allan JD; Cooley TP; Seidlin M; Smaldone LF; Bristol-Myers Squibb Pharmaceutical Research Institute,; Wallingford, Connecticut 06492-7660.; The effect on immunologic and virological parameters of up to 24 weeks of therapy with didanosine at daily oral doses of
Long-term follow-up of didanosine administered orally twice daily to patients with advanced human immunodeficiency virus infection and hematologic intolerance of zidovudine.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S46-51. Unique Identifier : AIDSLINE MED/93144551; Allan JD; Connolly KJ; Fitch H; Jackson-Pope L; McLaren C; Canetta R; Groopman JE; New England Deaconess Hospital, Division of Infectious Diseases,; Boston, Massachusetts 02215.; This phase 1 trial was conducted to evaluate the safety and tolerance of didanosine (ddI) in subjects with AIDS or AIDS-related complex (ARC) who previously had demonstrated hematologic intolerance of zidovudine. Thirty subjects, 21 with AIDS and nine with ARC, were enrolled. Initially, didanosine was administered ora
The didanosine Expanded Access Program: safety analysis.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S63-8. Unique Identifier : AIDSLINE MED/93144554; Pike IM; Nicaise C; Bristol-Myers Oncology Division, Princeton, New Jersey; 08543-4500.; The didanosine Expanded Access Program was designed by the Bristol-Myers Squibb Company (Princeton, NJ) to provide didanosine for treatment of patients who could not be enrolled in clinical trials. This program consisted of two protocols: a treatment IND (investigational new drug) prot
Nucleoside analogs: similarities and differences.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S7-15. Unique Identifier : AIDSLINE MED/93144556; Sommadossi JP; Department of Pharmacology, University of Alabama, Birmingham; 35294.; Among the steps in the replication cycle of human immunodeficiency virus (HIV) that are potential targets for antiviral chemotherapy, the viral DNA polymerase or reverse transcriptase has been a target of choice in research on anti-HIV drugs. Nucleoside analogs--the agents studied in relation to this target--have no i
[Pulmonary nocardiosis]: Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 1993 Jan;158(1):15-9. Unique Identifier : AIDSLINE MED/93144748; Wittenberg G; Schmidt-Rotte H; Schmidt M; Tschammler A; Krahe T; Institut fur Rontgendiagnostik, Universitat Wurzburg.; The radiological appearances and pulmonary changes during the acute stage and after recovery from pulmonary nocardiosis are described on the basis of 10 confirmed cases. Amongst the 10 patients there were 3 with malignant disease, 1 patient with AIDS, 3 patients following organ transplantation and 3 patients on steroi
Rapid purification of monomer HIV-2 Tat protein expressed in Escherichia coli.: Protein Expr Purif. 1993 Feb;4(1):24-31. Unique Identifier : AIDSLINE MED/93144955; Rhim H; Chan F; Echetebu CO; Rice AP; Division of Molecular Virology, Baylor College of Medicine,; Houston, Texas 77030.; Human immunodeficiency viruses types 1 and 2 encode transactivator proteins, named Tat-1 and Tat-2, that stimulate transcription directed by the viral long terminal repeat sequences. The Tat-1 and Tat-2 proteins are related in protein sequence and mechanism of transactivation. We expressed Tat proteins by in vitro tra
Cavitary aspergillosis as a complication of AIDS.: Can Assoc Radiol J. 1993 Feb;44(1):35-8. Unique Identifier : AIDSLINE MED/93145164; Morrison DL; Granton JT; Kesten S; Balter MS; Division of Respirology, Toronto Hospital, Ont.; The authors report the radiographic findings in two patients with the human immunodeficiency virus (HIV) who presented with cavitary lung disease caused by Aspergillus. Recognition of the disease in one of the patients led to successful medical therapy. Disease due to Aspergillus must be considered in HIV-positive pat
Primary pulmonary hypertension associated with HIV infection.: Can Assoc Radiol J. 1993 Feb;44(1):39-41. Unique Identifier : AIDSLINE MED/93145165; Duchesne N; Gagnon JA; Fouquette B; Couture G; Langis P; Bouchard G; Rioux M; Legare E; Universite Laval, Sainte-Foy, Que.; A Haitian woman with the human immunodeficiency virus (HIV) presented with dyspnea, cough, fatigue and lower abdominal pain of recent onset. Clinical, radiologic and hemodynamic investigations demonstrated pulmonary hypertension. The patient died a few days later. The pathological findings were compatible with primary
We must be willing to care for AIDS patients [letter; comment]: Crit Care Nurse. 1993 Feb;13(1):17. Unique Identifier : AIDSLINE MED/93145637; Delfin EP
Modeling the behavior and attributes of injecting drug users: a new approach to identifying HIV risk practices.: Int J Addict. 1993 Jan;28(2):129-52. Unique Identifier : AIDSLINE MED/93146737; Frischer M; Haw S; Bloor M; Goldberg D; Green S; McKeganey N; Covell R; Communicable Diseases (Scotland) Unit, Ruchill Hospital, Glasgow.; The behaviors and attributes of 503 Scottish injecting drug users were modeled using the linear structural equations program LISREL. Drug use was directly related to prison experience, sexual activity, sharing of injecting equipment, and prostitution. Although the prevalence of HIV among the sample was low (2.0%), the
Clinical and laboratory evaluation of AIDS trichopathy.: Int J Dermatol. 1993 Jan;32(1):33-8. Unique Identifier : AIDSLINE MED/93146761; Sadick NS; Department of Medicine, Cornell University Medical College, New; York, New York.; BACKGROUND. The present study reports the incidence of trichocutaneous disorders studied in 500 patients infected with HIV 1 in a large university-based setting. Correlation of these findings with immunologic function at the time of diagnosis is presented. Unusual presentations and therapeutic interventions are discus
Calciphylaxis in patients with human immunodeficiency virus infection and renal disease [letter; comment]: J Am Acad Dermatol. 1993 Jan;28(1):135-6. Unique Identifier : AIDSLINE MED/93147300; Bamberger N; Emmerich J; Fiessinger JN
Periodontal microflora of HIV positive subjects with gingivitis or adult periodontitis.: J Periodontol. 1993 Jan;64(1):48-56. Unique Identifier : AIDSLINE MED/93148071; Moore LV; Moore WE; Riley C; Brooks CN; Burmeister JA; Smibert RM; Department of Anaerobic Microbiology, Virginia Polytechnic; Institute and State University, Blacksburg.; The subgingival microflora of 39 HIV+ subjects with gingivitis or adult periodontitis was cultured quantitatively anaerobically for bacteria, spirochetes, and mycoplasma and aerobically for yeasts. Isolates were characterized by conventional biochemical tests, polyacrylamide gel electrophoresis of soluble proteins, ce
Epidemiological pattern of HIV infection in Australia.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S1-4. Unique Identifier : AIDSLINE MED/93148103; Kaldor J; National Centre in HIV Epidemiology and Clinical Research, St.; Vincent's Hospital Medical Centre, Sydney, Australia.; Human immunodeficiency virus (HIV) infection in Australia has been transmitted primarily through sex between men. Multiple sources of information, including backprojection from AIDS cases and longitudinal studies involving repeat testing for HIV antibody, indicate that the rate
Enteropathy in HIV infection.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S16-9. Unique Identifier : AIDSLINE MED/93148106; La Brooy JT; Department of Medicine, Royal Adelaide Hospital, South Australia.; Enteropathy occurs frequently in persons infected with human immunodeficiency virus (HIV), and symptoms related to the gut are a major cause of debility. The pathogens associated with disease are diverse, often difficult to detect, and frequently poorly responsive to any therapeutic intervention. This brief review exa
Pediatric HIV: Australian perspective.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S20-3. Unique Identifier : AIDSLINE MED/93148107; Ziegler JB; Palasanthiran P; Cruickshank M; Langdon P; Paediatric AIDS Unit, Prince of Wales Children's Hospital,; Randwick, Australia.; Pediatric infection with human immunodeficiency virus (HIV) in Australia , as elsewhere, now reflects HIV seroprevalence in women of childbearing age although numbers remain small. A perinatal transmission rate of approximately 30% has been observed. The rate appears to be higher
HIV antibody testing in Australia.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S24-8. Unique Identifier : AIDSLINE MED/93148108; Dax EM; Vandenbelt TA; National HIV Reference Laboratory, Fairfield Hospital, Victoria,; Australia.; Testing for antibody to human immunodeficiency virus (HIV) in Australia is subjected to continual monitoring for ensuring that the performance of tests in the field is reliable and provides accurate data on HIV tests and testing that are unique to Australia.
Clinical immunology and HIV infection.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S29-31. Unique Identifier : AIDSLINE MED/93148109; French MA; Department of Clinical Immunology, Royal Perth Hospital,; Australia.; Clinical immunologists play a major role in the multidisciplinary approach to the management of human immunodeficiency virus (HIV) infection and its complications in Australia , through involvement with the clinical and laboratory management of patients as well as with research o
Viral markers in HIV infection and AIDS.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S32-5. Unique Identifier : AIDSLINE MED/93148110; Cunningham AL; Dwyer DE; Dowton DN; Virology Department, ICPMR, Westmead Hospital, University of; Sydney, Australia.; Viral and immune markers are used for monitoring either progression of human immunodeficiency virus (HIV) disease or response to antiviral therapy. Ideal properties of viral markers are that they are present in all HIV-infected persons at all stages of disease, that they are related to disease pathogenesis, that they
New developments in the clinical use of didanosine.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S47-50. Unique Identifier : AIDSLINE MED/93148112; Kahn J; Department of Medicine, San Francisco General Hospital, CA 94110.; Didanosine (ddI) is a purine analogue that demonstrates in vitro anti-human immunodeficiency virus (HIV) activity, effects on the surrogate markers CD4+ T-lymphocytes and p24 antigen, and has adequate oral bio-availability. Recently, 500 mg/day of ddI in sachet form demonstrated clinical effectiveness compared with zi
HIV and malignancy.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S5-9. Unique Identifier : AIDSLINE MED/93148113; Boyle MJ; Sewell WA; Milliken ST; Cooper DA; Penny R; Centre for Immunology, University of New South Wales, Sydney,; Australia.; Although a number of tumors in patients infected with the human immunodeficiency virus have been reported, Kaposi s sarcoma and non-Hodgkin s lymphoma remain the two principal malignancies. This article provides an Australian perspective of the recent advances in research into mali
Prophylaxis of opportunistic infections in patients with HIV infection.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S56-60. Unique Identifier : AIDSLINE MED/93148115; Carr A; Penny R; Cooper DA; Centre for Immunology, St. Vincent's Hospital, Sydney, Australia.; Prophylaxis of opportunistic infections in patients with human immunodeficiency virus (HIV) infection has been one of the major factors responsible for increasing patient survival. Secondary prophylaxis of most opportunistic infections is warranted, although in most instances the optimal therapy remains to be determin
Immune modulation in HIV infection: fact or fantasy?: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S61-7. Unique Identifier : AIDSLINE MED/93148116; Benson EM; Department of Clinical Immunology, Westmead Hospital, Australia.; Since the recognition of AIDS a decade ago, many have postulated that immune modulators would provide the therapeutic intervention necessary for preventing disease progression and death. However, despite rapid advances in our understanding of disease pathogenesis and significant achievements in the area of antiviral d
Current status of clinical trials in HIV disease in Australia.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S68-71. Unique Identifier : AIDSLINE MED/93148117; Goldstein D; Cooper DA; National Centre in HIV Epidemiology and Clinical Research,; Sydney, Australia.; Clinical trials in Australia in diseases related to human immunodeficiency virus (HIV) have steadily expanded from the earliest national study of zidovudine to a range of trials either actively recruiting or being activated that cover a wide spectrum of primary viral, opportunis
Developing quality primary care services in HIV/AIDS care: the educational imperative.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S72-6. Unique Identifier : AIDSLINE MED/93148118; Irvine S; Penny R; Anns M; Centre for Immunology, St. Vincent's Hospital, Sydney, Australia.; In recognition of the growing demand for services related to infection with human immunodeficiency virus (HIV) in nonmetropolitan centers, the New South Wales Department of Health has developed a program for training selected medical practitioners from throughout the state in the management of HIV infection. This arti
The role of the primary care physician.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S77-83. Unique Identifier : AIDSLINE MED/93148119; McMurchie M; Increased emphasis on community-based care of people with human immunodeficiency virus (HIV) infection and AIDS is recommended by the National HIV/AIDS Strategy. Patients prefer to be treated within their community, and primary care reduces the demand on scarce, costly, and already overloaded hospital facilities. Thus
Posterior subcapsular cataracts associated with megestrol acetate therapy.: J Cataract Refract Surg. 1993 Jan;19(1):90-1. Unique Identifier : AIDSLINE MED/93148167; Aronson NE; Amegin GP; Infectious Disease Service, William Beaumont Army Medical Center,; El Paso, Texas.; Megestrol acetate, used for eight weeks as an appetite stimulant in a man infected with human immunodeficiency virus, was associated with the development of bilateral posterior subcapsular cataracts. We propose that the glucocorticoid properties of megestrol were contributory. Complicating this association, the patien
Symmetry-based inhibitors of HIV protease. Structure-activity studies of acylated 2,4-diamino-1,5-diphenyl-3-hydroxypentane and 2,5-diamino-1,6-diphenylhexane-3,4-diol.: J Med Chem. 1993 Feb 5;36(3):320-30. Unique Identifier : AIDSLINE MED/93148294; Kempf DJ; Codacovi L; Wang XC; Kohlbrenner WE; Wideburg NE; Saldivar A; Vasavanonda S; Marsh KC; Bryant P; Sham HL; et al; Pharmaceutical Products Division, Abbott Laboratories, Abbott; Park, Illinois 60064.; The structure-activity relationships in two series of novel, symmetry-based inhibitors of HIV protease, the enzyme responsible for maturation of the human immunodeficiency virus, are described. Beginning with lead compounds 3-6, the effect of adding polar, heterocyclic end groups to one or both ends of the symmetric o
Novel 6-alkoxypurine 2',3'-dideoxynucleosides as inhibitors of the cytopathic effect of the human immunodeficiency virus.: J Med Chem. 1993 Feb 5;36(3):378-84. Unique Identifier : AIDSLINE MED/93148300; Burns CL; St Clair MH; Frick LW; Spector T; Averett DR; English ML; Holmes TJ; Krenitsky TA; Koszalka GW; Division of Experimental Therapy, Burroughs Wellcome Co.,; Research Triangle Park, North Carolina 27709.; Twenty-one 6-alkoxypurine 2 ,3 -dideoxynucleosides were enzymatically synthesized with nucleoside phosphorylases purified from E. coli. Eighteen analogs exhibited anti-HIV-1 activity in MT4 cells. Two analogs, 6-(hexyloxy)-(17) and 6-(heptyloxy)-(18) purine 2 ,3 -dideoxynucleoside, were as potent as 2 ,3 -dideoxyinosi
HIV reporting in Tennessee: impact and trends.: J Tenn Med Assoc. 1993 Feb;86(2):64-5. Unique Identifier : AIDSLINE MED/93148636; Wood L; Tennessee Department of Health.
[Acute endocarditis due to Streptococcus pyogenes (letter)]: Med Clin (Barc). 1993 Jan 23;100(3):118. Unique Identifier : AIDSLINE MED/93148707; Morla J; Antela C; Masa L; Barrio E
[AIDS in the elderly patient (letter)]: Med Clin (Barc). 1993 Jan 23;100(3):118-9. Unique Identifier : AIDSLINE MED/93148708; Garcia F; Mallolas J; Miro JM; Gatell JM
Mycobacterium bovis infections in San Diego: a clinicoepidemiologic study of 73 patients and a historical review of a forgotten pathogen.: Medicine (Baltimore). 1993 Jan;72(1):11-37. Unique Identifier : AIDSLINE MED/93148846; Dankner WM; Waecker NJ; Essey MA; Moser K; Thompson M; Davis CE; Department of Pediatrics, University of California, San Diego,; California.; We have presented 73 patients (48 adults and 25 children) with microbiologically documented M. bovis infections identified over the 12-year period from 1980 through 1991. Epidemiologic investigation of these patients revealed that the majority (80%) were of Hispanic origin. The non-Hispanic patients either had travele
Microbiology laboratory clues to the diagnosis of HIV infection.: Med J Aust. 1993 Feb 15;158(4):255-60. Unique Identifier : AIDSLINE MED/93148904; Marriott D; Department of Microbiology, St Vincent's Hospital, Darlinghurst,; NSW.; Microbiological investigations can provide an early clue to the possibility of unsuspected underlying HIV infection. These case studies were randomly selected from the author s clinical practice and do not represent unusual or uncommon occurrences; they highlight the constant need to ask Could it be HIV? when interpre
Other laboratory clues to the diagnosis of HIV infection. A key summary.: Med J Aust. 1993 Feb 15;158(4):261. Unique Identifier : AIDSLINE MED/93148905; Garsia RJ; Department of Immunology, Royal Prince Alfred Hospital,; Camperdown, NSW.; The variety of problems induced by HIV means that any one of a wide range of investigations may uncover the first clue to unsuspected infection. Some of the more common abnormalities reported on by pathologists and radiologists which should raise the thought of underlying HIV infection are listed in this summary.
HIV infection in paediatric practice.: Med J Aust. 1993 Feb 15;158(4):262. Unique Identifier : AIDSLINE MED/93148906; Ziegler JB; Department of Immunology, Prince of Wales Children's Hospital,; Randwick, NSW.; Worldwide, most new HIV infections in children are transmitted from the mother before, during or after birth. This mode of transmission is likely to become more common in Australian paediatric practice, sometimes in circumstances where the mother s HIV status is unknown and unsuspected.
HIV infection in obstetric and gynaecological practice.: Med J Aust. 1993 Feb 15;158(4):263. Unique Identifier : AIDSLINE MED/93148907; Giles WB; Clezy K; Department of Obstetrics and Gynaecology, John Hunter Hospital,; New Lambton Heights, NSW.; The initial impact of HIV infection on the practising obstetrician and gynaecologist was specifically related to the treatment of HIV positive women who were pregnant. The current North American experience suggests that HIV will be an important consideration in gynaecology from now on.
HIV infection in surgical practice.: Med J Aust. 1993 Feb 15;158(4):264-5. Unique Identifier : AIDSLINE MED/93148908; Truskett PG; Department of Surgery, Prince of Wales Hospital, Randwick, NSW.; When HIV is mentioned in a surgical forum a debate will often follow about universal testing and barrier precautions. Unfortunately, there is little discussion of the many ways that HIV-infected patients may present primarily to the surgeon. Although lifestyle risk factors are important clues, unusual clinical feature
HIV infection in drug and alcohol practice [see comments]: Med J Aust. 1993 Feb 15;158(4):266. Unique Identifier : AIDSLINE MED/93148909; Wodak A; Drug and Alcohol Services, St Vincent's Hospital, Darlinghurst,; NSW.; The injecting of illicit drugs frequently involves the sharing of injection equipment and a risk of HIV transmission. Injecting drug use at any time since 1980 should be considered a high-risk activity and users should be advised to have HIV testing. Recognition of this important lifestyle clue is more likely to occur
A practitioner's guide to HIV testing.: Med J Aust. 1993 Feb 15;158(4):267-8. Unique Identifier : AIDSLINE MED/93148910; Carne PT; Ross M; Kemp RJ; Department of Infectious Diseases, Royal Brisbane Hospital,; Herston, QLD.; So far Could it be HIV? has examined many of the clues obtained from the clinical history and physical examination that might make an alert health care worker consider the diagnosis of HIV infection. Here we examine strategies for seeking permission for HIV testing and give advice on interpreting the results.
HIV, discrimination and health care students [letter]: Med J Aust. 1993 Feb 15;158(4):288-90. Unique Identifier : AIDSLINE MED/93148922; Stanek ST; Neilsen G; Plummer D; O'Connor C
Clinical problem-solving: treating before knowing [letter; comment]: N Engl J Med. 1993 Feb 25;328(8):582-3. Unique Identifier : AIDSLINE MED/93149230; Hirsch RL
More on disclosure of AIDS in celebrities [letter; comment]: N Engl J Med. 1993 Feb 25;328(8):583; discussion 584. Unique Identifier : AIDSLINE MED/93149232; Carrino AF; Bayer R
Montagnier and Mayor create AIDS foundation [news]: Nature. 1993 Jan 28;361(6410):287. Unique Identifier : AIDSLINE MED/93149256; Butler D
WHO vote upsets Western nations [news]: Nature. 1993 Jan 28;361(6410):290. Unique Identifier : AIDSLINE MED/93149258; Swinbanks D; Mervis J; Dickson D
HIV tropism [letter; comment]: Nature. 1993 Jan 28;361(6410):309-10. Unique Identifier : AIDSLINE MED/93149266; Moore J; Ho D
HIV tropism [letter; comment]: Nature. 1993 Jan 28;361(6410):310. Unique Identifier : AIDSLINE MED/93149267; Schuitemaker H; Groenink M; Tersmette M; Miedema F
AIDS cholangiopathy as the first sign of HIV infection.: N C Med J. 1993 Jan;54(1):16-7. Unique Identifier : AIDSLINE MED/93149281; Lee JG; Grech P; Edwards P; Wilson JA; Department of Medicine, Duke University Medical Center, Durham; 27710.
Psychosocial issues in pediatric AIDS.: N C Med J. 1993 Jan;54(1):18-23. Unique Identifier : AIDSLINE MED/93149282; Weedy C; Duke University Medical Center, Durham.
The road to hell. New rules to protect patients from being infected with HIV by their doctors [see comments]: N C Med J. 1993 Jan;54(1):6-7. Unique Identifier : AIDSLINE MED/93149289; Ellenbogen C; Fayetteville Area Health Education Center, Cape Fear Valley; Medical Center, 28304.
Tuberculosis in the AIDS era.: N C Med J. 1993 Jan;54(1):9-14. Unique Identifier : AIDSLINE MED/93149290; Ellenbogen C; Fayetteville Area Health Education Center, Cape Fear Valley; Medical Center, 28304.
[Increase in unsafe sex behavior among homosexual men in Amsterdam]: Ned Tijdschr Geneeskd. 1993 Jan 23;137(4):209-11. Unique Identifier : AIDSLINE MED/93149298; de Wit JB; van Griensven GJ; Sandfort TG; Coutinho RA; Rijksuniversiteit, Interfacultaire Werkgroep Homostudies,; Utrecht.; Since 1984 a decrease in the prevalence of unprotected anogenital intercourse among homosexual men was observed in a longitudinal cohort study in Amsterdam. Two years ago, there was a strong indication that this trend was reversed, as the number of cases of gonorrhoea among homo- and bisexual visitors of the municipal
Workplace stress rated for AIDS caregivers [news]: Occup Health Saf. 1993 Jan;62(1):12-4. Unique Identifier : AIDSLINE MED/93149538
Complications of dental surgery in persons with HIV disease.: Oral Surg Oral Med Oral Pathol. 1993 Feb;75(2):165-7. Unique Identifier : AIDSLINE MED/93149553; Porter SR; Scully C; Luker J; Centre for the Study of Oral Disease, University of Bristol; Dental Hospital and School, England.; Post tooth extraction infective complications have occasionally been described in HIV-infected persons. However, there is little objective data as to the frequency of this and the need for antibiotic prophylaxis. Similarly the frequency of postextraction bleeding in patients infected with HIV, who may have thrombocyto
Treatment of oral Kaposi's sarcoma with a sclerosing agent in AIDS patients. A preliminary study.: Oral Surg Oral Med Oral Pathol. 1993 Feb;75(2):192-8. Unique Identifier : AIDSLINE MED/93149559; Lucatorto FM; Sapp JP; Section of Diagnostic Sciences, School of Dentistry, University; of California, Los Angeles.; Presently oral Kaposi s sarcoma is primarily treated with systemic and intralesional chemotherapy, immunotherapy, radiation, and occasionally lasers. Each of these modalities achieves varying degrees of success. In patients with acquired immunodeficiency syndrome, the traditional treatments are frequently accompanied
AIDS survey shows need for more education.: Pa Med. 1993 Jan;96(1):28. Unique Identifier : AIDSLINE MED/93149624
Lack of effect of clinical research protocol participation on morbidity measures in human immunodeficiency virus-infected children.: Pediatr Infect Dis J. 1993 Feb;12(2):157-9. Unique Identifier : AIDSLINE MED/93149750; Gross ME; Smith EO; Kline MW; Department of Pediatrics, Baylor College of Medicine, Houston, TX; 77030.
Management of recalcitrant pain in a pediatric acquired immunodeficiency syndrome patient.: Pediatr Infect Dis J. 1993 Feb;12(2):159-60. Unique Identifier : AIDSLINE MED/93149751; Anand A; Carmosino L; Glatt AE; Department of Medicine, Nassau County Medical Center, East; Meadow, NY.
Sudden infant death among children born to women with human immunodeficiency virus type 1 infection [letter]: Pediatr Infect Dis J. 1993 Feb;12(2):172. Unique Identifier : AIDSLINE MED/93149762; Bulterys M; Lepage P; Hitimana DG; Dushimimana A; Van de Perre P; Saah A
To believe or not to believe.: Nurs Times. 1993 Jan 6-12;89(1):39. Unique Identifier : AIDSLINE MED/93149834; Griffiths P
Testing for HIV in saliva works well [news]: Nurs Times. 1993 Jan 6-12;89(1):9. Unique Identifier : AIDSLINE MED/93149843
HIV patients slam insensitive care [news]: Nurs Times. 1993 Jan 20-26;89(3):9. Unique Identifier : AIDSLINE MED/93149862
The associations between childhood asthma and atopy, and parental asthma, hay fever and smoking.: Paediatr Perinat Epidemiol. 1993 Jan;7(1):67-76. Unique Identifier : AIDSLINE MED/93149896; Jenkins MA; Hopper JL; Flander LB; Carlin JB; Giles GG; Faculty of Medicine, Epidemiology Unit, University of Melbourne,; Parkville, Victoria, Australia.; The aim of this analysis was to examine the degree to which a life time prevalence of asthma in a 7-year-old child is statistically associated with atopic conditions of the child, and with parental asthma, hay fever and smoking. In 1968, 8585 children who were born in 1961 and who were attending school in Tasmania wer
Incidence of suicidality in AIDS and HIV-positive patients attending a psychiatry outpatient program.: Psychosomatics. 1993 Jan-Feb;34(1):33-40. Unique Identifier : AIDSLINE MED/93150122; O'Dowd MA; Biderman DJ; McKegney FP; Department of Psychiatry, Montefiore Medical Center, Albert; Einstein College of Medicine, Bronx, New York 10467.; Current suicidality and many other characteristics were assessed in 183-patients in the various stages of HIV infection who were referred to a specialized HIV-related psychiatric clinic. Intravenous drug use was the most common HIV risk factor. Patients with AIDS had significantly less current suicidal ideation than p
Human immunodeficiency virus infection, exercise and athletics.: Sports Med. 1993 Jan;15(1):6-13. Unique Identifier : AIDSLINE MED/93150243; Calabrese LH; LaPerriere A; Section of Clinical Immunology, Cleveland Clinic Foundation,; Ohio.
[Latex allergy--an increasing problem in clinical practice]: Schweiz Med Wochenschr. 1993 Jan 30;123(4):113-9. Unique Identifier : AIDSLINE MED/93150275; Wyss M; Wuthrich B; Huwyler T; Elsner P; Allergiestation und Epikutantestlabor der Dermatologischen; Klinik, Universitatsspital Zurich.; In the last few years the allergenic potential of rubber has been receiving more and more attention. Its widespread application in medical devices and everyday objects has increased exposure to this allergen. The central role of rubber in the prevention of HIV infection has certainly played a part in this development.
The competing discourses of HIV/AIDS in sub-Saharan Africa: discourses of rights and empowerment vs discourses of control and exclusion.: Soc Sci Med. 1993 Feb;36(3):175-94. Unique Identifier : AIDSLINE MED/93150333; Seidel G; University of Bradford, West Yorkshire, U.K.; The competing discourses of HIV/AIDS circulating in sub-Saharan Africa are identified. These are medical, medico-moral, developmental (distinguishing between women in development and gender and development perspectives), legal, ethical, and the rights discourse of groups living with HIV/AIDS and of African pressure
Descriptive and normative ethics: class, context and confidentiality for mothers with HIV.: Soc Sci Med. 1993 Feb;36(3):195-202. Unique Identifier : AIDSLINE MED/93150334; Brown KH; Center for Health Policy and Ethics, Creighton University, Omaha,; NE 68178.; This descriptive analysis reports on how institutional imperatives and professional assessments define, constrain, and even override normative claims for confidentiality in health care for mothers with HIV/AIDS. The analysis draws upon interviews with seventy-two health, social work, administrative, research, and advo
Immune response of chimpanzees after immunization with the inactivated whole immunodeficiency virus (HIV-1), three different adjuvants and challenge.: Vaccine. 1993;11(1):67-74. Unique Identifier : AIDSLINE MED/93150676; Niedrig M; Gregersen JP; Fultz PN; Broker M; Mehdi S; Hilfenhaus J; Department of Microbiology, Behringwerke AG, Marburg, Germany.; Purified whole virus preparations of HIV-1 were produced from supernatants of infected cells and concentrated 5000-fold. After inactivation with formaldehyde, the concentrates were combined with one of three different adjuvants, and used to immunize three groups of three chimpanzees each. The chimpanzees were monitore
Renal lesions associated with human immunodeficiency virus infection: North American vs. European experience.: Adv Nephrol Necker Hosp. 1993;22:269-86. Unique Identifier : AIDSLINE MED/93151016; Nochy D; Glotz D; Dosquet P; Pruna A; Lemoine R; Guettier C; Weiss L; Hinglais N; Idatte JM; Mery JP; et al; Department of Nephrology, Hopital Broussais, Paris, France.
Efficacy of gadolinium in MR brain imaging of HIV-infected patients.: AJNR Am J Neuroradiol. 1993 Jan-Feb;14(1):257-63. Unique Identifier : AIDSLINE MED/93151070; Tuite M; Ketonen L; Kieburtz K; Handy B; Department of Radiology, University of Rochester Medical Center,; Strong Memorial Hospital, NY 14642.; PURPOSE: To determine the value of gadolinium in routine head MR imaging of HIV-infected patients. METHODS: One hundred and three consecutive human immunodeficiency virus-infected patients referred for head MR imaging were scanned without and with intravenous gadopentetate dimeglumine (Gd-DTPA) contrast. RESULTS: The
HIV-infected persons say health-care workers discriminate [news]: Am J Hosp Pharm. 1993 Jan;50(1):28, 32. Unique Identifier : AIDSLINE MED/93151260
Living positively with HIV [letter]: Am J Hosp Pharm. 1993 Jan;50(1):60, 62-3. Unique Identifier : AIDSLINE MED/93151265; Huffman MD
Male transvestite prostitutes and HIV risk.: Am J Public Health. 1993 Feb;83(2):260-2. Unique Identifier : AIDSLINE MED/93151323; Elifson KW; Boles J; Posey E; Sweat M; Darrow W; Elsea W; Department of Sociology, Georgia State University, Atlanta 30303.; Human immunodeficiency virus (HIV)-1, syphilis, and hepatitis B prevalence and associated risk factors were assessed among male transvestite prostitutes. Structured street-level interviews were conducted with 53 respondents in Atlanta, Ga, from July 1990 through July 1991. Test results from serum samples revealed that
Harnessing the energy of the mass media: HIV awareness in Dallas [news]: Am J Public Health. 1993 Feb;83(2):283-5. Unique Identifier : AIDSLINE MED/93151330; Krepcho M; Smerick M Jr; Freeman A; Alfaro A
A pilot study of HIV-infected immigrants [letter]: Am J Public Health. 1993 Feb;83(2):286. Unique Identifier : AIDSLINE MED/93151331; Loue S; Oppenheim S
The HIV rates of injection drug users in less-populated areas [letter; comment]: Am J Public Health. 1993 Feb;83(2):286-7. Unique Identifier : AIDSLINE MED/93151332; Steel E; Fleming PL; Needle R
Dexamethasone as adjuvant therapy for severe acute pharyngitis.: Ann Emerg Med. 1993 Feb;22(2):212-5. Unique Identifier : AIDSLINE MED/93151511; O'Brien JF; Meade JL; Falk JL; Department of Emergency Medicine, Orlando Regional Medical; Center, Florida.; STUDY OBJECTIVE: To determine the efficacy of dexamethasone as adjuvant therapy to improve pain relief in patients with severe, acute exudative pharyngitis. DESIGN: Prospective, randomized, double-blinded, placebo-controlled clinical trial. SETTING: Large, urban community hospital emergency department with an emergenc
Posttraumatic herpes zoster ophthalmicus as a presenting sign of human immunodeficiency virus infection.: Ann Ophthalmol. 1993 Jan;25(1):14-5. Unique Identifier : AIDSLINE MED/93151594; Netland PA; Zierhut M; Raizman MB; Department of Ophthalmology, Massachusetts Eye and Ear Infirmary,; Boston.; We present the case of a 38-year-old man who developed herpes zoster ophthalmicus after orbital blunt trauma. Additional evaluation revealed human immunodeficiency virus type 1 (HIV-1) infection. This case shows that varicella-zoster may be activated by local trauma and that herpes zoster ophthalmicus in young patient
Hypertrophic osteoarthropathy and AIDS [letter]: Ann Rheum Dis. 1993 Jan;52(1):82-3. Unique Identifier : AIDSLINE MED/93151675; Gil-Garcia L; Martin-Santos JM; Blanco-Cabero M; Tapias del Pozo JA; Martinez-Barrero F
HIV-infected health care professionals. Public opinion about testing, disclosing, and switching.: Arch Intern Med. 1993 Feb 8;153(3):313-20. Unique Identifier : AIDSLINE MED/93151688; Gerbert B; Bleecker T; Berlin M; Coates TJ; School of Dentistry, University of California, San Francisco.; BACKGROUND: We wanted to know what the public believes about the risks of human immunodeficiency virus (HIV) transmission in health care settings, and what opinions the public holds regarding HIV-infected health care professionals. We also wanted to uncover the correlates and predictors of those opinions. METHODS: A t
Clarithromycin and other antimicrobial agents in the treatment of disseminated Mycobacterium avium infections in patients with acquired immunodeficiency syndrome.: Arch Intern Med. 1993 Feb 8;153(3):368-72. Unique Identifier : AIDSLINE MED/93151693; Dautzenberg B; Saint Marc T; Meyohas MC; Eliaszewitch M; Haniez F; Rogues AM; De Wit S; Cotte L; Chauvin JP; Grosset J; Pulmonary Department, Groupe Hospitalier, Pitie-Salpetriere,; Paris, France.; BACKGROUND: Disseminated infection with Mycobacterium avium is common with late-stage acquired immunodeficiency syndrome (AIDS), and no antimicrobial agent has been found to be clearly effective. METHODS: A multicenter open trial was conducted to assess the antimicrobial activity and clinical efficacy of clarithromyci
Pneumocystis carinii thyroiditis. Report of three cases and review of the literature [published erratum appears in Arch Intern Med 1993 Apr 26;153(8):1002]: Arch Intern Med. 1993 Feb 8;153(3):393-6. Unique Identifier : AIDSLINE MED/93151697; Guttler R; Singer PA; Axline SG; Greaves TS; McGill JJ; Division of Endocrinology, University of Southern California; School of Medicine, Los Angeles.; Pneumocystis carinii infection of the thyroid gland has previously been described in only four living patients with acquired immunodeficiency syndrome, three of whom had been receiving inhaled pentamidine prophylaxis against P carinii pneumonia. We treated three additional patients with P carinii thyroid involvement,
Admission serum albumin and prognosis in acquired immunodeficiency syndrome [letter; comment]: Arch Intern Med. 1993 Feb 8;153(3):400. Unique Identifier : AIDSLINE MED/93151699; Boone MC; Sue DY
Human immunodeficiency virus-associated autonomic neuropathy, drug addiction, and zidovudine treatment [letter; comment]: Arch Intern Med. 1993 Feb 8;153(3):400-1. Unique Identifier : AIDSLINE MED/93151700; Confalonieri F; Villa A
N-linked oligosaccharides of simian immunodeficiency virus envelope glycoproteins are dispensable for the interaction with the CD4 receptor.: Biochem Biophys Res Commun. 1993 Jan 29;190(2):311-9. Unique Identifier : AIDSLINE MED/93151808; Benjouad A; Babas T; Montagnier L; Bahraoui E; Centre National de la Recherche Scientifique URA 1455, Faculte; de Medecine Nord, Marseille, France.; In contrast to others groups, we have previously shown that N-linked glycans of HIV-1 and HIV-2 envelope glycoproteins do not play a major role in the gp-CD4 interaction. In order to clarify these inconsistencies, we investigated the role of N-glycans in the interaction of SIV with the CD4 receptor. The inhibition of
OSHA's final bloodborne pathogens standard: Part II.: AAOHN J. 1993 Jan;41(1):8-15. Unique Identifier : AIDSLINE MED/93151918; Barlow R; Handelman E; The Bloodborne Pathogens Standard has specific requirements for employee hazard communication and training as well as management of regulated waste, contaminated laundry, and housekeeping procedures. OSHA recognizes the benefits of prophylactic use of hepatitis B vaccine and requires that it be made available, at no c
Qualitative changes in the human T-cell leukemia/lymphotropic virus type I env gene sequence in the spastic versus nonspastic tropical paraparesis are not correlated with disease specificity.: AIDS Res Hum Retroviruses. 1993 Jan;9(1):1-5. Unique Identifier : AIDSLINE MED/93152281; Boeri E; Gessain A; Garin B; Kazadi K; de The G; Franchini G; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, MD 20892.
Studies on the specificity of the vaccine effect elicited by inactivated simian immunodeficiency virus.: AIDS Res Hum Retroviruses. 1993 Jan;9(1):13-22. Unique Identifier : AIDSLINE MED/93152282; Cranage MP; Polyanskaya N; McBride B; Cook N; Ashworth LA; Dennis M; Baskerville A; Greenaway PJ; Corcoran T; Kitchin P; et al; Division of Pathology, PHLS Centre for Applied Microbiology &; Research, Salisbury, UK.; Inactivated, partially purified simian immunodeficiency virus (SIVmac) protected macaques from intravenous challenge with homologous and heterologous strains of SIV that had been grown on human cells but no protection against challenge with monkey peripheral blood mononuclear cell-grown SIVmac was afforded. Human immu
Human immunodeficiency virus type I provirus is demonstrated in peripheral blood monocytes in vivo: a study utilizing an in situ polymerase chain reaction.: AIDS Res Hum Retroviruses. 1993 Jan;9(1):69-76. Unique Identifier : AIDSLINE MED/93152288; Bagasra O; Pomerantz RJ; Department of Medicine, Jefferson Medical College, Thomas; Jefferson University, Philadelphia, PA 19107.; Human immunodeficiency virus type 1 (HIV-1) infects a variety of cell types in vivo. Monocyte/macrophages may be the major reservoir for HIV-1 in the solid tissues of HIV-1-infected individuals. Conflicting data have been reported, though, regarding the presence of HIV-1 provirus in peripheral blood monocytes isolated
Human immunodeficiency virus type 1 RNA detection in peripheral blood mononuclear cells by polymerase chain reaction: enhanced sensitivity after mitogenic stimulation [published erratum appears in AIDS Res Hum Retroviruses 1993 Mar;9(3):291]: AIDS Res Hum Retroviruses. 1993 Jan;9(1):77-82. Unique Identifier : AIDSLINE MED/93152290; Tetali SK; Oyaizu N; Paul M; Pahwa S; Department of Pediatrics, North Shore University Hospital-Cornell; University Medical College, Manhasset, NY 11030.; The aim of this study was to investigate whether stimulus-induced up-regulation of human immunodeficiency virus type 1 (HIV-1) expression in peripheral blood mononuclear cells (PBMC) could enhance the diagnostic sensitivity of the polymerase chain reaction (PCR). PBMC derived from 11 HIV-1-infected asymptomatic adults
Inhibition of human immunodeficiency virus type 1 replication by hydroxychloroquine in T cells and monocytes.: AIDS Res Hum Retroviruses. 1993 Jan;9(1):91-8. Unique Identifier : AIDSLINE MED/93152292; Sperber K; Kalb TH; Stecher VJ; Banerjee R; Mayer L; Division of Clinical Immunology, Mount Sinai Medical Center, New; York, NY 10029.; Chloroquine and its analogue hydroxychloroquine (HCQ) have been shown to inhibit a variety of viral infections including influenza and adenovirus through blockade of viral entry via inhibition of endosomal acidification. We have extended these observations to human immunodeficiency virus type 1 (HIV-1) infection utili
The epidemic of human immunodeficiency virus infection in Romanian children.: AIDS Res Hum Retroviruses. 1993 Jan;9(1):99-104. Unique Identifier : AIDSLINE MED/93152293; Patrascu IV; Dumitrescu O; Romania AIDS Association and Virology Laboratory, Bucharest.; Between June 1989 and May 1991, 29,020 subjects were tested for anti-human immunodeficiency virus (HIV) antibodies; 1079 were seropositive. A big discrepancy existed between the high seroprevalence in the group 0-3 yr of age, 11.22%, and that of 0.43% in the adult population. Moreover, only a small percentage of the p
Current classifications of HIV-associated periodontal diseases [see comments]: Br Dent J. 1993 Feb 6;174(3):102-5. Unique Identifier : AIDSLINE MED/93152322; Smith GL; Felix DH; Wray D; Department of Oral Medicine & Oral Pathology, University of; Edinburgh.; The occurrence of unusual and severe forms of periodontal disease in HIV-infected individuals is well recognised. Several classification schemes have been proposed in an effort to associate periodontal deterioration with progressive stages of HIV infection and to determine aetiological factors in tissue destruction. N
Nurses praised for 'major contribution' to AIDS care [news]: Nurs Stand. 1993 Dec 16-Jan 5;7(13-14):12. Unique Identifier : AIDSLINE MED/93152437
Cheaper, more accurate TB test is in the pipeline [news]: Nurs Stand. 1993 Dec 16-Jan 5;7(13-14):14. Unique Identifier : AIDSLINE MED/93152438
Immunoglobulins offer hope in AIDS survival [news]: Nurs Stand. 1993 Dec 16-Jan 5;7(13-14):15. Unique Identifier : AIDSLINE MED/93152439
Romania: something to celebrate [interview by Norah Casey]: Nurs Stand. 1993 Dec 16-Jan 5;7(13-14):16-7. Unique Identifier : AIDSLINE MED/93152440; Finlayson K
Whatever happened to HIV dementia? [editorial]: Int J STD AIDS. 1993 Jan-Feb;4(1):1-4. Unique Identifier : AIDSLINE MED/93152630; Catalan J; Thornton S
Factors associated with trichomoniasis, candidiasis and bacterial vaginosis.: Int J STD AIDS. 1993 Jan-Feb;4(1):21-5. Unique Identifier : AIDSLINE MED/93152632; Hart G; STD Control Branch, South Australia.; Of 6125 women attending an STD clinic from 1988 to 1991, 5365 (88%) were tested for vaginitis of whom 97 (1.8%) had trichomoniasis, 945 (17.6%) had candidiasis, 734 (13.7%) had bacterial vaginosis and 3628 (67.6%) were free of vaginal infection. Dual infections occurred in 49 (0.9%) patients. Independent predictors fo
Partner notification for human immunodeficiency virus infection in Colorado: results across index case groups and costs.: Int J STD AIDS. 1993 Jan-Feb;4(1):26-32. Unique Identifier : AIDSLINE MED/93152633; Spencer NE; Hoffman RE; Raevsky CA; Wolf FC; Vernon TM; Colorado Department of Health, STD/AIDS Section, Denver 80222.; To evaluate human immunodeficiency virus (HIV) partner notification and referral across index case groups, we analysed results of services provided by the Colorado Department of Health during 1988. Services were offered to 231 index cases; 226 (98%) accepted; 124 (65%) with unsafe behaviours identified 239 partners; 7
Antibiotic susceptibility, serovars and auxotypes of gonococcal isolates in Stockholm. Relation to geographical origin of the infection.: Int J STD AIDS. 1993 Jan-Feb;4(1):33-40. Unique Identifier : AIDSLINE MED/93152634; Bygdeman SM; Ruden AK; Jonsson A; Lidbrink P; Olofsson MB; Backman M; Gastrin B; Kallings I; Ramberg M; Rylander M; et al; Department of Clinical Bacteriology, Huddinge Hospital,; Stockholm, Sweden.; The antibiotic susceptibility, serovars and auxotypes were investigated in gonococcal strains isolated from all patients with gonorrhoea during one year in Stockholm, Sweden . The results were correlated to geographical origin of the infection. A total of 394 gonococcal strains were
Management of cervical intraepithelial neoplasia in departments of genitourinary medicine--a national survey.: Int J STD AIDS. 1993 Jan-Feb;4(1):41-2. Unique Identifier : AIDSLINE MED/93152635; Markos AR; Wade AA; Walzman M; Department of Genitourinary Medicine, Coventry & Warwickshire; Hospital, UK.; A national survey of the methods used in the diagnosis and treatment of cervical intraepithelial neoplasia (CIN) in the departments of genitourinary medicine (GUM) in the United Kingdom had been conducted through a postal questionnaire. The findings indicate that at present of 157 resp
Detection of IgG, IgM and IgA antibodies in patients with uncomplicated Chlamydia trachomatis infection: a comparison between enzyme linked immunofluorescent assay and isolation in cell culture.: Int J STD AIDS. 1993 Jan-Feb;4(1):43-8. Unique Identifier : AIDSLINE MED/93152636; Theunissen JJ; van Heijst BY; Chin-A-Lien RA; Wagenvoort JH; Stolz E; Michel MF; Department of Dermato-Venereology, Erasmus University, Rotterdam,; The Netherlands.; The diagnostic value of serum IgG, IgM and IgA in patients with uncomplicated urogenital Chlamydia trachomatis infection was compared with isolation in cell culture. C. trachomatis specific antibodies were determined with an enzyme linked immunofluorescent assay using elementary bodies from C. trachomatis serotypes E,
Beta-2 microglobulin as a marker of HIV disease status in Nairobi, Kenya.: Int J STD AIDS. 1993 Jan-Feb;4(1):49-51. Unique Identifier : AIDSLINE MED/93152637; Garden GA; Moss GB; Emonyi W; Bwayo J; Velentgas P; Kreiss J; Department of Physiology and Biophysics, University of; Washington, Seattle 98195.; Serum beta-2 microglobulin (beta 2-M) has prognostic value similar to lymphocyte profiles for predicting disease progression in those infected with the human immunodeficiency virus (HIV). However, the relationship between beta 2-M and HIV disease progression among inhabitants of countries with endemic tropical disease
The value of tests of cure following cervical chlamydial infection.: Int J STD AIDS. 1993 Jan-Feb;4(1):5-7. Unique Identifier : AIDSLINE MED/93152638; White DJ; Mann CH; Matthews RS; Leeming JG; Clay JC; Department of Genitourinary Medicine, General Hospital,; Birmingham, UK.; Test of cure (TOC) was performed 2, 4 and 6 weeks after treatment for cervical chlamydia infection with 10-14 days of Deteclo one tablet twice daily, erythromycin 500 mg twice daily or doxycycline 100 mg twice daily. Testing was by chlamydia culture and IDEIA (DAKO diagnostics Ltd). Discrepant results were subsequentl
Vulval Crohn's disease mimicking genital herpes [see comments]: Int J STD AIDS. 1993 Jan-Feb;4(1):54-6. Unique Identifier : AIDSLINE MED/93152640; Shen RN; Cybulska BA; Thin RN; McKee PH; Department of Genitourinary Medicine, St Thomas's Hospital,; London, UK.
STD in travellers presenting to a GUM clinic [letter]: Int J STD AIDS. 1993 Jan-Feb;4(1):59-60. Unique Identifier : AIDSLINE MED/93152641; Lister P; Robinson A
Do we need vulvar clinics in genitourinary medicine departments? [letter]: Int J STD AIDS. 1993 Jan-Feb;4(1):60-1. Unique Identifier : AIDSLINE MED/93152642; Morrison GD
Current smoking habits and genital infections in women [letter; comment]: Int J STD AIDS. 1993 Jan-Feb;4(1):61. Unique Identifier : AIDSLINE MED/93152643; Bignall JC
Herpes simplex virus infection in pregnancy and its management [letter; comment]: Int J STD AIDS. 1993 Jan-Feb;4(1):61. Unique Identifier : AIDSLINE MED/93152644; Woolley PD
Anogenital non-gonococcal neisseriae: prevalence and clinical significance.: Int J STD AIDS. 1993 Jan-Feb;4(1):8-12. Unique Identifier : AIDSLINE MED/93152645; McKenna JG; Fallon RJ; Moyes A; Young H; Genitourinary Medicine Unit, Royal Infirmary of Edinburgh, UK.; Over a 13-year period non-gonococcal neisseriae (NGN) were isolated from 114 of 88,670 patients (0.13%) screened for anogenital gonorrhoea at a Genitourinary Medicine Unit. During the same period there were approximately 9000 anogenital gonococcal infections (10%). The prevalence of NGN was 0.09% (27/31,500) in women,
[The future leading role of primary care in HIV/AIDS (letter)]: Aten Primaria. 1993 Jan;11(1):52. Unique Identifier : AIDSLINE MED/93152718; Gonzalez Lopez E
Human immunodeficiency virus-related conditions in children and adults with hemophilia: rates, relationship to CD4 counts, and predictive value.: Blood. 1993 Feb 1;81(3):828-34. Unique Identifier : AIDSLINE MED/93152857; Eyster ME; Rabkin CS; Hilgartner MW; Aledort LM; Ragni MV; Sprandio J; White GC; Eichinger S; de Moerloose P; Andes WA; et al; Department of Medicine, Pennsylvania State University School of; Medicine, Hershey.; To further elucidate the natural history of human immunodeficiency virus (HIV) infection, we studied intermediate HIV-related conditions occurring before acquired immunodeficiency syndrome (AIDS) in a prospectively observed multicenter cohort of 738 HIV-infected persons with hemophilia. We analyzed the frequency in ad
Human immunodeficiency virus detection and differential leukocyte counts are accurate and safer with formaldehyde-fixed blood [letter]: Blood. 1993 Feb 1;81(3):864-5. Unique Identifier : AIDSLINE MED/93152863; Kiessling AA; Crowell RC; Brettler D; Forsberg A; Wolf B
Cell-type-specific transactivation of the parathyroid hormone-related protein gene promoter by the human T-cell leukemia virus type I (HTLV-I) tax and HTLV-II tax proteins.: Blood. 1993 Feb 15;81(4):1017-24. Unique Identifier : AIDSLINE MED/93152870; Ejima E; Rosenblatt JD; Massari M; Quan E; Stephens D; Rosen CA; Prager D; Department of Medicine, Cedars-Sinai Medical Center, Los Angeles,; CA 90048.; The human T-cell leukemia virus type I (HTLV-I) and HTLV-II Tax proteins are potent transactivators of viral and cellular gene expression. Using deletion mutants, the downstream parathyroid hormone-related protein (PTHrP) promoter is shown to be responsive to both HTLV-I and HTLV-II Tax as well as the AP1/c-jun proto-
Detection of hepatitis B virus in plasma using flow cytometric analyses of polymerase chain reaction-amplified DNA incorporating digoxigenin-11-dUTP.: Blood. 1993 Feb 15;81(4):1083-8. Unique Identifier : AIDSLINE MED/93152879; Yang G; Ulrich PP; Aiyer RA; Rawal BD; Vyas GN; Department of Laboratory Medicine, University of California,; School of Medicine, San Francisco 94143-0134.; Blood donations are routinely screened by multiple serologic assays for antigens/antibodies associated with infection by blood-borne viruses, including hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency viruses (HIV-1 and HIV-2), and human T-cell lymphotropic virus (HTLV-I and HTLV-II). A direct
Interleukin-10 and acquired immunodeficiency syndrome lymphomas [letter; comment]: Blood. 1993 Feb 15;81(4):1106-7. Unique Identifier : AIDSLINE MED/93152883; Emilie D; Galanaud P; Raphael M; Joab I
Neuropsychological performance, mood, and complaints of cognitive and motor difficulties in individuals infected with the human immunodeficiency virus.: J Neuropsychiatry Clin Neurosci. 1993 Winter;5(1):86-93. Unique Identifier : AIDSLINE MED/93153185; Mapou RL; Law WA; Martin A; Kampen D; Salazar AM; Rundell JR; Henry M. Jackson Foundation for the Advancement of Military; Medicine, Military Medical Consortium for Applied Retroviral; Research, Rockville, Maryland 20850.; Seventy-nine military medical beneficiaries infected with human immunodeficiency virus (HIV+) and 27 HIV-seronegative control subjects (HIV-) completed a neuropsychological evaluation and a semistructured interview inquiring about difficulties in function. More HIV+ than HIV- subjects reported difficulties. HIV+ subje
Defective IL-6 secretion in HIV-infected haemophilia patients.: Clin Exp Immunol. 1993 Feb;91(2):249-56. Unique Identifier : AIDSLINE MED/93153901; Weimer R; Zipperle S; Daniel V; Zimmermann R; Opelz G; Institute of Immunology, University of Heidelberg, Germany.; To study the role of IL-6 in HIV-induced B cell defects, in vitro B cell responses and IL-6 secretion were determined simultaneously in 67 haemophilia patients. Twenty-three patients were HIV- (Group 1), 27 HIV+ stage CDC II, III (Group 2), and 17 were HIV+ stage CDC IV (Group 3). Pokeweed mitogen (PWM) was used for T
Differential cytokine gene expression and secretion after phagocytosis by a human monocytic cell line of Toxoplasma gondii compared with Mycobacterium tuberculosis.: Clin Exp Immunol. 1993 Feb;91(2):282-6. Unique Identifier : AIDSLINE MED/93153906; Friedland JS; Shattock RJ; Johnson JD; Remick DG; Holliman RE; Griffin GE; Division of Communicable Diseases, St. George's Hospital Medical; School, London, UK.; Toxoplasma gondii infection may be clinically silent in immunocompetent individuals but may cause fatal disease in immunocompromised patients such as those with HIV infection. Proinflammatory cytokines are known to be important in murine resistance to T. gondii but there are no data from human models of infection. We
Abnormal urinary protein excretion in HIV-infected patients [see comments]: Clin Nephrol. 1993 Jan;39(1):17-21. Unique Identifier : AIDSLINE MED/93153917; Kimmel PL; Umana WO; Bosch JP; Department of Medicine, George Washington University Medical; Center, Washington, D.C. 20037.; HIV infection has been associated with a variety of renal diseases, although the pathogenesis of such dysfunction is unknown. To determine whether HIV-infection is associated with glomerular permeability defects, and if so, the prevalence of the finding, we studied patients with various stages of HIV infection. Urine
Ultrasound findings in hepatic mycobacterial infections in patients with acquired immune deficiency syndrome (AIDS).: Clin Radiol. 1993 Jan;47(1):36-8. Unique Identifier : AIDSLINE MED/93153944; Wetton CW; McCarty M; Tomlinson D; Rosbotham J; Crofton ME; Department of Radiology, St Mary's Hospital, London.; Ultrasound findings in 12 AIDS patients with abdominal mycobacterial infections were reviewed and correlated with liver histology. Liver ultrasound abnormalities were common--present in 4/5 patients with Mycobacterium avium-intracellulare (MAI) and 7/7 patients with Mycobacterium tuberculosis (MTB) infection. The comm
Opportunistic pneumonia.: Curr Probl Diagn Radiol. 1993 Jan-Feb;22(1):3-35. Unique Identifier : AIDSLINE MED/93154127; Conces DJ Jr; Department of Radiology, Indiana University School of Medicine,; Indianapolis.; Patients with abnormalities in their immune defense mechanisms are frequently encountered in the practice of medicine. These patients have increased susceptibility to infections that often involve the lung. Many of these infections are caused by opportunistic organisms that typically do not produce disease in individu
Recovery of infectious HIV following the passage of apoptotic cellular debris through phagocytic macrophages.: Chest. 1993 Feb;103(2 Suppl):102S-103S. Unique Identifier : AIDSLINE MED/93154149; Kornbluth RS; Rhodes J; Richman DD; Department of Medicine, University of California, San Diego.
HIV infection of the lung. Role of virus-infected macrophages in the pathophysiology of pulmonary disease.: Chest. 1993 Feb;103(2 Suppl):103S-108S. Unique Identifier : AIDSLINE MED/93154150; Meltzer MS; Kornbluth RS; Hansen B; Dhawan S; Gendelman HE; Department of Cellular Immunology, Walter Reed Army Institute of; Research, Washington.
Alveolar macrophages in HIV-1 infection express accessory molecules, activation markers, and release increased biological response modifiers.: Chest. 1993 Feb;103(2 Suppl):108S-111S. Unique Identifier : AIDSLINE MED/93154151; Agostini C; Trentin L; Zambello R; Bulian P; Garbisa S; Cipriani A; Cadrobbi P; Semenzato G; Padua University School of Medicine, Department of Clinical; Medicine, Italy.
HIV impairs alveolar macrophage mannose receptor function against Pneumocystis carinii.: Chest. 1993 Feb;103(2 Suppl):111S-112S. Unique Identifier : AIDSLINE MED/93154152; Koziel H; Kruskal BA; Ezekowitz RA; Rose RM; New England Deaconess Hospital, Boston.
Interaction between a membrane-associated serine proteinase of U-937 monocytes and peptides from the V3 loop of the human immunodeficiency virus type 1 (HIV-1) gp120 envelope glycoprotein.: FEBS Lett. 1993 Feb 8;317(1-2):167-72. Unique Identifier : AIDSLINE MED/93154511; Avril LE; Di Martino-Ferrer M; Barin F; Gauthier F; Laboratoire d'Enzymologie et Chimie des Proteines, Universite; Francois Rabelais, Tours, France.; A trypsin-like proteinase which is inhibited by recombinant gp120 and by synthetic peptides of various lengths spanning the conserved sequence of the V3 loop has been purified and partially characterized from a U-937 cell membrane extract. V3 loop peptides behave as competitive inhibitors of the enzyme, while gp120 ex
The self-sustained sequence replication amplification system--move over, PCR.: Hepatology. 1993 Feb;17(2):344-6. Unique Identifier : AIDSLINE MED/93154687; Lown KS; Division of Gastroenterology, University of Michigan Medical; Center, Ann Arbor 48109.
Perceived vulnerability to HIV/AIDS in the US and Zimbabwe.: Int Nurs Rev. 1993 Jan-Feb;40(1):13-6, 24. Unique Identifier : AIDSLINE MED/93154864; Munodawafa D; Bower DA; Webb AA; University of Akron, Ohio.; The majority of nurses in the US and Zimbabwe feel they have sufficient knowledge to protect themselves from acquiring AIDS, according to a study conducted by the authors, leading them to recommend that nursing students be allowed to openly discuss their feelings about vulnerabil
Breaking the silence: the need for counselling of HIV/AIDS patients.: Int Nurs Rev. 1993 Jan-Feb;40(1):17-20, 24. Unique Identifier : AIDSLINE MED/93154865; Nkowane AM; Webster University in Geneva, Switzerland.; The care and management of persons with HIV infection and AIDS pose tremendous challenges to families, as individuals with the disease will more likely be taken care of within their homes when discharged from hospital. For effective care to be provided, relatives and families must be able to provide emotional, psychol
AIDS: a community challenge [news]: Int Nurs Rev. 1993 Jan-Feb;40(1):9. Unique Identifier : AIDSLINE MED/93154870
Racial minorities at increased risk an Arkansas HIV/AIDS report: autumn 1992.: J Ark Med Soc. 1993 Jan;89(8):390-3. Unique Identifier : AIDSLINE MED/93154959; The demographics of the HIV epidemic continue to change. Rates among white homosexuals seem to be leveling off; but there does not appear to be a corresponding decline among black homosexuals. Additionally, having found its first foothold among heterosexual injection drug users, increases in reported infection can be
Pharmaceutical research companies testing 92 AIDS medicines [news]: J Ark Med Soc. 1993 Jan;89(8):411. Unique Identifier : AIDSLINE MED/93154961
Detection of tumor necrosis factor-alpha-positive cells in cerebrospinal fluid of patients with HTLV-I-associated myelopathy.: J Neuroimmunol. 1993 Feb;42(2):127-30. Unique Identifier : AIDSLINE MED/93155318; Nakamura S; Nagano I; Yoshioka M; Shimazaki S; Onodera J; Kogure K; Department of Neurology, Institute of Brain Diseases, Tohoku; University School of Medicine, Sendai, Japan.; Tumor necrosis factor (TNF)-alpha-positive cells constituted 1.6-18% and 8.2-23.5% of the total number of cerebrospinal fluid cells from six of 12 patients with HTLV-I-associated myelopathy and in all samples obtained from inflammatory cases, respectively. However, in non-inflammatory cases no TNF-alpha-positive cells
Fluctuation of HTLV-I proviral DNA in peripheral blood mononuclear cells of HTLV-I-associated myelopathy.: J Neuroimmunol. 1993 Feb;42(2):147-54. Unique Identifier : AIDSLINE MED/93155321; Kubota R; Fujiyoshi T; Izumo S; Yashiki S; Maruyama I; Osame M; Sonoda S; Third Department of Medicine, Kagoshima University, Japan.; To assess the immunopathological significance of the increased replication of human T-cell leukemia virus type I (HTLV-I) in HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) we investigated the dynamics of HTLV-I proviral DNA in peripheral blood mononuclear cells (PBMC) of HAM/TSP patients at differ
Anti-lymphocyte antibodies and circulating immune complexes in the sera of patients with myelopathy associated with human T lymphotropic virus type-I.: J Neuroimmunol. 1993 Feb;42(2):161-6. Unique Identifier : AIDSLINE MED/93155323; Shimada K; Koh CS; Yanagisawa N; Tsukada N; Osame M; Department of Medicine (Neurology), Shinshu University School of; Medicine, Matsumoto, Japan.; We measured levels of circulating immune complexes in the human T-lymphotropic virus type I (HTLV-I)-associated myelopathy (HAM) by Raji cell assay and C1q binding assay using an enzyme-linked immunosorbent assay (ELISA). The levels of anti-lymphocyte antibody were also measured using normal donor peripheral blood T-l
Stress-induced modulation of the primary cellular immune response to herpes simplex virus infection is mediated by both adrenal-dependent and independent mechanisms.: J Neuroimmunol. 1993 Feb;42(2):167-76. Unique Identifier : AIDSLINE MED/93155324; Bonneau RH; Sheridan JF; Feng N; Glaser R; Department of Medical Microbiology and Immunology, Ohio State; University College of Medicine, Columbus 43210.; A murine model of herpes simplex virus (HSV) infection was used to examine the role of the adrenal gland in restraint stress-induced suppression of viral immunity. Adrenal-dependent mechanisms were important for suppressing the generation of HSV-specific cytotoxic T lymphocytes (CTL) but not the associated diminished
Cerebrospinal fluid interferon-gamma is increased in HTLV-I-associated myelopathy.: J Neuroimmunol. 1993 Feb;42(2):223-6. Unique Identifier : AIDSLINE MED/93155331; Kuroda Y; Matsui M; Section of Neurology, Department of Internal Medicine, Saga; Medical School, Japan.; Serum and cerebrospinal fluid (CSF) levels of interferon-gamma (IFN-gamma) were assayed with an immunoenzymetric method in 16 patients with HTLV-I-associated myelopathy (HAM). IFN-gamma levels were elevated in serum of two patients and in CSF of nine. Although there was no significant association between the clinical
Evaluation of services for people with HIV/AIDS in an inner-city health authority: perspectives of key service providers.: J Adv Nurs. 1993 Jan;18(1):69-79. Unique Identifier : AIDSLINE MED/93155410; Beedham HM; Wilson-Barnett J; Department of Nursing Studies, King's College, University of; London, England.; This paper reports the findings of the first phase of a study designed to assess the needs of people with HIV and AIDS and the extent to which these needs are being met by services in Camberwell Health Authority in inner London. The study involves collecting information and opinions from key service providers, clients
AIDS-related experience, knowledge, attitudes and beliefs amongst nurses in an area with a high rate of HIV infection.: J Adv Nurs. 1993 Jan;18(1):80-8. Unique Identifier : AIDSLINE MED/93155412; Plant ML; Foster J; Department of Psychiatry, University of Edinburgh, Scotland.; The results are presented of a survey of the AIDS-related knowledge, attitudes and beliefs of a random sample of 600 qualified nurses in the Lothian Region of Scotland. This locality is characterized by a high rate of detected HIV infection which is mainly associated with intravenous drug use. This study indicated tha
Polymerase chain reaction in situ: intracellular amplification and detection of HIV-1 proviral DNA and other specific genes.: J Immunol Methods. 1993 Jan 14;158(1):131-45. Unique Identifier : AIDSLINE MED/93155486; Bagasra O; Seshamma T; Pomerantz RJ; Department of Medicine, Jefferson Medical College, Philadelphia,; PA 19107.; The ability to detect a single copy of a specific gene in situ has many advantages and multiple applications in molecular biology, pathology and cell biology. We report here a unique, highly sensitive and specific technique which can be utilized to detect a single copy of human immunodeficiency virus type I (HIV-1) pr
Two-colour combination enzyme-linked immunosorbent assay for the simultaneous detection of HBV and HIV infection.: J Immunol Methods. 1993 Jan 14;158(1):95-106. Unique Identifier : AIDSLINE MED/93155497; Porstmann T; Nugel E; Henklein P; Dopel H; Ronspeck W; Pas P; von Baehr R; Department of Medical Immunology, Medical School Charite,; Humboldt University of Berlin, Germany.; To reduce the cost, time and waste in screening for HIV and HBV infections a combined assay for HIV-1 and -2 antibodies and HBsAg has been developed. Monoclonal anti-HBs antibodies were co-immobilized with synthetic peptides representing immunodominant regions of HIV-1 and -2. The presence of anti-HIV antibodies in th
Expression and immunogenicity of the entire human T cell leukaemia virus type I envelope protein produced in a baculovirus system.: J Gen Virol. 1993 Feb;74 ( Pt 2):211-22. Unique Identifier : AIDSLINE MED/93155646; Arp J; Ford CM; Palker TJ; King EE; Dekaban GA; Immunology Group, John P. Robarts Research Institute, London,; Ontario, Canada.; The entire envelope gene of human T cell leukaemia virus type I (HTLV-I) has been successfully expressed in a baculovirus non-fusion vector system. The HTLV-I envelope protein accumulated within the insect cells as inclusion bodies which allowed efficient recovery of the recombinant protein. In an attempt to study the
Balint's syndrome in subacute HIV encephalitis [letter; comment]: J Neurol Neurosurg Psychiatry. 1993 Jan;56(1):115. Unique Identifier : AIDSLINE MED/93155671; Berger JR; Whigham TE
Functional sites in the 5' region of human immunodeficiency virus type 1 RNA form defined structural domains.: J Mol Biol. 1993 Jan 20;229(2):382-97. Unique Identifier : AIDSLINE MED/93156049; Baudin F; Marquet R; Isel C; Darlix JL; Ehresmann B; Ehresmann C; UPR 9002 du CNRS, Institut de Biologie Moleculaire et; Cellulaire, Strasbourg, France.; The 5 region of HIV-1 RNA contains functional elements involved in key steps of the retroviral cycle, such as genomic RNA transcription, splicing, translation, dimerization or initiation of reverse transcription. In the present work, we investigated the conformation of the first 500 nucleotides covering the RNA leade
The impact of human immunodeficiency virus on presentation and diagnosis of tuberculosis in a cohort study in Zambia.: J Trop Med Hyg. 1993 Feb;96(1):1-11. Unique Identifier : AIDSLINE MED/93156069; Elliott AM; Halwiindi B; Hayes RJ; Luo N; Tembo G; Machiels L; Bem C; Steenbergen G; Pobee JO; Nunn PP; et al; School of Medicine, University of Zambia, Lusaka.; Two hundred and forty-nine patients with tuberculosis were recruited to a cohort study to investigate the interaction between tuberculosis and HIV in Lusaka, Zambia ; findings at presentation are presented here. One hundred and eighty-two (73%; 95% confidence interval 67-79%) of the
From the Centers for Disease Control and Prevention. Sexual risk behaviors of STD clinic patients before and after Earvin 'Magic' Johnson's HIV-infection announcement--Maryland, 1991-1992.: JAMA. 1993 Feb 24;269(8):977-8. Unique Identifier : AIDSLINE MED/93156122
Over expression of insulin-like growth factor receptor type-I in T-cell lines infected with human T-lymphotropic virus types-I and II.: Leuk Res. 1993 Jan;17(1):31-5. Unique Identifier : AIDSLINE MED/93156341; Lal RB; Rudolph DL; Folks TM; Hooper WC; Retrovirus Diseases Branch, Centers for Disease Control, Atlanta,; GA 30333.; To determine if aberrant expression of tyrosine kinase growth factor receptors may be related to the cell transformation capabilities of human T-lymphotropic viruses (HTLVs), we examined the expression of the epidermal growth factor receptor (EGF-R), insulin receptor (INS-R), and insulin-like growth factor receptor ty
Characteristics of chemotherapy-induced clinical remission in long survivors with aggressive adult T-cell leukemia/lymphoma.: Leuk Res. 1993 Feb;17(2):157-66. Unique Identifier : AIDSLINE MED/93156358; Tsukasaki K; Ikeda S; Murata K; Maeda T; Atogami S; Sohda H; Momita S; Jubashi T; Yamada Y; Mine M; et al; Department of Hematology, Nagasaki University School of Medicine,; Japan.; The acute and lymphoma types of adult T-cell leukemia/lymphoma (ATL) usually have a very poor prognosis, although some patients achieve long survival after chemotherapy. A total of 114 patients with these aggressive types of ATL were newly diagnosed at our institution from 1975 to 1989. By multivariate analysis, poor
[Pharmacokinetic study of zidovudine in parenteral drug addicts with human immunodeficiency virus infection (see comments)]: Med Clin (Barc). 1993 Jan 16;100(2):46-9. Unique Identifier : AIDSLINE MED/93156377; Pachon J; Viciana P; Cisneros JM; Garcia Pesquera F; Castillo JR; Canas E; Unidad de Enfermedades Infecciosas, Hospital Universitario Virgen; del Rocio, Sevilla.; BACKGROUND: The aim of this study was to know the pharmacokinetics of zidovudine (ZDV) in steady state in patients with infection by the human immunodeficiency virus (HIV) in whom the risk factor was intravenous drug use. METHODS: The study was carried out in 8 patients in stage IV of the Centers for Disease Control (
[Prevalence of antibodies against hepatitis C virus in a sample of homosexual males (see comments)]: Med Clin (Barc). 1993 Jan 16;100(2):50-2. Unique Identifier : AIDSLINE MED/93156378; Morales MA; Pineda JA; Leal M; Pino R; Torronteras R; Sanchez-Quijano A; Lissen E; Departamento de Medicina Interna, Hospital Universitario Virgen; del Rocio, Sevilla.; BACKGROUND: The finding of an important proportion of cases of hepatitis C without previous contact with blood or hemoderivates has led to suspect that there may be other routes of transmission among which sexual transmission may be found. METHODS: The presence of antibodies against the hepatitis C virus (anti-HCV) an
[Candida albicans esophagitis in AIDS patients (letter; comment)]: Med Clin (Barc). 1993 Feb 13;100(6):237. Unique Identifier : AIDSLINE MED/93156404; Diz Dios P; Fernandez Feijoo J; Ocampo Hermida A; Miralles Alvarez C
[Filgrastim (rG-CSF) and neutropenia associated with AIDS, is MEDLINE lying? (letter; comment)]: Med Clin (Barc). 1993 Feb 13;100(6):238-9. Unique Identifier : AIDSLINE MED/93156405; Navarro FA
[Elevation of HIV-antigen concentration during administration of zidovudine (letter)]: Med Clin (Barc). 1993 Feb 13;100(6):239. Unique Identifier : AIDSLINE MED/93156406; Valencia ME; Gil A; Pintado V; Zapico RM
[Syphilis in the USA in the shade of AIDS. Most frequent among coloured crack addicts]: Lakartidningen. 1993 Jan 20;90(3):131-3. Unique Identifier : AIDSLINE MED/93156426; Lowhagen GB; Hudkliniken, Sahlgrenska sjukhuset, Goteborg.
Absence of monoclonal antibody detectable Kaposi sarcoma-specific antigens on lesion-derived cultured cells.: Life Sci. 1993;52(7):663-8. Unique Identifier : AIDSLINE MED/93156568; Bernas M; Enriquez J; Way D; Witte M; Ragland A; Bradley-Dunlop D; Fiala M; Department of Surgery, University of Arizona, Tucson 85724.; To define the histogenesis and cell origin of Kaposi sarcoma (KS), we cultured KS cells without retrovirally conditioned media from three HIV seropositive AIDS patients and then attempted to raise mouse hybrid monoclonal antibodies (Mabs) specific to these AIDS-KS cells. After both in vivo and in vitro immunization tr
Suicide among AIDS patients.: Med Sci Law. 1993 Jan;33(1):21-8. Unique Identifier : AIDSLINE MED/93156573; Copeland AR; Anderson Medical Center, Houston, TX.; I studied 25 cases of suicide in people diagnosed as having the acquired immunodeficiency syndrome (AIDS) or who thought that they had that disorder, during 1985-1989. Case reports are presented. A discussion ensues concerning the occurrence of this phenomenon and the medical examiner s role in AIDS public health sit
Update: availability of sulfadiazine--United States.: MMWR Morb Mortal Wkly Rep. 1993 Feb 12;42(5):105. Unique Identifier : AIDSLINE MED/93156665; Sulfadiazine is a sulfa drug commonly used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome (AIDS) and newborns with congenital infections. In December 1992, CDC reported that the domestic manufacturer of sulfadiazine had ceased production in October 1992 and
Business responds to AIDS program--December 1992-February 1993.: MMWR Morb Mortal Wkly Rep. 1993 Feb 12;42(5):95, 101. Unique Identifier : AIDSLINE MED/93156669; Of all acquired immunodeficiency syndrome (AIDS) cases reported through 1991 in the United States , 76% occurred among persons aged 25-44 years; persons aged 15-44 years comprise approximately 50% of the United States workforce. On December 1, 1992, CDC introduced Business Responds to A
HTLV-1 in acquired adult myopathy [see comments]: Muscle Nerve. 1993 Feb;16(2):162-5. Unique Identifier : AIDSLINE MED/93156749; Dickoff DJ; Simpson DM; Wiley CA; Mendelson SG; Farraye J; Wolfe DE; Wachsman W; Department of Neurology, Mount Sinai Medical Center, New York,; New York 10029.; We report a 53-year-old Jamaican man with 20 years of progressing weakness involving proximal limb muscles and neck flexors. Serum CK was 1100 IU/L. EMG demonstrated spontaneous activity, myopathic motor units, and full recruitment patterns in weak muscles. Muscle biopsy revealed marked myofiber degeneration with exte
Control of epidemics [letter; comment]: N Engl J Med. 1993 Mar 4;328(9):667. Unique Identifier : AIDSLINE MED/93156787; Sullivan L
Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds.: Nature. 1993 Feb 4;361(6411):473-5. Unique Identifier : AIDSLINE MED/93156817; Rice WG; Schaeffer CA; Harten B; Villinger F; South TL; Summers MF; Henderson LE; Bess JW Jr; Arthur LO; McDougal JS; et al; Laboratory of Antiviral Drug Mechanisms, Program Resources; Inc./DynCorp., National Cancer Institute-Frederick Cancer; Research and Development Center, Maryland 21702.; Retroviral nucleocapsid and gag-precursor proteins from all known strains of retroviruses contain one or two copies of an invariant sequence, Cys-X2-Cys-X4-His-X4-Cys, that is populated with zinc in mature particles. Modification of cysteine or histidine residues results in defective packaging of genomic viral RNA and
Understanding H.I.V. Why healthy cells self-destruct [news]: Nursing. 1993 Feb;23(2):51. Unique Identifier : AIDSLINE MED/93156952
Trends in AIDS mortality among residents of Puerto Rico and among Puerto Rican immigrants and other Hispanic residents of New York City, 1981-1989.: N Y State J Med. 1993 Jan;93(1):12-5. Unique Identifier : AIDSLINE MED/93156963; Menendez BS; Blum S; Singh TP; Drucker E; Department of Health Services, Lehman College, Bronx, NY 10468.; This study contrasts the acquired immunodeficiency syndrome mortality experience of residents of Puerto Rico with that of New York City residents identified as either Puerto Rico-born and non-Puerto Rico-born Hispanics. Portions of the mortality data examined in this investigat
Managing HIV-positive and AIDS risks: educational and psychosocial resource assessment.: Nurs Manage. 1993 Feb;24(2):48-53. Unique Identifier : AIDSLINE MED/93157002; Raffin RA; Gillies DA; Hough EE; Biordi DL; A needs assessment survey reveals many staff nurses incorrectly estimate the HIV contagion risk, inadequately follow universal precaution mandates, and are often unaware of available information and counseling resources. Nurses want current, reliable HIV-AIDS related information and counseling from credible, accessibl
Questions and answers about AIDS.: Ohio Nurses Rev. 1993 Jan-Feb;68(1):13. Unique Identifier : AIDSLINE MED/93157035; Coleman D
The c-rel protooncogene product represses NF-kappa B p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus.: Proc Natl Acad Sci U S A. 1993 Feb 1;90(3):1023-7. Unique Identifier : AIDSLINE MED/93157335; Doerre S; Sista P; Sun SC; Ballard DW; Greene WC; Howard Hughes Medical Institute, Duke University Medical Center,; Durham, NC 27710.; The long terminal repeat (LTR) of the type 1 human immunodeficiency virus (HIV-1) and the 5 regulatory region of the gene encoding the interleukin 2 receptor alpha subunit (IL-2R alpha) share functional kappa B enhancer elements involved in the regulation of these inducible transcription units during T-cell activatio
Proton MR spectroscopy of HIV-infected patients: characterization of abnormalities with imaging and clinical correlation.: Radiology. 1993 Mar;186(3):739-44. Unique Identifier : AIDSLINE MED/93157585; Jarvik JG; Lenkinski RE; Grossman RI; Gomori JM; Schnall MD; Frank I; Department of Radiology, Hospital of the University of; Pennsylvania, Philadelphia 19104.; The purpose of this study was to characterize the proton magnetic resonance (MR) spectroscopic findings in the brains of patients infected with human immunodeficiency virus (HIV). Peak areas were used to calculate metabolite ratios. Spectra were analyzed by blinded readers who calculated areas under metabolite peaks.
Human immunodeficiency virus infection: musculoskeletal manifestations.: Radiology. 1993 Mar;186(3):833-8. Unique Identifier : AIDSLINE MED/93157599; Steinbach LS; Tehranzadeh J; Fleckenstein JL; Vanarthos WJ; Pais MJ; Department of Radiology, University of California, San Francisco; 94143.; The authors retrospectively reviewed the charts, radiographs, and other accompanying imaging studies of 45 patients with musculoskeletal abnormalities associated with human immunodeficiency virus (HIV) infection. These included 19 patients with osseous infection, including eight with osteomyelitis, seven with
[Prison, drug addicts and AIDS (editorial)]: Recenti Prog Med. 1993 Jan;84(1):1-4. Unique Identifier : AIDSLINE MED/93157711; De Cataldo G
[AIDS patients in Italian prisons: a burning issue with no easy solution (editorial)]: Recenti Prog Med. 1993 Jan;84(1):57-63. Unique Identifier : AIDSLINE MED/93157721; Ippolito G; Some of the problems related to the detention of HIV infected subjects in Italian prisons are discussed, with particular reference to subjects with AIDS. The Italian Department of Penitentiary Administration reported, in 1991, the presence of 3030 HIV infected subjects, out of which 84 with AIDS. These subjects amount
Toxoplasmic encephalitis in the AIDS patient.: Rehabil Nurs. 1993 Jan-Feb;18(1):20-2, 25. Unique Identifier : AIDSLINE MED/93157726; Mocsny N; Toxoplasmic encephalitis is recognized as a major cause of opportunistic infection of the central nervous system in patients with acquired immune deficiency syndrome (AIDS). Often this protozoal infection is benign, but in the AIDS patient it can cause life-threatening complications. Usually, toxoplasmic encephalitis
NIH panics over AIDS 'Manhattan Project' [news]: Science. 1993 Jan 29;259(5095):587. Unique Identifier : AIDSLINE MED/93157813; Stone R
Agencies spar over vaccine trial [news]: Science. 1993 Feb 5;259(5096):752-3. Unique Identifier : AIDSLINE MED/93157838; Cohen J
AIDS research. Reorganization plan draws fire at NIH [news]: Science. 1993 Feb 5;259(5096):753-4. Unique Identifier : AIDSLINE MED/93157839; Cohen J
Factors associated with condom use in a high-risk heterosexual population.: Sex Transm Dis. 1993 Jan-Feb;20(1):14-20. Unique Identifier : AIDSLINE MED/93157873; Weinstock HS; Lindan C; Bolan G; Kegeles SM; Hearst N; Division of STD/HIV Prevention, Centers for Disease Control,; Atlanta, Georgia 30333.; The use of condoms has been advocated as a means of preventing the transmission of the human immunodeficiency virus and other sexually transmitted agents. To better understand factors that may influence condom use, 300 heterosexuals were enrolled in a cross-sectional study of patients attending San Francisco s only pu
Virucides in prevention of HIV infection. Research Priorities. World Health Organization Working Group on Virucides.: Sex Transm Dis. 1993 Jan-Feb;20(1):41-4. Unique Identifier : AIDSLINE MED/93157877; Rosenberg MJ; Holmes KK; World Health Organization Working Group on Virucides, Geneva,; Switzerland.; Vaginal spermicides have microbicidal properties that suggest their usefulness in helping to protect against human immunodeficiency virus (HIV) and other sexually transmitted infections. Laboratory, animal, and clinical investigations also support this notion. Because of the importance of identifying additional method
Factors correlated with homosexually acquired human immunodeficiency virus infection in the era of safer sex. Was the prevention message clear and well understood? Alain Brugeat Physician Group.: Sex Transm Dis. 1993 Jan-Feb;20(1):51-8. Unique Identifier : AIDSLINE MED/93157880; Messiah A; Bucquet D; Mettetal JF; Larroque B; Rouzioux C; Service de Sante Publique et d'Epidemiologie, Hopital de; Bicetre, Le Kremlin-Bicetre, France.; A cross-sectional survey was conducted between November 1986 and January 1988 among 246 homosexual/bisexual patients by consulting physicians promoting human immunodeficiency virus (HIV) infection prevention, to determine factors correlated with HIV infection a few years after the launch of safer sex recommendations.
Agenda on AIDS.: Tex Med. 1993 Feb;89(2):28. Unique Identifier : AIDSLINE MED/93157922; Albrecht LJ
Transfusion and the human immunodeficiency virus [editorial; comment]: Transfusion. 1993 Feb;33(2):101-2. Unique Identifier : AIDSLINE MED/93158038; Balfour HH Jr
Human T-cell lymphotropic virus type I and II DNA amplification in seropositive and seronegative at-risk individuals [see comments]: Transfusion. 1993 Feb;33(2):106-10. Unique Identifier : AIDSLINE MED/93158040; de Montalembert M; Wattel E; Lefrere F; Mariotti M; Agis F; Ferrer-le-Coeur F; Girot R; Lefrere JJ; Molecular Biology Laboratory, National Institute of Blood; Transfusion, Hospital Saint-Antoine, Paris, France.; To determine the presence or the absence of human T-lymphotropic virus type I and/or II (HTLV-I/II) DNA in at-risk individuals who were persistently negative for specific serologic assays, polymerase chain reaction with two primer pairs in common and conserved regions of HTLV-I and -II genomes was used. Seronegative i
Early transfusion and length of survival in acquired immune deficiency syndrome: experience with a population receiving medical care at a public hospital [see comments]: Transfusion. 1993 Feb;33(2):111-8. Unique Identifier : AIDSLINE MED/93158041; Vamvakas E; Kaplan HS; Department of Pathology, New York University Medical Center, New; York.; An extensive body of literature has attributed an immunosuppressive, and potentially deleterious, effect to blood transfusion. The possibility of a deleterious effect of transfusion on the subsequent survival of acquired immune deficiency syndrome (AIDS) patients was investigated in a public hospital-based cohort of 5
Human immunodeficiency virus type 1 nucleic acids detected before p24 antigenemia in a blood donor.: Transfusion. 1993 Feb;33(2):164-7. Unique Identifier : AIDSLINE MED/93158051; de Saussure P; Yerly S; Tullen E; Perrin LH; Central Laboratory of Virology, Geneva University Hospital,; Switzerland.; A blood donation from a 46-year-old homosexual man was discarded because of elevated alanine aminotransferase levels. Thirteen days later, the patient presented with symptomatic primary human immunodeficiency virus type 1 (HIV-1) infection. Virologic investigations were performed retrospectively on blood samples (incl
[Distribution of free equipment to intravenous drug addicts in Copenhagen]: Ugeskr Laeger. 1993 Jan 25;155(4):227-31. Unique Identifier : AIDSLINE MED/93158090; Svendsen RN; Kofod S; Istedgades Apotek, Kobenhavn.; Since HIV-infection was recognized in Denmark in the middle of the 80 ies, the authorities have tried to prevent spread of the infection by common educational information. Besides this, special interest was focussed on transmission
Antiviral agents: characteristic activity spectrum depending on the molecular target with which they interact.: Adv Virus Res. 1993;42:1-55. Unique Identifier : AIDSLINE MED/93158382; De Clercq E; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.; The target protein (enzyme) with which antiviral agents interact determines their antiviral activity spectrum. Based on their activity spectrum, antiviral compounds could be divided into the following classes: (1) sulfated polysaccharides (i.e., dextran sulfate), which interact with the viral envelope glycoproteins an
Human immunodeficiency virus vaccines.: Adv Virus Res. 1993;42:103-48. Unique Identifier : AIDSLINE MED/93158383; Bolognesi DP; Duke Center for AIDS Research, Duke University Medical Center,; Durham, North Carolina 27710.
AIDS-related lymphoma: an unusual cause of omental caking [letter]: AJR Am J Roentgenol. 1993 Mar;160(3):661. Unique Identifier : AIDSLINE MED/93158464; Maya MM; Fried K; Gendal ES
Frequency of left ventricular dysfunction and other echocardiographic abnormalities in human immunodeficiency virus seronegative intravenous drug users.: Am J Cardiol. 1993 Feb 15;71(5):446-7. Unique Identifier : AIDSLINE MED/93158538; Willoughby SB; Vlahov D; Herskowitz A; School of Public Health and Hygiene, Department of Immunology and; Infectious Diseases, Johns Hopkins Medical Institutions,; Baltimore, Maryland 21205.
Human immunodeficiency virus infection and glomerular disease [letter; comment]: Am J Kidney Dis. 1993 Feb;21(2):236. Unique Identifier : AIDSLINE MED/93158595; Appel RG
Hyponatremia in hospitalized patients with the acquired immunodeficiency syndrome (AIDS) and the AIDS-related complex.: Am J Med. 1993 Feb;94(2):169-74. Unique Identifier : AIDSLINE MED/93158633; Tang WW; Kaptein EM; Feinstein EI; Massry SG; Division of Nephrology, University of Southern California, Los; Angeles.; STUDY OBJECTIVE: To determine the frequency, etiology, and clinical association of hyponatremia in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex (ARC). PATIENTS AND METHODS: A prospective analysis of 167 patients with AIDS and 45 patients with ARC admitted on 259 occasions to a l
Spontaneous ulcerative keratitis in immunocompromised patients.: Am J Ophthalmol. 1993 Feb 15;115(2):202-8. Unique Identifier : AIDSLINE MED/93158656; Aristimuno B; Nirankari VS; Hemady RK; Rodrigues MM; Department of Ophthalmology, University of Maryland School of; Medicine, Baltimore.; We studied the occurrence of ulcerative keratitis in five eyes of four patients who were examined at the University of Maryland Hospital ophthalmology clinic over a 12-month period. All were young women who were intravenous drug abusers, with no known predisposing factors for ulcerative keratitis. Two patients had acq
Pneumocystis carinii pneumonia presenting as asthma: increased bronchial hyperresponsiveness in Pneumocystis carinii pneumonia.: Ann Allergy. 1993 Feb;70(2):141-6. Unique Identifier : AIDSLINE MED/93158939; Schnipper S; Small CB; Lehach J; Kaufman A; Grizzanti JN; Rothstein M; Minkowitz S; Rosenstreich DL; Department of Medicine, Albert Einstein College of Medicine,; Bronx, New York 10461.; Two male patients presented with clinical and laboratory findings consistent with typical bronchial asthma and subsequently developed Pneumocystis carinii pneumonia (PCP). Only on subsequent questioning did both admit to homosexuality and behavior associated with a high risk of HIV-infection. In order to determine how
Pertussis is rare in human immunodeficiency virus disease.: Am Rev Respir Dis. 1993 Feb;147(2):411-3. Unique Identifier : AIDSLINE MED/93158999; Cohn SE; Knorr KL; Gilligan PH; Smiley ML; Weber DJ; Infectious Diseases Unit, University of Rochester Medical Center,; NY 14642.; Many adults are susceptible to pertussis, and Bordetella pertussis has been isolated from five patients with HIV disease. The prevalence of B. pertussis in 60 HIV-infected adults with nasopharyngeal (NP) swab cultures were studied and questionnaires were used that assessed HIV-related risk behaviors and disease status
Syndrome of Rochalimaea henselae adenitis suggesting cat scratch disease [see comments]: Ann Intern Med. 1993 Mar 1;118(5):331-6. Unique Identifier : AIDSLINE MED/93159015; Dolan MJ; Wong MT; Regnery RL; Jorgensen JH; Garcia M; Peters J; Drehner D; Wilford Hall USAF Medical Center, Lackland AFB, Texas.; OBJECTIVE: To describe a clinical syndrome of cat scratch disease caused by Rochalimaea henselae, including methods for isolation of the organism from tissue and for identification. DESIGN: Case series. SETTING: U.S. Air Force referral hospital infectious diseases clinic. PATIENTS: Two previously healthy patients. MAI
Pneumococcal disease and HIV infection [letter; comment]: Ann Intern Med. 1993 Mar 1;118(5):393; discussion 394. Unique Identifier : AIDSLINE MED/93159026; Gilks CF
Pneumococcal disease and HIV infection [letter; comment]: Ann Intern Med. 1993 Mar 1;118(5):393-4. Unique Identifier : AIDSLINE MED/93159027; Klenerman P; Luzzi GA; Peto TE
Cotrimoxazole prophylaxis for toxoplasmosis [letter; comment]: Ann Intern Med. 1993 Mar 1;118(5):395. Unique Identifier : AIDSLINE MED/93159029; Caumes E; Lheriteau F; Gentilini M
Central nervous system infection with Mycobacterium kansasii [letter]: Ann Intern Med. 1993 Mar 1;118(5):396. Unique Identifier : AIDSLINE MED/93159031; Bergen GA; Yangco BG; Adelman HM
In vitro activities of nucleoside analog antiviral agents against salmonellae.: Antimicrob Agents Chemother. 1993 Jan;37(1):106-10. Unique Identifier : AIDSLINE MED/93159125; Sperber SJ; Feibusch EL; Damiani A; Weinstein MP; Department of Medicine, UMDNJ-Robert Wood Johnson Medical School,; New Brunswick 08903-0019.; Zidovudine (ZDV) has antibacterial activity against many members of the family Enterobacteriaceae, including Salmonella species, and may be responsible for a decrease in the frequency of salmonellosis in persons infected with human immunodeficiency virus (HIV). Other nucleoside analogs, such as didanosine (2 ,3 -dideo
Preclinical evaluation of antiviral activity and toxicity of Abbott A77003, an inhibitor of the human immunodeficiency virus type 1 protease.: Antimicrob Agents Chemother. 1993 Jan;37(1):115-9. Unique Identifier : AIDSLINE MED/93159127; Kort JJ; Bilello JA; Bauer G; Drusano GL; Department of Pathology, School of Medicine, University of; Maryland, Baltimore 21201.; A synthetic, symmetry-based inhibitor of the human immunodeficiency virus type 1 (HIV-1) protease, A77003, was evaluated for antiviral activity and cytotoxicity in vitro in human peripheral blood lymphocytes or cell lines H9, CEM, and U937. Toxicity and antiviral activity of the HIV-1 protease inhibitor were compared
Evaluation of synergy between carbovir and 3'-azido-2',3'-deoxythymidine for inhibition of human immunodeficiency virus type 1.: Antimicrob Agents Chemother. 1993 Jan;37(1):144-7. Unique Identifier : AIDSLINE MED/93159137; Smith MS; Kessler JA; Rankin CD; Pagano JS; Kurtzberg J; Carter SG; Lineberger Comprehensive Cancer Research Center, University of; North Carolina, Chapel Hill 27599-7295.; 3 -Azido-2 ,3 -deoxythymidine and carbovir [racemic and (-) enantiomer] were evaluated individually and in combination for antiviral activity against human immunodeficiency virus type 1 replication and cytotoxicity in vitro. The combination of these drugs synergistically inhibited human immunodeficiency virus type 1 r
In vitro antimicrobial activity of benzoxazinorifamycin, KRM-1648, against Mycobacterium avium complex, determined by the radiometric method.: Antimicrob Agents Chemother. 1993 Jan;37(1):67-70. Unique Identifier : AIDSLINE MED/93159147; Tomioka H; Saito H; Fujii K; Sato K; Hidaka T; Department of Microbiology and Immunology, Shimane Medical; University, Japan.; MICs of a newly developed benzoxazinorifamycin derivative, KRM-1648, for Mycobacterium avium complex (MAC) were determined by the BACTEC 460 TB system and compared with those of other known antimicrobial agents. The radiometric method gave a fast, accurate, and reproducible MIC for each antimicrobial agent. MICs of KR
Universal precautions: providing a basis for HIV infection control guidelines.: ANNA J. 1993 Feb;20(1):104, 103. Unique Identifier : AIDSLINE MED/93159174; Scherting D
Treatment of AIDS-related bronchopleural fistula by pleurectomy [letter; comment]: Ann Thorac Surg. 1993 Feb;55(2):565-6. Unique Identifier : AIDSLINE MED/93159242; Olivier HF Jr
Safety of intravenous immunoglobulin [editorial]: Arch Neurol. 1993 Feb;50(2):135-6. Unique Identifier : AIDSLINE MED/93159344; Thornton CA; Ballow M
Measuring performance decrements in aviation personnel infected with the human immunodeficiency virus.: Aviat Space Environ Med. 1993 Feb;64(2):158-64. Unique Identifier : AIDSLINE MED/93159409; Mapou RL; Kay GG; Rundell JR; Temoshok L; Military Medical Consortium for Applied Retroviral Research,; Henry M. Jackson Foundation for the Advancement of Military; Medicine, Rockville, MD 20850.; There is controversy over whether cognitive impairment occurs in early human immunodeficiency virus (HIV) disease. When impairment is reported, findings are typically subclinical, affect only a minority, and their relationship to occupational functioning has not been established. Despite such findings, it has been rec
Asymptomatic HIV-1 infection and aviation safety [letter; comment]: Aviat Space Environ Med. 1993 Feb;64(2):172-5. Unique Identifier : AIDSLINE MED/93159412; Selnes OA; Miller EN
Molecular dynamics simulation of HIV-1 protease in a crystalline environment and in solution [published erratum appears in Biochemistry 1993 Mar 30;32(12):3196]: Biochemistry. 1993 Feb 16;32(6):1443-53. Unique Identifier : AIDSLINE MED/93160180; York DM; Darden TA; Pedersen LG; Anderson MW; Laboratory of Molecular Toxicology, National Institute of; Environmental Health Sciences, Research Triangle Park, North; Carolina 27709.; Simulations of the unbound form of the human immunodeficiency virus type 1 protease have been carried out to 200 ps in a crystalline environment and in solution. Solution simulations were performed with and without charge-balancing counterions. The results are compared with the 2.8-A crystallographic structure of Wlod
Didanosine-associated eosinophilia with acute thrombocytopenia.: Ann Pharmacother. 1993 Jan;27(1):23-5. Unique Identifier : AIDSLINE MED/93160582; Lor E; Liu YQ; San Francisco General Hospital, Department of Pharmaceutical; Services, CA 94110.; OBJECTIVE: To report a case of didanosine (ddI)-induced acute thrombocytopenia and to discuss the incidence of this occurrence. CASE SUMMARY: A 42-year-old man was admitted to the hospital on November 21, 1991, with acute thrombocytopenia. The patient had an AIDS index diagnosis of Kaposi s sarcoma (KS) in 1988 and ha
Antifungal prophylaxis in immunocompromised hosts.: Ann Pharmacother. 1993 Jan;27(1):53-60. Unique Identifier : AIDSLINE MED/93160593; Reents S; Goodwin SD; Singh V; Department of Pharmacy, Shands Hospital, University of Florida,; Gainesville 32610.; OBJECTIVE: To review the literature on the efficacy and safety of antifungal agents for prophylaxis of fungal infections in populations of immunocompromised hosts (key words: hematology-oncology, surgical, solid organ transplant, HIV infection), and to develop guidelines and recommendations regarding safe and effectiv
A stochastic model of the HIV epidemic and the HIV infection distribution in a homosexual population.: Math Biosci. 1993 Jan;113(1):115-43. Unique Identifier : AIDSLINE MED/93160637; Tan WY; Byers RH Jr; Department of Mathematical Sciences, Memphis State University,; Tennessee.; In this paper we develop a stochastic model for the HIV epidemic in a homosexual population and use the model to characterize the HIV infection distribution and seroconversion distribution. Through computer-generated infection distributions and seroconversion distributions, we assess the effects of various risk factor
The health of the nation. HIV/AIDS and sexual health [editorial]: Br J Hosp Med. 1993 Jan 6-19;49(1):21, 24-5. Unique Identifier : AIDSLINE MED/93161025; Adler M; Johnson A
Disseminated cutaneous infection due to Mycobacterium tuberculosis in a person with AIDS [see comments]: Can Med Assoc J. 1993 Feb 15;148(4):577-8. Unique Identifier : AIDSLINE MED/93161171; Bassiri A; Chan NB; McLeod A; Rossi S; Phillips P; Department of Medicine, St. Paul's Hospital, Vancouver, BC.
HIV and Canada's hemophiliacs: looking back at a tragedy [see comments]: Can Med Assoc J. 1993 Feb 15;148(4):609-12. Unique Identifier : AIDSLINE MED/93161176; Dunn K
When science and passion meet: the impact of AIDS on research.: Can Med Assoc J. 1993 Feb 15;148(4):638-42. Unique Identifier : AIDSLINE MED/93161182; Pripstein J; McGill University.
Primary T-cell lymphoma of the gastrointestinal tract associated with human T-cell lymphotropic virus type I. An analysis using in situ hybridization and polymerase chain reaction.: Cancer. 1993 Feb 1;71(3):708-16. Unique Identifier : AIDSLINE MED/93161237; Tokunaga O; Watanabe T; Shimamoto Y; Tokudome S; Department of Pathology, Saga Medical School, Japan.; BACKGROUND. During a population-based local cancer registry, a peculiar type of T-cell lymphoma restricted to the gastrointestinal tract was found in patients living in southwestern Japan . METHODS. Five cases of gastrointestinal (GI) tract T-cell lymphoma were analyzed with immunohi
Nonradioactive, colorimetric microplate hybridization assay for detecting amplified human immunodeficiency virus DNA.: Clin Chem. 1993 Feb;39(2):244-7. Unique Identifier : AIDSLINE MED/93161534; Rapier JM; Villamarzo Y; Schochetman G; Ou CY; Brakel CL; Donegan J; Maltzman W; Lee S; Kirtikar D; Gatica D; Division of HIV/AIDS, Centers for Disease Control, Atlanta, GA; 30333.; A nonradioactive, colorimetric microplate hybridization procedure was used to assay human immunodeficiency virus (HIV) DNA, amplified by the polymerase chain reaction (PCR). Under the PCR conditions used, four proviral copies per 150,000 cells were detected by amplifying a series of DNA mixtures that contained various
Time-resolved immunofluorometric assay of complement C3: application to cerebrospinal fluid.: Clin Chem. 1993 Feb;39(2):309-12. Unique Identifier : AIDSLINE MED/93161547; Gaillard O; Meillet D; Diemert MC; Musset L; Delattre J; Schuller E; Galli J; Laboratoire d'Immunochimie, Hopital de la Salpetriere, Paris,; France.; Complement components have a role in various neurological disorders. Complement C3 can be measured by immunochemical methods, but only radioimmunoassays and electroimmunodiffusion assays (EIDs) are sufficiently sensitive to be applied to biological fluids in which the C3 concentration is low, especially cerebrospinal
Recurrent parotitis in childhood [letter; comment]: Clin Pediatr (Phila). 1993 Feb;32(2):127. Unique Identifier : AIDSLINE MED/93161649; Katz BZ
Specificity and sensitivity of distinctive chest radiographic and/or 67Ga images in the noninvasive diagnosis of sarcoidosis.: Chest. 1993 Feb;103(2):403-9. Unique Identifier : AIDSLINE MED/93161733; Sulavik SB; Spencer RP; Palestro CJ; Swyer AJ; Teirstein AS; Goldsmith SJ; Division of Pulmonary Medicine, University of Connecticut Health; Center, Farmington.; An analysis of gallium-67 (67Ga) uptake in the lacrimal and salivary glands and intrathoracic lymph nodes was made in 162 patients with sarcoidosis, consisting of a large number with chronic fibrotic disease, and 167 HIV-positive patients (most of whom have/had AIDS). This study was designed to further assess the diag
Lung cancer in patients with immunodeficiency syndrome.: Chest. 1993 Feb;103(2):410-3. Unique Identifier : AIDSLINE MED/93161734; Karp J; Profeta G; Marantz PR; Karpel JP; Montefiore Medical Center, New York, Bronx 10467.; We report adenocarcinoma of the lung in seven patients with human immunodeficiency virus (HIV) infection. We compared age, clinical findings and survival data with a sex-matched control group of HIV-negative patients with adenocarcinoma of the lung. Median age of HIV-infected patients with lung cancer was lower than i
Increased Pneumocystis carinii recovery from the upper lobes in Pneumocystis pneumonia. The effect of aerosol pentamidine prophylaxis.: Chest. 1993 Feb;103(2):426-32. Unique Identifier : AIDSLINE MED/93161738; Baughman RP; Dohn MN; Shipley R; Buchsbaum JA; Frame PT; Department of Medicine, University of Cincinnati Medical Service.; STUDY OBJECTIVE: To determine the relative distribution of Pneumocystis carinii in the lungs of patients with P carinii pneumonia and to see the effect of aerosol pentamidine prophylaxis on this distribution. DESIGN: A prospective study of all human immunodeficiency virus-infected patients with pulmonary symptoms over
Acquired immunodeficiency syndrome-related visceral leishmaniasis presenting in a pleural effusion.: Chest. 1993 Feb;103(2):648-9. Unique Identifier : AIDSLINE MED/93161791; Chenoweth CE; Singal S; Pearson RD; Betts RF; Markovitz DM; Department of Internal Medicine, University of Michigan, Ann; Arbor.; Visceral leishmaniasis is increasingly reported in immunocompromised patients, including patients with AIDS. We report a case of visceral leishmaniasis in an AIDS patient who presented with pulmonary symptoms and bilateral pleural effusions. Histologic evaluation of pleural fluid and bone marrow revealed histiocytes w
Microscopic analysis of interactions between HIV particles and living leukocytes.: Cytometry. 1993;14(1):16-22. Unique Identifier : AIDSLINE MED/93161869; Wang T; Petty HR; Department of Biological Sciences, Wayne State University,; Detroit, Michigan 48202.; Video-enhanced/-intensified optical microscopy has been used to study the interaction of non-infectious HIV8E5 particles with living cells. The purified particles retained gp120 antigenic sites. Fluorescent lipids were intercalated into the particles envelopes. When incubated with CD4+ cell lines, roughly 90% of the
Studies on production of anticollagen antibodies in silicosis.: Environ Res. 1993 Jan;60(1):12-29. Unique Identifier : AIDSLINE MED/93162010; Nagaoka T; Tabata M; Kobayashi K; Okada A; First Department of Internal Medicine, Kanazawa University,; Japan.; Silicosis is characterized by pulmonary fibrotic changes which consist primarily of an increase in collagen. In this study, anticollagen antibodies in the serum of 134 silicosis patients versus 40 normal subjects were examined and their relationship with immunoglobulin, autoantibodies, and procollagen III peptide (PII
Familial primary gastric lymphoma.: Gut. 1993 Jan;34(1):136-40. Unique Identifier : AIDSLINE MED/93162499; Hayoz D; Extermann M; Odermatt BF; Pugin P; Regamey C; Knecht H; Institute of Biochemistry, University of Lausanne, Switzerland.; Familial lymphoma is uncommon and is usually associated with various forms of hereditary immunodeficiencies. Primary gastric lymphomas that occurred in three adults from the same family, who had no overt immunodeficiency or cancer of non-lymphomatous origin, are reported. Two sisters presented with a low grade lymphom
Resilience in adversity among long-term survivors of AIDS [published erratum appears in Hosp Community Psychiatry 1993 Apr;44(4):371]: Hosp Community Psychiatry. 1993 Feb;44(2):162-7. Unique Identifier : AIDSLINE MED/93162607; Rabkin JG; Remien R; Katoff L; Williams JB; Department of Psychiatry, Columbia University College of; Physicians and Surgeons, New York, NY.; OBJECTIVE: This study evaluated psychological and behavioral aspects of quality of life and medical care utilization in a population of gay men whose intake records at a New York City agency indicated the presence of an AIDS-defining opportunistic infection at least three years before entry into the study. METHODS: Fi
AIDS and child sexual abuse [letter; comment]: Hosp Community Psychiatry. 1993 Feb;44(2):186. Unique Identifier : AIDSLINE MED/93162615; Gellert GA; Durfee MJ; Berkowitz CD; Higgins KV; Tubiolo VC
Nucleotide sequence analysis and serologic characterization of a 27-kilodalton Mycobacterium intracellulare lipoprotein.: Infect Immun. 1993 Mar;61(3):1074-81. Unique Identifier : AIDSLINE GENBANK/L08229; Nair J; Rouse DA; Morris SL; Laboratory of Mycobacteria, Center for Biologics Evaluation and; Research, Food and Drug Administration, Bethesda, Maryland 20892.; Disseminated mycobacteremia resulting from Mycobacterium avium-Mycobacterium intracellulare complex (MAC) infections frequently contribute to the morbidity and mortality seen in AIDS patients. To better understand the immunopathology of MAC disease and to identify molecules that may have potential diagnostic and vacci
Cell therapy is being tested in the fight against the acquired immunodeficiency syndrome [editorial]: J Am Osteopath Assoc. 1993 Feb;93(2):194. Unique Identifier : AIDSLINE MED/93162972
Skin manifestations of human immunodeficiency virus (HIV): Part 2. Noninfectious skin manifestations.: J Am Osteopath Assoc. 1993 Feb;93(2):223-9. Unique Identifier : AIDSLINE MED/93162976; Kurgis BS; The incidence of the acquired immunodeficiency syndrome (AIDS) is rising at an alarming rate. Usually, the first clue that a patient has human immunodeficiency (HIV) infection is the emergence of a skin disease. Early diagnosis and aggressive therapy are vital in the management of these conditions. In Part 1 of this a
New HIV plaque titration; application to the assay of neutralizing antibody.: J Virol Methods. 1993 Jan;41(1):47-57. Unique Identifier : AIDSLINE MED/93163183; Tsunetsugu-Yokota Y; Ohshima M; Naito A; Chermann JC; Shih J; Yoshikura H; Department of Immunology, National Institute of Health, Tokyo,; Japan.; A simple, sensitive and accurate plaque assay was developed using HPB-Ma, a variant of the human T-cell line HPB-ALL, which becomes adherent to the substratum after infection with an amphotropic murine sarcoma virus (MSVa). The simplicity of this novel plaque assay allowed us to examine a large number of serum samples
Evaluation of an immunoblot assay for serological confirmation and differentiation of human T-cell lymphotropic virus types I and II.: J Clin Microbiol. 1993 Feb;31(2):260-4. Unique Identifier : AIDSLINE MED/93163261; Roberts BD; Foung SK; Lipka JJ; Kaplan JE; Hadlock KG; Reyes GR; Chan L; Heneine W; Khabbaz RF; Division of Viral and Rickettsial Diseases, Centers for Disease; Control, Atlanta, Georgia 30333.; The confirmation of infection with human T-cell lymphotropic virus type I (HTLV-I) and type II (HTLV-II) currently involves multiple assays. These include Western blot (immunoblot) (WB) and/or radioimmunoprecipitation assay for detection of antibodies to HTLV-specific viral proteins and polymerase chain reaction and/o
Comparison of four decontamination methods for recovery of Mycobacterium avium complex from stools.: J Clin Microbiol. 1993 Feb;31(2):302-6. Unique Identifier : AIDSLINE MED/93163269; Yajko DM; Nassos PS; Sanders CA; Gonzalez PC; Reingold AL; Horsburgh CR Jr; Hopewell PC; Chin DP; Hadley WK; Department of Laboratory Medicine, San Francisco General; Hospital, University of California 94110.; The presence of Mycobacterium avium complex (MAC) in stool specimens may be a predictor of disseminated MAC infection, yet the methods for decontaminating stools have not been evaluated for their usefulness in recovering MAC organisms. In the present study, four decontamination methods commonly used to recover acid-fa
Serotyping of Cryptococcus neoformans by using a monoclonal antibody specific for capsular polysaccharide.: J Clin Microbiol. 1993 Feb;31(2):359-63. Unique Identifier : AIDSLINE MED/93163280; Dromer F; Gueho E; Ronin O; Dupont B; Unite de Mycologie, Institut Pasteur, Paris, France.; The importance of epidemiological studies of cryptococcosis has increased since the beginning of the AIDS epidemic. Cryptococcus neoformans exists in two varieties defining four serotypes, Cryptococcus neoformans var. neoformans (serotypes A and D) and Cryptococcus neoformans var. gattii (serotypes B and C). The varie
Incidental finding of a microsporidian parasite from an AIDS patient.: J Clin Microbiol. 1993 Feb;31(2):436-9. Unique Identifier : AIDSLINE MED/93163298; McDougall RJ; Tandy MW; Boreham RE; Stenzel DJ; O'Donoghue PJ; Microbiology Department, Drs. Sullivan, Nicolaides and Partners,; Taringa, Brisbane, Australia.; Light microscopic examination of feces from a human immunodeficiency virus-positive patient with chronic diarrhea, anorexia, and lethargy revealed the presence of numerous refractile bodies resembling microsporidian spores. They were subsequently identified as belonging to the genus Nosema on the basis of their ultras
Clinical features of inflammatory dermatoses in human immunodeficiency virus type 1 disease and their correlation with Walter Reed stage. Military Medical Consortium for Applied Retroviral Research.: J Am Acad Dermatol. 1993 Feb;28(2 Pt 1):167-73. Unique Identifier : AIDSLINE MED/93163429; Smith KJ; Skelton HG; Yeager J; Baxter D; Angritt P; Johnson S; Oster CN; Wagner KF; Department of Dermatopathology, Armed Forces Institute of; Pathology, Washington, DC 20306.; BACKGROUND: As part of a military study of the natural history of human immunodeficiency virus type 1 (HIV-1) disease, all patients entered in the study were examined for cutaneous changes associated with HIV-1 infection. OBJECTIVE: Our purpose was to characterize and record the types of inflammatory dermatoses in a l
Histopathologic and immunohistochemical findings associated with inflammatory dermatoses in human immunodeficiency virus type 1 disease and their correlation with Walter Reed stage. Military Medical Consortium for Applied Retroviral Research.: J Am Acad Dermatol. 1993 Feb;28(2 Pt 1):174-84. Unique Identifier : AIDSLINE MED/93163430; Smith KJ; Skelton HG; Yeager J; Angritt P; Frisman D; Wagner KF; Baxter D; James WD; Oster CN; Armed Forces Institute of Pathology, Department of; Dermatopathology, Washington, DC 20306.; BACKGROUND: Cutaneous lesions are common in patients with human immunodeficiency virus type 1 (HIV-1) infection. In many cases they are nonspecific inflammatory dermatoses. OBJECTIVE: Our goal was to determine whether features of these inflammatory dermatoses were characteristic of HIV-1 infection and whether the chan
Acute pustular eruption: an unusual clinical feature of disseminated mycobacterial infection in patients with acquired immunodeficiency syndrome.: J Am Acad Dermatol. 1993 Feb;28(2 Pt 1):264-6. Unique Identifier : AIDSLINE MED/93163448; Joly P; Picard-Dahan C; Bamberger N; Bouvet E; Salmon D; Grossin M; Belaich S; Department of Dermatology, Hopital Bichat Claude Bernard, Paris,; France.
Thalidomide: treatment of choice for aphthous ulcers in patients seropositive for human immunodeficiency virus.: J Am Acad Dermatol. 1993 Feb;28(2 Pt 1):271-2. Unique Identifier : AIDSLINE MED/93163451; Ghigliotti G; Repetto T; Farris A; Roy MT; De Marchi R; Division of Dermatology, S. Martino Hospital, Genoa, Italy.
Opportunistic infections of the oesophagus in AIDS patients: clinical and therapeutic problems [see comments]: J Intern Med. 1993 Feb;233(2):107-10. Unique Identifier : AIDSLINE MED/93163746; Bianchi Porro G; Parente F; Gastrointestinal Unit, L. Sacco Hospital, Milan, Italy.; The gastrointestinal tract is frequently involved in the acquired immunodeficiency syndrome. One of the most common digestive manifestations is dysphagia/odynophagia which constitutes the presenting feature of the syndrome in a number of patients and occurs in many others during the subsequent phases of the illness. I
Electron microscopy of rectal biopsies in HIV-positive individuals.: J Pathol. 1993 Jan;169(1):79-87. Unique Identifier : AIDSLINE MED/93163974; Blanshard C; Ellis DS; Tovey G; Gazzard BG; AIDS Unit, Westminster Hospital, London, U.K.; A series of 83 rectal biopsies was examined by electron microscopy (EM), 78 from HIV-seropositive patients (64 with diarrhoea, 9 with weight loss, and 5 asymptomatic) and 5 from controls without risk factors for HIV infection. Although EM identified the likely cause of the diarrhoea in only nine cases, the majority of
In situ characterization of gingival mononuclear cells in rapidly progressive periodontitis.: J Periodontol. 1993 Feb;64(2):120-7. Unique Identifier : AIDSLINE MED/93164036; Celenligil H; Kansu E; Ruacan S; Eratalay K; Caglayan G; Hacettepe University, Faculty of Dentistry, Department of; Periodontology, Ankara, Turkey.; Rapidly progressive periodontitis (RPP) has been suggested as a distinct clinical entity within the spectrum of early onset periodontitis. Immunological mechanisms have been considered in the pathogenesis of RPP. This study was designed to evaluate the distribution and phenotypic properties of the lymphocyte populatio
Simian immunodeficiency virus infection via amniotic fluid: a model to study fetal immunopathogenesis and prophylaxis.: J Acquir Immune Defic Syndr. 1993 Feb;6(2):107-14. Unique Identifier : AIDSLINE MED/93164099; Fazely F; Sharma PL; Fratazzi C; Greene MF; Wyand MS; Memon MA; Penninck D; Ruprecht RM; Laboratory of Viral Pathogenesis, Dana-Farber Cancer Institute,; Boston, MA 02115.; The rising prevalence of infection with the human immunodeficiency virus type 1 (HIV-1) in young women will increase the number of infected children worldwide. Because HIV-1 seems to be transmitted mostly intrapartum, fetal infection probably occurs mainly via skin or mucous membrane exposure. A model for this route o
Comparative evaluation of six rapid serological tests for HIV-1 antibody [see comments]: J Acquir Immune Defic Syndr. 1993 Feb;6(2):115-9. Unique Identifier : AIDSLINE MED/93164100; Malone JD; Smith ES; Sheffield J; Bigelow D; Hyams KC; Beardsley SG; Lewis RS; Roberts CR; Infectious Disease Division, National Naval Medical Center,; Bethesda, MD 50014-5000.; Six commercial rapid test kits for HIV-1 antibody were evaluated. Four laboratory technologists tested sera from four groups of U.S. military personnel or dependents: 202 subjects positive for HIV-1 antibody by Western blot, 200 seronegative voluntary blood donors, 199 seronegative obstetrics/gynecology patients, and
Effect of zidovudine on human placental trophoblast and Hofbauer cell functions.: J Acquir Immune Defic Syndr. 1993 Feb;6(2):120-6. Unique Identifier : AIDSLINE MED/93164101; Bui T; Bark D; Perkins M; Vu H; Unadkat JD; Ho RJ; Department of Pharmaceutics, University of Washington School of; Pharmacy, Seattle.; We have optimized a procedure to isolate placental trophoblasts and Hofbauer cells simultaneously in a quantity sufficient for short-term cultures and then used these placental cells to investigate the effects of zidovudine (ZDV) on trophoblast and Hofbauer cell functions. Of more than 10 term placentas tested, ZDV in
T cell homeostasis in HIV infection: part of the solution, or part of the problem? [editorial; comment] [see comments]: J Acquir Immune Defic Syndr. 1993 Feb;6(2):142-3. Unique Identifier : AIDSLINE MED/93164104; Stanley SK; Fauci AS
HIV protease inhibitors: their anti-HIV activity and potential role in treatment.: J Acquir Immune Defic Syndr. 1993 Feb;6(2):162-70. Unique Identifier : AIDSLINE MED/93164107; Robins T; Plattner J; Pharmaceutical Products Division, Abbott Laboratories, Abbott; Park, Illinois.; Researchers are continuing to uncover important new information about the life cycle of the human immunodeficiency virus (HIV) and are further elucidating the products of the viral genome in their efforts to develop anti-retroviral therapies that are more effective and safer than those currently available. Although mu
Detection of HIV-1 provirus in bronchoalveolar lavage cells by polymerase chain reaction.: J Acquir Immune Defic Syndr. 1993 Feb;6(2):171-5. Unique Identifier : AIDSLINE MED/93164108; Landay AL; Schade SZ; Takefman DM; Kuhns MC; McNamara AL; Rosen RL; Kessler HA; Spear GT; Department of Immunology/Microbiology, Rush-Presbyterian-St.; Luke's Medical Center, Chicago, IL 60612.; This study was undertaken to evaluate whether HIV-seropositive individuals harbor HIV provirus in cells obtained by bronchoalveolar lavage (BAL). BAL cells were obtained from 14 HIV-positive patients undergoing bronchoscopy for evaluation of acute pulmonary symptoms. Cells were fractionated into macrophage-enriched an
Decision making for clinical trials and prevention research: commentary on the model of Paltiel and Kaplan [editorial; comment]: J Acquir Immune Defic Syndr. 1993 Feb;6(2):176-8. Unique Identifier : AIDSLINE MED/93164109; Vermund SH
The epidemiological and economic consequences of AIDS clinical trials [see comments]: J Acquir Immune Defic Syndr. 1993 Feb;6(2):179-90. Unique Identifier : AIDSLINE MED/93164110; Paltiel AD; Kaplan EH; Department of Health Policy and Management, Harvard School of; Public Health, Boston, Massachusetts 02115.; The Food and Drug Administration ( FDA ) must manage the delicate balance between speed and safety in the evaluation and approval of new drugs. To explore how these competing obligations might be formalized with respect to the AIDS epidemic, we present a simple decision-theoretic optimi
Seasonal migration: a risk factor for HIV infection in rural Senegal.: J Acquir Immune Defic Syndr. 1993 Feb;6(2):196-200. Unique Identifier : AIDSLINE MED/93164112; Pison G; Le Guenno B; Lagarde E; Enel C; Seck C; Laboratoire d'Anthropologie Biologique (UA 49 CNRS), Museum; National d'Histoire Naturelle, Paris, France.; Sociodemographic and epidemiological data collected on a rural population of the Ziguinchor region of Senegal showed that a large part of the adult population, 80% of women between 15 and 24 years old and 82% of men between 20 and 40 years old, move each year on seasonal labor mig
Antibody avidity measurement and immune complex dissociation for serological diagnosis of vertically acquired HIV-1 infection.: J Acquir Immune Defic Syndr. 1993 Feb;6(2):201-7. Unique Identifier : AIDSLINE MED/93164113; Simon F; Rahimy C; Krivine A; Levine M; Pepin JM; Lapierre D; Denamur E; Vernoux L; De Crepy A; Blot P; et al; Laboratoire de Virologie, Hopital Bichat-Cl. Bernard, Paris,; France.; Differences in avidity between HIV-1 antibodies transmitted passively and antibodies synthesized by children born to HIV-1-positive mothers can be measured using a commercially available competitive enzyme immunoassay kit. The avidity determination method is based on the competition between an anti-HIV-1-peroxidase-la
Epidemiology of HIV infection in St. Petersburg, Russia.: J Acquir Immune Defic Syndr. 1993 Feb;6(2):208-12. Unique Identifier : AIDSLINE MED/93164114; Kozlov AP; Volkova GV; Malykh AG; Stepanova GS; Glebov AV; Bruce Rappaport Biomedical Center, St. Petersburg, Russia.; Overall HIV-1 prevalence in St. Petersburg (Leningrad) is extremely low (0.002%). HIV-2 infection has not been detected. The possible mode of virus entry was through sexual contacts with infected foreigners, the earliest documented date being prior to 1982. Among 25 seropositive males, 18 are homosexual and five are b
HTLV-I-associated neurologic manifestations in four generations of a Brazilian family.: J Acquir Immune Defic Syndr. 1993 Feb;6(2):213-7. Unique Identifier : AIDSLINE MED/93164115; Cavalcanti M; Ferreira Junior O; Puccioni M; Novis S; Schechter M; Department of Preventive Medicine, Federal University of Rio de; Janeiro, Brazil.; From an index case of tropical spastic paraparesis (TSP), four generations of a Brazilian family of African descent were investigated for human T-lymphotropic virus type I (HTLV-I) infection and its association with neurologic manifestations, as well as the possible routes of transmission. Thirty-two individuals were
Inactivation of human immunodeficiency virus-1 at short time intervals using undiluted bleach [letter] [see comments]: J Acquir Immune Defic Syndr. 1993 Feb;6(2):218-9. Unique Identifier : AIDSLINE MED/93164116; Shapshak P; McCoy CB; Rivers JE; Chitwood DD; Mash DC; Weatherby NL; Inciardi JA; Shah SM; Brown BS
Magnetic resonance spectroscopy may offer early look at HIV disease-mediated changes in brain [news]: JAMA. 1993 Mar 3;269(9):1084. Unique Identifier : AIDSLINE MED/93164343; Skolnick AA
Obtaining drug for AIDS-related toxoplasmosis [news]: JAMA. 1993 Mar 3;269(9):1086. Unique Identifier : AIDSLINE MED/93164344; Skolnick AA
From the Centers for Disease Control and Prevention. Differences between anonymous and confidential registrants for HIV testing--Seattle, 1986-1992.: JAMA. 1993 Mar 3;269(9):1094, 1096. Unique Identifier : AIDSLINE MED/93164350
Mandatory testing for HIV [letter; comment]: JAMA. 1993 Mar 3;269(9):1115. Unique Identifier : AIDSLINE MED/93164361; Harris CJ
Mandatory testing for HIV [letter; comment]: JAMA. 1993 Mar 3;269(9):1115-6. Unique Identifier : AIDSLINE MED/93164362; Morens DM
Mandatory testing for HIV [letter; comment]: JAMA. 1993 Mar 3;269(9):1116. Unique Identifier : AIDSLINE MED/93164363; Sargent E
Preventive health care for adults with HIV infection [see comments]: JAMA. 1993 Mar 3;269(9):1144-53. Unique Identifier : AIDSLINE MED/93164370; Jewett JF; Hecht FM; Department of Medicine, Brigham and Women's Hospital, Boston,; Mass.; OBJECTIVE--To assess the level of evidence for preventive health interventions for adults with human immunodeficiency virus (HIV) infection. DATA SOURCES--A MEDLINE literature search for each intervention, supplemented by reviewing conference proceedings and the recommendations of experts. STUDY SELECTION--English-lan
Factors associated with patient satisfaction among symptomatic HIV-infected persons.: Med Care. 1993 Feb;31(2):182-8. Unique Identifier : AIDSLINE MED/93164707; Stein MD; Fleishman J; Mor V; Dresser M; Brown University School of Medicine, Providence, RI.
[Loss of potential life years through AIDS in Spain 1981-1990 (see comments)]: Med Clin (Barc). 1993 Feb 20;100(7):245-8. Unique Identifier : AIDSLINE MED/93164711; Castilla Catalan J; Inigo Martinez J; Sendra Gutierrez JM; Tello Anchuela O; Centro Nacional de Epidemiologia, Instituto de Salud Carlos III,; Madrid.; BACKGROUND: To know the importance of AIDS in premature mortality in Spain in relation to the remaining causes of deaths. METHODS: Deaths of patients with AIDS were obtained from the National AIDS Registry and deaths from other causes from the official mortality statistics. The pote
Ewing's sarcoma in a child with human immunodeficiency virus (type 1) infection.: Med Pediatr Oncol. 1993;21(2):127-31. Unique Identifier : AIDSLINE MED/93164945; Lyall EG; Langdale-Brown B; Eden OB; Mok JY; Croft NM; Department of Haematology, Royal Hospital for Sick Children,; Edinburgh, Scotland.; A male child with vertically transmitted human immunodeficiency virus type 1 (HIV) infection developed a Ewing s sarcoma of the left fibula at 6.1 years of age. We report the antitumour chemotherapy given and the response of the tumour. Six months after tumour diagnosis the child died of probable HIV encephalopathy. T
Deficits in AIDS/HIV knowledge among physicians and nurses at a Minnesota public teaching hospital.: Minn Med. 1993 Feb;76(2):23-7. Unique Identifier : AIDSLINE MED/93164973; Henry K; Sullivan C; Campbell S; Department of Medicine, St. Paul-Ramsey Medical Center.; We administered a questionnaire pertaining to recent gains in knowledge about HIV/AIDS treatment and natural history in mid-1990 to all physicians and nurses at a 455-bed public teaching hospital. Surveys were returned by 127 physicians (46%) and 541 nurses (77%). Responses indicated that only 37% of physicians and 18
Live virus shows promise as AIDS vaccine [news]: Minn Med. 1993 Feb;76(2):52. Unique Identifier : AIDSLINE MED/93164980
Monoclonal antibodies to HIV-1 p24 core protein include pairs which exhibit synergistic binding.: Mol Immunol. 1993 Feb;30(3):243-54. Unique Identifier : AIDSLINE GENBANK/M91701; Stevens PW; Francis CH; Jolley ME; Bethell DR; Baxter Diagnostics Inc., Pandex Division, Mundelein, IL 60060.; Gamma and kappa chain cDNAs from four mouse monoclonal antibodies (mAbs) which bind three different sites on the core antigen (p24) of HIV-1 have been cloned and their V-region sequences determined. These mAbs are part of a larger group of seven anti-p24 mAbs analyzed in simultaneous competition assays with HIV-1 lysa
High molecular weight non-immunoglobulin salivary agglutinins (NIA) bind C1Q globular heads and have the potential to activate the first complement component.: Mol Immunol. 1993 Feb;30(3):309-19. Unique Identifier : AIDSLINE MED/93165050; Boackle RJ; Connor MH; Vesely J; Department of Stomatology, Medical University of South Carolina,; Charleston 29425-2230.; Non-Immunoglobulin Salivary Agglutinins (NIA) which directly bind to microbes [including HIV] were studied for their potential to activate the first complement component (C1). It was determined that NIA had the same specific activity as heat aggregated IgG in binding to C1q and in activating C1. In order to determine
Brief report: trimethoprim-induced hyperkalemia in a patient with AIDS.: N Engl J Med. 1993 Mar 11;328(10):703-6. Unique Identifier : AIDSLINE MED/93165093; Choi MJ; Fernandez PC; Patnaik A; Coupaye-Gerard B; D'Andrea D; Szerlip H; Kleyman TR; Philadelphia Veterans Affairs Medical Center, PA 19104.
The risks of HIV infection [letter; comment]: N C Med J. 1993 Feb;54(2):56. Unique Identifier : AIDSLINE MED/93165114; Dykers JR Jr
Evolution of sequence divergence among human immunodeficiency virus type 1 isolates derived from a blood donor and a recipient.: Pediatr Res. 1993 Jan;33(1):36-42. Unique Identifier : AIDSLINE MED/93165379; McNearney T; Hornickova Z; Kloster B; Birdwell A; Storch GA; Polmar SH; Arens M; Ratner L; Department of Medicine, Washington University School of Medicine,; St. Louis, Missouri 63110.; Four neonates who were infected with a single unit of blood from a human immunodeficiency virus-1 (HIV-1)-infected adult (patient 1) were studied. Two of the infected children (patients II and III) developed symptomatic HIV-1 disease and died within the first 3 y of life. One child (patient IV) died at 8 mo of age of
Features of human immunodeficiency virus infection and disease.: Pediatr Res. 1993 Jan;33(1 Suppl):S63-9; discussion S69-70. Unique Identifier : AIDSLINE MED/93165402; Levy JA; Department of Medicine, University of California School of; Medicine, San Francisco 94143-0128.; Characteristics of human immunodeficiency virus (HIV) strains and the host immune response against the virus are major determinants in the pathogenesis of AIDS. HIV isolates can be distinguished by their ability to infect and replicate to high titers in cells, to kill those cells, and to down-modulate the CD4 protein
Abnormalities of immune regulation in human immunodeficiency virus infection.: Pediatr Res. 1993 Jan;33(1 Suppl):S71-4; discussion S74-5. Unique Identifier : AIDSLINE MED/93165403; Shearer GM; Clerici M; Experimental Immunology Branch, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.; The severe depletion of CD4+ T cells is the most obvious and dramatic immunologic event that occurs in individuals infected with the human immunodeficiency virus (HIV) type 1 during development to AIDS. Nevertheless, a complex and sequential pattern of loss of T-helper cell (TH) function can occur years before develop
Maternofetal transmission of human immunodeficiency virus-1: the role of antibodies to the V3 primary neutralizing domain.: Pediatr Res. 1993 Jan;33(1 Suppl):S76-8; discussion S78-9. Unique Identifier : AIDSLINE MED/93165404; Rubinstein A; Goldstein H; Calvelli T; Devash Y; Rubinstein R; Soeiro R; Lyman W; Department of Pediatrics, Albert Einstein College of Medicine,; Bronx, New York 10461.; The increase in the number of human immunodeficiency virus-1 (HIV-1)-infected children is a direct consequence of the heterosexual spread of the disease to women and the growing number of HIV-positive i.v. drug users. It is not known how the majority of infants born to HIV-1-infected women escape HIV-1 infection, and,
Intravenous immune globulin for the prevention of infections in children with symptomatic human immunodeficiency virus infection.: Pediatr Res. 1993 Jan;33(1 Suppl):S80-7; discussion S87-9. Unique Identifier : AIDSLINE MED/93165405; Mofenson LM; Moye J Jr; Pediatric, Adolescent and Maternal AIDS Branch, National; Institute of Child Health and Human Development, National; Institutes of Health, Bethesda, Maryland 20852.; Infection with human immunodeficiency virus (HIV) causes a progressive immunodeficiency, often manifested in adults by the development of infections with relatively rare, opportunistic organisms. However, in HIV-infected children, recurrent serious infections with common encapsulated bacteria, as well as recurrent min
Needle exchange project recommended for New Jersey.: N J Nurse. 1993 Jan-Feb;23(1):5. Unique Identifier : AIDSLINE MED/93165480; Wurmser T
AIDS and the gastrointestinal tract.: Postgrad Med. 1993 Feb;93(2):143-8, 151-2. Unique Identifier : AIDSLINE MED/93165548; Forsmark CE; University of Florida College of Medicine, Gainesville 32610.; Gastrointestinal disease in AIDS most often affects three major areas: the bowel, the esophagus, and the liver. Investigation should be tailored to identify treatable causes of disease, bearing in mind that multiple infections, superinfection, and untreatable diseases are common. Clinical decisions must be made regard
Combined use of an immunotoxin and cyclosporine to prevent both activated and quiescent peripheral blood T cells from producing type 1 human immunodeficiency virus.: Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1411-5. Unique Identifier : AIDSLINE MED/93165706; Bell KD; Ramilo O; Vitetta ES; Department of Microbiology, University of Texas Southwestern; Medical Center, Dallas 75235-9048.; Two different populations of infected T cells are present in human immunodeficiency virus (HIV)-infected individuals: activated cells that produce virions and quiescent cells that harbor the viral genome but are unable to produce virus unless they are activated. Using an in vitro model of acute HIV infection, we have
Electrostatic interactions modulate the RNA-binding and transactivation specificities of the human immunodeficiency virus and simian immunodeficiency virus Tat proteins.: Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1571-5. Unique Identifier : AIDSLINE MED/93165737; Tao J; Frankel AD; Whitehead Institute for Biomedical Research, Cambridge, MA 02142.; The transcriptional activating (Tat) proteins from human immunodeficiency virus and simian immunodeficiency virus are sequence-specific RNA-binding proteins. In human immunodeficiency virus Tat, a single arginine residue, flanked on each side by three to four basic amino acids, mediates specific binding to a bulge reg
A study of clients returning for counseling after HIV testing: implications for improving rates of return.: Public Health Rep. 1993 Jan-Feb;108(1):12-8. Unique Identifier : AIDSLINE MED/93165868; Valdiserri RO; Moore M; Gerber AR; Campbell CH Jr; Dillon BA; West GR; Centers for Disease Control and Prevention, Atlanta, GA 30333.; Pretest and posttest counseling have become standard components of prevention-oriented human immunodeficiency virus (HIV) antibody testing programs. However, not all persons who receive pretest counseling and testing return for posttest counseling. Records of 557,967 clients from January through December 1990, represe
Need for HIV education among public health personnel in Michigan.: Public Health Rep. 1993 Jan-Feb;108(1):127-31. Unique Identifier : AIDSLINE MED/93165870; Randall LM; Bryce JW; Bertler MJ; Pope RS; Lawrenchuk DW; HIV/AIDS Prevention and Intervention Section, Michigan Department; of Public Health, Lansing 48906.; Knowledge and attitudes related to human immunodeficiency virus (HIV) and the use of the universal precautions recommended by the Centers for Disease Control and Prevention were investigated among 807 State and 2,797 local public health personnel in Michigan in September 1989. Survey results indicated that the majorit
Illinois picks Dracula to symbolize AIDS threat to young people [letter]: Public Health Rep. 1993 Jan-Feb;108(1):143-4. Unique Identifier : AIDSLINE MED/93165873
States' responses to Title II of the Ryan White CARE Act.: Public Health Rep. 1993 Jan-Feb;108(1):4-11. Unique Identifier : AIDSLINE MED/93165877; McKinney MM; Wieland MK; Bowen GS; Goosby EP; Marconi KM; HRSA/BHRD, Rockville, MD 20857.; Title II of the Ryan White Comprehensive AIDS Resources Emergency (CARE) Act of 1990 provides formula-based grants to States to help them improve the quality, availability, and organization of health care and support services for people with human immunodeficiency virus (HIV) infection. This article reviews State expe
Heterosexual and mother-to-child transmission of AIDS in the hemophilia community.: Public Health Rep. 1993 Jan-Feb;108(1):99-105. Unique Identifier : AIDSLINE MED/93165886; Chorba TL; Holman RC; Evatt BL; Centers for Disease Control and Prevention (CDC), Atlanta, GA; 30333.; Growing awareness of the potential modes of transmission of the human immunodeficiency virus (HIV) has encouraged interest in the epidemiology of infection among sexual partners and children of HIV-infected persons. The authors reviewed data on two groups, the first being those with HIV infection acquired heterosexual
[The unbearable AIDS]: Rev Med Liege. 1993 Jan;48(1):31-42. Unique Identifier : AIDSLINE MED/93166113; Duyckaerts F
[Psychiatric care team, AIDS and the others...]: Rev Med Liege. 1993 Jan;48(1):42-7. Unique Identifier : AIDSLINE MED/93166114; Bertrand J; Departement de Medecine psychosomatique, Universite de Liege.
[From alarm to broken body. Chronicle of an HIV infection]: Rev Med Liege. 1993 Jan;48(1):47-53. Unique Identifier : AIDSLINE MED/93166115; Krings M; Defourny J; Luminet D; Sondag-Thull D; Centre de Reference SIDA, Universite de Liege.
[HIV transmission from mother to child (news)]: Schweiz Rundsch Med Prax. 1993 Feb 2;82(5):148. Unique Identifier : AIDSLINE MED/93166128
Impact of HIV-positive sera on the functional activity of polymorphonuclear neutrophils from healthy donors.: Scand J Immunol. 1993 Feb;37(2):159-64. Unique Identifier : AIDSLINE MED/93166204; Gabrilovich DI; Avdeeva LA; Serebrovskaya LV; Shepeleva GK; Suvorova ZK; Buravcova EV; Oganezov VK; Platonov AE; Habarova VV; Posly IM; et al; Laboratory of AIDS Epidemiology and Prevention, Central Institute; for Epidemiology, Moscow, Russia.; The impact of the sera from 64 HIV-1-infected patients on the functional activity of polymorphonuclear neutrophils (PMN) from 9 healthy donors was investigated. Augmentation of PMN oxygen radical production in the presence of sera from HIV-infected patients (PMN chemiluminescence) was demonstrated. This enhancement wa
Anthropology and AIDS: the cultural context of sexual risk behavior among urban Baganda women in Kampala, Uganda.: Soc Sci Med. 1993 Feb;36(4):429-39. Unique Identifier : AIDSLINE MED/93166300; McGrath JW; Rwabukwali CB; Schumann DA; Pearson-Marks J; Nakayiwa S; Namande B; Nakyobe L; Mukasa R; Department of Anthropology, Case Western Reserve University,; Cleveland, OH 44106.; One hundred and thirty Baganda women (65 HIV antibody positive and 65 HIV antibody negative), recruited from the Makerere University-Case Western Reserve University Collaborative Pediatric follow-up clinic in Kampala, Uganda were interviewed about cultural rules and norms for sexua
Recent trends in sex mortality ratios for adults in developed countries.: Soc Sci Med. 1993 Feb;36(4):451-62. Unique Identifier : AIDSLINE MED/93166302; Waldron I; Department of Biology, University of Pennsylvania, Philadelphia; 19104-6018.; This paper analyzes changes in sex mortality ratios between 1979 and 1987 for adults in 23 developed countries. (A sex mortality ratio is the ratio of male to female death rates.) Previous analyses have shown that during the mid-twentieth century sex mortality ratios increased for all adult age groups. During the 1980
Correlates of AIDS knowledge in samples of the general population.: Soc Sci Med. 1993 Feb;36(4):509-24. Unique Identifier : AIDSLINE MED/93166307; Peruga A; Celentano DD; HIV Research Unit, Pan American Health Organization, Washington,; DC 20037.; Eighty studies presenting original research are reviewed to explore the correlates of AIDS knowledge in samples of the general population. Results from these studies indicate that being highly educated, young or white increases the chances of being knowledgeable about AIDS and that a relationship exists between strong
Rhodococcus equi causing bacteremia in an adult with acute leukemia.: South Med J. 1993 Feb;86(2):244-6. Unique Identifier : AIDSLINE MED/93166339; Sladek GG; Frame JN; Department of Internal Medicine, National Naval Medical Center,; Bethesda, MD 20889-5600.; We have reported a case of isolated bacteremia due to Rhodococcus equi in an immunocompromised, non-HIV-infected patient with acute leukemia. This patient s illness demonstrates a rare presentation of an emerging opportunistic pathogen that may be potentially acquired via exposure to domestic horses or their habitat d
Prevalence of human immunodeficiency virus infection in a sample of immigrants in the United States.: West J Med. 1993 Feb;158(2):145-7. Unique Identifier : AIDSLINE MED/93166766; Studemeister AE; Kent GP; Department of Medicine, San Jose Medical Group, California.
Human immunodeficiency virus seroprevalence in primary care practices in the United States.: West J Med. 1993 Feb;158(2):148-52. Unique Identifier : AIDSLINE MED/93166767; Calonge BN; Petersen LR; Miller RS; Marshall G; Colorado Permanente Medical Group, PC, Denver.
[HTLV-I associated myelopathy with macular degeneration]: Nippon Ganka Gakkai Zasshi. 1993 Jan;97(1):135-40. Unique Identifier : AIDSLINE MED/93167095; Sekine N; Suzuki J; Takeda M; Igarashi Y; Nakagawa T; Watanabe T; Sato T; Wakai S; Tachi N; Department of Ophthamology, Sapporo Medical College, Japan.; The authors report a case of macular involvement in a patient with HTLV-I associated myelopathy (HAM). The patient was a 10-year-old girl who noticed sudden decreased vision in her right eye in November 1987. The corrected visual acuity was 0.01 in the right eye and 1.0 in the left eye. Fundus examination of the right
The spectrum of acquired immunodeficiency syndrome (AIDS)-associated malignancies in San Francisco, 1980-1987.: Am J Epidemiol. 1993 Jan 1;137(1):19-30. Unique Identifier : AIDSLINE MED/93167225; Reynolds P; Saunders LD; Layefsky ME; Lemp GF; California Department of Health Services, Environmental; Epidemiology Section, Emeryville 94608.; Population-based disease registries for acquired immunodeficiency syndrome (AIDS) and cancer were linked for San Francisco residents to study the pattern of AIDS-associated malignancies diagnosed during the time period 1980-1987. A total of 1,756 newly diagnosed malignancies were identified during these years among me
Prevalence of antibody to human T-cell lymphotropic virus type I in Okinawa, Japan, after an interval of 9 years.: Am J Epidemiol. 1993 Jan 1;137(1):43-8. Unique Identifier : AIDSLINE MED/93167227; Morofuji-Hirata M; Kajiyama W; Nakashima K; Noguchi A; Hayashi J; Kashiwagi S; Department of General Medicine, Kyushu University Hospital,; Fukuoka, Japan.; To clarify events related to age dependence of human T-cell lymphotropic virus type I (HTLV-I) seroprevalence, the authors carried out two seroepidemiologic studies at a 9-year interval on residents of Yonaguni Island, Okinawa, Japan . The overall prevalence was 17.8% (345/1,943) in
Kaposi's sarcoma of the head and neck in acquired immunodeficiency syndrome.: Am J Otolaryngol. 1993 Jan-Feb;14(1):5-14. Unique Identifier : AIDSLINE MED/93167446; Goldberg AN; Department of Otolaryngology, Washington University School of; Medicine, St Louis, MO.; Kaposi s sarcoma has emerged from obscurity to become a common treatment problem. Otolaryngologists can play a key role in diagnosis and treatment of the victims of AIDS given the frequency of involvement of the head and neck. Kaposi s sarcoma involvement of the head and neck is often the presenting symptom of AIDS, m
Quantitative polymerase chain reaction by monitoring enzymatic activity of DNA polymerase.: Anal Biochem. 1993 Jan;208(1):110-6. Unique Identifier : AIDSLINE MED/93167527; Yang B; Yolken R; Viscidi R; Eudowood Division of Infectious Diseases, Department of; Pediatrics, Johns Hopkins University School of Medicine,; Baltimore, Maryland 21205.; Nucleic acid amplification by polymerase chain reaction (PCR) is a very powerful technique in terms of sensitivity but is limited in terms of ability to perform accurate quantitation. While there is a theoretical correlation between copies of input target sequence and those of PCR product, the quantitative nature of t
Human immunodeficiency virus-infected macrophages, gp120, and N-methyl-D-aspartate receptor-mediated neurotoxicity [letter; comment]: Ann Neurol. 1993 Feb;33(2):227-8. Unique Identifier : AIDSLINE MED/93167774; Lipton SA
Quantitative in vitro assay for human immunodeficiency virus deoxyribonucleic acid integration.: Arch Biochem Biophys. 1993 Feb 1;300(2):756-60. Unique Identifier : AIDSLINE MED/93167867; Carteau S; Mouscadet JF; Goulaouic H; Subra F; Auclair C; Laboratoire de Pharmacologie Moleculaire, CNRS URA 147, INSERM U; 140, Institut Gustave Roussy, Villejuif, France.; An obligatory step of retroviral growth is the integration of a DNA copy of the viral RNA into the genomic DNA of the host. Recombinant human immunodeficiency virus type I (HIV-1) integrase (IN) expressed in Escherichia coli efficiently catalyzes the overall in vitro integration reaction, namely, the processing of the
Children of HIV positive haemophilic men.: Arch Dis Child. 1993 Jan;68(1):133-4. Unique Identifier : AIDSLINE MED/93167919; Goldman E; Lee C; Miller R; Kernoff P; Morris-Smith J; Taylor B; Royal Free Hospital and School of Medicine, London.; All 14 children who were conceived at the time their 12 haemophilic fathers were anti-HIV positive were shown to be HIV negative and to be healthy physically and mentally. Eleven of the 12 female partners have remained anti-HIV negative and one has seroconverted. Despite counselling it is likely that children will con
Futility in practice [see comments]: Arch Intern Med. 1993 Feb 22;153(4):437-41. Unique Identifier : AIDSLINE MED/93167974; Schneiderman LJ; Jecker N
Mycobacterium tuberculosis bacteremia in patients with and without human immunodeficiency virus infection.: Arch Intern Med. 1993 Feb 22;153(4):496-500. Unique Identifier : AIDSLINE MED/93167980; Bouza E; Diaz-Lopez MD; Moreno S; Bernaldo de Quiros JC; Vicente T; Berenguer J; Department of Clinical Microbiology, Hospital General Gregorio; Maranon, Madrid, Spain.; PURPOSE: To determine the incidence of Mycobacterium tuberculosis bacteremia in a general hospital and to describe the clinical characteristics, therapy, and outcome of patients with bacteremic tuberculosis. PATIENTS AND METHODS: Clinical charts of all patients in whom M tuberculosis was isolated from blood cultures d
In vitro activity of thalidomide against Mycobacterium avium complex [letter; comment]: Arch Intern Med. 1993 Feb 22;153(4):534. Unique Identifier : AIDSLINE MED/93167987; Vicente T; Ortega A; Munoz P; Diaz MD; Bouza E
Human T-cell leukemia virus type 1 protease protein expressed in Escherichia coli possesses aspartic proteinase activity.: Arch Virol. 1993;128(3-4):195-210. Unique Identifier : AIDSLINE GENBANK/X62990; Saiga A; Tanaka T; Orita S; Sato A; Sato S; Hachisu T; Abe K; Kimura Y; Kondo Y; Fujiwara T; et al; Shionogi Institute for Medical Science, Osaka, Japan.; We amplified the human T-cell leukemia virus type 1 (HTLV-1) protease gene fragment by polymerase chain reaction (PCR) and cloned it into a pUC plasmid vector. DNA sequencing data of the protease gene fragment indicated that it contained an open reading frame capable of encoding the active HTLV-1 protease. To express
Sequence analysis of selected regions of the env (V3 loop and gp41) and gag (p7) reading frames of Ethiopian human immunodeficiency virus type 1 strains.: Arch Virol. 1993;128(3-4):229-39. Unique Identifier : AIDSLINE MED/93168025; Ayehunie S; Johansson B; Sonnerborg A; Zewdie DW; Britton S; Strannegard O; Department of Biology, Addis Ababa University, Ethiopia.; Amplified polymerase chain reaction (PCR) products, corresponding to the V3 loop and gp41 of the env, and p7 of the gag region, from proviral DNA of several Ethiopian and Swedish HIV-1 strains were sequenced. Of the six amino acids (GPGRAF) that constitute the principal neutralizing determinant (PND) within the V3 loo
Comparison of the levels of inositol metabolites in transformed haemopoietic cells and their normal counterparts.: Biochem J. 1993 Feb 1;289 ( Pt 3):667-73. Unique Identifier : AIDSLINE MED/93168112; Bunce CM; French PJ; Allen P; Mountford JC; Moor B; Greaves MF; Michell RH; Brown G; Department of Immunology, University of Birmingham, Edgbaston,; U.K.; We have compared the levels of inositol metabolites in three pairs of normal and transformed cells which have been matched with respect to their cell lineage, differentiation and proliferation status: (i) normal human myeloid blast cells and the human promyelocytic leukaemic cell line, HL60; (ii) human umbilical-cord
Psychiatric nurses go mental.: Nurs Stand. 1993 Feb 10-16;7(21):54. Unique Identifier : AIDSLINE MED/93168598; Ryan T
The immune system as target for subclinical lead related toxicity.: Br J Ind Med. 1993 Feb;50(2):185-6. Unique Identifier : AIDSLINE MED/93168663; Fischbein A; Tsang P; Luo JC; Bekesi JG; Division of Environmental and Occupational Medicine, Mount Sinai; School of Medicine, City University of New York, NY 10029.
A new group on AIDS and tumors approved by the EORTC board [news]: Ann Oncol. 1993 Jan;4(1):2. Unique Identifier : AIDSLINE MED/93168671
Lung cancer in 19 patients with HIV infection. The Italian Cooperative Study Group on AIDS and Tumors (GICAT) [letter]: Ann Oncol. 1993 Jan;4(1):85-6. Unique Identifier : AIDSLINE MED/93168685; Vaccher E; Tirelli U; Spina M; Errante D; Crosato I; Sabbatani S; Sinicco A; Monfardini S
Ecology of the biting midge Leptoconops albiventris in French Polynesia. I. Biting cycle and influence of climatic factors.: Med Vet Entomol. 1993 Jan;7(1):73-9. Unique Identifier : AIDSLINE MED/93168954; Aussel JP; Unite d'Entomologie, ORSTOM-ITRMLM, Papeete, Tahiti, French; Polynesia.; The diurnal biting cycle of Leptoconops albiventris de Meijere (Diptera: Ceratopogonidae) is described from beaches of Nuku-Hiva, French Polynesia . Biting activity increased during the morning, diminished during the afternoon and wa
Evolving pattern of drug-induced toxic epidermal necrolysis.: Dermatology. 1993;186(1):32-7. Unique Identifier : AIDSLINE MED/93168999; Correia O; Chosidow O; Saiag P; Bastuji-Garin S; Revuz J; Roujeau JC; Department of Dermatology, Hopital Henri-Mondor, Universite; Paris-XII, Creteil, France.; A series of 90 consecutive cases of toxic epidermal necrolysis (TEN) observed in a single center between 1985 and March 1991 was compared to a previous series from the same institution in order to look for changes in the characteristics of the patients and in the drug etiology. The most salient change was the high pre
Dusting powder in surgeon's gloves. A historial review.: Br J Theatre Nurs. 1993 Jan;2(10):S6-10. Unique Identifier : AIDSLINE MED/93169029; Gutteridge P; The use of surgical gloves for any surgical procedure, or any event which may involve the spillage of body fluids, is now well known and even expected. In these days of HIV and other infectious diseases, protection for the patient is as important as protection for the carer and it is therefore vital that the gloves/pr
Theatres--the power and the gory?: Br J Theatre Nurs. 1993 Jan;2(10):15-7. Unique Identifier : AIDSLINE MED/93169032; Rogers G; It is over ten years since the Centres for Disease Control (CDC) in Atlanta Georgia became aware of the first cases of what has now been recognised as the global pandemic of AIDS. There have now been reports from over 170 countries and the World Health Organisation estimates that
Provision of a designated list for HIV services [letter]: Br J Theatre Nurs. 1993 Jan;2(10):20-1. Unique Identifier : AIDSLINE MED/93169034; Smith AJ
Universal precautions in the operating department.: Br J Theatre Nurs. 1993 Jan;2(10):4-7. Unique Identifier : AIDSLINE MED/93169037; Taylor M; Those operating theatre personnel who aim to keep up to date by reading the professional journals may well be confused and feel uninformed about the concept of universal precautions. While some authors focus on universal precautions, they do not mention operating theatres. Others continue to discuss the Human Immunode
[Epidemiologic and clinical aspects of HIV infection in homosexual patients and intravenous drug addicts in a comparative study]: Gesundheitswesen. 1993 Jan;55(1):28-32. Unique Identifier : AIDSLINE MED/93169068; Bunikowski R; Fitzek C; Trautmann M; Abteilung fur Innere Medizin mit Schwerpunkt; Infektionskrankheiten, Universitatsklinikum Rudolf Virchow,; Standort Charlottenburg.; The clinical course of HIV-infection was analysed in a group of homosexual patients (n = 76, 72%) compared to intravenous drug abusers (IVDA, n = 30, 28%) in a retrospective cross-sectional study. The mean age of homosexual patients was 37.5 years compared to 28 years for IVDA. The following diseases are found signifi
[Utilization of anonymous HIV testing by the federal health office--developments and motives]: Gesundheitswesen. 1993 Jan;55(1):33-7. Unique Identifier : AIDSLINE MED/93169069; Scheibner J; Waldvogel B; Staatliches Gesundheitsamt Ulm jetzt Gesundheitsamt Lubeck.; In the state-run health office in Ulm a survey of the frequency of anonymous HIV-antibody tests was taken between 1985 to 1991, of the age and gender representation from 1988 to 1991, of the test motives from 1.1.1990 to 1.3.1991. The result was a regressive trend following the test boom of 1987 and 1988, which is bec
Leading the community. Newfoundland's HIV scenario [news]: Can Fam Physician. 1993 Jan;39:176-8. Unique Identifier : AIDSLINE MED/93169106
Acute eosinophilic pneumonia induced by inhaled pentamidine isethionate.: BMJ. 1993 Jan 9;306(6870):109. Unique Identifier : AIDSLINE MED/93169179; Dupon M; Malou M; Rogues AM; Lacut JY; Hopital Pellegrin, Bordeaux, France.
Confounding in epidemiological studies [letter; comment]: BMJ. 1993 Jan 9;306(6870):142. Unique Identifier : AIDSLINE MED/93169202; Phillips AN; Davey Smith G
HIV prevalence: anonymous surveys yield more evidence [news]: BMJ. 1993 Jan 9;306(6870):87. Unique Identifier : AIDSLINE MED/93169231; Delamothe T
An algorithm for the identification of similar oligopeptides between amino acid sequences.: Comput Appl Biosci. 1993 Feb;9(1):93-100. Unique Identifier : AIDSLINE MED/93169505; Balzarotti V; Colizzi V; Morante S; Parisi V; Department of Physics, University of Rome Tor Vergata, Italy.; Molecular mimicry is the origin of common structural patterns in sequences of viral and host proteins, and it appears to be related to the development of autoimmune diseases. The identification of structural molecular similarities among viral and host proteins is thus very relevant in the development of engineered ant
Clinically unsuspected Hodgkin disease presenting initially in the bone marrow of patients infected with the human immunodeficiency virus.: Cancer. 1993 Feb 15;71(4):1235-8. Unique Identifier : AIDSLINE MED/93169569; Karcher DS; Division of Clinical Pathology, George Washington University; Medical Center, Washington, DC 20037.; BACKGROUND. Hodgkin disease (HD) in patients infected with the human immunodeficiency virus (HIV) is an aggressive neoplasm that often exhibits high stage and extranodal involvement at the time of presentation. Because of the propensity of HIV-associated HD to involve the bone marrow early in the course of the neoplas
[Clinical and pharmacologic review of antiviral agents]: Cas Lek Cesk. 1993 Jan 26;132(1):24-8. Unique Identifier : AIDSLINE MED/93169671; Vacek V; Klinika infekcnich nemoci 3, LF UK, Praha.; The author presents a review if pharmacokinetics, undesirable effects, drug interactions, dosage, indications and drug forms of antiviral chemotherapeutic agents used for systemic treatment: amantadine and rimantadine (influenza virus A), acyclovir (HSV-1, HSV-2 and VZV), gancic
Immunology of the vagina.: Clin Obstet Gynecol. 1993 Mar;36(1):122-8. Unique Identifier : AIDSLINE MED/93169838; Witkin SS; Department of Obstetrics and Gynecology, Cornell University; Medical College, New York, NY 10021.
Age differences in understanding of disease causality: AIDS, colds, and cancer.: Child Dev. 1993 Feb;64(1):272-84. Unique Identifier : AIDSLINE MED/93170020; Sigelman C; Maddock A; Epstein J; Carpenter W; Department of Psychology, George Washington University,; Washington, DC 20052.; The development of concepts of disease causality was explored by asking 9-, 11-, and 13-year-olds and college students about risk factors for AIDS, colds, and cancer. Their knowledge became more accurate and differentiated with age. Although younger children knew a good deal about what causes each of the diseases, the
Isolation and molecular characterization of a hyperglycemic neuropeptide from the sinus gland of the terrestrial isopod Armadillidium vulgare (Crustacea).: Eur J Biochem. 1993 Feb 1;211(3):601-7. Unique Identifier : AIDSLINE MED/93170291; Martin G; Sorokine O; Van Dorsselaer A; Laboratoire de biologie animale URA 1452, Universite de; Poitiers, France.; The major peptide from the sinus gland of the terrestrial isopod Armadillidium vulgare (Crustacea) has been extracted and purified by reverse-phase HPLC. This neuropeptide exhibited a high hyperglycemic activity and was therefore named A. vulgare crustacean hyperglycemic hormone (Arv-CHH). Its average molecular mass m
Limiting dilution analysis of interleukin-2-producing T cells responsive to recall and alloantigens in human immunodeficiency virus-infected and uninfected individuals.: Eur J Immunol. 1993 Feb;23(2):412-7. Unique Identifier : AIDSLINE MED/93170390; Schulick RD; Clerici M; Dolan MJ; Shearer GM; Experimental Immunology Branch, National Cancer Institute,; National Institutes of Health, Bethesda, MD 20892.; Peripheral blood mononuclear cells (PBMC) from individuals who were seropositive for the human immunodeficiency virus type 1 (HIV), and most without symptoms (HIV+) were compared with PBMC from healthy HIV-seronegative (HIV-) individuals for in vitro generated T helper cell (Th) responses. Th function in bulk culture
The trophoblast as an integral component of a macrophage-cytokine network.: Immunol Cell Biol. 1993 Feb;71 ( Pt 1):49-57. Unique Identifier : AIDSLINE MED/93170883; Guilbert L; Robertson SA; Wegmann TG; Department of Immunology, University of Alberta, Edmonton,; Canada.; The trophoblast, an epithelial cell of fetal origin that forms the physical barrier between the mother and developing conceptus, becomes a component of the host immune system during pregnancy. Of the classical immune cells, it most closely resembles the macrophage, also present in high numbers in the pregnant uterus.
Mother-to-child transmission of human T-lymphotropic virus type I (HTLV-I): an extended follow-up study on children between 18 and 22-24 years old in Okinawa, Japan.: Int J Cancer. 1993 Feb 20;53(4):597-600. Unique Identifier : AIDSLINE MED/93170934; Ueda K; Kusuhara K; Tokugawa K; Miyazaki C; Okada K; Maeda Y; Shiraki H; Fukada K; Department of Pediatrics, Faculty of Medicine, Kyushu University,; Fukuoka, Japan.; The significant difference observed between the seroprevalence of HTLV-I in adults and in children is as yet unexplained. To evaluate a hypothetical explanation of the existence of seroconversion cases of seronegative carriers for this phenomenon, 21 of 55 children who had been born to seropositive mothers and who rem
[Analysis of 1983-1991 Leipzig University Dermatology Clinic observed cases of syphilis]: Hautarzt. 1993 Jan;44(1):23-9. Unique Identifier : AIDSLINE MED/93171057; Haustein UF; Pfeil B; Zschiesche A; Klinik und Poliklinik fur Hautkrankheiten, Universitat Leipzig.; A total of 1380 patients with syphilis were diagnosed and treated from January 1983 to December 1991 at the Department of Dermatology and Venereology at Leipzig University in West Saxon, Federal Republic of Germany where the population is 1.4 million. The incidence of syphilis inc
Chronic hyperkeratotic herpes zoster and human immunodeficiency virus infection.: J Am Acad Dermatol. 1993 Feb;28(2 Pt 2):306-8. Unique Identifier : AIDSLINE MED/93171350; Grossman MC; Grossman ME; Department of Dermatology, College of Physicians and Surgeons,; New York, NY 10032.; A patient with human immunodeficiency virus infection had hyperkeratotic papules in the T 11 and T 12 dermatomes in which she previously had papulovesicular herpes zoster. Findings of a biopsy specimen and viral culture of these papules subsequently revealed varicella-zoster that eventually responded to prolonged high
Allergy and desensitization to zidovudine in patients with acquired immunodeficiency syndrome (AIDS).: J Allergy Clin Immunol. 1993 Feb;91(2):683-5. Unique Identifier : AIDSLINE MED/93171511; Carr A; Penny R; Cooper DA; Centre for Immunology, St. Vincent's Hospital, Sydney, Australia.
Mortality among injecting drug users: a critical reappraisal [see comments]: J Epidemiol Community Health. 1993 Feb;47(1):59-63. Unique Identifier : AIDSLINE MED/93171792; Frischer M; Bloor M; Goldberg D; Clark J; Green S; McKeganey N; Ruchill Hospital, Glasgow, United Kingdom.; STUDY OBJECTIVE--The aim was to quantify all cause mortality among injecting drug users. DESIGN--This was a retrospective analysis of 1989 data on injecting drug users and mortality obtained from three independent agencies: the Procurator Fiscal s Office, the General Register Office, and the Scottish HIV-test register
The concurrent maturation of mouse and human thymocytes in human fetal thymus implanted in NIH-beige-nude-xid mice is associated with the reconstitution of the murine immune system.: J Exp Med. 1993 Mar 1;177(3):821-32. Unique Identifier : AIDSLINE MED/93171822; Kollmann TR; Goldstein MM; Goldstein H; Department of Microbiology and Immunology, Albert Einstein; College of Medicine, Bronx, New York 10461.; To determine whether the human thymus provides an environment for the maturation of murine T cells, human fetal thymus and liver (hu-thy/liv) were implanted into congenitally athymic NIH-beige-nude-xid (BNX) mice or C.B-17 scid/scid (SCID) mice. 3 mo after implantation, in contrast to the hu-thy/liv implant in SCID mi
Noninfectious risks and new trends in transfusion practice.: J Fla Med Assoc. 1993 Jan;80(1):37-8. Unique Identifier : AIDSLINE MED/93171846; Walker RH; Department of Clinical Pathology, William Beaumont Hospital,; Royal Oak, Mich.; HIV infection and hepatitis are considered major transfusion risks, but there are other serious adverse effects; circulatory overload, acute hemolytic transfusion reaction, and graft-versus-host disease. Each can be minimized by attention to preventative measures. Current transfusion practice emphasizes the appropriat
MRI-pathological correlate of brain lesions in a necropsy case of HTLV-I associated myelopathy.: J Neurol Neurosurg Psychiatry. 1993 Feb;56(2):194-6. Unique Identifier : AIDSLINE MED/93171961; Ogata A; Nagashima K; Tashiro K; Miyakawa A; Mikuni C; Department of Neurology, Hokkaido University School of Medicine,; Sapporo, Japan.; A postmortem case of HTLV-I associated myelopathy (HAM)/tropical spastic paraparesis (TSP) with a history of remission and exacerbation of neurological signs and symptoms, resembling those of multiple sclerosis is reported. MRI analysis revealed lesions in the periventricular white matter in addition to atrophy of the
Home infusion of intravenous immune globulin in human immunodeficiency virus-infected children [see comments]: J Intraven Nurs. 1993 Jan-Feb;16(1):18-22. Unique Identifier : AIDSLINE MED/93172027; Poole JK; Intravenous immune globulin (IVIG) is administered prophylactically to reduce the development of secondary infections in human immunodeficiency virus (HIV)-infected children whose helper-inducer T-cell (CD4) lymphocyte count is greater than 200 cells/mm3. By progressively crippling the body s immune system, HIV allows
Home mental health care developed for AIDS patients [news]: J Psychosoc Nurs Ment Health Serv. 1993 Feb;31(2):43. Unique Identifier : AIDSLINE MED/93172185
Health of the nation: way forward in sexual health.: J R Soc Health. 1993 Feb;113(1):40-2. Unique Identifier : AIDSLINE MED/93172210; Thin RN; Department of Genitourinary Medicine (Sexually Transmitted; Diseases), St Thomas' Hospital, London.; Sexual health is a wide concept encompassing education, health promotion and disease prevention, diagnosis and management of sexually transmitted diseases, screening and counselling for HIV antibodies, management of HIV infected patients, family planning, termination of pregnancy, psychosexual counselling, prevention
Integration is essential for efficient gene expression of human immunodeficiency virus type 1.: J Virol. 1993 Mar;67(3):1169-74. Unique Identifier : AIDSLINE GENBANK/M19921; Sakai H; Kawamura M; Sakuragi J; Sakuragi S; Shibata R; Ishimoto A; Ono N; Ueda S; Adachi A; Institute for Virus Research, Kyoto University, Japan.; A mutant of human immunodeficiency virus type 1 which carries a frameshift insertion in the integrase/endonuclease region of pol gene was constructed in vitro. Upon transfection into cells, although this mutant exhibited a normal phenotype with respect to expression of gag, pol, and env genes and to generation of prog
Genetic heterogeneity in human T-cell leukemia/lymphoma virus type II.: J Virol. 1993 Mar;67(3):1175-84. Unique Identifier : AIDSLINE GENBANK/M99092; Dube DK; Sherman MP; Saksena NK; Bryz-Gornia V; Mendelson J; Love J; Arnold CB; Spicer T; Dube S; Glaser JB; et al; Department of Medicine, State University of New York Health; Science Center, Syracuse 13210.; DNA from the peripheral blood mononuclear cells of 17 different individuals infected with human T-cell lymphoma/leukemia virus type II (HTLV-II) was successfully amplified by the polymerase chain reaction (PCR) with the primer pair SK110/SK111. This primer pair is conserved among the pol genes of all primate T-cell ly
Proliferative response of Tax1-transduced primary human T cells to anti-CD3 antibody stimulation by an interleukin-2-independent pathway.: J Virol. 1993 Mar;67(3):1211-7. Unique Identifier : AIDSLINE MED/93172335; Akagi T; Shimotohno K; Virology Division, National Cancer Center Research Institute,; Tokyo, Japan.; The growth properties of human T-cell leukemia virus Tax1-transduced primary human T cells derived from peripheral blood lymphocytes were compared with those of the same subset of T cells transduced with a control vector. Tax1-transduced T cells exhibited slightly elevated responsiveness to externally added interleuki
Simian immunodeficiency viruses from central and western Africa: evidence for a new species-specific lentivirus in tantalus monkeys.: J Virol. 1993 Mar;67(3):1227-35. Unique Identifier : AIDSLINE GENBANK/M81076; Muller MC; Saksena NK; Nerrienet E; Chappey C; Herve VM; Durand JP; Legal-Campodonico P; Lang MC; Digoutte JP; Georges AJ; et al; Unite de Biologie des Retrovirus, Institut Pasteur, Paris,; France.; Although up to 50% of African green monkeys (AGMs) are infected by simian immunodeficiency viruses (SIV) in their natural habitat, they remain asymptomatic carriers of these lentiviruses. They provide an attractive model to study not only the origin but also the link among genetic variation, host-virus adaptation, and
Erythropoietin receptor (EpoR)-dependent mitogenicity of spleen focus-forming virus correlates with viral pathogenicity and processing of env protein but not with formation of gp52-EpoR complexes in the endoplasmic reticulum.: J Virol. 1993 Mar;67(3):1322-7. Unique Identifier : AIDSLINE MED/93172349; Wang Y; Kayman SC; Li JP; Pinter A; Laboratory of Retroviral Biology, Public Health Research; Institute, New York, New York.; Recent evidence suggests that interactions between spleen focus-forming virus (SFFV) env products and the erythropoietin receptor (EpoR) are responsible for viral pathogenicity. Infection of factor-dependent cell lines expressing epoR (the cloned gene for EpoR) with SFFVP is mitogenic, generating cell lines that are n
A subset of Pr65gag is nucleus associated in murine leukemia virus-infected cells.: J Virol. 1993 Mar;67(3):1350-6. Unique Identifier : AIDSLINE MED/93172353; Nash MA; Meyer MK; Decker GL; Arlinghaus RB; Department of Molecular Pathology, University of Texas M. D.; Anderson Cancer Center, Houston 77030.; Nuclei of cells infected with Moloney murine leukemia virus (MoMuLV) were examined for the presence of gag proteins. This analysis was performed in conjunction with other studies suggesting a possible role for gag proteins in regulating nuclear events relating to processing and/or transport of viral genomic RNA. We de
Two mechanisms of soluble CD4 (sCD4)-mediated inhibition of human immunodeficiency virus type 1 (HIV-1) infectivity and their relation to primary HIV-1 isolates with reduced sensitivity to sCD4.: J Virol. 1993 Mar;67(3):1461-71. Unique Identifier : AIDSLINE MED/93172365; Orloff SL; Kennedy MS; Belperron AA; Maddon PJ; McDougal JS; Immunology Branch, Centers for Disease Control, Atlanta, Georgia; 30333.; Two assays for measuring inhibition of human immunodeficiency virus type 1 (HIV-1) infection by soluble CD4 (sCD4) are described. Experiments in which sCD4, HIV-1, and cell concentrations and sequence of combination, noninfectious/infectious particle ratio, and temperature were varied produced results that support the
The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4.: J Virol. 1993 Mar;67(3):1511-6. Unique Identifier : AIDSLINE MED/93172370; Garcia JV; Alfano J; Miller AD; Department of Virology and Molecular Biology, St. Jude Children's; Research Hospital, Memphis, Tennessee 38105.; The nef gene product of human immunodeficiency virus type 1 has been shown to induce CD4 downregulation from the surface of human cells. To determine if this effect is species specific, we used a retroviral vector to transduce the human immunodeficiency virus type 1 nef gene into murine cells expressing human, chimpan
Autologous antibody response against the principal neutralizing domain of human immunodeficiency virus type 1 isolated from infected humans.: J Virol. 1993 Mar;67(3):1612-9. Unique Identifier : AIDSLINE +; Holmback K; Kusk P; Hulgaard EF; Bugge TH; Scheibel E; Lindhardt BO; Department of Virology, State Serum Institute, Copenhagen,; Denmark.; High titers of neutralizing antibodies in human immunodeficiency virus type 1 (HIV-1) infection are directed primarily against the third hypervariable domain (V3) of the virion envelope glycoprotein gp120. This region has been designated the principal neutralizing domain of HIV-1. Because the frequency and significanc
Calcium ions are required for cell fusion mediated by the CD4-human immunodeficiency virus type 1 envelope glycoprotein interaction.: J Virol. 1993 Mar;67(3):1647-52. Unique Identifier : AIDSLINE MED/93172385; Dimitrov DS; Broder CC; Berger EA; Blumenthal R; Section on Membrane Structure and Function, National Cancer; Institute, Bethesda, Maryland 20892.; Calcium ions are required for fusion of a wide variety of artificial and biological membranes. To examine the role of calcium ions for cell fusion mediated by interactions between CD4 and the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (gp120-gp41), we used two experimental systems: (i) cells exp
Replication of type 1 human immunodeficiency viruses containing linker substitution mutations in the -201 to -130 region of the long terminal repeat.: J Virol. 1993 Mar;67(3):1658-62. Unique Identifier : AIDSLINE MED/93172387; Kim JY; Gonzalez-Scarano F; Zeichner SL; Alwine JC; Department of Neurology, University of Pennsylvania Medical; Center, Philadelphia 19104-6146.; In previous transfection analyses using the chloramphenicol acetyltransferase reporter gene system, we determined that linker substitution (LS) mutations between -201 and -130 (relative to the transcription start site) of the human immunodeficiency virus type 1 long terminal repeat (LTR) caused moderate decreases in L
Cell-dependent requirement of human immunodeficiency virus type 1 Vif protein for maturation of virus particles.: J Virol. 1993 Mar;67(3):1663-6. Unique Identifier : AIDSLINE MED/93172388; Sakai H; Shibata R; Sakuragi J; Sakuragi S; Kawamura M; Adachi A; Institute for Virus Research, Kyoto University, Japan.; A highly sensitive single-round infection assay using a bacterial chloramphenicol acetyltransferase was developed to analyze an early stage of human immunodeficiency virus type 1 replication. By a combination of transfection and single-round infection assay, a virus with a vif mutation, depending on host cells from wh
Disulfide bond formation in the human immunodeficiency virus type 1 Nef protein.: J Virol. 1993 Mar;67(3):1676-80. Unique Identifier : AIDSLINE MED/93172391; Zazopoulos E; Haseltine WA; Division of Human Retrovirology, Dana-Farber Cancer Institute,; Boston, Massachusetts 02115.; Substitution of alanine for cysteine residues of the human immunodeficiency virus type 1 LAI (BRU) and ELI Nef proteins was used to determine pairing of the cysteine residues present in each protein. The results show that under nonreducing conditions, alternative pairing of the cysteines occurs. The preferred pairing
Simian immunodeficiency virus-specific CD8+ lymphocyte response in acutely infected rhesus monkeys.: J Virol. 1993 Mar;67(3):1707-11. Unique Identifier : AIDSLINE MED/93172397; Yasutomi Y; Reimann KA; Lord CI; Miller MD; Letvin NL; Harvard Medical School, New England Regional Primate Research; Center, Southborough, Massachusetts 01772-9102.; To assess the possible role of cytotoxic T lymphocytes (CTLs) in containing the spread of human immunodeficiency virus in acutely infected individuals, the temporal evolution of the virus-specific CD8+ lymphocyte response was defined in simian immunodeficiency virus of macaques (SIVmac)-infected rhesus monkeys. A brie
Replication and persistence of simian immunodeficiency virus variants after passage in macaque lymphocytes and established human cell lines.: J Virol. 1993 Mar;67(3):1727-33. Unique Identifier : AIDSLINE GENBANK/L04356; Rudensey LM; Papenhausen MD; Overbaugh J; Department of Microbiology, University of Washington, Seattle; 98195.; In lentivirus infections, there are typically few cells in the host that harbor the provirus. For this reason, molecular clones of human and simian immunodeficiency viruses (HIV and SIV) are generally derived after passage and amplification of the virus in cell culture. To determine whether SIV variants that persist i
Immunological aspects in patients with acute myocardial infarction.: Jpn Circ J. 1993 Jan;57(1):37-46. Unique Identifier : AIDSLINE MED/93172520; Kuroki S; Miyahara K; Uematsu T; Kagoshima Prefectural Hokusatsu Hospital.; In order to elucidate the immunological aspects of acute myocardial infarction (AMI), we studied lymphocyte subpopulations, immunoglobulin levels, and natural killer (NK) cell activity in 21 patients serially after admission within 24 h of AMI onset. The percent T cells, T cell count, and percent CD4-positive cells we
[AIDS and Mycobacterium avium complex infection]: Kekkaku. 1993 Jan;68(1):79-81. Unique Identifier : AIDSLINE MED/93172690; Toida I; Japan BCG Laboratory, Tokyo.; Infections with Mycobacterium avium complex (MAC) are the next most common complication in AIDS patients, and disseminated MAC infection is considered as an indicator disease of AIDS. Bacteriological and clinical features of MAC infection complicated with AIDS were reviewed. The number of AIDS patients in
[Therapy of severe AIDS-associated diarrhea with the somatostatin analog octreotide]: Med Klin. 1993 Jan 15;88(1):45-7. Unique Identifier : AIDSLINE MED/93172991; Oehler R; Loos U; Medizinische Klinik, Universitat Bonn.
Impact of new legislation on needle and syringe purchase and possession--Connecticut, 1992.: MMWR Morb Mortal Wkly Rep. 1993 Mar 5;42(8):145-8. Unique Identifier : AIDSLINE MED/93173030; Human immunodeficiency virus (HIV) and other bloodborne pathogens are transmitted among injecting-drug users (IDUs) through the reuse and sharing of contaminated needles and syringes (NSs). Of the 689 acquired immunodeficiency syndrome (AIDS) cases reported in Connecticut in 1992, 413 (60%) were associated with inject
Recommendations for HIV testing services for inpatients and outpatients in acute-care hospital settings.: MMWR Morb Mortal Wkly Rep. 1993 Mar 5;42(8):157-8. Unique Identifier : AIDSLINE MED/93173033
[Preoperative immunotherapy in patients with gastric cancer--with special reference to analysis with monoclonal antibodies of T-lymphocyte subsets and interleukin-2 oral administration of OK-432 (Picibanil)]: Nippon Geka Gakkai Zasshi. 1993 Jan;94(1):27-32. Unique Identifier : AIDSLINE MED/93173073; Izumi M; Second Department of Surgery, Gunma University School of; Medicine, Maebashi, Japan.; The effects of oral administration of OK-432 on immune reactivities of gut associated lymphoid tissue (GALT) were studied in patients with gastric cancer. The lymphocytes of peripheral blood, regional lymph nodes and spleen in patients with gastric cancer were measured by using different monoclonal antibodies and flow
Viral culture of HIV in neonates [letter; comment]: N Engl J Med. 1993 Mar 18;328(11):814; discussion 814-5. Unique Identifier : AIDSLINE MED/93173152; Krivine A; Lebon P
Viral culture of HIV in neonates [letter; comment]: N Engl J Med. 1993 Mar 18;328(11):814; discussion 814-5. Unique Identifier : AIDSLINE MED/93173153; Lyman WD; Soeiro R; Rubinstein A
Multiple cerebral hemorrhages in HTLV-I-associated myelopathy.: Neurology. 1993 Feb;43(2):412-4. Unique Identifier : AIDSLINE MED/93173321; Smith D; Lucas S; Jacewicz M; Department of Neurology and Neuroscience, New York; Hospital-Cornell University Medical Center, NY 10021.; We describe a 66-year-old woman with long-standing HTLV-I-associated myelopathy who developed multiple parenchymal hemorrhages and whose angiogram suggested cerebral vasculitis. After cyclophosphamide and glucocorticoid therapy, both her acute deficits and chronic paraparesis improved. HTLV-I may be an etiologic agent
AIDS and Chagas' disease.: Neurology. 1993 Feb;43(2):447-8. Unique Identifier : AIDSLINE MED/93173333; Metze K; Maciel JA Jr; Department of Pathology, Faculty of Medicine, State University of; Campinas, SP, Brazil.
Caring in the time of AIDS: the importance of empathy.: Nurs Adm Q. 1993 Winter;17(2):46-60. Unique Identifier : AIDSLINE MED/93173390; Bennett JA; DeMayo M; Saint Germain M
AIDS [news]: N Z Med J. 1993 Feb 24;106(950):69. Unique Identifier : AIDSLINE MED/93173412
Women with human immunodeficiency virus infection and abnormal Papanicolaou smears: a prospective study of colposcopy and clinical outcome.: Obstet Gynecol. 1993 Mar;81(3):372-7. Unique Identifier : AIDSLINE MED/93173427; Adachi A; Fleming I; Burk RD; Ho GY; Klein RS; Department of Obstetrics and Gynecology, Montefiore Medical; Center, Bronx, New York.; OBJECTIVE: To determine the effect of human immunodeficiency virus (HIV) infection on colposcopic and histologic findings and clinical outcome in women who have abnormal Papanicolaou smears. METHODS: We conducted a prospective study of women with abnormal Papanicolaou smears from among those participating in a longitu
New York AIDS policies authorized [news]: Occup Health Saf. 1993 Feb;62(2):12. Unique Identifier : AIDSLINE MED/93173454
Industry profile: healthcare hazards of the healthcare profession.: Occup Health Saf. 1993 Feb;62(2):54-7. Unique Identifier : AIDSLINE MED/93173456; Behling D; Guy J; Intensive Care Unit, Presbyterian St. Luke's Healthcare System,; Denver.
Radiographic imaging of sinusitis in HIV infection.: Otolaryngol Head Neck Surg. 1993 Jan;108(1):36-43. Unique Identifier : AIDSLINE MED/93173534; Armstrong M Jr; McArthur JC; Zinreich SJ; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins; University, Baltimore, MD.; Magnetic resonance images (MRI) of the brain from 75 homosexual men were reviewed to evaluate the frequency and severity of incidental sinus disease associated with human immunodeficiency virus (HIV). All scans had been performed for reasons other than a history of sinus disease. The opacification of each sinus cavity
Crab lice an indicator of other STDs [news]: Nurs Times. 1993 Feb 10-16;89(6):12. Unique Identifier : AIDSLINE MED/93173745
Sexual health--reaching out.: Nurs Times. 1993 Feb 17-23;89(7):34-6. Unique Identifier : AIDSLINE MED/93173773; Cameron S; Peacock W; Trotter G
Characterization of 17 human immunodeficiency virus-1 carrier cell lines with T cell, myelomonocyte, or megakaryocyte lineages.: Proc Soc Exp Biol Med. 1993 Mar;202(3):271-8. Unique Identifier : AIDSLINE MED/93173843; Matsuo Y; Kamiya T; Nakamura S; Yamamoto N; Uno F; Yoshida M; Nii S; Kurimoto M; Minowada J; Fujisaki Cell Center, Hayashibara Biochemical Laboratories, Inc.,; Okayama, Japan.; Of 29 hematopoietic cell lines tested for susceptibility to human immunodeficiency virus (HIV)-1HTLV-IIIB infection, all CD4+ cell lines became infected. Continuous culturing of infected cell lines resulted in nine HIV-1 carrier cell lines, including, for the first time, an HIV-1 carrier megakaryoblastic cell line, ME
The effects of an AIDS education program on the knowledge and attitudes of a physical therapy class.: Phys Ther. 1993 Mar;73(3):156-64. Unique Identifier : AIDSLINE MED/93173870; Held SL; Department of Physical Therapy, Daemen College, Amherst, NY; 14226.; BACKGROUND AND PURPOSE. The purpose of this investigation was to determine the effect of an education unit on physical therapy students knowledge about acquired immunodeficiency syndrome (AIDS), their attitudes toward patients with AIDS, and their willingness to treat patients who have AIDS. SUBJECTS. A sample of con
Mitochondrial myopathy associated with chronic zidovudine therapy in AIDS.: Q J Med. 1993 Jan;86(1):5-15. Unique Identifier : AIDSLINE MED/93173964; Peters BS; Winer J; Landon DN; Stotter A; Pinching AJ; Department of Immunology, St. Mary's Hospital, London.; One hundred and eighteen consecutively identified AIDS patients, 88 of whom received zidovudine (1000-1200 mg/day), were followed for 1 year to investigate prospectively the relationship between zidovudine and myopathy. Clinical and biochemical evidence of proximal myopathy was seen in 7 of 41 patients (17%) who had b
Superinfection in HIV diseases [letter]: Q J Med. 1993 Jan;86(1):69. Unique Identifier : AIDSLINE MED/93173966; Webster AD
Superinfection in HIV disease [letter]: Q J Med. 1993 Jan;86(1):69-70. Unique Identifier : AIDSLINE MED/93173967; Griffin GE
Detection and significance of HIV sequences in HIV infection.: Prog Med Virol. 1993;40:19-47. Unique Identifier : AIDSLINE MED/93174006; Lewis DE; Gibbs RA; Department of Microbiology and Immunology, Baylor College of; Medicine, Houston, Tex.
Pneumothorax in patients with AIDS [see comments]: Respir Med. 1993 Jan;87(1):43-7. Unique Identifier : AIDSLINE MED/93174056; Coker RJ; Moss F; Peters B; McCarty M; Nieman R; Claydon E; Mitchell D; Harris JR; Department of Genitourinary Medicine, St Mary's Hospital,; Paddington, London, U.K.; Eighty-seven inpatients were treated for 93 episodes of Pneumocystis carinii at St Mary s Hospital between January 1989 and December 1990. During this period, 298 patients with the acquired immunodeficiency syndrome (AIDS) were treated at this hospital. Sixteen episodes of pneumothorax occurred and 12 of these, occurr
[AIDS and tourism. What is essential for clinical practice]: Schweiz Rundsch Med Prax. 1993 Feb 16;82(7):189-92. Unique Identifier : AIDSLINE MED/93174116; Baltes R; Bosshard H; Bundesamt fur Gesundheitswesen (BAG), Bern.; The Swiss spend in the average 7% of their income for travelling and thus belong to the nation most eager to travel. Next to the technical preparation of a trip, medical prevention is equally important. Unfortunately, many physicians limit their activities around travelling to prescriptions for common troubles of trav
Don't overlook pain in AIDS patients.: RN. 1993 Feb;56(2):89. Unique Identifier : AIDSLINE MED/93174171; Scholz MJ
[Tuberculosis 1992: current clinical aspects, epidemiology and diagnosis]: Schweiz Med Wochenschr. 1993 Feb 6;123(5):140-7. Unique Identifier : AIDSLINE MED/93174227; Rochat T; Division de pneumologie, Hopital cantonal universitaire,; Geneve.; We review four different aspects of tuberculosis (TB), a disease which is making a comeback as a focus of medical attention. The diagnosis of TB in HIV infected individuals can be very challenging for the clinician and an increased number of side effects complicates treatment. Updated information in this area appears
[Indications for chemoprophylaxis of tuberculosis. Arguments for]: Schweiz Med Wochenschr. 1993 Feb 6;123(5):154-8. Unique Identifier : AIDSLINE MED/93174230; Nicod LP; Centre antituberculeux, Hopital cantonal universitaire de; Geneve.; After a first infection with M. tuberculosis, reactivation of the disease may be prevented by chemoprophylaxis with isoniazid or rifampicin. Such chemoprophylaxis should be administered to all subjects with an immune defect due to HIV infection, immunosuppressors, severe diabetes, renal insufficiency or silicosis. Ext
AIDS research. Shalala backs reorganization [news]: Science. 1993 Feb 12;259(5097):889. Unique Identifier : AIDSLINE MED/93174252; Cohen J
A 'Manhattan project' for AIDS? [news]: Science. 1993 Feb 19;259(5098):1112-4. Unique Identifier : AIDSLINE MED/93174272; Cohen J
Transfusion-associated transmission of human T-lymphotropic virus types I and II: experience of a regional blood center.: Transfusion. 1993 Mar;33(3):208-11. Unique Identifier : AIDSLINE MED/93174445; Herr V; Ambruso D; Fairfax M; Neumann A; Swanson P; Lee H; Belle Bonfils Memorial Blood Center, Denver, Colorado.; During a 22-month period, 78,000 blood donors were screened for human T-lymphotropic virus types I and II (HTLV-I/II) at Belle Bonfils Memorial Blood Center (Denver, Colorado). Positive donors and the living recipients of their previously donated blood components were evaluated for risk factors and symptoms related to
Rapamycin effects on immunologic reconstitution.: Transplant Proc. 1993 Feb;25(1 Pt 1):727-8. Unique Identifier : AIDSLINE MED/93174731; Vogelsang GB; Hess AD; Johns Hopkins Bone Marrow Transplant Unit, Baltimore, Maryland.
Eight-year actuarial graft and patient survival of kidney transplants in highly immunized recipients pretreated with total lymphoid irradiation: a single-center experience.: Transplant Proc. 1993 Feb;25(1 Pt 1):776-7. Unique Identifier : AIDSLINE MED/93174754; Molajoni ER; Bachetoni A; Cinti P; Poli L; Caricato M; Pretagostini R; Vetere A; Berloco P; Alfani D; Cortesini R; Divisione Trapianti d'Organo, Universita di Roma La Sapienza,; Rome, Italy.
Tuberculous abdominal sinuses and HIV diseases [letter]: Trop Doct. 1993 Jan;23(1):33-4. Unique Identifier : AIDSLINE MED/93174806; Desai G; Islam R
[Life expectancy of the drug addict]: Versicherungsmedizin. 1993 Feb 1;45(1):10-4. Unique Identifier : AIDSLINE MED/93174868; Staak M; Rupp CP; Institut fur Rechtsmedizin, Univ. zu Koln.; The exact characterization of the epidemiology of drug-related mortality demands investigations of cross-sectional dates and the pursuit of trends under scientifically correct conditions. At the moment the possibilities of research in this field are limited. This is the reason why conclusions concerning the life expec
Self-limiting infection by int/nef-double mutants of simian immunodeficiency virus.: Virology. 1993 Mar;193(1):115-23. Unique Identifier : AIDSLINE MED/93174919; Vogel M; Cichutek K; Norley S; Kurth R; Paul-Ehrlich-Institute, Langen, Germany.; Simian immunodeficiency virus (SIVmac) infectious for rhesus monkeys was altered by site-directed mutagenesis of genes influencing in vivo replication and persistence with the long-term goal to develop attenuated lentiviruses with limited replication capacity in vivo. Double mutants of SIVmac (termed delta-int 1 to 3)
Transcomplementation of VIF- HIV-1 mutants in CEM cells suggests that VIF affects late steps of the viral life cycle.: Virology. 1993 Mar;193(1):186-92. Unique Identifier : AIDSLINE MED/93174926; Blanc D; Patience C; Schulz TF; Weiss R; Spire B; Chester Beatty Laboratories, Institute of Cancer Research,; London, United Kingdom.; The vif gene of HIV-1 has previously been claimed to be essential for the ability of cell-free virus preparations to infect cells. Here we report that the CEM T-cell-line, stably transfected with and expressing vif, supports the replication of vif- HIV-1 viruses to the same extent as wild-type HIV1. Cell entry and ear
Intracellular transport and virion incorporation of vpx requires interaction with other virus type-specific components.: Virology. 1993 Mar;193(1):222-33. Unique Identifier : AIDSLINE MED/93174930; Kappes JC; Parkin JS; Conway JA; Kim J; Brouillette CG; Shaw GM; Hahn BH; Department of Medicine, University of Alabama, Birmingham 35294.; Viral protein X (vpx) is a virion-associated HIV-2/SIV accessory protein that enhances viral infectivity and replication in natural target cells. To investigate whether other viral components affect its biosynthesis, subcellular localization, and virion incorporation, we expressed HIV-2 vpx in a mammalian cell system
Morphogenic capabilities of human immunodeficiency virus type 1 gag and gag-pol proteins in insect cells.: Virology. 1993 Mar;193(1):242-55. Unique Identifier : AIDSLINE MED/93174932; Hughes BP; Booth TF; Belyaev AS; McIlroy D; Jowett J; Roy P; Laboratory of Molecular Biophysics, University of Oxford, United; Kingdom.; To determine the interaction between the gag precursor and the viral protease and to confirm the role of gag precursor in formation of human immunodeficiency virus type 1 particles, the gag and protease encoding regions of a proviral genome with mutations at the site between p17 and p24 or p24 and p15 were expressed b
In vitro differentiation of monocytoid THP-1 cells affects their permissiveness for HIV strains: a model system for studying the cellular basis of HIV differential tropism.: Virology. 1993 Mar;193(1):256-67. Unique Identifier : AIDSLINE MED/93174933; Meylan PR; Spina CA; Richman DD; Kornbluth RS; Department of Medicine, San Diego School of Medicine, University; of California.; The prototypic macrophage-tropic HIV-1 isolate, HIV-1BaL, cannot replicate in the monocytoid cell line THP-1. After induction of differentiation by a phorbol diester, a fraction of THP-1 cells became permissive to HIV-1BaL. In contrast, this treatment decreased permissiveness for the lymphotropic isolate HIV-1LAI. Vir
Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells.: Virology. 1993 Mar;193(1):303-12. Unique Identifier : AIDSLINE MED/93174939; Shirazi Y; Pitha PM; Oncology Center, Johns Hopkins University School of Medicine,; Baltimore, Maryland 21231.; Previously, we have shown that interferon (IFN)-alpha markedly inhibits human immunodeficiency virus type-1 (HIV-1) replication in the CEM-174 lymphocytic cell line during a single replication cycle. In the present study, we demonstrate that the IFN-mediated block of HIV-1 replication is at the level of HIV-1 provirus
Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function.: Virology. 1993 Mar;193(1):41-9. Unique Identifier : AIDSLINE MED/93174951; Hammes SR; Greene WC; Howard Hughes Medical Institute, Department of Medicine, Duke; University Medical Center, Durham, North Carolina 27710.; The Rex protein of the type I human T-cell leukemia virus (HTLV-I) is essential for viral replication, acting post-transcriptionally to enhance the expression of unspliced and singly spliced viral mRNAs that encode the Gag, Pol, and Env virion proteins. Rex function involves its direct interaction with a complex stem-
Induction of micronuclei by HTLV-I Tax: a cellular assay for function.: Virology. 1993 Mar;193(1):456-9. Unique Identifier : AIDSLINE MED/93174959; Majone F; Semmes OJ; Jeang KT; Laboratory of Molecular Microbiology, National Institute of; Allergy and Infectious Diseases, National Institutes of Health,; Bethesda, Maryland 20892.; Cellular chromosomal damage is ubiquitously seen in HTLV-I-transformed lymphocytes. It is also characteristic of cells that have been exposed to mutagens. A sensitive measurement for mutagen-induced DNA damage is the formation of micronuclei in treated cells. Because current evidence suggests that HTLV-I Tax is etiolo
The block to HIV-1 envelope glycoprotein-mediated membrane fusion in animal cells expressing human CD4 can be overcome by a human cell component(s).: Virology. 1993 Mar;193(1):483-91. Unique Identifier : AIDSLINE MED/93174965; Broder CC; Dimitrov DS; Blumenthal R; Berger EA; Laboratory of Viral Diseases, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda,; Maryland 20892.; Membrane fusion mediated by interaction of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein with the human CD4 molecule generally requires that the CD4 be expressed on a human cell. The failure of murine or simian cells expressing human CD4 to form syncytia upon mixing with cells expressing envelo
Secretion of a truncated form of the human immunodeficiency virus type 1 envelope glycoprotein.: Virology. 1993 Mar;193(1):510-4. Unique Identifier : AIDSLINE MED/93174971; Hallenberger S; Tucker SP; Owens RJ; Bernstein HB; Compans RW; Department of Microbiology, University of Alabama, Birmingham; 35294.; We have characterized a truncated secreted form of the HIV-1 envelope glycoprotein gene. Expression via a recombinant vaccinia virus resulted in a glycoprotein product of approximately 140 kDa (gp160t) and a minor cleavage product of 120 kDa (gp120). Pulse-chase analysis revealed that the majority of gp160t remained c
HIV infection of the BS-1 human stroma cell line: effect on murine hematopoiesis.: Virology. 1993 Mar;193(1):524-7. Unique Identifier : AIDSLINE MED/93174974; Steinberg HN; Anderson J; Crumpacker CS; Chatis PA; Hematology/Oncology Division, Harvard Thorndike Laboratory,; Charles A. Dana Research Institute, Boston, Massachusetts.; BS-1, a stroma cell line derived from normal human bone marrow, can support the growth of murine erythroid (BFU-E), granulocyte-macrophage (CFU-GM), and megakaryocyte (CFU-Meg) progenitor cells in a short-term in vitro coculture system. Exposure of BS-1 cell to the human immunodeficiency virus (HIV) prior to coculture
Autologous neutralizing antibodies prevail in HIV-2 but not in HIV-1 infection.: Virology. 1993 Mar;193(1):528-30. Unique Identifier : AIDSLINE MED/93174975; Bjorling E; Scarlatti G; von Gegerfelt A; Albert J; Biberfeld G; Chiodi F; Norrby E; Fenyo EM; Department of Virology, Karolinska Institute, Stockholm, Sweden.; Human immunodeficiency virus type 2 (HIV-2) has been reported to be less pathogenic than HIV-1. We have investigated the capacity of sera from nine HIV-2-infected individuals to neutralize their own autologous virus. All nine HIV-2-infected individuals neutralized autologous virus with titers ranging between 20 and 32
The endocrine complications of acquired immunodeficiency syndrome.: Adv Intern Med. 1993;38:323-36. Unique Identifier : AIDSLINE MED/93175231; Masharani U; Schambelan M; Department of Medicine, University of California, San Francisco; School of Medicine.
HIV telephone service for physicians [news]: Am Fam Physician. 1993 Mar;47(4):995. Unique Identifier : AIDSLINE MED/93175281
A steroid-responsive nephropathy in a child with human immunodeficiency virus infection [letter]: Am J Dis Child. 1993 Mar;147(3):261-2. Unique Identifier : AIDSLINE MED/93175408; Landor M; Bernstein L; Rubinstein A
Correlates of drug injection behaviors among methadone outpatients.: Am J Drug Alcohol Abuse. 1993;19(1):107-18. Unique Identifier : AIDSLINE MED/93175434; Kang SY; De Leon G; Narcotic and Drug Research, Inc., New York, New York 10013.; Intravenous drug use, which has been recognized as the second most common risk behavior associated with AIDS, was studied among methadone outpatients who were enrolled in a methadone program at a hospital-based clinic in New York City. Intercorrelations among the following variables were observed: sociodemographic, ps
Sexual versus psychiatric predictors of suicide in men with AIDS-related illnesses [letter; comment]: Am J Drug Alcohol Abuse. 1993;19(1):139-40. Unique Identifier : AIDSLINE MED/93175438; Lester D
Diffuse nodular regenerative hyperplasia of the liver associated with human immunodeficiency virus and visceral leishmaniasis.: Am J Gastroenterol. 1993 Mar;88(3):433-5. Unique Identifier : AIDSLINE MED/93175469; Fernandez-Miranda C; Colina F; Delgado JM; Lopez-Carreira M; Department of Internal Medicine and Pathology, Hospital; Universitario 12 de Octubre, Madrid, Spain.; We present a patient with human immunodeficiency virus (HIV) infection coincident with diffuse nodular regenerative hyperplasia (DNRH) of the liver and visceral leishmaniasis. This association has not been previously described. Some DNRH cases are secondary to irregular blood flow in the liver. In the presently descri
Pancreatitis in AIDS patients treated with didanosine [letter; comment]: Am J Gastroenterol. 1993 Mar;88(3):459-60. Unique Identifier : AIDSLINE MED/93175480; Daniels M
Fulminant hepatic failure in an AIDS patient: possible zidovudine-induced hepatotoxicity [letter]: Am J Gastroenterol. 1993 Mar;88(3):464-6. Unique Identifier : AIDSLINE MED/93175485; Shintaku M; Nasu K; Shimizu T
Hypoplastic anemia in an infant with human immunodeficiency virus (HIV) infection [letter]: Am J Hematol. 1993 Feb;42(2):236. Unique Identifier : AIDSLINE MED/93175517; Morad AB; Steuber CP; Mahoney DH; Hurwitz RL
A protocol for routine voluntary antepartum human immunodeficiency virus antibody screening.: Am J Obstet Gynecol. 1993 Feb;168(2):476-9. Unique Identifier : AIDSLINE MED/93175541; Lindsay MK; Department of Gynecology and Obstetrics, Emory University,; Atlanta, GA.; Human immunodeficiency virus infection among both women of reproductive age and their infants is rapidly increasing. One strategy to address this increase involves the offering of routine voluntary antepartum human immunodeficiency virus antibody counseling and testing. The rationale for this policy is that all prenat
The underrecognition of HIV infection in women in an inner-city emergency room.: Am J Public Health. 1993 Mar;83(3):363-8. Unique Identifier : AIDSLINE MED/93175607; Schoenbaum EE; Webber MP; Montefiore Medical Center/Albert Einstein College of Medicine,; Department of Epidemiology and Social Medicine, Bronx, New York; 10467.; OBJECTIVES. This study analyzed the recognition of human immunodeficiency virus (HIV) infection and associated factors in women and men attending an emergency room in the Bronx, New York, NY. METHODS. From April 16, 1989, to May 5, 1989, the emergency room records of 2102 consecutive patients 13 years of age or older
Underscoring the continued need for a sustained national HIV prevention and public education initiative [news]: Am J Public Health. 1993 Mar;83(3):455-6. Unique Identifier : AIDSLINE MED/93175624
Human sexual behavior research [news]: Am J Public Health. 1993 Mar;83(3):456-7. Unique Identifier : AIDSLINE MED/93175625
Occupational risks of infection in the surgical management of trauma patients.: Am J Surg. 1993 Feb;165(2A Suppl):26S-33S. Unique Identifier : AIDSLINE MED/93175633; Fry DE; Department of Surgery, University of New Mexico School of; Medicine, Albuquerque 87131.; The evolution of the acquired immunodeficiency syndrome secondary to the human immunodeficiency virus (HIV) has resulted in increased concern by surgeons and other members of the health care team with respect to occupationally acquired viral infections. Hepatitis B, hepatitis C, and other viral infections of the liver
ANA contemplates development of national policy statement on UAP.: Am Nurse. 1993 Feb;25(2):22. Unique Identifier : AIDSLINE MED/93175733; Eckles E
American Nurses Association publishes policies, documents on a variety of subjects related to AIDS/HIV [news]: AORN J. 1993 Mar;57(3):692-3, 696-7. Unique Identifier : AIDSLINE MED/93175846; Goldbaum C
Preventing glove tears, sharp injuries.: AORN J. 1993 Mar;57(3):703-6. Unique Identifier : AIDSLINE MED/93175848; Fox VJ
Pneumocystosis in patients with acquired immunodeficiency syndrome [letter; comment]: Crit Care Nurse. 1993 Feb;13(1):106-7. Unique Identifier : AIDSLINE MED/93145635; Cunningham JH
Heterosexual transmission of HIV [letter; comment]: JAMA. 1993 Feb 17;269(7):870. Unique Identifier : AIDSLINE MED/93148427; Rodrigues LC; Garcia Moreno C
More on disclosure of AIDS in celebrities [letter; comment]: N Engl J Med. 1993 Feb 25;328(8):583; discussion 584. Unique Identifier : AIDSLINE MED/93149231; Barat LM
Structural features of the trans-activation response RNA element of equine infectious anemia virus.: Biochemistry. 1993 Feb 2;32(4):1096-104. Unique Identifier : AIDSLINE MED/93144313; Hoffman DW; Colvin RA; Garcia-Blanco MA; White SW; Department of Microbiology, Duke University Medical Center,; Durham, North Carolina 27710.; A 25-nucleotide RNA with the sequence of the trans-activation response (TAR) element of equine infectious anemia virus (EIAV) was analyzed by biochemical methods and by one- and two-dimensional NMR spectroscopy. NMR, nuclease probing, and polyacrylamide gel migration rates show that the RNA consists of an A-helical st
Reduction of AIDS risk among 41 heroin addicted female street prostitutes: effects of free methadone maintenance.: J Addict Dis. 1993;12(1):7-23. Unique Identifier : AIDSLINE MED/93144361; Bellis DJ; Department of Public Administration, California State; University-San Bernardino 92407.; Interviews were previously conducted with 72 heroin-addicted female street prostitutes who spread HIV by sharing injection paraphernalia and engaging in unprotected sex with multiple male customers. Most were willing to enroll in free methadone maintenance if made available. Forty-one female addict-prostitutes subsequ
Tolerability of combined ganciclovir and didanosine for the treatment of cytomegalovirus disease associated with AIDS.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S69-73. Unique Identifier : AIDSLINE MED/93144555; Jacobson MA; Owen W; Campbell J; Brosgart C; Abrams DI; Department of Medicine, University of California, San Francisco.; Ganciclovir is one of only two drugs licensed by the U.S. Food and Drug Administration for the treatment of opportunistic cytomegalovirus ( CMV ) disease. The combination of ganciclovir and zidovudine has been reported to be po
Perinatal infections.: Curr Opin Obstet Gynecol. 1993 Feb;5(1):24-32. Unique Identifier : AIDSLINE MED/93144655; Lynch L; Ghidini A; Mount Sinai School of Medicine, New York, New York.; Information concerning the most recently discovered infections with perinatal implications is constantly expanding. Hepatitis C virus is responsible for the majority of cases of sporadic and transfusion-related non-A, non-B hepatitis. Its prevalence in the general obstetric population is approximately 2%, but it is mu
Tuberculosis--Part II (continuing education credit).: Calif Nurse. 1993 Jan;89(1):8-10. Unique Identifier : AIDSLINE MED/93145190; Hughes AM; Gillen M
Intralesional vinblastine for cutaneous Kaposi's sarcoma associated with acquired immunodeficiency syndrome. A clinical trial to evaluate efficacy and discomfort associated with infection.: J Am Acad Dermatol. 1993 Jan;28(1):61-5. Unique Identifier : AIDSLINE MED/93147310; Boudreaux AA; Smith LL; Cosby CD; Bason MM; Tappero JW; Berger TG; Department of Dermatology, University of California, San; Francisco.; BACKGROUND: Intralesional vinblastine has been used to treat Kaposi s sarcoma associated with acquired immunodeficiency syndrome (AIDS-KS). Injections are painful and anticipated response rates are not well documented. OBJECTIVE: Eleven homosexual men were studied to evaluate the efficacy and pain associated with intr
HIV-1-related neurological disease.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S10-5. Unique Identifier : AIDSLINE MED/93148105; Brew BJ; National Centre in HIV Epidemiology and Clinical Research, St.; Vincent's Medical Centre, Sydney, Australia.; Infection due to human immunodeficiency virus type 1 (HIV-1) frequently leads to neurological complications that may involve each part of the neuraxis. A brief discussion is presented of the nature of involvement, appropriate treatment modalities, and the diagnostic approach to such problems. Emphasis will be placed o
Roundtable discussion: management issues in didanosine therapy.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S51-5. Unique Identifier : AIDSLINE MED/93148114; Carr A; Penny R
Syntheses and biological evaluations of 3'-deoxy-3'-C-branched-chain-substituted nucleosides.: J Med Chem. 1993 Feb 5;36(3):353-62. Unique Identifier : AIDSLINE MED/93148297; Lin TS; Zhu JL; Dutschman GE; Cheng YC; Prusoff WH; Department of Pharmacology, Yale University School of Medicine,; New Haven, Connecticut 06510.; Various 3 -deoxy-3 -C-(hydroxymethyl)-, 3 -deoxy-3 -C-(fluoromethyl)-, 3 -deoxy-3 -C-(azidomethyl)-, and 3 -deoxy-3 -C-(aminomethyl)-substituted nucleosides (total 12 compounds) have been synthesized and evaluated against L1210, P388, S-180, and CCRF-CEM cells and HSV-1, HSV-2, and HIV-1 in culture. Only 3 -deoxy-3 -C
[HHV-6 in drug addicts and HIV (letter)]: Med Clin (Barc). 1993 Jan 23;100(3):115-6. Unique Identifier : AIDSLINE MED/93148704; Cuende Melero JI
[Observations on the classification of human immunodeficiency virus infection and associated diseases (letter)]: Med Clin (Barc). 1993 Jan 23;100(3):119. Unique Identifier : AIDSLINE MED/93148709; Teira R; Zubero Z
The emergence of drug-resistant tuberculosis in New York City [published erratum appears in N Engl J Med 1993 Jul 8;329(2):148] [see comments]: N Engl J Med. 1993 Feb 25;328(8):521-6. Unique Identifier : AIDSLINE MED/93149213; Frieden TR; Sterling T; Pablos-Mendez A; Kilburn JO; Cauthen GM; Dooley SW; Division of Field Epidemiology, Centers for Disease Control and; Prevention, Atlanta.; BACKGROUND. In the past decade the incidence of tuberculosis has increased nationwide and more than doubled in New York City, where there have been recent nosocomial outbreaks of multidrug-resistant tuberculosis. METHODS. We collected information on every patient in New York City with a positive culture for Mycobacter
Genital human papillomavirus infections: correlation of cytological, colposcopic and histological features with viral types in women and their male partners.: Int J STD AIDS. 1993 Jan-Feb;4(1):13-20. Unique Identifier : AIDSLINE MED/93152631; Monsonego J; Zerat L; Catalan F; Coscas Y; Departement de Depistage Cytocolposcopique, Institut Alfred; Fournier, Paris, France.; To determine the incidence of anogenital papillomavirus infections and to assess the value of available diagnostic methods, we compared the cytological, colposcopic and histological features of anogenital papillomavirus-related lesions with their associated human papillomavirus types (HPV) in 300 women and in their ma
Successful treatment of cutaneous cytomegalovirus.: Int J STD AIDS. 1993 Jan-Feb;4(1):52-3. Unique Identifier : AIDSLINE MED/93152639; Charthaigh MN; Crowley B; Lynch M; Mulcahy F; Department of Genitourinary Medicine, St James's Hospital,; Dublin, Ireland.
Search for intrafamilial transmission of hepatitis C virus in hemophilia patients.: Blood. 1993 Feb 15;81(4):1077-82. Unique Identifier : AIDSLINE MED/93152878; Brackmann SA; Gerritzen A; Oldenburg J; Brackmann HH; Schneweis KE; Institute of Medical Microbiology and Immunology, University of; Bonn, Germany.; This study was performed to determine the risk of family members of anti-hepatitis C virus (HCV)-positive hemophilia patients (index patients) for infection with HCV compared with the risk of acquiring hepatitis B virus (HBV), human immunodeficiency virus (HIV), and hepatitis A virus (HAV) infection. All index patient
Stavudine made available under parallel track policy [news]: Clin Pharm. 1993 Jan;12(1):7. Unique Identifier : AIDSLINE MED/93153971
Langerhans' cell counts and cervical intraepithelial neoplasia in women with human immunodeficiency virus infection.: Gynecol Oncol. 1993 Feb;48(2):210-3. Unique Identifier : AIDSLINE MED/93154626; Spinillo A; Tenti P; Zappatore R; De Seta F; Silini E; Guaschino S; Department of Obstetrics and Gynecology, University of Pavia,; IRCCS Policlinico S. Matteo, Italy.; The mean counts of Langerhans cells were evaluated in cervical biopsies obtained from 30 patients with human immunodeficiency virus (HIV) infection and cervical intraepithelial neoplasia (CIN) and from 30 HIV-seronegative control patients. Each HIV-seronegative control was matched to a seropositive case with respect
Oral CMV lesions and the HIV infected. Early recognition can help prevent morbidity.: J Am Dent Assoc. 1993 Feb;124(2):99-105. Unique Identifier : AIDSLINE MED/93155432; Heinic GS; Greenspan D; Greenspan JS; Department of Stomatology, University of California, San; Francisco 94143-0512.; Although they are rare, oral ulcers caused by cytomegalovirus infection can occur in immunocompromised people, including those infected with HIV. Once recognized, however, oral CMV lesions can be successfully treated in most
[Cytomegalovirus disease in patients with acquired immunodeficiency syndrome. Report of 63 cases (see comments)]: Med Clin (Barc). 1993 Jan 16;100(2):41-5. Unique Identifier : AIDSLINE MED/93156376; Martinez Lacasa JT; Podzamczer D; Rufi G; Bolao F; Perez JL; Gudiol F; Servicio de Enfermedades infecciosas, Hospital de; Bellvitge-Princeps d'Espanya, L'Hospitalet de Llobregat,; Barcelona.; BACKGROUND: The aim of the present was to study the clinical and therapeutic characteristics of patients with the human immunodeficiency virus (HIV) with disease by the cytomegalovirus (DCMV) observed between 1984-1990. Some concrete aspects such as viremia by the cytomegalovirus (
Increased survival of a cohort of patients with acquired immunodeficiency syndrome and cytomegalovirus retinitis who received sodium phosphonoformate (foscarnet) [see comments]: Am J Med. 1993 Feb;94(2):175-80. Unique Identifier : AIDSLINE MED/93158634; Polis MA; deSmet MD; Baird BF; Mellow S; Falloon J; Davey RT Jr; Kovacs JA; Palestine AG; Nussenblatt RB; Masur H; et al; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda,; Maryland 20892.; PURPOSE: To evaluate the impact of foscarnet on the longevity of persons with human immunodeficiency virus, type 1 (HIV-1) infection and cytomegalovirus ( CMV ) retinitis. PATIENTS AND METHODS: A cohort of 24 patients with acqu
Pneumocystis carinii pneumonia during steroid taper in patients with primary brain tumors.: Am J Med. 1993 Feb;94(2):216-9. Unique Identifier : AIDSLINE MED/93158640; Slivka A; Wen PY; Shea WM; Loeffler JS; Department of Medicine, Brigham and Women's Hospital, Boston,; Massachusetts.; Pneumocystis carinii causes life-threatening pneumonitis (PCP) in immunocompromised individuals. In the non-AIDS (acquired immunodeficiency syndrome) population, PCP is frequently associated with corticosteroid therapy, and the rodent model uses corticosteroid-induced immunosuppression to provoke PCP. Although patient
An unusual mediastinal tumor in a patient with AIDS.: Am J Med. 1993 Feb;94(2):221-2. Unique Identifier : AIDSLINE MED/93158642; Rohlman VC; Canfield VA; Greenfield RA; University of Oklahoma Health Sciences Center, Oklahoma City.
Early detection of bovine leukemia virus in cattle by use of the polymerase chain reaction.: Am J Vet Res. 1993 Feb;54(2):205-9. Unique Identifier : AIDSLINE MED/93158949; Kelly EJ; Jackson MK; Marsolais G; Morrey JD; Callan RJ; Department of Animal, Dairy and Veterinary Sciences, College of; Agriculture, Utah State University, Logan 84322-5600.; A study was performed to determine whether experimentally induced bovine leukemia virus (BLV) infection in cattle could be detected earlier by use of polymerase chain reaction (PCR) amplification of genomic DNA extracted from leukocytes than by use of conventional agar-gel immunodiffusion (AGID). The PCR primers were
Generation of drug-resistant variants of human immunodeficiency virus type 1 by in vitro passage in increasing concentrations of 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.: Antimicrob Agents Chemother. 1993 Jan;37(1):130-3. Unique Identifier : AIDSLINE MED/93159132; Gao Q; Gu Z; Hiscott J; Dionne G; Wainberg MA; Lady Davis Institute-Jewish General Hospital, Montreal, Quebec,; Canada.; We selected in vitro human immunodeficiency virus type 1 variants that are resistant to each of 2 ,3 -dideoxycytidine ( ddC ) and the racemic mixture of 2 ,3 -dideoxy-3 -thiacytidine (BCH-189). The median effective concentrations of ddC and BCH-189 obta
Virucidal effects of glucose oxidase and peroxidase or their protein conjugates on human immunodeficiency virus type 1.: Antimicrob Agents Chemother. 1993 Jan;37(1):26-31. Unique Identifier : AIDSLINE MED/93159140; Yamaguchi Y; Semmel M; Stanislawski L; Strosberg AD; Stanislawski M; Laboratoire d'Immunologie, Groupe de Laboratoires de l'Institut; de Recherches Scientifiques sur le Cancer, Villejuif, France.; Glucose oxidase and peroxidase (lactoperoxidase or myeloperoxidase) are virucidal to human immunodeficiency virus type 1 (HIV-1) in the presence of sodium iodide, as assessed by the loss of viral replication in a syncytium-forming assay or by the inhibition of cytopathic effects on infected cells. In the presence of l
Antiretroviral activities of protease inhibitors against murine leukemia virus and simian immunodeficiency virus in tissue culture.: Antimicrob Agents Chemother. 1993 Jan;37(1):71-7. Unique Identifier : AIDSLINE MED/93159148; Black PL; Downs MB; Lewis MG; Ussery MA; Dreyer GB; Petteway SR Jr; Lambert DM; Southern Research Institute-Frederick Research Center, Maryland; 21701.; Rationally designed synthetic inhibitors of retroviral proteases inhibit the processing of viral polyproteins in cultures of human immunodeficiency virus type 1 (HIV-1)-infected T lymphocytes and, as a result, inhibit the infectivity of HIV-1 for such cultures. The ability of HIV-1
AIDS and HIV: the dilemma of the health care worker.: ANNA J. 1993 Feb;20(1):59-62, 102-3. Unique Identifier : AIDSLINE MED/93159181; Wicher CP; The possible transmission of the HIV virus in the work setting has created many concerns for U.S. health care workers today. There is much debate over the methods of transmission, the best techniques for prevention, and the employability of those infected. This article examines these pressing issues, including the leg
Peripheral nervous system involvement in a large cohort of human immunodeficiency virus-infected individuals [published erratum appears in Arch Neurol 1993 Apr;50(4):388]: Arch Neurol. 1993 Feb;50(2):167-71. Unique Identifier : AIDSLINE MED/93159350; Barohn RJ; Gronseth GS; LeForce BR; McVey AL; McGuire SA; Butzin CA; King RB; Department of Neurology, Wilford Hall US Air Force Medical; Center, Lackland Air Force Base, Tex.; OBJECTIVE. In individuals who were infected with the human immunodeficiency virus (HIV) we determined the prevalence of peripheral neuropathies (PNs) and explored the relationship between immunologic competence and nerve function. DESIGN. Cohort survey. SETTING. US Air Force medical center. PATIENTS. Population based.
Natural history of AIDS related sclerosing cholangitis: a study of 20 cases.: Gut. 1993 Jan;34(1):116-21. Unique Identifier : AIDSLINE MED/93162494; Forbes A; Blanshard C; Gazzard B; Westminster Hospital, London.; A case control study of AIDS related sclerosing cholangitis indicates that it has no overall influence on prognosis, but is responsible for a striking reversal of the usual inverse correlation of age and survival in HIV infection. Pain, the principal symptom, was controlled in surviving patients with analgesics alone.
AIDS drug approved [news]: J Am Osteopath Assoc. 1993 Feb;93(2):261. Unique Identifier : AIDSLINE MED/93162981
Detection of bovine leukemia virus RNA in serum using the polymerase chain reaction.: J Virol Methods. 1993 Jan;41(1):101-12. Unique Identifier : AIDSLINE MED/93163178; Poon H; Jimenez E; Jacobs RM; Song Z; Jefferson B; Connaught Product Development Centre, Connaught Laboratories; Limited, Willowdale, Ont., Canada.; A method was developed for detecting bovine leukemia virus (BLV) RNA in serum samples using a pair of primers from the BLV polymerase gene in the polymerase chain reaction (PCR). The PCR was able to detect 3800-7600 molecules of BLV RNA. At this level of sensitivity eleven pools of adult and one fetal bovine serum app
Prophylactic ZDV therapy prevents early viremia and lymphocyte decline but not primary infection in feline immunodeficiency virus-inoculated cats.: J Acquir Immune Defic Syndr. 1993 Feb;6(2):127-34. Unique Identifier : AIDSLINE MED/93164102; Hayes KA; Lafrado LJ; Erickson JG; Marr JM; Mathes LE; Department of Veterinary Pathobiology, Ohio State University,; Columbus 43210.; Prophylactic zidovudine (ZDV) therapy was evaluated in the feline immunodeficiency virus (FIV)-inoculated cat model for HIV-1 infection in humans. ZDV treatment (30 mg/kg/day via continuous subcutaneous infusion) was initiated 48 h prior to virus inoculation and continued for 28 days. Transient plasma antigenemia evid
Population-based estimates of antiretroviral therapy and anti-Pneumocystis prophylaxis in San Francisco: 1991.: J Acquir Immune Defic Syndr. 1993 Feb;6(2):191-5. Unique Identifier : AIDSLINE MED/93164111; Lang W; Osmond D; Page-Bodkin K; Moss A; Winkelstein W Jr; California Pacific Medical Center, San Francisco 94118.; Using data from the San Francisco Men s Health Study and the San Francisco General Hospital Cohort, we derived partially population-based estimates of human immunodeficiency virus (HIV) antiretroviral therapy and Pneumocystis carinii prophylaxis use in HIV-infected men in 1991. Zidovudine, didanosine, and dideoxycytid
Renal disease associated with HIV infection: a multicentric study of 60 patients from Paris hospitals.: Nephrol Dial Transplant. 1993;8(1):11-9. Unique Identifier : AIDSLINE MED/93165195; Nochy D; Glotz D; Dosquet P; Pruna A; Guettier C; Weiss L; Hinglais N; Idatte JM; Mery JP; Kazatchkine M; et al; Unite INSERM U28, Hopital Broussais, Paris, France.; Sixty HIV-infected patients presenting renal symptoms who underwent percutaneous renal biopsies were analysed. According to the CDC classification, 44 patients were staged in group IV, five in group III, and 11 in group II. Patients were divided in two groups according to their ethnic origin (29 black patients and 31
Nurses' risks, rights, and responsibilities outlined.: Pa Nurse. 1993 Feb;48(2):6. Unique Identifier : AIDSLINE MED/93165324
Pathogenesis of immune-mediated neuropathies.: Pediatr Res. 1993 Jan;33(1 Suppl):S90-4. Unique Identifier : AIDSLINE MED/93165407; Rostami AM; Department of Neurology, University of Pennsylvania School of; Medicine, Philadelphia 19104.; A variety of peripheral neuropathies are believed to be immune-mediated. Acute inflammatory demyelinating polyneuropathy or Guillain-Barre syndrome (GBS) is the prototype of these neuropathies. GBS is characterized by acute progressive motor weakness of the extremities and of bulbar and facial musculature. Deep tendon
Human immunodeficiency virus coat protein gp120 inhibits the beta-adrenergic regulation of astroglial and microglial functions.: Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1541-5. Unique Identifier : AIDSLINE MED/93165731; Levi G; Patrizio M; Bernardo A; Petrucci TC; Agresti C; Laboratory of Pathophysiology, Istituto Superiore di Sanita,; Rome, Italy.; The goal of our study was to assess whether the human immunodeficiency virus (HIV) coat protein gp120 induces functional alterations in astrocytes and microglia, known for their reactivity and involvement in most types of brain pathology. We hypothesized that gp120-induced anomalies in glial functions, if present, mig
Cytologic diagnosis of cytomegaloviral esophagitis. A report of three acquired immunodeficiency syndrome-related cases.: Acta Cytol. 1993 Jan-Feb;37(1):93-6. Unique Identifier : AIDSLINE MED/93166839; Teot LA; Ducatman BS; Geisinger KR; Department of Pathology, Wake Forest University, Bowman Gray; School of Medicine, Winston-Salem, North Carolina.; Cytomegalovirus ( CMV ) is recognized as a common cause of infectious esophagitis in patients with the acquired immunodeficiency syndrome (AIDS). The radiographic and endoscopic findings are variable, and although some features are suggestive of CMV esophagitis, n
Solid phase DNA minisequencing by an enzymatic luminometric inorganic pyrophosphate detection assay.: Anal Biochem. 1993 Jan;208(1):171-5. Unique Identifier : AIDSLINE MED/93167538; Nyren P; Pettersson B; Uhlen M; Department of Biochemistry and Biotechnology, Royal Institute of; Technology, Stockholm, Sweden.; A solid phase DNA sequencing method for non-radioactive detection of single base changes without the need for electrophoresis is presented. The concept relies on the detection of DNA polymerase activity by an enzymatic luminometric inorganic pyrophosphate detection assay (P. Nyren, 1987, Anal. Biochem. 167, 235-238).
Systemic antivirals in herpesvirus infections.: Dermatol Clin. 1993 Jan;11(1):171-85. Unique Identifier : AIDSLINE MED/93169809; Sasadeusz JJ; Sacks SL; Department of Medicine, University of British Columbia,; Vancouver, Canada.; Over the last few years we have seen the advent of effective antiviral drug therapy, the major ramifications being in the area of herpes infections. Acyclovir has become an established part of clinical practice, and other compounds are being increasingly used in the immunocompro
gp51 of bovine leukemia virus gene expression in hamster cells.: Int J Cancer. 1993 Feb 20;53(4):640-4. Unique Identifier : AIDSLINE MED/93170941; Slavikova K; Zajac V; Klobusicka M; Aida Y; Stevurkova V; Cancer Research Institute, Slovak Academy of Sciences, Department; of Experimental Pathology, Bratislava, Czechoslovakia.; Recombinant pMMEx-bovine leukemia virus env gene DNA fragments were produced and expressed in eukaryotic cells. Clone C4, containing an SmaI-SmaI fragment of the gene coding for gp51, was co-transfected with pSV2neo DNA into Chinese hamster cells. About 800 geneticin-resistant cell clones were isolated and then morpho
Defective T cell receptor-mediated signaling and differential induction of T cell functions by murine AIDS virus superantigen.: J Immunol. 1993 Mar 1;150(5):1865-72. Unique Identifier : AIDSLINE MED/93171612; Kanagawa O; Wiebenga ME; Vaupel BA; Department of Pathology and Medicine, Washington University; School of Medicine, St. Louis, MO 63110.; A B cell line, B6-1710, expressing murine AIDS virus superantigen stimulates T cell hybridomas derived from a Ld-specific CTL clone to produce IL-2 regardless of their CD4/CD8 phenotype. However, B6-1710 cell did not stimulate the original CTL clone, L3, in either prol
Delayed progression of a murine retrovirus-induced acquired immunodeficiency syndrome in X-linked immunodeficient mice.: J Exp Med. 1993 Mar 1;177(3):621-6. Unique Identifier : AIDSLINE MED/93171802; Hitoshi Y; Okada Y; Sonoda E; Tominaga A; Makino M; Suzuki K; Kinoshita J; Komuro K; Mizuochi T; Takatsu K; Department of Immunology, University of Tokyo, Japan.; The murine acquired immunodeficiency syndrome (MAIDS) caused by defective LP-BM5 murine leukemia virus (MuLV) is a disease that shows severe immunodeficiency with abnormal lymphoproliferation, and hypergammaglobulinemia in susceptible C57BL/6 (B6) mice. To examine the cellular mechanisms of development of MAIDS, we in
Translation of equine infectious anemia virus bicistronic tat-rev mRNA requires leaky ribosome scanning of the tat CTG initiation codon.: J Virol. 1993 Mar;67(3):1433-40. Unique Identifier : AIDSLINE MED/93172362; Carroll R; Derse D; Laboratory of Viral Carcinogenesis, National Cancer; Institute-Frederick Cancer Research Center, Maryland 21702-1201.; We have examined the translational regulation of the equine infectious anemia virus (EIAV) bicistronic tat-rev mRNA. Site-directed mutagenesis of the tat leader region followed by expression of the tat-rev cDNA both in vitro and in transiently transfected cells established that tat translation is initiated exclusively
A distinct African lentivirus from Sykes' monkeys.: J Virol. 1993 Mar;67(3):1517-28. Unique Identifier : AIDSLINE GENBANK/L06042; Hirsch VM; Dapolito GA; Goldstein S; McClure H; Emau P; Fultz PN; Isahakia M; Lenroot R; Myers G; Johnson PR; Laboratory of Infectious Diseases, National Institute of Allergy; and Infectious Diseases, Rockville, Maryland 20852.; Asymptomatic infection with simian immunodeficiency virus (SIV) has been demonstrated in African Sykes monkeys (Cercopithecus mitis albogularis), and virus isolation confirmed infection with a novel SIV from Sykes monkeys (SIVsyk). Macaques inoculated with SIVsyk became persistently infected but remained clinically
Influence of human T-cell leukemia virus type I tax and rex on interleukin-2 gene expression.: J Virol. 1993 Mar;67(3):1590-9. Unique Identifier : AIDSLINE MED/93172379; McGuire KL; Curtiss VE; Larson EL; Haseltine WA; Department of Biology and Molecular Biology Institute, College of; Sciences, San Diego State University, California 92182-0057.; The X region of human T-cell leukemia virus type I (HTLV-I) encodes two proteins that regulate viral gene expression. The tax protein is the product of the transactivator gene and has been shown to up-regulate the expression of some cellular genes controlling T-cell replication, including that of the interleukin-2 (
Recommendations for HIV testing services for inpatients and outpatients in acute-care hospital settings. Center for Disease Control and Prevention.: MMWR Morb Mortal Wkly Rep. 1993 Jan 15;42(RR-2):1-6. Unique Identifier : AIDSLINE MED/93173024; These recommendations update previous recommendations regarding human immunodeficiency virus (HIV) counseling and testing of patients in acute-care hospital settings (1). The revision was prompted by additional information regarding both the rates at which patients admitted to some acute-care hospitals have unrecogniz
Technical guidance on HIV counseling. Center for Disease Control and Prevention.: MMWR Morb Mortal Wkly Rep. 1993 Jan 15;42(RR-2):11-7. Unique Identifier : AIDSLINE MED/93173025; Human immunodeficiency virus counseling and testing services (HIV-CTS) have been recommended by CDC since 1985, when serologic tests became available to detect antibodies to HIV (1,2). In August 1987, CDC published the Public Health Service Guidelines for Counseling and Antibody Testing to Prevent HIV Infection and AI
2',3'-dideoxycytidine (ddC) toxic neuropathy: a study of 52 patients.: Neurology. 1993 Feb;43(2):358-62. Unique Identifier : AIDSLINE MED/93173310; Berger AR; Arezzo JC; Schaumburg HH; Skowron G; Merigan T; Bozzette S; Richman D; Soo W; Department of Neurology, Albert Einstein College of Medicine,; Bronx, NY.; We administered the antiviral agent 2 ,3 -dideoxycytidine ( ddC ) to HIV-infected patients with either ARC or AIDS as part of the AIDS Clinical Treatment Group protocol 012 and serially evaluated them with neuropathic symptom questionnaires, neurologic
Field loss in CMV retinitis [letter; comment]: Ophthalmology. 1993 Feb;100(2):148-9. Unique Identifier : AIDSLINE MED/93173460; Dreyer EB
Post-translational processing of the feline immunodeficiency virus envelope precursor protein.: Virology. 1993 Mar;193(1):433-8. Unique Identifier : AIDSLINE MED/93174954; Verschoor EJ; Hulskotte EG; Ederveen J; Koolen MJ; Horzinek MC; Rottier PJ; Department of Virology, Veterinary Faculty, State University of; Utrecht, The Netherlands.; The synthesis and processing of the envelope glycoprotein precursor of the feline immunodeficiency virus (FIV) isolate FIV-UT113 was investigated in a persistently infected Crandell feline kidney cell line (CRFK) and in an eukaryotic expression system. Pulse-chase studies showed two glycoproteins after a 5 min pulse-l
Tissue tropism of avian leukosis viruses: analyses for viral DNA and proteins.: Virology. 1993 Mar;193(1):443-5. Unique Identifier : AIDSLINE MED/93174956; Robinson HL; Ramamoorthy L; Collart K; Brown DW; Department of Pathology, Unversity of Massachusetts Medical; Center, Worcester 01655.; Analyses of six tissues from Rous-associated virus type 1-infected chickens have revealed a number of tissue-specific differences in virus synthesis and distribution. Chicks were infected at 1 day of age. Tissue (bursa, thymus, liver, kidney, muscle, and brain) were harvested 1 month later. Each of the tissues contain
Drug approval for weight loss in AIDS [news]: Am Fam Physician. 1993 Mar;47(4):997. Unique Identifier : AIDSLINE MED/93175282
Detection of cytomegalovirus in the gastrointestinal tract: seeking a gold standard [editorial; comment] [see comments]: Am J Gastroenterol. 1993 Mar;88(3):332-3. Unique Identifier : AIDSLINE MED/93175447; Bonacini M; Laine L
Frequency of positive tests for cytomegalovirus in AIDS patients: endoscopic lesions compared with normal mucosa [see comments]: Am J Gastroenterol. 1993 Mar;88(3):338-43. Unique Identifier : AIDSLINE MED/93175449; Goodgame RW; Genta RM; Estrada R; Demmler G; Buffone G; Department of Medicine, Baylor College of Medicine, Houston,; Texas.; Ten patients with the acquired immunodeficiency syndrome and an endoscopic erosive/ulcerative lesion in esophagus (4), stomach (3), or colon (3) were prospectively studied with multiple biopsies (244 biopsies from 33 sites) to determine: 1) the frequency of positive tests for cytomegal
ANA publishes brochure on bloodborne diseases.: Am Nurse. 1993 Feb;25(2):2. Unique Identifier : AIDSLINE MED/93175729
Guidelines for counseling persons infected with human T-lymphotropic virus type I (HTLV-I) and type II (HTLV-II). Centers for Disease Control and Prevention and the U.S.P.H.S. Working Group.: Ann Intern Med. 1993 Mar 15;118(6):448-54. Unique Identifier : AIDSLINE MED/93175796; The human T-lymphotropic viruses type I (HTLV-I) and type II (HTLV-II) are closely related but distinct retroviruses that can infect humans. They differ from the human immunodeficiency viruses that cause the acquired immunodeficiency syndrome. Screening of the U.S. blood supply for HTLV-I/II, which began in 1988, iden
Parathyroid hormone and T-cellular immunity in uremic patients in replacement dialytic therapy.: Artif Organs. 1993 Feb;17(2):73-5. Unique Identifier : AIDSLINE MED/93176049; Angelini D; Carlini A; Giusti R; Grassi R; Mei E; Fiorini I; Mazzotta L; Antonelli A; Department of Nephrology, Hospital of Lucca, Italy.; We studied 54 patients in replacement dialytic therapy divided into two groups: Group 1, 26 patients with normal parathyroid hormone (PTH) (10-80 pg/ml): and Group 2, 28 patients with elevated PTH (80-400 pg/ml). Total T lymphocytes, CD4, CD8, and CD4/CD8 ratio were evaluated. We found a reduction of total T lymphocyt
Control of cytomegalovirus retinitis using sustained release of intraocular ganciclovir [see comments]: Arch Ophthalmol. 1993 Feb;111(2):223-7. Unique Identifier : AIDSLINE MED/93159377; Anand R; Nightingale SD; Fish RH; Smith TJ; Ashton P; Department of Ophthalmology, University of Texas Southwestern; Medical Center, Dallas.; An experimental intravitreal sustained-release device containing ganciclovir was used to treat 22 patients with acquired immunodeficiency syndrome-associated cytomegalovirus retinitis. Fourteen eyes were excluded (five not involved and nine with macular scarring and/or severe debil
Benign parotid cysts associated with human immunodeficiency virus infection [see comments]: Br J Surg. 1993 Jan;80(1):39. Unique Identifier : AIDSLINE MED/93153588; Barr LC; Cox PJ; Maskell GF; Thomas JM; Department of Surgery, Royal Marsden Hospital, London, UK.
The natural history of HIV infection: implications for the assessment of antiretroviral therapy.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S2-6. Unique Identifier : AIDSLINE MED/93144546; Corey L; Coombs RW; Department of Laboratory Medicine, University of Washington,; Seattle.; Although AIDS is a complex clinical disease with diverse manifestations, infection with human immunodeficiency virus (HIV) per se is almost entirely subclinical. The evaluation of antiretroviral agents is difficult because of the lack of a direct clinical relationship between the replication of HIV and the subsequent
Surrogate markers in AIDS clinical trials: conceptual basis, validation, and uncertainties.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S22-5. Unique Identifier : AIDSLINE MED/93144547; Lagakos SW; Department of Biostatistics, Harvard School of Public Health,; Boston, Massachusetts 02115.; The identification of surrogate markers for clinical end points has important implications for the conduct of AIDS clinical trials, the approval of drugs for the treatment of infection with human immunodeficiency virus (HIV), and the management of HIV infection. In this paper, the concept of a surrogate marker and the
Relation between plasma concentrations of didanosine and markers of antiviral efficacy in adults with AIDS or AIDS-related complex.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S26-31. Unique Identifier : AIDSLINE MED/93144548; Beltangady M; Knupp CA; Gustafson N; Barbhaiya RH; Dolin R; Seidlin M; Cooley TP; Rozencweig M; Bristol-Myers Squibb Pharmaceutical Research Institute,; Wallingford, Connecticut 06492.; The relation between the average steady-state plasma concentration (Cpss) of didanosine and selected measures of efficacy, such as CD4 cell count, p24 antigenemia, and weight gain, was evaluated in patients participating in a phase 1 safety and pharmacokinetics study. All patients were diagnosed as having AIDS or seve
Didanosine: long-term follow-up of patients in a phase 1 study.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S40-5. Unique Identifier : AIDSLINE MED/93144550; Lambert JS; Seidlin M; Valentine FT; Reichman RC; Dolin R; Department of Medicine, University of Rochester School of; Medicine and Dentistry, New York 14642.; Long-term follow-up of 44 patients with AIDS or AIDS-related complex (ARC) in a phase 1 trial of didanosine is reported. These patients were monitored for as long as 72 weeks (mean, 34 weeks) for toxicity and activity of didanosine. Pancreatitis and neuropathy, the major clinical toxicities, developed infrequently at
Didanosine in the treatment of AIDS and AIDS-related complex: a critical appraisal of the dose and frequency of administration.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S52-8. Unique Identifier : AIDSLINE MED/93144552; Liebman HA; Cooley TP; Department of Medicine, University of Southern California School; of Medicine, Los Angeles 90033.; In the summer of 1988, dose-finding phase 1 trials of the efficacy and safety of didanosine were begun by investigators at the National Cancer Institute (NCI), by the AIDS Clinical Trials Group (ACTG) at New York University School of Medicine and the University of Rochester School of Medicine, and by researchers at Bo
Use of didanosine in zidovudine-intolerant patients infected with human immunodeficiency virus.: Clin Infect Dis. 1993 Feb;16 Suppl 1:S59-62. Unique Identifier : AIDSLINE MED/93144553; Nelson MR; Moyle GJ; Gazzard BG; HIV/GUM Unit, St. Stephen's Clinic, London, United Kingdom.; One hundred fifty-one patients who were positive for antibody to human immunodeficiency virus (HIV) and intolerant of zidovudine received oral didanosine at a dose adjusted by weight to a maximum of 12.5 mg/(kg.d). After 1 year of follow-up, 49 patients were still receiving didanosine; 19 had died during therapy and 2
Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: differential CTL responses to HIV-1 and Epstein-Barr virus in late disease.: J Exp Med. 1993 Feb 1;177(2):249-56. Unique Identifier : AIDSLINE MED/93147714; Carmichael A; Jin X; Sissons P; Borysiewicz L; Department of Medicine, University of Cambridge Clinical School,; United Kingdom.; Major histocompatibility complex (MHC)-restricted cytotoxic T lymphocytes (CTL) are part of the cellular immune response to human persistent virus infections. Measurements of the frequency and specificity of human immunodeficiency virus type 1 (HIV-1)-specific CTL and their variation with time may indicate their relat
Prolonged immunostimulatory effect of low-dose polyethylene glycol interleukin 2 in patients with human immunodeficiency virus type 1 infection.: J Exp Med. 1993 Feb 1;177(2):483-92. Unique Identifier : AIDSLINE MED/93147738; Teppler H; Kaplan G; Smith KA; Montana AL; Meyn P; Cohn ZA; Laboratory of Cellular Physiology and Immunology, Rockefeller; University, New York, New York 10021.; 13 patients with human immunodeficiency virus type 1 infection class II-IV, but without opportunistic infection or neoplasm, received 6 micrograms (3.6 x 10(4) IU) of polyethylene glycol recombinant human interleukin 2 (PEG IL-2 ) intradermally twice a week for 4 mo wer
Clinical Advances in the Treatment of HIV Disease. Symposium proceedings. Sydney, Australia, May 29-31, 1992.: J Acquir Immune Defic Syndr. 1993;6 Suppl 1:S1-86. Unique Identifier : AIDSLINE MED/93148104
Mycoplasma fermentans in individuals seropositive and seronegative for HIV-1 [see comments]: Lancet. 1993 Jan 30;341(8840):271-3. Unique Identifier : AIDSLINE MED/93148720; Katseni VL; Gilroy CB; Ryait BK; Ariyoshi K; Bieniasz PD; Weber JN; Taylor-Robinson D; Department of Genitourinary Medicine and Communicable Diseases,; St Mary's Hospital Medical School, London, UK.; Mycoplasmas have been suggested as a co-factor to explain various puzzling features of infection by human immunodeficiency virus 1 (HIV-1). We sought Mycoplasma fermentans by means of a semi-nested polymerase chain reaction (PCR) in samples of peripheral-blood mononuclear cells (PBMC), throat swabs, and urine samples
Disappearing delegates [letter]: Lancet. 1993 Jan 30;341(8840):311. Unique Identifier : AIDSLINE MED/93148754; Fraser I; Abbott M
Clearance of HIV-1 viraemia after seroconversion [letter; comment]: Lancet. 1993 Jan 30;341(8840):315-6. Unique Identifier : AIDSLINE MED/93148765; Clementi M; Bagnarelli P; Menzo S; Valenza A; Manzin A; Varaldo PE
The relationship of serum DHEA-S and cortisol levels to measures of immune function in human immunodeficiency virus-related illness.: Am J Med Sci. 1993 Feb;305(2):79-83. Unique Identifier : AIDSLINE MED/93151283; Wisniewski TL; Hilton CW; Morse EV; Svec F; Department of Medicine, Louisiana State University Medical; Center, New Orleans.; Human immunodeficiency virus (HIV) is a major cause of immunoincompetence. Whether the virus, itself, accounts for all the deficiency remains in question. Steroids can also influence immune function; glucocorticoids cause immunoincompetence while dehydroepiandrosterone (DHEA) enhances immune function. Changes in the l
A human lymphoid recombinant cell line with functional human immunodeficiency virus type 1 envelope.: AIDS Res Hum Retroviruses. 1993 Jan;9(1):23-32. Unique Identifier : AIDSLINE MED/93152283; Jonak ZL; Clark RK; Matour D; Trulli S; Craig R; Henri E; Lee EV; Greig R; Debouck C; Department of Cellular Biochemistry, SmithKline Beecham; Pharmaceuticals, King of Prussia, PA 19406-2799.; Our goal has been to develop a safe and effective system that would allow us to explore the functions of the human immunodeficiency virus (HIV) envelope. We have generated a human lymphoid cell line (TF228.1.16) that stably expresses functional HIV envelope proteins on its cell surface, and therefore closely mimics th
Multicenter, randomized, placebo-controlled study of ditiocarb (Imuthiol) in human immunodeficiency virus-infected asymptomatic and minimally symptomatic patients. The HIV87 Study Group.: AIDS Res Hum Retroviruses. 1993 Jan;9(1):83-9. Unique Identifier : AIDSLINE MED/93152291; Ditiocarb sodium has been reported to reduce the progression of human immunodeficiency virus (HIV) infection. To confirm this therapeutic activity and to evaluate the effect of ditiocarb sodium in the early stages of HIV infection, we conducted a randomized, double-blind, placebo-controlled trial in asymptomatic or mi
The role of factor XIIIa-positive dermal dendrocytes in HIV-1-positive psoriatics.: Br J Dermatol. 1993 Jan;128(1):29-33. Unique Identifier : AIDSLINE MED/93152475; van Neer F; Zemelman V; Cerio R; Langtry J; Staughton RC; Skin and Therapeutics Research Laboratory, Westminster Hospital,; London, U.K.; Factor XIIIa-positive dermal dendrocytes (FXIIIa+ dd) may have an important role in the pathogenesis of psoriasis, in that their numbers are increased in lesional skin compared with non-lesional skin. Moreover, in AIDS-associated Kaposi s sarcoma the number of these cells is also increased, in comparison with the clas
Prognostic value of serum immunoglobulin A antibodies to pol gene products during HIV-1 infection.: Clin Exp Immunol. 1993 Feb;91(2):237-40. Unique Identifier : AIDSLINE MED/93153899; Quesnel A; Pozzetto B; Moja P; Grattard F; Lucht FR; Touraine JL; Gaudin OG; Genin C; Department of Immunology, Faculty of Medicine Jacques Lisfranc,; Saint-Etienne, France.; Serum specimens from 66 HIV-1-infected subjects were tested by ELISA for the presence of IgA antibodies to HIV-1: 44 samples were found positive and 37 were confirmed by immunoblot. In these subjects, the presence of anti-HIV IgA antibodies was studied in relation to the total count of circulating CD4+ lymphocytes and
Differential requirements for HIV-1 replication in naive and memory CD4 T cells from asymptomatic HIV-1