Subclinical neuropathy in children with inherited haemostasis disorders. NLM AIDSLINE Important note: Information in this article was accurate in 1993. The state of the art may have changed since the publication date.

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Subclinical neuropathy in children with inherited haemostasis disorders.

Electromyogr Clin Neurophysiol. 1992 Oct-Nov;32(10-11):511-4. Unique Identifier : AIDSLINE MED/93076653
Stamboulis EJ; Syrigou-Papavasiliou A; Platokouki HG; Mitsika AP; Aronis SA; Department of Neurology Medical School, University of Athens,; Greece.

Abstract: Motor and sensory conduction of the right peroneal and sural nerves was studied in 28 children (17 HIV seropositive) with inherited hemostasis disorders, without any symptoms of neuropathy. The amplitude ratio of the evoked muscle potential (EMP) at distal stimulation to that at proximal stimulation at the right peroneal nerve was also studied. Thirty healthy aged-matched children were used as controls. There was no statistically significant difference in the distal latency, amplitude and conduction velocity of motor and sensory nerves between patients and controls. On the contrary, a great diminution of amplitude of the EMP during proximal stimulation of nerve was observed in patients, statistically very significant, as compared to controls. This difference was independent of patients' age, severity of hemostasis defect or HIV status. In 9 patients the amplitude was within normal limits. Intraneural oozing due to trivial trauma is postulated as a possible mechanism of peroneal nerve lesion.
Keywords: Action Potentials/PHYSIOLOGY Adolescence Child Female Hemorrhagic Diathesis/COMPLICATIONS/*PHYSIOPATHOLOGY Human HIV Infections/COMPLICATIONS/PHYSIOPATHOLOGY Male Nervous System Diseases/ETIOLOGY/*PHYSIOPATHOLOGY Neural Conduction/PHYSIOLOGY Reaction Time/PHYSIOLOGY JOURNAL ARTICLEKWDactionpotentials/physiologyadolescencechildfemalehemorrhagicdiathesis/complications/KWDphysiopathologyhumanhivinfections/complications/physiopathologymalenervoussystemdiseases/etiology/KWDphysiopathologyneuralconduction/physiologyreactiontime/physiologyjournalarticle
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M9331063

Copyright © 1993 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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