1993

Infectious disease complications of children with AIDS. [videorecording]: [Houston, Tex.] : UT-TV, Houston, c1990 1 videocassette (60 min.) : sd., col. ; 1/2 in (Pediatric grand rounds) Unique Identifier : AIDSLINE AV/9300772A; Pickering LK
Why me : dealing with an occupational exposure to a bloodborne virus. [videorecording]: [Nashville, Tenn.] : Envision [and] VU, VUMC, c1992 1 videocassette (15 min.) : sd., col. ; 1/2 in Unique Identifier : AIDSLINE AV/9300756A; (Producer) In today s high-risk health care environment, the fear of exposure to bloodborne viruses is ever-present. This program speaks to the health care worker who has been exposed to Hepatitis or AIDS/HIV. Showing a cross section of health care workers talking to a hospital representative, the significance of th
[Ai tzu ping = (AIDS).] Ti 1 pan.: [Hang-chou] : Che-chiang ta hsueh ch'u pan she, 1987 117 p Unique Identifier : AIDSLINE CAT/9308230; Hsiang I
[AIDS, apokalyptische Warnung Gottes?.]: Furth-Erlenbach : Verlag P. Assmus, c1987 144 p (KLETOS-Taschenbuch ; 105) Unique Identifier : AIDSLINE CAT/9308741; Quadflieg K
[Aids og unge.] 2. udg., 2. opl.: [S.l.] : Munksgaard, 1988, c1986 47 p. : ill Unique Identifier : AIDSLINE CAT/9308231; Lauest S
AIDS and drug misuse : report.: London : H.M.S.O., 1988- v Unique Identifier : AIDSLINE CAT/9308255
[Nihon no eizu shorei = Aids cases in Japan.]: Tokyo : Nihon Koshu Eisei Kyokai, 1988 217 p. : ill Unique Identifier : AIDSLINE CAT/9308515; Shiokawa Y
[Sauver des vies : stopper le sida.]: [Dakar?] : Edition Afrique de l'Ouest,, 1988 printing 12 p. : ill Unique Identifier : AIDSLINE CAT/9309053
[Eizu : HIV boshi kansen yobo no gaidorain.]: Tokyo : Dobun Shoin, 1988 3, 3, 206 p., 7 p. of plates : ill Unique Identifier : AIDSLINE CAT/9309271
Local AIDS policies.: Washington, DC : The Conference, c1988 79 p Unique Identifier : AIDSLINE CAT/9309385
Report of the working panel on discrimination and other legal issues, HIV/AIDS.: [Canberra] : Dept. of Community Services and Health, [1989] xiii, 43 leaves (Consultation paper ; no. 2) Unique Identifier : AIDSLINE CAT/9308135
Report of the working panel on intravenous drug use and HIV/AIDS.: [Canberra] : Dept.of Community Services and Health, [1989] vii, 15 leaves (Consultation paper ; no. 4) Unique Identifier : AIDSLINE CAT/9308136
[AIDS.]: Frankfurt am Main : Behringwerke AG, Medizinische Information und Verkauf, [1989?] 152 p. : ill (Behring Diagnostika) Unique Identifier : AIDSLINE CAT/9308739; Feldner J
[Liebe als Prufstein : Wurzel und Heilung von Aids.] 2. Aufl.: Leutesdorf : Johannes-Verlag, 1989 31 p. : ill., port (Aktuelle Schriften) Unique Identifier : AIDSLINE CAT/9308927; Thurkauf M
[Las:Pruebas clinicas para el SIDA : como participar.]: [Bethesda, Md.] : Departamento de Salud y Servicios Humanos de los EE.UU, Servicio de Salud Publica, Institutos Nacionales de Salud, Instituto Nacional de Alergias y Enfermedades Infecciosas, c1993 v, 34 p. : ill (NIH publication ; no. 89-3025S) Unique Identifier : AIDSLINE CAT/9309021
Perspectives on the AIDS crisis : thanatologic aspects.: New York : Foundation of Thanatology, c1989 137 p (The Current thanatology series) Unique Identifier : AIDSLINE CAT/9309450; Lampke RS
State policies and the financing of AIDS care.: Santa Monica, CA : Rand Corp., [1989] ix, 32 p (A Rand note ; N-2942-HCFA) Unique Identifier : AIDSLINE CAT/9309521; Pascal AH
[AIDS im Blut : eine Naturheilmethode gegen AIDS, Gicht, Krebs, Steinbildungen.]: Steyr : Verlag W. Ennsthaler, c1990 62 p Unique Identifier : AIDSLINE CAT/9308257; Waldner M
Duration and costs of AIDS hospitalizations in New York.: Rockville, MD : U.S. Dept. of Health and Human Services, Public Health Service, Agency for Health Care Policy and Research, 1990 i p., p. 1085-1098 : ill Unique Identifier : AIDSLINE CAT/9308328; Kelly JV
Local AIDS services : the national directory.: Washington, DC (1620 Eue St.. N.W., 4th Floor, Washington 20008) : United States Conference of Mayors, c1990 233 p Unique Identifier : AIDSLINE CAT/9308470
Proceedings of the AIDS in Asia and Pacific Conference, 5-8 August 1990, Canberra, Australia.: [Canberra? : The Dept., 1990?] iv, 261 p. : ports Unique Identifier : AIDSLINE CAT/9308564
[Drogen und Alkohol : Folgeschaden und Uberlebenshilfe.]: Lausanne : ISPA-PRESS, c1990 140 p. : ill Unique Identifier : AIDSLINE CAT/9308797
[SIDA : la medecine du travail interroge les medecins du travail sur les enjeux, les perspectives, les solutions : Avignon, le vendredi 26 mai 1989.]: Montpellier : Association PRO.PER.MET, [1990] 179 p. : ill (Collection des Journees a theme de PROPERMET) Unique Identifier : AIDSLINE CAT/9309076
Fourth National Conference on AIDS : 8-11 August 1990, National Convention Centre, Canberra, ACT.: Curtin, ACT : Conference Secretariat, Conference Solutions, [1990?] xii, 168 p Unique Identifier : AIDSLINE CAT/9309293
[Kondome na sicher : eine Broschure uber Empfangnisverhutung und Schutz vor Ansteckung.]: Wien : Verlag Wilhelm Maudrich, 1990 47 p. : ill Unique Identifier : AIDSLINE CAT/9309363; Klier C
The:3rd epidemic : repercussions of the fear of AIDS.: Budapest ; Washington : Panos Institute, 1990 iv, 320 p. : ill (Panos dossier) Unique Identifier : AIDSLINE CAT/9309579
[Der:homosexuelle Mann im Zeichen von Aids.] 1. Aufl.: Hamburg : KleinVerlag, 1991 104 p Unique Identifier : AIDSLINE CAT/9308195; Dannecker M
AIDS and public policy : a selective bibliography of recent references.: Monticello, Ill., USA : Vance Bibliographies, [1991] 17 p (Public administration series, bibliography, ISSN 0193-970X ; [no.] P 3073) Unique Identifier : AIDSLINE CAT/9308256; Christensen JO
Canadian AIDS news. Vol. 5, no. 1 (Nov./Dec. 1991)-: Program Ottawa : Canadian Public Health Association, 1991- v. : ill Unique Identifier : AIDSLINE CAT/9308285
Clinical manual for care of the adult patient with HIV infection. Supplement.: Sherborn, Mass. (Box 306, Sherborn 01770) : ADLB Publications, c1991 116 p Unique Identifier : AIDSLINE CAT/9308300; Libman H; Witzburg RA
[AIDS in der Zahnarztpraxis.]: Stuttgart ; New York : Thieme, 1991 vii, 79 p., viii p. of plates : ill (Dent-Praxis) Unique Identifier : AIDSLINE CAT/9308737; Grassi M
AIDS strategic monitor : report on the survey period January-December 1989.: London : Health Education Authority, c1991 1 v. (various pagings) : ill Unique Identifier : AIDSLINE CAT/9308738
AIDS/HIV infection : a select bibliography of articles in South African journals, 1988-1990.: Pietermaritzburg : Natal Society Library, 1991 89 p Unique Identifier : AIDSLINE CAT/9308740; Bowen JH
AIDS health services at the crossroads : lessons for community care.: Princeton, N.J. : Robert Wood Johnson Foundation, [1991] viii, 136 p Unique Identifier : AIDSLINE CAT/9309185; Weisfeld VD
AIDS : opposing viewpoints.: San Diego, CA : Greenhaven Press, c1992 215 p. : ill (Opposing viewpoints series) Unique Identifier : AIDSLINE CAT/9307968; Biskup MD; Swisher K; Includes articles that present different viewpoints on such aspects of AIDS as the seriousness of the problem, moral issues, prevention, and treatment. Includes critical thinking activities.
Beyond disease : a conceptual analysis of the language and origins of the meaning of AIDS in a socio-historic and and medical context.: [Philadelphia, Pa.? : s.n., 1990?] ix, 166 p Unique Identifier : AIDSLINE CAT/9308267; Gould CA
Nine ounces : a nine-part program for the prevention of AIDS in HIV-positive persons. Rev. ed.: Boulder, CO : Blue Poppy Press, 1992 Unique Identifier : AIDSLINE CAT/9308519; Flaws B
[Infection par le VIH : repertoire des essais therapeutiques en France : methodologie, legislation et reglementations, bonnes pratiques cliniques, les protocoles, les produits, les sites.] Ed. 1992.: [Paris] : Arcat-sida, 1992 246 p Unique Identifier : AIDSLINE CAT/9308879
[Mit HIV-positiv positiv leben : 15 Schritte zur Starkung des Immunsystems : Ratgeber fur Betroffene und alle ihnen Nahestehenden.]: Zurich : Fachverlag AG, c1992 160 p Unique Identifier : AIDSLINE CAT/9308954; Kagi C
Opportunistic complications of HIV. Vol 1, no 1-: Philadelphia, PA : Meniscus Health Care Communications, c1992- v. : ill Unique Identifier : AIDSLINE CAT/9308988
AIDS agenda : emerging issues in civil rights. 1st ed.: New York : New Press, c1992 xv, 301 p Unique Identifier : AIDSLINE CAT/9309184; Hunter ND; Rubenstein WB
[AIDS und Strafzumessung.]: Frankfurt am Main ; New York : Lang, c1992 v, 121 p (Frankfurter kriminalwissenschaftliche Studien, ISSN 0170-6918 ; Bd. 38) Unique Identifier : AIDSLINE CAT/9309186; Nestler-Tremel C
Nutrition & HIV/AIDS : proceedings of the ... International Symposium on Nutrition and HIV/AIDS, including the nutrition algorithm and nutrition initiative of the Physicians Association for AIDS Care. Vol. 1 (1992)-: Chicago, Ill. : PAAC Pub., Inc., c1992- v. : ill Unique Identifier : AIDSLINE CAT/9308984
The:Central nervous system in AIDS : neurology, radiology, pathology, ophthalmology.: Berlin ; New York : Springer-Verlag, c1993 vi, 237 p. : ill Unique Identifier : AIDSLINE CAT/9308289; Artigas J; Grosse G; Niedobitek F
New concepts in AIDS pathogenesis.: New York : Marcel Dekker, Inc., c1993 xiii, 323 p. : ill Unique Identifier : AIDSLINE CAT/9308511; Montagnier L; Gougeon M
Dictionary of AIDS-related terminology.: New York : Neal-Schuman, c1993 ix, 165 p Unique Identifier : AIDSLINE CAT/9309252; Huber JT; Includes definitions of over 1000 abbreviations and acronyms, historical and medical terms, key names, and sources of information found in discussions of AIDS and HIV.
AIDS abstracts : international literature on acquired immunodeficiency syndrome and related retroviruses. Vol. 9, no. 1 (Jan. 1993)-: Abingdon, Oxforshire, U.K. : Carfax Pub. Co., c1993- v Unique Identifier : AIDSLINE CAT/9309183
AIDS in Africa.: New York : Raven Press, c1994 xxii, 728 p. : ill Unique Identifier : AIDSLINE CAT/9308258; Essex M
HIV manual for health care professionals.: Norwalk, Conn. : Appleton & Lange, c1994 xix, 299 p. : ill Unique Identifier : AIDSLINE CAT/9308049; Muma RD
Textbook of AIDS medicine.: Baltimore : Williams & Wilkins, c1994 xix, 951 p. : ill Unique Identifier : AIDSLINE CAT/9308632; Broder S; Merigan TC; Bolognesi D
A study of polyoma virus-induced murine thymic epithelial tumors: a model of the thymic microenvironment.: Diss Abstr Int [B]; 52(8):4112 1992. Unique Identifier : AIDSLINE ICDB/93682284; Hoot GP; Univ. of Texas Health Science Center at Dallas; A strain of polyoma virus, PTA, induced multiple epithelial tumors when injected into neonatal C3H/Bittner mice, especially thymic epithelial and salivary epithelial tumors. Neoplastic thymic epithelium was found to coexpress ER-TR4 and ER-TR5 markers, which are mutually exclusive on normal thymic cortical and medulla
Studies of 2,5'-anhydro-3'-azido-3'-deoxythymidine (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A87 1993. Unique Identifier : AIDSLINE ICDB/93691070; Sun AS; Prusoff WH; Dept. of Pharmacology, Yale Univ. Sch. of Medicine, New Haven, CT; 06510; 2,5 -Anhydro-3 -azido-3 -deoxythymidine (anAZT) has been reported to have antiviral activity against HIV-1 in cell culture and is converted to AZT and then thymine (thy) by a human liver homogenate (LH). The properties and purification of the factors involved in the degradation of anAZT are under study. Incubation of
Interleukin-4 receptor (IL-4R) expression on AIDS-related Kaposi's sarcoma (AIDS-KS) cells and inhibition of tumor cell growth and cytokine production by IL-4 (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A1121 1993. Unique Identifier : AIDSLINE ICDB/93692092; Gill P; Puri PK; Dept. of Medicine, Univ. of Southern California, Los Angeles, CA; 90033; We have previously demonstrated that a variety of human solid tumors express high-affinity IL-4R, and IL-4 can inhibit growth of these cells in vitro. In the present study, we have examined (1) the expression of IL-4R on AIDS-KS-derived spindle cells at the tumor cell surface and gene levels and (2) the effect of IL-4
Biochemical changes in Kaposi's sarcoma and experimental therapy of murine AIDS (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A1120 1993. Unique Identifier : AIDSLINE ICDB/93692095; Ambrus JL; Stadler S; Nakeeb S; Toumbis C; Butsch J; Spatola G; Mathur N; Munschauer R; Chadha K; Dept. of Medicine, Buffalo General Hosp., Buffalo, NY 14203; In patients with Kaposi s sarcoma (KS) and AIDS, there was decreased interferon-alpha (IFN-alpha) synthesizing capacity, and in KS tissue increased amounts of prostaglandin E2 (PgE2) were found. PgE2 inhibited IFN-alpha synthesis, a cAMP-dependent process. cAMP-increasing agents (eg, pentoxifylline [PX]) and PgE2 inhi
The time of administration of 3'-azido-3'-deoxythymidine (AZT) determines its toxicity (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A1666 1993. Unique Identifier : AIDSLINE ICDB/93692607; Zhang R; Lu Z; Guttmann R; Diasio RB; Dept. of Pharmacology, Univ. of Alabama, Birmingham, AL 35294; AZT is the most widely used drug in the treatment of AIDS. Its major drug-related toxicity is bone marrow suppression, which limits the dose of AZT that can be used. It is essential that AZT be phosphorylated to AZT-MP, AZT-DP, and AZT-TP for antivira
HIV-1 integrase inhibition by flavones and caffeic acid phenethylester (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A1668 1993. Unique Identifier : AIDSLINE ICDB/93692609; Fesen MR; Horiguchi S; Leteurtre F; Kohn KW; Pommier Y; Lab. of Molecular Pharmacology, DTP, DCT, NCI, Bethesda, MD 20892; Genomic integration is essential for HIV-1 provirus expression and viral replication. We have used purified recombinant HIV-1 integrase (IN) and oligonucleotides to study the structure-activity relationship of 47 flavone derivatives. Minimal requirements for activity were hydroxylations at positions 3 ,4 , 3 and 7. Hy
A self-assembling HIV protease inhibitor (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A1674 1993. Unique Identifier : AIDSLINE ICDB/93692614; Chiang LC C; Derango R; Rideout D; Dept. of Molecular Biology, Scripps Res. Inst., La Jolla, CA; 92037; As part of an ongoing program to create antiretroviral prodrug combinations with low mol wt and high membrane permeabilities, we have developed a combination of an aldehyde A and an acylhydrazide B. An equimolar combination inhibits HIV protease with EC90 = 160 uM each, as compared to EC90 greater than or equal to 200
Modulation of drug-induced hematopoietic toxicity with zinc in murine bone marrow cells (BMC) (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A1700 1993. Unique Identifier : AIDSLINE ICDB/93692641; Gogu SR; Agrawal KC; Dept. of Pharmacology, Tulane Univ. Sch. of Medicine, New; Orleans, LA 70112; Drug-induced hematopoietic toxicity is a major limiting factor in the administration of anticancer and anti-HIV drugs. Zinc supplementation has been shown to stimulate immunological function and its deficiency to cause atrophy of the thymus and spleen. We have investigated the role of zinc in reversing zidovudine (
Continuous infusion (CI) bleomycin in AIDS-related Kaposi's sarcoma (KS) (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A1118 1993. Unique Identifier : AIDSLINE ICDB/93692094; Reddy M; Remick S; Herman D; Willis K; Grace C; McSharry J; Horton J; Harper G; Albany Medical Coll., Albany, NY 12208; Bleomycin is an active drug in KS, is cell-cycle phase-specific, and has a short terminal half-life, characteristics which make it suitable for CI. We administered 20 mg/m2/day as a 24-hr CI for 3 days to 17 patients (pts) with AIDS-related KS. All pts had biopsy-proven KS and measurable disease. Nine pts (53%) had br
Error-prone replication by HIV reverse transcriptase as a basis of drug design (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A1667 1993. Unique Identifier : AIDSLINE ICDB/93692608; Kalman TI; Jiang XJ; State Univ. of New York, Buffalo, NY 14260; An approach was devised to target error-prone HIV replication using nucleoside analogs. A prototype analog 1-(beta-D-2-deoxyribofuranosyl)-4-acetylimidazolin-2-one (imidine, dImd), a novel ring-contracted isomer of thymidine (dThd) in which the 4-carbonyl group of thymidine (dThd) is moved out of the ring to the 5-pos
Development of non-nucleoside human immunodeficiency virus type 1 (HIV-1) inhibitor which is active against HIV-1 viruses resistant to BI-RG-587 and to TIBO R82150 (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A1670 1993. Unique Identifier : AIDSLINE ICDB/93692611; Piras G; Chu SH; Dutschman GE; Im GJ; Pan BC; Chen ZH; Cheng YC; Yale Univ., New Haven, CT; 5-Ethyl-1-benzyloxymethyl-6-(alpha-pyridylseleno)uracil (E-BEPYSU), an analogue of 5-ethyl-1-benzyloxymethyl-6-(phenylthio)uracil (E-BPU) has been synthesized. It targets the reverse transcriptase enzyme inhibiting both the associated RNA- and DNA-dependent polymerase activities. It is a noncompetitive inhibitor with
Biochemical studies of the antihuman immunodeficiency virus activities of two enantiomers of 2',3'-dideoxy-3'-thiacytidine (Meeting abstract).: Proc Annu Meet Am Assoc Cancer Res; 34:A1671 1993. Unique Identifier : AIDSLINE ICDB/93692612; Skalski V; Chang CN; Dutschman GE; Cheng YC; Dept. of Pharmacology, Yale Univ., New Haven, CT 06510; Two ClS enantiomers of 2 ,3 -dideoxy-3 -Thiacytidine((+)- and (--)-SddC) were evaluated for their activities against the human immunodeficiency vs (HIV-1) in cultured H-9 cells. (--)-SddC was six times more inhibitory to HIV-1 and three times less cytotoxic than (+)-SddC. Whereas the intracellular accumulation of the
HIV I infection of dendritic cells.: Int Rev Immunol. 1990;6(2-3):163-75. Unique Identifier : AIDSLINE MED/93210395; Knight SC; Macatonia SE; Patterson S; Medical Research Council, Division of Immunological Medicine,; Clinical Research Centre, Harrow, Middlesex, UK.; Dendritic cells (DC) from human peripheral blood are susceptible to productive and probably to latent infection with HIV-I. Infection of DC also occurs in vivo since in HIV-seropositive individuals Langerhans cells of the skin and DC from peripheral blood, (in preparation) are infected. In peripheral blood 3-25% of D
[Diagnostic value of bronchoalveolar lavage in immunodepressed patients]: Patol Pol. 1990;41(4):178-82. Unique Identifier : AIDSLINE MED/93211738; Marsan C; Chosia M; Zaklad Anatomii i Cytologii Patologicznej Centrum Szpitalnego,; Argenteuil Francja.; Bronchoalveolar lavage, a non invasive study of the function of the lung in cases of interstitial pneumonia, offers remarkable information in immunocompromised patients, particularly as far as the search for pathogens is concerned. The different steps of the technique are reported; the special care of the lavage relat
[Microsporida infections in immunocompetent and immunosuppressed subjects]: Parassitologia. 1991 Dec;33(2-3):209-18. Unique Identifier : AIDSLINE MED/93226416; Croppo GP; Gomez Morales MA; Pozio E; Laboratorio di Parassitologia, Istituto Superiore di Sanita,; Roma, Italia.; Parasites of the phylum Microspora are obligatory intracellular protoza with a widespread host range among invertebrates and vertebrates. Species from Nosema, Encephalitozoon, Enterocytozoon and Pleistophora genera can infect immunocompetent and immunosuppressed patients. The emergency of the AIDS epidemic has recentl
[PAHO. Health in development: 1983-1992]: Bol Oficina Sanit Panam. 1992 Nov-Dec;113(5-6):428-46. Unique Identifier : AIDSLINE MED/93207656
[The campaign against AIDS]: Bol Oficina Sanit Panam. 1992 Nov-Dec;113(5-6):554-7. Unique Identifier : AIDSLINE MED/93207677
[Restructuring can lead to unrest (interview by Siv Barstad)]: J Sykepleien. 1992 Dec 14;80(21):16-7. Unique Identifier : AIDSLINE MED/93207856; Floisands B
[Asia: AIDS--a threat against the country's economy (news)]: J Sykepleien. 1992 Dec 14;80(21):20. Unique Identifier : AIDSLINE MED/93207860
[Bureaucrat with open door (interview by Siv Barstad)]: J Sykepleien. 1992 Dec 14;80(21):36-7. Unique Identifier : AIDSLINE MED/93207866; Dalen M
[The process of adaptation to illness in persons with acquired immunodeficiency syndrome]: Can J Nurs Res. 1992 Fall;24(3):19-35. Unique Identifier : AIDSLINE MED/93208704; Cote JK; Fortin MF; This study was conducted to describe the adaptation process to illness. The study subjects were 50 AIDS patients. The study variables and tools of measurement were chosen according to the Psychosocial Adaptation Model of Craig and Edwards (1983). It was found that throughout the disease process an appraisal-reappraisa
Use of lithium in maintaining T-cell functions in persons with documented acquired immunodeficiency syndrome.: J Natl Med Assoc. 1992 Dec;84(12):1044-6. Unique Identifier : AIDSLINE MED/93210778; Jordan WC; Department of Family Medicine, Charles R. Drew University of; Medicine and Science, Los Angeles, CA 90059.
A breach of trust? [news]: Nurs Times. 1992 Mar 11-17;88(11):19. Unique Identifier : AIDSLINE MED/93211762; de Selincourt K
Hype and prejudice?: Nurs Times. 1992 Mar 11-17;88(11):22. Unique Identifier : AIDSLINE MED/93211763; Faugier J
Kaposi risk from faecal contact [news]: Nurs Times. 1992 Mar 25-31;88(13):10. Unique Identifier : AIDSLINE MED/93211776
[Prevalence of HIV seropositivity in men in consultation for gonococcal urethritis at the STD center of Saint-Louis hospital (letter)]: Presse Med. 1992 Dec 12;21(43):2105. Unique Identifier : AIDSLINE MED/93211853; Lassau F; Casin I; Perenet F; Janier M; Morel P
[Pneumocystis carinii pneumonia in a kidney transplantation center in the proximity of an AIDS care unit (letter)]: Presse Med. 1992 Dec 19-26;21(44):2154. Unique Identifier : AIDSLINE MED/93211870; Glotz D; Kazatchkine M; Vincent F; Haddad H; Duboust A; Druet P; Bariety J
[Specificity in the management of a palliative unit for AIDS patients in the terminal phase]: Rev Infirm. 1992 Dec;42(20):21-3. Unique Identifier : AIDSLINE MED/93212216; Reur M; Comte MF
[1,000,000th copy of the brochure: infection by HIV and AIDS (news)]: Rev Infirm. 1992 Dec;42(20):4. Unique Identifier : AIDSLINE MED/93212221
[AIDS and mortality (news)]: Rev Infirm. 1992 Dec;42(20):5. Unique Identifier : AIDSLINE MED/93212225
[Romania--one year later]: Sygeplejersken. 1992 Jan 2;92(2):23-4. Unique Identifier : AIDSLINE MED/93212363; Rosenberg C
[AIDS: physicians condemned in French hemophiliac scandal]: Sygeplejersken. 1992 Nov 11;92(46):12-3. Unique Identifier : AIDSLINE MED/93212383; Loyau P
[Antibiotic therapy in bronchopulmonary infections]: Ann Ital Med Int. 1992 Jul-Sep;7(3 Suppl):86S-93S. Unique Identifier : AIDSLINE MED/93213669; Moroni M; Franzetti F; Antinori S; Clinica delle Malattie Infettive, Universita degli Studi di; Milano.; Because of difficulties in accurately determining an etiologic diagnosis, the ideal treatment for lower respiratory tract infections remains questionable. Suggested regimens are made on the basis of clinical and epidemiological data. However, the single most common pathogen responsible for pneumonia remains Streptococ
Tonsillar (Waldyer's ring equivalent) lymphoid tissue in the rat: lymphocyte subset binding to high endothelial venules (HEV) and in situ distribution.: Reg Immunol. 1992 Nov-Dec;4(6):401-8. Unique Identifier : AIDSLINE MED/93213712; Koornstra PJ; Duijvestijn AM; Vlek LF; Marres EH; van Breda Vriesman PJ; Department of ENT, Academic Hospital Maastricht, The Netherlands.; We have studied lymphocyte traffic to the Waldeyer s ring equivalent (WRE) lymphoid tissue of the rat, by measuring the in vitro binding of various lymphocyte subsets to high endothelial venules (HEV) in the WRE. In addition, we studied the in situ distribution of these lymphocyte subsets. WRE tissue consists of B and
Suppression of resistance to Giardia muris and cytokine production in a murine model of acquired immune deficiency syndrome.: Reg Immunol. 1992 Nov-Dec;4(6):409-14. Unique Identifier : AIDSLINE MED/93213713; Petro TM; Watson RR; Feely DE; Darban H; University of Nebraska Medical Center, Department of Oral; Biology, Lincoln 68583-0740.; Peyer s patch (PP) T cells through the production of appropriate cytokines foster the development of immunity to the intestinal protozoan parasites such as Giardia. T cell destruction by the human immunodeficiency virus precedes the development of acquired immune deficiency syndrome. Thus, HIV may increase susceptibil
[The impact of AIDS on mortality in Italy]: Epidemiol Prev. 1992 Mar;14(50):29-34. Unique Identifier : AIDSLINE MED/93215786; Conti S; Farchi G; Prati S; Laboratorio di Epidemiologia e Biostatistica, Istituto Superiore; di Sanita, Roma.; Using the official mortality data, collected by ISTAT, and the data of the Italian Register of AIDS cases, in Istituto Superiore di Sanita, three arguments have been developed: 1) Study of causes according to which ISTAT could classify deaths from AIDS: the leading cause appears to be Deficit of Cell Immunity (I.C.D.
T-cell alterations in immunoglobulin A nephropathy.: Int J Clin Pharmacol Res. 1992;12(4):191-5. Unique Identifier : AIDSLINE MED/93216352; Campos A; Rivera F; Egido J; Parera M; Alicante Transfusion Centre, San Juan de Alicante, Spain.; In the present paper are reported alterations of the cellular immunity found in 24 patients with immunoglobulin A nephropathy (IgAN). CD4+ and CD25+ cells were increased in patients in comparison with controls. The mean of interleukin-2 ( IL-2 ) and interleukin-4 (IL-4)
cis and trans regulation of tissue-specific transcription.: J Cell Sci Suppl. 1992;16:21-31. Unique Identifier : AIDSLINE MED/93216854; Engel JD; Beug H; LaVail JH; Zenke MW; Mayo K; Leonard MW; Foley KP; Yang Z; Kornhauser JM; Ko LJ; et al; Department of Biochemistry, Molecular Biology and Cell Biology,; Northwestern University, Evanston, IL 60208-3500.; Analysis of both the cis-regulatory sequences which control globin gene switching as well as the trans-acting factors which bind to these sequences to elicit a differential, developmentally regulated response has lent insight into the general mechanisms responsible for tissue-specific gene regulation. We show here tha
Transmission of SIVMne from female to male Macaca nemestrina.: J Med Primatol. 1992 Aug;21(6):299-307. Unique Identifier : AIDSLINE MED/93217969; Kuller L; Benveniste RE; Watanabe R; Tsai CC; Morton WR; Regional Primate Research Center, University of Washington,; Seattle 98195.; Three SIVMne-infected female pigtailed macaques (Macaca nemestrina) were mated with two SIV-negative males. The females exhibited signs of SAIDS and SIVMne was readily isolated from peripheral blood mononuclear cells (PBMC). Both males became infected with SIVMne, developed SAIDS, and died. This is the first documente
Introduction. Rethinking HIV prevention: critical assessments of the content and delivery of AIDS risk-reduction messages.: Med Anthropol. 1992 May;14(2-4):139-43. Unique Identifier : AIDSLINE MED/93218493; Bolton R; Singer M; Pamona College, Claremont, CA 91711.
AIDS and promiscuity: muddles in the models of HIV prevention.: Med Anthropol. 1992 May;14(2-4):145-223. Unique Identifier : AIDSLINE MED/93218494; Bolton R; Pomona College, Claremont, CA 91711.; AIDS has been blamed on promiscuity and the promiscuous, and a major goal of many HIV-prevention programs has been to induce people to reduce the number of their sexual partners. Despite the salience of this concept in the AIDS discourse of scientists, policymakers, the media, religious leaders, and the gay community,
AIDS, sex and condoms: African healers and the reinvention of tradition in Zaire.: Med Anthropol. 1992 May;14(2-4):225-42. Unique Identifier : AIDSLINE MED/93218495; Schoepf BG; Condoms offer considerable protection against sexual transmission of AIDS. Yet many Africans who are at risk of infection reject condoms as unnatural. Data from Zaire have been used to examine this culturally constructed category in relation to sexuality, procreation, gender roles
HIV prevention: a dramaturgical analysis and practical guide to creating safer sex interventions.: Med Anthropol. 1992 May;14(2-4):243-84. Unique Identifier : AIDSLINE MED/93218496; Taylor CL; Lourea D; Institute For Advanced Study Of Human Sexuality, San Francisco,; CA 94109.; Safer sex is currently a major strategy for preventing HIV transmission. We examine safer sex interventions using an interactionist form of dramaturgical analysis. This approach yields a dynamic model with which to generate novel safer sex interventions highly sensitive to changing individual, cultural, and social var
AIDS and the i.v. drug user: the local context in prevention efforts.: Med Anthropol. 1992 May;14(2-4):285-306. Unique Identifier : AIDSLINE MED/93218497; Singer M; Jia Z; Schensul JJ; Weeks M; Page JB; Hispanic Health Council, Hartford, CT 06106.
Sex, drugs and videotape: the prevention of AIDS in a New York City shelter for homeless men.: Med Anthropol. 1992 May;14(2-4):307-22. Unique Identifier : AIDSLINE MED/93218498; Susser I; Gonzalez MA; Graduate School, City University of New York, NY 10036.; This paper documents a process of social change through participant observation. During the course of research a group response was facilitated by a team of residents, staff and researchers. The social context, a shelter for homeless men in New York City, will be presented first, emphasizing those aspects of resident
Alcohol and risky sex: in search of an elusive connection.: Med Anthropol. 1992 May;14(2-4):323-63. Unique Identifier : AIDSLINE MED/93218499; Bolton R; Vincke J; Mak R; Dennehy E; Pomona College, Claremont, CA 91711.; Since the publication of the 1986 article by Stall, McKusick, Wiley, Coates and Ostrow, the conclusion that drinking alcohol prior to or during erotic encounters increases the probability of engaging in high-risk sexual behavior has been widely accepted, despite some contradictory findings from research on this hypoth
[Psychological reactions of medical staff to the patients infected with HIV-1]: Minerva Psichiatr. 1992 Oct-Dec;33(4):313-6. Unique Identifier : AIDSLINE MED/93218508; Laezza A; Greco D; Raiteri R; Sinicco A; Moniaci D; Universita degli Studi di Torino, USSL 24, Collegno-Grugliasco.; This paper describes the relationship between medical staff and HIV-1 patients. Important mechanisms can be used by individuals with HIV-1 infection in order to accept their seropositivity to HIV-1. Among them, regression and negation are well-known. These mechanisms are related to countertransference lived by the med
Characterization of Bacillus larvae White, the causative agent of American foulbrood of honey-bees. First record of its occurrence in Argentina.: Rev Argent Microbiol. 1992 Apr-Jun;24(2):67-72. Unique Identifier : AIDSLINE MED/93219565; Alippi AM; Catedra de Fitopatologia, Facultad de Agronomia, Universidad; Nacional de La Plata, Argentina.; American foulbrood caused by Bacillus larvae White is recorded for the first time on brood combs of Argentinian hives. The identification of the causative agent was based on disease symptomatology, morphological characters, pathogenicity tests and physiological and biochemical reactions. Studies by scanning electron m
[Molecular analysis of the principal neutralization epitope (V3 loop) of human immunodeficiency virus type 1 in Argentina]: Rev Argent Microbiol. 1992 Apr-Jun;24(2):91-101. Unique Identifier : AIDSLINE MED/93219569; Gomez Carrillo M; Piccardo C; Libonatti O; Departamento de Microbiologia, Facultad de Medicina, Universidad; de Buenos Aires, Argentina.; The main goal of the present paper was to analyze the molecular diversity of the principal neutralizing domain (V3 loop) of the HIV 1 gp120 in samples from patients of Argentina . The study was carried out on a total of 30 HIV 1 positive blood samples, obtained during 1991-1992,
[Estimated biological markers of progression in human immunodeficiency virus infection]: Ann Biol Clin (Paris). 1992;50(9):621-37. Unique Identifier : AIDSLINE MED/93220991; Belec L; Ripoll L; Matta F; Mbopi Keou FX; Cotigny S; Longuet MF; Jacob A; Service de microbiologie (virologie), hopital Broussais, Paris,; France.; The biological markers for determining as early as possible the progression in the infection by the human immunodeficiency virus (HIV) are very important for the health care of patients, and to adapt their anti-retroviral treatment. Among those, four independent biological markers for predicting a pejorative evolution
Ethics--food for thought.: S C Nurse. 1992 Winter;7(4):12-4. Unique Identifier : AIDSLINE MED/93221595; Wessinger MF
A dream come true: one-stop shopping.: S C Nurse. 1992 Winter;7(4):28-9. Unique Identifier : AIDSLINE MED/93221600; Lee EH; Early FD; Silverman K
A proud tradition: the Virginia C. Phillips community health day.: S C Nurse. 1992 Winter;7(4):30. Unique Identifier : AIDSLINE MED/93221601; Greaves P; Hayne B
Public health nurses, points of light.: S C Nurse. 1992 Winter;7(4):31. Unique Identifier : AIDSLINE MED/93221602; Hardee RH
Scientists gear up to fight TB.: Mainlines. 1992 Fall;13(3):8. Unique Identifier : AIDSLINE MED/93222857
Survey on AIDS, fear and infection control: attitudes affecting management decisions.: Clin Prev Dent. 1992 Nov-Dec;14(6):31-4. Unique Identifier : AIDSLINE MED/93223371; Horowitz LG; Lipkowitz RD; As a result of increased public concern about AIDS and dental treatment, dental professionals need to cope with legislative reactions, increased infection control costs, patient anxiety and vigilance on the part of law enforcement agencies regarding compliance with universal precautions. Recommendations abound for edu
Risk factors for HIV infection in gynaecological inpatients in Dar es Salaam, Tanzania, 1988-1990.: East Afr Med J. 1992 Dec;69(12):688-92. Unique Identifier : AIDSLINE MED/93223626; ter Meulen J; Mgaya HN; Chang-Claude J; Luande J; Mtiro H; Mhina M; Kashaija P; Pawlita M; Angewandte Tumorvirologie, Deutsches Krebsforschungszentrum,; Heidelberg, Germany.; A prevalence of 12.8% for anti-HIV-1 and a prevalence of 16.8% for anti-syphilis antibodies was found in 359 gynaecological inpatients admitted in the Department of Gynaecology and Obstetrics, Muhimbili University College of Health Sciences from 1988 to 1990. The highest HIV prevalence (17.3%) was observed in the youn
An analysis of the ethics of health care providers with HIV.: Gen Dent. 1992 Nov-Dec;40(6):460-6. Unique Identifier : AIDSLINE MED/93223989; Chiodo GT; Tolle SW; Center for Ethics in Health Care, Oregon Health Sciences; University, Portland.
Journal of infection control nursing. Sharpening awareness.: Nurs Times. 1992 Apr 1-7;88(14):66-8. Unique Identifier : AIDSLINE MED/93226502; McKeown M
Unconsented HIV tests [news]: Nurs Times. 1992 Apr 1-7;88(14):7. Unique Identifier : AIDSLINE MED/93226503
Substance abuse: the nurse's role in prevention education and caring.: Nurs J India. 1992 May;83(5):130-4. Unique Identifier : AIDSLINE MED/93226509
World AIDS Day 1992 [news]: Nurs J India. 1992 Jun;83(6):154. Unique Identifier : AIDSLINE MED/93226515
[Specific IgA against multiple antigens as expression of immunologic deregulation in HIV-positive children]: Pediatr Med Chir. 1992 Nov-Dec;14(6):583-7. Unique Identifier : AIDSLINE MED/93226524; Rossi ME; Azzari C; Resti M; Carbonella R; Botarelli P; De Martino M; Calabri G; Vierucci A; Clinica Pediatrica III, Universita degli Studi di Firenze,; Italia.; B-cell dysfunction in HIV-infected children is reflected by hypergammaglobulinemia and high levels of serum IgA. Little is known about antibody specificity since only a small portion of serum IgA appears to be directed against HIV proteins. In the present study the specificity of IgA antibodies against food, inhalant,
Fluconazole antifungal agent.: Aust Nurses J. 1992 Oct;22(4):27-8. Unique Identifier : AIDSLINE MED/93228507; Habert M
[Oral hairy leukoplakia in human immunodeficiency virus positive patients: clinical and etiopathogenic aspects]: Acta Otorrinolaringol Esp. 1992 Nov-Dec;43(6):413-7. Unique Identifier : AIDSLINE MED/93229054; Bujia J; Riederer A; Zietz C; Wilmes E; Wolf H; Catedra de Otorrinolaringologia,; Ludwig-Maximilians-Universitat, Munich.; Clinical and etiopathogenetic features of oral hairy leukoplakia in 5 patients positive for Human Immunodeficiency Virus were studied. Oral hairy leukoplakia were located on the lateral borders of the tongue and showed a corrugated/hairy aspect in all the cases. Histological examination showed hyperparakeratosis, acan
[The pulmonary manifestations in AIDS]: Pneumoftiziologia. 1992 Jan-Mar;41(1):21-4. Unique Identifier : AIDSLINE MED/93229949; Marta D; Stoicescu P; Ivan V; Banica D; Bercea O; Institutul de pneumoftiziologie Marius Nasta, Bucuresti.; Clinical and paraclinical experience in HIV infection, though the time elapsed since the first observations is relatively short, begins to get typical outlines. In the case of AIDS, the lung is the main place of opportunistic infections, other inflammatory processes and neoplasia. The present work deals with six clini
Why the treatment with Reprimun could be efficient for tuberculosis prevention in HIV infected individuals.: Pneumoftiziologia. 1992 Jan-Mar;41(1):45-6. Unique Identifier : AIDSLINE MED/93229954; Paunescu E; Marius Nasta Institute of Pneumophthisiology, Depart. of; Immunochemistry and Radioisotopes, Bucharest.
Changes in quality of life among persons with HIV infection.: Qual Life Res. 1992 Dec;1(6):359-66. Unique Identifier : AIDSLINE MED/93230204; Lubeck DP; Fries JF; Department of Medicine, Stanford University, California 94305.; Health-related quality of life (QOL) is an important component of the evaluation of patient outcome in HIV infection where disease is progressive and debilitating. This paper compares patient-reported QOL obtained from questionnaires which cover functional ability, social functioning, cognition, mental health, disabil
Assessing the needs and quality of life of patients with HIV infection: development of the HIV Overview of Problems-Evaluation System (HOPES).: Qual Life Res. 1992 Dec;1(6):397-413. Unique Identifier : AIDSLINE MED/93230208; Schag CA; Ganz PA; Kahn B; Petersen L; Department of Medicine, UCLA School of Medicine.; OBJECTIVE: To develop and evaluate the psychometric properties (reliability, validity etc.) of a comprehensive Quality of Life (QOL) tool, for patients infected with the human immunodeficiency virus (HIV), that was adapted from a previously validated cancer tool. DESIGN: Cross-sectional, patient completed written surv
[Histopathologic study on lymphadenopathy in HIV infected patients]: Chung-hua Ping Li Hsueh Tsa Chih. 1992 Dec;21(6):339-42. Unique Identifier : AIDSLINE MED/93230602; Zhang CH; Department of Pathology, Beijing Friendship Hospital, Capital; Institute of Medicine.; Histopathologic study on the lymphadenopathy of 38 HIV infected patients in Zambia are reported. The histologic type of lymph node changes might be divided as follows: follicular hyperplasia, mixed follicular hyperplasia, follicular involution, and lymphocyte depletion. The author
Immunosuppressive effect induced by Actinobacillus actinomycetemcomitans: effect on immunoglobulin production and lymphokine synthesis.: Oral Microbiol Immunol. 1992 Dec;7(6):338-43. Unique Identifier : AIDSLINE MED/93234094; Kurita-Ochiai T; Ochiai K; Ikeda T; Department of Microbiology, Nihon University School of Dentistry; at Matsudo, Chiba, Japan.; The soluble sonicated extract (SE) from Actinobacillus actinomycetemcomitans inhibited primary T cell-dependent antibody responses in vivo. The production of IgG and IgM to sheep red blood cells (SRBC) was depressed when mice were treated with high concentrations of SE plus SRBC. Preinjection of SE 3 days prior to SRB
[AIDS, management of professional risk and reorganization of nursing care]: Pathol Biol (Paris). 1992 Dec;40(10):980-2. Unique Identifier : AIDSLINE MED/93234132; Bouvet E; Clinique de Reanimation des Maladies Infectieuses, Hopital; Bichat-Claude-Bernard, Paris, France.
[Occupational risk of exposure to blood in nurses. Results of a one-year monitoring of the risk for nurses in 17 hospitals]: Pathol Biol (Paris). 1992 Dec;40(10):983-9. Unique Identifier : AIDSLINE MED/93234133; Abiteboul D; Antona D; Fourrier A; Brucker G; Descamps JM; Leprince A; Pernet M; Bouvet E; GERES (Groupe d'Etudes sur le Risque d'Exposition au Sang),; Vanves, France.; To evaluate the incidence of risk factors for exposure of health care providers to patients blood, a prospective multicenter study was carried out in 1990 in 17 hospitals in continental France . 521 nurses from 20 departments of medicine and 9 intensive care nurses participated in
HIV/AIDS knowledge and awareness of testing and treatment--Behavioral Risk Factor Surveillance System, 1990.: Patient Educ Couns. 1992 Apr;19(2):223-8. Unique Identifier : AIDSLINE MED/93234322
[Knowledge about AIDS among rural workers]: Rev Paul Enferm. 1992 May-Aug;11(2):77-80. Unique Identifier : AIDSLINE MED/93234966; de Oliveira MH; Gir E; Moriya TM; Bueno SM; Borelli O de C; The objective of the present study was to identify the knowledge rural workers have about AIDS in order to develop a specific educational projects. It was observed that part of the population which spontaneously participated in the study presented characteristics of misinformation and alienation about AIDS, as well as
[Drug-induced benign intracranial hypertension. Apropos of a case with amphotericin B. Review of the literature]: Therapie. 1992 Sep-Oct;47(5):403-7. Unique Identifier : AIDSLINE MED/93235168; Heudier P; Chichmanian RM; Taillan B; Gratecos N; Fuzibet JG; Dujardin P; Medecine Interne I, Hopital de Cimiez, Nice.; Benign intracranial hypertension (BICH) is a rare adverse event. We report the case of a 31-year-old female drug addict who had been seropositive for HIV since 1987. She had stage IV C1 AIDS, and was receiving intravenous amphotericin B for generalized cryptococcosis with no neuromeningeal involvement. She developed B
Urocanic acid isomers, immunosuppressive cytokines and the induction of human immunodeficiency virus.: Photodermatol Photoimmunol Photomed. 1992 Jun;9(3):127-30. Unique Identifier : AIDSLINE MED/93237096; Yarosh DB; Alas L; Kibitel JT; Ullrich S; Applied Genetics Inc., Freeport, New York 11520.; The ability of cis-urocanic acid to mimic the effects of ultraviolet (UV) was tested in two systems that show cellular responses to direct UV irradiation. First, cultured mouse keratinocytes were treated with cis-urocanic acid and the cell culture supernatants were injected into mice to test for the ability to block s
[Surveillance of infectious diseases among the persons going abroad through Harbin Port]: Chung Hua Liu Hsing Ping Hsueh Tsa Chih. 1992 Oct;13(5):285-7. Unique Identifier : AIDSLINE MED/93238263; Fu W; Quarantine Service of People's Republic of China Harbin.; This paper reported the results of the health examination of 7447 persons going abroad and 70 persons returning home. The results showed that 349 cases carried HBsAg (with the positive rate 4.7%), and 41 cases with pulmonary tuberculosis (with the positive rate 0.6%), 4 cases with venereal disease (with the positive r
[Therapeutic effect of lymphocytapheresis on patients with HTLV-I-associated myelopathy (HAM)]: Rinsho Shinkeigaku. 1992 Sep;32(9):984-8. Unique Identifier : AIDSLINE MED/93238447; Kubota R; Nakagawa M; Nakamura A; Osame M; Department of Neurology, National Okinawa Hospital.; Lymphocytapheresis (LCP) was performed in 7 patients (1 male and 6 females) with HAM to delete lymphocytes from their peripheral blood, resulting in an improvement of motor disability in 6 of 7 patients with HAM. The therapeutic effect appeared within one day after first LCP, and reached maximum in 2 or 3 sessions of
Decreased suppressor T-lymphocytes in women who received progestogen injections.: J Med Assoc Thai. 1992 Aug;75(8):479-82. Unique Identifier : AIDSLINE MED/93240087; Sridama V; Limpongsanurak S; Sritippayawan S; Youngprapakorn S; Department of Medicine, Faculty of Medicine, Chulalongkorn; University, Bangkok, Thailand.; Decreased levels of suppressor T-cells (CD8+) were found in 17 normal women who received progestogen (Depoprovera) injection, 150 mg intramuscularly every three months for contraceptive purposes, for more than 30 months. The helper: suppressor T-cells (CD4+ : CD8+ ratio) was significantly elevated in this group compar
The biological impact of social responses to the AIDS epidemic.: Med Anthropol. 1992 Nov;15(1):63-79. Unique Identifier : AIDSLINE MED/93240989; McGrath JW; Case Western Reserve University.; This paper examines the extent to which social responses to the AIDS epidemic contribute to the continued transmission of the virus, thereby exacerbating the biological impact of the epidemic. Following the model of McGrath (1991), social responses to AIDS are examined in terms of their impact on potential transmissio
HIV testing in the health care setting: a case review.: Nephrol News Issues. 1992 Oct;6(10):17, 20-1, 25-6. Unique Identifier : AIDSLINE MED/93241345; Bednar B; Peacock E
HIV investigation seemed to be a hoax [letter; comment]: Nephrol News Issues. 1992 Nov;6(11):17. Unique Identifier : AIDSLINE MED/93241351; Keener JK
Nephropathy associated with infection by human immunodeficiency virus: a report on 11 cases including 6 treated with zidovudine.: Nephron. 1992;62(4):434-40. Unique Identifier : AIDSLINE MED/93241425; Michel C; Dosquet P; Ronco P; Mougenot B; Viron B; Mignon F; Service de Nephrologie, Hopital Tenon, Paris, France.; The human immunodeficiency virus (HIV) was recently suggested to be involved in generating kidney lesions in HIV-associated nephropathy (HIVN). The possibility that antiretroviral agents can slow down the usually explosive evolution of HIVN to end-stage renal failure (ESRF) has not been studied in many of the series o
Seroprevalence of antibodies to the human immunodeficiency virus in dialysis workers: results of a multi-center study.: Nephron. 1992;62(4):441-3. Unique Identifier : AIDSLINE MED/93241426; Berlyne G; Kaczmarek RG; Hamburger S; Hamilton P; Moore RM Jr; Charney AN; Kahn T; Gruber M; Kaufman CE; Goffinet J; et al; Department of Veterans Affairs Medical Center, Brooklyn, N.Y.; The Center for Devices and Radiological Health, in collaboration with the Department of Veterans Affairs Medical Center, Brooklyn, N.Y., conducted a multi-center, multi-institutional study of the seroprevalence of antibodies to the human immunodeficiency virus (HIV) among dialysis workers. Seven dialysis units and 112
Transmission groups of French HIV seropositive blood donors (August 1985-December 1990). The French Blood Centers.: Nouv Rev Fr Hematol. 1992;34(6):455-7. Unique Identifier : AIDSLINE MED/93241925; Lefrere JJ; Pillonel J; Institut National de Transfusion Sanguine, Hopital; Saint-Antoine, Paris, France.
Progressive multifocal leukoencephalopathy and gliomas in a HIV-negative patient.: Pathol Res Pract. 1992 Dec;188(8):964-72. Unique Identifier : AIDSLINE MED/93242056; Gullotta F; Masini T; Scarlato G; Kuchelmeister K; Institut fur Neuropathologie, Universitat Munster, FRG.; A case of progressive multifocal leukoencephalopathy (PML) is reported, detected at autopsy of a 30-year-old patient. The clinical picture was characterized by a progressive course of mental deterioration and ingravescent neurological symptoms. The patient was HIV-negative. He died of bronchopneumonia, after a clinica
[India: an expensive and dangerous drug]: Sygeplejersken. 1992 Dec 16;92(51):36-8. Unique Identifier : AIDSLINE MED/93242542; Astrup N
Attempt to eradicate bovine leukemia virus-infected cattle from herds.: Jpn J Vet Res. 1992 Sep;40(2-3):105-11. Unique Identifier : AIDSLINE MED/93211017; Wang CT; Onuma M; Department of Veterinary Medicine, College of Agriculture,; National Taiwan University Taipei, Republic of China.
Incidence of feline immunodeficiency virus reactive antibodies in free-ranging lions of the Kruger National Park and the Etosha National Park in southern Africa detected by recombinant FIV p24 antigen.: Onderstepoort J Vet Res. 1992 Dec;59(4):315-22. Unique Identifier : AIDSLINE MED/93218934; Spencer JA; Van Dijk AA; Horzinek MC; Egberink HF; Bengis RG; Keet DF; Morikawa S; Bishop DH; Department of Infectious Diseases, Faculty of Veterinary Science,; University of Pretoria, Onderstepoort, Republic of South Africa.; Lion sera from the Kruger National Park (KNP) dating back to 1977 and from the Etosha National Park (ENP), obtained from 1989 to 1991, have been analysed by ELISA and Western blot analyses using a genetically engineered antigen representing the p24 structural protein of feline immunodeficiency virus (FIV). It was conc
[AIDS and rheumatic diseases (editorial)]: Chung Hua I Hsueh Tsa Chih (Taipei). 1992 Oct;72(10):579-80. Unique Identifier : AIDSLINE MED/93222999; Jiang M
Publicly funded HIV counseling and testing--United States, 1990.: Patient Educ Couns. 1992 Apr;19(2):219-28. Unique Identifier : AIDSLINE MED/93234321
Favero: strategies to prevent transmission differ for patients, staff [interview]: Nephrol News Issues. 1992 Oct;6(10):11. Unique Identifier : AIDSLINE MED/93241343; Favero MS
Medical judgment versus civil rights, Part II: Or, how illogical!: Nephrol News Issues. 1992 Oct;6(10):11-2, 17, 26. Unique Identifier : AIDSLINE MED/93241344; de Palma J
Cytokines and HIV infection.: Eur Cytokine Netw. 1992 Nov-Dec;3(6):515-21. Unique Identifier : AIDSLINE MED/93208307; Sadat-Sowti B; Debre P; Laboratoire d'immunologie cellulaire et tissulaire, CERVI, Paris,; France.
[World day against AIDS (news)]: Rev Infirm. 1992 Dec;42(20):9. Unique Identifier : AIDSLINE MED/93212226
Pathological status and therapy of HIV-infected hemophiliacs in Japan.: Southeast Asian J Trop Med Public Health. 1992;23 Suppl 2:127-30. Unique Identifier : AIDSLINE MED/93227064; Yamada K; Department of Pediatrics, St Marianna University School of; Medicine, Kawasaki, Japan.; In Japan , 1531 out of 4171 hemophiliacs (36.7%) are human immunodeficiency virus (HIV)-infected, and up to 31 December 1991, 324 (21.2%) of these patients had developed AIDS. The Research Committee estimated the peak of the seroconversion period of hemophiliacs in Japan as January 1
[Excitatory amino-acids, a new class of neurotransmitters. Pharmacology and functional properties]: Encephale. 1992 May-Jun;18(3):271-9. Unique Identifier : AIDSLINE MED/93231085; Krebs MO; The pharmacology of excitatory amino acids (EAA) like glutamate or aspartate, has defined three main types of receptors: NMDA, quisqualate (now named AMPA) and kainate receptors, associated to cationic channels. The NMDA receptor, the best characterized, is a macromolecular complex with multiple specific sites: the ag
Recombinant granulocyte colony-stimulating factor (rG-CSF) in HIV patients with zidovudine related neutropenia.: J Nutr Sci Vitaminol (Tokyo). 1992;Spec No:353-6. Unique Identifier : AIDSLINE MED/93217661; Clumeck N; Wit SD; Hermans P; Franchioly P; Sommereijns B; Division of Infectious Diseases, Saint-Pierre University; Hospital, Brussels, Belgium.
Effects of granulocyte-colony-stimulating factor in neutropenic AIDS-patients.: J Nutr Sci Vitaminol (Tokyo). 1992;Spec No:357-60. Unique Identifier : AIDSLINE MED/93217662; Goebel FD; Bogner JR; Matuschke A; Heinrich B; Kronawitter U; Medizinische Poliklinik, Universitat Munchen, Germany.
[Pneumocystis carinii pneumonia: laboratory diagnosis]: Rev Argent Microbiol. 1992 Apr-Jun;24(2):53-9. Unique Identifier : AIDSLINE MED/93219563; Zdero M; Alvarez V; Ponce de Leon P; Facultad de Ciencias Bioquimicas y Farmaceuticas, Departamento; de Microbiologia, Universidad Nacional de Rosario, Argentina.; We worked with 51 samples, 7 bronchoalveolar lavages (BAL) and 44 sputa (S) of 31 AIDS patients with clinical and radiographic symptoms compatible with Pneumocystis pneumonia. With the aim of finding a specific sensitive methodology for the diagnosis of Pneumocystis carinii, we evaluated 4 coloration techniques (silve
Human immunodeficiency virus in gestational trophoblastic neoplasias--is it a poor prognostic risk factor.: East Afr Med J. 1992 Nov;69(11):647-8. Unique Identifier : AIDSLINE MED/93223615; Ojwang SB; Otieno MR; Khan KS; Department of Obstetric and Gynaecology, Faculty of Medicine,; College of Health Sciences, University of Nairobi, Kenya.; Three cases of HIV infection with choriocarcinoma are presented. One case had prolonged chemotherapy without remission, the second had remission only after combining hysterectomy with chemotherapy and the third who had extensively metastatic disease in the presence of other low risk factors are reported. HIV infection
[Changed levels of substance P and somatostatin in HIV-positive children]: Pediatr Med Chir. 1992 Nov-Dec;14(6):577-81. Unique Identifier : AIDSLINE MED/93226523; Azzari C; Rossi ME; Resti M; Caldini AL; Lega L; Galli L; Fico E; Vierucci A; Clinica Pediatrica III, Universita degli Studi di Firenze,; Italia.; Substance P (sP) and Somatostatin (SOM), so as other neuropeptides can modulate neurologic and immunologic functions. sP has been described to enhance both in vitro and in vivo immunoglobulin synthesis. On the contrary, SOM has an inhibitory effect on the same activity. The modulating effect is more evident on IgA iso
[The inhibitory effects of catechin derivatives on the activities of human immunodeficiency virus reverse transcriptase and DNA polymerases]: Chung Kuo I Hsueh Ko Hsueh Yuan Hsueh Pao. 1992 Oct;14(5):334-8. Unique Identifier : AIDSLINE MED/93230616; Tao P; Institute of Medical Biotechnology, Beijing.; Catechin derivatives including (-)-epicatechin gallate (ECG), (-)-epigallocatechin gallate (EGCG), (-)-epigallocatechin (EGC) and green tea extract (GTE) were found to inhibit the activities of cloned human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT), duck hepatitis B virus replication complexes rev
[Biological actions and therapeutic perspectives of double stranded polyribonucleotides: a reappraisal]: Pathol Biol (Paris). 1992 Dec;40(10):1006-14. Unique Identifier : AIDSLINE MED/93234127; Thang MN; Guschlbauer W; U 245 INSERM, Hopital Saint-Antoine, Paris, France.; Double-stranded polynucleotides, which are composed of two complementary homopolyribonucleotides containing no genetic information, are synthetic molecules capable of mimicking the action of natural double-stranded RNA or viral RNA on cells. Double-stranded polyribonucleotides act as an alarm system alerting the cell
Pathologic quiz case 2. Pneumocystis carinii infection of the external auditory canal.: Arch Otolaryngol Head Neck Surg. 1993 Apr;119(4):466-7, 469. Unique Identifier : AIDSLINE MED/93207715; Henneberry JM; Smith RR; Hruban RH
A PCR-based strategy for extensive mutagenesis of a target DNA sequence.: Biotechniques. 1993 Mar;14(3):454-7. Unique Identifier : AIDSLINE MED/93207780; Morrison HG; Desrosiers RC; New England Regional Primate Research Center, Harvard Medical; School.; A mixed population of mutagenic oligonucleotide primers was used to generate a set of point mutations in a short region of a retroviral gene by PCR amplification. The mixed population of mutagenic primers was generated by incorporating a mixture of A, G, C and T at specific sites during oligonucleotide synthesis. With
Nucleotide sequence analysis of HTLV-I isolated from cerebrospinal fluid of a patient with TSP/HAM: comparison to other HTLV-I isolates.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):109-14. Unique Identifier : AIDSLINE GENBANK/L10341; Mukhopadhyaya R; Sadaie MR; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, MD 20892.; Human T-cell leukemia virus type I (HTLV-I) has been associated with adult T-cell leukemia/lymphoma and the chronic neurologic disorder tropical spastic paraparesis/HTLV-I-associated myelopathy (TSP/HAM). To study the genetic structure of the virus associated with TSP/HAM, we have obtained and sequenced a partial geno
Isolation of a cDNA clone encoding DNA-binding protein (TAXREB107) that binds specifically to domain C of the tax-responsive enhancer element in the long terminal repeat of human T-cell leukemia virus type I.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):115-21. Unique Identifier : AIDSLINE MED/93207816; Morita T; Sato T; Nyunoya H; Tsujimoto A; Takahara J; Irino S; Shimotohno K; Virology Division, National Cancer Center Research Institute,; Tokyo, Japan.; Five cDNA clones for TAXREB proteins that bind to the tax-responsive enhancer element of human T-cell leukemia virus type I (HTLV-I) were isolated from a Jurkat cell cDNA library. The beta-galactosidase fusion proteins of three of these clones specifically recognized the domain C within the enhancer. One of the three
HTLV-II infection in Florida Indians.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):123-7. Unique Identifier : AIDSLINE MED/93207817; Levine PH; Jacobson S; Elliott R; Cavallero A; Colclough G; Dorry C; Stephenson C; Knigge RM; Drummond J; Nishimura M; et al; Viral Epidemiology Branch, National Cancer Institute, National; Institutes of Health, Bethesda, Maryland 20892.; A significantly increased prevalence of antibodies to human T-cell leukemia virus (HTLV) has been described in several native American populations in the United States and Latin America. Initial virologic studies indicate that HTLV-II is the predominant virus responsible for this antib
Simian immunodeficiency virus (mac 251-32H) transmembrane protein sequence remains conserved throughout the course of infection in macaques.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):133-9. Unique Identifier : AIDSLINE MED/93207819; Slade A; Jones S; Almond N; Kitchin P; National Institute for Biological Standards and Control, Potters; Bar, Herts, UK.; Two cynomolgus macaques were infected with a genetically complex challenge stock of simian immunodeficiency virus (SIVmac251-32H). The polymerase chain reaction (PCR) was used to amplify the env gp41, rev, and nef overlapping coding sequences from provirus present in the blood of both animals at 1, 6, and 15 months po
Evaluation of testing algorithms following the use of combination HIV-1/HIV-2 EIA for screening purposes.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):147-51. Unique Identifier : AIDSLINE MED/93207821; Holloman DL; Pau CP; Parekh B; Schable C; Onorato I; Schochetman G; George JR; Division of HIV/AIDS, Centers for Disease Control, Atlanta, GA; 30333.; The licensure of combination human immunodeficiency virus type 1 and type 2 (HIV-1/HIV-2) enzyme immunoassays (EIAs) by the Food and Drug Administration has been accompanied by a recommendation that U.S. blood banks begin testing the nation s blood supply for HIV-2 by June 1, 1992. The performance of a recently licens
Diversification of HIV-1 strains after infection from a unique source.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):153-7. Unique Identifier : AIDSLINE MED/93207822; Kasper P; Kaiser R; Kleim JP; Oldenburg J; Brackmann HH; Rockstroh J; Schneweis KE; Institute of Medical Microbiology and Immunology, University of; Bonn, Germany.; In 1990, 7 hemophilia B patients were infected with human immunodeficiency virus type 1 (HIV-1) after exposure to a single common lot of clotting factor. The hypervariable regions V1 and V2 of the proviral env gene from the patients shared a homology between 97.5% and 100% at the time of seroconversion. To determine t
Effect of mutations in the V3 loop of HIV-1 gp120 on infectivity and susceptibility to proteolytic cleavage.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):159-66. Unique Identifier : AIDSLINE MED/93207823; Schulz TF; Reeves JD; Hoad JG; Tailor C; Stephens P; Clements G; Ortlepp S; Page KA; Moore JP; Weiss RA; Chester Beatty Laboratories, Institute of Cancer Research,; London, UK.; It has been suggested that the V3 domain of human immunodeficiency virus type 1 (HIV-1) isolates has to interact with a cell-surface-associated or endosomal proteinase during virus entry into susceptible cells. To investigate this hypothesis, we examined the effect of several mutations in the V3 loop on its susceptibi
The galactosyl ceramide/sulfatide receptor binding region of HIV-1 gp120 maps to amino acids 206-275.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):175-81. Unique Identifier : AIDSLINE MED/93207825; Bhat S; Mettus RV; Reddy EP; Ugen KE; Srikanthan V; Williams WV; Weiner DB; Department of Neurology, University of Pennsylvania Medical; Center, Philadelphia 19104.; Our recent studies have indicated that galactosyl ceramide (GalCer) or sulfatide (sul) may serve as an alternate receptor for human immunodeficiency virus (HIV) in neural cells. In this paper, we describe the mapping of GalCer/sul binding region of HIV env glycoprotein gp120. Deglycosylated gp120 binds to GalCer, sugg
High levels of 2',5'-oligoadenylate synthetase and 2',5'-oligoadenylate-dependent endonuclease in human trophoblast.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):189-96. Unique Identifier : AIDSLINE MED/93207827; Zhang GY; Beltchev B; Fournier A; Zhang YH; Malassine A; Bisbal C; Ehresmann B; Ehresmann C; Darlix JL; Thang MN; INSERM U. 245, Paris, France.; Human placenta contains a high level of 2 ,5 -oligoadenylate (2-5A) synthetase activity of the 100-kD form of the enzyme. About 20% of the placental 2-5A synthetase activity was found to be cytosolic, whereas the remaining 80% was released by 0.5 M KCl in the presence of detergent. Most of the enzyme activity was loca
Immunological effects of intermediate purity clotting factor concentrates: failure to affect lymphocyte activation in vivo.: Br J Haematol. 1993 Feb;83(2):296-305. Unique Identifier : AIDSLINE MED/93208013; Higgins JA; Giangrande PL; Kernoff PB; Goodall AH; Haemophilia Centre, Royal Free Hospital and School of Medicine,; London.; Concern has been expressed that intermediate purity clotting factor concentrates may cause immunological abnormalities in haemophilic patients, distinct from those related to HIV infection. Early reports of lymphocyte dysfunction in anti-HIV seronegative haemophiliacs pointed to activation of their lymphocytes; a pote
Low-grade thrombotic thrombocytopenic purpura associated with HIV-1 infection.: Br J Haematol. 1993 Feb;83(2):346-7. Unique Identifier : AIDSLINE MED/93208022; Veenstra J; van der Lelie J; Mulder JW; Reiss P; Department of Internal Medicine, University of Amsterdam, The; Netherlands.
A trial of zinc supplementation in young rural Gambian children.: Br J Nutr. 1993 Jan;69(1):243-55. Unique Identifier : AIDSLINE MED/93208073; Bates CJ; Evans PH; Dardenne M; Prentice A; Lunn PG; Northrop-Clewes CA; Hoare S; Cole TJ; Horan SJ; Longman SC; et al; MRC Dunn Nutrition Unit, Cambridge.; The present study tested the hypothesis that inadequate Zn intake might be responsible for failure to thrive and impaired catch-up growth in young rural Gambian children, and that Zn supplements might be beneficial. Gambian children might be deprived of Zn because of its poor availability from their predominantly plan
Interaction of peptide fragment 828-848 of the envelope glycoprotein of human immunodeficiency virus type I with lipid bilayers.: Biochemistry. 1993 Mar 30;32(12):3112-8. Unique Identifier : AIDSLINE MED/93208133; Gawrisch K; Han KH; Yang JS; Bergelson LD; Ferretti JA; Laboratory of Biophysical Chemistry, National Heart, Lung, and; Blood Institute, National Institutes of Health, Bethesda,; Maryland 20892.; The interaction of the peptide fragment 828-848, called P828, from the carboxy-terminal region of the envelope glycoprotein gp41 of HIV-I with model membranes composed of phosphatidylcholine (PC) and phosphatidylglycerol (PG) was investigated using microelectrophoretic mobility of liposomes, fluorescence polarization
Differential interaction of cisplatin with the HIV-1 long terminal repeat in a resistant ovarian carcinoma cell line.: Anticancer Drugs. 1993 Feb;4(1):77-83. Unique Identifier : AIDSLINE MED/93208363; Zoumpourlis V; Kerr DJ; Spandidos DA; Institute of Biological Research and Biotechnology, National; Hellenic Research Foundation, Athens, Greece.; We constructed a recombinant plasmid, pBHIV1, carrying the long terminal repeat (LTR) sequences of HIV-1 linked to the reporter chloramphenicol acetyl transferase (CAT) gene and to the aminoglycoside phosphotransferase (aph) gene as a selectable marker. We have introduced pBHIV1 in a human ovarian cancer cell line A27
Septata intestinalis N. G., N. Sp., an intestinal microsporidian associated with chronic diarrhea and dissemination in AIDS patients.: J Eukaryot Microbiol. 1993 Jan-Feb;40(1):101-12. Unique Identifier : AIDSLINE MED/93208497; Cali A; Kotler DP; Orenstein JM; Department of Biological Sciences, Rutgers University, Newark,; New Jersey 07102.; Intestinal microsporidiosis in patients diagnosed with acquired immunodeficiency syndrome (AIDS) and having chronic diarrhea was first reported in 1985 and the associated microsporidian was named Enterocytozoon bieneusi. The intracellular developmental cycle of E. bien
Are worry-free transfusions just a whiff of ozone away? [news] [published erratum appears in Can Med Assoc J 1993 Jul 15;149(2):145]: Can Med Assoc J. 1993 Apr 1;148(7):1155-60. Unique Identifier : AIDSLINE MED/93208727; Baggs AC
It is ethically defensible to test potential immigrants for HIV, BC committee says [news]: Can Med Assoc J. 1993 Apr 1;148(7):1188. Unique Identifier : AIDSLINE MED/93208732
Declarations concerning AIDS.: Christ Nurse Int. 1993;9(1):11. Unique Identifier : AIDSLINE MED/93208760
Biblical perspectives on AIDS.: Christ Nurse Int. 1993;9(1):12. Unique Identifier : AIDSLINE MED/93208761
Could you be a 'buddy'?: Christ Nurse Int. 1993;9(1):13-5. Unique Identifier : AIDSLINE MED/93208762; Goulding E
Preparing for death--embracing life.: Christ Nurse Int. 1993;9(1):4-5. Unique Identifier : AIDSLINE MED/93208763; Witmer N
HIV and AIDS--a Christian response.: Christ Nurse Int. 1993;9(1):8-10. Unique Identifier : AIDSLINE MED/93208765; Faed J
Breastfeeding. AIDS and other infectious diseases.: Clin Perinatol. 1993 Mar;20(1):225-43. Unique Identifier : AIDSLINE MED/93208980; Goldfarb J; Department of Pediatrics and Adolescent Medicine and Infectious; Diseases, Cleveland Clinic, Ohio.; Breastfeeding has recently been recognized as a mode of transmission of certain important pathogens. It is a major mode of transmission for CMV and HTLV-1. HIV can also be transmitted by breastfeeding, but the relative role of breastfeeding in the epidemiology o
Rationales for treating the human immunodeficiency virus-infected woman during pregnancy.: Clin Perinatol. 1993 Mar;20(1):47-60. Unique Identifier : AIDSLINE MED/93208984; Toltzis P; Case Western Reserve University School of Medicine, Cleveland,; Ohio.; Human immunodeficiency virus (HIV) infection has become one of the leading causes of mortality among American women of childbearing age. Many women will experience a pregnancy after they have been infected. Several rationales exist for offering the pregnant infected woman anti-HIV therapy, including interruption of ve
IDDM in sub-Saharan Africa [letter; comment]: Diabet Med. 1993 Mar;10(2):188. Unique Identifier : AIDSLINE MED/93209017; Swai AB; McLarty DG; Alberti KG
Synergistic activation of the HTLV1 LTR Ets-responsive region by transcription factors Ets1 and Sp1.: EMBO J. 1993 Mar;12(3):1169-78. Unique Identifier : AIDSLINE MED/93209217; Gegonne A; Bosselut R; Bailly RA; Ghysdael J; CNRS-URA 1443, Institut Curie, Section de Biologie, Orsay,; France.; Ets1 is the prototype of a family of transcriptional activators whose activity depends on the binding to specific DNA sequences characterized by an invariant GGA core sequence. We have previously demonstrated that transcriptional activation by Ets1 of the long terminal repeat (LTR) of human T cell lymphotropic virus t
Peptide aldehydes as inhibitors of HIV protease.: FEBS Lett. 1993 Mar 22;319(3):253-6. Unique Identifier : AIDSLINE MED/93209360; Sarubbi E; Seneci PF; Angelastro MR; Peet NP; Denaro M; Islam K; Lepetit Research Center, MMDRI, Gerenzano, VA, Italy.; We have recently shown that alpha-MAPI, a peptidic aldehyde of microbial origin, inhibits the HIV protease with a potency comparable to pepstatin, having, differently from pepstatin, no activity on other aspartic proteases. In this study different peptide derivatives containing a C-terminal aldehyde have been tested t
Collecting data to evaluate the effect of health policies on vulnerable populations.: Fam Med. 1993 Feb;25(2):114-9. Unique Identifier : AIDSLINE MED/93209498; Bindman AB; Grumbach K; Keane D; Lurie N; Division of General Internal Medicine, San Francisco General; Hospital.; Public health policies often have disproportionate effects on the poor and other vulnerable groups. Standard survey techniques are often difficult to apply to these vulnerable populations, and many data bases systematically omit such individuals. The purpose of this paper is to review our experience in collecting prim
Appeals court: HIV-infected surgeons can be liable for not informing patients ... Rossi v. Almarez [news]: Hospitals. 1993 Apr 5;67(7):12. Unique Identifier : AIDSLINE MED/93209639
Learning from experience. In AIDS treatment, knowledge means quality.: Hospitals. 1993 Apr 5;67(7):32-5. Unique Identifier : AIDSLINE MED/93209644; Sandrick K; Recent clinical studies have revealed startling differences in mortality for AIDS patients in low- versus high-experience hospitals. But how can low-experience hospitals learn from high-experience ones?
Clinical experience with Escherichia coli rHuGM-CSF.: Int Rev Exp Pathol. 1993;34 Pt B:209-16. Unique Identifier : AIDSLINE MED/93209784; Stern AC; Jones TC; Sandoz Pharma Ltd., Basel, Switzerland.; The use of rHuGM-CSF has resulted in patient benefit as shown by reduced infections (MDS and AA), reduced days in intensive care (ABM transplant), better adherence to cancer chemotherapy protocols, and the ability to use full doses of antiviral drugs in AIDS and cytomegalovirus ret
Enzyme immunoassay for detection of human immunodeficiency virus-specific immunoglobulin A antibodies.: J Clin Microbiol. 1993 Mar;31(3):681-4. Unique Identifier : AIDSLINE MED/93210097; Connor E; Wang Z; Stephens R; Holland B; Palumbo P; McSherry G; Oleske J; Denny T; Department of Pediatrics, UMD-New Jersey Medical School, Newark; 07103.; Early diagnosis of human immunodeficiency virus (HIV) infection may be difficult in adults with acute or recent HIV infection and in infants with perinatally acquired HIV. Detection of HIV-specific immunoglobulin A (IgA) antibodies in infant serum by Western blot (immunoblot) has been suggested as a reliable method to
Endocarditis caused by Rochalimaea quintana in a patient infected with human immunodeficiency virus.: J Clin Microbiol. 1993 Mar;31(3):692-4. Unique Identifier : AIDSLINE MED/93210100; Spach DH; Callis KP; Paauw DS; Houze YB; Schoenknecht FD; Welch DF; Rosen H; Brenner DJ; Department of Medicine, University of Washington School of; Medicine, Seattle.; Rochalimaea quintana and Rochalimaea henselae are closely related, fastidious, gram-negative rickettsiae. Thus far, the spectrum of human Rochalimaea sp. infections has not included endocarditis. We describe a 50-year-old human immunodeficiency virus-positive man who developed endocarditis caused by R. quintana. DNA r
Use of the UV ParaLens adapter as an alternative to conventional fluorescence microscopy for detection of Pneumocystis carinii in direct immunofluorescent monoclonal antibody-stained pulmonary specimens.: J Clin Microbiol. 1993 Mar;31(3):720-1. Unique Identifier : AIDSLINE MED/93210108; Mattia AR; Waldron MA; Sierra LS; Department of Pathology, Massachusetts General Hospital, Boston; 02114.; The UV ParaLens light microscope adapter offers a useful and cost-effective alternative to conventional fluorescence microscopy for Pneumocystis carinii identification, particularly in AIDS patients. In a blinded study, in which 153 pulmonary specimens were examined for P. carinii by direct immunofluorescence, 40 of 4
Comparison of enterotoxin production, cytotoxin production, serogrouping, and antimicrobial susceptibilities of Clostridium difficile strains isolated from AIDS and human immunodeficiency virus-negative patients.: J Clin Microbiol. 1993 Mar;31(3):740-2. Unique Identifier : AIDSLINE MED/93210116; Barbut F; Depitre C; Delmee M; Corthier G; Petit JC; Department of Microbiology, Saint-Antoine Hospital, Paris 12,; France.; We analyzed and compared Clostridium difficile strains isolated from diarrheic stools of 49 human immunodeficiency virus (HIV)-negative and 50 AIDS patients. Our results suggest that distribution patterns of serogroups are different in these two populations. Serogroup C (which has been previously reported to be very r
Stability of human immunodeficiency virus type 1 antibodies in whole blood-impregnated filter papers under various tropical conditions [letter; comment]: J Clin Microbiol. 1993 Mar;31(3):765-6. Unique Identifier : AIDSLINE MED/93210125; Arya SC
HIV gp120 alteration of DAMA and IL-1 alpha induced chemotaxic responses in human and invertebrate immunocytes.: J Neuroimmunol. 1993 Mar;43(1-2):177-84. Unique Identifier : AIDSLINE MED/93210137; Stefano GB; Smith EM; Cadet P; Hughes TK Jr; Old Westbury Neuroscience Institute, State University of New York; 11568.; The effects of a synthetic peptide fragment of human immunodeficiency virus gp120 (HIV gp120) on opioid (D-ala2-D-met5 enkephalinamide; DAMA) and interleukin-1 (IL-1) induced chemotactic responses in human granulocytes and monocytes and invertebrate (Mytilus edulis) immunocytes were studied. Both DAMA and IL-1 increas
Quantitative and qualitative comparison of DNA amplification by PCR with immunofluorescence staining for diagnosis of Pneumocystis carinii pneumonia.: J Clin Pathol. 1993 Feb;46(2):140-4. Unique Identifier : AIDSLINE MED/93210200; Leigh TR; Gazzard BG; Rowbottom A; Collins JV; Department of Respiratory Medicine, Westminster Hospital, London.; AIM: To compare the results of DNA amplification by the polymerase chain reaction (PCR) with immunofluorescence staining for detecting Pneumocystis carinii in bronchoalveolar lavage specimens taken from symptomatic HIV seropositive patients with suspected P carinii pneumonia (PCP). METHODS: Bronchoalveolar lavage spec
Inactivation of HIV-infected H9 cells in whole blood preparations by lysing/fixing reagents used in flow cytometry.: J Immunol Methods. 1993 Apr 2;160(2):215-8. Unique Identifier : AIDSLINE MED/93210316; Nicholson JK; Browning SW; Orloff SL; McDougal JS; Immunology Branch, Centers for Disease Control, Atlanta, GA; 30333.; Reagents that lyse red blood cells and fix white blood cells were tested for their ability to inactivate cell-associated human immunodeficiency virus (HIV). Whole blood was spiked with cells from an HIV-positive cell line (H9), lysed, and fixed. The cell preparations were then cocultured with T cell blasts in serial t
Clinical implications of HIV seroprevalence in childbearing women: the Louisiana experience.: J La State Med Soc. 1993 Mar;145(3):92-4, 97-9. Unique Identifier : AIDSLINE MED/93210406; Longfellow L; Troxler S; Michael G; Beltrami JF; Dal Corso M; McFarland L; Van Dyke R; Office of Public Health, State of Louisiana, New Orleans.; An epidemiologic analysis of the HIV Seroprevalence Survey of Childbearing Women in Louisiana and the Louisiana AIDS Surveillance Report was conducted to inform health care practitioners of the trends in HIV infection and AIDS cases in women and children. HIV seropositivity in childbearing women has increased by 64% f
Lethal exacerbation of Pneumocystis carinii pneumonia in severe combined immunodeficiency mice after infection by pneumonia virus of mice.: J Exp Med. 1993 Apr 1;177(4):1193-8. Unique Identifier : AIDSLINE MED/93210475; Roths JB; Smith AL; Sidman CL; Department of Molecular Genetics, Biochemistry and Microbiology,; University of Cincinnati College of Medicine, Ohio 45267-0524.; Mice homozygous for the mutant allele scid (severe combined immunodeficiency) have been described as excellent models for Pneumocystis carinii (Pc) pneumonia (PCP), a major health problem in patients with acquired immune deficiency syndrome (AIDS) and other immunodeficiency states. Other microorganisms have been shown
A rat CD4 mutant containing the gp120-binding site mediates human immunodeficiency virus type 1 infection.: J Exp Med. 1993 Apr 1;177(4):949-54. Unique Identifier : AIDSLINE MED/93210489; Simon JH; Somoza C; Schockmel GA; Collin M; Davis SJ; Williams AF; James W; Sir William Dunn School of Pathology, University of Oxford,; United Kingdom.; CD4 is the primary receptor for the human immunodeficiency virus type 1 (HIV-1). Early mutational studies implicated a number of residues of CD4, centered in the region 41-59, in binding to gp120. However, further mutational analyses, together with studies using inhibitory antibodies or CD4-derived peptides, have sugg
Photosensitizers as virucidal agents.: J Photochem Photobiol B. 1993 Feb;17(2):99-108. Unique Identifier : AIDSLINE MED/93210606; North J; Neyndorff H; Levy JG; Quadra Logic Technologies Inc., Vancouver, BC, Canada.; The photosensitizer, benzoporphyrin derivative monoacid ring A (BPD-MA) has been studied regarding its ability to destroy enveloped viruses in blood and blood products when activated by light. Its maximum wavelength of absorption (690 nm) has proven useful in terms of activation of the photosensitizer in materials con
Prevalence of HIV infection and AIDS in Egypt over four years of surveillance (1986-1990).: J Trop Med Hyg. 1993 Apr;96(2):113-7. Unique Identifier : AIDSLINE MED/93210814; Watts DM; Constantine NT; Sheba MF; Kamal M; Callahan JD; Kilpatrick ME; US Naval Medical Research Unit No. 3, Cairo, Egypt.; Serosurveys were conducted from April 1986 to March 1990 to determine the prevalence of HIV-1 infections among Egyptians and foreigners. Sera from 29,261 high risk individuals and blood or blood product donors in Egypt, and from 10,326 foreigners were tested for HIV-1 antibodies by a recombinant HIV-1 and a recombinan
Increasing risk of transfusion-associated AIDS as the pandemic spreads: experience in Maiduguri, Nigeria.: J Trop Med Hyg. 1993 Apr;96(2):131-3. Unique Identifier : AIDSLINE MED/93210818; Harry TO; Moses AE; Ola TO; Obi SO; Bajani MD; University of Maiduguri Teaching Hospital, Borno State, Nigeria.; Complacency and financial considerations have led many hospitals in developing countries with low HIV antibody prevalence to disregard the importance of pre-screening for HIV antibodies blood meant for transfusion. This report shows that during the year 1987 in which mandatory screening of donated blood was introduced
Investigation of potential HIV transmission to the patients of an HIV-infected surgeon [see comments]: JAMA. 1993 Apr 14;269(14):1795-801. Unique Identifier : AIDSLINE MED/93210848; Rogers AS; Froggatt JW 3d; Townsend T; Gordon T; Brown AJ; Holmes EC; Zhang LQ; Moses H 3d; AIDS Administration, Maryland State Department of Health and; Mental Hygiene, Baltimore.; OBJECTIVE--To ascertain if a surgeon infected with the human immunodeficiency virus (HIV) transmitted HIV to patients during invasive surgical procedures. DESIGN--Survey of patients and acquired immunodeficiency syndrome (AIDS) case registries, and laboratory analysis of nucleotide sequence data. SETTING--One surgeon
Absence of HIV transmission from an infected dentist to his patients. An epidemiologic and DNA sequence analysis [see comments]: JAMA. 1993 Apr 14;269(14):1802-6. Unique Identifier : AIDSLINE MED/93210849; Dickinson GM; Morhart RE; Klimas NG; Bandea CI; Laracuente JM; Bisno AL; Medical Service, VA Medical Center, Miami, FL 33125.; OBJECTIVE--To determine if a general dentist with human immunodeficiency virus (HIV) infection transmitted HIV to any of his patients. DESIGN--A cohort study in which all patients treated by a dentist who developed the acquired immunodeficiency syndrome (AIDS) were identified and attempts were made to contact all pati
Absence of HIV transmission from an infected orthopedic surgeon. A 13-year look-back study [published erratum appears in JAMA 1993 Aug 4;270(5):579] [see comments]: JAMA. 1993 Apr 14;269(14):1807-11. Unique Identifier : AIDSLINE MED/93210850; von Reyn CF; Gilbert TT; Shaw FE Jr; Parsonnet KC; Abramson JE; Smith MG; Department of Medicine, Dartmouth-Hitchcock Medical Center,; Lebanon, NH 03756.; OBJECTIVE--To determine the risk of human immunodeficiency virus (HIV) transmission from an HIV-infected orthopedic surgeon to patients undergoing invasive procedures. DESIGN--Retrospective epidemiologic follow-up study. PARTICIPANTS--A total of 2317 former patients on whom the orthopedic surgeon performed invasive pr
HIV-infected surgeons and dentists. Looking back and looking forward [editorial; comment] [see comments]: JAMA. 1993 Apr 14;269(14):1843-4. Unique Identifier : AIDSLINE MED/93210857; Mishu B; Schaffner W
[Acquired immunodeficiency syndrome (AIDS)]: Nippon Rinsho. 1993 Jan;51 Suppl:643-8. Unique Identifier : AIDSLINE MED/93210944; Shiokawa Y; Juntendo University.
Canada decides, at last, to increase spending on AIDS [news]: Nature. 1993 Mar 18;362(6417):199. Unique Identifier : AIDSLINE MED/93211465; Spurgeon D
Care of the HIV-infected woman should have a holistic focus [letter; comment]: Nurse Pract. 1993 Mar;18(3):11. Unique Identifier : AIDSLINE MED/93211581; DeRemer P
A clinician's view of the HIV question.: N Y State Dent J. 1993 Mar;59(3):39-42. Unique Identifier : AIDSLINE MED/93211597; Glick M; Infectious Disease Center, Temple University School of Dentistry.
AIDS information resource [letter]: Postgrad Med. 1993 Apr;93(5):44. Unique Identifier : AIDSLINE MED/93211843; Darga RJ
Theoretical studies of relaxation of a monomeric subunit of HIV-1 protease in water using molecular dynamics.: Proteins. 1993 Apr;15(4):374-84. Unique Identifier : AIDSLINE MED/93211902; Venable RM; Brooks BR; Carson FW; Biophysics Laboratory, Center for Biologics Evaluation and; Research, Food and Drug Administration, Bethesda, Maryland 20892.; The dynamic behavior of one 99-residue subunit of the dimeric aspartyl protease of HIV-1 was studied in a 160 psec molecular dynamics simulation at 300 K in water. The crystal structure of one of the identical subunits of the dimer was the starting point, with the aqueous phase modeled by 4,331 explicit waters in a re
Different AIDS incubation periods and their impacts on reconstructing human immunodeficiency virus epidemics and projecting AIDS incidence.: Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2194-6. Unique Identifier : AIDSLINE MED/93211928; Bacchetti P; Segal MR; Hessol NA; Jewell NP; Department of Epidemiology and Biostatistics, University of; California, San Francisco 94143-1347.; The objective of this study was to investigate heterogeneity in incubation distributions in different cohorts and to assess the sensitivity of back-calculated infection rates to different assumptions about incubation times from human immunodeficiency virus (HIV) infection to AIDS diagnosis. Incubation distributions we
Ontogeny of anti-human immunodeficiency virus (HIV) antibody production in HIV-1-infected infants.: Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2340-4. Unique Identifier : AIDSLINE MED/93211957; Pollack H; Zhan MX; Ilmet-Moore T; Ajuang-Simbiri K; Krasinski K; Borkowsky W; Department of Pediatrics, New York University Medical Center, NY.; The early serologic response of infants to infection with human immunodeficiency virus type 1 (HIV-1) is normally obscured by the presence of transplacentally acquired maternal HIV antibody. By measuring HIV antibody produced in vitro by lymphocytes isolated from peripheral blood of infants and children of HIV-1-infec
Inhibitors of human immunodeficiency virus integrase.: Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2399-403. Unique Identifier : AIDSLINE MED/93211969; Fesen MR; Kohn KW; Leteurtre F; Pommier Y; Laboratory of Molecular Pharmacology, National Cancer Institute,; Bethesda, MD 20892.; In an effort to further extend the number of targets for development of antiretroviral agents, we have used an in vitro integrase assay to investigate a variety of chemicals, including topoisomerase inhibitors, antimalarial agents, DNA binders, naphthoquinones, the flavone quercetin, and caffeic acid phenethyl ester a
Resistance to human immunodeficiency virus 1 infection of SCID mice reconstituted with peripheral blood leukocytes from donors vaccinated with vaccinia gp160 and recombinant gp160.: Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2443-7. Unique Identifier : AIDSLINE MED/93211978; Mosier DE; Gulizia RJ; MacIsaac PD; Corey L; Greenberg PD; Division of Immunology, Medical Biology Institute, La Jolla, CA; 92037.; SCID mice reconstituted with adult human peripheral blood leukocytes (hu-PBL-SCID mice) make antigen-specific human antibody responses following secondary immunization and can be infected with human immunodeficiency virus 1 (HIV-1), suggesting that they might prove useful for evaluating protective immunity to HIV-1 fo
[A tuberculotic subcutaneous abscess as the form of presentation of the acquired immunodeficiency syndrome (letter)]: Rev Clin Esp. 1993 Feb;192(2):95-6. Unique Identifier : AIDSLINE MED/93212118; Mellado B; Pedrol E; Casademont J; Grau JM
[Management of patients with HIV: a nurse witness (interview by Isabelle Lefevre)]: Rev Infirm. 1993 Jan;43(2):12-6. Unique Identifier : AIDSLINE MED/93212234; Genvresse C
[Infection by HIV]: Rev Infirm. 1993 Jan;43(2):21-7. Unique Identifier : AIDSLINE MED/93212235
[Professional risk of infection by the human immunodeficiency virus]: Rev Infirm. 1993 Jan;43(2):28-33. Unique Identifier : AIDSLINE MED/93212236; Leprince A; Bouvet E; Abiteboul D
[Risks of AIDS transmission in the surgical milieu]: Rev Infirm. 1993 Jan;43(2):34-6. Unique Identifier : AIDSLINE MED/93212237; Dufour G
[Digestive infections during AIDS, experience in Lyons with 81 patients]: Rev Infirm. 1993 Jan;43(2):38-40. Unique Identifier : AIDSLINE MED/93212239; Cotte L; Rabodonirina M; Drouet E; Gelas P; Trepo C
[Information on AIDS in industries]: Rev Infirm. 1993 Jan;43(2):41-6. Unique Identifier : AIDSLINE MED/93212240
[The contribution of Public Assistance--Hospitals of Paris to the campaign against AIDS]: Rev Infirm. 1993 Jan;43(2):47-9. Unique Identifier : AIDSLINE MED/93212241
[Action of the cultural minister in the campaign against AIDS]: Rev Infirm. 1993 Jan;43(2):50-1. Unique Identifier : AIDSLINE MED/93212242
[Dossier: AIDS. Organizations and associations]: Rev Infirm. 1993 Jan;43(2):52-5. Unique Identifier : AIDSLINE MED/93212243
[Financing of AIDS prevention: serious warning from WHO (news)]: Rev Infirm. 1993 Jan;43(2):6. Unique Identifier : AIDSLINE MED/93212247
Interferon alpha-2b treatment in an HIV-infected patient with hepatitis B virus induced nephrotic syndrome.: Scand J Infect Dis. 1993;25(1):133-5. Unique Identifier : AIDSLINE MED/93212267; Lidman C; Magnius L; Norder H; Weiland O; Department of Infectious Diseases, Huddinge Hospital, Karolinska; Institute, Stockholm, Sweden.; A 31-year-old male patient with an asymptomatic HIV infection but with a hepatitis B (HBV) related membraneous glomerulonephritis with nephrotic syndrome was given interferon alpha-2b subcutaneously 3 times weekly for 7.5 months. Zidovudine was added at the 10th week due to low CD4+ cell counts. Before the 6th week of
Doxycycline and pyrimethamine for toxoplasmic encephalitis.: Scand J Infect Dis. 1993;25(1):157-60. Unique Identifier : AIDSLINE MED/93212273; Hagberg L; Palmertz B; Lindberg J; Department of Infectious Diseases, Ostra Hospital, University of; Goteborg, Sweden.; Clinical improvement is reported in a 40-year-old man with AIDS and presumed toxoplasmic encephalitis, who was treated with doxycycline, 400 mg, and pyrimethamine, 25 mg, daily. Computerised tomography (CT) scanning of the brain showed complete resolution of 2 ring-enhanced lesions within 5 weeks.
Prevalence of hepatitis B virus markers among intravenous drug abusers in Stockholm: impact of heterosexual transmission.: Scand J Infect Dis. 1993;25(1):8-13. Unique Identifier : AIDSLINE MED/93212285; Struve J; Kall K; Stendahl P; Scalia-Tomba G; Giesecke J; Weiland O; Department of Infectious Diseases, Karolinska Institute, Huddinge; Hospital, Sweden.; In order to study the importance of sexual transmission of hepatitis B virus (HBV) among intravenous drug abusers (IVDAs), and from IVDAs to others, we consecutively interviewed 171 IVDAs detained at the Stockholm Remand Prison during 4 months in 1990. Sexual histories revealed that 77% reported > or = 3 sexual partne
Long-term noncytopathic productive infection of the human monocytic leukemia cell line THP-1 by human immunodeficiency virus type 1 (HIV-1IIIB).: Virology. 1993 Apr;193(2):877-87. Unique Identifier : AIDSLINE MED/93212521; Konopka K; Pretzer E; Plowman B; Duzgunes N; Department of Microbiology, University of the Pacific, School of; Dentistry, San Francisco, California 94115.; A long-term, noncytopathic, productive infection of the monocytic leukemia cell line THP-1 with human immunodeficiency virus type 1 (HIV-1IIIB) was established. Both infected cells (THP-1/HIV-1IIIB) growing in suspension and uninfected, phorbol 12-myristate 13-acetate (PMA)-treated THP-1 cells, which are adherent, sho
Identification of a region in the Pr55gag-polyprotein essential for HIV-1 particle formation.: Virology. 1993 Apr;193(2):981-5. Unique Identifier : AIDSLINE MED/93212534; von Poblotzki A; Wagner R; Niedrig M; Wanner G; Wolf H; Modrow S; Institut fur medizinische Mikrobiologie und Hygiene,; Universitat Regensburg, Germany.; The pr55gag polyprotein of HIV-1 plays a critical role in the formation of immature virus particles in the cell and during the budding process. We investigated the influence of amino acid substitutions in the p24CA- region of the gag polyprotein on the viral assembly process. Deletion of the amino acids 341-352 in the
Neurosurgical management of the acquired immunodeficiency syndrome. An update.: West J Med. 1993 Mar;158(3):249-53. Unique Identifier : AIDSLINE MED/93212555; Andrews BT; Kenefick TP; Department of Neurosurgery, California Pacific Medical Center,; San Francisco.; A retrospective review of a 24-month experience on the neurosurgical service at a large metropolitan hospital identified 33 patients with the acquired immunodeficiency syndrome (AIDS) who underwent diagnostic or therapeutic procedures. Intracranial mass lesions unresponsive to empiric medical therapy for presumed Toxo
Acquired immunodeficiency syndrome vaccines.: West J Med. 1993 Mar;158(3):296-7. Unique Identifier : AIDSLINE MED/93212564; Gardner MB
Enhancing antibody and its role in acquired immunodeficiency syndrome.: West J Med. 1993 Mar;158(3):297-8. Unique Identifier : AIDSLINE MED/93212566; Robinson WE Jr
AIDS--science, medicine, and metaphor [editorial]: West J Med. 1993 Mar;158(3):304-7. Unique Identifier : AIDSLINE MED/93212571; Osborn JE
Tumor necrosis factor-alpha induces circular forms of human immunodeficiency virus type-1 DNA in the persistently infected low-level expressing cell line, ACH-2.: Virus Res. 1993 Feb;27(2):113-8. Unique Identifier : AIDSLINE MED/93212586; Kitamura K; Zaki SR; Greer PW; Sinha SD; Folks TM; Retrovirus Disease Branch, Centers for Disease Control, Atlanta,; GA 30333.; The low human immunodeficiency virus type-1 (HIV-1) expressing T-cell line, ACH-2, was used to investigate accumulation of the circular, extrachromosomal form of HIV DNA (HD) after tumor necrosis factor-alpha (TNF-alpha) induction. We chose the 2 long terminal repeat (LTR) circular form to analyze unintegrated HD by p
Recent advances in breast feeding.: Acta Paediatr Jpn. 1993 Feb;35(1):1-12. Unique Identifier : AIDSLINE MED/93212615; Woolridge MW; Phil D; Baum JD; Institute of Child Health, University of Bristol, Royal Hospital; for Sick Children, St Michael's Hill, United Kingdom.; Increasingly, epidemiological studies are showing the benefits of exclusive breast-feeding to infants in industrialized countries, as they have previously for those in developing countries. In this review we have focused on several recent developments, in particular on the interplay between infant behaviour and matern
Two color flow cytometric analysis of lymphocytes in HTLV-I carrier children.: Acta Paediatr Jpn. 1993 Feb;35(1):13-6. Unique Identifier : AIDSLINE MED/93212616; Sato T; Yanagisawa M; Muchi H; Department of Pediatrics, Jichi Medical School, Tochigi, Japan.; Phenotypic changes in lymphocytes from healthy children with antibody for human T lymphotrophic virus type I (HTLV-I) were studied using two color flow cytometry. The subjects were high school students within a small district of Kyushu, Japan . In the carrier group, a subset of lymph
Growth and body composition in children infected with the human immunodeficiency virus-1.: Am J Clin Nutr. 1993 Apr;57(4):588-92. Unique Identifier : AIDSLINE MED/93212705; Miller TL; Evans SJ; Orav EJ; Morris V; McIntosh K; Winter HS; Combined Program in Pediatric Gastroenterology and Nutrition,; Children's Hospital, Boston, MA 02115.; Anthropometric data were collected on 89 children born to human immunodeficiency virus (HIV)-infected women (37 who seroreverted and 52 who were HIV-infected). The main outcomes included birth weight, gestational age, weight, height, arm muscle circumference (AMC), and triceps skinfold thickness (TSF). Gestational age
Getting real about HIV in adolescents [editorial; comment] [see comments]: Am J Public Health. 1993 Apr;83(4):492-4. Unique Identifier : AIDSLINE MED/93212856; Hein K
The ethics of blinded HIV surveillance testing [comment]: Am J Public Health. 1993 Apr;83(4):496-7. Unique Identifier : AIDSLINE MED/93212858; Bayer R; Columbia University, School of Public Health, New York, NY 10032.
Commentary: the new female condom--item 1 on a women's AIDS prevention agenda.: Am J Public Health. 1993 Apr;83(4):498-500. Unique Identifier : AIDSLINE MED/93212859; Gollub EL; Stein ZA; HIV Center for Clinical and Behavioral Studies, New York State; Psychiatric Institute, Columbia University, NY 10032.; A US Food and Drug Administration ( FDA ) advisory panel has recommended that the female condom Reality be approved for contraception and acquired immunodeficiency syndrome (AIDS) prevention. Final FDA approval will mark the first official recognition of a woman-controlled method for pr
Commentary: condoms and HIV/STD prevention--clarifying the message [see comments]: Am J Public Health. 1993 Apr;83(4):501-3. Unique Identifier : AIDSLINE MED/93212860; Roper WL; Peterson HB; Curran JW; Centers for Disease Control and Prevention, Atlanta, Ga. 30333.; In the United States and throughout the world, the majority of human immunodeficiency virus (HIV) infections are sexually transmitted. an estimated 12 million other sexually transmitted diseases occur annually in the United States. Avoiding sexual intercourse altogether or restricting
Sentinel surveillance for HIV-2 infection in high-risk US populations.: Am J Public Health. 1993 Apr;83(4):515-9. Unique Identifier : AIDSLINE MED/93212863; Onorato IM; O'Brien TR; Schable CA; Spruill C; Holmberg SD; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, GA 30333.; OBJECTIVES. We conducted sentinel surveillance in persons practicing behaviors known to transmit retroviruses to determine the US presence and extent of human immunodeficiency virus type 2 (HIV-2). METHODS. Sentinel surveillance for HIV-2 was conducted by testing 31,533 anonymous blood specimens from patients at sexua
American adults' knowledge of HIV testing availability [see comments]: Am J Public Health. 1993 Apr;83(4):525-8. Unique Identifier : AIDSLINE MED/93212865; Valdiserri RO; Holtgrave DR; Brackbill RM; National Center for Prevention Services, Centers for Disease; Control and Prevention, Atlanta, Ga. 30333.; OBJECTIVES. Understanding client needs, knowledge, and preferences about services is necessary to ensure that human immunodeficiency virus (HIV) counseling and testing programs are accessible. This study addressed knowledge of HIV testing availability. METHODS. To study American adults knowledge of HIV testing availa
Changes in sexually transmitted disease rates after HIV testing and posttest counseling, Miami, 1988 to 1989 [see comments]: Am J Public Health. 1993 Apr;83(4):529-33. Unique Identifier : AIDSLINE MED/93212866; Otten MW Jr; Zaidi AA; Wroten JE; Witte JJ; Peterman TA; Division of STD/HIV Prevention, Centers for Disease Control and; Prevention, Atlanta, Ga. 30333.; OBJECTIVES. The effects of posttest counseling on acquisition of sexually transmitted diseases in patients at a large urban sexually transmitted disease clinic were studied. METHODS. Comparisons were made of the percentage of patients who had a positive gonorrhea culture (or any sexually transmitted disease) in the 6
Depressive symptoms in blood donors notified of HIV infection.: Am J Public Health. 1993 Apr;83(4):534-9. Unique Identifier : AIDSLINE MED/93212867; Cleary PD; Van Devanter N; Rogers TF; Singer E; Shipton-Levy R; Steilen M; Stuart A; Avorn J; Pindyck J; Department of Health Care Policy, Harvard Medical School, Boston,; Mass. 02115.; OBJECTIVES. Understanding more about the psychological state of persons notified of human immunodeficiency virus (HIV) infection is critical for designing notification and counseling programs that will have the most positive effect. METHODS. The subjects were blood donors who had been notified of HIV infection by the
Prevalence of HIV infection among psychiatric patients in a New York City men's shelter.: Am J Public Health. 1993 Apr;83(4):568-70. Unique Identifier : AIDSLINE MED/93212873; Susser E; Valencia E; Conover S; Columbia University Department of Psychiatry, New York, NY.; We report on the prevalence of human immunodeficiency virus (HIV) infection among psychiatric patients in a New York City shelter for homeless men. We reviewed the records of all 90 men discharged from the shelter psychiatry program to community housing over a 2-year period. HIV serostatus was recorded for 62 of the 9
Increasing frequency of heterosexually transmitted AIDS in southern Florida: artifact or reality?: Am J Public Health. 1993 Apr;83(4):571-3. Unique Identifier : AIDSLINE MED/93212874; Nwanyanwu OC; Conti LA; Ciesielski CA; Stehr-Green JK; Berkelman RL; Lieb S; Witte JJ; National Center for Infectious Diseases, Centers for Disease; Control and Prevention, Atlanta, Ga. 30333.; Acquired immunodeficiency syndrome (AIDS) cases reported as the result of heterosexual contact have been increasing in the United States , with Florida reporting a disproportionate number. We investigated 168 such AIDS cases from southern Florida. After follow-up, 50 (30%) patients were
Public reactions to AIDS in the United States: a second decade of stigma.: Am J Public Health. 1993 Apr;83(4):574-7. Unique Identifier : AIDSLINE MED/93212875; Herek GM; Capitanio JP; Department of Psychology, University of California, Davis; 95616-8686.; The pervasiveness of stigma in the United States related to the acquired immunodeficiency syndrome (AIDS) was assessed in telephone interviews with a general adult sample (n = 538) and an African-American sample (n = 607). Most respondents manifested at least some stigma. African Ameri
Changes in HIV rates and sexual behavior among homosexual men, 1984 to 1988/92.: Am J Public Health. 1993 Apr;83(4):578-80. Unique Identifier : AIDSLINE MED/93212876; Silvestre AJ; Kingsley LA; Wehman P; Dappen R; Ho M; Rinaldo CR; Department of Infectious Diseases and Microbiology, Graduate; School of Public Health, University of Pittsburgh, Pa.; Data were collected from 1614 homosexual and bisexual men in 1984 through 1985 and from 1988 to 1992 in Pittsburgh. Of the men entering the study since 1988, 16% reported engaging in unprotected anal receptive intercourse with more than one partner during the 6 months before their visit. Approximately 7% of the younge
HIV surveillance testing: taking advantage of the disadvantaged [letter] [see comments]: Am J Public Health. 1993 Apr;83(4):597-8. Unique Identifier : AIDSLINE MED/93212884; Isaacman SH
Colorado's HIV partner notification program [letter; comment]: Am J Public Health. 1993 Apr;83(4):598. Unique Identifier : AIDSLINE MED/93212885; Vernon TM; Mangione EJ; Hoffman RE; Spencer NE; Wolf FC
Non-Hodgkin's lymphoma and occupational exposure to hair dyes among people with AIDS [letter; comment]: Am J Public Health. 1993 Apr;83(4):598-9. Unique Identifier : AIDSLINE MED/93212886; Cote TR; Dosemeci M; Rothman N; Banks RB; Biggar RJ
[Gastroesophageal reflux in pediatric neurologic patients]: An Esp Pediatr. 1993 Mar;38(3):232-6. Unique Identifier : AIDSLINE MED/93212989; Vega Gutierrez ML; Benito Fernandez C; Alvarez Gomez MJ; Hernandez Lizoain JL; Narbona Garcia J; Villa Elizaga L; Departamento de Pediatria, Unidad de Neurologia Infantil,; Clinica Universitaria, Facultad de Medicina, Universidad de; Navarra, Pamplona.; With the aim of evaluating the incidence of gastroesophageal reflux (GER) in neurologic pediatric patients with severe motor and/or psychiatric involvement, a retrospective study of 140 infants followed at the Neuropediatric Unit was realized. Forty-five patients (32.1%) had moderate to severe mental retardation (ms R
Pharmacokinetics and pharmacodynamics of granulocyte-macrophage colony-stimulating factor and zidovudine in patients with AIDS and severe AIDS-related complex.: Antimicrob Agents Chemother. 1993 Mar;37(3):512-22. Unique Identifier : AIDSLINE MED/93213124; Hewitt RG; Morse GD; Lawrence WD; Maliszewski ML; Santora J; Bartos L; Bonnem E; Poiesz B; Division of Infectious Disease, School of Medicine and; Biosciences, State University of New York, Buffalo.; Granulocytopenia is a complication of human immunodeficiency virus disease, as well as a toxic manifestation of zidovudine therapy. To evaluate pharmacokinetic and pharmacodynamic relationships, 11 AIDS-AIDS-related complex patients who had developed zidovudine-associated granulocytopenia (mean absolute neutrophil cou
Safety, tolerance, and pharmacokinetics of systemic ribavirin in children with human immunodeficiency virus infection.: Antimicrob Agents Chemother. 1993 Mar;37(3):532-9. Unique Identifier : AIDSLINE MED/93213126; Connor E; Morrison S; Lane J; Oleske J; Sonke RL; Connor J; Department of Pediatrics, Children's Hospital of New Jersey,; Newark.; Eleven pediatric patients, aged 1 to 10 years and with symptomatic human immunodeficiency virus infection, were treated with 6 or 10 mg of oral ribavirin per kg of body weight daily for 60 days. Safety and pharmacokinetic parameters were monitored; five children had comprehensive pharmacokinetic evaluations. The child
The importance of light in the anti-HIV effect of hypericin.: Antiviral Res. 1993 Feb;20(2):173-8. Unique Identifier : AIDSLINE MED/93213146; Hudson JB; Harris L; Towers GH; Division of Medical Microbiology, University of British Columbia,; Vancouver, Canada.; The requirement for light in the anti-HIV-1 activity of hypericin was investigated. The hypericin concentration-dependence and light dosage-dependence of the reaction were measured. Under conditions in which hypericin caused substantial inactivation of HIV-1, there was a strict requirement for visible light. Only when
Opportunistic cerebral vasculopathy and stroke in patients with the acquired immunodeficiency syndrome.: Arch Neurol. 1993 Apr;50(4):430-2. Unique Identifier : AIDSLINE MED/93213231; Kieburtz KD; Eskin TA; Ketonen L; Tuite MJ; Department of Neurology, University of Rochester Medical Center,; NY.; OBJECTIVE--To describe an unusual cause of stroke in patients with the acquired immunodeficiency syndrome. DESIGN--An observational case series of hospitalized patients with subsequent autopsy. MEASURES--Clinical, radiological, and pathological examinations were performed. RESULTS--In three of 14 patients with stroke,
Structural studies on synthetic peptides from the principal neutralizing domain of HIV-1 gp120 that bind to CD4 and enhance HIV-1 infection.: Biochem Biophys Res Commun. 1993 Mar 15;191(2):364-70. Unique Identifier : AIDSLINE MED/93213265; Dettin M; De Rossi A; Autiero M; Guardiola J; Chieco-Bianchi L; Di Bello C; Institute of Industrial Chemistry, University of Padua, Italy.; In previous studies we have demonstrated that synthetic peptides, corresponding to sequences in the (307-330) region of the gp120 principal neutralizing domain of different HIV-1 isolates are specifically recognized by a site distinct from the high affinity gp120-binding site of CD4. Interestingly, a peptide designed
Constitutive expression and production of tumor necrosis factor-beta in T-cell lines infected with HTLV-I and HTLV-II.: Biochem Biophys Res Commun. 1993 Mar 15;191(2):371-7. Unique Identifier : AIDSLINE MED/93213266; Nakajima T; Kitamura K; Yamashita N; Sakane T; Mizushima Y; Delespesse G; Lal RB; University of Montreal, Research Center Notre-Dame Hospital,; Quebec, Canada.; A highly sensitive enzyme-linked immunoassay was developed to detect soluble levels of TNF-beta. Analysis of TNF-beta in culture supernatants from long-term T-cell lines infected with human T-cell lymphotropic virus (HTLV) types I and II demonstrated elevated levels of TNF-beta when compared with uninfected T-cell lin
Determining the prevalence of human immunodeficiency virus (HIV) within a residential facility for persons with mental retardation.: Am J Ment Retard. 1993 Mar;97(5):585-8. Unique Identifier : AIDSLINE MED/93213492; Pledgie TK; Schumacher SH; Division of Mental Retardation, Delaware Health and Social; Services, Dover 19903.; Administrators of residential facilities for persons with mental retardation must take a proactive stance in determining the prevalence of HIV in the population. Administrators of the Stockley Center, a 345-bed ICF/MR, approached the issue utilizing a double-blinded seroprevalence study. Their aim was to use results f
[AIDS virus]: No To Hattatsu. 1993 Mar;25(2):156-62. Unique Identifier : AIDSLINE MED/93213541; Ushijima H; Shibuya A; AIDS Research Center, National Institute of Health, Tokyo.; A Japanese child case of subacute progressive encephalopathy was presented. Not only the pathological findings of HIV growth in microglias, astrocytes and macrophages in the central nervous system, but also the pathobiological findings of neuronal apoptosis were shown as etiologies of HIV encephalopathy. Epidemiology,
Priorities and practice in tropical paediatrics.: J Paediatr Child Health. 1993 Feb;29(1):12-5. Unique Identifier : AIDSLINE MED/93213573; Biddulph J; Department of Child Health, Royal Children's Hospital, Brisbane,; Queensland, Australia.; More than 14 million children under 5 years of age die annually in the Third World, mainly due to diarrhoea, pneumonia, malaria and immunizable diseases. The problems of poverty, malnutrition, poor sanitation, illiteracy and high fertility that traditionally are associated with underdevelopment are now being compounde
Characterization and biological activity of 8-substituted analogues of 2',5'-oligoadenylates [published erratum appears in Biochim Biophys Acta 1993 Jul 11;1157(3):337]: Biochim Biophys Acta. 1993 Mar 21;1156(3):321-6. Unique Identifier : AIDSLINE MED/93213839; Nagai K; Kanbara K; Nakashima H; Yamamoto N; Suhadolnik RJ; Takaku H; Department of Industrial Chemistry, Chiba Institute of; Technology, Japan.; Analogues of the 2 ,5 -linked adenylate trimer 5 -monophosphates (p5 A2 p5 A2 p5 A) containing 8-hydroxyadenosine and 8-mercaptoadenosine in the first, second, and third nucleotide positions were tested for their ability to bind to and activate RNase L of mouse L cells. The ability of p5 ASH2 p5 ASH2 p5 ASH (pASH3) (1
Special issue: The family and HIV disease.: AIDS Care. 1993;5(1):1-122. Unique Identifier : AIDSLINE MED/93213875
The extended family and support for people with AIDS in a rural population in south west Uganda: a safety net with holes?: AIDS Care. 1993;5(1):117-22. Unique Identifier : AIDSLINE MED/93213877; Seeley J; Kajura E; Bachengana C; Okongo M; Wagner U; Mulder D; Medical Research Council (UK) Research Programme on AIDS in; Uganda, Uganda Virus Research Institute, Entebbe.; It is commonly assumed that the extended family in Africa provides a safety net for individuals in times of need. This paper examines this assumption using data on the care of people with AIDS in a rural population in South West Uganda . Over a six month period data were collected b
World Health Organization Global AIDS Statistics.: AIDS Care. 1993;5(1):125-8. Unique Identifier : AIDSLINE MED/93213878
Significant relationships and social supports of injecting drug users and their implications for HIV/AIDS services.: AIDS Care. 1993;5(1):23-33. Unique Identifier : AIDSLINE MED/93213879; Stowe A; Ross MW; Wodak A; Thomas GV; Larson SA; National Centre in HIV Social Research, St Vincents Hospital,; Sydney, Australia.; Strong social support networks have been associated with positive outcomes for health and well-being throughout the life-cycle. This paper investigates the structural and functional nature of social support networks of 100 injecting drug users (IDUs) in Sydney and the implications for HIV/AIDS services. Using a modifi
The family and HIV disease [editorial]: AIDS Care. 1993;5(1):3-4. Unique Identifier : AIDSLINE MED/93213880; Bor R; Elford J; Hart G; Sherr L
The child in the family--responding to AIDS and HIV.: AIDS Care. 1993;5(1):35-42. Unique Identifier : AIDSLINE MED/93213881; Melvin D; Sherr L; St Mary's Hospital, London, UK.; This study examines the psychosocial needs of children with AIDS and HIV infection based on a cohort of 18 infected children. Fifteen of the children live with their mothers, nine of whom are single mothers. For 14 children the mother is HIV +ve and for a further 8 the father is also HIV +ve. Many children have siblin
Psychological distress and the role of significant others in a population of gay/bisexual men in the era of HIV.: AIDS Care. 1993;5(1):43-54. Unique Identifier : AIDSLINE MED/93213882; Britton PJ; Zarski JJ; Hobfoll SE; Kent State University, OH 44242.; This study, based on The Conservation of Resources Theory (COR), explores the relationship between social resources and psychological distress, as reported by gay/bisexual men who are at varying degrees of risk for HIV. This study involves theory-based stress research, and adds to the body of literature that addresses
The impact of HIV/AIDS on the family and other significant relationships: the African clan revisited.: AIDS Care. 1993;5(1):5-22. Unique Identifier : AIDSLINE MED/93213883; Ankrah EM; Faculty of Social Sciences, Makerere University, Kampala, Uganda.; Although changing in size, structure and function, the African family has persistently maintained its place as the central human social unit. Beyond the traditional African family--whether in the nuclear or the extended form--is a network of people, most of whom are connected by kin or blood relationships, termed the
AIDS and the urban family: its impact in Kampala, Uganda.: AIDS Care. 1993;5(1):55-70. Unique Identifier : AIDSLINE MED/93213884; McGrath JW; Ankrah EM; Schumann DA; Nkumbi S; Lubega M; Department of Anthropology, Case Western Reserve University,; Cleveland, OH 44106.; Twenty-two families with one or more adult members with AIDS were extensively interviewed about sociodemographic variables, knowledge of AIDS, responses to AIDS, material needs, psychological state and perception of stigma. A total of 24 individuals were enrolled. Seven subjects did not permit contact with family memb
AIDS and the family: implications for counselling.: AIDS Care. 1993;5(1):71-8. Unique Identifier : AIDSLINE MED/93213885; Lippmann SB; James WA; Frierson RL; Department of Psychiatry and Behavioural Sciences, School of; Medicine, University of Louisville, KY 40202.; The presence of HIV spectrum illness stimulates a powerful emotional reaction from a patient s family and friends. Grief and shock over the infection, and its implications are frequent observations. Sadness, anxiety, helplessness and anger are also common. Health care staff should address these responses in order to s
A family with HIV and haemophilia.: AIDS Care. 1993;5(1):79-85. Unique Identifier : AIDSLINE MED/93213886; Goldman E; Miller R; Lee CA; Haemophilia Centre, Royal Free Hospital, London, UK.; An Indian Sikh family affected with both HIV and haemophilia is described. The use of interpreters; the regular follow-up in the Concorde trial; family therapy and help with practical problems have been approaches used to help the family despite language and cultural differences.
Social support and HIV [editorial]: AIDS Care. 1993;5(1):87-104. Unique Identifier : AIDSLINE MED/93213887; Green G; This paper reviews research about the relationship between social support and health for people with HIV. Current studies linking social support and HIV are described and the major findings summarized in order to identify gaps in the literature. It is argued that, to date, research in this area has focused primarily u
[Utilization of an emergency service by patients with HIV infection]: Enferm Infecc Microbiol Clin. 1993 Jan;11(1):14-8. Unique Identifier : AIDSLINE MED/93213889; Gutierrez A; Suarez MD; Ortiz de Luna I; Varona M; Ugalde F; Cisterna R; Marinez M; Servicio de Urgencias, Hospital Civil de Bilbao.; BACKGROUND AND METHODS: To know the impact of HIV infection in a hospital emergency department the health care episodes of seropositive individuals are reviewed in a retrospective study from the January 1 to March 31, 1992. Cases have been identified comparing the list of those infected by HIV with the users of the de
[Oro-esophageal candidiasis resistant to fluconazole in patients with AIDS (see comments)]: Enferm Infecc Microbiol Clin. 1993 Jan;11(1):36-9. Unique Identifier : AIDSLINE MED/93213893; Diz P; Ocampo A; Miralles C; Otero I; Iglesias I; Martinez C; Facultad de Medicina y Odontologia, Universidad de Santiago de; Compostela, La Coruna.; BACKGROUND: Fluconazole-resistant Candida albicans has been seldom reported in the literature. in this study, two clinical cases of oro-esophageal candidosis resistant to this antifungal drug are described. METHOD: Infection was confirmed by isolation of yeasts (culture of mouth swabs, oesophagoscopy and histology of
[Acute toxoplasmosis. Laboratory diagnosis]: Enferm Infecc Microbiol Clin. 1993 Jan;11(1):4-7. Unique Identifier : AIDSLINE MED/93213894; Nogues A; Garcia M; Ribelles E; Rivas C; Servicio de Analisis Clinicos-Microbiologia, Hospital Arnau de; Vilanova, Lerida.; BACKGROUND: The microbiological diagnosis of acute toxoplasmosis in immunosuppressed patients, cannot, usually, be done through serological techniques. The methods for isolation or direct detection of parasite are the only ones that might be helpful to determine an earlier diagnosis, on these patients. METHODS AND RES
[Bacteremia caused by Campylobacter jejuni resistant to nalidixic acid and fluoroquinolones (letter)]: Enferm Infecc Microbiol Clin. 1993 Jan;11(1):58-9. Unique Identifier : AIDSLINE MED/93213904; Gomez JL; Alos JI; Amor E; Cogollos R; Perez A
Protein S deficiency in men with long-term human immunodeficiency virus infection [see comments]: Blood. 1993 Apr 1;81(7):1801-7. Unique Identifier : AIDSLINE MED/93214033; Stahl CP; Wideman CS; Spira TJ; Haff EC; Hixon GJ; Evatt BL; Division of HIV/AIDS, National Center for Infectious Diseases,; Centers for Disease Control and Prevention, Atlanta, GA 30333.; Decreases in protein S levels have recently been reported in some human immunodeficiency virus (HIV)-infected patients. To examine predisposing factors, 25 men randomly selected from a long-term study of HIV-infected patients were studied. The minimum mean duration of HIV seropositivity in this group was 106.6 months
Complement and virus-specific antibody-dependent infection of normal B lymphocytes by human immunodeficiency virus type 1.: Blood. 1993 Apr 1;81(7):1808-18. Unique Identifier : AIDSLINE MED/93214034; Gras G; Richard Y; Roques P; Olivier R; Dormont D; Laboratoire de Neuropathologie Experimentale et Neurovirologie,; Commissariat a l'Energie Atomique, Fontenay aux Roses, France.; We tested the susceptibility of human purified, normal B lymphocytes to human immunodeficiency virus type 1 (HIV-1) infection, in the presence or absence of complement-sufficient serum and of virus-specific antibodies. Virus replication was detected when cells were infected in the presence of both complement and anti-
Acquired immunodeficiency syndrome-associated non-Hodgkin's lymphomas and other malignancies in patients with hemophilia.: Blood. 1993 Apr 1;81(7):1889-97. Unique Identifier : AIDSLINE MED/93214045; Ragni MV; Belle SH; Jaffe RA; Duerstein SL; Bass DC; McMillan CW; Lovrien EW; Aledort LM; Kisker CT; Stabler SP; et al; University of Pittsburgh School of Medicine, Hemophilia Center of; Western Pennsylvania 15219.; Non-Hodgkin s lymphoma (NHL) is the most common human immunodeficiency virus (HIV)-associated malignancy in hemophiliacs. We studied the incidence and clinicopathologic features of NHL in 3,041 hemophiliacs followed at 18 US Hemophilia Centers between 1978 and 1989. Of the 1,295 (56.6%) who were HIV(+), 253 (19.5%) de
[Results of studies from the AIDS counseling center of the Frankfurt/M. city health office January 1990 to December 1991]: Gesundheitswesen. 1993 Feb;55(2):68-73. Unique Identifier : AIDSLINE MED/93214236; Steiger MT; Peters M; Fienbork B; Stille W; Doerr HW; Stadtgesundheitsamt Frankfurt/M.; Between January 1990 and December 1991 5854 clients entered the AIDS-Counselling Service of the Municipal Health Department in Frankfurt/M; 1997 (34%) of them were female and 3857 (66%) male. In 5228 cases blood samples were examined for HIV-antibodies and the prevalence of positive tests was 84 (1.6%). Among the subj
[Report of the status of HIV and AIDS in Germany (news)]: Gesundheitswesen. 1993 Feb;55(2):86-7. Unique Identifier : AIDSLINE MED/93214241
[Proposal of the Society of German AIDS Foundations for singular support from the organization (news)]: Gesundheitswesen. 1993 Feb;55(2):87. Unique Identifier : AIDSLINE MED/93214242
Effect of using safer blood products on prevalence of HIV infection in haemophilic Canadians. Canadian Hemophilia Clinic Directors Group.: BMJ. 1993 Jan 30;306(6873):306-7. Unique Identifier : AIDSLINE MED/93214349
Avoiding exposure to HIV and hepatitis [letter; comment]: BMJ. 1993 Jan 30;306(6873):335. Unique Identifier : AIDSLINE MED/93214374; Macintyre IM; Currie JS
Avoiding exposure to HIV and hepatitis [letter; comment]: BMJ. 1993 Jan 30;306(6873):335-6. Unique Identifier : AIDSLINE MED/93214375; Hurren JS
Avoiding exposure to HIV and hepatitis [letter; comment]: BMJ. 1993 Jan 30;306(6873):336. Unique Identifier : AIDSLINE MED/93214376; Nicholson F; Tilzey AJ; Banatvala JE
Clinical symptoms associated with seroconversion for HIV-1 among misusers of intravenous drugs: comparison with homosexual seroconverters and infected and non-infected intravenous drug misusers.: BMJ. 1993 Feb 6;306(6874):371-3. Unique Identifier : AIDSLINE MED/93214391; Mientjes GH; van Ameijden EJ; Weigel HM; van den Hoek JA; Coutinho RA; Municipal Health Service, Department of Public Health and; Environment, Amsterdam, The Netherlands.; OBJECTIVE--To study the clinical symptoms associated with seroconversion for HIV-1 among misusers of intravenous drugs. DESIGN--Case-control study in cohorts of drug misusers and homosexual men. SETTING--Outpatient clinic, Municipal Health Service, Amsterdam. SUBJECTS--Misusers of intravenous drugs from our prospectiv
HIV transmission, travel, and Thailand [letter; comment]: BMJ. 1993 Feb 6;306(6874):394. Unique Identifier : AIDSLINE MED/93214410; Gruer L; Cowan L; Elliott L; Farrow K; Sloan D
Sexually transmitted diseases and HIV-1 infection among homosexual men in England and Wales [see comments]: BMJ. 1993 Feb 13;306(6875):426-8. Unique Identifier : AIDSLINE MED/93214437; Evans BG; Catchpole MA; Heptonstall J; Mortimer JY; McCarrigle CA; Nicoll AG; Waight P; Gill ON; Swan AV; Public Health Laboratory Service AIDS Centre, Communicable; Disease Surveillance Centre, London.; OBJECTIVE--To examine surveillance data for evidence of changing sexual behaviour and continuing transmission of HIV-1 among men who have sex with men. DESIGN--Analytic study of surveillance data on sexually transmitted diseases. SETTING--England and Wales. MAIN OUTCOME MEASURES--Number of cases of rectal gonorrhoea a
New clinics for HIV testing: a waste of money [letter] [see comments]: BMJ. 1993 Feb 13;306(6875):462. Unique Identifier : AIDSLINE MED/93214479; Evans BA
Children of parents infected with HIV in Lothian [letter]: BMJ. 1993 Mar 6;306(6878):649-50. Unique Identifier : AIDSLINE MED/93214556; Ronald PJ; Robertson JR; Duncan BM; Thomson AS
Risks to surgeons and patients from HIV and hepatitis [letter; comment]: BMJ. 1993 Mar 6;306(6878):652-3. Unique Identifier : AIDSLINE MED/93214566; Boxall EH
Differential therapeutic response in AIDS-associated polyarthritis [letter]: Br J Rheumatol. 1993 Apr;32(4):346-7. Unique Identifier : AIDSLINE MED/93214742; Kindelan JM; Ortega C; Gonzalez J; Jurado R; Collantes E; Martinez FG; Santamaria M
Extensive condylomata acuminata of male urethra: management by ventral urethrotomy [see comments]: Br J Urol. 1993 Feb;71(2):204-7. Unique Identifier : AIDSLINE MED/93214767; Kesner KM; Department of Urology, Cecilia Makiwane Hospital, Mdantsane,; Ciskei, South Africa.; Between 1982 and 1990, 4 males with extensive intraurethral warts presented with marked inflammation of the external genitalia. When sepsis had settled all patients underwent ventral urethrotomy, in which the urethra was divided median as far back as was necessary to expose all of the warts. Surgical and electro-excis
HIV envelope protein-induced neuronal damage and retardation of behavioral development in rat neonates.: Brain Res. 1993 Feb 19;603(2):222-33. Unique Identifier : AIDSLINE MED/93214800; Hill JM; Mervis RF; Avidor R; Moody TW; Brenneman DE; Unit on Neurochemistry, National Institute of Child Health and; Human Development, National Institutes of Health, Bethesda, MD; 20892.; Cognitive and motor impairment are common symptoms among patients infected with the human immunodeficiency virus (HIV), including children who suffer neurological deficits and are frequently developmentally impaired. The HIV envelope protein, gp120, which has been shown to be toxic to neurons in culture, is shed in ab
Physicians and abortion [letter; comment]: Can Med Assoc J. 1993 Apr 15;148(8):1276-7. Unique Identifier : AIDSLINE MED/93214927; Sutherland LE
Ottawa announces hike in funding for AIDS research, education [news]: Can Med Assoc J. 1993 Apr 15;148(8):1347. Unique Identifier : AIDSLINE MED/93214939
In the US, AIDS has become a marginal disease that affects thousands.: Can Med Assoc J. 1993 Apr 15;148(8):1369, 1372. Unique Identifier : AIDSLINE MED/93214942; Gray C
Seek funding from provinces or private sector, not Ottawa, researchers told [published erratum appears in Can Med Assoc J 1993 Jul 1;149(1):18-9]: Can Med Assoc J. 1993 Apr 15;148(8):1380-1, 1384. Unique Identifier : AIDSLINE MED/93214945; Spurgeon D
Commentary: ethics, ethics everywhere--ascertainment bias in new disorders [comment]: Curr Probl Pediatr. 1993 Feb;23(2):42-3. Unique Identifier : AIDSLINE MED/93215304; Fost N
Invasive infection with Mycobacterium genavense in three children with the acquired immunodeficiency syndrome.: Eur J Clin Microbiol Infect Dis. 1993 Jan;12(1):37-43. Unique Identifier : AIDSLINE MED/93215672; Nadal D; Caduff R; Kraft R; Salfinger M; Bodmer T; Kirschner P; Bottger EC; Schaad UB; Department of Pediatrics, University of Zurich, Switzerland.; Three children with human immunodeficiency virus infection and invasive infection with Mycobacterium genavense are reported. Fever spikes, abdominal cramps and distension, diarrhea or ileus, and anemia were the predominant symptoms in the severely immunodeficient patients (CD4 lymphocytes
Association of hepatitis B and human immunodeficiency virus infections in Tanzanian population groups.: Eur J Clin Microbiol Infect Dis. 1993 Jan;12(1):62-4. Unique Identifier : AIDSLINE MED/93215679; Shao JF; Haukenes G; Yangi E; Vollset SE; Department of Microbiology and Immunology, Muhimbili College of; Health Sciences, Dar es Salaam, Tanzania.; A study was performed to determine whether there is a correlation between hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection in population groups in the Dar es Salaam area in Tanzania where HBV infection is endemic. A panel of 460 sera from army recruits, he
[Therapy of aspergillus infection in AIDS (news)]: Fortschr Med. 1993 Mar 10;111(7):14. Unique Identifier : AIDSLINE MED/93216196
Using interactive video to supplement HIV counseling.: Hosp Community Psychiatry. 1993 Apr;44(4):383-5. Unique Identifier : AIDSLINE MED/93216248; Card CA; Jacobsberg LB; Moffatt M; Fishman B; Perry S; Department of Psychiatry, Cornell University Medical College-New; York Hospital, New York 10021.
What do you say to a child with AIDS?: Hastings Cent Rep. 1993 Mar-Apr;23(2):6-12. Unique Identifier : AIDSLINE MED/93216438; Lipson M; Harlem Hospital, New York, NY.
[Morphology and follow-up of seborrheic eczema] ]: Hautarzt. 1993 Mar;44(3):181. Unique Identifier : AIDSLINE MED/93216451; Elsner P; Dermatologische Klinik, Universitatsspital Zurich.
Persistently human immunodeficiency virus type 1-infected T cell clone expressing only doubly spliced mRNA exhibits reduced cell surface CD4 expression.: Jpn J Cancer Res. 1993 Feb;84(2):153-62. Unique Identifier : AIDSLINE MED/93216509; Kishi M; Nishino Y; Ohki K; Kimura T; Ikuta K; Section of Serology, Hokkaido University, Sapporo.; Several cell clones possessing the human immunodeficiency virus type 1 (HIV-1) genome, consisting of an almost full-length DNA sequence, were isolated by limiting dilution of the clonal cell line M10 derived from MT-4 that survived infection with HIV-1 vpr mutant (M10/vpr-). One of the isolated clones (termed Vpr-1) e
Pyridoxal 5'-phosphate binds specifically to soluble CD4 protein, the HIV-1 receptor. Implications for AIDS therapy.: J Biol Chem. 1993 Apr 15;268(11):7643-5. Unique Identifier : AIDSLINE MED/93216724; Salhany JM; Schopfer LM; Veterans Administration Medical Center, Omaha, Nebraska.; Considerable effort is being made to design anti-viral drugs for the human immunodeficiency virus type 1 (HIV-1) infection process. Some of this work has focused on CD4 protein, the HIV-1 receptor on T helper lymphocytes. One drug that binds to CD4 protein and inhibits both viral infection and growth is DIDS (4,4 -dii
Skin lesion in an acutely ill man with HIV.: Hosp Pract (Off Ed). 1993 Apr 15;28(4):100. Unique Identifier : AIDSLINE MED/93216865; Mantzoros C; Bazzi M; Hadidi MF; Wayne State University, Detroit.
Human T lymphotropic virus type I associated myelopathy with pulmonary and cutaneous lesions.: J Clin Pathol. 1993 Mar;46(3):273-5. Unique Identifier : AIDSLINE MED/93216960; Kuwabara H; Katanaka J; Nagai M; Uda H; Hojo W; Yamada A; Miki H; Takeuchi H; Teranishi K; Matsuda K; et al; Department of Pathology, Kagawa Medical School, Japan.; A necropsy case of human T lymphotropic virus I (HTLV-I) associated myelopathy (HAM) in a 64 year old man with serological and genetical confirmation of HTLV-I infection is reported. The spinal cord, lung, and skin were mainly affected. Severe degeneration had occurred in the spinal cord, not only in the lateral colum
Rectal Hodgkin's disease in acquired immune deficiency syndrome [letter]: J Clin Gastroenterol. 1993 Mar;16(2):171-3. Unique Identifier : AIDSLINE MED/93217200; Pinover W; Pickens P; Cohn J; Tester W; Nieman RE; Redmond J 3d; Auerbach HE
Examining HIV-related knowledge among adults in the U.S.: J Health Soc Behav. 1993 Mar;34(1):23-36. Unique Identifier : AIDSLINE MED/93217211; LeBlanc AJ; Department of Sociology, University of California, Los Angeles; 90024-1551.; Supplemental AIDS data from the 1987 National Health Interview Survey indicate that adults in the U.S. know the most frequent modes of HIV transmission, but lack a more comprehensive understanding of HIV and AIDS. Elements from a diffusion model were isolated to create a path-analytic framework for examining the effec
Determinants of social support among gay men: the context of AIDS.: J Health Soc Behav. 1993 Mar;34(1):37-53. Unique Identifier : AIDSLINE MED/93217212; Turner HA; Hays RB; Coates TJ; Department of Sociology, University of New Hampshire, Horton; Social Science Center, Durham, NH 03824-3586.; In this study, the determinants of social support are examined among a probability sample of gay men residing in San Francisco. Using two waves of data (collected in 1985 and 1987), cross-sectional and longitudinal analyses focused on the effects of five sets of factors (demographic, community integration/network, AID
Monitoring AIDS and other rare population events: a network approach.: J Health Soc Behav. 1993 Mar;34(1):7-22. Unique Identifier : AIDSLINE MED/93217214; Laumann EO; Gagnon JH; Michaels S; Michael RT; Schumm LP; Department of Sociology, University of Chicago, IL 60637.; This paper replicates and extends an earlier attempt to use data from the General Social Survey (GSS) to track the distribution of AIDS across demographic subgroups. (The GSS asks respondents whether they know a person with AIDS [PWA].) The gender, racial, age, and regional composition of the set of PWAs reported by G
HIV seroprevalence in the Bell Flower STD Clinic.: Indiana Med. 1993 Mar-Apr;86(2):142-7. Unique Identifier : AIDSLINE MED/93217221; Minshall ME; Fleissner ML; Indiana State Department of Health, Epidemiology Resource Center.
Brain biopsy in Indiana AIDS patients.: Indiana Med. 1993 Mar-Apr;86(2):158-61. Unique Identifier : AIDSLINE MED/93217223; Michael F; Shapiro S; Goodman J; Hall D; Indiana University School of Medicine, Department of Surgery,; Indianapolis.; The neuropathologic findings of brain biopsies in a series of Indiana AIDS patients were reviewed. All subjects displayed focal lesions on radiographic studies. The three most common diagnoses were toxoplasmosis, progressive multifocal leukoencephalopathy and primary central nervous symptoms (CNS) lymphoma. These find
Principles and techniques of tissue banking.: Instr Course Lect. 1993;42:359-62. Unique Identifier : AIDSLINE MED/93217282; Czitrom AA
Renal failure due to sulphadiazine in AIDS patients with cerebral toxoplasmosis.: J Intern Med. 1993 Apr;233(4):365-7. Unique Identifier : AIDSLINE MED/93217431; Farinas MC; Echevarria S; Sampedro I; Gonzalez A; Perez del Molino A; Gonzalez-Macias J; Department of Internal Medicine, Hospital Universitario Marques; de Valdecilla, Santander, Cantabria, Spain.; Cerebral toxoplasmosis is optimally treated with the combination of high doses of sulphadiazine and pyrimethamine. We described two patients with AIDS treated for cerebral toxoplasmosis who developed renal failure due to sulphadiazine-induced crystalluria. Symptoms and renal failure were rapidly reversed with urine al
Quantitative leukoviremia and immune complex-dissociated antigenemia as predictors of infection status in children born to mothers infected with human immunodeficiency virus type 1.: J Pediatr. 1993 Apr;122(4):524-31. Unique Identifier : AIDSLINE MED/93217753; Ikeda MK; Andiman WA; Mezger JL; Shapiro ED; Miller G; Department of Pediatrics, Yale University School of Medicine, New; Haven, CT 06510.; Four methods of culturing human immunodeficiency virus type 1 (HIV-1) from peripheral blood mononuclear cells and two serum antigen tests were assessed as predictors of infection status in children born to HIV-1-infected mothers. Of 36 infants whose cocultures were quantitative, all 15 who were deemed to be infected w
Experimental gingivitis during pregnancy and post-partum: immunohistochemical aspects.: J Periodontol. 1993 Mar;64(3):211-8. Unique Identifier : AIDSLINE MED/93217807; Raber-Durlacher JE; Leene W; Palmer-Bouva CC; Raber J; Abraham-Inpijn L; Department of General Pathology and Internal Medicine, Academic; Center for Dentistry Amsterdam, (ACTA), The Netherlands.; The histoimmunological response of 8 individuals was studied longitudinally in relation to the development of experimental gingivitis during pregnancy and post-partum. At day 0 as well as at day 14 of experimental gingivitis the mean periodontal pocket bleeding index (PPBI) was higher during pregnancy than post-partum
[Tumor necrosis factor and AIDS]: Yakugaku Zasshi. 1993 Jan;113(1):1-18. Unique Identifier : AIDSLINE MED/93217816; Kobayashi N; Department of Virology and Parasitology, School of Medicine,; Yamaguchi University, Kogushi Ube, Japan.; Human immunodeficiency virus (HIV), an etiologic agent of AIDS, belongs to lentivirus subfamily of retroviruses. In striking contrast to oncoviruses HIV does not transform cells but instead causes chronic progressive diseases. This feature is demonstrable in vitro by dramatic cytopathic effects upon virus/cell cocultu
Cyclic sulfolanes as novel and high affinity P2 ligands for HIV-1 protease inhibitors.: J Med Chem. 1993 Apr 2;36(7):924-7. Unique Identifier : AIDSLINE MED/93217965; Ghosh AK; Thompson WJ; Lee HY; McKee SP; Munson PM; Duong TT; Darke PL; Zugay JA; Emini EA; Schleif WA; et al; Department of Medicinal Chemistry, Molecular Biology, and Virus; and Cell Biology, Merck Research Laboratories, West Point,; Pennsylvania 19486.
Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductase.: J Mol Biol. 1993 Mar 20;230(2):679-80. Unique Identifier : AIDSLINE MED/93218006; Stammers DK; Delves C; Ballantine S; Jones EY; Stuart DI; Achari A; Bryant PK; Champness JN; Wellcome Research Laboratories, Beckenham, Kent, U.K.; Dihydrofolate reductase from Pneumocystis carinii has been crystallized in a form suitable for high resolution X-ray diffraction studies. Recombinant enzyme that had been refolded following solubilization in guanidinium hydrochloride was crystallized as both a ternary complex with the cofactor NADPH and the inhibitor
Social catastrophe: orphaned by AIDS [letter; comment]: JAMA. 1993 Apr 21;269(15):1942. Unique Identifier : AIDSLINE MED/93218051; Clever LH
Social catastrophe: orphaned by AIDS [letter; comment]: JAMA. 1993 Apr 21;269(15):1942. Unique Identifier : AIDSLINE MED/93218052; Robinson RP; Monk E; Coon L; Blanford C; Mason S
[Intraocular inflammation--retrospect of the year 1991]: Klin Monatsbl Augenheilkd. 1993 Jan;202(1):64-70. Unique Identifier : AIDSLINE MED/93218220; Bialasiewicz AA; Rohrschneider T; Universitats-Augenklinik Munster.
Cytotoxic activities of recombinant immunotoxins composed of Pseudomonas toxin or diphtheria toxin toward lymphocytes from patients with adult T-cell leukemia.: Leukemia. 1993 Apr;7(4):553-62. Unique Identifier : AIDSLINE MED/93218273; Kreitman RJ; Chaudhary VK; Waldmann TA; Hanchard B; Cranston B; FitzGerald DJ; Pastan I; Laboratory of Molecular Biology, National Cancer Institute,; National Institutes of Health, Bethesda, MD 20892.; We have previously shown that the recombinant single-chain immunotoxin anti-Tac(Fv)-PE40, composed of the variable domains of the anti-Tac monoclonal antibody in a single-chain form joined to a derivative of Pseudomonas exotoxin (PE), is cytotoxic toward malignant cells from adult T-cell leukemia (ATL) patients. Using
[The inappropriate antidiuretic hormone secretion syndrome associated with cryptococcal meningitis in a patient with the acquired immunodeficiency syndrome]: Med Clin (Barc). 1993 Mar 20;100(11):420-2. Unique Identifier : AIDSLINE MED/93218303; Brea Hernando AI; Bandres Franco E; Aguirre Minana T; Ezquerra Lezcano M; Borque de Larrea L; Servicio de Medicina Interna, Hospital San Millan, Logrono, La; Rioja.; Meningitis and other infectious diseases of the central nervous system are predisposing causes of the inadequate secretion syndrome of the antidiuretic hormone (ISADH). The association between the acquired immunodeficiency syndrome (AIDS) and ISADH is recognized but little studied. In AIDS patients hyponatremia is a f
[Kaposi's sarcoma with pulmonary involvement in a heterosexual man seronegative for the human immunodeficiency virus (letter)]: Med Clin (Barc). 1993 Mar 20;100(11):437. Unique Identifier : AIDSLINE MED/93218308; Belda A; Alberola V; Prats A; Pastor J
[The sicca syndrome and human immunodeficiency virus infection (letter; comment)]: Med Clin (Barc). 1993 Mar 20;100(11):439. Unique Identifier : AIDSLINE MED/93218313; Munoz Fernandez S
Pathogenesis of human immunodeficiency virus infection.: Microbiol Rev. 1993 Mar;57(1):183-289. Unique Identifier : AIDSLINE MED/93218576; Levy JA; Department of Medicine, University of California School of; Medicine, San Francisco 94143-0128.; The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large number of different cells in the body and escaping the host immune response against it. HIV is transmitted primarily through blood and genital fluids and to newborn infants from infected mothers. The steps occurring in infection
Evaluation of structure-antigenicity relationship of peptides from human immunodeficiency virus type 1 (HIV-1) p18 protein by circular dichroism.: Mol Immunol. 1993 Apr;30(5):503-12. Unique Identifier : AIDSLINE MED/93218664; Mabrouk K; Moulard M; Gluckman JC; Romi R; Rochat H; Van Rietschoten J; Bahraoui E; Laboratoire de Biochimie CNRS URA 1455, Faculte de Medecine; Nord, Marseille, France.; The antigenicity of Human Immunodeficiency Virus type 1 (HIV-1) matrix p18 protein was evaluated by analyzing the specificity of anti-p18 antibodies elicited either in HIV-1 infected humans, or in HIV-1 infected or immunized chimpanzees, against a panel of long and short overlapping synthetic peptides [from 12 to 46 a
False positive tests for HIV in a woman with lupus and renal failure [letter] [see comments]: N Engl J Med. 1993 Apr 29;328(17):1281-2. Unique Identifier : AIDSLINE MED/93218691; Jindal R; Solomon M; Burrows L
Pneumococcal appendicitis in a man with HIV infection [letter]: N Engl J Med. 1993 Apr 29;328(17):1282. Unique Identifier : AIDSLINE MED/93218692; Clark JA; Keroack MA
NIH plans to begin AIDS drug trials at earlier stage [news]: Nature. 1993 Apr 1;362(6419):382. Unique Identifier : AIDSLINE MED/93218699; Macilwain C
AIDS. I want a new drug [news]: Nature. 1993 Apr 1;362(6419):396. Unique Identifier : AIDSLINE MED/93218704
Genentech. Clone your own legend [news]: Nature. 1993 Apr 1;362(6419):397. Unique Identifier : AIDSLINE MED/93218706
AIDS administrators plan crisis meeting over future of AZT [news]: Nature. 1993 Apr 8;362(6420):483. Unique Identifier : AIDSLINE MED/93218729; Dickson D; Macilwain C
Albert B. Sabin (1906-1993) [news]: Nature. 1993 Apr 8;362(6420):499. Unique Identifier : AIDSLINE MED/93218735; Koprowski H
Properties of an HIV 'vaccine' [letter; comment]: Nature. 1993 Apr 8;362(6420):504-5; discussion 505-6. Unique Identifier : AIDSLINE MED/93218738; Volvovitz F; Smith G
Properties of an HIV 'vaccine' [letter; comment]: Nature. 1993 Apr 8;362(6420):505; discussion 505-6. Unique Identifier : AIDSLINE MED/93218739; Wahren B; Sandstrom E; Wigzell H
Vaccine compromise [editorial]: Nature. 1993 Apr 15;362(6421):576. Unique Identifier : AIDSLINE MED/93218752
US test of AIDS vaccines is broadened beyond VaxSyn [news]: Nature. 1993 Apr 15;362(6421):581. Unique Identifier : AIDSLINE MED/93218758; Macilwain C
The psychiatric aspects of HIV/AIDS.: N J Med. 1993 Feb;90(2):114-7. Unique Identifier : AIDSLINE MED/93218873; Kennedy CA; UMDNJ-New Jersey Medical School, Newark 07103-2714.; The human immunodeficiency virus (HIV) that causes acquired immunodeficiency syndrome (AIDS) induces a multiplicity of neuropsychiatric symptoms. While some symptoms manifest before acquisition of infection, others become apparent after acquisition of infection.
State HIV-positive physician policy.: N J Med. 1993 Feb;90(2):91. Unique Identifier : AIDSLINE MED/93218880
Human immunodeficiency virus-infected adolescents: the first 50 patients in a New York City program [see comments]: Pediatrics. 1993 Apr;91(4):730-5. Unique Identifier : AIDSLINE MED/93219014; Futterman D; Hein K; Reuben N; Dell R; Shaffer N; Albert Einstein College of Medicine, Montefiore Medical Center,; Bronx, NY 10467.; To address the unique manifestations of human immunodeficiency virus (HIV) among adolescents aged 13 through 21 years, a comprehensive evaluation and treatment program for high-risk and HIV-positive adolescents was developed in New York City in 1987. Among HIV-infected youth, mean age of testing was 18.2 years. One th
Neurologic history and examination results and their relationship to human immunodeficiency virus type 1 serostatus in hemophilic subjects: results from the hemophilia growth and development study [published erratum appears in Pediatrics 1995 Feb;95(2):215]: Pediatrics. 1993 Apr;91(4):736-41. Unique Identifier : AIDSLINE MED/93219015; Bale JF Jr; Contant CF; Garg B; Tilton A; Kaufman DM; Wasiewski W; Dept of Pediatrics, University of Iowa Hospitals and Clinics,; Iowa City 52242.; In a prospective study of the growth and neuropsychologic function of hemophilic subjects, 333 boys, median age of 12.3 years, had baseline neurologic examinations. The study population included 207 individuals (62%) who were seropositive for human immunodeficiency virus type 1 (HIV-1). Overall results indicated that
Secondary structure of the HIV-2 leader RNA comprising the tRNA-primer binding site.: Nucleic Acids Res. 1993 Mar 11;21(5):1171-8. Unique Identifier : AIDSLINE MED/93219077; Berkhout B; Schoneveld I; University of Amsterdam, Department of Virology, Academic Medical; Center, The Netherlands.; The initiation of reverse transcription of a retroviral RNA genome occurs by a tRNA primer bound near the 5 end of the genomic RNA at a position called the primer-binding site (PBS). To understand the molecular basis for this RNA-RNA interaction, the secondary structure of the leader RNA of the human immunodeficiency
In vitro selection of fast-hybridizing and effective antisense RNAs directed against the human immunodeficiency virus type 1.: Nucleic Acids Res. 1993 Mar 25;21(6):1381-7. Unique Identifier : AIDSLINE MED/93219115; Rittner K; Burmester C; Sczakiel G; Forschungsschwerpunkt Angewandte Tumorvirologie, Deutsches; Krebsforschungszentrum, Heidelberg, Germany.; The rate of double strand formation between procaryotic antisense RNA and complementary RNA in vitro is known to correlate with the effectiveness of antisense RNA in vivo. In this work, an in vitro assay for determining the hybridization rates of a large number of antisense RNA species was developed. A set of HIV-1-di
Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein.: Nucleic Acids Res. 1993 Mar 25;21(6):1419-25. Unique Identifier : AIDSLINE MED/93219120; Vink C; Oude Groeneger AM; Plasterk RH; Division of Molecular Biology, The Netherlands Cancer Institute,; Amsterdam.; The integrase (IN) protein of the human immunodeficiency virus (HIV) is required for specific cleavage of the viral DNA termini, and subsequent integration of the viral DNA into target DNA. To identify the various domains of the IN protein we generated a series of IN deletion mutants as fusions to maltose-binding prot
[T4/T8 ratio in bronchoalveolar lavage in sarcoidosis--a marker of activity and/or prognosis?]: Pneumologie. 1993 Feb;47(2):53-9. Unique Identifier : AIDSLINE MED/93219299; de Wall N; Atay Z; Endres P; II. Medizinische Klinik, Nordwest-Krankenhauses Sanderbusch.; In 158 patients with histologically confirmed intrathoracic sarcoidosis the T4/T8 quotient was checked in broncho-alveolar lavage (BAL) for its informative value with regard to activity and prognosis of the disease. In asymptomatic patients with x-ray type I and normal lung function, in radiological remissions of x-ra
Blockade of human immunodeficiency virus type 1 production in CD4+ T cells by an intracellular CD4 expressed under control of the viral long terminal repeat.: Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2695-9. Unique Identifier : AIDSLINE MED/93219350; Buonocore L; Rose JK; Department of Pathology, Yale University School of Medicine, New; Haven, CT 06510.; A retroviral vector was constructed in which a gene encoding a mutated soluble CD4 protein that is retained in the endoplasmic reticulum (sCD4-KDEL) is expressed under control of human immunodeficiency virus type 1 (HIV-1) regulatory elements. HIV-1 infection of a human T-cell line transduced with this vector led to i
Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor.: Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2700-4. Unique Identifier : AIDSLINE MED/93219351; Fantini J; Cook DG; Nathanson N; Spitalnik SL; Gonzalez-Scarano F; Department of Neurology, University of Pennsylvania Medical; Center, Philadelphia 19104-6146.; The gastrointestinal tract plays a major role in the pathogenesis and pathophysiology of infection by the type 1 human immunodeficiency virus (HIV-1). It is a potential route for viral entry and it is the site of a number of complications, including both opportunistic infections and a primary HIV-induced enteropathy.
The envelope glycoprotein of human immunodeficiency virus type 1 stimulates release of neurotoxins from monocytes.: Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2769-73. Unique Identifier : AIDSLINE MED/93219365; Giulian D; Wendt E; Vaca K; Noonan CA; Department of Neurology, Baylor College of Medicine, Houston, TX; 77030.; Mononuclear phagocytes infected with human immunodeficiency virus 1 (HIV-1) produce soluble factors that kill neurons in culture. To define the molecular events that lead to neuron killing, HIV-1 proteins were tested for the ability to trigger release of neurotoxins from human monocytes and lymphocytes. None of the re
Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses.: Proc Natl Acad Sci U S A. 1993 Apr 1;90(7):2984-8. Unique Identifier : AIDSLINE GENBANK/L11891; Gill RK; Christakos S; Department of Biochemistry and Molecular Biology, University of; Medicine and Dentistry-New Jersey Medical School, Newark 07103.; We have examined the 5 flanking region of the mouse calbindin-D28k gene and identified a 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3]-responsive element by deletion mutant analysis of the native promoter as well as by studies with a heterologous thymidine kinase (TK) promoter. The segment between residues -200 and -169 wa
Teen Peer Outreach-Street Work Project: HIV prevention education for runaway and homeless youth.: Public Health Rep. 1993 Mar-Apr;108(2):150-5. Unique Identifier : AIDSLINE MED/93219506; Podschun GD; College of Health and Human Services, San Diego State University,; CA.; Each year, there are approximately 2 million homeless and runaway youths in the United States . On any given night, there are 1,000 homeless youngsters living on the streets of San Diego, CA. Homeless young people are commonly involved in one or more of the following activities that pla
FDA warns frequent yeast infections could be early sign of HIV [news]: Public Health Rep. 1993 Mar-Apr;108(2):259. Unique Identifier : AIDSLINE MED/93219521
[Comparative study of pneumococcal bacteremia in patients with and without HIV infection (see comments)]: Rev Clin Esp. 1993 Jan;192(1):21-4. Unique Identifier : AIDSLINE MED/93219590; Roca V; Perez-Cecilia E; Santillana T; Romero J; Picazo JJ; Departamento de Medicina Interna, Hospital Universitario San; Carlos, Madrid.; A retrospective study of bacteriemias due to S. pneumoniae in adults is performed, from all the cases observed in our hospital during the 1989-1990 period. We compare the clinical characteristics of the disease depending if the affected patients were infected or not by the human immunodeficiency virus (HIV). In the co
[Pulmonary cavitations caused by Pneumocystis carinii in an HIV+ patient (letter; comment)]: Rev Clin Esp. 1993 Jan;192(1):51-2. Unique Identifier : AIDSLINE MED/93219600; Brea Hernando AJ; Mosquera Lozano JD; Garcia Moreno V; Saralegui Reta I
[Guillain-Barre syndrome as initial manifestation of human immunodeficiency virus infection (letter)]: Rev Clin Esp. 1993 Jan;192(1):52. Unique Identifier : AIDSLINE MED/93219601; Peris Cuello X; Salgado Remigio A; Gomez Jimenez J; Peracaula Picart R
[Tuberculous pericarditis as the first manifestation of AIDS. The indication for diagnostic pericardiocentesis (letter) (see comments)]: Rev Clin Esp. 1993 Feb;192(3):150-1. Unique Identifier : AIDSLINE MED/93219624; Supervia A; Campodarve I; Shaath M; Mellibovsky L; Cladellas M; Bruguera J
[A pulmonary abscess due to Rhodococcus equi in an AIDS patient (letter)]: Rev Clin Esp. 1993 Feb;192(3):152. Unique Identifier : AIDSLINE MED/93219626; Gazquez I; Garcia Gonzalez M; Pena JM; Rubio M; Nogues A
[HIV seroprevalence in pregnant women: knowledge of women of the tests used]: Rev Epidemiol Sante Publique. 1993;41(1):99-101. Unique Identifier : AIDSLINE MED/93219646; du Mazaubrun C; Paris-Llado J; Couturier E; Brossard Y; Larsen C; Brunet JB; Breart G; Unite de recherches epidemiologique sur la sante des femmes; et des enfants, U 149-INSERM, Paris.
DOD to single out MicroGeneSys vaccine [news]: Science. 1993 Apr 2;260(5104):19. Unique Identifier : AIDSLINE MED/93219826
Incentives for physicians to treat HIV-seropositive patients: results of a statewide survey.: South Med J. 1993 Apr;86(4):403-8. Unique Identifier : AIDSLINE MED/93219856; Samuels ME; Shi L; Stoskopf CH; Richter DL; Baker SL; Sy FS; Department of Health Administration, School of Public Health,; University of South Carolina, Columbia 29208.; We asked primary care physicians in South Carolina about their knowledge, attitudes, and beliefs regarding patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) and the services they provide for these patients. In support of an effort to develop more effective state p
Dilated cardiomyopathy as an early and rapidly progressive presentation in a woman with acquired immunodeficiency syndrome.: South Med J. 1993 Apr;86(4):465-8. Unique Identifier : AIDSLINE MED/93219870; Noreuil TO; Dinh HA; Department of Medicine, University of Arkansas for Medical; Sciences, Little Rock.; Cardiac disease associated with AIDS is common and is manifested by a variety of lesions. With the advances in therapy for common opportunistic infections, AIDS-associated cardiac abnormalities will play a prominent role in morbidity and mortality. This case illustrates a rapidly progressive and fetal course of AIDS-a
Immune activation in human rabies.: Trans R Soc Trop Med Hyg. 1993 Jan-Feb;87(1):106-8. Unique Identifier : AIDSLINE MED/93220095; Hemachudha T; Panpanich T; Phanuphak P; Manatsathit S; Wilde H; World Health Organization Collaborating Centre for Research on; Rabies Pathogenesis and Prevention, Queen Saovabha Memorial; Institute, Bangkok, Thailand.; Serum cytokines were compared by enzyme-linked immunosorbent assay among (i) 28 patients with rabies, (ii) 13 patients with non-fatal encephalitis due to other viruses, (iii) 16 patients with immune-mediated neurological diseases, and (iv) 15 patients with non-viral central nervous system infections and non-HTLV-I pro
The development and validation of a simple antigen detection ELISA for Plasmodium falciparum malaria.: Trans R Soc Trop Med Hyg. 1993 Jan-Feb;87(1):29-31. Unique Identifier : AIDSLINE MED/93220105; Taylor DW; Voller A; Department of Biology, Georgetown University, Washington, DC; 20057-1028.; A double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) is described for the detection of Plasmodium falciparum antigen. The test is based on an immunoglobulin (Ig) M capture monoclonal antibody on the solid phase and an IgG monoclonal antibody conjugated to peroxidase. The simple test takes about 2.5 h t
Pneumocystis carinii pneumonia and tuberculosis in Tanzanian patients infected with HIV.: Trans R Soc Trop Med Hyg. 1993 Jan-Feb;87(1):55-6. Unique Identifier : AIDSLINE MED/93220114; Atzori C; Bruno A; Chichino G; Gatti S; Scaglia M; Department of Infectious Diseases, IRCCS Policlinico S. Matteo,; Pavia, Italy.
Two cases of HIV-associated cryptococcosis due to the variety gattii in Rwanda.: Trans R Soc Trop Med Hyg. 1993 Jan-Feb;87(1):63-4. Unique Identifier : AIDSLINE MED/93220117; Bogaerts J; Taelman H; Batungwanayo J; Van de Perre P; Swinne D; Department of Microbiology, Centre Hospitalier de Kigali, Rwanda.
HIV-Leishmania co-infections in Italy: serological data as an indication of the sequence of acquisition of the two infections.: Trans R Soc Trop Med Hyg. 1993 Jan-Feb;87(1):94-6. Unique Identifier : AIDSLINE MED/93220132; Gradoni L; Scalone A; Gramiccia M; Laboratorio di Parassitologia, Istituto Superiore di Sanita,; Roma, Italy.; Twenty-two sera from visceral leishmaniasis (VL) patients with human immunodeficiency virus (HIV) infection (50% with the acquired immune deficiency syndrome) were examined for anti-Leishmania immunoglobulin G (IgG) antibodies and compared with 35 sera from VL patients without HIV (controls). Significant titres of spe
[CORSET, experience with a new method of graft saving tissue replacement in large soft tissue defects]: Unfallchirurgie. 1993 Feb;19(1):16-26. Unique Identifier : AIDSLINE MED/93220191; Inglis R; Windolf J; Pannike A; Klinikum der Johann-Wolfgang-Goethe-Universitat,; Unfallchirurgische Klinik, Frankfurt am Main.; Following the proposal of Oedekoven we investigated the method of continuous and rapid skin enlargement by dynamic traction (which we named the CORSET-method) at the border of wounds, applied through elastic silicon rubber bands. Since March 1992 we operated more than 20 patients. By means of the rubber bands mentione
[The emergence of viruses resistant to antiviral agents: a new challenge]: Union Med Can. 1993 Jan-Feb;122(1):31-6. Unique Identifier : AIDSLINE MED/93220200; Boivin G; Division of clinical microbiology, University of Minnesota; Medical School.; Recent use of antiviral drugs and the increase in the number of viral infections in immunocompromised hosts have led to the development of viral resistance. In this paper, the author reviews the antiviral drugs on the market, the antiviral susceptibility tests and presents a review of the literature concerning infecti
[Tuberculosis: a new disease. An interview with Dr. Alix Adrien]: Union Med Can. 1993 Jan-Feb;122(1):6-12. Unique Identifier : AIDSLINE MED/93220204; Adrien A
Prevalence and incidence of left ventricular dysfunction in patients with human immunodeficiency virus infection.: Am J Cardiol. 1993 Apr 15;71(11):955-8. Unique Identifier : AIDSLINE MED/93220638; Herskowitz A; Vlahov D; Willoughby S; Chaisson RE; Schulman SP; Neumann DA; Baughman KL; Department of Medicine, School of Public Health and Hygiene,; Johns Hopkins Medical Institutions, Baltimore, Maryland.; The prevalence and incidence of left ventricular (LV) dysfunction was examined in patients infected with the human immunodeficiency virus (HIV). Sixty-nine randomly selected patients diagnosed with HIV infection who were followed in HIV clinics were prospectively evaluated by 2-dimensional echocardiography. Mean follo
Mechanisms of proteinuria in noninflammatory glomerular diseases.: Am J Kidney Dis. 1993 Apr;21(4):347-62. Unique Identifier : AIDSLINE MED/93220670; Savin VJ; Department of Medicine, University of Kansas Medical Center,; Kansas City 66160-7382.; Neither the initiating factors nor the proximate causes of injury that produce proteinuria in nephrotic syndrome have been clearly defined. Immune mechanisms have been postulated in minimal-change nephrotic syndrome (MCNS), focal segmental glomerular sclerosis (FSGS), and glomerular sclerosis associated with human imm
The health of African Americans: special emphasis on kidney disease.: Am J Kidney Dis. 1993 Apr;21(4 Suppl 1):3-5. Unique Identifier : AIDSLINE MED/93220694; Mason JO
The AIDS dilemma [editorial]: Am J Sports Med. 1993 Mar-Apr;21(2):169. Unique Identifier : AIDSLINE MED/93220771; Leach RE
A review of allograft processing and sterilization techniques and their role in transmission of the human immunodeficiency virus.: Am J Sports Med. 1993 Mar-Apr;21(2):170-5. Unique Identifier : AIDSLINE MED/93220772; Asselmeier MA; Caspari RB; Bottenfield S; Orthopaedic Research of Virginia, Richmond.; Human immunodeficiency virus (HIV) infection via vascular organ and tissue transplantation is well documented. The majority of these transmissions occurred before the development of HIV antibody testing, which is now a routine screening tool used before organ and tissue procurement and transplantation. There exists wh
Calculated risk of human immunodeficiency virus infection in anesthesiologists [letter; comment]: Anesth Analg. 1993 Apr;76(4):912-3. Unique Identifier : AIDSLINE MED/93220931; Berry AJ
Risk of HIV infection [letter; comment]: Anesth Analg. 1993 Apr;76(4):913-4. Unique Identifier : AIDSLINE MED/93220932; Greene ES
HIV-1 and the lung. Infectivity, pathogenic mechanisms, and cellular immune responses taking place in the lower respiratory tract.: Am Rev Respir Dis. 1993 Apr;147(4):1038-49. Unique Identifier : AIDSLINE MED/93221002; Agostini C; Trentin L; Zambello R; Semenzato G; Padua University School of Medicine, Italy.
Quantitative bacillary response to treatment in HIV-associated pulmonary tuberculosis.: Am Rev Respir Dis. 1993 Apr;147(4):958-61. Unique Identifier : AIDSLINE MED/93221035; Brindle RJ; Nunn PP; Githui W; Allen BW; Gathua S; Waiyaki P; Kenya Medical Research Institute, Nairobi.; A group of 122 patients with culture-proven pulmonary tuberculosis were recruited to examine the concentrations of Mycobacterium tuberculosis in sputum and the relationship to HIV-1 antibody status. They were followed for up to 28 days from the start of antituberculous chemotherapy to assess the early bacillary respon
AORN supports HIV testing, counseling [news]: AORN J. 1993 Apr;57(4):820. Unique Identifier : AIDSLINE MED/93221130
Let's put our fear of HIV in proper perspective [editorial] [see comments]: AORN J. 1993 Apr;57(4):822, 824. Unique Identifier : AIDSLINE MED/93221131; Giordano BP
AIDS-related bronchopleural fistula [letter; comment]: Ann Thorac Surg. 1993 Apr;55(4):1048. Unique Identifier : AIDSLINE MED/93221280; Walker WA; Pate JW; Amundson D; Kennedy C
Enzymatic labeling of biologically active envelope glycoprotein gp120 of HIV-1.: Biochem Biophys Res Commun. 1993 Mar 31;191(3):1055-65. Unique Identifier : AIDSLINE MED/93221467; Berkower I; Murphy D; Division of Allergenics and Parasitology Center for Biologics,; FDA, NIH Campus, Bethesda, MD 20892.; We have found that the envelope glycoprotein gp120 of HIV-1 can be modified extensively by enzymatic oxidation of oligosaccharide chains without diminishing binding to its natural receptor, CD4. Using affinity purified galactose oxidase, over 20 sites per gp120 molecule were converted to chemically reactive aldehydes,
Kinetic assay for HIV proteinase subunit dissociation.: Biochem Biophys Res Commun. 1993 Mar 31;191(3):998-1003. Unique Identifier : AIDSLINE MED/93221548; Kuzmic P; University of Wisconsin, School of Pharmacy, Madison 53706.; The kinetics and thermodynamics of the monomer--dimer equilibrium for HIV-1 proteinase are investigated in a concentration jump experiment, at a concentration of the substrate that is substantially lower than the Michaelis constant. Under these conditions the substrate-induced stabilization of the active dimer is supp
Aromatic diamidines are reversible inhibitors of porcine kidney diamine oxidase.: Biochem Pharmacol. 1993 Mar 24;45(6):1355-7. Unique Identifier : AIDSLINE MED/93221570; Cubria JC; Balana Fouce R; Alvarez-Bujidos ML; Negro A; Ortiz AI; Ordonez D; Departamento de Fisiologia, Farmacologia y Toxicologia,; Facultad de Veterinaria, Universidad de Leon, Spain.; The inhibitory ability of aromatic diamidines has been studied on porcine kidney diamine oxidase. The reversibility of drug-protein interactions has been tested by means of exhaustive dialysis experiments, showing in all cases a reversible binding pattern. Ki values obtained by means of Lineweaver-Burk plots were: sti
The safety of Bacille Calmette-Guerin vaccination in HIV infection and AIDS [editorial]: AIDS. 1993 Feb;7(2):149-57. Unique Identifier : AIDSLINE MED/93221717; Weltman AC; Rose DN
HIV wasting syndrome in the United States.: AIDS. 1993 Feb;7(2):183-8. Unique Identifier : AIDSLINE MED/93221721; Nahlen BL; Chu SY; Nwanyanwu OC; Berkelman RL; Martinez SA; Rullan JV; Division of HIV/AIDS, Centers for Disease Control, Atlanta,; Georgia 30333.; OBJECTIVE: To describe the characteristics of individuals > or = 13 years of age with HIV wasting syndrome in the United States and US territories. DESIGN: Retrospective review of national AIDS case surveillance data. METHODS: Data for the 147,225 individuals with AIDS reported to the
Clinical correlates of in vitro HIV-1 resistance ot zidovudine. Results of the Multicentre Canadian AZT Trial.: AIDS. 1993 Feb;7(2):189-96. Unique Identifier : AIDSLINE MED/93221722; Montaner JS; Singer J; Schechter MT; Raboud JM; Tsoukas C; O'Shaughnessy M; Ruedy J; Nagai K; Salomon H; Spira B; et al; AIDS Research Programme, St Paul's Hospital, University of; British Columbia, Vancouver, Canada.; OBJECTIVE: To describe the rate of development of in vitro HIV resistance to zidovudine (ZDV) and its prognostic implications within the Multicentre Canadian AZT Trial (MCAT). METHODS: HIV-infected subjects in Centers for Disease Control (CDC) stages
Comparison of two dose regimens of zidovudine in an open, randomized, multicentre study for severe HIV-related thrombocytopenia.: AIDS. 1993 Feb;7(2):209-12. Unique Identifier : AIDSLINE MED/93221724; Landonio G; Cinque P; Nosari A; Gafa S; Rizzo F; Coen M; Tirelli U; Caggese L; di Luzio Paparatti U; Lazzarin A; ITP Study Group, Ospedale Niguarda Ca Granda, Milano, Italia.; OBJECTIVE: To compare the effect of two dose regimens of zidovudine in the treatment of severe HIV-related thrombocytopenia (TP). DESIGN: Eighty-four patients with severe HIV-related TP and platelet counts
Intestinal parasites and HIV infection in Tanzanian children with chronic diarrhea.: AIDS. 1993 Feb;7(2):213-21. Unique Identifier : AIDSLINE MED/93221725; Cegielski JP; Msengi AE; Dukes CS; Mbise R; Redding-Lallinger R; Minjas JN; Wilson ML; Shao J; Durack DT; Department of Medicine, Duke University Medical Center, Durham,; North Carolina 27710.; OBJECTIVE: To determine whether specific intestinal parasites are associated with HIV infection in Tanzanian children with chronic diarrhea. DESIGN: A prospective, cross-sectional study. SETTING: Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania. SUBJECTS: All children aged 15 months to 5 years
Elevated plasma levels of vasoactive intestinal peptide in AIDS patients with refractory idiopathic diarrhoea. Effects of treatment with octreotide.: AIDS. 1993 Feb;7(2):223-6. Unique Identifier : AIDSLINE MED/93221726; Manfredi R; Vezzadini P; Costigliola P; Ricchi E; Fanti MP; Chiodo F; Istituto Malattie Infettive, University of Bologna, Italy.; OBJECTIVE: To evaluate plasma levels of vasoactive intestinal peptide (VIP) in AIDS patients with refractory idiopathic diarrhoea, and to assess the role of treatment with octreotide. PATIENTS: Three AIDS patients were evaluated for severe watery diarrhoea of 2-6 months duration, which was complicated by weight loss,
Diagnosis of visceral leishmaniasis in HIV-infected individuals using peripheral blood smears.: AIDS. 1993 Feb;7(2):227-30. Unique Identifier : AIDSLINE MED/93221727; Martinez P; de la Vega E; Laguna F; Soriano V; Puente S; Moreno V; Sentchordi MJ; Garcia-Aguado C; Gonzalez-Lahoz J; Seccion de Hematologia y Bioquimica, Instituto de Salud Carlos; III, Madrid, Spain.; OBJECTIVE: To compare the clinical and laboratory features of visceral leishmaniasis (kala-azar) in HIV-infected and non-infected subjects, and to determine the presence of Leishmania amastigotes in circulating leukocytes using peripheral blood smears. PATIENTS: Twenty-eight HIV-infected and six HIV-negative adult pat
The treatment-free incubation period of AIDS in a cohort of homosexual men.: AIDS. 1993 Feb;7(2):231-9. Unique Identifier : AIDSLINE MED/93221728; Hendriks JC; Medley GF; van Griensven GJ; Coutinho RA; Heisterkamp SH; van Druten HA; Department of Public Health, Municipal Health Service, Amsterdam,; The Netherlands.; OBJECTIVE: The treatment-free incubation period distribution was estimated from data obtained from a cohort of homo/bisexual men in Amsterdam. DESIGN: Participants in a cohort study that started in Amsterdam at the end of 1984 were seen at 3- or 6-monthly intervals. The analysis excluded time since the start of zidovu
Three-year neuropsychological follow-up in a selected group of HIV-infected homosexual/bisexual men.: AIDS. 1993 Feb;7(2):241-5. Unique Identifier : AIDSLINE MED/93221729; Mauri M; Sinforiani E; Muratori S; Zerboni R; Bono G; Neuro AIDS-Unit, IRCCS C. Mondino, University of Pavia, Italy.; OBJECTIVE: To evaluate changes in cognition in a selected group of asymptomatic homosexual/bisexual men over a 3-year period. PATIENTS AND METHODS: Sixty HIV-infected (Centers for Disease Control stage II) subjects and 60 controls (individually matched for age and years in education) were administered neuropsychologic
Evaluation of a cognitive-behavioural intervention for HIV prevention among injecting drug users.: AIDS. 1993 Feb;7(2):247-56. Unique Identifier : AIDSLINE MED/93221730; Baker A; Heather N; Wodak A; Dixon J; Holt P; National Drug and Alcohol Research Centre, University of New; South Wales, Sydney, Australia.; OBJECTIVE: To evaluate the effectiveness of relapse prevention (RP) and brief intervention (BI) in reducing HIV risk-taking behaviours among injecting drug users (IDU) enrolled in methadone programmes. The hypotheses tested were: (1) that a six-session RP programme would be more effective in reducing HIV risk-taking b
Sustaining safe sex: a longitudinal study of a sample of homosexual men.: AIDS. 1993 Feb;7(2):257-63. Unique Identifier : AIDSLINE MED/93221731; Kippax S; Crawford J; Davis M; Rodden P; Dowsett G; School of Behavioural Sciences, Macquarie University, Sydney, New; South Wales, Australia.; OBJECTIVE: TO assess the maintenance of safe sexual practice. (We use the term safe sex throughout the paper, since safe is the term adopted by the Australian National Committee on AIDS). DESIGN: Maintenance was assessed by comparing sexual behaviour with both regular and casual partners reported in a 1986/1987 su
The effectiveness of condom use in heterosexual prostitution in The Netherlands.: AIDS. 1993 Feb;7(2):265-9. Unique Identifier : AIDSLINE MED/93221732; de Graaf R; Vanwesenbeeck I; van Zessen G; Straver CJ; Visser JH; The Netherlands Institute of Social Sexological Research (NISSO),; Utrecht.; OBJECTIVES: To assess the extent to which condoms are used effectively in commercial heterosexual intercourse. Data on the number of condoms that had broken or slipped off, the sexual technique during which this had occurred and the perceived cause of failure were collected. The use of non-water-soluble lubricants and
The effects of post-test counselling on condom use among prostitutes in The Gambia.: AIDS. 1993 Feb;7(2):271-3. Unique Identifier : AIDSLINE MED/93221733; Pickering H; Quigley M; Pepin J; Todd J; Wilkins A; Medical Research Council, Banjul, The Gambia.; OBJECTIVES: To determine the effect of counselling on condom use by prostitutes. DESIGN: Cohort study. SETTING: Field-based study in The Gambia . PARTICIPANTS: Thirty-one (12 HIV-positive and 19 HIV-negative) prostitutes. INTERVENTIONS: Post-test HIV counselling. MAIN OUTCOME MEASUR
Estimating the seroincidence of HIV-1 in the general adult population in Kigali, Rwanda.: AIDS. 1993 Feb;7(2):275-7. Unique Identifier : AIDSLINE MED/93221734; Bucyendore A; Van de Perre P; Karita E; Nziyumvira A; Sow I; Fox E; Rwanda National AIDS Control Program, Ministry of Health, Kigali.; OBJECTIVE: To estimate the seroincidence of HIV-1 infection in the general adult population of Kigali, Rwanda . DESIGN: Repeated standardized cross-sectional studies. SETTING: Two urban prenatal clinics. PATIENTS: A total of 4486 consecutive pregnant women consulting in 1989 and 199
Safer sex maintenance among gay men: are we moving in the right direction? [editorial]: AIDS. 1993 Feb;7(2):279-80. Unique Identifier : AIDSLINE MED/93221735; Davies PM
Safer sex among gay men: what is the ultimate goal? [editorial]: AIDS. 1993 Feb;7(2):281-2. Unique Identifier : AIDSLINE MED/93221736; Ekstrand M; Stall R; Kegeles S; Hays R; DeMayo M; Coates T
HIV seropositivity of blood donations in Spain: a 4-year surveillance (1988-1991). The HIV Blood Donations Study Group [letter]: AIDS. 1993 Feb;7(2):283-4. Unique Identifier : AIDSLINE MED/93221737; de Andres-Medina R; Perez-Alvarez L; Najera-Morrondo R
Concurrent partners and the results of the Uganda Rakai project [letter; comment]: AIDS. 1993 Feb;7(2):286-8. Unique Identifier : AIDSLINE MED/93221740; Hudson CP
Recurrent Kawasaki disease associated with co-infection with parvovirus B19 and HIV-1 [letter]: AIDS. 1993 Feb;7(2):288-90. Unique Identifier : AIDSLINE MED/93221741; Nigro G; Pisano P; Krzysztofiak A
Zidovudine-responsive pure red cell aplasia as initial manifestation of HIV infection [letter]: AIDS. 1993 Feb;7(2):290-1. Unique Identifier : AIDSLINE MED/93221742; Dervenoulas JG; Gogas HJ; Lazanas MC; Megalou AA; Raptis SA
Antibodies to natural killer cells in HIV-infected patients [letter]: AIDS. 1993 Feb;7(2):291-2. Unique Identifier : AIDSLINE MED/93221743; Muller C; Kukel S; Bauer R
Spermicides: anti-HIV activity and cytotoxicity in vitro [letter]: AIDS. 1993 Feb;7(2):293-5. Unique Identifier : AIDSLINE MED/93221745; Salole EG; Shepherd AJ
Survival of HIV-infected Brazilians: a model based on the World Health Organization staging system [letter]: AIDS. 1993 Feb;7(2):295-6. Unique Identifier : AIDSLINE MED/93221746; Lima LA; May SB; Perez MA; Schechter M
Statistics from the World Health Organization.: AIDS. 1993 Feb;7(2):297-8. Unique Identifier : AIDSLINE MED/93221747
A critical analysis of human immunodeficiency virus transmission using human cartilage allografts.: Eur Arch Otorhinolaryngol. 1993;250(1):55-8. Unique Identifier : AIDSLINE MED/93221850; Bujia J; Pitzke P; Wilmes E; Hammer C; Gurtler L; Department of Otorhinolaryngology, Ludwig Maximilians University; Munich, Germany.; Allogeneic cartilage represents an important source of tissue for reconstructive surgery in the head and neck. The use of allografts is now being discussed because of the possible transmission of the human immunodeficiency virus (HIV). The receptor for HIV in most cell types is the CD-4 molecule. Since cartilage is a
[First aid 30,000 feet high (interview by Siv Barstad)]: J Sykepleien. 1993 Jan 19;81(1):14-6. Unique Identifier : AIDSLINE MED/93221938; Rosenlund S; Roe J
[Asia: front-line country in the HIV epidemic (news)]: J Sykepleien. 1993 Jan 19;81(1):20. Unique Identifier : AIDSLINE MED/93221942
[Special hospital stifles guest patients' arrangement. Sunnaas struggles (interview by Siv Barstad)]: J Sykepleien. 1993 Jan 19;81(1):7-8. Unique Identifier : AIDSLINE MED/93221947; Lunde O
Avoiding the risk of needlestick injuries.: Nurs Stand. 1993 Jan 13-19;7(17):25-8. Unique Identifier : AIDSLINE MED/93222029; Ingram J; It is dangerous not to recap used needles, yet it can be equally dangerous to recap them. For each of us in the health sector, the prevention of needlestick injury (NSI) should be an everyday objective. This article discusses the risks associated with NSIs and examines whether current recommendations are being ignored
Farewell to a special nurse [editorial]: Nurs Stand. 1993 Jan 13-19;7(17):3. Unique Identifier : AIDSLINE MED/93222030; Casey N
Ethics: nursing care of gay and lesbian patients.: Nurs Stand. 1993 Jan 13-19;7(17):34-7. Unique Identifier : AIDSLINE MED/93222032; Platzer H; Work currently being undertaken by the Royal College of Nursing s Lesbian and Gay Nursing Issues Working Party has revealed evidence of prejudice towards, and discrimination against, lesbian and gay patients by members of the nursing and medical professions. In addition, there are instances when the specific nursing n
Nursing, HIV & AIDS: AVERT funded project.: Nurs Stand. 1993 Jan 13-19;7(17):38-9. Unique Identifier : AIDSLINE MED/93222033; Scott C; October 1991 saw the start of a two-year national investigation into the nursing care and treatment of people with HIV/AIDS. The project is based in the Daphne Heald Research Unit at the Royal College of Nursing and is funded by the AIDS Education and Research Trust (AVERT). The aim is to gather information on current
HIV surveys should be treated with caution [news]: Nurs Stand. 1993 Jan 13-19;7(17):6. Unique Identifier : AIDSLINE MED/93222039
Tributes flood in for Richard Wells--'a very special man' [news]: Nurs Stand. 1993 Jan 13-19;7(17):6. Unique Identifier : AIDSLINE MED/93222040
Inhibitor binding to the Phe53Trp mutant of HIV-1 protease promotes conformational changes detectable by spectrofluorometry.: Biochemistry. 1993 Apr 13;32(14):3557-63. Unique Identifier : AIDSLINE MED/93222153; Rodriguez EJ; Debouck C; Deckman IC; Abu-Soud H; Raushel FM; Meek TD; Department of Medicinal Chemistry, SmithKline Beecham; Pharmaceuticals, King of Prussia, Pennsylvania 19406.; HIV-1 protease contains two identical, conformationally mobile loops, known as flaps, which form in part the binding pockets for substrates and inhibitors. We have constructed a site-specific mutant of the protease in which residues Phe-53 and Phe-153 at the end of the flaps have been mutated to Trp residues, in order
Laws affect treatment of HIV patients.: Natl Med Leg J. 1993 2nd Quarter;4(2):3. Unique Identifier : AIDSLINE MED/93222380; Ziemba TM
[A case of AIDS in primary care (letter; comment)]: Aten Primaria. 1993 Mar 15;11(4):202-3. Unique Identifier : AIDSLINE MED/93222449; Arto Serrano A; Royo Serrano M
Nutrition behavior of malnourished HIV-infected patients and intensified oral nutritional intervention.: Nutrition. 1993 Jan-Feb;9(1):43-4. Unique Identifier : AIDSLINE MED/93222555; Burger B; Ollenschlager G; Schrappe M; Stute A; Fischer M; Wessel D; Schwenk A; Diehl V; Department of Internal Medicine, University Hospital, Cologne,; Germany.; Malnutrition and cachexia are characteristic symptoms of human immunodeficiency virus (HIV)-1 infection and AIDS. To identify risk situations that might affect nutritional behavior and status and to evaluate the therapeutic effect of an intensified oral nutritional intervention, we analyzed 81 consecutively treated ho
[The European study for counseling in HIV antibody testing in general practice: results of the German project section]: Gesundheitswesen. 1993 Feb;55(1 Suppl):46-52. Unique Identifier : AIDSLINE MED/93222573; Szecsenyi J; Niemetz I; Kochen MM; Abteilung Allgemeinmedizin, Universitat Gottingen.; General practitioners play an important role in counselling for HIV-Tests. There is little known yet about the background of the decision process which results in doing the HIV-test. The EUROSENTINEL-study on requests for HIV-testing started in 1990 and is in the meanwhile carried out in 7 sentinel-networks in six eur
Nurses remain ignorant over HIV/AIDS [editorial]: Br J Nurs. 1993 Feb 25-Mar 10;2(4):207. Unique Identifier : AIDSLINE MED/93222650; Cruickshanks M
Increased expression of interferon-gamma in hyperplastic lymph nodes from HIV-infected patients.: Clin Exp Immunol. 1993 Apr;92(1):100-5. Unique Identifier : AIDSLINE MED/93223295; Boyle MJ; Berger MF; Tschuchnigg M; Valentine JE; Kennedy BG; Divjak M; Cooper DA; Turner JJ; Penny R; Sewell WA; Centre for Immunology, St. Vincent's Hospital, Sydney, Australia.; Polyclonal B cell activation is characteristic of HIV infection and occurs in the presence of severe CD4+ lymphocyte depletion. In contrast, CD4+ lymphocytes are the dominant T cell in the reactive lymphoid tissues of patients not infected with HIV. In this study, lymph node biopsies from eight HIV-infected patients w
Use of probes and amplification techniques for the diagnosis and prognosis of human immunodeficiency virus (HIV-1) infections.: Diagn Microbiol Infect Dis. 1993 Feb;16(2):165-72. Unique Identifier : AIDSLINE MED/93223401; Arens M; Department of Pediatrics, Washington University School of; Medicine, St. Louis, MO 63110.; The recent development of nucleic acid amplification methodologies has markedly improved our ability to detect very low levels of specific nucleic acids. Amplification techniques have been combined with product detection systems that are designed for high throughput and are automatable. These developments are drastica
Dysphagia in dermatologic disease.: Dysphagia. 1993;8(2):85-90. Unique Identifier : AIDSLINE MED/93223517; Bubl R; Schon B; Dermatologische Klinik und Poliklinik, Technischen Universitat; Munchen, Germany.; Disorders of the oral cavity, pharynx, and esophagus may be found in some dermatologic diseases. The connective tissue diseases especially may be accompanied by dysphagia. Furthermore, some rare inflammatory and bullous dermatologic diseases can lead to esophageal disorders. Finally, some infectious and malignant dise
Benign intracranial hypertension associated with HIV infection.: Eur Neurol. 1993;33(3):191-2. Unique Identifier : AIDSLINE MED/93223736; Traverso F; Stagnaro R; Fazio B; Divisione di Neurologia, Ospedale di Sanremo, Italy.; We report the case of a 24-year-old woman with HIV-seropositivity, who developed a clinical picture of pseudotumor cerebri, an association not previously described. The patient improved with the use of acetazolamide. We suggest the possible existence of this disorder in HIV-infected patients with persistent headaches,
Health status of women in Florida.: Fla Nurse. 1993 Mar;41(3):11, 14. Unique Identifier : AIDSLINE MED/93223876; Amankwaa L
Report of Institute of Member Collective Bargaining [news]: Fla Nurse. 1993 Mar;41(3):16. Unique Identifier : AIDSLINE MED/93223878; Nilsson M
Combined treatments with interferon (alpha,beta) plus PGA1 to control early infection with HTLV-I in primary cord blood-derived mononuclear cells.: Int J Immunopharmacol. 1993 Feb;15(2):125-36. Unique Identifier : AIDSLINE MED/93224221; D'Onofrio C; Franzese O; Ricci F; Bonmassar E; Department of Experimental Medicine and Biochemical Sciences,; University of Rome Tor Vergata, Italy.; Interferon (IFN) alpha and beta can activate an antiviral and immunomodulating response in primary cord blood-derived mononuclear cells (CBMC) exposed to infection with Human T-cell Leukemia Virus type I (HTLV-I), resulting in partial inhibition of early infection in vitro. On the other hand, PGA1, a PGE1-derived cycl
Comparison of dideoxynucleoside drugs (DDI and zidovudine) and induction of hematopoietic toxicity using normal human bone marrow cells in vitro.: Int J Immunopharmacol. 1993 Feb;15(2):263-8. Unique Identifier : AIDSLINE MED/93224236; Gallicchio VS; Hughes NK; Tse KF; Department of Veterans Affairs, Veterans Administration Medical; Center, Lexington, Kentucky.; The drug zidovudine ( AZT ), a synthetic thymidine analog, has been used in the treatment of acquired immunodeficiency syndrome (AIDS). Clinical use of zidovudine has induced hematopoietic toxicity manifested by anemia, neutropenia and on occasion throm
[Intravenous drug addiction and the risk of HIV infection in Madrid in 1990]: Gac Sanit. 1993 Jan-Feb;7(34):2-11. Unique Identifier : AIDSLINE MED/93224259; Zunzunegui Pastor MV; Rodriguez Arenas MA; Sarasqueta Eizaguirre C; Centro Universitario de Salud Publica, Madrid.; As part of a multicenter WHO study on HIV infection among drug injectors, 472 intravenous drug users (IDUs) were interviewed, 240 recruited in the streets and 232 at drug treatment centers. The objectives of the study were to assess the prevalence of HIV infection among IDUs of Madrid, to identify factors associated w
Controlling the HIV epidemic among drug injectors.: Gac Sanit. 1993 Jan-Feb;7(34):41-4. Unique Identifier : AIDSLINE MED/93224263; Friedman SR; Des Jarlais DC; National Development and Research Institutes, Inc, New York.
Training for Iowa physicians.: Iowa Med. 1993 Apr;83(4):143-5. Unique Identifier : AIDSLINE MED/93224286; Crist L
[Prevalence of HIV infection among stable female partners of seropositive men]: Kansenshogaku Zasshi. 1993 Feb;67(2):95-101. Unique Identifier : AIDSLINE MED/93224782; Kimura S; Oka S; Shimada K; Department of Infectious Diseases and Applied Immunology,; University of Tokyo.; Prevalence of HIV transmission to female sexual partners of seropositive men is not known yet. In order to know the condition in Japan , 11 HIV-seropositive men (25-42 years old; mean +/- SD, 32.5 +/- 6.0) and their stable female partners (24-42 years old; mean +/- SD, 31.3 +/- 6.0)
The role of gp55 N-glycosylation in pathogenesis of Friend spleen focus-forming virus.: J Gen Virol. 1993 Apr;74 ( Pt 4):699-705. Unique Identifier : AIDSLINE MED/93224891; Rau S; Geyer R; Friedrich RW; Institute of Medical Virology, Justus Liebig University, Giessen,; Germany.; The product of the envelope gene (gp55) of Friend spleen focus-forming virus is responsible for the acute form of erythroleukaemia caused by this virus. In order to investigate the role that the four known N-linked carbohydrate side-chains of gp55 play in pathogenesis, we have inactivated the four N-glycosylation sign
In vitro non-productive infection of purified natural killer cells by the BRU isolate of the human immunodeficiency virus type 1.: J Gen Virol. 1993 Apr;74 ( Pt 4):725-31. Unique Identifier : AIDSLINE MED/93224894; Scott-Algara D; Vuillier F; Cayota A; Rame V; Guetard D; Moncany ML; Marasescu M; Dauguet C; Dighiero G; Unite d'ImmunoHematologie et d'ImmunoPathologie, Institut; Pasteur, Paris, France.; Highly purified natural killer (NK) cell lines and clones, displaying the typical phenotype, morphology and function and obtained from healthy blood donors, were infected in vitro with the BRU isolate of human immunodeficiency virus type 1 (HIV-1). There was no significant increase in reverse transcriptase activity an
Comparative study of the isolation of human immunodeficiency virus from the lung and peripheral blood of AIDS patients.: J Med Virol. 1993 Mar;39(3):196-9. Unique Identifier : AIDSLINE MED/93224909; Clarke JR; Williamson JD; Mitchell DM; Department of Medical Microbiology, St Mary's Hospital Medical; School, London, England.; HIV-1 proviral DNA was detected by the polymerase chain reaction (PCR) in leucocytes from the peripheral blood (PBL) and bronchoalveolar lavage (BAL) of 100% and 72%, respectively, of HIV-1 seropositive patients. Infective virus isolated by cocultivation was recovered from the PBL and BAL of 50% and 59% of individuals
Polymerase chain reaction-based detection of hepatitis D virus genome in patients infected with human immunodeficiency virus.: J Med Virol. 1993 Mar;39(3):214-8. Unique Identifier : AIDSLINE MED/93224912; Deny P; Lecot C; Jeantils V; Ovaguimian L; Krivitzky A; Brechot C; Service de Bacteriologie-Virologie, CHU Avicenne, Bobigny,; France.; The polymerase chain reaction (PCR) was used to detect hepatitis D (HD) viremia in patients infected with the human immunodeficiency virus (HIV). Nineteen (9%) of 206 such patients, unselected for liver disease or HBV infection, were found prospectively to be infected by HDV. Thirty-one anti-HIV-positive patients were
Small virus-like particles bud from the cell membranes of normal as well as HIV-infected human lymphoid cells.: J Med Virol. 1993 Mar;39(3):229-32. Unique Identifier : AIDSLINE MED/93224915; Dourmashkin RR; Bucher D; Oxford JS; Department of Medical Microbiology, London Hospital Medical; College, England.; Electron microscopy (EM) of cell sections showed cell associated virus-like particles (VLP), 50-60 nm in diameter, budding from the membrane of human lymphoid cells in culture. The particles had an envelope continuous with the cell membrane and a dense core that almost filled the particle. Particles 70-80 nm in diamet
Incidence of HTLV-I/II infection in seronegative high-risk individuals.: J Med Virol. 1993 Mar;39(3):260-5. Unique Identifier : AIDSLINE MED/93224920; Al B; Visser S; van den Hoek A; van Doornum G; Coutinho R; Huisman H; Department of Developmental Research, Central Laboratory of The; Netherlands Red Cross Blood Transfusion Service, Amsterdam.; The frequency of human T-cell lymphotropic virus types I and II (HTLV-I/II) polymerase chain reaction (PCR) reactivity was studied in two groups of high-risk individuals in Amsterdam: hard drug users and heterosexual outpatients of the sexual transmitted diseases (STD) clinic. Both groups were seronegative as determin
Chronic progressive spinocerebellar syndrome associated with antibodies to human T-lymphotropic virus type I: clinico-virological and magnetic resonance imaging studies.: J Neurol Sci. 1993 Mar;115(1):111-6. Unique Identifier : AIDSLINE MED/93224945; Kira J; Goto I; Otsuka M; Ichiya Y; Department of Neurology, Faculty of Medicine, Kyushu University,; Fukuoka, Japan.; The relationship between HTLV-I infection and the development of spinocerebellar degeneration (SCD) in adulthood was studied. The frequency of anti-HTLV-I antibodies among patients with SCD (8 of 43, 19%) was found to be higher than the seroprevalence rate in the northern part of Kyushu island (6%). All HTLV-I carrier
Intrathecal synthesis of interleukin-2 and soluble IL-2 receptor in asymptomatic HIV-1 seropositive individuals. Correlation with local production of specific IgM and IgG antibodies.: J Neurol Sci. 1993 Mar;115(1):117-22. Unique Identifier : AIDSLINE MED/93224946; Ciardi M; Sharief MK; Noori MA; Thompson EJ; Salotti A; Rossi F; Vullo V; Catania S; Sorice F; Cirelli A; Institute of Neurology, National Hospital for Neurology and; Neurosurgery, London, U.K.; The relationship between the interleukin-2 ( IL-2 ) system and the humoral response against human immunodeficiency virus type-I (HIV-1) is important in understanding the immune reaction before the development of AIDS. Levels of IL-2 and soluble IL-2 receptor (sIL-2R) in
Neurologic disorders affecting the lower extremities in HIV infection.: J Am Podiatr Med Assoc. 1993 Mar;83(3):156-60. Unique Identifier : AIDSLINE MED/93225107; Ramcharitar SI; Simpson DM; New York College of Podiatric Medicine, New York.
Sexual functioning in HIV+ and HIV- injected drug-using women.: J Sex Marital Ther. 1993 Spring;19(1):56-68. Unique Identifier : AIDSLINE MED/93225122; Meyer-Bahlburg HF; Nostlinger C; Exner TM; Ehrhardt AA; Gruen RS; Lorenz G; Gorman JM; el-Sadr W; Sorrell SJ; HIV Center for Clinical and Behavioral Studies, NYS Psychiatric; Institute, New York.; As part of a natural history study of HIV disease in injected drug users, 38 HIV positive (HIV+) asymptomatic or low-symptomatic women and 37 HIV negative (HIV-) women, mostly of minority inner-city background, underwent a comprehensive survey of sexual functioning. At study baseline, the sample as a whole showed a re
From the Centers for Disease Control and Prevention. False-positive serologic tests for human T-cell lymphotropic virus type I among blood donors following influenza vaccination, 1992.: JAMA. 1993 Apr 28;269(16):2076-8. Unique Identifier : AIDSLINE MED/93225182
[The indications for the use of gallium-67 scintigraphy]: Kaku Igaku. 1993 Feb;30(2):225-30. Unique Identifier : AIDSLINE MED/93225245; Kosuda S; Department of Radiology, National Defense Medical College,; Tokorozawa.; 67Ga citrate scanning has been widely used for imaging a variety of neoplasms and inflammatory lesions. In this review, indications and limitations of 67Ga scanning were briefly discussed, and four diseases, that is, sarcoidosis, malignant melanoma, malignant lymphoma and opportunistic infection in patients with AIDS,
[A multicenter study of infection with human immunodeficiency virus type-2 (HIV-2) in Spain (1991). The Spanish Group for the Study of HIV-2]: Med Clin (Barc). 1993 Apr 10;100(14):531-5. Unique Identifier : AIDSLINE MED/93225593; Soriano V; Gutierrez M; Tuset C; Martinez-Zapico R; Ortiz de Lejarazu R; Aguilera A; Codina G; Gonzalez A; Ulloa F; Leal M; et al; Servicio de Enfermedades Infecciosas, Instituto de Salud Carlos; III, Madrid.; BACKGROUND: To January 1991 thirteen cases of HIV-2 infection had been reported in Spain . Paradoxically, neighboring countries, i.e. France and Portugal , have
[Successful splenectomy in HIV thrombocytopenia]: Lakartidningen. 1993 Mar 24;90(12):1164-6. Unique Identifier : AIDSLINE MED/93225615; Bjorkholm B; Nilsson G; Norkrans G; Gustavsson B; Avdelningslakare, infektionskliniken, Goteborg.
[Post-infection HIV vaccination. More clinical trials are initiated in Sweden]: Lakartidningen. 1993 Mar 31;90(13):1243-5. Unique Identifier : AIDSLINE MED/93225626; Lennholm B
[The WHO statement on strategies of HIV vaccinations: field trials in developing countries should await studies of the effects]: Lakartidningen. 1993 Mar 31;90(13):1245-6. Unique Identifier : AIDSLINE MED/93225627; Lennholm B
HTLV-1 sequences in lymphocytes of a patient with non-tropical spastic tetraparesis and her asymptomatic husband.: New Microbiol. 1993 Jan;16(1):11-7. Unique Identifier : AIDSLINE MED/93225874; Manca N; Gelmi M; Mattioli F; Gargiulo F; Terlenghi L; Pirali F; Turano A; Institute of Microbiology, University of Brescia, Italy.; We describe a 65-year-old woman born and living in Northern Italy affected by non tropical spastic tetraparesis and her asymptomatic husband presenting HTLV-1 sequences in their lymphocytes detected by polymerase chain reaction (PCR). We discuss the significance of the case and the
Preliminary data on the establishment of permanent cell lines continuously producing HIV-1: factors affecting the transmissibility and adaptability of wild HIV-1 isolates.: New Microbiol. 1993 Jan;16(1):19-26. Unique Identifier : AIDSLINE MED/93225875; Di Stefano M; Fiore JR; Angarano G; Fico C; Grottola A; Pastore G; Clinic of Infectious Diseases, Policlinico Hospital, Bari, Italy.; This study examines some technical aspects of the transmission to and permanent adaptability in continuous cell lines of wild HIV-1 isolates. Three cell systems (the lymphocytic cell lines Molt-3 and H-9 and the monocytoid cell line U-937) and two transmission protocols (cell to cell and cell-free) were used. Two diff
The elevation of circulating platelets after IFN-alpha therapy in HIV-1 seropositive thrombocytopenic patients correlates with increased plasma levels of IL-6.: New Microbiol. 1993 Jan;16(1):27-34. Unique Identifier : AIDSLINE MED/93225876; Zauli G; Re MC; Gugliotta L; Furlini G; La Placa M; Institute of Microbiology, L. and A. Seragnoli, University of; Bologna, Italy.; In this study we evaluated the effect of recombinant interferon-alpha 2b (IFN-alpha 2b) therapy on the number of circulating platelets and interleukin-6 (IL-6) plasma levels in 12 human immunodeficiency virus type 1 (HIV-1) seropositive patients, affected by a severe and persistent thrombocytopenia. The levels of IL-6
Homosexually acquired gonorrhoea in Victoria, 1983-1991.: Med J Aust. 1993 Apr 5;158(7):450-3. Unique Identifier : AIDSLINE MED/93225904; Sherrard J; Forsyth JR; Microbiological Diagnostic Unit, University of Melbourne,; Parkville, Vic.; OBJECTIVE: To identify trends in the rate of gonorrhoea, particularly homosexually acquired infection. DESIGN: A retrospective descriptive study of records stored in a relational database. Records contain epidemiological, demographic and microbiological data of laboratory confirmed cases of gonorrhoea. SUBJECTS: Indiv
Adult T cell leukaemia lymphoma in a non-aboriginal Australian woman with no apparent risk factors.: Med J Aust. 1993 Apr 5;158(7):486-7. Unique Identifier : AIDSLINE MED/93225913; Tong MK; Wolf M; Juneja S; Department of Haematology and Medical Oncology, Peter MacCallum; Cancer Institute, Melbourne, Vic.; OBJECTIVE: To present a case of adult T cell leukaemia lymphoma (ATLL) in a non-Aboriginal Australian woman with no apparent risk factor. CLINICAL FEATURES: A 43-year-old Australian woman of European descent presented with a febrile illness associated with generalised lymphadenopathy and splenomegaly. INVESTIGATIONS:
HIV infection in rural Florida [letter; comment]: N Engl J Med. 1993 May 6;328(18):1351; discussion 1352. Unique Identifier : AIDSLINE MED/93226014; Potterat JJ
HIV infection in rural Florida [letter; comment]: N Engl J Med. 1993 May 6;328(18):1351-2. Unique Identifier : AIDSLINE MED/93226015; Whiteside ME
HIV infection in rural Florida [letter; comment]: N Engl J Med. 1993 May 6;328(18):1352. Unique Identifier : AIDSLINE MED/93226016; Brannon LA; Brock TC
Central nervous system toxoplasmosis in AIDS [letter; comment]: N Engl J Med. 1993 May 6;328(18):1353; discussion 1354. Unique Identifier : AIDSLINE MED/93226018; LaRocco A Jr; Sanders JW; Myers JW
Central nervous system toxoplasmosis in AIDS [letter; comment]: N Engl J Med. 1993 May 6;328(18):1353; discussion 1354. Unique Identifier : AIDSLINE MED/93226019; Manian FA
Central nervous system toxoplasmosis in AIDS [letter; comment]: N Engl J Med. 1993 May 6;328(18):1353-4. Unique Identifier : AIDSLINE MED/93226020; Bretagne S; Gray F; Costa JM
Cryptococcal meningitis after unusual exposures to birds [letter]: N Engl J Med. 1993 May 6;328(18):1354-5. Unique Identifier : AIDSLINE MED/93226021; Fessel WJ
AIDS patients are first in line [news]: Nature. 1993 Apr 22;362(6422):684. Unique Identifier : AIDSLINE MED/93226030; Swinbanks D
Retroviruses. One and one make four [news]: Nature. 1993 Apr 22;362(6422):697-8. Unique Identifier : AIDSLINE MED/93226039; Frank-Kamenetskii M
[A new chapter in the history of tuberculosis]: Ned Tijdschr Geneeskd. 1993 Mar 27;137(13):642-5. Unique Identifier : AIDSLINE MED/93226057; Vandenbroucke-Grauls CM; Verhoef J; Academisch Ziekenhuis, afd. Klinische Microbiologie en; Laboratorium voor Infectieziekten, Utrecht.
[Multiresistant tuberculosis: a new form of an old disease]: Ned Tijdschr Geneeskd. 1993 Mar 27;137(13):646-9. Unique Identifier : AIDSLINE MED/93226058; van Deutekom H; Braat MC; Coutinho RA; Sector Volksgezondheid en Milieu, afd. Tuberculosebestrijding,; Amsterdam.
Ventrolateral and dorsomedial somatosensory association cortex damage produces distinct somesthetic syndromes in humans [see comments]: Neurology. 1993 Apr;43(4):762-71. Unique Identifier : AIDSLINE MED/93226114; Caselli RJ; Section of Neurology, Mayo Clinic Scottsdale, AZ 85259.; Five somatosensory cortices have distinctive somatotopic representations, cytoarchitecture, and connectivity: primary somatosensory cortex (SI), ventrolateral association cortices (SII, SIII, and SIV), and dorsomedial association cortex (supplementary sensory area). Patients with focal lesions of ventrolateral (n = 5)
[Pregnancy in HIV positive women: psycho-emotional aspects. Study of 16 cases]: Minerva Ginecol. 1993 Jan-Feb;45(1-2):39-46. Unique Identifier : AIDSLINE MED/93226143; Morini A; Di Giusto M; Lambiasi A; Cantonetti G; Istituto di Clinica Ostetrica e Ginecologia, Universita degli; Studi di Roma La Sapienza, Roma.; The aim of this study was to analyse the day-to-day life of HIV-positive women during pregnancy and to assess the emotions deriving from their relations with the baby during the first few months of life. The study was carried out on a group of 16 HIV-positive women aged between 19 and 37 years old (mean age 27.3 years
Optimizing use of a hospital computer lab [interview]: Nurs Educ Microworld. 1993 Feb-Mar;7(3):20. Unique Identifier : AIDSLINE MED/93226265; Beauchea P
Metastatic placental lymphoma associated with maternal human immunodeficiency virus infection.: Obstet Gynecol. 1993 May;81(5 ( Pt 2)):856-7. Unique Identifier : AIDSLINE MED/93226322; Pollack RN; Sklarin NT; Rao S; Divon MY; Department of Obstetrics and Gynecology, Weiler Hospital, Albert; Einstein College of Medicine, Bronx, New York.; BACKGROUND: Pregnancy complicated by maternal human immunodeficiency virus (HIV) infection is increasing in frequency. This report describes a maternal malignancy associated with HIV infection that may complicate pregnancy. CASE: A 33-year-old primigravida was delivered by cesarean. Histologic examination of the place
HIV client education--what is your role?: Ohio Nurses Rev. 1993 Mar-Apr;68(2):6. Unique Identifier : AIDSLINE MED/93226342; Yarletts CL
Burkitt's lymphoma with mandible, intra-abdominal and renal involvement--initial presentation of HIV infection in a 4-year-old child.: Pediatr Radiol. 1993;23(1):76-7. Unique Identifier : AIDSLINE MED/93226460; Mukerji PK; Hilfer CL; St. Luke's-Roosevelt Hospital, Department of Radiology, New York,; NY 10025.; Burkitt s lymphoma of the jaw was first described as a jaw tumor occurring endemically in African children. We report a case of Burkitt s lymphoma in a child presenting with a painful jaw mass which proved to be Burkitt s lymphoma; renal involvement was also noted. The child was found to be HIV positive. Burkitt s may
Human gene therapy.: Pharmacotherapy. 1993 Mar-Apr;13(2):79-87. Unique Identifier : AIDSLINE MED/93226550; Gibaldi M; School of Pharmacy, University of Washington, Seattle 98195.
[Extrarenal clearance in HIV-infected patients with chronic kidney failure. Experience in a hospital center]: Presse Med. 1993 Jan 2-16;22(1):13-8. Unique Identifier : AIDSLINE MED/93226600; Fromentin L; Michel C; Viron B; Albert C; Mignon F; Service de Nephrologie, Hopital Tenon, Paris.; In HIV-infected patients with end-stage renal failure maintenance dialysis raises multiple problems, the most important of these being the quality and duration of life in these patients and the risk of contaminating other HIV negative patients under dialysis and/or members of the medical-nursing staff. In this study t
Influence of pentoxifylline on renal function in HIV-seropositive patients.: Ren Fail. 1993;15(2):181-8. Unique Identifier : AIDSLINE MED/93226777; Luke DR; Sarnoski TP; Bell N; Dennis S; Clinical Pharmacology Unit, Hoffman-La Roche Inc., Newark, New; Jersey 07112.; Pentoxifylline (PTX) has potential usefulness in HIV-seropositive patients due to its beneficial effects on renal function, its inhibitory effects on tumor necrosis factor alpha, and its vascular effects on microcirculatory disturbances. The present study prospectively evaluated the effects of multiple oral doses of P
Modification of lymphocyte and monocyte functional activity by polymorphonuclear neutrophils in HIV infection.: Scand J Immunol. 1993 Apr;37(4):459-67. Unique Identifier : AIDSLINE MED/93226969; Gabrilovich DI; Shepeleva GK; Serebrovskaya LV; Avdeeva LA; Pokrovsky VV; Laboratory of AIDS Epidemiology and Prevention, Central Institute; for Epidemiology, Moscow, Russia.; The aim of this study was to determine whether polymorphonuclear neutrophils (PMN) can modify the immune response in HIV cases. Supernatants of PMN (PMNS) from 33 HIV-infected patients (16 with lymphoadenopathy syndrome, 17 with AIDS-related complex) were tested for their influence on the functional activity of lympho
Early AZT takes a pounding in French-British 'Concorde' trial [news]: Science. 1993 Apr 9;260(5105):157. Unique Identifier : AIDSLINE MED/93227014; Cohen J
New AIDS research center to open [news]: Science. 1993 Apr 9;260(5105):158. Unique Identifier : AIDSLINE MED/93227015
MicroGeneSys: NIH faces down DOD [news]: Science. 1993 Apr 16;260(5106):288. Unique Identifier : AIDSLINE MED/93227035; Cohen J
AIDS research. Keystone's blunt message: 'it's the virus, stupid' [news] [published erratum appears in Science 1993 May 14;260(5110):879]: Science. 1993 Apr 16;260(5106):292-3. Unique Identifier : AIDSLINE MED/93227038; Cohen J
[Evolution of CD4 and CD8 lymphocyte subsets in HIV seronegative and seropositive hemophiliacs]: Sangre (Barc). 1993 Feb;38(1):5-11. Unique Identifier : AIDSLINE MED/93227133; Lorenzo JI; Molina R; Aznar JA; Unidad de Coagulopatias Congenitas, Hospital La Fe, Valencia.; PURPOSE: To asses the evolution over time of the CD4, CD8 and total lymphocyte counts in both HIV seronegative and HIV seropositive haemophiliacs. PATIENTS AND METHODS: A total of 124 haemophilic patients (77 HIV seropositive and 47 HIV seronegative) regularly controlled at our Hospital were studied. All patients have
[Hemophagocytic syndrome associated with histoplasmosis in the acquired immunodeficiency syndrome: description of 3 cases and review of the literature]: Sangre (Barc). 1993 Feb;38(1):51-5. Unique Identifier : AIDSLINE MED/93227134; Majluf-Cruz AS; Hurtado Monroy R; Souto-Meirino C; del Rio Chiriboga C; Simon J; Departamento de Hematologia, Instituto National de la Nutricion; Dr. Salvador Zubiran, Mexico, D.F.; Three cases of haemophagocytic syndrome (HPS) due to histoplasmosis in patients with the acquired immunodeficiency syndrome (AIDS) are described. At admission all had pancytopenia and the bone marrow aspirate showed typical haemophagocytosis and the presence of intracellular inclusions compatible with Histoplasma caps
Proposed resolutions for the 1993 TNA HOD. On uniform data reporting about needle sticks among health care workers in Texas.: Tex Nurs. 1993 Mar;67(3):5. Unique Identifier : AIDSLINE MED/93227163
AIDS Q & A. Antiretroviral drugs. Part 2.: Tex Nurs. 1993 Mar;67(3):8. Unique Identifier : AIDSLINE MED/93227164; Halloran J
[Follow-up and treatment of HIV-positive patients]: Tidsskr Nor Laegeforen. 1993 Mar 20;113(8):992. Unique Identifier : AIDSLINE MED/93227218; Bruun JN; Infeksjonsmedisinsk avdeling, Ulleval sykehus.
Involvement of CD8+ T cells in delayed-type hypersensitivity responses against bovine leukemia virus (BLV) induced in sheep vaccinated with recombinant vaccinia virus expressing BLV envelope glycoprotein.: Vet Pathol. 1993 Mar;30(2):104-10. Unique Identifier : AIDSLINE MED/93227515; Okada K; Ikeyama S; Ohishi K; Suzuki H; Sugimoto M; Numakunai S; Chiba T; Murakami K; Davis WC; Ohshima K; et al; Department of Veterinary Pathology, Faculty of Agriculture, Iwate; University, Japan.; Delayed-type hypersensitivity responses against bovine leukemia virus (BLV) envelope glycoprotein (gp60) were induced in the skin of sheep vaccinated with recombinant vaccinia virus (RVV) expressing BLV glycoprotein. The lesions were characterized by marked infiltration of lymphocytes, slight migration of neutrophils,
The neurotoxin-like sequence of human immunodeficiency virus gp120: a comparison of sequence data from patients with and without neurological symptoms.: Virus Genes. 1993 Feb;7(1):23-31. Unique Identifier : AIDSLINE MED/93227566; Sonnerborg A; Johansson B; Department of Virology, Central Microbiological Laboratory,; Stockholm, Sweden.; A region of the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp 120 has been claimed previously to be homologous to parts of snake venom neurotoxins and rabies virus glycoprotein (the neurotoxic loop). We have determined DNA sequences directly from a polymerase chain reaction amplified fragment co
HIV-1 seroprevalence among women attending sexually transmitted disease clinics in California. California Family of Surveys and Sentinel Surveillance Consortia [see comments]: West J Med. 1993 Jan;158(1):40-3. Unique Identifier : AIDSLINE MED/93227592; Wilson MJ; Marelich WD; Lemp GF; Ascher MS; Kerndt P; Kizer KW; California Department of Health Services, Sacramento 94234-7320.; To evaluate the distribution of the human immunodeficiency virus type 1 (HIV-1) epidemic among California women, we analyzed HIV-1 seroprevalence and risk factors among women attending sexually transmitted disease (STD) clinics in 21 local health jurisdictions. Using standardized protocols developed by the Centers for
Sentinel surveillance and prevention of HIV in women [editorial; comment]: West J Med. 1993 Jan;158(1):77-8. Unique Identifier : AIDSLINE MED/93227609; Lifson AR
Needle-stick injuries and blood contacts during invasive radiologic procedures: frequency and risk factors.: AJR Am J Roentgenol. 1993 May;160(5):1119-22. Unique Identifier : AIDSLINE MED/93227977; Hansen ME; Miller GL 3d; Redman HC; McIntire DD; Department of Radiology, University of Texas Southwestern Medical; Center, Dallas 75235-9071.; OBJECTIVE. Possible nosocomial transmission of blood-borne pathogens is a serious concern for health care workers and patients alike. Needle-stick injuries and blood contacts pose a risk of pathogen transmission during procedures. We performed a study to determine the frequency of injuries and blood contacts during in
AIDS-related non-Hodgkin's lymphoma: abdominal CT findings in 112 patients.: AJR Am J Roentgenol. 1993 May;160(5):1133-9. Unique Identifier : AIDSLINE MED/93227982; Radin DR; Esplin JA; Levine AM; Ralls PW; Department of Radiology, University of Southern California School; of Medicine, L.A. County-USC Medical Center 90033-1084.; OBJECTIVE. Non-Hodgkin s lymphoma is a common complication in patients with HIV infection. The purpose of this study was to analyze the abdominal CT findings in a large series of patients with this condition. MATERIALS AND METHODS. We retrospectively reviewed the abdominal CT examinations of 110 men and two women (21-
Visceral calcifications in patients with AIDS [letter; comment]: AJR Am J Roentgenol. 1993 May;160(5):1149-50. Unique Identifier : AIDSLINE MED/93227991; Towers MJ
MR imaging of the corpus callosum.: AJR Am J Roentgenol. 1993 May;160(5):949-55. Unique Identifier : AIDSLINE MED/93227998; Georgy BA; Hesselink JR; Jernigan TL; Department of Radiology, School of Medicine, University of; California, San Diego, La Jolla 92093.; The corpus callosum is the major axonal commissure of the brain, connecting the two cerebral hemispheres and providing communication between the cortical and subcortical neurons. With MR imaging in the sagittal plane, the corpus callosum can be depicted in great detail. We review the normal anatomy, development, and p
Pneumocystis carinii pneumonia in patients with ulcerative colitis treated with corticosteroids.: Am J Gastroenterol. 1993 Apr;88(4):574-7. Unique Identifier : AIDSLINE MED/93228034; Bernstein CN; Kolodny M; Block E; Shanahan F; Department of Medicine, University of California, Los Angeles.; Today, Pneumocystis carinii pneumonia (PCP) is typically associated with AIDS. However, in the pre-AIDS era, PCP was known to be associated with various immunodeficiency states, malignancies, and immunosuppressive therapy, particularly the use of corticosteroids. PCP has been reported to occur during immuno-suppressiv
Tracheoesophageal fistula complicating herpes esophagitis in AIDS.: Am J Gastroenterol. 1993 Apr;88(4):587-9. Unique Identifier : AIDSLINE MED/93228037; Cirillo NW; Lyon DT; Schuller AM; Department of Internal Medicine, Long Island College Hospital,; New York.; Immunocompromised individuals are susceptible to a variety of esophageal infections. Organisms responsible for esophagitis in patients with the acquired immunodeficiency syndrome (AIDS) are briefly reviewed. Usually confined to the esophageal mucosa, pathogens known to have the potential for transmural invasion are id
Intestinal perforation due to Mycobacterium tuberculosis in HIV-infected individuals: report of two cases.: Am J Gastroenterol. 1993 Apr;88(4):604-7. Unique Identifier : AIDSLINE MED/93228042; Friedenberg KA; Draguesku JO; Kiyabu M; Valenzuela JE; Department of Medicine, Los Angeles County-University of Southern; California Medical Center.; Intestinal perforation is an extremely uncommon complication of Mycobacterium tuberculosis (MTB) infection. We describe two cases of multiple intestinal perforations secondary to MTB in individuals infected with the human immunodeficiency virus (HIV) presenting at the Los Angeles County-University of Southern Californ
Clofazimine-induced eosinophilic gastroenteritis in AIDS [letter]: Am J Gastroenterol. 1993 Apr;88(4):612-3. Unique Identifier : AIDSLINE MED/93228047; Ravi S; Holubka J; Veneri R; Youn K; Khatib R
Mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) and its determinants: a cohort study in Kigali, Rwanda.: Am J Epidemiol. 1993 Mar 15;137(6):589-99. Unique Identifier : AIDSLINE MED/93228056; Lepage P; Van de Perre P; Msellati P; Hitimana DG; Simonon A; Van Goethem C; Mukamabano B; Karita E; Stevens AM; Mathieu G; et al; The authors report the results of the first 2 years of follow-up of a prospective cohort study on the mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) and its determinants which started in November 1988 in Kigali, Rwanda . The study sample consists of 218
Comparison of voluntary and blinded human immunodeficiency virus type 1 (HIV-1) seroprevalence surveys in a high prevalence sexually transmitted disease clinic population.: Am J Epidemiol. 1993 Mar 15;137(6):600-8. Unique Identifier : AIDSLINE MED/93228057; Schwarcz SK; Bolan GA; Kellogg TA; Kohn R; Lemp GF; San Francisco Department of Public Health, Division of Sexually; Transmitted Disease Control, CA 94102.; To compare the seroprevalence of and risk factors for human immunodeficiency virus infection (HIV) among patients attending a public sexually transmitted disease clinic, the authors conducted both voluntary and blinded seroprevalence surveys between June 1989 and August 1990. For the voluntary survey, every twenty-fif
Asserting a nurse's comparative fault, a manufacturer won a 30% reduction in a $l50,000 award [news]: Am J Nurs. 1993 Feb;93(2):9. Unique Identifier : AIDSLINE MED/93228106
Plasmodium falciparum-associated anemia in children at a large urban hospital in Zaire.: Am J Trop Med Hyg. 1993 Mar;48(3):365-71. Unique Identifier : AIDSLINE MED/93228177; Hedberg K; Shaffer N; Davachi F; Hightower A; Lyamba B; Paluku KM; Nguyen-Dinh P; Breman JG; Division of Parasitic Diseases, Centers for Disease Control,; Atlanta, Georgia.; Chloroquine-resistant Plasmodium falciparum malaria and human virus (HIV) infection through blood transfusions used to treat malaria-associated anemia are causes of increasing morbidity and mortality among children in Africa. To evaluate the role of malaria and other risk factors for pediatric anemia, we conducted a s
Detection of HIV-1 by polymerase chain reaction and culture in seronegative intravenous drug users in an inner-city emergency department.: Ann Emerg Med. 1993 May;22(5):769-75. Unique Identifier : AIDSLINE MED/93228247; Kelen GD; Chanmugam A; Meyer WA 3d; Farzadegan H; Stone D; Quinn TC; Division of Emergency Medicine, Johns Hopkins University School; of Medicine, Baltimore, MD.; STUDY BACKGROUND: After a health care worker s unprotected exposure to a patient s blood, the current recommendation is to obtain consent from the source for serologic testing for HIV. If the test is negative, no further follow-up of the exposed provider is usually indicated. OBJECTIVE: To determine if patients testin
AIDS and the common man.: Ann Intern Med. 1993 May 15;118(10):819. Unique Identifier : AIDSLINE MED/93228275; Burris JF; Georgetown University Medical Center, Washington, DC 20007.
The hazards of misguided compassion [editorial; comment] [see comments]: Ann Intern Med. 1993 May 15;118(10):822-3. Unique Identifier : AIDSLINE MED/93228277; Stolley PD
Cost-effective treatment of Candida esophagitis [letter; comment]: Ann Intern Med. 1993 May 15;118(10):824. Unique Identifier : AIDSLINE MED/93228278; Berman DS; Wenglin BD
Isolation and characterization of simian immunodeficiency virus from African white-crowned mangabey monkeys (Cercocebus torquatus lunulatus).: Arch Virol. 1993;129(1-4):77-92. Unique Identifier : AIDSLINE GENBANK/D01112; Tomonaga K; Katahira J; Fukasawa M; Hassan MA; Kawamura M; Akari H; Miura T; Goto T; Nakai M; Suleman M; et al; Research Center for Immunodeficiency Virus, Kyoto University,; Japan.; Forty-eight of 236 sera from seven species of African non-human primates in Kenya , including those of white-crowned mangabey monkeys (Cercocebus torquatus lunulatus) had antibodies to simian immunodeficiency viruses (SIVs). Isolates of simian lentivirus were obtained from seropositi
Relations between social skills and high-risk sexual interactions among adolescents. Current issues and future directions.: Behav Modif. 1993 Apr;17(2):113-35. Unique Identifier : AIDSLINE MED/93228565; Nangle DW; Hansen DJ; University of Mississippi Medical Center.; Researchers have begun to employ social-skills training in efforts to change the sexual behavior of adolescents. However, despite the promise of social-skills training, little is known about how social skills are related to the sexual practices of adolescents. The present article reviews the current literature and pro
[Sigmoid sinus thrombosis, a therapeutic problem]: Laryngorhinootologie. 1993 Mar;72(3):153-7. Unique Identifier : AIDSLINE MED/93228722; Furst G; Mann W; Univ.-HNO-Klinik Mainz.; Thrombosis of the sigmoid sinus is a relatively uncommon illness. It may present in a septic or bland form, and the latter is more or less asymptomatic. Angiography, computerised tomography and magnetic resonance imaging are all at our disposal for diagnosis of both types of thrombosis, and proper diagnosis of the spe
Mycobacterial infection in HIV+ patients detected with a new immunological method (TB test).: Allerg Immunol (Paris). 1993 Jan;25(1):24-5. Unique Identifier : AIDSLINE MED/93228774; Vanacore R; Paladini A; Ceretelli S; Savalli E; Sbrana S; Falsini R; Scasso A; Ambrogi F; Clinica Medica 1, Universita di Pisa.; Antibody response to antigen A60 (a mycobacterial antigen) was evaluated in ELISA in 18 HIV+ subjects with clinical and cultural evidences of mycobacterial infections, in 10 HIV+ subjects without Mycobacterial infections and in 22 healthy donors. We found higher levels of specific IgG in the HIV+ patients with Mycobac
[Information on AIDS in companies (news)]: Allerg Immunol (Paris). 1993 Jan;25(1):39. Unique Identifier : AIDSLINE MED/93228777
Biology of Toxoplasma gondii [editorial]: AIDS. 1993 Mar;7(3):299-316. Unique Identifier : AIDSLINE MED/93228876; Wong SY; Remington JS; In conclusion, a large body of new information on the biology and immunology of T. gondii has accumulated in the past several years. Much of this is due to the advent of AIDS and the increased funding made available to researchers interested in opportunistic infections in this patient population. These scientific advaa
HIV-1 infection and modulation of cytokine and growth factor expression in Kaposi's sarcoma-derived cells in vitro.: AIDS. 1993 Mar;7(3):317-22. Unique Identifier : AIDSLINE MED/93228877; Huang YQ; Li JJ; Kim KS; Nicolaides A; Zhang WG; Le J; Poiesz BJ; Friedman-Kien AE; Department of Microbiology, New York University Medical Center,; NY 10016.; OBJECTIVES: HIV-1 transcripts have been detected in AIDS-related Kaposi s sarcoma (KS) tissues within the factor XIIIa + dermal dendrocytes present in the tumor. Various cytokines and growth factors have been shown to influence the growth of KS-derived cells in vitro. HIV-1 preferentially infects CD4+ cells and has ala
Fibroblast-derived factors preserve viability in vitro of mononuclear cells isolated from subjects with HIV-1 infection.: AIDS. 1993 Mar;7(3):323-9. Unique Identifier : AIDSLINE MED/93228878; Pandolfi F; Oliva A; Sacco G; Polidori V; Liberatore D; Mezzaroma I; Giovannetti A; Kurnick JT; Aiuti F; Department of Allergy and Clinical Immunology, La Sapienza; University, Rome, Italy.; OBJECTIVE: Peripheral blood mononuclear cells (PBMC) from HIV-infected subjects have an increased mortality rate (MR) when incubated in vitro for 3 days in a culture medium. We have previously shown that fibroblast-conditioned medium (FCM) can preserve viability, without significant activation, of human lymphocytes ina
Effects of retroviral infections on immune function in African-American intravenous drug users.: AIDS. 1993 Mar;7(3):331-5. Unique Identifier : AIDSLINE MED/93228879; Klimas NG; Page JB; Patarca R; Chitwood D; Morgan R; Fletcher MA; Miami Veterans Administration Medical Center, Florida.; OBJECTIVES: To determine the effect of retrovirus infection and co-infection, and intravenous substance use, on immune function in African-Americans. DESIGN: A cohort of South Florida street-recruited African-American intravenous drug users formed the study population. The cohort consisted of 90 HIV-negative & huma
Highly specific V3 peptide enzyme immunoassay for serotyping HIV-1 specimens from Thailand.: AIDS. 1993 Mar;7(3):337-40. Unique Identifier : AIDSLINE MED/93228880; Pau CP; Lee-Thomas S; Auwanit W; George JR; Ou CY; Parekh BS; Granade TC; Holloman DL; Phillips S; Schochetman G; et al; Division of HIV/AIDS, Centers for Disease Control, Atlanta,; Georgia 30333.; OBJECTIVE: To develop and evaluate a simple V3 peptide-based enzyme immunoassay (EIA) for large-scale serotyping of HIV-1 specimens from Thailand . DESIGN: Serologic reactivities with synthetic peptides derived from the V3 loop of gp120 were used for typing HIV-1 specimens. METHOD
Evaluation of mechanical transmission of HIV by the African soft tick, Ornithodoros moubata.: AIDS. 1993 Mar;7(3):341-7. Unique Identifier : AIDSLINE MED/93228881; Humphery-Smith I; Donker G; Turzo A; Chastel C; Schmidt-Mayerova H; Departement de Microbiologie et Sante Publique, Faculte de; Medecine, Brest, France.; OBJECTIVES: To assess the ability of the African Hut Tampan, Ornithodoros moubata, to mechanically transmit HIV-1 and to re-appraise HIV-1 infectivity in an arthropod cell line at 28 and 35 degrees C. DESIGN: To evaluate HIV-1 transmission by O. moubata, as determined by HIV-1 survival, blood-meal size and interval
The natural history of cryptosporidial diarrhoea in HIV-infected patients.: AIDS. 1993 Mar;7(3):349-54. Unique Identifier : AIDSLINE MED/93228882; McGowan I; Hawkins AS; Weller IV; Academic Department of Genito-Urinary Medicine, University; College London Medical School, UK.; OBJECTIVE: To determine the natural history of cryptosporidial infection in HIV-infected individuals. DESIGN: Retrospective study. SETTING: University teaching hospital HIV inpatient and outpatient unit. PATIENTS: Thirty-eight HIV-infected patients presenting with cryptosporidial diarrhoea between April 1986 and July
Utility of dapsone for prophylaxis of Pneumocystis carinii pneumonia in trimethoprim-sulfamethoxazole-intolerant, HIV-infected individuals.: AIDS. 1993 Mar;7(3):355-9. Unique Identifier : AIDSLINE MED/93228883; Jorde UP; Horowitz HW; Wormser GP; Department of Medicine, New York Medical College, Valhalla 10595.; OBJECTIVE: To determine the safety and efficacy of 100 mg dapsone three times weekly for Pneumocystis carinii pneumonia (PCP) prophylaxis in HIV-infected, trimethoprim-sulfamethoxazole (TMP-SMX)-intolerant patients. DESIGN: Retrospective chart review of patients followed-up to 22 May 1992. SETTING: Infectious diseases
Elevated serum levels of neopterin but not beta 2-microglobulin in HIV-1-seronegative injecting drug users.: AIDS. 1993 Mar;7(3):361-7. Unique Identifier : AIDSLINE MED/93228884; Strickler HD; Blanchard JF; Vlahov D; Taylor E; Munoz A; Nelson KE; Margolick JB; Viral Epidemiology Branch, National Cancer Institute, National; Institutes of Health, Bethesda, MD 20892.; OBJECTIVE: To determine whether injecting drug use is associated with cellular immune activation in the absence of HIV-1 infection. DESIGN: Serum levels of neopterin and beta 2-microglobulin (beta 2M) were measured cross-sectionally in injecting drug users (IDU) enrolled in a prospective study. SUBJECTS AND METHODS: T
Hepatomegaly with severe steatosis in HIV-seropositive patients.: AIDS. 1993 Mar;7(3):379-85. Unique Identifier : AIDSLINE MED/93228887; Freiman JP; Helfert KE; Hamrell MR; Stein DS; Division of Epidemiology and Surveillance, Food and Drug; Administration, Rockville, Maryland.; OBJECTIVE: To describe death attributed to severe hepatomegaly and macrovesicular steatosis without inflammation or necrosis in HIV-seropositive patients without AIDS. PATIENTS: Patients from the AIDS Clinical Trials Group (ACTG) Adverse Reactions and the Food and Drug Administration s ( F
Blood transfusion practices in Mwanza Region, Tanzania. Bugando Medical Centre.: AIDS. 1993 Mar;7(3):387-92. Unique Identifier : AIDSLINE MED/93228888; Gumodoka B; Vos J; Kigadye FC; van Asten H; Dolmans WM; Borgdorff MW; Bugando Medical Centre, Mwanza, Tanzania.; OBJECTIVE: To determine what proportion of blood transfusions given in Mwanza Region, Tanzania could be avoided. METHODS: A total of 1029 patients who received a blood transfusion in one of eight hospitals were analysed. Two sets of criteria for avoidable blood transfusions were
European Community Concerted Action on HIV seroprevalence among sexually transmitted disease patients in 18 European sentinel networks. The European Study Group.: AIDS. 1993 Mar;7(3):393-400. Unique Identifier : AIDSLINE MED/93228889; OBJECTIVE: Monitoring HIV infection in sentinel populations of sexually transmitted disease (STD) patients in several geographical areas. This paper describes the main characteristics of the study populations and compares HIV seropositivity rates within and between networks in different subgroups: homo-/bisexuals, int
HIV infection in European female sex workers: epidemiological link with use of petroleum-based lubricants. European Working Group on HIV Infection in Female Prostitutes.: AIDS. 1993 Mar;7(3):401-8. Unique Identifier : AIDSLINE MED/93228890; OBJECTIVES: To assess the prevalence of and risk factors associated with HIV infection in European female sex workers, particularly sexual risk factors. DESIGN: Multicentre cross-sectional study performed in nine European countries. METHODS: Female sex workers voluntarily enrolled between September 1990 and November 1
HIV risk-related sexual behaviors among heterosexuals in New York City: associations with race, sex, and intravenous drug use.: AIDS. 1993 Mar;7(3):409-14. Unique Identifier : AIDSLINE MED/93228891; Kim MY; Marmor M; Dubin N; Wolfe H; Department of Environmental Medicine, New York University Medical; Center, NY 10010-2598.; OBJECTIVE: To investigate the relationship between heterosexual behaviors associated with HIV infection and ethnicity, sex, and intravenous drug use. METHODS: Subjects were recruited from Bellevue Hospital Center, New York City between 1986 and 1989, and interviewed about sexual behaviors and intravenous drug use. Ana
Improved survival from diagnosis of AIDS in adult cases in the United Kingdom and bias due to reporting delays.: AIDS. 1993 Mar;7(3):415-20. Unique Identifier : AIDSLINE MED/93228892; Whitmore-Overton SE; Tillett HE; Evans BG; Allardice GM; Public Health Laboratory Service Communicable Disease; Surveillance Centre, London, England.; OBJECTIVE: To measure developments in survival patterns among United Kingdom adult AIDS cases. DESIGN: A follow-up survey of cases reported voluntarily to the national surveillance schemes was undertaken to obtain up-to-date information on vital status. METHODS: All reporting clinician
The epidemiology of AIDS in the Vellore region, southern India.: AIDS. 1993 Mar;7(3):421-4. Unique Identifier : AIDSLINE MED/93228893; John TJ; Babu PG; Saraswathi NK; Jayakumari H; Selvaraj R; Kaur A; Chacko S; Jacob M; Ramachandran P; Tripathy SP; National AIDS Reference and Surveillance Centre, Christian; Medical College Hospital, Vellore, India.; OBJECTIVE: To describe the epidemiology of patients with AIDS in Vellore region, Southern India . DESIGN AND METHODS: Sixty-one patients with AIDS were diagnosed and treated between July 1987 and June 1992. Information on their demographic characteristics and probable modes of acquir
Disclosing HIV seropositivity to significant others.: AIDS. 1993 Mar;7(3):425-31. Unique Identifier : AIDSLINE MED/93228894; Hays RB; McKusick L; Pollack L; Hilliard R; Hoff C; Coates TJ; Center for AIDS Prevention Studies, University of California, San; Francisco 94105.; OBJECTIVES: To examine gay men s patterns of self-disclosure of HIV seropositivity to friends, lovers, relatives and colleagues; to assess the effects of disclosure; and to identify reasons for not disclosing to particular individuals. DESIGN: Longitudinal questionnaire survey of gay men. METHODS: A total of 163 HIV-p
p24 antigenaemia and clinical response to zidovudine therapy [letter]: AIDS. 1993 Mar;7(3):434-5. Unique Identifier : AIDSLINE MED/93228896; Montroni M; Silvestri G; Butini L; Regnery C; Bartocci C; Buffarini F; Danieli G
Case study of zidovudine overdose [letter]: AIDS. 1993 Mar;7(3):436-7. Unique Identifier : AIDSLINE MED/93228897; Valentine C; Williams O; Davis A; Hind CR; Saltissi S; Arya OP; Brown R
The presence or absence of gp120/gp160 bands on indeterminate western blots: predictive value for HIV seroconversion [letter]: AIDS. 1993 Mar;7(3):437-8. Unique Identifier : AIDSLINE MED/93228898; King R; Frey S; Beisha R; Van de Perre P; Karita E; Allen S
No antibodies to granulocyte macrophage colony-stimulating factor with prolonged use in AIDS [letter]: AIDS. 1993 Mar;7(3):438. Unique Identifier : AIDSLINE MED/93228899; Scadden DT; Agosti J
Letrazuril therapy for cryptosporidiosis: clinical response and pharmacokinetics [letter]: AIDS. 1993 Mar;7(3):438-40. Unique Identifier : AIDSLINE MED/93228900; Victor GH; Conway B; Hawley-Foss NC; Manion D; Sahai J
The relative efficacy of oral dapsone and nebulized pentamidine as prophylaxis for Pneumocystis carinii pneumonia [letter; comment]: AIDS. 1993 Mar;7(3):440. Unique Identifier : AIDSLINE MED/93228901; Sabin CA; Phillips AN
Prevalence of injecting drug use provides the context for epidemiology of HIV among injecting drug users [letter; comment]: AIDS. 1993 Mar;7(3):442-3. Unique Identifier : AIDSLINE MED/93228903; Frischer M; Green S; Goldberg D
Temporal trend of HIV infection among pregnant women in a reference hospital in Barcelona [letter]: AIDS. 1993 Mar;7(3):443-4. Unique Identifier : AIDSLINE MED/93228904; Coll O; Torne A; Ercilla G; Sanchez E
Sexual risk and perception of risk for HIV infection among multiethnic family-planning clients.: Am J Prev Med. 1993 Mar-Apr;9(2):92-5. Unique Identifier : AIDSLINE MED/93229045; Eversley RB; Newstetter A; Avins A; Beirnes D; Haynes-Sanstad K; Hearst N; Center for AIDS Prevention Studies, University of California, San; Francisco 94105.; Little is known about the relationship among having risks for human immunodeficiency virus (HIV) infection, perceiving oneself at risk, and initiating risk reduction for young sexually active women. We surveyed a multiethnic sample of 267 young-adult female family planning clients attending Planned Parenthood clinics
Glycosylation of the external domain of SIV gp41 is influenced by the cytoplasmic tail [letter]: AIDS Res Hum Retroviruses. 1993 Mar;9(3):197-8. Unique Identifier : AIDSLINE MED/93229105; Jowett JB; Jones IM
In vivo administration to rhesus monkeys of a CD4-specific monoclonal antibody capable of blocking AIDS virus replication.: AIDS Res Hum Retroviruses. 1993 Mar;9(3):199-207. Unique Identifier : AIDSLINE MED/93229106; Reimann KA; Burkly LC; Burrus B; Waite BC; Lord CI; Letvin NL; New England Regional Primate Research Center, Harvard Medical; School, Southborough, Massachusetts 01772.; Monoclonal antibodies (mAbs) specific for CD4 are potent inhibitors of HIV replication in vitro. These agents may be useful prophylactically or in chronic HIV infection if they can be administered without inducing immunosuppression. In the present study, we explored the safety of a CD4-specific murine mAb in rhesus mo
The reactivities of HIV-1+ human sera with solid-phase V3 loop peptides can be poor predictors of their reactivities with V3 loops on native gp120 molecules.: AIDS Res Hum Retroviruses. 1993 Mar;9(3):209-19. Unique Identifier : AIDSLINE MED/93229107; Moore JP; Aaron Diamond AIDS Research Center, New York University School of; Medicine, New York 10016.; The binding of HIV-1+ human serum antibodies to solid phase-adsorbed V3 loop peptides from the IIIB, SF-2, and MN isolates was compared with the abilities of the same peptides to inhibit binding of the sera to the homologous or heterologous native gp120 molecules. The reactivities of the sera with the solid-phase pept
Complement activation by gp160 glycoprotein of HIV-1.: AIDS Res Hum Retroviruses. 1993 Mar;9(3):229-33. Unique Identifier : AIDSLINE MED/93229109; Thieblemont N; Haeffner-Cavaillon N; Weiss L; Maillet F; Kazatchkine MD; Institute National de la Sante et de la Recherche Medicale U28,; Hopital Broussais, Paris, France.; The ability of the gp160 envelope glycoprotein of HIV-1 to activate human complement and to bind C3 fragments was investigated by incubating mammalian-derived recombinant gp160 with seronegative serum and by quantitating the binding of C3b/iC3b to the protein using a biotinylated monoclonal antibody directed against a
Induction of human immunodeficiency virus-specific T cell responses in rhesus monkeys by synthetic peptides from gp160.: AIDS Res Hum Retroviruses. 1993 Mar;9(3):235-40. Unique Identifier : AIDSLINE MED/93229110; Nehete PN; Satterfield WC; Matherne CM; Arlinghaus RB; Sastry KJ; Department of Molecular Pathology, University of Texas M.D.; Anderson Cancer Center, Houston 77030.; We have previously identified several synthetic peptides from conserved regions of the human immunodeficiency virus (HIV) envelope protein gp160 that have the capacity to induce broadly reactive T cell responses against gp160 in mice of several major histocompatibility complex (MHC) haplotypes. In the present investig
T cell response to staphylococcal superantigens by asymptomatic HIV-infected individuals exhibits selective changes in T cell receptor V beta-chain usage.: AIDS Res Hum Retroviruses. 1993 Mar;9(3):241-6. Unique Identifier : AIDSLINE MED/93229111; Bisset LR; Opravil M; Ludwig E; Fierz W; Department of Internal Medicine, University Hospital, Zurich,; Switzerland.; Recognition that the murine mammary tumor C-type retrovirus and the replication-defective murine leukemia virus have superantigen properties raises the specter that human immunodeficiency virus might also generate T cell impairment and destruction as a result of inherent superantigen properties. The observation that i
Human immunodeficiency virus type-1 antibody in 6703 institutionalized mentally retarded clients: an unlinked serosurvey at seven California developmental centers.: AIDS Res Hum Retroviruses. 1993 Mar;9(3):247-9. Unique Identifier : AIDSLINE MED/93229112; Lohiya GS; Infectious Disease Laboratory, State Developmental Research; Institute, Costa Mesa, California 92626.; All clients residing in seven California developmental centers were tested for human immunodeficiency virus type 1 (HIV) antibody in an unlinked serosurvey. Of 6703 clients, 11 (0.16%) were found positive for HIV-1 antibody by confirmatory Western blot and immunofluorescent antibody tests. Universal blood and body flu
Humoral aspects of anti-HIV immune responses in Zairians with AIDS: lower antigenemia does not correlate with immune complex levels.: AIDS Res Hum Retroviruses. 1993 Mar;9(3):251-8. Unique Identifier : AIDSLINE MED/93229113; Kashala O; Kayembe K; Kanki P; Mukeba P; Diese M; Kalengayi M; Izzia KW; Essex M; Department of Cancer Biology, Harvard School of Public Health,; Boston, Massachusetts 02115.; Serological patterns of anti-HIV immune responses of 150 HIV-infected (65 asymptomatic, 19 ARC, 66 AIDS) and 150 HIV-negative healthy Zairians were studied to determine the clinical significance of p24 antigen, and anti-p24 antibody, particularly in relation to p24 relative binding capacity (RBC) and circulating immun
Detection of HIV-1 distribution in different blood fractions by two nucleic acid amplification assays.: AIDS Res Hum Retroviruses. 1993 Mar;9(3):259-65. Unique Identifier : AIDSLINE MED/93229114; Bruisten S; van Gemen B; Koppelman M; Rasch M; van Strijp D; Schukkink R; Beyer R; Weigel H; Lens P; Huisman H; Central Laboratory of The Netherlands Red Cross Blood Transfusion; Service, Amsterdam.; A new amplification procedure, NASBA (nucleic acid sequence-based amplification), was used together with the polymerase chain reaction (PCR) to detect HIV-1 sequences in different blood fractions of both HIV-infected and uninfected samples. We tested whole blood, plasma, peripheral blood mononuclear cells (PBMCs), and
Cutaneous disorders and viral gene expression in HIV-1 transgenic mice.: AIDS Res Hum Retroviruses. 1993 Mar;9(3):267-75. Unique Identifier : AIDSLINE MED/93229115; Kopp JB; Rooney JF; Wohlenberg C; Dorfman N; Marinos NJ; Bryant JL; Katz SI; Notkins AL; Klotman PE; Laboratory of Developmental Biology, National Institute of Dental; Research, National Institutes of Health, Bethesda, Maryland; 20892.; Patients infected with HIV-1 experience several hyperproliferative skin disorders, including seborrheic dermatitis, ichthyosis, and psoriasis. Transgenic mice carrying a subgenomic HIV-1 proviral construct lacking the gag and pol genes were found to develop proliferative epidermal lesions, manifested as diffuse epider
Early pathogenesis of disease caused by SIVsmmPBj14 molecular clone 1.9 in macaques.: AIDS Res Hum Retroviruses. 1993 Mar;9(3):277-86. Unique Identifier : AIDSLINE MED/93229116; Israel ZR; Dean GA; Maul DH; O'Neil SP; Dreitz MJ; Mullins JI; Fultz PN; Hoover EA; Department of Pathology, Colorado State University, Fort Collins; 80523.; We have studied the early pathogenesis of infection by molecular clone 1.9 of SIVsmmPBj14 in pig-tailed and cynomolgus macaques. Like the uncloned PBj14 parent, SIVsmmPBj14-1.9 consistently induced an acute clinical syndrome characterized by behavioral depression, fever, profuse diarrhea, dehydration, lymphadenopathy,
New concepts in AIDS pathogenesis.: AIDS Res Hum Retroviruses. 1993 Mar;9(3):287-9. Unique Identifier : AIDSLINE MED/93229117; Gougeon ML; Colizzi V; Dalgleish A; Montagnier L; Unite D'Oncologie Virale, Institut Pasteur, Paris, France.; The concept that HIV causes AIDS only by directly killing CD4 cells has been questioned by a number of investigators. There has been experimental support for a number of indirect mechanisms such as apoptosis, anergy, superantigen-induced cell proliferation and depletion, defective signaling, molecular mimicry, and aut
Frequency of adult T-cell leukaemia/lymphoma and HTLV-I in Ibadan, Nigeria.: Br J Cancer. 1993 Apr;67(4):783-6. Unique Identifier : AIDSLINE MED/93229261; Williams CK; Alexander SS; Bodner A; Levine A; Saxinger C; Gallo RC; Blattner WA; Department of Haematology, College of Medicine University of; Ibadan, Nigeria.; Sera from a small sample of adult blood donors, healthy school children and patients with lymphoma, leukaemia, non-haematologic cancer, congenital and inflammatory disorders from Ibadan, Nigeria were screened for HTLV-I antibody by an enzyme-linked immunoabsorbent assay and confir
Unsafe sex and HIV-1 transmission [news]: Nurs Stand. 1993 Feb 24-Mar 2;7(23):16. Unique Identifier : AIDSLINE MED/93229296
Pneumonia link to HIV status in drug use [news]: Nurs Stand. 1993 Feb 24-Mar 2;7(23):17. Unique Identifier : AIDSLINE MED/93229297
Reassurance on risk of HIV-positive midwife [news]: Nurs Stand. 1993 Feb 24-Mar 2;7(23):5. Unique Identifier : AIDSLINE MED/93229310
Prejudice threatens effective HIV nursing [news]: Nurs Stand. 1993 Mar 10-16;7(25):10. Unique Identifier : AIDSLINE MED/93229315
Call to extend vigilance in tuberculosis [news]: Nurs Stand. 1993 Mar 10-16;7(25):17. Unique Identifier : AIDSLINE MED/93229316
AIDS focus. AIDS and women on the islands of Zanzibar.: Nurs Stand. 1993 Mar 10-16;7(25):48-50. Unique Identifier : AIDSLINE MED/93229328; Ali A
AIDS focus. The rehabilitation of people with AIDS.: Nurs Stand. 1993 Mar 10-16;7(25):51-3. Unique Identifier : AIDSLINE MED/93229329; Wells R
Analysis of lymphocyte subsets in patients with aplastic anemia before and during immunosuppressive therapy.: Ann Hematol. 1993 Mar;66(3):127-9. Unique Identifier : AIDSLINE MED/93229568; Mentzel U; Vogt H; Rossol R; Geissler RG; Maurer A; Ganser A; Trommer WE; Hoelzer D; Department of Hematology, Clinic of Goethe University, Frankfurt,; Germany.; To define the contribution of T-lymphocyte subsets in the development of aplastic anemia (AA), T-cell subpopulations including alpha beta T cells, gamma delta T cells, and delta TCS1-positive gamma delta T cells, were analyzed by cytophotometry in the peripheral blood (PB) and bone marrow (BM) of patients with AA befo
Generation and characterization of ex vivo propagated autologous CD8+ cells used for adoptive immunotherapy of patients infected with human immunodeficiency virus.: Blood. 1993 Apr 15;81(8):2085-92. Unique Identifier : AIDSLINE MED/93229748; Whiteside TL; Elder EM; Moody D; Armstrong J; Ho M; Rinaldo C; Huang X; Torpey D; Gupta P; McMahon D; et al; Department of Pathology, University of Pittsburgh School of; Medicine, PA.; Cytolytic T lymphocytes play an important role in host defense against viral infections, including human immunodeficiency virus (HIV). In a phase I clinical trial (protocol 080 of the AIDS Clinical Trials Group), generation of CD8+ effector cells from peripheral blood of patients with acquired immunodeficiency syndrom
A phase 1 study of adoptive transfer of autologous CD8+ T lymphocytes in patients with acquired immunodeficiency syndrome (AIDS)-related complex or AIDS.: Blood. 1993 Apr 15;81(8):2093-101. Unique Identifier : AIDSLINE MED/93229749; Ho M; Armstrong J; McMahon D; Pazin G; Huang XL; Rinaldo C; Whiteside T; Tripoli C; Levine G; Moody D; et al; Department of Infectious Diseases and Microbiology, Graduate; School of Public Health, PA 15261.; Based on preclinical studies showing that CD8+ T lymphocytes of human immunodeficiency syndrome (HIV)-infected subjects have anti-HIV activities, a phase 1 study was undertaken to determine the safety and feasibility of infusing in vitro purified, activated, and expanded CD8+ cells as a therapeutic measure in seven pa
Effect of neuropeptide Y on natural killer activity of normal human lymphocytes.: Brain Behav Immun. 1993 Mar;7(1):70-8. Unique Identifier : AIDSLINE MED/93229815; Nair MP; Schwartz SA; Wu K; Kronfol Z; Department of Pediatrics, University of Michigan, Ann Arbor.; The in vitro effect of neuropeptide Y (NPY) on natural killer (NK) cell activities of normal lymphocytes was investigated. NPY at 10(-9) to 10(-12) M concentrations produced significant suppression of NK activity against K 562 target cells. NPY at 10(-9) to 10(-12) M concentrations also produced significant inhibitory
A novel variety of atypical Pneumocystis carinii infection after long-term prophylactic pentamidine inhalation in an AIDS patient: large lower lobe pneumocystoma.: Clin Investig. 1993 Apr;71(4):310-3. Unique Identifier : AIDSLINE MED/93229863; Albrecht H; Stellbrink HJ; Fenske S; Koch J; Greten H; Medizinische Kernklinik und Poliklinik, Universitatskrankenhaus; Eppendorf, Hamburg.; Atypical pulmonary manifestations of Pneumocystis carinii infection and fair numbers of extrapulmonary and disseminated infections have lately been documented in patients with human immunodeficiency virus infection treated prophylactically with inhalative pentamidine. We report the case of a 32-year-old homosexual pat
Chronic pentamidine aerosol prophylaxis does not induce QT prolongation.: Clin Investig. 1993 Apr;71(4):319-22. Unique Identifier : AIDSLINE MED/93229865; Thalhammer C; Bogner JR; Lohmoller G; Medizinische Poliklinik, Universitat Munchen.; Intravenous administration of pentamidine is known to cause long-QT syndrome (Torsade de pointes tachycardias and large QT prolongation) in rare cases and to cause small QT prolongation regularly. A similar pattern is seen with other drugs known to cause a long-QT syndrome. Pentamidine aerosol prophylaxis is commonly
[Good future perspectives and optimistic attitude. AIDS congress in Amsterdam]: Gynakol Geburtshilfliche Rundsch. 1993;33(1):41-3. Unique Identifier : AIDSLINE MED/93229941; Hutterer J; Osterreichisches AIDS-Komitee, Wien, Osterreich.
Mainstream America hears it is safe from AIDS [news]: BMJ. 1993 Mar 13;306(6879):674-5. Unique Identifier : AIDSLINE MED/93229992; Tanne JH
The community-based database prototype of the southeast Florida AIDS Information Network.: Bull Med Libr Assoc. 1993 Apr;81(2):223-6. Unique Identifier : AIDSLINE MED/93230109; Burrows S; Louis Calder Memorial Library, University of Miami School of; Medicine, FL 33101.
AIDS literature underestimated [letter] [see comments]: Bull Med Libr Assoc. 1993 Apr;81(2):234. Unique Identifier : AIDSLINE MED/93230112; FitzSimons DW
Effects of aerosolized pentamidine in AIDS patients.: Monaldi Arch Chest Dis. 1993;48(1):100. Unique Identifier : AIDSLINE MED/93230243; Nardini S; Divisione di Pneumologia, Ospedale Civile--USL, Venezia-Mestre,; Italy.
Splenectomy in human immunodeficiency virus-related thrombocytopenia.: Br J Surg. 1993 Mar;80(3):330-3. Unique Identifier : AIDSLINE MED/93230392; Alonso M; Gossot D; Bourstyn E; Galera MJ; Oksenhendler E; Celerier M; Clot P; Department of Surgery 1, Hopital Saint Louis, Paris, France.; To evaluate the efficacy and safety of splenectomy in patients with human immunodeficiency virus (HIV)-related thrombocytopenia, 30 HIV-infected patients with thrombocytopenia (platelet count
HIV vulnerability and the adult survivor of childhood sexual abuse.: Child Abuse Negl. 1993 Mar-Apr;17(2):291-8. Unique Identifier : AIDSLINE MED/93230434; Allers CT; Benjack KJ; White J; Rousey JT; Department of Counseling and Psychological Services, Georgia; State University, Atlanta 30303.; The purpose of this article is to sensitize clinicians working in the field of childhood physical/sexual abuse to the connection between untreated childhood traumatization and HIV high-risk behaviors. The characteristic abuse symptoms of chronic depression, sexual compulsivity, revictimization, and substance abuse are
Handpiece sterilization--the debate continues.: J Can Dent Assoc. 1993 Apr;59(4):355-62. Unique Identifier : AIDSLINE MED/93230469; Hardie J; Department of Dentistry, Vancouver General Hospital.
Bloodborne pathogens in the health care setting: risk for transmission. Laboratory Centre for Disease Control, Health and Welfare Canada.: J Can Dent Assoc. 1993 Apr;59(4):363-70. Unique Identifier : AIDSLINE MED/93230470
Physical and chemical methods for enhancing rapid detection of viruses and other agents.: Clin Microbiol Rev. 1993 Apr;6(2):150-75. Unique Identifier : AIDSLINE MED/93230516; Hughes JH; Department of Medical Microbiology & Immunology, Ohio State; University, Columbus 43210.; Viral replication events can be enhanced by physical, chemical, or heat treatment of cells. The centrifugation of cells can stimulate them to proliferate, reduce their generation times, and activate gene expression. Human endothelial cells can be activated to release cyclo-oxygenase metabolites after rocking for 5 min
Therapeutic applications of anti-CD4 antibodies.: Crit Rev Ther Drug Carrier Syst. 1993;10(1):29-63. Unique Identifier : AIDSLINE MED/93230596; Olive D; Mawas C; Institut Paoli-Calmettes, INSERM U. 119, Marseille, France.; The CD4 molecule represents a major functional T-cell surface molecule, defining an important T-cell subset, which also is expressed on monocyte, dendritic, and Langerhans cells. Various in vivo studies have demonstrated its implication in various steps of physiological T-cell activation: 1. CD4 interacts with its phy
The prevalence of paranasal sinus disease in HIV infection and AIDS on cranial MR imaging.: Clin Radiol. 1993 Mar;47(3):166-9. Unique Identifier : AIDSLINE MED/93230815; Chong WK; Hall-Craggs MA; Wilkinson ID; Paley M; Grant A; Miller R; Harrison MJ; MRI Unit, Middlesex Hospital, London.; Sinusitis poses a difficult clinical challenge in the management of patients with AIDS because of high rates of relapse and the association with unusual pathogens. To determine the prevalence and severity of sinus disease in this group we prospectively analysed the condition of the paranasal sinuses shown on cranial M
Proteolytic modification of beta 2-microglobulin in human serum.: Dan Med Bull. 1993 Mar;40(1):56-64. Unique Identifier : AIDSLINE MED/93230960; Nissen MH; Department of Medical Oncology, Finseninstitutet, Rigshospitalet,; Copenhagen.
Evaluation of a dual-color flow cytometry immunophenotyping panel in a multicenter quality assurance program.: Cytometry. 1993;14(3):307-17. Unique Identifier : AIDSLINE MED/93231014; Schenker EL; Hultin LE; Bauer KD; Ferbas J; Margolick JB; Giorgi JV; Department of Medicine, UCLA School of Medicine 90024.; A basic immunophenotyping panel that employed dual-color combinations of fluorescein isothiocyanate (FITC) and phycoerythrin (PE) conjugated monoclonal antibodies (mAb; FITC-CD45/PE-CD14, FITC-IgG1/PE-IgG2, FITC-CD3/PE-CD8, FITC-CD3/PE-CD4, FITC-CD3/PE-CD16 + PE-CD56, and PE-CD19) was utilized in a quality assurance p
Seroprevalence of HIV-1 and HIV-2 infection among children diagnosed with protein-calorie malnutrition in Nigeria.: Epidemiol Infect. 1993 Apr;110(2):373-8. Unique Identifier : AIDSLINE MED/93231252; Fischer GD; Rinaldo CR Jr; Gbadero D; Kingsley LA; Ndimbie O; Howard C; Montemayor PC; Langer A; Sibolboro W; Department of Pathology, Graduate School of Public Health,; University of Pittsburgh School of Medicine, PA 15261.; Excessive weight loss due to protein calorie malnutrition (PCM) is a significant problem in Nigerian children. This syndrome may be difficult to differentiate from the wasting disease caused by human immunodeficiency virus type 1 (HIV-1) infection. We studied 70 children admitted to the Baptist Medical Center in Ogbom
Antenatal survey for the seroprevalence of HTLV-1 infections in the West Midlands, England.: Epidemiol Infect. 1993 Apr;110(2):379-87. Unique Identifier : AIDSLINE MED/93231253; Nightingale S; Orton D; Ratcliffe D; Skidmore S; Tosswill J; Desselberger U; Midland Centre for Neurosurgery and Neurology, Smethwick, West; Midlands.; The sera of 3522 women who attended an antenatal clinic in Birmingham, England were tested anonymously for antibodies against HTLV-1. Samples from 5 women (0.14%) were positive, one serum showed indeterminate reactivity. Two of the women (0.06%) were born in the West Indies (of Afro-Caribbean ethnic origin), one (0.03
Treatment and serological studies of an Italian case of penicilliosis marneffei contracted in Thailand by a drug addict infected with the human immunodeficiency virus.: Eur J Epidemiol. 1993 Jan;9(1):79-85. Unique Identifier : AIDSLINE MED/93231286; Viviani MA; Tortorano AM; Rizzardini G; Quirino T; Kaufman L; Padhye AA; Ajello L; Istituto di Igiene e Medicina Preventiva, Universita degli Studi; di Milano, Italy.; A case of disseminated penicilliosis marneffei, the first to be diagnosed in Italy , is described in a male HIV-positive drug addict. The patient had visited Thailand several times in the two years prior to his hospitalization. The presenting si
Interferon-gamma-activated monocytes impair infectivity of HIV particles by an oxygen metabolite-dependent reaction.: Immunology. 1993 Feb;78(2):171-6. Unique Identifier : AIDSLINE MED/93231621; Ennen J; Kurth R; Paul-Ehrlich Institute, Department of Biotechnology, Langen,; Germany.; Mononuclear phagocytes generate microbicidal oxygen metabolites spontaneously and after phagocytic stimulation by a NADPH-dependent enzymatic reaction called the oxidative burst. The spontaneous release of reactive oxygen radicals and intermediates (ROI) increases five- to eightfold after treatment of monocytes with t
The use of primary care services by drug users attending a HIV prevention unit.: Ir Med J. 1993 Mar;86(2):53-5. Unique Identifier : AIDSLINE MED/93231793; Bury G; O'Kelly F; Pomeroy L; General Practice Professorial Unit, UCD, Dublin.; Intravenous drug using clients of a Dublin HIV Prevention Unit were interviewed about their use of general practitioner services. Sixty eight percent of clients had visited a GP within the previous year and 48% were registered with a GP under the General Medical Services (GMS) Scheme. Of 161 interviewees 60 were being
Phosphorylation of HIV-1 gag proteins by protein kinase C.: J Biol Chem. 1993 Apr 25;268(12):8698-703. Unique Identifier : AIDSLINE MED/93232024; Burnette B; Yu G; Felsted RL; Laboratory of Biological Chemistry, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.; We have demonstrated that the 17-kDa N-terminal matrix protein (p17gag) of HIV-1 Pr55gag is a substrate for protein kinase C (PKC). Phosphorylation of p17gag and Pr55gag was studied in vivo by infecting COS-7 cells with a recombinant vaccinia virus containing the HIV-1 gag-pol gene. Basal gag protein phosphorylation w
Colorimetric detection for PCR amplified HIV-1 DNA using magnetic beads.: J Virol Methods. 1993 Mar;41(3):341-50. Unique Identifier : AIDSLINE MED/93232123; Suzuki K; Okamoto N; Kano T; Biomedical Research Center, Olympus Corporation, East Setauket,; NY 11733.; A rapid and nonradioactive detection method for polymerase chain reaction (PCR) amplified HIV-1 DNA was developed using a colorimetric detection system. Hybridization between biotin-labeled amplified targets and digoxigenin-capture probes occurs in solution followed by efficient and rapid capture onto streptavidin-mag
Culturally tailored HIV-AIDS risk-reduction messages targeted to African-American urban women: impact on risk sensitization and risk reduction.: J Consult Clin Psychol. 1993 Apr;61(2):291-5. Unique Identifier : AIDSLINE MED/93232383; Kalichman SC; Kelly JA; Hunter TL; Murphy DA; Tyler R; Department of Psychiatry and Mental Health Sciences, Medical; College of Wisconsin, Milwaukee 53226.; African-American women recruited from low-income housing projects in Chicago (N = 106) were randomly assigned to view 1 of 3 20-min videotapes: a standard public health service tape on prevention of acquired immunodeficiency syndrome (AIDS), the same public health service tape but matching presenter and participant et
Final year dental students' views on cross-infection precautions.: J Dent. 1993 Apr;21(2):105-10. Unique Identifier : AIDSLINE MED/93232391; Nuttall NM; Gilbert AD; Department of Dental Health, University of Dundee, Scotland, UK.; This study was undertaken to determine the influence that undergraduate training currently has on the formation of clinical management strategies for minimizing cross-infection, among final year dental students. A 10-page questionnaire was sent to final year dental students attending 15 of the UK s 16 dental schools.
Assessing dental patients for their risk of being carriers of a blood-borne virus: the views of final year dental students [published erratum appears in J Dent 1993 Aug;21(4):215]: J Dent. 1993 Apr;21(2):99-104. Unique Identifier : AIDSLINE MED/93232400; Nuttall NM; Gilbert AD; Department of Dental Health, University of Dundee, Scotland, UK.; A questionnaire was sent to final year dental students in all but one of the dental schools in the UK in 1991. The response was 447 out of 739 (60.5%). The students were asked about how they intended to approach various aspects of patient care once they were qualified and in practice. Almost half (44%) said they would
Increased secretion of tumor necrosis factor-alpha, interleukin-1-beta, and interleukin-6 by alveolar macrophages from patients with sarcoidosis.: J Allergy Clin Immunol. 1993 Apr;91(4):939-49. Unique Identifier : AIDSLINE MED/93232485; Steffen M; Petersen J; Oldigs M; Karmeier A; Magnussen H; Thiele HG; Raedler A; Department of Internal Medicine, University Hospital Eppendorf,; Hamburg, Germany.; BACKGROUND: Alveolar macrophages from patients with sarcoidosis were analyzed for their ability to secrete tumor necrosis factor-alpha (TNF-alpha), interleukin-1-beta (IL-1-beta), and interleukin-6 (IL-6). RESULTS: Constitutive release of all three monokines in these patients was concomitantly increased in the active
Fluconazole resistance in Candida in patients with AIDS--a therapeutic approach [see comments]: J Infect. 1993 Mar;26(2):117-25. Unique Identifier : AIDSLINE MED/93232626; Ng TT; Denning DW; Regional Department of Infectious Diseases and Tropical Medicine,; Monsall Hospital, Manchester, U.K.
Application of the polymerase chain reaction to the diagnosis of human toxoplasmosis.: J Infect. 1993 Mar;26(2):147-58. Unique Identifier : AIDSLINE MED/93232629; Johnson JD; Butcher PD; Savva D; Holliman RE; Toxoplasma Reference Laboratory, St. George's Hospital Medical; School, London, U.K.; Toxoplasmosis may cause significant damage to the developing fetus and is a life-threatening opportunistic infection in immunocompromised persons. Serological investigation is unreliable, while isolation of the parasite is time consuming and may lack sensitivity. We have developed a system for detecting Toxoplasma gon
Cardiac dysfunction in paediatric HIV infection.: J Infect. 1993 Mar;26(2):191-4. Unique Identifier : AIDSLINE MED/93232635; Croft NM; Jacob AJ; Godman MJ; Boon NA; Mok JY; Regional Infectious Diseases Unit, City Hospital, Edinburgh, U.K.; A child under long term surveillance for vertically acquired HIV-I infection developed respiratory symptoms. Dilated cardiomyopathy was diagnosed. Clinical and echocardiographic assessment of six other children with symptomatic HIV disease showed no evidence of cardiac dysfunction. The exact prevalence of this complic
Serum albumin and other parameters in HIV infected intravenous drug users [letter]: J Infect. 1993 Mar;26(2):229-32. Unique Identifier : AIDSLINE MED/93232649; Cirasino L; Landonio G; Imbriani M; Ragaini S
GenStar: a method for de novo drug design.: J Comput Aided Mol Des. 1993 Feb;7(1):23-43. Unique Identifier : AIDSLINE MED/93232881; Rotstein SH; Murcko MA; Vertex Pharmaceuticals Incorporated, Cambridge, MA 02139.; A novel method, which we call GenStar, has been developed to suggest chemically reasonable structures which fill the active sites of enzymes. The proposed molecules provide good steric contact with the enzyme and exist in low-energy conformations. These structures are composed entirely of sp3 carbons which are grown s
Morphine-induced alterations in thymocyte subpopulations of B6C3F1 mice.: J Pharmacol Exp Ther. 1993 Apr;265(1):81-8. Unique Identifier : AIDSLINE MED/93233044; Freier DO; Fuchs BA; Department of Pharmacology and Toxicology, Medical College of; Virginia, Virginia Commonwealth University, Richmond.; Morphine has been reported to possess immunosuppressive actions in both in vitro as well as in vivo assays of immune function. Our work in female B6C3F1 mice, surgically implanted with a 75-mg time release morphine pellet, has confirmed previous reports of a rapid loss in the cellularity of the spleen and thymus. To e
Performance of scored palpation, a point count, and dolorimetry in assessing unsuspected nonarticular tenderness.: J Rheumatol. 1993 Feb;20(2):352-7. Unique Identifier : AIDSLINE MED/93233090; Smythe HA; Buskila D; Gladman D; University of Toronto Rheumatic Disease Unit, ON, Canada.; Nonarticular tenderness was measured in 152 patients, 51 with rheumatoid arthritis, 50 with psoriatic arthritis, and 51 with human immunodeficiency virus infection. Three methods for assessing tenderness were used: a 14-site point count, scored tenderness at 10 sites (6 fibrositic and 4 control), and dolorimetry at th
Immunoglobulin-A detection and the investigation of clinical toxoplasmosis.: J Med Microbiol. 1993 Apr;38(4):286-92. Unique Identifier : AIDSLINE MED/93233159; Patel B; Young Y; Duffy K; Tanner RP; Johnson J; Holliman RE; Department of Medical Microbiology, St. George's Hospital,; London.; Current serological methods for the investigation of Toxoplasma gondii infection are unreliable for the diagnosis of congenital disease, reactivated infection associated with the acquired immune deficiency syndrome (AIDS), or the determination of the date of onset of infection. An enzyme-linked immunosorbent assay (EL
Listeria-associated pericarditis in an AIDS patient.: J Natl Med Assoc. 1993 Mar;85(3):225-8. Unique Identifier : AIDSLINE MED/93233183; Ferguson R; Yee S; Finkle H; Rose T; Schneider V; Gee G; Department of Medicine, Highland General Hospital, Oakland,; California 94602-1098.; Listeria monocytogenes is a pathogenic, facultative intracellular gram-positive rod, generally seen in cell-mediated immunocompromised states. In acquired immunodeficiency syndrome (AIDS), it most commonly presents as bacteremia or meningitis. An association with pericarditis has not been described previously in this
Multiple viral determinants contribute to pathogenicity of the acutely lethal simian immunodeficiency virus SIVsmmPBj variant.: J Virol. 1993 May;67(5):2466-74. Unique Identifier : AIDSLINE GENBANK/L09211; Novembre FJ; Johnson PR; Lewis MG; Anderson DC; Klumpp S; McClure HM; Hirsch VM; Laboratory of Infectious Diseases, National Institute of Allergy; and Infectious Diseases, Rockville, Maryland 20852.; Simian immunodeficiency virus (SIV) induces an immunodeficiency syndrome similar to human AIDS. Although the disease course of SIV-induced immunodeficiency is generally measured in months to years, a disease syndrome that results in death in 5 to 14 days has been described in pig-tailed macaques infected with the SIVs
Dominant negative mutants of human T-cell leukemia virus type I Rex and human immunodeficiency virus type 1 Rev fail to multimerize in vivo.: J Virol. 1993 May;67(5):2496-502. Unique Identifier : AIDSLINE MED/93233212; Bogerd H; Greene WC; Department of Medicine, Howard Hughes Medical Institute, Duke; University Medical Center, Durham, North Carolina 27710.; Human T-cell leukemia virus type I (HTLV-I) Rex and human immunodeficiency virus type 1 (HIV-1) Rev are essential gene products required for the replication of these two pathogenic human retroviruses. Both Rex and Rev act at a posttranscriptional level by binding to highly structured RNA-response elements, the Rex-res
Basic amino acids flanking the zinc finger of Moloney murine leukemia virus nucleocapsid protein NCp10 are critical for virus infectivity.: J Virol. 1993 May;67(5):2537-45. Unique Identifier : AIDSLINE MED/93233217; Housset V; De Rocquigny H; Roques BP; Darlix JL; LaboRetro Institut National de la Sante et de la Recherche; Medicale, Ecole Normale Superieure de Lyon, France.; Nucleocapsid (NC) protein NCp10 of Moloney murine leukemia virus is encoded by the 3 domain of gag and contains a zinc finger surrounded by basic amino acids. During virion assembly, NC protein is necessary for core formation and the NC zinc finger is required for the packaging of the genomic RNA dimer. In vitro NCp1
Human immunodeficiency virus type 1 envelope gp120 is cleaved after incubation with recombinant soluble CD4.: J Virol. 1993 May;67(5):2566-74. Unique Identifier : AIDSLINE MED/93233221; Werner A; Levy JA; Department of Medicine, School of Medicine, University of; California, San Francisco 94143-0128.; Human immunodeficiency virus type 1 (HIV-1) infects human CD4+ cells by a high-affinity interaction between its envelope glycoprotein gp120 and the CD4 molecule on the cell surface. Subsequent virus entry into the cells involves other steps, one of which could be cleavage of the gp120 followed by virus-cell fusion. Th
A Friend virus mutant that overcomes Fv-2rr host resistance encodes a small glycoprotein that dimerizes, is processed to cell surfaces, and specifically activates erythropoietin receptors.: J Virol. 1993 May;67(5):2611-20. Unique Identifier : AIDSLINE MED/93233226; Kozak SL; Hoatlin ME; Ferro FE Jr; Majumdar MK; Geib RW; Fox MT; Kabat D; Department of Biochemistry and Molecular Biology, School of; Medicine, Oregon Health Sciences University, Portland 97201-3098.; The env gene of Friend spleen focus-forming virus (SFFV) encodes a membrane glycoprotein (gp55) that is inefficiently (3 to 5%) processed from the rough endoplasmic reticulum to form a larger dimeric plasma membrane derivative (gp55p). Moreover, the SFFV env glycoprotein associates with erythropoietin receptors (EpoR)
Simian immunodeficiency virus RNA is efficiently encapsidated by human immunodeficiency virus type 1 particles.: J Virol. 1993 May;67(5):2681-8. Unique Identifier : AIDSLINE MED/93233234; Rizvi TA; Panganiban AT; McArdle Laboratory for Cancer Research, University of; Wisconsin--Madison 53706.; Packaging of retroviral RNA is attained through the specific recognition of a cis-acting encapsidation site (located near the 5 end of the viral RNA) by components of the Gag precursor protein. Human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) are two lentiviruses that lack apparent
Complement-mediated binding of naturally glycosylated and glycosylation-modified human immunodeficiency virus type 1 to human CR2 (CD21).: J Virol. 1993 May;67(5):2699-706. Unique Identifier : AIDSLINE MED/93233236; Montefiori DC; Stewart K; Ahearn JM; Zhou J; Zhou J; Department of Pathology, Vanderbilt University Medical School,; Nashville, Tennessee 37232-2515.; Particulate glycoproteins lacking sialic acid, such as desialylated enveloped viruses, readily activate complement through the alternative pathway. Human immunodeficiency virus type 1 (HIV-1) contains two heavily glycosylated and partially sialylated envelope glycoproteins: a surface gp120 and a transmembrane gp41. Th
Effects of amino acid changes in the extracellular domain of the human immunodeficiency virus type 1 gp41 envelope glycoprotein.: J Virol. 1993 May;67(5):2747-55. Unique Identifier : AIDSLINE MED/93233242; Cao J; Bergeron L; Helseth E; Thali M; Repke H; Sodroski J; Division of Human Retrovirology, Dana-Farber Cancer Institute,; Boston, Massachusetts.; Changes were introduced into conserved amino acids within the ectodomain of the human immunodeficiency virus type 1 (HIV-1) gp41 transmembrane envelope glycoprotein. The effect of these changes on the structure and function of the HIV-1 envelope glycoproteins was examined. The gp41 glycoprotein contains an amino-termi
Elimination of L-A double-stranded RNA virus of Saccharomyces cerevisiae by expression of gag and gag-pol from an L-A cDNA clone.: J Virol. 1993 May;67(5):2764-71. Unique Identifier : AIDSLINE MED/93233244; Valle RP; Wickner RB; Section on Genetics of Simple Eukaryotes, National Institute of; Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland; 20892.; We report that expression of a nearly full-length cDNA clone of the L-A double-stranded RNA virus causes virus loss in a wild-type strain of Saccharomyces cerevisiae. We show that in this system exclusion of the L-A virus is independent of the presence of the packaging site or of cis sites for replication and transcri
Assembly-defective point mutants of the human immunodeficiency virus type 1 Gag precursor phenotypically expressed in recombinant baculovirus-infected cells.: J Virol. 1993 May;67(5):2787-98. Unique Identifier : AIDSLINE MED/93233247; Hong SS; Boulanger P; Laboratoire de Virologie & Pathogenese Moleculaires, CNRS, URA; 1487, Institut de Biologie, Faculte de Medecine, Montpellier,; France.; Two substitution mutants of the human immunodeficiency virus type 1 gag gene product were isolated after nitrous acid mutagenesis of a recombinant baculovirus expressing a non-N-myristylated, p6-deleted Gag precursor (Pr49). Both mutants failed to assemble intracellular Gag virus-like particles, as does the parental r
Truncation of the cytoplasmic domain of the simian immunodeficiency virus envelope glycoprotein increases env incorporation into particles and fusogenicity and infectivity.: J Virol. 1993 May;67(5):2824-31. Unique Identifier : AIDSLINE MED/93233251; Zingler K; Littman DR; Department of Microbiology and Immunology, University of; California, San Francisco 94143-0414.; Growth of macaque simian immunodeficiency virus (SIVmac) in certain cloned human T-cell lines, such as HUT.78, selects for isolates containing a premature stop codon within the cytoplasmic domain of the transmembrane envelope glycoprotein. In contrast, propagation of virus in macaques or in their cultured T cells favo
The RRE of human immunodeficiency virus type 1 contributes to cell-type-specific viral tropism.: J Virol. 1993 May;67(5):2871-8. Unique Identifier : AIDSLINE MED/93233256; Dayton ET; Konings DA; Lim SY; Hsu RK; Butini L; Pantaleo G; Dayton AI; National Institute of Allergy and Infectious Diseases, Bethesda,; Maryland 20892.; As part of a general program investigating the mechanism of the Rev axis of human immunodeficiency virus type 1 (HIV-1) autoregulation, a series of proviral HIV-1 mutants which differ from the parental HXB2 strain at selected positions within the RRE were constructed. All of the mutations were designed to perturb the
Sequences downstream of the RNA initiation site regulate human T-cell lymphotropic virus type I basal gene expression.: J Virol. 1993 May;67(5):2894-902. Unique Identifier : AIDSLINE MED/93233259; Kashanchi F; Duvall JF; Lindholm PF; Radonovich MF; Brady JN; Laboratory of Molecular Virology, National Cancer Institute,; Bethesda, Maryland 20892.; Sequences which control basal human T-cell lymphotropic virus type I (HTLV-I) transcription probably play an important role in initiation and maintenance of virus replication. We have identified and analyzed a 45-nucleotide sequence (downstream regulatory element 1 [DRE 1]) at the boundary of the R/U5 region of the lo
The NF-kappa B binding site is necessary for efficient replication of simian immunodeficiency virus of macaques in primary macrophages but not in T cells in vitro.: J Virol. 1993 May;67(5):2908-13. Unique Identifier : AIDSLINE MED/93233261; Bellas RE; Hopkins N; Li Y; Center for Cancer Research, Massachusetts Institute of; Technology, Cambridge 02139.; We demonstrate here that the nuclear factor-kappa B (NF-kappa B) binding site in the simian immunodeficiency virus (SIVmac) long terminal repeat is essential for efficient virus replication in primary alveolar macrophages but dispensable for efficient replication in primary T cells. Mutation of the NF-kappa B site doe
Dilute passage promotes expression of genetic and phenotypic variants of human immunodeficiency virus type 1 in cell culture.: J Virol. 1993 May;67(5):2938-43. Unique Identifier : AIDSLINE MED/93233267; Sanchez-Palomino S; Rojas JM; Martinez MA; Fenyo EM; Najera R; Domingo E; Lopez-Galindez C; Centro de Biologia Celular y Retrovirus, Instituto de Salud; Carlos III, Majadahonda, Madrid, Spain.; We have studied the extent of genetic and phenotypic diversification of human immunodeficiency virus type 1 (HIV-1) upon 15 serial passages of clonal viral populations in MT-4 cell cultures. Several genetic and phenotypic modifications previously noted during evolution of HIV-1 in infected humans were also observed up
For AIDS treatment, vaccines, now think genes [news]: JAMA. 1993 May 5;269(17):2189, 2193. Unique Identifier : AIDSLINE MED/93233273; Goldsmith MF
The nation's changing blood supply system.: JAMA. 1993 May 5;269(17):2239-45. Unique Identifier : AIDSLINE MED/93233293; McCullough J; Department of Laboratory Medicine and Pathology, University of; Minnesota Hospital and Clinic, Minneapolis 55455.
Blood transfusion--a potential source of HIV/AIDS spread [editorial]: JPMA J Pak Med Assoc. 1993 Jan;43(1):1. Unique Identifier : AIDSLINE MED/93233311; Mujeeb SA
Prevalence and pattern of HIV infection in Karachi.: JPMA J Pak Med Assoc. 1993 Jan;43(1):2-4. Unique Identifier : AIDSLINE MED/93233315; Mujeeb SA; Hafeez A; Blood Transfusion Services, Jinnah Postgraduate Medical Centre,; Karachi.; Two thousand seven hundred and seventy six subjects comprising 844 high risk and 1932 low risk group were screened for HIV antibodies by ELISA and western blot. Eight subjects from high risk group were HIV positive. They included three prisoners, two sexually promiscuous, two seafarers and one recipient of blood. The
Does HIV piggyback on CD4-like surface proteins of sperm, viruses, and bacteria? Implications for co-transmission, cellular tropism and the induction of autoimmunity in AIDS.: J Theor Biol. 1993 Jan 21;160(2):249-64. Unique Identifier : AIDSLINE MED/93233372; Root-Bernstein RS; Hobbs SH; Department of Physiology, Michigan State University, East Lansing; 48824.; Coinfections of human immunodeficiency virus (HIV), EBV, and HTLV or sperm proteins act synergistically to enhance infectivity and replication and expand cellular tropism. While some aspects of these synergisms are understood, others are not. We have found that membrane or surface proteins of
Generation and analysis of vaccinia virus recombinants.: Methods Enzymol. 1993;217:557-81. Unique Identifier : AIDSLINE MED/93233493; Mazzara GP; Destree A; Mahr A; Therion Biologics Corporation, Cambridge, Massachusetts 02142.
It is HIV: immediate and long-term plans.: Med J Aust. 1993 Mar 1;158(5):323-6. Unique Identifier : AIDSLINE MED/93233523; Quin JW; Benson EM; Department of Clinical Immunology and Allergy, Westmead Hospital,; NSW.
The rational use of the HIV antibody test.: Med J Aust. 1993 Mar 1;158(5):327-8. Unique Identifier : AIDSLINE MED/93233524; Dwyer JM; Stewart GJ; McDonald P; AIDS Treatment and Research Centre, Prince Henry Hospital, Little; Bay, NSW.; The clinical skills of the medical profession can be used to identify unsuspected HIV infection in a cost-effective way. However, other strategies are needed to optimise the detection of HIV infection and achieve the benefits to patients and the community that result from detection.
Liability for failure to diagnose HIV infection and AIDS [see comments]: Med J Aust. 1993 Mar 1;158(5):329-30. Unique Identifier : AIDSLINE MED/93233525; Hirsch D; Cashman and Partners, Sydney South, NSW.; In the United States a patient has sued a doctor for failing to diagnose AIDS, resulting in a two-year delay before correct diagnosis and treatment. At least one similar case has been commenced in Australia and more are likely. The time has come
Research problems in general practice [letter]: Med J Aust. 1993 Mar 1;158(5):360-1. Unique Identifier : AIDSLINE MED/93233541; McMurchie M; Beveridge A; Bradford D; Genn W; Todhunter L
The drug-exposed mother and infant: a regional center experience.: Neonatal Netw. 1993 Apr;12(3):41-9. Unique Identifier : AIDSLINE MED/93233589; Zaichkin J; Houston RF; Drug-exposed mothers and infants continue to challenge maternal and infant health care resources. The woman who abuses drugs may have a complex social history and high resistance to change. Drug use may be intergenerational and long-standing. Although cocaine may be a drug of choice, there is often polydrug abuse, com
Recommendations of the Advisory Committee on Immunization Practices (ACIP): use of vaccines and immune globulins for persons with altered immunocompetence.: MMWR Morb Mortal Wkly Rep. 1993 Apr 9;42(RR-4):1-18. Unique Identifier : AIDSLINE MED/93233599
Impact of the expanded AIDS surveillance case definition on AIDS case reporting--United States, first quarter, 1993.: MMWR Morb Mortal Wkly Rep. 1993 Apr 30;42(16):308-10. Unique Identifier : AIDSLINE MED/93233602; On January 1, 1993, the acquired immunodeficiency syndrome (AIDS) surveillance case definition for adolescents and adults was expanded beyond the surveillance definition published in 1987 (1) to include all human immunodeficiency virus (HIV)-infected persons with severe immunosuppression (
Tissue-specific expression of human CD4 in transgenic mice.: Mol Cell Biol. 1993 May;13(5):2952-8. Unique Identifier : AIDSLINE MED/93233656; Gillespie FP; Doros L; Vitale J; Blackwell C; Gosselin J; Snyder BW; Wadsworth SC; TSI Corporation, Worcester, Massachusetts 01605.; The gene for the human CD4 glycoprotein, which serves as the receptor for human immunodeficiency virus type 1, along with approximately 23 kb of sequence upstream of the translational start site, was cloned. The ability of 5 flanking sequences to direct tissue-specific expression was tested in cell culture and in tra
The orphan receptor Rev-ErbA alpha activates transcription via a novel response element.: Mol Cell Biol. 1993 May;13(5):3113-21. Unique Identifier : AIDSLINE MED/93233672; Harding HP; Lazar MA; Department of Medicine, University of Pennsylvania School of; Medicine, Philadelphia 19104.; Rev-ErbA alpha (Rev-Erb) is a nuclear hormone receptor-related protein encoded on the opposite strand of the alpha-thyroid hormone receptor (TR) gene. This unusual genomic arrangement may have a regulatory role, but the conservation of human and rodent Rev-Erb amino acid sequences suggests that the protein itself has
[Treatment of secondary infections in symptomatic HIV-infections in childhood]: Monatsschr Kinderheilkd. 1993 Mar;141(3):178-200. Unique Identifier : AIDSLINE MED/93233673; Wahn V; Belohradsky BH; Enenkel-Stoodt S; Grosch-Worner I; Hoger P; Langhof M; Muller R; Notheis G; Schultheiss C; Schuster V; et al; Universitats-Kinderkliniken Dusseldorf.; Treatment of secondary infections in HIV infected children represents a problem of increasing importance in several children s hospitals. As it is unlikely that the AIDS-problem will be solved by itself within the next years it seems reasonable to summarize our current knowledge about opportunistic infections in order
[Intermediate results of a multicenter study in long-term management of HIV exposed and infected children]: Monatsschr Kinderheilkd. 1993 Mar;141(3):227-36. Unique Identifier : AIDSLINE MED/93233680; Grosch-Worner I; Belohradsky BH; Debatin KM; Enenkel-Stoodt S; Hoger P; Landwehr-Dobberstein C; Wahn V; Wintergerst U; Universitats-Kinderkliniken, Berlin.; AIM OF THE STUDY: In most cases (about 80%) the HIV-infection of children is acquired during pregnancy or birth. Therefore peculiarities for diagnostic procedures and in the natural course of the disease can be expected if compared to AIDS acquired at adult age. Further interesting questions are the frequency of the (
Childhood immunizations [letter; comment]: N Engl J Med. 1993 May 13;328(19):1420-1; discussion 1421-2. Unique Identifier : AIDSLINE MED/93233739; Kim-Farley RJ; Merson MH; Tulloch JL
[Should the testing policy for the prevention of HIV infections in patients and in health care personnel be changed?]: Ned Tijdschr Geneeskd. 1993 Apr 3;137(14):694-6. Unique Identifier : AIDSLINE MED/93233774; van Furth R; Academisch Ziekenhuis, afd. Infectieziekten, Leiden.
[AIDS and HIV infection as occupational disease (see comments)]: Ned Tijdschr Geneeskd. 1993 Apr 3;137(14):696-701. Unique Identifier : AIDSLINE MED/93233775; Houweling H; Rijksinstituut voor Volksgezondheid en Milieuhygiene, Centrum; voor Epidemiologie, Bilthoven.
[Iatrogenic HIV infection (published errata appear in Ned Tijdschr Geneeskd 1993 May 8;137(19):984 and 1993 Dec 25;137(52):2744)]: Ned Tijdschr Geneeskd. 1993 Apr 3;137(14):701-6. Unique Identifier : AIDSLINE MED/93233776; Houweling H; Rijksinstituut voor Volksgezondheid en Milieuhygiene, Centrum; voor Infectiziekten Epidemiologie, Bilthoven.
Early central nervous system changes in human immunodeficiency virus (HIV)-infection.: Neuropathol Appl Neurobiol. 1993 Feb;19(1):3-9. Unique Identifier : AIDSLINE MED/93233889; Gray F; Hurtrel M; Hurtrel B; Laboratoire d'Anatomie Pathologique et de Medecine Legale; (Neuropathologie), Faculte de Medecine Paris Ouest, Hopital; Raymond Poincare, Garches, France.; Early HIV infection of the CNS, as demonstrated by cerebrospinal fluid studies, seems relatively common. However most HIV carriers remain neurologically unimpaired during the incubation period. A few psychometric, radiological, and electrophysiological studies suggest that neurological abnormalities are present at ear
Hospital associated costs of treating patients with AIDS [see comments]: N Z Med J. 1993 Mar 10;106(951):76-8. Unique Identifier : AIDSLINE MED/93234029; Carlson R; Dickson N; McDermott J; Thomas M; Ellis-Pegler RB; Department of Preventive and Social Medicine, University of Otago; Medical School, Dunedin.; AIM. To determine the hospital associated costs of caring for patients with AIDS. METHOD. We reviewed the notes of all 40 patients with AIDS admitted to the Auckland Hospital infectious disease unit during 1988. We used the resource utilisation system (RUS) to determine costs. RESULTS. Costs were maximal in the month
Sexually transmitted diseases and HIV testing [letter; comment]: N Z Med J. 1993 Mar 10;106(951):88. Unique Identifier : AIDSLINE MED/93234035; Reid M
Outcome of adults with acquired immunodeficiency syndrome in Auckland 1983-9.: N Z Med J. 1993 Mar 24;106(952):93-6. Unique Identifier : AIDSLINE MED/93234050; Dickson NP; Sharples K; Carlson RV; McDermott J; Ellis-Pegler RB; Thomas MG; Department of Preventive and Social Medicine, University of Otago; Medical School, Dunedin.; AIMS. To assess the survival of Auckland residents diagnosed with AIDS between 1983 and 1989. METHODS. Retrospective case review RESULTS. Sixty nine Auckland residents were diagnosed with AIDS between 1983 and the end of 1989, and were cared for by the infectious disease unit, Auckland Hospital. The overall median sur
AIDS 1992 [news]: N Z Med J. 1993 Apr 14;106(953):146. Unique Identifier : AIDSLINE MED/93234068
Twins and HIV [letter; comment]: Pediatrics. 1993 May;91(5):1019-20. Unique Identifier : AIDSLINE MED/93234157; Glomb WB; Davidson SL; Lee SS; Durfee MJ
HIV and smooth muscle tumors [letter; comment]: Pediatrics. 1993 May;91(5):1020-1. Unique Identifier : AIDSLINE MED/93234158; Murphy SB; Chadwick EG
Study reveals isolation and strain in HIV/AIDS workers [news]: Nurs Times. 1993 Mar 10-16;89(10):10. Unique Identifier : AIDSLINE MED/93234248; McMillan S
A private matter [news] [see comments]: Nurs Times. 1993 Mar 10-16;89(10):22. Unique Identifier : AIDSLINE MED/93234251; Hodges C
Confidentiality paramount in occupational health department [letter; comment]: Nurs Times. 1993 Mar 31-Apr 6;89(13):12. Unique Identifier : AIDSLINE MED/93234265; Gorton S
Evidence for interstrand quadruplex formation in the dimerization of human immunodeficiency virus 1 genomic RNA [see comments]: Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3393-7. Unique Identifier : AIDSLINE MED/93234503; Sundquist WI; Heaphy S; Department of Biochemistry, University of Utah, Salt Lake City; 84132.; Retroviruses package two homologous single-stranded RNA genomes within a gag protein-RNA complex. In mature virion particles, the two RNA strands are thought to associate primarily through direct RNA-RNA interactions, although the structural basis for this stable association is unknown. We now report that a 127-nucleo
Inhibition of gene expression by triple helix-directed DNA cross-linking at specific sites.: Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3501-5. Unique Identifier : AIDSLINE MED/93234525; Grigoriev M; Praseuth D; Guieysse AL; Robin P; Thuong NT; Helene C; Harel-Bellan A; Laboratoire de Biologie des Tumeurs Humaines, Centre National de; la Recherche Scientifique, Villejuif, France.; Synthetic oligodeoxynucleotides represent promising tools for gene inhibition in live systems. Triple helix-forming oligonucleotides, which bind to double-stranded DNA, are of special interest since they are targeted to the gene itself rather than to its mRNA product, as in the antisense strategy. Triple helix-forming
The unusual UVA-dependent antiviral properties of the furoisocoumarin, coriandrin.: Photochem Photobiol. 1993 Mar;57(3):491-6. Unique Identifier : AIDSLINE MED/93234645; Hudson JB; Graham EA; Harris L; Ashwood-Smith MJ; Division of Medical Microbiology, University of British Columbia,; Vancouver, Canada.; The novel furoisocoumarin, coriandrin, which was found recently to possess an interesting combination of photobiological properties, was investigated for antiviral activity in the presence and absence of UVA (long-wavelength ultraviolet radiation). In contrast to results obtained with other antiviral furocoumarins, su
[Detection of RNA packaging signal of HIV-1 and its application for a novel AIDS therapy]: Tanpakushitsu Kakusan Koso. 1993 Mar;38(4):779-83. Unique Identifier : AIDSLINE MED/93234810; Hayashi T; Iwakura Y; Department of Viral Infection, University of Tokyo, Japan.
Drug companies join forces in search for AIDS therapy [news] [published erratum appears in Science 1993 May 14;260(5110):879]: Science. 1993 Apr 23;260(5107):482. Unique Identifier : AIDSLINE MED/93235047; Cohen J
[Substitute drug treatments with methadone]: Ther Umsch. 1993 Mar;50(3):139-47. Unique Identifier : AIDSLINE MED/93235150; von Bardeleben U; Stohler R; Petitjean S; Ladewig D; Psychiatrische Universitatsklinik, Basel.; Methadone maintenance treatment for patients with opiate addiction, started in the Canton of Basel in 1980, today includes more than 600 patients, with a marked increase since 1987 due to a change in inclusion criteria following the spreading of HIV infections. Data from 500 patients, gathered in 1991/92 on sociodemog
[Future prospects in treatment of drug dependent patients]: Ther Umsch. 1993 Mar;50(3):199-203. Unique Identifier : AIDSLINE MED/93235158; Ladewig D; Psychiatrische Universitatsklinik, Basel.; During the last 25 years, an important evolution in therapeutic-rehabilitative strategies for drug addicts was observed. Many inputs came from social pedagogics. Great demands are again put on the medical profession in relation to AIDS and substitution programs. In the future the engagement of the medical profession w
Sexual networking in provincial Thailand.: Stud Fam Plann. 1993 Jan-Feb;24(1):1-17. Unique Identifier : AIDSLINE MED/93235244; Havanon N; Bennett A; Knodel J; Graduate School, Srinakharinwirot University, Bangkok, Thailand.; Thailand is currently experiencing a major HIV epidemic, spread primarily through heterosexual contact. Patronage of prostitutes is relatively common. In-depth, open-ended interviews were conducted in a Central Thai province with a purposive sample of 181 urban men who had had se
[Syphilis meets AIDS. Syphilis seen in relation to the AIDS epidemic--a review]: Ugeskr Laeger. 1993 Mar 29;155(13):947-51. Unique Identifier : AIDSLINE MED/93235325; Weismann K; Sondergaard J; Dermato-venerologisk afdeling A., Bispebjerg Hospital, Kobenhavn.; The incidence of syphilis in Denmark has changed within the last ten years. From being a relatively common disease at the end of the 1970 s and beginning of the 1980 s, the incidence has fallen considerably. It is assumed that the c
[WR in patients with secondary syphilis and HIV infection]: Ugeskr Laeger. 1993 Mar 29;155(13):955-7. Unique Identifier : AIDSLINE MED/93235327; Weismann K; Petersen LJ; Petersen CS; Dermato-venerologisk afdeling A., Bispebjerg Hospital, Kobenhavn.; In recent years, there have been sporadic reports of aberrant manifestations of syphilis and a changed syphilis serology in AIDS patients, which might indicate difficulties in diagnosing the infection and monitoring the response to penicillin treatment. Six male patients aged 25 to 42 years with asymptomatic HIV infec
Making sense [editorial]: W V Med J. 1993 Mar;89(3):113. Unique Identifier : AIDSLINE MED/93235438; Wheeling SD
The stereotactic biopsy diagnosis of focal intracerebral lesions in AIDS patients.: Acta Neurol Scand. 1993 Mar;87(3):228-33. Unique Identifier : AIDSLINE MED/93235540; Feiden W; Bise K; Steude U; Pfister HW; Moller AA; Department of Neurosurgery, University of Munich, Germany.; Focal intracerebral lesions were biopsied stereotactically in 23 adult HIV-infected patients, the main indication for which was the failure to respond to anti-toxoplasma treatment. A cerebral disease was the initial or main complaint in 19 of them. In 22 of 25 stereotactic approaches, a clear-cut morphological diagnos
Mepron for AIDS-related pneumonia [news]: Am Pharm. 1993 Mar;NS33(3):14-5. Unique Identifier : AIDSLINE MED/93235761
PMA survey cites advances in AIDS research [news]: Am Pharm. 1993 Apr;NS33(4):8-9. Unique Identifier : AIDSLINE MED/93235778
The lymphadenopathy of HIV infection.: Am J Clin Pathol. 1993 Apr;99(4):397-401. Unique Identifier : AIDSLINE MED/93235830; Baroni CD; Uccini S; Department of Human Biopathology, University La Sapienza, Rome,; Italy.
Risk of human immunodeficiency virus infection among emergency department workers.: Am J Med. 1993 Apr;94(4):363-70. Unique Identifier : AIDSLINE MED/93235859; Marcus R; Culver DH; Bell DM; Srivastava PU; Mendelson MH; Zalenski RJ; Farber B; Fligner D; Hassett J; Quinn TC; et al; HIV Infections Branch, Centers for Disease Control and; Prevention, Atlanta, Georgia 30333.; PURPOSE: To estimate (1) the prevalence of human immunodeficiency virus (HIV) infection in emergency department (ED) patients, (2) the frequency of blood contact (BC) in ED workers (EDWs), (3) the efficacy of gloves in preventing BC, and (4) the risk of HIV infection in EDWs due to BC. PATIENTS AND METHODS: We conduct
Strongyloides hyperinfection in patients coinfected with HTLV-I and S. stercoralis [letter; comment]: Am J Med. 1993 Apr;94(4):447-9. Unique Identifier : AIDSLINE MED/93235875; Phelps KR
Pneumothorax in AIDS patients: operative management.: Am Surg. 1993 Mar;59(3):200-4. Unique Identifier : AIDSLINE MED/93236235; Horowitz MD; Oliva H; Division of Thoracic and Cardiovascular Surgery, University of; Miami/Jackson Memorial Medical Center, Florida.; Acquired immunodeficiency syndrome (AIDS) is a devastating disease. Pneumocystis carinii pneumonia (PCP) is a major clinical manifestation of AIDS. A 2-year experience with eight operations for PCP-associated pneumothorax in seven AIDS patients was reviewed. Initial treatment was tube thoracostomy in all cases. Operat
Angiolymphoid hyperplasia with eosinophilia (histiocytoid hemangioma): evaluation of treatment options.: Ann Otol Rhinol Laryngol. 1993 Apr;102(4 Pt 1):303-8. Unique Identifier : AIDSLINE MED/93236246; Cheney ML; Googe P; Bhatt S; Hibberd PL; Department of Otolaryngology, Massachusetts Eye and Ear; Infirmary, Boston.; Angiolymphoid hyperplasia with eosinophilia is an uncommon benign vascular proliferative lesion of unknown cause. In this report, a case is presented of a patient who was confirmed to be positive for human immunodeficiency virus and in whom the lesion had shown rapid accelerated growth. The case is used to illustrate
Epidemiology and oral manifestations of HIV infection.: Ann R Coll Surg Engl. 1993 Mar;75(2):111-4. Unique Identifier : AIDSLINE MED/93236253; Pindborg JJ; Department of Oral Pathology and Medicine, School of Dentistry,; Faculty of Health Sciences, University of Copenhagen, Denmark.
Patterns of sexuality in a high-risk sample: results from a survey of new intakes at a county jail.: Arch Sex Behav. 1993 Apr;22(2):111-29. Unique Identifier : AIDSLINE MED/93236459; Temple MT; Alcohol Research Group, Berkeley, California 94709.; Described the sexual habits and behaviors in a sample of individuals thought to be at high risk for infection with the AIDS virus. The sample is drawn from new arrestees at a county jail in the San Francisco Bay Area. Results indicate that the individuals in this sample are very sexually active: The majority began the
A factor analysis of the Klein sexual orientation grid in two disparate samples.: Arch Sex Behav. 1993 Apr;22(2):157-68. Unique Identifier : AIDSLINE MED/93236462; Weinrich JD; Snyder PJ; Pillard RC; Grant I; Jacobson DL; Robinson SR; McCutchan JA; HIV Neurobehavioral Research Center, University of California,; San Diego 92103.; Many researchers interested in sexual orientation can be separated into two camps: The lumpers, who try to reduce sexual classifications to as small a number of categories as possible, and the splitters, who try to show differences among groups and individuals that make classification schemes increasingly difficult an
OSHA's new standard: exposure to bloodborne pathogens [published erratum appears in AAOHN J 1993 Apr;41(4):following 193] [see comments]: AAOHN J. 1993 Mar;41(3):136-42. Unique Identifier : AIDSLINE MED/93236606; Roup BJ; Most health care workers in the U.S. are covered by OSHA s new standard on bloodborne pathogens exposure. Individual states that have their own occupational agency must enact a Standard that is at least as strict. Key elements of the Standard include an exposure control plan, universal precautions, engineering control
The influence of perceived risk of exposure to human immunodeficiency virus on medical students' planned specialty choices.: Am J Emerg Med. 1993 Mar;11(2):143-8. Unique Identifier : AIDSLINE MED/93236618; Loring KE; Crandall CS; Kelen GD; School of Medicine, Johns Hopkins University, Baltimore, MD.; The purpose of this report is to determine the influence of the acquired immunodeficiency syndrome (AIDS) epidemic on medical students training and career plans through a prospective, anonymous self-administered survey of 10 Likert-scaled (1 strongly agree to 5 strongly disagree) responses to statements assessing att
Viral inactivation and reduction in cellular blood products.: Rev Fr Transfus Hemobiol. 1993 Jan;36(1):83-91. Unique Identifier : AIDSLINE MED/93236667; Friedman LI; Stromberg RR; American Red Cross, Holland Laboratory, Rockville, MD.; Even though the risks associated with the transfusion of blood products are lower than ever before, considerable efforts are being employed to improve the safety of the blood supply. Based upon available data, a six log (99.9999%) reduction in virus level from screened and tested blood components should significantly
[Industrial pasteurization of plasma and criteria of quality]: Rev Fr Transfus Hemobiol. 1993 Jan;36(1):93-102. Unique Identifier : AIDSLINE MED/93236668; Burnouf-Radosevich M; Burnouf T; Huart JJ; Centre Regional de Transfusion Sanguine, Lille.; The approach followed in the design of a large-scale pasteurization treatment (60 degrees C for 10 hours in the liquid state) of fresh frozen plasma is presented. Various aspects thought to influence the viral safety of such a product are discussed. They are based largely upon the fact that, although it is subjected t
A comparison of human immunodeficiency virus (HIV) seropositivity and hepatitis B surface antigenemia (HBs Ag) among the same group of apparently healthy pregnant women in Lagos, Nigeria: a preliminary report.: Viral Immunol. 1993 Spring;6(1):43-7. Unique Identifier : AIDSLINE MED/93236717; Obi CL; Anyiwo CE; Nnatu SN; Agbonlahor DE; Esumeh FI; Karpas A; Department of Biological Sciences, University of Lagos, Nigeria.; Two hundred and fifty apparently healthy pregnant women attending the Obstetrics and Gynecology Clinic of the Lagos University Teaching Hospital (LUTH), Lagos, Nigeria were screened for a comparison of the prevalence of HIV seropositivity and hepatitis B surface antigenemia (HBs A
Changes in the cytotoxic T-cell repertoire of HIV-1-infected individuals: relationship to disease progression.: Viral Immunol. 1993 Spring;6(1):85-95. Unique Identifier : AIDSLINE MED/93236722; Grant MD; Smaill FM; Laurie K; Rosenthal KL; Department of Pathology, McMaster University Health Sciences; Centre, Hamilton, Ontario, Canada.; The repertoire of antigen-specific receptors expressed on T lymphocytes is shaped by fixed genetic and variable environmental selective pressures. Recent technological advances have enabled the analysis of T-cell receptor (TCR) expression in the context of selective pressures arising through normal immune system devel
[WIP (Workgroup Infection Prevention), or: campaign against hospital infection. Infection control: knowing is one, doing is two (interview by Toine de Graaf)]: TVZ. 1993 Jan 21;(2):64-6. Unique Identifier : AIDSLINE MED/93236736; van den Broek PJ
Rehabilitation medicine consultation in persons hospitalized with AIDS. An analysis of thirty cases.: Am J Phys Med Rehabil. 1993 Apr;72(2):90-6. Unique Identifier : AIDSLINE MED/93236794; O'Dell MW; Department of Physical Medicine, Graduate Hospital, Philadelphia,; Pennsylvania.; This retrospective study outlines interventions taken as a result of rehabilitation medicine consultation in persons hospitalized with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS). The medical records of 30 persons with HIV infection consecutively referred for rehabilitati
Gene therapy of the immune system.: Annu Rev Immunol. 1993;11:297-329. Unique Identifier : AIDSLINE MED/93236822; Cournoyer D; Caskey CT; Department of Medicine, McGill University, Montreal, Quebec,; Canada.; Many applications of somatic gene therapy relate to the immune system. Several forms of inherited immunodeficiencies are candidates for treatment by gene transfer. Adenosine deaminase (ADA) deficiency causes a form of severe combined immunodeficiency. Stable gene transfer and expression of human ADA has now been obtai
Human immunodeficiency virus nephropathy.: Pediatr Nephrol. 1993 Apr;7(2):220-5. Unique Identifier : AIDSLINE MED/93237040; Strauss J; Zilleruelo G; Abitbol C; Montane B; Pardo V; Department of Pediatrics, University of Miami School of Medicine,; Florida 33101.; Varying components of the syndrome of human immunodeficiency virus nephropathy (HIVN) have been described, the most pertinent including proteinuria/nephrotic syndrome, progressive azotemia, normal blood pressure, enlarged and hyperechoic kidneys, rapid progression to end-stage renal disease (ESRD), and no response to
The immunology of scabies.: Semin Dermatol. 1993 Mar;12(1):15-21. Unique Identifier : AIDSLINE MED/93237047; Cabrera R; Agar A; Dahl MV; Department of Dermatology, University of Chile School of; Medicine, Santiago.; Individuals with scabies react to bites by generating a cell-mediated immune response at the bite site. This elicits a very itchy papule that is often excoriated. Sometimes ulcerated papules, vasculitis, and nodules develop as a result of other immunologic reactions in skin. Immunologic reactions mediated by antibodie
Scabies research: another dimension.: Semin Dermatol. 1993 Mar;12(1):34-8. Unique Identifier : AIDSLINE MED/93237051; Estes SA; Estes J; The life cycle of canine scabies has been studied extensively. Currently studies are focusing on mite behavior, physiological requirements, host specificity, mite survival, and clinical complications of scabies. Investigations are giving insight into immunologic responses to infestation and cross-reactivity with house
Scabies in AIDS.: Semin Dermatol. 1993 Mar;12(1):9-14. Unique Identifier : AIDSLINE MED/93237056; Orkin M; Department of Dermatology, University of Minnesota, Robbinsdale; 55422.; Human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) will be the most common disease triggering crusted (Norwegian) scabies. Scabies should be suspected in any atypical itching (or non) rash in HIV/AIDS patients. Attempt to prove the diagnosis by doing a skin scraping, or if negative, a skin bio
Is HIV infection associated with an increase in the prevalence of cervical neoplasia?: Br J Obstet Gynaecol. 1993 Feb;100(2):149-53. Unique Identifier : AIDSLINE MED/93237180; Smith JR; Kitchen VS; Botcherby M; Hepburn M; Wells C; Gor D; Forster SM; Harris JR; Steer P; Mason P; Department of Obstetrics and Gynaecology, Charing Cross and; Westminster Medical School, London, UK.; OBJECTIVE: To test the hypotheses: (1) that HIV infection predisposes to cervical intraepithelial neoplasia (CIN); (2) that this CIN is a result of HIV related immunosuppression; and (3) that this CIN is a result of immunosuppression causing increased expression of the potentially oncogenic viruses, human papilloma vi
A developmental approach to sexuality education: implications for medical practice.: J Adolesc Health. 1993 Mar;14(2):109-14. Unique Identifier : AIDSLINE MED/93237261; Croft CA; Asmussen L; Division of Child and Adolescent Research, American Academy of; Pediatrics, Elk Grove Village, Illinois.; Medical professionals are increasingly expected to address issues of sexuality and acquired immunodeficiency syndrome (AIDS) with young patients and their parents. Focus group interviews were conducted with parents (n = 43) and adolescents (n = 800) to determine the preferred physician role regarding families and sexu
A pilot study of AIDS education and counseling of high-risk adolescents in an office setting.: J Adolesc Health. 1993 Mar;14(2):115-9. Unique Identifier : AIDSLINE MED/93237262; Mansfield CJ; Conroy ME; Emans SJ; Woods ER; Division of Adolescent and Young Adult Medicine, Harvard Medical; School, Boston, Massachusetts.; Little is known about interventions in office practices aimed toward reducing behaviors that put adolescents at risk for human immunodeficiency virus (HIV) acquisition. We therefore targeted a pilot study of HIV education and counseling to high-risk adolescents. Ninety adolescent patients (mean age, 17.6 +/- 2.0 years
Changes in adolescents' knowledge and attitudes about AIDS over the course of the AIDS epidemic.: J Adolesc Health. 1993 Mar;14(2):85-90. Unique Identifier : AIDSLINE MED/93237267; Zimet GD; DiClemente RJ; Lazebnik R; Anglin TM; Ellick EM; Williams P; Department of Pediatrics, Case Western Reserve University School; of Medicine, Cleveland, OH.; We compared AIDS-related attitudes of junior and senior high school students from 1988 to 1991 and across grade level to examine how effectively schools are addressing AIDS. Attitudes measured included knowledge and social anxiety about AIDS, as well as perceptions of vulnerability to HIV infection. Junior high school
Human immunodeficiency virus type 1 (HIV-1) fusion with model membranes: kinetic analysis and the role of lipid composition, pH and divalent cations.: Biochim Biophys Acta. 1993 Apr 22;1147(2):223-36. Unique Identifier : AIDSLINE MED/93237306; Larsen CE; Nir S; Alford DR; Jennings M; Lee KD; Duzgunes N; Cancer Research Institute, University of California, San; Francisco.; The kinetics and extent of HIV-1 fusion with model membranes was studied. HIV-1 was labeled with octadecyl rhodamine B chloride, and fusion was monitored continuously as the dilution of the probe into target membranes. The results were analyzed by a mass action model which yielded good simulations and predictions for
Perspectives on linkage of primary health care and substance abuse treatment [editorial]: J Addict Dis. 1993;12(2):1-8. Unique Identifier : AIDSLINE MED/93237329; Levin SM; Trumble JG; Edmunds M; Statman JM; Petersen RC
Women at high risk of HIV infection from drug use.: J Addict Dis. 1993;12(2):77-86. Unique Identifier : AIDSLINE MED/93237338; Wallace ME; Galanter M; Lifshutz H; Krasinski K; Department of Psychiatry, New York University Medical Center, NY; 10016.; The purpose of this project was to study women at high risk for contracting AIDS from intravenous drug use or from sexual contact with addicts. Characteristics of the population, differences between HIV+ and HIV- women, substance abuse in primary caretakers of this high risk population, and changes in drug use when le
Factors associated with hepatitis B infection.: Int J STD AIDS. 1993 Mar-Apr;4(2):102-6. Unique Identifier : AIDSLINE MED/93237355; Hart G; STD Control Branch, South Australia.; Men and women patients not previously immunized or tested, attending the Adelaide (South Australia ) STD clinic from 1988-1991, were tested for hepatitis B infection, and potential risk factors detected by multiple logistic regression. Of 7055 men and 3425 women patients tested 8
Contraceptive practices in HIV seropositive females in Ireland.: Int J STD AIDS. 1993 Mar-Apr;4(2):107-9. Unique Identifier : AIDSLINE MED/93237356; Murphy D; Lynch M; Desmond N; Mulcahy FM; Department of Genitourinary Medicine, St James's Hospital,; Dublin, Ireland.; A questionnaire was administered to a cohort of 130 HIV seropositive women attending the Department of Genitourinary Medicine, St James s Hospital, Dublin, in order to establish their current contraceptive practices. Forty (42%) of the sexually active women did not use reliable contraception; 55 (57%) used a method re
Roxithromycin compared to doxycycline in the treatment of genital chlamydial infection and non-specific urethritis.: Int J STD AIDS. 1993 Mar-Apr;4(2):110-3. Unique Identifier : AIDSLINE MED/93237357; Lidbrink P; Bygdeman S; Emtestam L; Gajecki M; Lapins J; Weden U; Department of Dermato-Venereology, Karolinska Institute, Huddinge; University Hospital, Sweden.; A single-blind randomized follow-up study was conducted to evaluate the efficacy and tolerance of roxithromycin 300 mg once a day compared to doxycycline 200 mg day 1 and 100 mg day 2-10 in the treatment of genital chlamydial infection in men and women and non-specific urethritis (NSU) in men. A total of 211 patients
Restricting personal behaviour: case studies on legal measures to prevent the spread of HIV.: Int J STD AIDS. 1993 Mar-Apr;4(2):114-7. Unique Identifier : AIDSLINE MED/93237358; Woodhouse DE; Muth JB; Potterat JJ; Riffe LD; El Paso County Department of Health and Environment, Colorado; Springs, CO 80910.; People infected with HIV who persist in exposing others to infection through negligent, reckless, or criminal activity create a legal and ethical dilemma for public officials. Protection of the public health requires balancing the rights of infected people with the expectations of society. When reasonable efforts fail
Anonymized sero-survey of HIV in a genitourinary medicine clinic population.: Int J STD AIDS. 1993 Mar-Apr;4(2):118-20. Unique Identifier : AIDSLINE MED/93237359; Drake SM; Skidmore SJ; Ratcliffe D; Radcliffe K; Shahmanesh M; White D; Department of Genito-urinary Medicine, East Birmingham Hospital; NHS Trust, Bordesley Green, UK.; An anonymized sero-survey of the prevalence of HIV antibody was performed at an inner city Genitourinary medicine clinic in Birmingham. In 1991 8686 patients undergoing routine serological syphilis tests were anonymously tested for HIV antibodies once during the year. Demographic information was recorded for each samp
Investigation of haematospermia [letter; comment]: Int J STD AIDS. 1993 Mar-Apr;4(2):121. Unique Identifier : AIDSLINE MED/93237360; Higgins SP; Chandiok S
Is pediculosis pubis a recurrent disease in some men? [letter]: Int J STD AIDS. 1993 Mar-Apr;4(2):121. Unique Identifier : AIDSLINE MED/93237361; Young SM; Fisk PG
Cervical neoplasia and sexually transmitted diseases among prostitutes in Oviedo, Spain [letter]: Int J STD AIDS. 1993 Mar-Apr;4(2):121-3. Unique Identifier : AIDSLINE MED/93237362; Palacio V; de Sanjose S; Vazquez S; Puente M; Vazquez F; Bosch FX
The incubation period of first episode genital herpes [letter]: Int J STD AIDS. 1993 Mar-Apr;4(2):122-3. Unique Identifier : AIDSLINE MED/93237363; Huengsberg M; Thin RN
Streptococci and the genital tract [editorial]: Int J STD AIDS. 1993 Mar-Apr;4(2):63-6. Unique Identifier : AIDSLINE MED/93237364; Rowen D; Streptococci of Lancefield Group B (GBS) are known to cause maternal sepsis and neonatal infection, whereas streptococci Lancefield Group A (GAS) cause vulvo-vaginitis in both children and adults. Prevalence of SGB colonization of the lower genital tract of normal women is between 4-18%, with higher rates found in hos
The role of aerosol pentamidine prophylaxis [editorial] [see comments]: Int J STD AIDS. 1993 Mar-Apr;4(2):67-9. Unique Identifier : AIDSLINE MED/93237365; Ong EL; Pneumocystis carinii pneumonia (PCP) is the most frequent opportunistic infection in patients with AIDS, occurring in 80% and recurring in 50% of patients within 12 months of the first episode. Prophylaxis for PCP is recommended if the CD4+ cell count is
A review and update on adult syphilis, with particular reference to its treatment [editorial]: Int J STD AIDS. 1993 Mar-Apr;4(2):70-82. Unique Identifier : AIDSLINE MED/93237366; Goldmeier D; Hay P; Syphilis has become less common in Europe in the last decade, but has once again become a major problem in the USA, and remains so in many developing countries. Several treponemal genes have now been cloned and expressed in Escherichia coli, allowing study of treponemal proteins. The importance of cell mediated immuni
Case definitions for paediatric AIDS: the Zambian experience.: Int J STD AIDS. 1993 Mar-Apr;4(2):83-5. Unique Identifier : AIDSLINE MED/93237367; Chintu C; Malek A; Nyumbu M; Luo C; Masona J; DuPont HL; Zumla A; Department of Paediatrics, University Teaching Hospital, Lusaka,; Zambia.; For the purpose of surveillance of the acquired immunodeficiency syndrome (AIDS) in developing countries, the World Health Organization (WHO) has recommended criteria for the clinical case definition of AIDS in adults and children. In a preliminary examination of children in
How often do condoms break or slip off in use?: Int J STD AIDS. 1993 Mar-Apr;4(2):90-4. Unique Identifier : AIDSLINE MED/93237369; Richters J; Donovan B; Gerofi J; Department of Public Health, University of Sydney, NSW,; Australia.; Men attending 3 sexually transmissible disease clinics and a university health service in Sydney were given a questionnaire asking how many condoms they had used in the past year and how many broke during application or use or slipped off. Respondents were 544 men aged 18 to 54 years. Of these, 402 men reported using
Sexual behaviour and use of the condom by men attending gay bars and clubs in Glasgow and Edinburgh.: Int J STD AIDS. 1993 Mar-Apr;4(2):95-8. Unique Identifier : AIDSLINE MED/93237370; Gruer LD; Ssembatya-Lule G; HIV and Addictions Resource Centre, Ruchill Hospital, Glasgow,; UK.; How widespread are the safer forms of sexual behaviour reportedly adopted by male homosexuals in recent years? A questionnaire was completed by 173 and 83 gay men attending gay bars and clubs in Edinburgh and Glasgow respectively. Comparisons were made between those who reported using the condom (n = 137, [54%]) and t
Determining the prevalence of neurosyphilis in a cohort co-infected with HIV.: Int J STD AIDS. 1993 Mar-Apr;4(2):99-101. Unique Identifier : AIDSLINE MED/93237371; Brandon WR; Boulos LM; Morse A; Louisiana State University Medical Center, Department of; Medicine/Section of HIV, New Orleans 70112.; A retrospective study of 767 HIV positive patients from a large urban public hospital, 238 of whom were co-infected with syphilis, was performed to determine the prevalence of neurosyphilis. A prevalence of 3% of neurosyphilis in the co-infected cohort was demonstrated. The 7 cases of neurosyphilis ascertained were of
Cortical astrocytosis in juvenile rhesus monkeys infected with simian immunodeficiency virus.: Neuroreport. 1993 Mar;4(3):263-6. Unique Identifier : AIDSLINE MED/93237481; Weihe E; Nohr D; Sharer L; Murray E; Rausch D; Eiden L; Department of Anatomy, University of Mainz, Germany.; The pattern of expression of GFAP immunoreactivity in astrocytes of the juvenile rhesus monkey cortex was examined following infection with simian immunodeficiency virus (SIV). Blocks of cerebral cortex plus subjacent white matter from saline- and formalin-perfused brain were examined by peroxidase-linked immunochemic
Letter from Ethiopia.: Natl Med J India. 1993 Mar-Apr;6(2):91. Unique Identifier : AIDSLINE MED/93237833; King M
Physician infection and its consequences [letter; comment]: Can Med Assoc J. 1993 May 1;148(9):1445-6. Unique Identifier : AIDSLINE MED/93238165; Parker JE
Of AIDS and other plagues [letter]: Can Med Assoc J. 1993 May 1;148(9):1448, 1450. Unique Identifier : AIDSLINE MED/93238168; Hontela S
Tuberculosis in the 1990s: current implications for dentistry.: Compendium. 1993 Mar;14(3):276, 78, 80-82 passim. Unique Identifier : AIDSLINE MED/93238245; Molinari JA; Cottone JA; Chandrasekar PH; Department of Biomedical Sciences, University of Detroit Mercy; School of Dentistry, Michigan.
Sexually transmitted diseases in the age of AIDS.: Ceylon Med J. 1993 Mar;38(1):12-4. Unique Identifier : AIDSLINE MED/93238322; Wimalawansa SJ; Hammersmith Hospital, London.; Sexually transmitted diseases (STD) are common illnesses in the world. There is at least one new sexually transmitted disease consultation for every 100 persons a year in industrialised countries. Today the World Health Organisation estimates that there are 250 million new cases of STD every year world-wide, and over
Some complications of the therapy of hemorrhagic disorders.: Dis Mon. 1993 May;39(5):301-54. Unique Identifier : AIDSLINE MED/93238566; Ratnoff OD; Department of Medicine, School of Medicine, Case Western Reserve; University, University Hospitals of Cleveland, Ohio.; The principal mode for treating disorders of hemostasis is correction of the patient s functional defect by transfusions of appropriate fractions of normal plasma or transfusions of platelets. Two major complications of such therapy are the transmission of infectious diseases, particularly hepatitis and the acquired i
Diseases and drug-related interventions affecting host defence.: Eur J Clin Microbiol Infect Dis. 1993;12 Suppl 1:S36-41. Unique Identifier : AIDSLINE MED/93238785; de Marie S; Department of Clinical Microbiology, University Hospital; Rotterdam/Dijkzigt, The Netherlands.; Recognition of an impaired immune system has implications for the diagnosis, treatment and outcome of infections. Not only the type of immunological dysfunction but also the degree of the dysfunction is important. A review is presented of the systemic diseases and immunosuppressive agents which may result in defects i
Fungal and bacterial infections in the immunocompromised host.: Eur J Clin Microbiol Infect Dis. 1993;12 Suppl 1:S42-8. Unique Identifier : AIDSLINE MED/93238786; Rubin RH; Infectious Disease Unit, Massachusetts General Hospital, Boston; 02114.; As the number of immunocompromised patients increases due to the spread of the AIDS epidemic and the successes being achieved with transplantation, cancer chemotherapy and immunosuppressive therapy, increased attention is being turned to the prevention and treatment of the infections that afflict these individuals. Th
The fate of human peripheral blood lymphocytes after transplantation into SCID mice.: Eur J Immunol. 1993 May;23(5):1023-8. Unique Identifier : AIDSLINE MED/93238854; Martino G; Anastasi J; Feng J; Mc Shan C; DeGroot L; Quintans J; Grimaldi LM; Department of Neurology, University of Milano, IRCCS H. San; Raffaele, Milano, Italy.; Human peripheral blood lymphocytes (hu-PBL) can be adoptively transferred by intraperitoneal injection into mice with severe combined immunodeficiency (SCID). The transplanted lymphocytes can produce immunoglobulin (Ig), respond to antigens, and survive for months in this chimeric model (hu-PBL SCID). However, whether
Human neuroblastoma cells produce the NF-kappa B-like HIV-1 transcription activator during differentiation.: FEBS Lett. 1993 Apr 26;321(2-3):201-4. Unique Identifier : AIDSLINE MED/93238954; Kurata S; Wakabayashi T; Ito Y; Miwa N; Ueno R; Marunouchi T; Kurata N; Medical Research Institute, Tokyo Medical and Dental University,; Japan.; Human neuroblastoma GOTO and IMR32 cells differentiate into neural cells on treatment with 5-BrdU. Here we report that in association with differentiation induced by 5-BrdU, the transcription of HIV-1 was activated in both neuroblastoma cell lines. An NF-kappa B-like factor was also found to be produced in association
HIV infection and Norwegian general practitioners: does fear affect knowledge?: Fam Pract. 1993 Mar;10(1):1-7. Unique Identifier : AIDSLINE MED/93239008; Voltersvik P; Rise J; Laerum E; Division of Infectious Disease Prevention and Control, Bergen; Health Authority, Haukeland Hospital, Norway.; The objective was to study the dimensionality of knowledge among general practitioners in Norway about transmission of HIV and what factors influence the degree of knowledge. Data were collected by a mailed questionnaire. Independent variables were experience of HIV, acquisition of
Stuck with the patient--what would my colleague have done? A videorecorded consultation experiment with an actor simulating as the same patient for different doctors.: Fam Pract. 1993 Mar;10(1):43-5. Unique Identifier : AIDSLINE MED/93239014; Aaraas I; Lundevall S; Njolstad I; Melbye H; Institute of Community Medicine, University of Tromso, Norway.; The aim of the experiment, in which four general practitioners met an actress who played a patient, was to explore how different doctors approach an identical patient problem. According to the patient role the actress had two reasons for encounter: (i) tachycardia and (ii) fear of HIV infection, which she had great di
Barriers to general practitioners caring for patients with HIV/AIDS.: Fam Pract. 1993 Mar;10(1):8-13. Unique Identifier : AIDSLINE MED/93239022; Clarke AE; Department of Public Health and Policy, London School of Hygiene; and Tropical Medicine, UK.; This paper describes some of the barriers to caring for people with HIV and AIDS by general practitioners. It is based on a review of the literature and on interviews with individuals. The first section examines the reasons given by interviewees for their involvement in HIV and AIDS care. The next section discusses th
Cancer in Kampala, Uganda, in 1989-91: changes in incidence in the era of AIDS.: Int J Cancer. 1993 Apr 22;54(1):26-36. Unique Identifier : AIDSLINE MED/93239378; Wabinga HR; Parkin DM; Wabwire-Mangen F; Mugerwa JW; Department of Pathology, Makerere Medical School, Kampala,; Uganda.; Re-establishment of the cancer registry in Kyadondo County, Uganda , has allowed estimation of incidence rates for the period September 1989 to December 1991. The results are compared with earlier data from the same area, and from other African cancer registries. The most striking f
Suicidal behaviour in people infected with human immunodeficiency virus: a literature review.: Int J Soc Psychiatry. 1993 Spring;39(1):64-70. Unique Identifier : AIDSLINE MED/93239418; Starace F; Department of Psychiatry I, University of Naples, Italy.; Suicidal acts seem to be more frequent in AIDS patients than in the general population: nevertheless, the interpretation of these findings remains uncertain, because an increased risk of suicide has been found in some groups at risk of HIV infection (homosexuals, i.v. drug users) irrespective of the presence of HIV in
Polypharmacy: dangers of multiple-drug therapy in patients with immunodeficiency virus infection [letter; comment]: Home Healthc Nurse. 1993 Mar-Apr;11(2):68-9. Unique Identifier : AIDSLINE MED/93239478; Ungvarski P; Schmidt J
Immigrants infected with the human immunodeficiency virus (HIV) [editorial]: J Am Osteopath Assoc. 1993 Apr;93(4):431. Unique Identifier : AIDSLINE MED/93239526
Using convergent combination therapy, researchers stopped the human immunodeficiency virus (HIV) from reproducing in test tubes [editorial]: J Am Osteopath Assoc. 1993 Apr;93(4):431. Unique Identifier : AIDSLINE MED/93239527
Another skin manifestation of HIV infection [letter; comment]: J Am Osteopath Assoc. 1993 Apr;93(4):513-4. Unique Identifier : AIDSLINE MED/93239536; Woolery WA
Psychophysiologists and the AIDS epidemic: can we help?: Int J Psychophysiol. 1993 Feb;14(2):99-101. Unique Identifier : AIDSLINE MED/93239574; Andreassi JL; Baruch College, City University of New York, NY 10010.
Pyomyositis in patients who have the human immunodeficiency virus. Case report and review of the literature.: J Bone Joint Surg Am. 1993 Apr;75(4):588-92. Unique Identifier : AIDSLINE MED/93239758; Rodgers WB; Yodlowski ML; Mintzer CM; Department of Orthopedic Surgery, Brigham and Women's Hospital,; Boston, Massachusetts 02115.
Sexually transmitted diseases in a HIV infected patient.: J Dermatol. 1993 Mar;20(3):171-4. Unique Identifier : AIDSLINE MED/93239909; Ishii N; Ichiyama S; Nakajima H; Ito A; Department of Dermatology, Yokohama City University School of; Medicine, Japan.; We report a case of HIV infection with herpes simplex, syphilis, and condyloma acuminatum in a 66-year-old heterosexual man. The patient was an asymptomatic carrier (group II) of HIV infection. Herpes simplex on his penis was controlled by aciclovir. Secondary syphilis was treated with penicillin G, after which skin l
Where we stand with AIDS [letter; comment]: J Am Coll Dent. 1993 Spring;60(1):4. Unique Identifier : AIDSLINE MED/93239927; Luria S
A fire on the AIDS ward.: Infect Control Hosp Epidemiol. 1993 Mar;14(3):151-2. Unique Identifier : AIDSLINE MED/93239972; McKinney WP; Milwaukee County Medical Complex, WI.
Hospital may lose federal funding for discriminating against HIV-positive healthcare worker [news]: Infect Control Hosp Epidemiol. 1993 Mar;14(3):177. Unique Identifier : AIDSLINE MED/93239978
New TB control recommendations call for four-drug regime and HIV testing of TB patients [news]: Infect Control Hosp Epidemiol. 1993 Mar;14(3):177-8. Unique Identifier : AIDSLINE MED/93239979
NIOSH to expand research on workplace transmission of infectious diseases [news]: Infect Control Hosp Epidemiol. 1993 Mar;14(3):179. Unique Identifier : AIDSLINE MED/93239981
AHA issues revised AIDS/HIV recommendations [news]: Infect Control Hosp Epidemiol. 1993 Apr;14(4):237. Unique Identifier : AIDSLINE MED/93239994
Court orders AIDS patient to pay exposed healthcare worker [news]: Infect Control Hosp Epidemiol. 1993 Apr;14(4):237. Unique Identifier : AIDSLINE MED/93239995
Glaxo, Inc., releases video on preventing occupational HIV infection in healthcare workers [news]: Infect Control Hosp Epidemiol. 1993 Apr;14(4):238. Unique Identifier : AIDSLINE MED/93239996
Guidelines available for managing TB and HIV in the workplace [news]: Infect Control Hosp Epidemiol. 1993 Apr;14(4):238. Unique Identifier : AIDSLINE MED/93239997
New York begins 24-hour hotline for AIDS clinical drug trial information [news]: Infect Control Hosp Epidemiol. 1993 Apr;14(4):238. Unique Identifier : AIDSLINE MED/93239998
New CDC recommendations call for voluntary testing of hospital patients [news]: Infect Control Hosp Epidemiol. 1993 Apr;14(4):239. Unique Identifier : AIDSLINE MED/93239999
Enhanced susceptibility of blood monocytes from patients with pulmonary tuberculosis to productive infection with human immunodeficiency virus type 1.: J Exp Med. 1993 May 1;177(5):1511-6. Unique Identifier : AIDSLINE MED/93240134; Toossi Z; Sierra-Madero JG; Blinkhorn RA; Mettler MA; Rich EA; Department of Medicine, Case Western Reserve University,; Cleveland, Ohio.; Blood monocytes from patients with active pulmonary tuberculosis and age-matched healthy purified protein derivative-reactive donors were infected with human immunodeficiency virus type 1 (HIV-1)JR-FL in vitro to assess their susceptibility to productive infection by HIV-1. HIV-1 p24 levels (enzyme-linked immunosorben
Prevention of HIV infection in women.: J Obstet Gynecol Neonatal Nurs. 1993 Mar-Apr;22(2):128-34. Unique Identifier : AIDSLINE MED/93240294; Nolte S; Sohn MA; Koons B; Abington Memorial Hospital, PA 19001.; The number of HIV-infected women in the United States has continued to rise. Although risk-reducing behaviors such as condom use, partner selection, partner reduction, and safe sex practices have been identified, women continue to engage in high-risk activities. Nurses need to offer te
Adult T-cell leukemia with initial presentation as sinonasal lymphoma: report of two cases.: J Oral Maxillofac Surg. 1993 May;51(5):584-7. Unique Identifier : AIDSLINE MED/93240327; Kurihara K; Mizuseki K; Kono H; Chikamori Y; Department of Pathology, Uwajima City Hospital, Uwajima Ehime,; Japan.
Human T lymphotropic virus I, myelopathy, polymyositis and synovitis [letter; comment]: J Rheumatol. 1993 Mar;20(3):594-5. Unique Identifier : AIDSLINE MED/93240467; McKown K; Trigg L; Cremer M
Intracellular delivery of bioactive AZT nucleotides by aryl phosphate derivatives of AZT.: J Med Chem. 1993 Apr 16;36(8):1048-52. Unique Identifier : AIDSLINE MED/93240490; McGuigan C; Pathirana RN; Balzarini J; De Clercq E; Department of Chemistry, University of Southampton, Highfield,; U.K.; Novel aryl phosphate derivatives of the anti-HIV nucleoside analogue AZT have been prepared by phosphorochloridate chemistry. These materials were designed to act as membrane-soluble prodrugs of the bioactive free nucleotides. In vitro evaluation reve
Inhibitors of the protease from human immunodeficiency virus: synthesis, enzyme inhibition, and antiviral activity of a series of compounds containing the dihydroxyethylene transition-state isostere.: J Med Chem. 1993 Apr 16;36(8):941-52. Unique Identifier : AIDSLINE MED/93240497; Thaisrivongs S; Turner SR; Strohbach JW; TenBrink RE; Tarpley WG; McQuade TJ; Heinrikson RL; Tomasselli AG; Hui JO; Howe WJ; Department of Medicinal Chemistry, Upjohn Laboratories, Upjohn; Company, Kalamazoo, Michigan 49001.; A number of potential HIV protease inhibitory peptides that contain the dihydroxyethylene isostere were prepared and evaluated for their enzyme binding affinity and antiviral activity in cell cultures. From the template of a previously reported active peptide A, modifications at the N- and C-terminal groups were asses
Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries.: J Mol Biol. 1993 Apr 5;230(3):812-23. Unique Identifier : AIDSLINE +; Barbas CF 3d; Collet TA; Amberg W; Roben P; Binley JM; Hoekstra D; Cababa D; Jones TM; Williamson RA; Pilkington GR; et al; Department of Immunology, Scripps Research Institute, La Jolla,; CA 92037.; A large number (33) of human Fab fragments reacting with HIV-1 surface glycoprotein gp120 have been generated by selection from a combinatorial IgG1 kappa library displayed on the surface of phage. The library was prepared from a long term asymptomatic HIV-seropositive donor. Analysis of the sequences from these Fabs
Short-term declines in CD4 levels associated with cocaine use in HIV-1 seropositive, minority injecting drug users.: J Natl Med Assoc. 1993 Apr;85(4):293-6. Unique Identifier : AIDSLINE MED/93240575; Siddiqui NS; Brown LS Jr; Makuch RW; Division of Medical Services, Evaluation and Research, Addiction; Research and Treatment Corporation, Brooklyn, New York 11201.; This study evaluates the association of cocaine use with short-term change in CD4 counts among human immunodeficiency virus type 1 (HIV-1) seropositive, minority injecting drug users prior to the introduction of zidovudine ( AZT ). Ninety-eight HIV-1 se
[Levels of serum lactate dehydrogenase and its isozymes with relation to clinical features of pneumocystis carinii pneumonia in acquired immunodeficiency syndrome patients]: Rinsho Ketsueki. 1993 Mar;34(3):294-300. Unique Identifier : AIDSLINE MED/93240698; Tanaka A; Yamagishi T; Satou T; Yorifuji H; Fukutake K; Fujimaki M; Department of clinical pathology, Tokyo Medical College.; The clinical courses of 9 patients with acquired immunodeficiency syndrome (AIDS) complicated by pneumocystis carinii pneumonia (PCP) were followed to investigate the clinical significance of the measurement of various parameters such as serum lactate dehydrogenase (LDH). The mean duration of symptoms before diagnosis
Selected behaviors that increase risk for HIV infection, other sexually transmitted diseases, and unintended pregnancy among high school students--United States, 1991.: J Sch Health. 1993 Feb;63(2):116-8. Unique Identifier : AIDSLINE MED/93240819
Reassuring patients about infection control. TMA Communications and Public Service Committee.: J Tenn Med Assoc. 1993 Apr;86(4):162. Unique Identifier : AIDSLINE MED/93240847; Bowers R
[Multicenter study of HTLV-I and HTLV-II infection in Spain. Spanish Group for the Study of HTLV-II/II Infection (see comments)]: Med Clin (Barc). 1993 Apr 3;100(13):492-6. Unique Identifier : AIDSLINE MED/93240904; Soriano V; Calderon E; Cilla G; Aguilera A; Merino F; Gutierrez M; Servicio de Enfermedades Infecciosas, Centro de Investigaciones; Clinicas, Instituto de Salud Carlos III, Madrid.; BACKGROUND: Human T-lymphotropic viruses type I (HTLV-I) and type II (HTLV-II) infections have been related to lymphoproliferative disorders and subacute neurological diseases. Screening blood donors for specific HTLV-I/II antibody has been implemented in Japan ,
[Campylobacter jejuni bacteremia in patients infected with HIV (letter; comment)]: Med Clin (Barc). 1993 Apr 3;100(13):514. Unique Identifier : AIDSLINE MED/93240909; Chaves F; Dronda F; Gonzalez-Lopez A
[HIV-positive Africans spread the infection. Many of them ignore the rules of protection against the infection (see comments)]: Lakartidningen. 1993 Apr 14;90(15):1478-81. Unique Identifier : AIDSLINE MED/93240953; Christenson B; Lundbergh P; Karolinska sjukhuset, Stockholm.
Medicine in tropical Australia [published erratum appears in Med J Aust 1993 Jun 21;158(12):868] [see comments]: Med J Aust. 1993 May 3;158(9):609, 612-5. Unique Identifier : AIDSLINE MED/93241094; Currie B; Menzies School of Health Research, Casuarina, NT.; In the unique environment of Australia s tropical north there are endemic diseases inherited from Gondwana, others introduced from the north and from Europe, and a wide range of particularly venomous animals. There is continuing disparity in morbidity and mortality between Aboriginal people and other Australians in tr
Biopsychosocial aspects of AIDS.: New Dir Ment Health Serv. 1993 Spring;(57):51-60. Unique Identifier : AIDSLINE MED/93241128; Field HL; Division of Consultation-Liaison Psychiatry, Jefferson Medical; College, Philadelphia.
Update: investigations of persons treated by HIV-infected health-care workers--United States.: MMWR Morb Mortal Wkly Rep. 1993 May 7;42(17):329-31, 337. Unique Identifier : AIDSLINE MED/93241139; Previous reports have described transmission of human immunodeficiency virus (HIV) to five persons (patients A, B, C, E, and G) during receipt of care from an HIV-infected dentist in Florida and other investigations of patients who were treated by HIV-infected health-care workers (HCWs). This report updates these inve
Recent advances in pulmonary medicine (2) [see comments]: N Engl J Med. 1993 May 20;328(20):1462-70. Unique Identifier : AIDSLINE MED/93241233; Weinberger SE; Pulmonary and Critical Care Division, Beth Israel Hospital,; Boston, MA 02215.
Dapsone-pyrimethamine compared with aerosolized pentamidine as primary prophylaxis against Pneumocystis carinii pneumonia and toxoplasmosis in HIV infection. The PRIO Study Group.: N Engl J Med. 1993 May 27;328(21):1514-20. Unique Identifier : AIDSLINE MED/93241257; Girard PM; Landman R; Gaudebout C; Olivares R; Saimot AG; Jelazko P; Gaudebout C; Certain A; Boue F; Bouvet E; et al; Institut National de la Sante et de la Recherche Medicale,; Unite 13, Paris, France.; BACKGROUND. Pneumocystis carinii pneumonia and toxoplasmic encephalitis are frequent life-threatening opportunistic infections in patients with human immunodeficiency virus (HIV) infection. Primary prophylaxis against P. carinii pneumonia is now common, but there are few data on regimens for primary prophylaxis agains
Comparison of atovaquone (566C80) with trimethoprim-sulfamethoxazole to treat Pneumocystis carinii pneumonia in patients with AIDS [see comments]: N Engl J Med. 1993 May 27;328(21):1521-7. Unique Identifier : AIDSLINE MED/93241258; Hughes W; Leoung G; Kramer F; Bozzette SA; Safrin S; Frame P; Clumeck N; Masur H; Lancaster D; Chan C; et al; Department of Infectious Diseases, St. Jude Children's Research; Hospital, Memphis, Tenn. 38105.; BACKGROUND. Both trimethoprim-sulfamethoxazole and pentamidine are effective as treatments for Pneumocystis carinii pneumonia, but adverse effects frequently limit their use. Atovaquone (566C80) is a new hydroxynaphthoquinone with activity against P. carinii. METHODS. We conducted a double-blind, multicenter study in
Prevention and treatment of Pneumocystis pneumonia [letter; comment]: N Engl J Med. 1993 May 27;328(21):1569. Unique Identifier : AIDSLINE MED/93241276; Ong EL; Mandal BK
15 drug companies to share data on AIDS therapies [news]: Nature. 1993 Apr 29;362(6423):780. Unique Identifier : AIDSLINE MED/93241285; Gershon D
Montagnier to assess French AIDS effort [news]: Nature. 1993 May 6;363(6424):9. Unique Identifier : AIDSLINE MED/93241326
Costing the HIV/AIDS epidemic [letter; comment]: N Z Med J. 1993 Apr 28;106(954):166. Unique Identifier : AIDSLINE MED/93241625; Tobias M; Bowie RD
Who's protected? Legal, ethical issues in employing the immunosuppressed.: Occup Health Saf. 1993 Apr;62(4):76-9. Unique Identifier : AIDSLINE MED/93241648; Behling D; Guy J; Critical Care Unit, Presbyterian St. Luke's Medical Center,; Denver, CO.; There does exist a growing population of immunosuppressed people who are entering or re-entering the workforce, and their impact will be felt in the future. They present unique needs that should be addressed clearly, but the waters remain muddy. How do all remain protected and at what cost? The government has establis
[New AIDS vaccine tested in 8 countries (news)]: Nord Med. 1993;108(4):103. Unique Identifier : AIDSLINE MED/93241910
Preventing unintended teenage pregnancies.: Public Health. 1993 Mar;107(2):125-33. Unique Identifier : AIDSLINE MED/93242145; Peckham S; Institute for Health Policy Studies, University of Southampton.; A review of the literature on unplanned and teenage pregnancies was undertaken for four District Health Authorities. This work was carried out within a national context of increasing conception rates for teenage women aged 16 and under and in the knowledge that pregnant teenagers and their children tend to have poor l
[Rhodococcus equi pulmonitis in HIV+. A review of the literature and a case report]: Radiol Med (Torino). 1993 Jan-Feb;85(1-2):122-5. Unique Identifier : AIDSLINE MED/93242173; Cecconi L; Mazzuoli G; Busi Rizzi E; Schinina V; Bordi E; Tocci G; Servizio di Radiologia, Ospedale Lazzaro Spallanzani, Roma.
[Herpes zoster involving multiple cranial nerves (letter)]: Rev Clin Esp. 1993 Mar;192(4):203-4. Unique Identifier : AIDSLINE MED/93242216; de la Fuente Aguado J; Bordon JM; Prieto Lopez I; Sopena Perez-Arguelles B
[Indications for intravenous immunoglobulins]: Rev Med Suisse Romande. 1993 Mar;113(3):179-82. Unique Identifier : AIDSLINE MED/93242306; Spertini F; Division d'immunologie et d'allergie, CHUV, Lausanne.
Hospital won't limit duties of HIV+ pharmacist [news]: RN. 1993 Apr;56(4):18, 20. Unique Identifier : AIDSLINE MED/93242323
Public perceptions about AIDS are at odds with facts [news]: RN. 1993 Apr;56(4):20. Unique Identifier : AIDSLINE MED/93242324
Sorbitol isn't always a sweet deal [letter]: RN. 1993 Apr;56(4):73. Unique Identifier : AIDSLINE MED/93242334; Sheehan CJ
Congress may hang up on AIDS hotline [news]: Science. 1993 Apr 30;260(5108):611. Unique Identifier : AIDSLINE MED/93242387
Anti-permissive attitudes to lifestyles associated with AIDS.: Soc Sci Med. 1993 Apr;36(7):893-901. Unique Identifier : AIDSLINE MED/93242458; Nisbet LA; McQueen DV; Research Unit in Health and Behavioural Change, University of; Edinburgh.; AIDS is in the tradition of diseases which have given moral interpretations. One way in which this moralistic perspective may express itself is by members of the public holding high risk groups responsible for their (AIDS related) lifestyles and their considering AIDS to be a self-inflicted disease. A unique data sour
HIV transmission through social and geographic networks in Uganda.: Soc Sci Med. 1993 Apr;36(7):949-55. Unique Identifier : AIDSLINE MED/93242463; Obbo C; Chateau de la Mothe, St Aulaye, France.; Long distance drivers and prostitutes at trading centres and towns have been targeted as groups that engage in risky sexual behaviours that promote HIV transmission. While towns and stops along highways have been linked to HIV transmission, the role of small urban and rural centres have been overlooked. There is need
Prostitution and the military: planning AIDS intervention in Belize.: Soc Sci Med. 1993 Apr;36(7):965-79. Unique Identifier : AIDSLINE MED/93242465; Kane SC; Department of Criminal Justice, Indiana University, Bloomington,; IN 47405.; First world militaries based in third world countries offer an appropriate context for developing AIDS intervention models that are keyed to large-scale population movements and regional differences in HIV infection. In this work, the ethnographic concept of social interface replaces the epidemiological concept of
Facilitating support groups for professionals working with people with AIDS.: Soc Work. 1993 Mar;38(2):144-51. Unique Identifier : AIDSLINE MED/93242467; Grossman AH; Silverstein C; School of Education, Health, Nursing, and Arts Professions, New; York University, NY 10003.; Social workers, nurses, and other health care professionals who work with people with human immunodeficiency virus (HIV) or acquired immune deficiency syndrome (AIDS) are experiencing burnout from the excessive demands on their energy, strength, and resources. Support groups, with their focus on awareness, shared expe
[Contact tracing in HIV infection]: Ugeskr Laeger. 1993 Mar 22;155(12):887-90. Unique Identifier : AIDSLINE MED/93242690; Worm AM; Sorensen H; Sonniks M; Sondergaard J; Dermato-venerologisk afdeling A., Bispebjerg Hospital, Kobenhavn.; The results of contact tracing in two male and one female HIV antibody positive index cases are described. Altogether 19 sexual partners were reported, of whom 13 were traced. In one case previously unknown HIV infection was diagnosed. Contact tracing for HIV infection in
Identification of a putative cellular receptor for HTLV-I by a monoclonal antibody, Mab 34-23.: Virology. 1993 May;194(1):1-9. Unique Identifier : AIDSLINE MED/93242735; Gavalchin J; Fan N; Lane MJ; Papsidero L; Poiesz BJ; Department of Medicine, SUNY Health Science Center, New York; 13210.; The ability of HTLV-I to infect cells is presumed to be dependent, in some part, on the attachment of the virus to a target cell via a specific cell surface receptor which is, as yet, unknown. Here we present evidence that a monoclonal antibody, Mab 34-23, inhibits the binding of HTLV-I to
HIV-1 Nef protein inhibits the recruitment of AP-1 DNA-binding activity in human T-cells.: Virology. 1993 May;194(1):338-44. Unique Identifier : AIDSLINE MED/93242763; Niederman TM; Hastings WR; Luria S; Bandres JC; Ratner L; Department of Medicine, Washington University School of Medicine,; St. Louis, Missouri 63110.; The human immunodeficiency virus type 1 long terminal repeat, HIV-1-LTR, contains binding sites for several cellular transcription factors which contribute to HIV-1 gene expression. Our previous studies on the function of the HIV-1-encoded Nef protein suggested that Nef may be an inhibitor HIV-1 transcription. To dete
Mapping of the human immunodeficiency virus type 2 envelope glycoprotein CD4 binding region and fusion domain with truncated proteins expressed by recombinant vaccinia viruses.: Virology. 1993 May;194(1):37-43. Unique Identifier : AIDSLINE MED/93242769; Otteken A; Voss G; Hunsmann G; Deutsches Primatenzentrum, Abteilung fur Virologie und; Immunologie, Gottingen, Germany.; Human immunodeficiency virus type 2 (HIV-2) is more closely related to certain simian immunodeficiency viruses than to HIV-1. The HIV-1 and HIV-2 envelope (env) glycoproteins share only approximately 40% amino acid (aa) sequence homology. Additionally, HIV-1 and HIV-2 seem to differ in pathogenicity and in host range.
Double-stranded strong-stop DNA and the second template switch in human immunodeficiency virus (HIV) DNA synthesis.: Virology. 1993 May;194(1):82-8. Unique Identifier : AIDSLINE MED/93242785; Li P; Stephenson AJ; Kuiper LJ; Burrell CJ; National Centre for HIV Virology Research, Institute of Medical; and Veterinary Science, Adelaide, South Australia.; Synthesis of unintegrated retroviral DNA via reverse transcription is thought to involve two separate template switches. Minus-strand strong-stop DNA, a major product of in vitro reactions using detergent-treated virions, is synthesized prior to the first template switch. Plus-strand strong-stop DNA, which is found ba
[Cost analysis of a bone bank]: Z Orthop Ihre Grenzgeb. 1993 Jan-Feb;131(1):51-6. Unique Identifier : AIDSLINE MED/93242978; Torwesten G; Braun M; Orthopadische Klinik Volmarstein.; The costs of a bone-bank working in accordance with the guidelines of the german federal chamber of physicians are described. Establishing a bone-bank storing deep-frozen bone is not very expensive. The main costs are due to laboratory costs for excluding HIV, hepatitis, syphilis and bacterial contamination of bone gr
Resting energy expenditure in human immunodeficiency virus-infected patients: comparison between patients with and without secondary infections.: Am J Clin Nutr. 1993 May;57(5):614-9. Unique Identifier : AIDSLINE MED/93243299; Melchior JC; Raguin G; Boulier A; Bouvet E; Rigaud D; Matheron S; Casalino E; Vilde JL; Vachon F; Coulaud JP; et al; Service de nutrition Humaine, Hopital Bichat C Bernard, Paris,; France.; Resting energy expenditure (REE) was measured in 165 malnourished patients with human immunodeficiency virus infection and compared with that of 31 control subjects. Of these patients, 129 had no symptoms of secondary infections (NI), whereas 36 had evolving secondary infection (I) despite a body temperature
Helicobacter pylori prevalence in acquired immunodeficiency syndrome.: Am J Gastroenterol. 1993 May;88(5):687-90. Unique Identifier : AIDSLINE MED/93243359; Marano BJ Jr; Smith F; Bonanno CA; Department of Medicine, St. Vincent's Hospital and Medical; Center, New York, New York.; Helicobacter pylori is consistently reported with high prevalence in HIV-negative patients with chronic gastritis and active ulcer disease. This study is an evaluation of the prevalence of H. pylori in AIDS patients, and the association with chronic gastritis, erosions, and ulcer disease. Seventy-three AIDS patients r
Abdominal tuberculosis: still a potentially lethal disease.: Am J Gastroenterol. 1993 May;88(5):744-50. Unique Identifier : AIDSLINE MED/93243369; Lingenfelser T; Zak J; Marks IN; Steyn E; Halkett J; Price SK; Department of Medicine, Groote Schuur Hospital, Cape Town, South; Africa.; The findings in a 4-yr survey of 82 patients with abdominal tuberculosis are described and compared with those encountered in previous surveys. Fourteen cases of intestinal, 11 of mesenteric-lymphnodal, and 57 of peritoneal tuberculosis were identified. The disease occurred essentially in patients living under worseni
AIDS-related hepatic Kaposi's sarcoma: massive bleeding following liver biopsy.: Am J Gastroenterol. 1993 May;88(5):762-4. Unique Identifier : AIDSLINE MED/93243373; Gottesman D; Dyrszka H; Albarran J; Hilfer J; Division of Gastroenterology, Cabrini Medical Center, New York,; New York.
Implementation of a hospital policy for health care workers exposed to hepatitis or the human immunodeficiency virus.: Am J Hosp Pharm. 1993 Feb;50(2):269-75. Unique Identifier : AIDSLINE MED/93243416; Fahrner R; HIV Prevention Service, San Francisco General Hospital Medical; Center, CA 94110.; Implementation of a hospital policy for health care workers exposed to the human immunodeficiency virus (HIV) or hepatitis is discussed, using a model program established by San Francisco General Hospital (SFGH). Occupational Safety and Health Administration (OSHA) guidelines on blood-borne pathogens require a compreh
Authenticity remembered [letter]: Am J Nurs. 1993 Apr;93(4):17. Unique Identifier : AIDSLINE MED/93243432; Weber TJ
Caring for the AIDS victim: what can we learn? [editorial]: Am J Psychiatry. 1993 May;150(5):689-90. Unique Identifier : AIDSLINE MED/93243448; Gorman JM
Psychosocial impact of HIV-related caregiving on health providers: a review and recommendations for the role of psychiatry.: Am J Psychiatry. 1993 May;150(5):705-12. Unique Identifier : AIDSLINE MED/93243451; Silverman DC; Department of Psychiatry, Beth Israel Hospital, Boston, MA 02215.; OBJECTIVE: The author considers current knowledge about the stresses of HIV-related care and assesses available evidence for the presence of major occupational, physical, and psychiatric morbidity in health care providers involved in intensive HIV-related caregiving. METHOD: The review is based on anecdotal reports of
Severity of psychiatric symptoms after HIV testing.: Am J Psychiatry. 1993 May;150(5):775-9. Unique Identifier : AIDSLINE MED/93243462; Perry S; Jacobsberg L; Card CA; Ashman T; Frances A; Fishman B; HIV Clinical Research Program, Cornell University Medical; College, New York.; OBJECTIVE: The authors were interested in the psychiatric effects of serological testing for HIV and what information feasibly available at intake might predict more severe psychiatric symptoms 1 year later. METHOD: HIV testing in a private office setting was offered to adults at perceived risk for HIV infection but w
AIDS policy: position statement on confidentiality, disclosure, and protection of others. Commission on AIDS.: Am J Psychiatry. 1993 May;150(5):852. Unique Identifier : AIDSLINE MED/93243493
AIDS policy: guidelines for inpatient psychiatric units. Commission on AIDS.: Am J Psychiatry. 1993 May;150(5):853. Unique Identifier : AIDSLINE MED/93243494
Enhancement of resistance to Cryptosporidium parvum by pooled bovine colostrum during murine retroviral infection.: Am J Trop Med Hyg. 1993 Apr;48(4):519-23. Unique Identifier : AIDSLINE MED/93243502; Watzl B; Huang DS; Alak J; Darban H; Jenkins EM; Watson RR; Department of Family and Community Medicine, University of; Arizona, Tucson.; The therapeutic efficacy of pooled bovine colostrum for the control of cryptosporidiosis was investigated during murine acquired immunodeficiency syndrome in female C57Bl/6 mice. Mice were infected with LP-BM5 murine leukemia retrovirus for four months and then inoculated with Cryptosporidium parvum oocysts. Persisten
Pleural effusions in hospitalized patients with AIDS [see comments]: Ann Intern Med. 1993 Jun 1;118(11):856-9. Unique Identifier : AIDSLINE MED/93243610; Joseph J; Strange C; Sahn SA; Division of Pulmonary and Critical Care Medicine, Medical; University of South Carolina, Charleston 29425.; OBJECTIVE: To determine the incidence, cause, and characteristics of pleural effusions in hospitalized patients with the acquired immunodeficiency syndrome (AIDS). DESIGN: Retrospective. PARTICIPANTS: A total of 222 patients with AIDS hospitalized between January 1986 and January 1992 at the Medical University of Sout
Who should be screened for HIV infection? A cost-effectiveness analysis.: Arch Intern Med. 1993 May 10;153(9):1107-16. Unique Identifier : AIDSLINE MED/93243850; McCarthy BD; Wong JB; Munoz A; Sonnenberg FA; Center for Clinical Effectiveness, Henry Ford Health System,; Detroit, MI.; BACKGROUND: The advent of effective prophylactic treatments for asymptomatic persons infected with human immunodeficiency virus has led to interest in widespread screening programs. However, the costs of screening programs and therapy are high, and the prevalence of infection above which screening becomes an appropria
Fluconazole-resistant Candida albicans after long-term suppressive therapy.: Arch Intern Med. 1993 May 10;153(9):1122-4. Unique Identifier : AIDSLINE MED/93243851; Sanguineti A; Carmichael JK; Campbell K; Department of Internal Medicine, Hospital Medical Education; Program, Tucson, Ariz.; Candida albicans is generally considered to be susceptible, in vivo, to fluconazole. In the population infected with human immunodeficiency virus, recurrent bouts of oral and esophageal candidiasis have led to increasing use of fluconazole for long-term prophylaxis. With prolonged therapy, the issue of developing resi
Human immunodeficiency virus infection, dementia and the older patient.: Aust N Z J Psychiatry. 1993 Mar;27(1):9-19. Unique Identifier : AIDSLINE MED/93244026; Kernutt GJ; Price AJ; Judd FK; Burrows GD; Department of Psychiatry, University of Melbourne, Austin; Hospital, Heidelberg, Victoria.; Australian statistics have shown that 10.9% of AIDS cases have occurred in the 50 years and over age group. To date little attention has been given to the many issues surrounding HIV infection in the older population, for example, the failure to consider HIV as an aetiological factor in the older person presenting wit
Who won't tell: predictors of refusal to report number of sex partners.: Int J STD AIDS. 1993 Mar-Apr;4(2):86-9. Unique Identifier : AIDSLINE MED/93237368; Peruga A; Kofie VY; Martinez RM; Pan American Health Organization, Washington DC 20037.; Data from 1475 respondents to a telephone survey are used to examine whether those who refused to report the number of their sex partners in the 12-month period prior to the interview are more likely to engage in HIV risk behaviours than those who did report this number. Logistic regression shows that refusal is assoc
HIV transmission, travel and Thailand [letter; comment]: BMJ. 1993 Feb 6;306(6874):393-4. Unique Identifier : AIDSLINE MED/93214409; Waugh MA
HIV vaccination dilemma [letter; comment]: Nature. 1993 Mar 18;362(6417):212. Unique Identifier : AIDSLINE MED/93211472; Sabin AB
The causation of disease: HIV and AIDS [comment]: J Can Dent Assoc. 1993 Apr;59(4):351-4. Unique Identifier : AIDSLINE MED/93230468; Mathias RG; Marion SA; Epstein JB; Department of Health Care and Epidemiology, University of British; Columbia.
Central nervous system toxoplasmosis in AIDS [letter; comment]: N Engl J Med. 1993 May 6;328(18):1352-3; discussion 1354. Unique Identifier : AIDSLINE MED/93226017; Klein RS
Immunization with lentivirus-like particles elicits a potent SIV-specific recall cytotoxic T-lymphocyte response in rhesus monkeys.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):129-32. Unique Identifier : AIDSLINE MED/93207818; Shen L; Mazzara GP; DiSciullo SO; Panicali DL; Letvin NL; Harvard Medical School, New England Regional Primate Research; Center, Southborough, MA 01772.; An effective acquired immunodeficiency syndrome (AIDS) vaccine should be capable of eliciting human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte (CTL) responses. We have explored the use of lentivirus-like particles produced in mammalian cells infected with a recombinant vaccinia virus to immunize for
The progression of HIV disease in a haemophilic cohort followed for 12 years.: Br J Haematol. 1993 Feb;83(2):330-3. Unique Identifier : AIDSLINE MED/93208018; Sabin C; Phillips A; Elford J; Griffiths P; Janossay G; Lee C; Department of Haematology, Royal Free Hospital and School of; Medicine, London.; A cohort of haemophilic patients who seroconverted to HIV-1 between October 1979 and July 1985 has been followed to 1 January 1992. The median age at initial seropositivity was 24 years with a range of 2-77 years. By January 1992, 38/111 (34%) had developed AIDS and 39/111 (35%) had died (four of liver failure includi
CDC revises AIDS case definition [news]: Clin Pharm. 1993 Apr;12(4):254. Unique Identifier : AIDSLINE MED/93208990
Detection of feline immunodeficiency virus in saliva and plasma by cultivation and polymerase chain reaction.: J Clin Microbiol. 1993 Mar;31(3):494-501. Unique Identifier : AIDSLINE MED/93210064; Matteucci D; Baldinotti F; Mazzetti P; Pistello M; Bandecchi P; Ghilarducci R; Poli A; Tozzini F; Bendinelli M; Department of Biomedicine, University of Pisa, Italy.; The rates of feline immunodeficiency virus (FIV) isolation from saliva, plasma, and peripheral blood mononuclear cells (PBMC) of infected cats were compared; isolation rates were 18, 14, and 81%, respectively, in naturally infected cats and 25, 57, and 100%, respectively, in experimentally infected animals. There was
Antiretroviral therapy.: J La State Med Soc. 1993 Mar;145(3):81-2. Unique Identifier : AIDSLINE MED/93210404; Bucher GG; LSU Medical Center, Medical Center of Louisiana, New Orleans.
Relative susceptibility of beef and dairy calves to infection by bovine leukemia virus via tabanid (Diptera: Tabanidae) feeding.: J Med Entomol. 1993 Mar;30(2):472-3. Unique Identifier : AIDSLINE MED/93210737; Hasselschwert DL; French DD; Hribar LJ; Luther DG; Leprince DJ; Van der Maaten MJ; Whetstone CA; Foil LD; Department of Entomology, Louisiana Agricultural Experiment; Station, Louisiana State University Agricultural Center, Baton; Rouge 70803.; Differences in susceptibility of beef (mixed breeds) and dairy (Holstein) calves to infection by bovine leukemia virus (BLV) were compared. Transmission was accomplished by interrupted feeding of horse flies, Tabanus fuscicostatus Hine, on a donor cow exhibiting persistent lymphocytosis. Flies were transferred individ
Transcription of retinoic acid receptor genes in transgenic mice increases CD8 T-cell subset.: Mol Biol Rep. 1993 Feb;17(2):135-42. Unique Identifier : AIDSLINE MED/93211396; Pohl J; LaFace D; Sands JF; Department of Immunology, Research Institute of Scripps Clinic,; La Jolla, Calif.; Retinoic acid (RA), a vitamin A derivative is known to have a number of effects on the immune system such as inducing cytotoxic T-lymphocytes in vivo and inducing the rejection of skin grafts. However, the molecular mechanisms of these actions are unclear. The retinoic acid receptors which belong to the steroid/thyroi
Retroviral infection coupled with tissue transplantation limits gene transfer in the chicken embryo.: Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2350-4. Unique Identifier : AIDSLINE MED/93211959; Fekete DM; Cepko CL; Department of Genetics, Harvard Medical School, Boston, MA 02115.; Gene transfer into early embryos is a powerful methodology for unraveling the molecular bases of developmental processes. One can attempt to minimize widespread effects of an exogenous gene by using tissue- or region-specific promoters in the few instances where they are available. We have developed a method that bypa
Retinal calcifications in cytomegalovirus retinitis.: Retina. 1993;13(1):46-9. Unique Identifier : AIDSLINE MED/93212164; Faber DW; Crapotta JA; Wiley CA; Freeman WR; Department of Opthalmology, University of California, San Diego.; Cytomegalovirus ( CMV ) retinitis has been well documented in the literature, both in patients with acquired immune deficiency syndrome (AIDS) and in other immunocompromised hosts. The clinical and histopathologic findings in three patients with AIDS and CMV retin
Generation and pathogenicity of an NB-tropic SL3-3 murine leukemia virus.: Virology. 1993 Apr;193(2):1013-7. Unique Identifier : AIDSLINE MED/93212480; Thomas CY; Nuckols JD; Murphy C; Innes D; Department of Internal Medicine, Microbiology, University of; Virginia Health Sciences Center, Charlottesville 22908.; A 428-base pair region of the gag gene of a molecular clone of the SL3-3 murine leukemia virus (MuLV) was replaced with allelic sequences that contain the NB-tropic determinants of the Moloney MuLV. SL3-3NB, the ecotropic virus derived from this modified clone, rapidly induced T-cell lymphoblastic lymphomas in the Fv-
Bovine leukemia virus: purification and characterization of the aspartic protease.: Virology. 1993 Apr;193(2):680-9. Unique Identifier : AIDSLINE MED/93212500; Menard A; Mamoun RZ; Geoffre S; Castroviejo M; Raymond S; Precigoux G; Hospital M; Guillemain B; Unite INSERM 328, Universite de Bordeaux II, Structures et; Fonctions des Retrovirus Humains, fondation Bergonie, France.; To develop efficient bovine leukemia virus (BLV) protease (PR) inhibitors, pure enzyme is required. For this, we have developed a two-step chromatographic nondenaturing purification protocol of PR from virions. As expected, the purified protein presents a molecular weight (14 kDa) and a NH2 terminal end fitting with p
Ocular examination and diagnosis in patients with the acquired immunodeficiency syndrome.: West J Med. 1993 Mar;158(3):254-62. Unique Identifier : AIDSLINE MED/93212556; Gariano RF; Rickman LS; Freeman WR; Department of Ophthalmology, Shiley Eye Center, La Jolla, CA; 92093.; Ocular involvement is seen frequently and is an important source of morbidity in patients with the acquired immunodeficiency syndrome. We outline here the general skills of physical diagnosis valuable to primary care physicians or infectious diseases specialists in recognizing and evaluating ocular complaints in patie
The HIV-1 tat protein enhances E2-dependent human papillomavirus 16 transcription.: Virus Res. 1993 Feb;27(2):133-45. Unique Identifier : AIDSLINE MED/93212588; Vernon SD; Hart CE; Reeves WC; Icenogle JP; Division of Viral and Rickettsial Diseases, Centers for Disease; Control, Atlanta, GA 30333.; Epidemiologic studies show an association between infection with human immunodeficiency virus type 1 (HIV-1) and human papillomavirus (HPV) associated anogenital disease. To investigate possible molecular mechanisms of HIV-1 modulation of HPV expression, we studied the effect of an HIV-1 regulatory protein, tat1, on g
Emancipate CDC [editorial]: Am J Public Health. 1993 Apr;83(4):491-2. Unique Identifier : AIDSLINE MED/93212855; Susser M
AIDS trends among Hispanics in the United States.: Am J Public Health. 1993 Apr;83(4):504-9. Unique Identifier : AIDSLINE MED/93212861; Diaz T; Buehler JW; Castro KG; Ward JW; Division of HIV/AIDS, Centers for Disease Control and Prevention,; Atlanta, Ga. 30345.; OBJECTIVES. In 1991 the incidence of acquired immunodeficiency syndrome (AIDS) in the United States was 31.6 per 100,000 population among Hispanics and 11.8 per 100,000 among non-Hispanic Whites. The purpose of this study was to further describe the AIDS epidemic among Hispanics by exa
Studies on the substrate specificity of the proteinase of equine infectious anemia virus using oligopeptide substrates.: Biochemistry. 1993 Apr 6;32(13):3347-53. Unique Identifier : AIDSLINE MED/93213803; Tozser J; Friedman D; Weber IT; Blaha I; Oroszlan S; Laboratory of Molecular Virology and Carcinogenesis, National; Cancer Institute-Frederick Cancer Research and Development; Center, Maryland 21702-1201.; The proteinase of the equine infectious anemia virus (EIAV), a lentivirus closely related to human immunodeficiency virus (HIV), was purified from concentrated virus. The specificity of the enzyme was characterized using oligopeptides representing naturally occurring cleavage sites in the Gag and Gag-Pol polyproteins.
Molecular model of equine infectious anemia virus proteinase and kinetic measurements for peptide substrates with single amino acid substitutions.: Biochemistry. 1993 Apr 6;32(13):3354-62. Unique Identifier : AIDSLINE MED/93213804; Weber IT; Tozser J; Wu J; Friedman D; Oroszlan S; Department of Pharmacology, Jefferson Cancer Institute, Thomas; Jefferson University, Philadelphia, Pennsylvania 19107.; A molecular model has been built of the equine infectious anemia virus (EIAV) proteinase on the basis of the crystal structures of the related Rous sarcoma virus (RSV) and human immunodeficiency virus (HIV) proteinases. The 104 residue long EIAV proteinase has 30 identical and 11 similar amino acids compared to those
[Infection by HIV and the hepatitis B, C, and D viruses in intravenous drug addicts. Seroprevalence at 1 year and its follow-up]: Enferm Infecc Microbiol Clin. 1993 Jan;11(1):8-13. Unique Identifier : AIDSLINE MED/93213905; Delgado-Iribarren A; Wilhelmi I; Padilla B; Canedo T; Gomez J; Elviro J; Servicio de Microbiologia, Hospital Severo Ochoa, Leganes,; Madrid.; BACKGROUND: The aim of the present article was to study the serology of intravenous drug user patients against the hepatitis B, C, D, and HIV, during 1990 and the follow-up during the same year, and 1991. METHODS: A study of 265 patients (mean age: 25 years, range: 16-45; 206 males and 59 females) was carried out. For
Protection against bovine leukemia virus infection by use of inactivated vaccines in cattle.: J Vet Med Sci. 1993 Feb;55(1):99-106. Unique Identifier : AIDSLINE MED/93213977; Fukuyama S; Kodama K; Hirahara T; Nakajima N; Takamura K; Sasaki O; Imanishi J; Division of Veterinary Microbiology, Kyoto Biken Laboratories,; Uji, Japan.; The protective effects of vaccines made from the viral materials of LK15 cell line (LK15 vaccine) or bat lung cell line (Bat2cl1; Bat vaccine) infected with bovine leukemia virus (BLV) were examined in cattle. Twelve cattle were vaccinated twice at 4-week interval then challenged 4 weeks after the second inoculation.
Small cell carcinoma of the anus in a human HIV carrier: report of a case.: Surg Today. 1993;23(1):85-8. Unique Identifier : AIDSLINE MED/93214258; Nakahara H; Moriya Y; Shinkai T; Hirota T; Department of Surgery, National Cancer Center Hospital, Tokyo,; Japan.; We report herein a rare case of metastatic anal small cell neuroendocrine carcinoma in a human immunodeficiency virus (HIV) carrier. This is only the third case of an HIV infection associated with the rare anorectal small cell carcinoma to be reported in the world literature. Although radiation and abdominoperineal re
Coupons attract high-risk untreated heroin users into detoxification.: Drug Alcohol Depend. 1993 Feb;31(3):247-52. Unique Identifier : AIDSLINE MED/93215450; Sorensen JL; Costantini MF; Wall TL; Gibson DR; University of California, San Francisco.; This study examined the degree that the distribution of coupons brought drug users at risk of HIV infection into outpatient detoxification treatment. Demographic characteristics and outcome indicators were compared for patients recruited through coupon redemption (n = 238) versus other referral channels (n = 1129). Si
Neutralizing antibody to vesicular stomatitis virus (HTLV-I) pseudotype in infants born to seropositive mothers.: Jpn J Cancer Res. 1993 Feb;84(2):114-6. Unique Identifier : AIDSLINE MED/93216502; Iwahara Y; Sawada T; Taguchi H; Hoshino H; Umemoto M; Take H; Foung S; Miyoshi I; Department of Medicine, Kochi Medical School.; Breast feeding is the major route of mother-to-child transmission of human T-cell leukemia virus type I (HTLV-I). Our experiments with rabbits have shown that passive immunization is capable of blocking cell-to-cell infection of HTLV-I by blood transfusion or breast feeding. In this study, sera were collected serially
Development of a recombinant bovine leukemia virus vector for delivery of a synthetic bovine growth hormone-releasing factor gene into bovine cells.: J Anim Sci. 1993 Mar;71(3):687-93. Unique Identifier : AIDSLINE MED/93216538; Mehigh CS; Elias VD; Mehigh RJ; Helferich WG; Tucker HA; Department of Animal Science, Michigan State University, East; Lansing 48824.; Continuous intravenous infusion of bovine growth hormone-releasing factor (bGRF) increases milk synthesis in dairy cattle by as much as 46%. We have begun to develop a system for delivery and expression of a synthetic bGRF gene in cultured bovine cells using the provirus of the bovine leukemia virus (BLV). The gene en
Evaluation of an enzyme-linked immunosorbent assay for detection of antibodies to bovine leukemia virus in serum and milk.: J Clin Microbiol. 1993 Apr;31(4):979-81. Unique Identifier : AIDSLINE MED/93216934; Nguyen VK; Maes RF; Anda Biologicals, Strasbourg, France.; The results of examination of 375 bovine serum and 150 bovine milk samples for detection of bovine leukemia virus infection by the immunodiffusion technique were compared with those of an enzyme-linked immunosorbent assay (ELISA). It was concluded that the ELISA is another useful method for the detection of antibodies
Synthesis and anti-HIV evaluation of D4T and D4T 5'-monophosphate prodrugs.: J Med Chem. 1993 Apr 2;36(7):826-30. Unique Identifier : AIDSLINE MED/93217952; Sergheraert C; Pierlot C; Tartar A; Henin Y; Lemaitre M; Faculte de Pharmacie, Institut Pasteur de Lille, URA CNRS 1309,; Lille, France.; Several 5-monophosphate D4T derivatives and their analogues were synthesized as potential lipophilic prodrugs of D4T. Cholesteryl D4T phosphate diester and bis-5 -D4T phosphate inhibited HIV replication in CEM-Cl13 cells more efficiently than D4T itself as measured by the inhibition of cytopathic effect based on MTT a
[Molecular genotypes of hepatitis C virus and their divergence times]: Nippon Rinsho. 1993 Feb;51(2):304-11. Unique Identifier : AIDSLINE MED/93218087; Mizokami M; Ohba K; Second Department of Internal Medicine, Nagoya City University; Medical School.; We collected the nucleotide sequences of hepatitis C virus (HCV) from the international DNA data base DDBJ/EMBL/GenBank to carry out molecular evolutionary analysis of HCVs. Using these sequences, we constructed the phylogenetic trees for the 5 non-coding, Core, Env., E2/NS1, NS3, NS4 and NS5 regions of HCV. The numb
A rational biologic basis for safe sexual conduct in preventing the spread of AIDS.: Lymphology. 1993 Mar;26(1):1-3. Unique Identifier : AIDSLINE MED/93218256; Shields JW; Department of Medicine and Hematology, Santa Barbara Medical; Foundation Clinic, California.
Oral manifestations of cytomegalovirus infection.: Oral Surg Oral Med Oral Pathol. 1993 Apr;75(4):443-51. Unique Identifier : AIDSLINE MED/93218944; Epstein JB; Sherlock CH; Wolber RA; Department of Dentistry British Columbia Cancer Agency,; Vancouver, Canada.; Disease caused by cytomegalovirus is reported with increasing frequency. Cytomegalovirus is an important pathogen in immunocompromised and immunosuppressed patients. The most common manifestation of cytomegalovirus infection of the gastrointestinal tract including the oral mucosa i
Concurrent oral cytomegalovirus and herpes simplex virus infection in association with HIV infection. A case report.: Oral Surg Oral Med Oral Pathol. 1993 Apr;75(4):488-94. Unique Identifier : AIDSLINE MED/93218952; Heinic GS; Northfelt DW; Greenspan JS; MacPhail LA; Greenspan D; Department of Stomatology and Oral AIDS Center, University of; California, San Francisco.; Recurrent oral herpes simplex virus lesions are common in both immunocompetent and immunocompromised persons. In contrast, cytomegalovirus-associated intraoral lesions are rarely seen, even in the immunocompromised host. We report a case of concurrent oral herpes simplex virus and cytomegalovirus infection, appearing
HIV, otolaryngologists, and government regulation [editorial]: Otolaryngol Head Neck Surg. 1993 Mar;108(3):209-12. Unique Identifier : AIDSLINE MED/93218972; Osguthorpe JD
CDC recruits business, labor in fight against AIDS [news]: Public Health Rep. 1993 Mar-Apr;108(2):259-60. Unique Identifier : AIDSLINE MED/93219522
A comparison of clinical features in tuberculosis associated with infection with human immunodeficiency viruses 1 and 2.: Trans R Soc Trop Med Hyg. 1993 Jan-Feb;87(1):57-9. Unique Identifier : AIDSLINE MED/93220115; Gnaore E; Sassan-Morokro M; Kassim S; Ackah A; Yesso G; Adjorlolo G; Digbeu H; Coulibaly D; Coulibaly IM; Doorly R; et al; Project RETRO-CI, Abidjan, Cote d'Ivoire.; Between July 1989 and December 1990, 4504 new adult patients with tuberculosis were screened for antibodies to human immunodeficiency viruses (HIV) 1 and 2 in Abidjan s 2 tuberculosis treatment centres. The prevalence levels of HIV-1 and HIV-2 infections were 30.2% and 4.2% respectively, a further 9.3% of patients rea
Shedding of bovine leukosis virus in nasal secretions of infected animals.: Vet Rec. 1993 Mar 13;132(11):276-8. Unique Identifier : AIDSLINE MED/93220236; Lucas MH; Roberts DH; Banks J; Central Veterinary Laboratory, New Haw, Addlestone, Surrey.
Morphological characteristics of malignant T-cell lymphomas in baboons.: Virchows Arch A Pathol Anat Histopathol. 1993;422(2):109-20. Unique Identifier : AIDSLINE MED/93220246; Yakovleva LA; Lennert K; Chikobava MG; Indzhiia LV; Klotz IN; Lapin BA; Institute of Experimental Pathology and Therapy, Sukhumi,; Abkhazia, Georgia.; Fifteen cases of generalized peripheral T-cell non-Hodgkin s lymphoma in baboons were phenotyped immunologically and morphologically. Using the updated Kiel classification the cases included low-grade and high-grade lymphomas and low-grade lymphomas that had transformed into high-g
Projections for HIV infection and AIDS [news]: Am Fam Physician. 1993 Apr;47(5):1298. Unique Identifier : AIDSLINE MED/93220567
Experimental AIDS drug, d4T, now available to patients in critical need [news]: Ann Allergy. 1993 Apr;70(4):A19. Unique Identifier : AIDSLINE MED/93220976
Cytomegalovirus myelitis in perinatally acquired HIV.: Arch Dis Child. 1993 Mar;68(3):399-401. Unique Identifier : AIDSLINE MED/93221186; Gungor T; Funk M; Linde R; Jacobi G; Horn M; Kreuz W; Centre of Paediatrics, Johann Wolfgang Goethe University; Hospital, 6000 Frankfurt/Main, Germany.; A 7 year old child perinatally infected with HIV who died from progressive muscular paralysis and central nervous respiratory failure is described. Cytomegalovirus ( CMV ) prophylaxis with a special intravenous CMV hyper-immunoglobulin had been successfully conduc
Predominance of Epstein-Barr virus DNA in immature CD21-deficient B-lymphocytes from HIV-infected patients [letter]: AIDS. 1993 Feb;7(2):292-3. Unique Identifier : AIDSLINE MED/93221744; Benedetto A; Camporiondo MP; Di Caro A; Gallone D; Garbuglia AR; Sette P; Zaniratti MS
Needlesticks, infection control and nurse liability.: Natl Med Leg J. 1993 2nd Quarter;4(2):1, 6-7. Unique Identifier : AIDSLINE MED/93222378; Jenner RK; Bourke MK
Toxoplasma gondii: induction of toxoplasmic encephalitis in mice with chronic infection by inoculation of a murine leukemia virus inducing immunodeficiency.: Exp Parasitol. 1993 Feb;76(1):39-45. Unique Identifier : AIDSLINE MED/93223826; Watanabe H; Suzuki Y; Makino M; Fujiwara M; Department of Immunology, Niigata University School of Medicine,; Japan.; Infection with the avirulent Fukaya strain of Toxoplasma gondii induced few inflammatory responses in the brain of C57BL/6 mice. When mice with chronic infection with the Fukaya strain were challenged with murine leukemia virus (MuLV) LP-BM5, which is known to induce a remarkable immunodeficiency in mice, those mice s
[Infectious non lithiasic cholangitis and cholecystitis]: Gastroenterol Clin Biol. 1993;17(1):44-52. Unique Identifier : AIDSLINE MED/93223964; Roulot D; Coste T; Service d'Hepato-Gastroenterologie, Hopital Avicenne, Bobigny.
Dose response and timing effects in the therapy of the LP-BM5 murine retrovirus-induced lymphoproliferative immunodeficiency disease with diethyldithiocarbamate.: Int J Immunopharmacol. 1993 Feb;15(2):137-43. Unique Identifier : AIDSLINE MED/93224222; Hersh EM; Funk CY; Petersen EA; Ryschon KL; Mosier DE; Section of Hematology, University of Arizona College of Medicine,; Tucson 85724.; Diethyldithiocarbamate (DTC) was used to treat the murine, retrovirus-induced, immunodeficiency disease (MAIDS). Once-weekly treatment was not effective and 800 mg/kg was toxic. When 200, 400 and 600 mg/kg were given i.p., 5 days per week, starting either on the day of virus inoculation or 14 days later, a dose-respon
The GGTCA palindrome and cognate cellular factors in trans-regulation of human immunodeficiency virus long terminal repeat by herpes simplex virus.: J Gen Virol. 1993 Apr;74 ( Pt 4):715-23. Unique Identifier : AIDSLINE MED/93224893; Feng CP; Kulka M; Aurelian L; Department of Pharmacology and Experimental Therapeutics,; University of Maryland, School of Medicine, Baltimore 21201.; Molecular interactions between herpes simplex virus type 1 (HSV-1) and human immunodeficiency virus (HIV) were investigated in the promonocytic cell line U937. HSV-1-mediated activation was observed in transient expression assays with hybrid constructions containing the HIV long terminal repeat (LTR)-directed chloramp
From the Centers for Disease Control and Prevention. Recommendations for HIV testing services for inpatients and outpatients in acute-care hospital settings.: JAMA. 1993 Apr 28;269(16):2071-2. Unique Identifier : AIDSLINE MED/93225180
From the Centers for Disease Control and Prevention. Technical guidance on HIV counseling.: JAMA. 1993 Apr 28;269(16):2072-6. Unique Identifier : AIDSLINE MED/93225181
[Diagnostic criteria for AIDS (letter)]: Sangre (Barc). 1993 Feb;38(1):67. Unique Identifier : AIDSLINE MED/93227137; Diaz Manglano J
Foscarnet treatment of cytomegalovirus gastrointestinal infections in acquired immunodeficiency syndrome patients who have failed ganciclovir induction.: Am J Gastroenterol. 1993 Apr;88(4):542-8. Unique Identifier : AIDSLINE MED/93228027; Dieterich DT; Poles MA; Dicker M; Tepper R; Lew E; New York University Medical Center, NY.; This compassionate-use study examined the efficacy of foscarnet in patients with AIDS and cytomegalovirus ( CMV ) gastrointestinal disease who had failed ganciclovir induction. Nineteen male homosexuals with AIDS and biopsy-pro
Compatibility of Tat and Rev transactivators in the primate lentiviruses.: Arch Virol. 1993;129(1-4):1-10. Unique Identifier : AIDSLINE MED/93228433; Sakai H; Sakuragi J; Sakuragi S; Kawamura M; Adachi A; Institute for Virus Research, Kyoto University, Japan.; Primate immunodeficiency viruses carry a unique set of transacting regulator genes, which are essential for viral replication. The exchangeability of these Tat and Rev transactivators derived from viruses of the four major subgroups identified to date was assessed in transient transfection and infection assay systems.
Effects of immunization with the p12 proteins of LP-BM5 defective and ecotropic viruses on development of MAIDS.: Arch Virol. 1993;129(1-4):155-66. Unique Identifier : AIDSLINE MED/93228439; Tang Y; Hugin AW; Hartley JW; Fredrickson TN; Morse HC 3d; Chattopadhyay SK; Laboratory of Immunopathology, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda,; Maryland.; Among murine leukemia viruses (MuLV) present in the LP-BM5 virus mixture, the agent etiologic for an acquired immunodeficiency syndrome (MAIDS) is replication defective, containing only a single open reading frame which includes all of gag. The Gag polyprotein encoded by the defective virus, termed BM5def, differs mos
Affinity of the antiviral enantiomers of oxathiolane cytosine nucleosides for human 2'-deoxycytidine kinase.: Biochem Pharmacol. 1993 Apr 6;45(7):1540-3. Unique Identifier : AIDSLINE MED/93228673; Shewach DS; Liotta DC; Schinazi RF; Department of Pharmacology, University of Michigan, Ann Arbor; 48109.; The two enantiomers of 2 ,3 -dideoxy-3 -thiacytidine (BCH-189) and their 5-fluoro analogs (FTC) were found to be good substrates for human 2 -deoxycytidine kinase with Km values in the 5.7 to 42.1 microM range. The affinity of the (-)-enantiomers was greater than that of the (+)-compounds. These results may explain th
Pharmacokinetics of 2-fluorodideoxycytidine (2FddC) in patients infected with human immunodeficiency virus.: Br J Clin Pharmacol. 1993 Mar;35(3):255-60. Unique Identifier : AIDSLINE MED/93229216; Williams PE; Muirhead GJ; Sereni D; Rousseau FS; Edelman K; Hooker M; Pharmacokinetics and Metabolism Department, Roche Products Ltd,; Hertfordshire, England.; 1. The aim of this study was to estimate an oral dosage regimen of 2FddC giving peak plasma drug concentrations close to the antiretroviral IC50 of 150 ng ml-1. 2. A total of 55 doses (40 intravenous infusions and 15 oral solutions) were given to 21 patients. One group (n = 6-11) received single doses of 0.01 mg kg-1
Epstein-Barr virus-associated non-Hodgkin's lymphoma in patients infected with the human immunodeficiency virus [see comments]: Blood. 1993 Apr 15;81(8):2102-9. Unique Identifier : AIDSLINE MED/93229750; Shibata D; Weiss LM; Hernandez AM; Nathwani BN; Bernstein L; Levine AM; Department of Pathology, Los Angeles County University of; Southern California Medical Center 90033.; Lymphoproliferations associated with Epstein-Barr virus (EBV) commonly arise in settings of immune dysfunction, including human immunodeficiency virus (HIV) infection. In this study, EBV was associated with 39 of 59 (66%) HIV-related systemic lymphomas. Unlike the lymphoproliferations that arise in the setting of tran
Non-radioactive ribotyping of Haemophilus ducreyi using a digoxigenin labelled cDNA probe.: Epidemiol Infect. 1993 Apr;110(2):289-95. Unique Identifier : AIDSLINE MED/93231243; Brown TJ; Ison CA; Department of Medical Microbiology, St Mary's Hospital Medical; School, Paddington, London.; Haemophilus ducreyi, the causal organism of chancroid, has increased in significance recently due to its association with HIV transmission. Most previous typing systems have exploited phenotypic characteristics. Detection of ribosomal RNA cistrons, ribotyping, was successfully developed to examine H. ducreyi, but requ
Cytomegalovirus infection presenting as acute periodontal infection in a patient infected with the human immunodeficiency virus.: J Clin Periodontol. 1993 Apr;20(4):282-5. Unique Identifier : AIDSLINE MED/93232334; Dodd CL; Winkler JR; Heinic GS; Daniels TE; Yee K; Greenspan D; Oral AIDS Center, Department of Stomatology, University of; California, San Francisco.; During childhood, many people acquire primary infection with cytomegalovirus ( CMV ), one of the herpes viruses. If they later become immunosuppressed, such as occurs with human immunodeficiency virus (HIV) infection, CMV is li
Cryptococcosis in an AIDS patient: itraconazole efficacy after other therapeutic failures [letter]: J Infect. 1993 Mar;26(2):221-2. Unique Identifier : AIDSLINE MED/93232642; Pelloux H; Lebeau B; Manquat G; Leclercq P; Blanc M; Ambroise-Thomas P; Grillot R
Apoptosis induced by tumor necrosis factor in cells chronically infected with feline immunodeficiency virus.: J Virol. 1993 May;67(5):2429-33. Unique Identifier : AIDSLINE MED/93233204; Ohno K; Nakano T; Matsumoto Y; Watari T; Goitsuka R; Nakayama H; Tsujimoto H; Hasegawa A; Department of Veterinary Internal Medicine, Faculty of; Agriculture, University of Tokyo, Japan.; Tumor necrosis factor alpha (TNF-alpha) induced morphologic changes such as chromatin condensation and cell shrinkage in a feline fibroblastic cell line (CRFK) chronically infected with feline immunodeficiency virus (FIV) but not in uninfected CRFK cells. DNA extracted from TNF-alpha-treated CRFK cells infected with F
Murine retrovirus-induced spongiform encephalopathy: disease expression is dependent on postnatal development of the central nervous system.: J Virol. 1993 May;67(5):2601-10. Unique Identifier : AIDSLINE MED/93233225; Lynch WP; Portis JL; Rocky Mountain Laboratories, National Institute of Allergy and; Infectious Diseases, Hamilton, Montana 59840.; In this report, we have examined the role of central nervous system (CNS) development in the pathogenesis of neurodegenerative disease induced by murine retroviruses. This was accomplished by comparing the effect of delivering viruses, with either severe or marginal neurovirulence (J. L. Portis, S. Czub, C. F. Garon,
Epstein-Barr virus nuclear antigen 2 transactivates the long terminal repeat of human immunodeficiency virus type 1.: J Virol. 1993 May;67(5):2853-61. Unique Identifier : AIDSLINE MED/93233254; Scala G; Quinto I; Ruocco MR; Mallardo M; Ambrosino C; Squitieri B; Tassone P; Venuta S; Dipartimento di Biochimica e Biotecnologie Mediche, Universita; Federico II, Naples, Italy.; Human immunodeficiency virus type 1 (HIV-1)-infected subjects show a high incidence of Epstein-Barr virus (EBV) infection. This suggests that EBV may function as a cofactor that affects HIV-1 activation and may play a major role in the progression of AIDS. To test this hypothesis, we generated two EBV-negative human B
Rifabutin.: Med Lett Drugs Ther. 1993 Apr 30;35(895):36-8. Unique Identifier : AIDSLINE MED/93233551
Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding.: Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3428-32. Unique Identifier : AIDSLINE MED/93234510; Bushman FD; Engelman A; Palmer I; Wingfield P; Craigie R; Laboratory of Molecular Biology, National Institute of Diabetes; and Digestive and Kidney Diseases, National Institutes of Health,; Bethesda, MD 20892.; The integrase protein of human immunodeficiency virus type 1 carries out a set of polynucleotidyl transfer reactions that result in the covalent attachment of the retroviral cDNA to host DNA. We have analyzed the activities of a set of deletion derivatives of the integrase protein. The analysis reveals that a central
Effect of bovine immunodeficiency-like virus infection on immune function in experimentally infected cattle.: Vet Immunol Immunopathol. 1993 Mar;36(2):91-105. Unique Identifier : AIDSLINE MED/93235434; Flaming K; van der Maaten M; Whetstone C; Carpenter S; Frank D; Roth J; Department of Microbiology, Immunology, and Preventive Medicine,; Iowa State University, Ames 50011.; Bovine immunodeficiency-like virus (BIV) is a bovine lentivirus that has antigenic and genetic homology with the human immunodeficiency virus. Little work has been reported on the effect of BIV infection on bovine immune function. This study was designed to evaluate lymphocyte blastogenesis, mononuclear cell subset nu
[Contribution of nuclear medicine to management of pulmonary complications in patients with acquired immune deficiency (published erratum appears in Acta Med Austriaca 1993;20(3):69)]: Acta Med Austriaca. 1993;20(1-2):36-41. Unique Identifier : AIDSLINE MED/93235522; Kohn H; Armbruster C; Konig B; Vetter N; Mostbeck A; Institut fur Nuklearmedizin, Wilhelminenspital, Wien.; Opportunistic lung infections and malignancies are life-threatening complications in HIV-positive patients. In 72 HIV-positive patients the role of different non-invasive tests such as lung function tests, blood gas analysis, 67 gallium scanning and epithelial lung clearance with 99m Tc-DTPA for the management of thes
[Ocular manifestations in human immunodeficiency virus seropositive patients]: Nippon Ganka Gakkai Zasshi. 1993 Feb;97(2):253-9. Unique Identifier : AIDSLINE MED/93235757; Nagata Y; Matsumoto S; Fujino Y; Nishi M; Nakashima S; Mochizuki M; Oka S; Kimura S; Mitamura K; Shimada K; Eye Clinic, Self Defense Forces Central Hospital, Setagaya,; Japan.; Ocular manifestations in 56 human immunodeficiency virus (HIV) seropositive patients were examined prospectively. Eighteen of them had acquired immunodeficiency syndrome (AIDS), 14 had AIDS-related complex (ARC), and 30 were asymptomatic carriers (AC). Two AIDS patients progressed from ARC and four ARC patients from A
Foscarnet in the treatment of cytomegalovirus esophagitis [letter; comment]: Am J Med. 1993 Apr;94(4):446-7. Unique Identifier : AIDSLINE MED/93235874; Nelson MR; Hawkins DA; Gazzard BG
Human foamy virus proteins accumulate in neurons and induce multinucleated giant cells in the brain of transgenic mice [published erratum appears in Am J Pathol 1993 Aug;143(2):648]: Am J Pathol. 1993 Apr;142(4):1061-71. Unique Identifier : AIDSLINE MED/93235935; Aguzzi A; Wagner EF; Netzer KO; Bothe K; Anhauser I; Rethwilm A; Institute of Molecular Pathology, Vienna, Austria.; Human foamy virus (HFV) is a retrovirus encoding structural genes and, like human immunodeficiency virus and human T cell leukemia virus I, several ancillary reading frames collectively termed the be1 genes. We have previously shown that HFV transgenic mice develop an encephalopathy with neuronal loss in hippocampus a
High prevalence of Epstein-Barr virus in the Reed-Sternberg cells of HIV-associated Hodgkin's disease.: Am J Pathol. 1993 Apr;142(4):1073-9. Unique Identifier : AIDSLINE MED/93235936; Herndier BG; Sanchez HC; Chang KL; Chen YY; Weiss LM; Department of Pathology, San Francisco General Hospital, CA; 94110.; The Epstein-Barr virus (EBV) has been implicated in the pathogenesis of Hodgkin s disease, with an frequency of 15 to 50% in the immunocompetent host. We studied 12 formalin-fixed, paraffin-embedded cases of Hodgkin s disease occurring in human immunodeficiency virus-infected individuals to determine the frequency of
[Viral risks associated with blood transfusion]: Rev Fr Transfus Hemobiol. 1993 Jan;36(1):73-81. Unique Identifier : AIDSLINE MED/93236666; Barin F; Laboratoire de Virologie, URA CNRS 1334, CHRU Bretonneau et UFR; Sciences Pharmaceutiques, Tours.; The presence of viruses in blood cells or plasma from asymptomatic donors is the major risk of transmitting an infectious agent through blood transfusion. The main viruses involved are hepatitis viruses and retroviruses. The risk of transmitting hepatitis B virus (HBV) and hepatitis C virus (HCV) has been progressivel
Epstein-Barr virus and carcinomas.: Int J Clin Lab Res. 1993;23(1):17-24. Unique Identifier : AIDSLINE MED/93237538; Niedobitek G; Herbst H; Young LS; Department of Pathology, University of Birmingham, UK.; The Epstein-Barr virus, a human B lymphotropic herpes virus, is strongly associated with undifferentiated nasopharyngeal carcinoma, which is endemic in Southern China and North Africa. More recently, an association of the virus with certain other epithelial malignancies has been des
Cytogenetic rearrangement of C-MYC oncogene occurs prior to infection with Epstein-Barr virus in the monoclonal malignant B cells from an AIDS patient.: Leuk Lymphoma. 1993 Jan;9(1-2):157-64. Unique Identifier : AIDSLINE MED/93237805; Roncella S; Di Celle PF; Cutrona G; Carbone A; Sessarego M; Landonio G; Foa R; Rowe M; Ferrarini M; Istituto Nazionale per la Ricerca sul Cancro, IST, Laboratorio di; Immunologia Clinica, Genova, Italy.; Two cell lines were originated from the peripheral blood (PB-LAM) and bone-marrow (BM-LAM) of a patient with Burkitt-type acute lymphoblastic leukemia and AIDS. 26 and 7 clones were isolated from PB-LAM and BM-LAM respectively by limiting dilution. All of these had surface IgM lambda and the CD10 marker with low to ab
Synthesis and antiviral activity of carbocyclic oxetanocin analogues (C-OXT-A, C-OXT-G) and related compounds. II.: Chem Pharm Bull (Tokyo). 1993 Mar;41(3):516-21. Unique Identifier : AIDSLINE MED/93238344; Maruyama T; Hanai Y; Sato Y; Snoeck R; Andrei G; Hosoya M; Balzarini J; De Clercq E; Department of Pharmaceutical Sciences, Tokushima Bunri; University, Japan.; 9-(cis-3-Hydroxymethyl-2-methylenecyclobutyl)guanine (3b) and 9-(3-methylene-trans-2-hydroxymethylcyclobutyl)guanine (4b) were prepared from N2-isobutyryl-9-[trans-trans-2,3-bis(hydroxymethyl)cyclobutyl]gua- nine (2f) or 2,3-bis(hydroxymethyl)-1-cyclobutanol (7b). Carbocyclic oxetanocin analogues (A, 1d; G, 2d) and re
High incidence of monoclonal EBV episomes in Hodgkin's disease and anaplastic large-cell KI-1-positive lymphomas in HIV-1-positive patients.: Int J Cancer. 1993 Apr 22;54(1):53-9. Unique Identifier : AIDSLINE MED/93239382; Boiocchi M; De Re V; Gloghini A; Vaccher E; Dolcetti R; Marzotto A; Bertola G; Carbone A; Division of Experimental Oncology, Istituto di Ricovero e Cura a; Carattere Scientifico, Aviano PN, Italy.; A series of selected lymphoid malignancies (LMs) occurring in Italian HIV-1-infected (HIV+) patients, principally intravenous drug users, was investigated. In addition to small non-cleaved-cell (SNCC) and large-cell immunoblastic (LCI) non-Hodgkin s lymphomas (NHLs), a relatively high occurrence of anaplastic large-ce
CDC grants 'equivalency' to 22 state guidelines for management of HIV- and HBV-infected healthcare workers [news]: Infect Control Hosp Epidemiol. 1993 Mar;14(3):154. Unique Identifier : AIDSLINE MED/93239974; Pugliese G
AIDS & HIV: the dilemma of the health care worker.: J Neurosci Nurs. 1993 Apr;25(2):118-24. Unique Identifier : AIDSLINE MED/93240017; Wicher CP
Characterization of a novel Hodgkin cell line, HD-MyZ, with myelomonocytic features mimicking Hodgkin's disease in severe combined immunodeficient mice.: J Exp Med. 1993 May 1;177(5):1257-68. Unique Identifier : AIDSLINE MED/93240107; Bargou RC; Mapara MY; Zugck C; Daniel PT; Pawlita M; Dohner H; Dorken B; Max Delbruck Center for Molecular Medicine, Berlin-Buch,; Germany.; A novel Hodgkin cell line, designated HD-MyZ, was established from the pleural effusion of a 29-yr-old patient with Hodgkin s disease (HD) of nodular sclerosing type. The majority of cells grow adherently and display typical morphological characteristics of Reed-Sternberg (RS) and Hodgkin (H) cells, i.e., large multi-
Cytomegalovirus ventriculoencephalitis in AIDS. A syndrome with distinct clinical and pathologic features.: Medicine (Baltimore). 1993 Mar;72(2):67-77. Unique Identifier : AIDSLINE MED/93241029; Kalayjian RC; Cohen ML; Bonomo RA; Flanigan TP; Department of Medicine, University Hospitals of Cleveland, Ohio.; Cytomegalovirus ventriculoencephalitis is a late and terminal complication of AIDS. Cytomegalovirus retinitis was diagnosed before the onset of encephalitis in all but 1 of the 7 patients in this series. A distinct clinical presentation was observed, with encephalitis often associated with cranial nerve deficits and g
Cyclic AMP regulation of the human choline acetyltransferase gene.: Neurochem Res. 1993 Mar;18(3):271-5. Unique Identifier : AIDSLINE MED/93241456; Li YP; Baetge EE; Hersh LB; Department of Biochemistry, University of Texas Southwestern; Medical Center, Dallas 79235.; Regulation of the human choline acetyltransferase gene by 8-bromo-cAMP was investigated by transfecting into NS-20Y cells choline acetyltransferase promoter sequences fused to the reporter gene firefly luciferase. Promoter activity was localized to nucleotides -163 to +73. This region of the gene responded to 8-bromo-
[Opportunistic infections in AIDS. The pulmonary manifestations]: Radiol Med (Torino). 1993 Jan-Feb;85(1-2):40-8. Unique Identifier : AIDSLINE MED/93242185; Scialpi M; Gius S; Branz F; Dalla Palma F; U.O. di Radiodiagnostica, USL C5 Centro S. Chiara, Largo Medaglie; d'Oro, Trento.; The initial and follow-up chest radiographs of 31 patients with the acquired immunodeficiency syndrome (AIDS) were reviewed to assess the spectrum and frequency of opportunistic pulmonary infections. In our series, the most common pulmonary infections seen on chest films were: Pneumocystis carinii pneumonia (PCP) (n =
FDA taps anti-emetic for treatment of AIDS complication [news]: RN. 1993 Apr;56(4):93. Unique Identifier : AIDSLINE MED/93242337
The diagnosis and epidemiology of feline immunodeficiency virus (FIV) infection in The Netherlands.: Tijdschr Diergeneeskd. 1993 Mar;118 Suppl 1:43S-44S. Unique Identifier : AIDSLINE MED/93242588; Egberink HF; Hendriks P; Slappendel RJ; Horzinek MC; Institute of Virology, Department of Infectious Diseases and; Immunology, Faculty of Veterinary Medicine, Utrecht University,; The Netherlands.
Analysis of retroviral assembly using a vaccinia/T7-polymerase complementation system.: Virology. 1993 May;194(1):192-9. Unique Identifier : AIDSLINE MED/93242746; Dong J; Hunter E; Department of Microbiology, University of Alabama, Birmingham; 35294.; The nature of protein-protein interactions during retroviral assembly is not well understood, and mutational analyses of the potential signals involved in the viral assembly process has been difficult, particularly with the avian retroviruses due to the level of viral proteins expressed in the clonal cell lines contai
Tubular aggregates and partial cytochrome c oxidase deficiency in skeletal muscle of patients with AIDS treated with zidovudine.: Acta Neuropathol (Berl). 1993;85(4):431-6. Unique Identifier : AIDSLINE MED/93243118; Chariot P; Benbrik E; Schaeffer A; Gherardi R; Service de Toxicologie, Hopital Henri Mondor, Creteil, France.; We report on two patients, who had myalgias while receiving long-term zidovudine treatment for an HIV infection, in whom muscle biopsy findings included a partial cytochrome c oxidase (CCO) deficiency, a feature of zidovudine myopathy, and tubular aggregates, a finding hitherto unreported in HIV-infected patients. The
Reversible cardiac dysfunction associated with foscarnet therapy for cytomegalovirus esophagitis in an AIDS patient.: Am Heart J. 1993 May;125(5 Pt 1):1439-41. Unique Identifier : AIDSLINE MED/93243224; Brown DL; Sather S; Cheitlin MD; Department of Medicine, San Francisco General Hospital, CA 94110.
Prevention and treatment of Pneumocystis pneumonia [letter; comment]: N Engl J Med. 1993 May 27;328(21):1569. Unique Identifier : AIDSLINE MED/93241275; Min DI; Noormohamed SE
Histopathology of human immunodeficiency virus-associated esophageal disease [see comments]: Am J Gastroenterol. 1993 Apr;88(4):549-51. Unique Identifier : AIDSLINE MED/93228028; Bonacini M; Young T; Laine L; Division of Gastrointestinal and Liver Diseases, University of; Southern California, School of Medicine, Los Angeles.; We evaluated the histopathologic features of the esophageal mucosa in 88 patients seropositive for human immunodeficiency virus (HIV). All patients had an upper endoscopy because of esophageal symptoms. Forceps biopsies and brushings of the esophagus were examined histologically and cytologically for evidence of viral
Structural features of two T-cell-specific genes that suggest a potential role in HTLV-I-associated pathology.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):105-7. Unique Identifier : AIDSLINE MED/93207814; Patarca R; Fletcher MA; Cantor H; E.M. Papper Laboratory of Clinical Immunology, University of; Miami School of Medicine, FL 33101.; The Rpt-1 gene product is an intranuclear protein expressed by CD4+ T-cells, which may regulate expression of the interleukin-2 receptor. Structural analysis of Rpt-1 reveals structural motifs that are shared by a group of transcriptional regulatory proteins with oncogenic potential. We suggest that altered expression
Cell-surface heparan sulfate proteoglycan mediates HIV-1 infection of T-cell lines.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):167-74. Unique Identifier : AIDSLINE MED/93207824; Patel M; Yanagishita M; Roderiquez G; Bou-Habib DC; Oravecz T; Hascall VC; Norcross MA; Division of Cytokine Biology, Food and Drug Administration,; Bethesda, MD 20892.; The role of cell-surface proteoglycans in human immunodeficiency virus (HIV) infection of T-cell lines was investigated. HIV-1-susceptible lymphoblastic T-cell lines, MT-4 and H9, were analyzed for proteoglycan synthesis and found to make heparan sulfate (HS) and chondroitin sulfate proteoglycans. Enzymatic treatment
Quantitation of unintegrated HIV-1 DNA in asymptomatic patients in the presence or absence of antiretroviral therapy.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):183-7. Unique Identifier : AIDSLINE MED/93207826; Bush CE; Donovan RM; Smereck SM; Strang D; Markowitz N; Saravolatz LD; Department of Internal Medicine, Henry Ford Hospital, Detroit, MI; 48202.; The objective of this work was to determine the amount of unintegrated human immunodeficiency virus (HIV) DNA (HIV uDNA) in asymptomatic individuals in the presence or absence of antiretroviral therapy. Twenty-one healthy seropositive individuals with no history of any opportunistic infection or previous use of nucleo
Dynamics of HIV infection of CD4+ T cells.: Math Biosci. 1993 Mar;114(1):81-125. Unique Identifier : AIDSLINE MED/93208399; Perelson AS; Kirschner DE; De Boer R; Theoretical Division, Los Alamos National Laboratory, New Mexico.; We examine a model for the interaction of HIV with CD4+ T cells that considers four populations: uninfected T cells, latently infected T cells, actively infected T cells, and free virus. Using this model we show that many of the puzzling quantitative features of HIV infection can be explained simply. We also consider
Murine HIV-1 p24 specific T lymphocyte activation by different antigen presenting cells: B lymphocytes from immunized mice present core protein to T cells.: Immunol Lett. 1993 Jan;35(1):45-50. Unique Identifier : AIDSLINE MED/93209676; Fyfe L; Maingay JP; Howie SE; Department of Pathology, Edinburgh University Medical School, UK.; Mice were injected with three doses of baculovirus-produced recombinant HIV-1 p24 core protein in alum adjuvant. CD4 positive T lymphocytes from immunized animals proliferated in vitro in the presence of antigen and peritoneal macrophages (Mps) or splenic dendritic cells (DCs) from non-immunized mice as antigen presen
Infective and anti-infective properties of breastmilk from HIV-1-infected women [see comments]: Lancet. 1993 Apr 10;341(8850):914-8. Unique Identifier : AIDSLINE MED/93211200; Van de Perre P; Simonon A; Hitimana DG; Dabis F; Msellati P; Mukamabano B; Butera JB; Van Goethem C; Karita E; Lepage P; National AIDS Control Programme, AIDS Reference Laboratory,; Kigali, Rwanda.; Human immunodeficiency virus type 1 (HIV-1) is transmitted mainly by cell-to-cell contact. We postulated that transmission of HIV-1 through breastmilk could be favoured by the presence of infected cells, by deficiency of anti-infective substances in breastmilk, or both factors. 215 HIV-1-infected women were enrolled a
Breast milk and HIV-1 transmission [comment]: Lancet. 1993 Apr 10;341(8850):930-1. Unique Identifier : AIDSLINE MED/93211206; Mok J; Regional Infectious Diseases Unit, City Hospital, Edinburgh, UK.
Guidance over HIV-infected health-care workers [news]: Lancet. 1993 Apr 10;341(8850):952. Unique Identifier : AIDSLINE MED/93211217; Horton R
HIV and the aetiology of AIDS [letter; comment] [see comments]: Lancet. 1993 Apr 10;341(8850):957-8. Unique Identifier : AIDSLINE MED/93211225; Duesberg P
Rapid decline of CD4+ cells after IFN alpha treatment in HIV-1 infection [letter] [see comments]: Lancet. 1993 Apr 10;341(8850):958-9. Unique Identifier : AIDSLINE MED/93211226; Vento S; Di Perri G; Cruciani M; Garofano T; Concia E; Bassetti D
Trends in the incidence of outcomes defining acquired immunodeficiency syndrome (AIDS) in the Multicenter AIDS Cohort Study: 1985-1991.: Am J Epidemiol. 1993 Feb 15;137(4):423-38. Unique Identifier : AIDSLINE MED/93212715; Munoz A; Schrager LK; Bacellar H; Speizer I; Vermund SH; Detels R; Saah AJ; Kingsley LA; Seminara D; Phair JP; Department of Epidemiology, Johns Hopkins University School of; Hygiene and Public Health, Baltimore, MD.; Incidence of clinical outcomes defining acquired immunodeficiency syndrome (AIDS) may be expected to change as a consequence of progressive immunosuppression and use of chemoprophylaxis before the onset of AIDS. Using Poisson regression methods, we examined trends in the incidence of initial and secondary AIDS-definin
Clinical factors associated with weight loss related to infection with human immunodeficiency virus type 1 in the Multicenter AIDS Cohort Study.: Am J Epidemiol. 1993 Feb 15;137(4):439-46. Unique Identifier : AIDSLINE MED/93212716; Graham NM; Munoz A; Bacellar H; Kingsley LA; Visscher BR; Phair JP; Department of Epidemiology, Johns Hopkins University School of; Hygiene and Public Health, Baltimore, MD.; The relation between a number of potential risk factors and change in body mass index per semester was examined in a community-based cohort of 1,809 homosexual and bisexual men seropositive for human immunodeficiency virus type 1 (HIV-1). The men were followed semiannually for up to 6.5 years between 1984 and 1990. A
The effects of immune status and race on health service use among people with HIV disease.: Am J Public Health. 1993 Apr;83(4):510-4. Unique Identifier : AIDSLINE MED/93212862; Piette JD; Mor V; Mayer K; Zierler S; Wachtel T; Brown University's AIDS Program, Providence, RI.; OBJECTIVES. The purpose of this study was to examine the relationship between CD4 lymphocyte count and health service use, and to determine whether differences in the rates of service use between Whites and people of color could be identified. METHODS. Medical records for 571 HIV-infected individuals were analyzed. In
CD4+ lymphocytes are an incomplete surrogate marker for clinical progression in persons with asymptomatic HIV infection taking zidovudine [see comments]: Ann Intern Med. 1993 May 1;118(9):674-80. Unique Identifier : AIDSLINE MED/93213005; Choi S; Lagakos SW; Schooley RT; Volberding PA; Department of Epidemiology and Biostatistics, McGill University,; Montreal, Quebec, Canada.; OBJECTIVE: To determine the extent to which lymphocytes, particularly those with the CD4 surface antigen, are a surrogate marker for the development of the acquired immunodeficiency syndrome (AIDS) in persons with asymptomatic human immunodeficiency virus (HIV) infection. DESIGN: Analysis of data from the AIDS Clinica
Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS [see comments]: Ann Intern Med. 1993 May 1;118(9):681-8. Unique Identifier : AIDSLINE MED/93213006; Koot M; Keet IP; Vos AH; de Goede RE; Roos MT; Coutinho RA; Miedema F; Schellekens PT; Tersmette M; Department of Clinical Viro-Immunology, Central Laboratory of the; Netherlands Red Cross Blood Transfusion Service, Amsterdam.; OBJECTIVE: To investigate the relation between detection of syncytium-inducing (SI), human immunodeficiency virus type 1 (HIV-1) variants, rate of CD4+ cell decline, and clinical progression. DESIGN: Prospective study during a 2.5-year follow-up period; cohort study with pairwise matched controls. SETTING: The Amsterd
Estimating prognosis in HIV-1 infection [editorial; comment]: Ann Intern Med. 1993 May 1;118(9):742-4. Unique Identifier : AIDSLINE MED/93213017; Phair JP
Infection with human T-lymphotropic viruses leads to constitutive expression of leukemia inhibitory factor and interleukin-6.: Blood. 1993 Apr 1;81(7):1827-32. Unique Identifier : AIDSLINE MED/93214036; Lal RB; Rudolph D; Buckner C; Pardi D; Hooper WC; Retrovirus Diseases Branch, National Center for Infectious; Diseases, Centers for Disease Control, Atlanta, GA 30333.; Leukemia inhibitory factor (LIF), similar to interleukin-6 (IL-6), is a glycoprotein growth factor and differentiation regulator that has pleiotropic activity in several cellular systems. Recent reports of constitutive IL-6 production from spontaneously proliferating cells from human T-cell leukemia virus (HTLV)-infec
HIV-specific cytotoxic T-cell activity in an HIV-exposed but uninfected infant.: Lancet. 1993 Apr 3;341(8849):860-1. Unique Identifier : AIDSLINE MED/93218363; Rowland-Jones SL; Nixon DF; Aldhous MC; Gotch F; Ariyoshi K; Hallam N; Kroll JS; Froebel K; McMichael A; Molecular Immunology Group, Institute of Molecular Medicine, John; Radcliffe Hospital, Oxford, UK.; The factors necessary for protective immunity against HIV-1 are unknown. Important information about these factors should come from study of people at high risk of HIV infection who have not apparently become infected. Among these are the estimated 60-85% of children who may be exposed in utero or perinatally to HIV-1
Heterosexual AIDS: pessimism, pandemics, and plain hard facts [editorial; comment] [see comments]: Lancet. 1993 Apr 3;341(8849):863-4. Unique Identifier : AIDSLINE MED/93218365
Arab nations: attitudes to AIDS [news]: Lancet. 1993 Apr 3;341(8849):884-5. Unique Identifier : AIDSLINE MED/93218377; Kandela P
HTLV-II-related disease [news] [see comments]: Lancet. 1993 Apr 3;341(8849):888. Unique Identifier : AIDSLINE MED/93218380; Murphy EL
Preliminary analysis of the Concorde trial. Concorde Coordinating Committee [letter] [see comments]: Lancet. 1993 Apr 3;341(8849):889-90. Unique Identifier : AIDSLINE MED/93218381; Aboulker JP; Swart AM
Errors in predictions of the incidence and distribution of AIDS [letter; comment] [see comments]: Lancet. 1993 Apr 3;341(8849):898. Unique Identifier : AIDSLINE MED/93218399; Stewart GT
The next step in AIDS treatment [news]: Nature. 1993 Apr 8;362(6420):493. Unique Identifier : AIDSLINE MED/93218733; Maddox J
Effects of human immunodeficiency virus and immune status on magnetic resonance imaging of the brain in hemophilic subjects: results from the hemophilia growth and development study.: Pediatrics. 1993 Apr;91(4):742-6. Unique Identifier : AIDSLINE MED/93219016; Mitchell WG; Nelson MD; Contant CF; Bale JF Jr; Wilson DA; Bohan TP; Fenstermacher MJ; Department of Neurology, University of Southern California School; of Medicine.; To determine the effects of hemophilia and human immunodeficiency virus (HIV) infection on the nervous system, the authors examined the relationship of brain magnetic resonance imaging (MRI) findings to immunologic function and neurologic examination findings. Baseline examinations included physical and neurologic exa
[Porphyria cutanea tarda and human immunodeficiency virus infection]: Rev Clin Esp. 1993 Feb;192(3):120-2. Unique Identifier : AIDSLINE MED/93219613; Soriano E; Catala MT; Lacruz J; Campayo A; Lopez Aldeguer J; Perello A; Servicio de Medicina Interna, Hospital General La Fe, Valencia.; Recently, cases of porphyria cutanea tarda (PCT) have been reported associated with infection due to human immunodeficiency virus (HIV). We presented the cases of three males, former ethanol users, and which have had previously a contact with the Hepatitis B virus. In one of the patients symptomatology appeared after
[Dipeptidyl peptidase IV of peripheral blood lymphocytes in patients with primary biliary cirrhosis]: Z Gastroenterol. 1993 Feb;31(2):135-9. Unique Identifier : AIDSLINE MED/93220319; Adler D; Kurktschiev D; Subat S; Lehmann HU; Schentke KU; Medizinische Akademie Carl Custav Carus, Klinik fur Innere; Medizin, Abteilung fur Gastroenterologie, Dresden/Bundesrepublik; Deutschland.; Investigations concerning changes of dipeptidyl-peptidase IV-positive (DP IV+) lymphocytes in the peripheral blood (PBL) were undertaken in 22 patients with primary biliary cirrhosis (PBC) under therapy with ursodeoxycholic acid (750 mg/day). We found that after 4-8 weeks of therapy the number of DP IV+ PBL was raised
CD4 lymphocyte counts within 24 months of human immunodeficiency virus seroconversion. Findings in the US Navy and Marine Corps. The Navy Retroviral Working Group.: Arch Intern Med. 1993 Apr 12;153(7):869-76. Unique Identifier : AIDSLINE MED/93221342; Gorham ED; Garland FC; Mayers DL; Goforth RR; Brodine SK; Wiess PJ; McNally MS; Epidemiology Division, Naval Health Research Center, San Diego,; Calif.; BACKGROUND: Although CD4 lymphocytes are the primary target of the human immunodeficiency virus (HIV), few studies have evaluated CD4 cell counts in a large population of seroconverters with known dates of seroconversion. This study reports an analysis of CD4 lymphocyte counts and CD4 cells as a percentage of all lymp
A TH1-->TH2 switch is a critical step in the etiology of HIV infection [see comments]: Immunol Today. 1993 Mar;14(3):107-11. Unique Identifier : AIDSLINE MED/93221651; Clerici M; Shearer GM; Experimental Immunology Branch, National Cancer Institute,; National Institutes of Health, Bethesda, MD 20892.; This viewpoint proposes that an imbalance in the TH1-type and TH2-type responses contributes to the immune dysregulation associated with HIV infection, and that resistance to HIV infection and/or progression to AIDS is dependent on a TH1-->TH2 dominance. This hypothesis is based on the authors findings that: (1) prog
Weight loss in HIV-1 infection is associated with immune activation.: AIDS. 1993 Feb;7(2):175-81. Unique Identifier : AIDSLINE MED/93221720; Zangerle R; Reibnegger G; Wachter H; Fuchs D; Department of Dermatology and Venereology, University, Innsbruck,; Austria.; OBJECTIVE: To assess the risk of developing weight loss, a decline in CD4+ T-cell count and AIDS-defining infections using urinary neopterin levels and CD4+ T-cell count. DESIGN: Retrospective record review. SETTING: A primary care clinic for patients at any stage of HIV infection at the University Hospital in Innsbru
The efficacy and safety of zidovudine alone or as cotherapy with acyclovir for the treatment of patients with AIDS and AIDS-related complex: a double-blind randomized trial. European-Australian Collaborative Group.: AIDS. 1993 Feb;7(2):197-207. Unique Identifier : AIDSLINE MED/93221723; Cooper DA; Pehrson PO; Pedersen C; Moroni M; Oksenhendler E; Rozenbaum W; Clumeck N; Faber V; Stille W; Hirschel B; et al; National Centre in HIV Epidemiology and Clinical Research, St; Vincent's Hospital Medical Centre, Sydney, NSW, Australia.; OBJECTIVE: To evaluate the efficacy and safety of zidovudine (ZDV) at a maintenance dose of 250 mg every 6 h alone or as cotherapy with acyclovir (ACV; 800 mg every 6 h) as treatment for AIDS and AIDS-related complex (ARC). DESIGN: Double-blind, randomized, placebo-controlled cl
Non-HIV-1 CD4+ lymphocyte depletion in a patient with an acquired immunodeficiency syndrome of unknown etiology [letter]: AIDS. 1993 Feb;7(2):284-5. Unique Identifier : AIDSLINE MED/93221738; Schinazi RF; Del Bene VE
Epidemiologic models, clinical decision-making, and the role of oral lesions [letter]: AIDS. 1993 Feb;7(2):285-6. Unique Identifier : AIDSLINE MED/93221739; Katz MH; Greenspan D; Greenspan JS
Detection of HIV-specific cell-mediated cytotoxicity in the peripheral blood from infected children.: J Immunol. 1993 Apr 15;150(8 Pt 1):3569-81. Unique Identifier : AIDSLINE MED/93224764; Buseyne F; Blanche S; Schmitt D; Griscelli C; Riviere Y; Unite de Virologie et d'Immunologie Cellulaire, URA CNRS 1157,; Institut Pasteur, Paris.; Cytotoxic T lymphocytes may play a significant role in containing the spread of HIV in infected individuals. Although HIV-infection is associated with immune suppression, a vigorous T lymphocyte response has been detected in infected adults. HIV can be transmitted from mother to child, either during pregnancy, when di
USA: battle of AIDS vaccine trial [news]: Lancet. 1993 Apr 17;341(8851):1014. Unique Identifier : AIDSLINE MED/93225643; Rowe PM
Immediate versus deferred zidovudine [letter; comment]: Lancet. 1993 Apr 17;341(8851):1022-3. Unique Identifier : AIDSLINE MED/93225651; Peto R; Collins R
Immediate versus deferred zidovudine [letter; comment]: Lancet. 1993 Apr 17;341(8851):1023. Unique Identifier : AIDSLINE MED/93225652; Saah AJ
Sex and sample size [letter]: Lancet. 1993 Apr 17;341(8851):1023. Unique Identifier : AIDSLINE MED/93225653; Blower S
Are there two types of response to HIV? [letter; comment]: Lancet. 1993 Apr 17;341(8851):1023-4. Unique Identifier : AIDSLINE MED/93225654; Phillips AN; Sabin CA; Bofill M; Janossy G; Lee CA
Attitudes of dentists to HIV-positive patients [letter] [see comments]: Lancet. 1993 Apr 17;341(8851):1032. Unique Identifier : AIDSLINE MED/93225674; Porter S; el-Maaytah M; Afonso W; Scully C
Why anonymous? [editorial; comment] [see comments]: Lancet. 1993 Apr 24;341(8852):1059-60. Unique Identifier : AIDSLINE MED/93225714
HIV seroconversion after occupational exposure despite early prophylactic zidovudine therapy [see comments]: Lancet. 1993 Apr 24;341(8852):1077-8. Unique Identifier : AIDSLINE MED/93225724
Viral dynamics in primary HIV-1 infection [letter]: Lancet. 1993 Apr 24;341(8852):1099. Unique Identifier : AIDSLINE MED/93225753; Piatak M Jr; Yang LC; Luk KC; Lifson JD; Saag MS; Clark SJ; Kappes JC; Hahn BH; Shaw GM
High plasma lipoprotein (a) in HIV-positive patients [letter; comment]: Lancet. 1993 Apr 24;341(8852):1099-100. Unique Identifier : AIDSLINE MED/93225754; Constans J; Pellegrin JL; Peuchant E; Dumon MF; Simonoff M; Clerc M; Leng B; Conri C
Zalcitabine compared with zidovudine in patients with advanced HIV-1 infection who received previous zidovudine therapy [see comments]: Ann Intern Med. 1993 May 15;118(10):762-9. Unique Identifier : AIDSLINE MED/93228268; Fischl MA; Olson RM; Follansbee SE; Lalezari JP; Henry DH; Frame PT; Remick SC; Salgo MP; Lin AH; Nauss-Karol C; et al; University of Miami School of Medicine, Department of Medicine,; FL 33101.; OBJECTIVE: To evaluate the safety and efficacy of zalcitabine (also known as dideoxycytidine [ ddC ]) in patients with advanced human immunodeficiency virus (HIV) infection. DESIGN: Open-label, randomized study. SETTING: AIDS Clinical Trials Units, univ
Serum levels of soluble CD8, neopterin, beta 2-microglobulin and p24 antigen as indicators of disease progression in children with AIDS on zidovudine therapy.: AIDS. 1993 Mar;7(3):369-73. Unique Identifier : AIDSLINE MED/93228885; Siller L; Martin NL; Kostuchenko P; Beckett L; Rautonen J; Cheng SC; Wara DW; Department of Pediatrics, University of California, San; Francisco.; OBJECTIVE: To test the hypothesis that serum levels of soluble markers in children change after initiation of zidovudine therapy and that the extent and pattern of these longitudinal changes correlates with clinical outcome. PATIENTS AND METHODS: We measured serum levels of soluble CD8, neopterin, beta 2-microglobulin
Treatment with corticosteroids--a risk factor for the development of clinical cytomegalovirus disease in AIDS.: AIDS. 1993 Mar;7(3):375-8. Unique Identifier : AIDSLINE MED/93228886; Nelson MR; Erskine D; Hawkins DA; Gazzard BG; HIV Unit, Westminster Hospital, London, UK.; OBJECTIVE: To assess the frequency with which HIV-seropositive patients treated with corticosteroids develop cytomegalovirus ( CMV ) disease. DESIGN: Retrospective case-controlled study. METHODS: All 130 patients receiving syst
Detection of zidovudine-resistant variants of HIV-1 in genital fluids [letter]: AIDS. 1993 Mar;7(3):433-4. Unique Identifier : AIDSLINE MED/93228895; Wainberg MA; Beaulieu R; Tsoukas C; Thomas R
Human T-lymphotropic virus (HTLV) types I and II: seroprevalence among intravenous drug users in continental France. Retrovirus Study Group of the French Society of Blood Transfusion [letter] [see comments]: AIDS. 1993 Mar;7(3):440-1. Unique Identifier : AIDSLINE MED/93228902; Coste J; Lemaire JM; Courouce AM; Canavaggio M
Zidovudine susceptibility testing of human immunodeficiency virus type 1 (HIV) clinical isolates.: J Virol Methods. 1993 Mar;41(3):297-310. Unique Identifier : AIDSLINE MED/93232119; Shafer RW; Kozal MJ; Katzenstein DA; Lipil WH; Johnstone IF; Merigan TC; AIDS Clinical Trials Unit, Center for AIDS Research, Stanford,; CA.; Traditional antiviral susceptibility testing methods using cell lines can be applied to no more than about 30% of clinical HIV isolates (Larder et al., 1989a; Fenyo et al., 1989). We tested the cell-free supernatant from low passage clinical HIV isolates using donor peripheral blood mononuclear cells (PBMC). Drug susc
Fluconazole once a week as secondary prophylaxis against oropharyngeal candidiasis in HIV-infected patients. A double-blind placebo-controlled study.: Med J Aust. 1993 Mar 1;158(5):312-6. Unique Identifier : AIDSLINE MED/93233520; Marriott DJ; Jones PD; Hoy JF; Speed BR; Harkness JL; Microbiology Department, St Vincent's Hospital, Darlinghurst,; NSW.; OBJECTIVE: To assess the efficacy and tolerance of fluconazole (150 mg oral dose, once a week) in the prevention of recurrent oropharyngeal candidiasis in patients with moderate to severe human immunodeficiency virus (HIV) infection. DESIGN: A randomised, double-blind, placebo-controlled trial. PATIENTS: Eighty-four p
Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures.: Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3256-9. Unique Identifier : AIDSLINE MED/93234475; Dawson VL; Dawson TM; Uhl GR; Snyder SH; National Institute on Drug Abuse, Addiction Research Center,; Baltimore, MD 21224.; The human immunodeficiency virus type 1 coat protein, gp120, kills neurons in primary cortical cultures at low picomolar concentrations. The toxicity requires external glutamate and calcium and is blocked by glutamate receptor antagonists. Nitric oxide (NO) contributes to gp120 toxicity, since nitroarginine, an inhibi
[Prevention of risks related to blood transfusions]: Rev Med Brux. 1993 Mar;14(3):59-62. Unique Identifier : AIDSLINE MED/93234870; Dupont E; Lambermont M; Service d'Immunologie, Hematologie et Transfusion, Hopital; Erasme, Bruxelles.; During the past decade, the major fears of transfusion medicine were blood-transmitted viral diseases (hepatitis, AIDS). By applying strict rules at each step of blood donation, it can now be considered that this risk is reduced to a minimal level. Furthermore, new technologies (leukocyte removal filters, cytapheresis
[Comparative study of various biological markers in HIV 1 infection]: Acta Med Port. 1993 Jan;6(1):5-9. Unique Identifier : AIDSLINE MED/93235692; Serra JE; Pombo V; Corte-Real R; da Cunha S; Melico-Silvestre A; Clinica de Doencas Infecciosas, Hospital da Universidade de; Coimbra.; A study was performed on 51 human immunodeficiency virus (HIV 1)-infected patients with a previous history of drug abuse. By the CDC staging system for HIV infection they were mainly in advanced stages of that infection, 67% were in IV-A and 8% in IV-C1. Patients were divided in two groups, one composed of 33 individu
AIDS without detectable HIV: a case report.: Am J Med. 1993 Apr;94(4):442-3. Unique Identifier : AIDSLINE MED/93235871; Tijhuis GJ; Huisman HG; Roos MT; Kauffmann RH; Municipal Hospital Leyenburg, The Hague, The Netherlands.
Surrogate markers for assessing treatment response in HIV disease.: Ann Pharmacother. 1993 Apr;27(4):450-5. Unique Identifier : AIDSLINE MED/93237648; Rathbun RC; Section of Pharmacy Practice, College of Pharmacy, University of; Oklahoma, Oklahoma City 73190.; OBJECTIVE: To provide an awareness of the issues surrounding the selection and utility of surrogate markers to evaluate treatment response for new antiretroviral therapies for HIV infection. DATA SOURCES: A MEDLINE search of applicable articles published between 1987 to the present, including clinical trials, commenta
Zalcitabine.: Ann Pharmacother. 1993 Apr;27(4):480-9. Unique Identifier : AIDSLINE MED/93237652; Shelton MJ; O'Donnell AM; Morse GD; American Foundation for AIDS Research, Center for Clinical; Pharmacy Research, Buffalo, NY.; OBJECTIVE: To review the chemistry, intracellular metabolism, pharmacokinetics, and clinical trials of zalcitabine (2 3 -dideoxycytidine, ddC ). DATA SOURCES: English-language articles and conference procedings. The indexing terms used were zalcitabine
Unique T-helper leukaemia with cytoplasmic granules and convoluted nuclei.: Leuk Lymphoma. 1993 Jan;9(1-2):165-7. Unique Identifier : AIDSLINE MED/93237806; Watanabe M; Shimamoto Y; Sano M; Yamaguchi M; Department of Internal Medicine, Saga Medical School, Japan.; An unusual case of CD4+ helper T-cell lymphocytic leukaemia is reported in a 67-year-old Japanese woman. CD4+ cells showed convoluted nuclei and dense cytoplasmic granules, features usually present in CD8+ large granular lymphocytes and disorders of this particular cell type. Serum did not show antibodies to HTLV-I an
Porphyria cutanea tarda in a patient with hairy cell leukemia.: Cutis. 1993 Apr;51(4):251-2. Unique Identifier : AIDSLINE MED/93238521; Hacker SM; Berkwitz M; Cody R; Department of Internal Medicine, University of Michigan; Hospitals, Ann Arbor.; The case of porphyria cutanea tarda occurring in a patient treated for hairy cell leukemia is presented. Porphyria cutanea tarda has recently been associated with a variety of hematologic disorders and the acquired immunodeficiency syndrome. Potential mechanisms explaining this association are discussed.
Absence of HTLV-I infection among seronegative subjects in an endemic area of Japan.: Int J Cancer. 1993 Apr 22;54(1):16-9. Unique Identifier : AIDSLINE MED/93239375; Kinoshita T; Imamura J; Nagai H; Ito M; Ito S; Ikeda S; Nagatomo M; Tajima K; Shimotohno K; Virology Division, National Cancer Center Research Institute,; Tokyo, Japan.; To examine the prevalence of infection by human T-cell leukemia virus type I (HTLV-I) among seronegative subjects, healthy subjects on Tsushima Island, Japan , where the infection is endemic, were evaluated. A total of 209 healthy adults were examined for HTLV-I provirus in periphera
New AIDS definition effective 1993 [news]: Infect Control Hosp Epidemiol. 1993 Mar;14(3):178. Unique Identifier : AIDSLINE MED/93239980
The impact of new technology on the laboratory's contribution to the diagnosis and management of mycobacterial disease.: Kekkaku. 1993 Feb;68(2):113-29. Unique Identifier : AIDSLINE MED/93240742; Wayne LG; Tuberculosis Research Laboratory, Department of Veterans Affairs; Medical Center, Long Beach, California 90822.; From the time of the discovery of the tubercle bacillus in the late nineteenth century until the introduction of chemotherapy in the mid-twentieth, the role of the laboratory in the management of tuberculosis was limited because the treatment of the disease was nonspecific. The advent of specific chemotherapy and the
Primary prophylaxis against Pneumocystis carinii pneumonia [letter; comment]: N Engl J Med. 1993 May 20;328(20):1499. Unique Identifier : AIDSLINE MED/93241249; Tarabey R
Balanced immunity. Would killing some T cells slow the progress of AIDS? [news]: Sci Am. 1993 May;268(5):22-4. Unique Identifier : AIDSLINE MED/93242378; Rennie J
Rapid loss of CD4+ T cells in human-PBL-SCID mice by noncytopathic HIV isolates.: Science. 1993 Apr 30;260(5108):689-92. Unique Identifier : AIDSLINE MED/93242397; Mosier DE; Gulizia RJ; MacIsaac PD; Torbett BE; Levy JA; Department of Immunology, Scripps Research Institute, La Jolla,; CA 92037.; Human immunodeficiency virus (HIV) isolates differ in cell tropism, replication, pathogenicity, and syncytial induction in vitro. CD4+ T cells were enumerated in severe combined immunodeficient mice transplanted with human peripheral blood leukocytes (hu-PBL-SCID mice) and infected with HIV isolates with different in
[Studying the course of HIV-1 infection in cell culture (see comments)]: Orv Hetil. 1993 Apr 11;134(15):803-9. Unique Identifier : AIDSLINE MED/93226389; Ongradi J; Szilagyi FJ; Laird MH; Ceccherini-Nelli L; Pistello M; Bendinelli M; Glasgow-i Egyetem, Virologiai Intezet, Nagy-Britannia.; The hallmark of AIDS is the gradual loss of CD4+ T-lymphocytes, in spite of their infection in low ratio. The pathomechanism is hardly known, therefore, the production of HIV-1 and certain aspects of cell death were studied. Infectivity was decreased by the acidification of culture media. C8166 cells transformed by HT
[Infection risk caused by blood or blood products (editorial) (see comments)]: Dtsch Med Wochenschr. 1993 Apr 8;118(14):520-2. Unique Identifier : AIDSLINE MED/93223598; Gurtler L; Schramm W; Max-von-Pettenhofer-Institut, Hygiene und Medizinische; Mikrobiologie der Universitat, Munchen.
HIV is no longer latent, says NIAID's Fauci [news]: Biotechnology (N Y). 1993 Jan;11(1):16-7. Unique Identifier : AIDSLINE MED/93207720; Edgington SM
Who's who in European antibiotech. Taking a look at public interest and environmental groups that take a special interest in biotechnology.: Biotechnology (N Y). 1993 Jan;11(1):44-8. Unique Identifier : AIDSLINE MED/93207723; Dixon B
[The piriformis muscle syndrome due to pyomyositis (letter; comment)]: Med Clin (Barc). 1993 Mar 20;100(11):436-7. Unique Identifier : AIDSLINE MED/93218307; Picco AG; Parajua Pozo JL
Detection of B epitopes on the p24 gag protein of feline immunodeficiency virus by monoclonal antibodies.: AIDS Res Hum Retroviruses. 1993 Feb;9(2):141-6. Unique Identifier : AIDSLINE MED/93207820; Lombardi S; Bendinelli M; Garzelli C; Department of Biomedicine, University of Pisa, Italy.; Seven monoclonal antibodies were obtained after immunization of mice with purified sodium dodecyl sulfate (SDS)-disrupted feline immunodeficiency virus (FIV). Six antibodies specifically bound antigens in the cytoplasm of FIV-infected cells as determined by indirect immunofluorescence and reacted with FIV p24 gag gene
Porphyria cutanea tarda and antibodies to hepatitis C virus.: Br J Dermatol. 1993 Feb;128(2):121-3. Unique Identifier : AIDSLINE MED/93207974; Lacour JP; Bodokh I; Castanet J; Bekri S; Ortonne JP; Department of Dermatology, University of Nice, France.; We have studied the prevalence of hepatitis C virus antibodies (anti-HCV) in 13 patients suffering from sporadic porphyria cutanea tarda. The sera were tested by Abbott second-generation enzyme immunoassay; seropositivity was confirmed by Ortho second-generation recombinant immunoblot assay. Ten cases (76.1%) were ant
Two highly antigenic sites in the human immunodeficiency virus type 1 reverse transcriptase.: J Clin Microbiol. 1993 Mar;31(3):588-92. Unique Identifier : AIDSLINE MED/93210081; Bjorling E; Boucher CA; Samuelsson A; Wolfs TF; Utter G; Norrby E; Chiodi F; Department of Virology, Karolinska Institute, Stockholm, Sweden.; Antibodies to human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) are found in the serum of the majority of infected individuals, and inhibition of RT polymerase activity by HIV-1-positive sera can be demonstrated in vitro. The binding sites of human antibodies on the protein have not yet been ident
[Nervous system diseases with immunologic disorders--present status of immunotherapy]: Nippon Naika Gakkai Zasshi. 1993 Jan 10;82(1):122-6. Unique Identifier : AIDSLINE MED/93210372; Ono R; Hamaguchi K
Non-nucleoside inhibitors of HIV-1 reverse transcriptase: molecular modeling and X-ray structure investigations.: J Med Chem. 1993 Mar 19;36(6):726-32. Unique Identifier : AIDSLINE MED/93210704; Schafer W; Friebe WG; Leinert H; Mertens A; Poll T; von der Saal W; Zilch H; Nuber B; Ziegler ML; Boehringer Mannheim GmbH, Chemical Research Department, Germany.; The structural features of a new class of non-nucleoside HIV-1 reverse transcriptase inhibitors (3) are presented. Comparison of the structural and electronic properties with those of TIBO (1) and Nevirapine (2) yields a common three-dimensional model. This model permits the improvement of the lead compound 3 by chemi
Soluble tumor necrosis factor receptor: inhibition of human immunodeficiency virus activation.: Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2335-9. Unique Identifier : AIDSLINE MED/93211956; Howard OM; Clouse KA; Smith C; Goodwin RG; Farrar WL; Biological Carcinogenesis and Development Program, Program; Resources, Inc./DynCorp, Frederick, MD.; The inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) has been shown to stimulate human immunodeficiency virus type 1 (HIV-1) replication in both chronically and acutely infected T lymphocytes and monocytes. Transcriptional activation of the HIV long terminal repeat and subsequent increase in virus product
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.: Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2537-41. Unique Identifier : AIDSLINE MED/93211997; Weissman D; Poli G; Bousseau A; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.; A platelet-activating factor antagonist, RP 55778, potently suppressed the induction of human immunodeficiency virus (HIV) expression in chronically infected promonocytic U1 cells. RP 55778 inhibited the production of reverse transcriptase activity in U1 cells stimulated with the transcriptionally active inducers of v
Overexpression of the HIV-1 gag-pol polyprotein results in intracellular activation of HIV-1 protease and inhibition of assembly and budding of virus-like particles.: Virology. 1993 Apr;193(2):661-71. Unique Identifier : AIDSLINE MED/93212498; Karacostas V; Wolffe EJ; Nagashima K; Gonda MA; Moss B; Laboratory of Viral Diseases, National Institute of Allergy and; Infectious Diseases, NIH, Bethesda, Maryland 20892.; Some retroviruses, including HIV-1, regulate the relative amounts of gag and pol gene products by a translational frameshift mechanism. The consequences of altering the ratios of the Gag and Pol proteins were tested using vaccinia virus expression vectors, in which the gag and pol genes were fused by placing them in t
Identification of HIV vaccine candidate peptides by screening random phage epitope libraries.: Virology. 1993 Apr;193(2):709-16. Unique Identifier : AIDSLINE MED/93212503; Keller PM; Arnold BA; Shaw AR; Tolman RL; Van Middlesworth F; Bondy S; Rusiecki VK; Koenig S; Zolla-Pazner S; Conard P; et al; Merck Research Laboratories, Department of Molecular and Cellular; Biology, West Point, Pennsylvania 19486.; Most synthetic HIV-1 gp120 V3 loop peptides that are used as immunogens in experimental HIV-1 vaccine studies are modeled from the naturally occurring viral gp120 V3 loops. In experimental animals these immunogens generally elicit type (or variant)-specific neutralizing antibodies that are not broadly reactive among H
Salmonella bacteraemia among young children at a rural hospital in western Zaire.: Ann Trop Paediatr. 1993;13(1):45-53. Unique Identifier : AIDSLINE MED/93213092; Green SD; Cheesbrough JS; Institut Medical Evangelique, Kimpese, Bas-Zaire.; An analysis of 206 cases of extra-intestinal Salmonella infection among children up to 60 months of age admitted to a rural hospital in western Zaire was undertaken. Most children presented with fever but without any focus of infection which was difficult to distinguish clinically
Biologic effects after a single dose of poly(I):poly(C12U) in healthy volunteers.: Antimicrob Agents Chemother. 1993 Mar;37(3):429-35. Unique Identifier : AIDSLINE MED/93213111; Hendrix CW; Margolick JB; Petty BG; Markham RB; Nerhood L; Farzadegan H; Ts'o PO; Lietman PS; Department of Medicine, School of Hygiene and Public Health,; Johns Hopkins University, Baltimore, Maryland 21205.; Poly(I):poly(C12U) (mismatched double-stranded RNA; atvogen), an interferon inducer, is active against human immunodeficiency virus in vitro. To determine the extent and duration of the biologic effects of poly(I):poly(C12U), we administered a single dose of the drug to healthy volunteers in a randomized, double-blind
Palliative care for people with HIV/AIDS: views of patients, carers and providers.: AIDS Care. 1993;5(1):105-16. Unique Identifier : AIDSLINE MED/93213876; Butters E; Higginson I; George R; McCarthy M; Department of Epidemiology and Public Health, University College; London and Middlesex School of Medicine.; This study compared the views of palliative care reported by patients, informal carers and the Community Care Team (CCT), a multidisciplinary team caring for people with late stage HIV/AIDS illness. Patients and their carers were interviewed at home, 3-4 weeks after referral to CCT. They rated nine items of the Suppor
Child development [see comments]: Curr Probl Pediatr. 1993 Feb;23(2):44-9. Unique Identifier : AIDSLINE MED/93215305; Coplan J; State University of New York-Health Science Center, Syracuse.
Evaluation of the activity of a number of antimicrobial agents against mycobacteria within mouse macrophages by a radiometric method.: J Antimicrob Chemother. 1993 Feb;31(2):289-302. Unique Identifier : AIDSLINE MED/93216564; Banerjee DK; Patel BR; Department of Medical Microbiology, St George's Hospital Medical; School, London, UK.; [3H]-uridine was incorporated by Mycobacterium bovis BCG with increasing intensity as the incubation period was increased. Rifampicin and isoniazid inhibited incorporation of the label rapidly. Similar inhibition was seen with M. tuberculosis H37Rv and several clinical isolates of M. tuberculosis both in axenic medium
Antiviral phospholipids. Anti-HIV drugs conjugated to the glycerobackbone of phospholipids.: J Biol Chem. 1993 Apr 15;268(11):7773-8. Unique Identifier : AIDSLINE MED/93216744; Pidgeon C; Markovich RJ; Liu MD; Holzer TJ; Novak RM; Keyer KA; Department of Medicinal Chemistry and Pharmacognosy, School of; Pharmacy, Purdue University, West Lafayette, Indiana 47907.; Heteroatom fatty acid analogs of myristic acid containing oxygen or sulfur substituted for the alkyl methylene groups inhibit replication of the human immunodeficiency virus (HIV) in infected cells by acting as alternative substrates during the viral protein myristoylation event. In this class of compounds, 12-methoxy
Pediatric HIV infection: a neuropsychological and educational challenge.: J Learn Disabil. 1993 Feb;26(2):92-103. Unique Identifier : AIDSLINE MED/93217359; Armstrong FD; Seidel JF; Swales TP; Department of Pediatrics, University of Miami School of Medicine.; Pediatric acquired immunodeficiency syndrome (AIDS) and human immunodeficiency virus (HIV) infection will soon be the primary infectious cause of perinatally acquired developmental disabilities in the United States . HIV encephalopathy and a variety of opportunistic infections, neoplasm
Infection of natural killer cells by human herpesvirus 6.: Nature. 1993 Apr 1;362(6419):458-62. Unique Identifier : AIDSLINE MED/93218722; Lusso P; Malnati MS; Garzino-Demo A; Crowley RW; Long EO; Gallo RC; Laboratory of Tumor Cell Biology, National Cancer Institute,; National Institutes of Health, Bethesda, Maryland 20892.; Natural killer (NK) cells are a functionally defined subset of non-T, non-B lymphocytes of bone marrow origin, which induce lysis of selected target cells, including neoplastic and virus-infected cells. The NK cell function provides an important mechanism of primary defence against viruses in vivo, as demonstrated by
Pancreatitis in human immunodeficiency virus-infected children receiving dideoxyinosine.: Pediatrics. 1993 Apr;91(4):747-51. Unique Identifier : AIDSLINE MED/93219017; Butler KM; Venzon D; Henry N; Husson RN; Mueller BU; Balis FM; Jacobsen F; Lewis LL; Pizzo PA; Pediatric Branch, National Cancer Institute, Bethesda, MD 20892.; To define predictive or contributory risk factors for pancreatitis in human immunodeficiency virus-infected children receiving dideoxyinosine (ddI), the authors evaluated 95 children, 3 months to 18 years of age, who had received ddI at 60 to 540 mg/m2 per day for a mean of 56 weeks. Pancreatitis developed in 7 patien
Prediction of common folding structures of homologous RNAs.: Nucleic Acids Res. 1993 Mar 11;21(5):1251-7. Unique Identifier : AIDSLINE MED/93219089; Han K; Kim HJ; Department of Computer Science, Rutgers University, Piscataway,; NJ 08855.; We have developed an algorithm and a computer program for simultaneously folding homologous RNA sequences. Given an alignment of M homologous sequences of length N, the program performs phylogenetic comparative analysis and predicts a common secondary structure conserved in the sequences. When the structure is not uni
A comparison of the conformations of the 5'-triphosphates of zidovudine (AZT) and thymidine bound to HIV-1 reverse transcriptase.: Biochem Biophys Res Commun. 1993 Mar 31;191(3):1166-71. Unique Identifier : AIDSLINE MED/93221482; Painter GR; Aulabaugh AE; Andrews CW; Division of Virology, Burroughs Wellcome Co., Research Triangle; Park, NC 27709.; Nuclear Overhauser effect experiments were performed at 500 MHz to determine the conformations of AZTTP and dTTP when bound to HIV-1 reverse transcriptase. The conformations of both ligands were found to be similar in the bound state. The orientation of the glycosidic angle is anti (chi = -120 degrees +/- 12 for AZTTP
Identification of four antibody-binding sites in the envelope proteins of simian immunodeficiency virus, SIVsm.: AIDS. 1993 Feb;7(2):159-65. Unique Identifier : AIDSLINE MED/93221718; Samuelsson A; Bjorling E; Putkonen P; Utter G; Chiodi F; Norrby E; Department of Virology, Karolinska Institute, Stockholm, Sweden.; OBJECTIVE: To identify antigenic regions in the envelope glycoproteins of the simian immunodeficiency virus isolate, SIVsm. METHODS: Thirty-eight peptides were synthesized and used in site-directed enzyme-linked immunosorbent assays with sera from experimentally infected macaques. RESULTS: Four antibody-binding region
Discrete regions of HIV-1 gp41 defined by syncytia-inhibiting affinity-purified human antibodies.: AIDS. 1993 Feb;7(2):167-74. Unique Identifier : AIDSLINE MED/93221719; Vanini S; Longhi R; Lazzarin A; Vigo E; Siccardi AG; Viale G; Dipartimento di Biologia e Tecnologia, H. San Raffaele, CNR; Istituto di Chimica degli Ormoni, Milan, Italy.; OBJECTIVE: Fine mapping of HIV-1 gp41 fusion-critical sites. DESIGN AND METHODS: Antibodies from human HIV-1-positive sera were affinity-purified on a panel of synthetic overlapping peptides spanning residues 526-682 of the extracellular portion of HIV-1 gp41. The syncytium-inhibiting capacity of the immunopurified an
Affinity labeling and functional analysis of the primer binding domain of HIV-1 reverse transcriptase.: Biochemistry. 1993 Apr 13;32(14):3629-37. Unique Identifier : AIDSLINE MED/93222162; Andreola ML; Tarrago-Litvak L; Levina AS; Kolocheva TI; el Dirani-Diab R; Jamkovoy VI; Khalimskaya NL; Barr PJ; Litvak S; Nevinsky GA; Institut de Biochimie Cellulaire, CNRS, Bordeaux, France.; Six affinity reagents containing chemically reactive groups, either on the phosphate residue at the 5 -end or on the 5 - or 3 -end internucleoside phosphate linkages of the oligothymidylate primers, were used to covalently modify the human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT). After covalent
Human immunodeficiency virus-related lymphoma: prognostic factors predictive of survival [letter; comment]: Cancer. 1993 May 1;71(9):2881-2. Unique Identifier : AIDSLINE MED/93223154; Taillan B; Garnier G; Schneider S; Pesce A; Fuzibet JG; Dujardin P
CR1 (CD35) and CR3 (CD11b/CD18) mediate infection of human monocytes and monocytic cell lines with complement-opsonized HIV independently of CD4.: Clin Exp Immunol. 1993 Apr;92(1):106-13. Unique Identifier : AIDSLINE MED/93223296; Thieblemont N; Haeffner-Cavaillon N; Ledur A; L'Age-Stehr J; Ziegler-Heitbrock HW; Kazatchkine MD; INSERM U 28, Hopital Broussais, Paris, France.; Peripheral blood and tissue mononuclear phagocytes serve as major viral reservoirs in HIV-infected individuals. We investigated the role of complement receptors CR1 (CD35) and CR3 (CD11b/CD18) in mediating productive infection with complement-opsonized HIV-1 and HIV-2 of cultured normal human peripheral blood monocyte
Phenotypic characterization of CD8+ T cell populations in HIV disease and in anti-HIV immunity.: Clin Exp Immunol. 1993 Apr;92(1):93-9. Unique Identifier : AIDSLINE MED/93223322; Watret KC; Whitelaw JA; Froebel KS; Bird AG; Edinburgh University Department of Medicine, Royal Infirmary, UK.; The CD8+ T cell population is believed to play an important role in the control of viral infection, both for suppression of viral replication and for cytotoxic activity against viral infected cells. Elevated numbers of CD8+ T cells have been demonstrated in HIV infection, and CD8+ cytotoxic T cell (CTL) activity is as
[Cerebral symptoms in pre- or perinatally HIV-infected children]: Dtsch Med Wochenschr. 1993 Apr 2;118(13):445-50. Unique Identifier : AIDSLINE MED/93223583; Koch S; Vocks-Hauck M; Henning S; Grosch-Worner I; Kinderklinik und Poliklinik Kaiserin-Auguste-Victoria-Haus,; Universitatsklinikum Rudolf Virchow, Berlin.; Eight of 13 children pre- or perinatally infected with the HIV virus subsequently developed neurological symptoms. Three children also had other nonspecific symptoms (fever, lymphadenopathy, diarrhoea, hepatosplenomegaly, failure to thrive and mucocutaneous thrush ). Five childr
Computer assisted signal co-localization for simultaneous detection of antigen by immunohistochemistry and DNA by non-isotopic in situ hybridization.: Histochemistry. 1993 Jan;99(1):23-7. Unique Identifier : AIDSLINE MED/93224333; Lu QL; Dover R; Histopathology Unit, Imperial Cancer Research Fund, London, UK.; A method has been developed to co-localize signals for antigen and DNA using a desktop microcomputer system (computer assisted signal co-localization). Antigens were detected by standard immunohistochemical methods and DNA was detected by non-isotopic in situ hybridization (NISH). Using this method, NISH signals can b
In vitro erythroid effects of human stem cell factor in a case of human immunodeficiency virus-related chronic parvovirus B19 induced anemia.: Hematol Pathol. 1993;7(1):23-32. Unique Identifier : AIDSLINE MED/93224419; Liesveld JL; Weissbach NE; Shafer JA; Abboud CN; Hematology Unit, University of Rochester Medical Center, NY; 14642.; Chronic B19 parvovirus infection in patients infected with human immunodeficiency virus type 1 (HIV-1) is one cause of reversible anemia in this patient group. This report describes a case of concurrent HIV-1 and B19 parvovirus infection with pure red cell aplasia in which the anemia resolved with gammaglobulin treatm
A novel integrin specificity exemplified by binding of the alpha v beta 5 integrin to the basic domain of the HIV Tat protein and vitronectin.: J Cell Biol. 1993 Apr;121(2):461-8. Unique Identifier : AIDSLINE MED/93224540; Vogel BE; Lee SJ; Hildebrand A; Craig W; Pierschbacher MD; Wong-Staal F; Ruoslahti E; La Jolla Cancer Research Foundation, California 92037.; Several studies have addressed the interaction of the HIV Tat protein with the cell surface. Our analysis of the cell attachment-promoting activity of Tat and peptides derived from it revealed that the basic domain of Tat, not the arg-gly-asp (RGD) sequence, is required for cell attachment to Tat. Affinity chromatogra
A model for reverse transcription by a dimeric enzyme [published erratum appears in J Gen Virol 1993 Sep;74(Pt 9):2037]: J Gen Virol. 1993 Apr;74 ( Pt 4):691-7. Unique Identifier : AIDSLINE MED/93224890; Cook PR; Sir William Dunn School of Pathology, University of Oxford, U.K.; A speculative model for reverse transcription of a viral RNA template into proviral dsDNA is presented. It has two essential features that are not included in current models: (i) the functional complex is dimeric, with two polymerization/RNase H sites and (ii) two templates are initially attached to the complex at the
Generation and characterization of murine monoclonal antibodies reactive against N-terminal and other regions of HIV-1 reverse transcriptase.: J Med Virol. 1993 Mar;39(3):251-9. Unique Identifier : AIDSLINE MED/93224919; Li X; Amandoron E; Wainberg MA; Parniak MA; Lady Davis Institute for Medical Research, Sir Mortimer B.; Davis-Jewish General Hospital, Montreal, Quebec, Canada.; We produced a series of monoclonal antibodies against the human immunodeficiency virus (HIV-1) reverse transcriptase by immunizing mice with either purified recombinant HIV-1 p66 protein or with recombinant vaccinia virus which expresses HIV-1 pol sequences. The antibodies generated were specific for the reverse trans
Specificity and sensitivity of 3rd generation EIA for detection of HCV antibodies among intravenous drug-users.: New Microbiol. 1993 Jan;16(1):35-42. Unique Identifier : AIDSLINE MED/93225877; Filice G; Patruno S; Campisi D; Chiesa A; Orsolini P; Debiaggi M; Bruno R; Tinelli M; Institute of Infectious Diseases, University of Pavia, Italy.; Serum samples from 487 ambulatory I.V. drug users were screened for HIV and HCV antibodies to determine the prevalence of coinfection in this high risk group for AIDS. For anti-HCV antibody screening we first used a 3rd generation EIA using, as antigen synthetic peptides which were not subjected to false positive resu
Neurotoxicity of peptide analogues of the transactivating protein tat from Maedi-Visna virus and human immunodeficiency virus.: Neuroscience. 1993 Mar;53(1):1-6. Unique Identifier : AIDSLINE MED/93226064; Hayman M; Arbuthnott G; Harkiss G; Brace H; Filippi P; Philippon V; Thomson D; Vigne R; Wright A; MRC External Scientific Staff, University of Edinburgh, U.K.; Infection by lentiviruses such as human immunodeficiency virus, Maedi-Visna virus and Caprine Arthritis Encephalitis Virus, is associated with a variety of neurological syndromes, but the mechanism by which the damage occurs to the nervous system is not known. The viruses do not infect neurons and so the neurotoxic ac
The impaired number of circulating granulocyte/macrophage progenitors (CFU-GM) in human immunodeficiency virus-type 1 infected subjects correlates with an active HIV-1 replication.: Arch Virol. 1993;129(1-4):53-64. Unique Identifier : AIDSLINE MED/93228463; Re MC; Zauli G; Furlini G; Ranieri S; Monari P; Ramazzotti E; La Placa M; Institute of Microbiology, University of Bol