Affinity and concentration of anti-HIV antibodies in asymptomatic and symptomatic HIV infection. NLM AIDSLINE Important note: Information in this article was accurate in 1993. The state of the art may have changed since the publication date.

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Affinity and concentration of anti-HIV antibodies in asymptomatic and symptomatic HIV infection.

Mater Med Pol. 1991 Oct-Dec;23(4):256-8. Unique Identifier : AIDSLINE MED/93078437
Radkowski M; Laskus T; Goch A; Slusarczyk J; Department of Immunopathology, Institute of Infectious and; Parasitic Diseases, Warszawa, Poland.

Abstract: A novel method based on dose-response curve of antibodies and employing a hyperbolic function for its description was used for the assessment of the affinity and concentration of anti-HIV antibodies in eighteen anti-HIV positive males. The patients were followed up for a period of 8 months to 5 years and affinity and concentration of antibodies were measured at least twice, at the beginning and at the end of the observation period. No correlation between antibodies affinity and the clinical stage of infection was observed, however, concentration of antibodies decreased rapidly in AIDS.
Keywords: Acquired Immunodeficiency Syndrome/*IMMUNOLOGY Adult *Antibody Affinity Antigen-Antibody Reactions Comparative Study Enzyme-Linked Immunosorbent Assay Human HIV Antibodies/ANALYSIS/*IMMUNOLOGY HIV Seropositivity Male Middle Age JOURNAL ARTICLEKWDacquiredimmunodeficiencysyndrome/KWDimmunologyadultKWDantibodyaffinityantigen-antibodyreactionscomparativestudyenzyme-linkedimmunosorbentassayhumanhivantibodies/analysis/KWDimmunologyhivseropositivitymalemiddleagejournalarticle
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M9331088

Copyright © 1993 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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