Infectious SRV in excreta of viremic M. nemestrina? NLM AIDSLINE Important note: Information in this article was accurate in 1993. The state of the art may have changed since the publication date.

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Infectious SRV in excreta of viremic M. nemestrina?

Symp Nonhum Primate Models AIDS. 1992 Nov 17-20;10:abstract no. 110. Unique Identifier : AIDSLINE PRIM10/93200955
Welch MJ; Moazed TC; Morton WR; University of Washington Regional Research Primate Center,; Seattle.

Abstract: SRV is a naturally occurring type D retrovirus which causes disease in macaque species. After exposure to SRV, most macaques become nonviremic seropositive and show no clinical signs of SRV infection. However, a small number become persistently viremic, displaying only mild clinical signs of SRV infection. Previous studies have shown SRV infection to be spread by direct contact between a viremic animals and susceptible cage-mates. The prevention of close contact between viremic and previously unexposed animals is essential to control the spread of the virus. Infectious SRV is routinely isolated from the peripheral blood mononuclear cells of viremic macaques, but has also been isolated from saliva and urine. If infectious virus is shed in excreta, could SRV spread to adjacently housed, susceptible animals? To investigate this, we examined colon washes, feces and urine samples for viable SRV.
Keywords: Animal Colon/MICROBIOLOGY Feces/*MICROBIOLOGY Macaca nemestrina/*MICROBIOLOGY Retroviridae Infections/PREVENTION & CONTROL/TRANSMISSION Retroviruses Type D, Simian/*ISOLATION & PURIF Urine/*MICROBIOLOGY ABSTRACTKWDanimalcolon/microbiologyfeces/KWDmicrobiologymacacanemestrina/KWDmicrobiologyretroviridaeinfections/prevention&control/transmissionretrovirusestyped,simian/KWDisolation&purifurine/KWDmicrobiologyabstract
930630
M9361065

Copyright © 1993 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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